465797:I6L31 RS16075
gene id: 465797:I6L31_RS16075
uniprot id: A0A8F8CPR8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

465797:I6L31 RS10470
gene id: 465797:I6L31_RS10470
uniprot id: A0A8F8CSK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

465797:I6L31 RS03850
gene id: 465797:I6L31_RS03850
uniprot id: A0A8F8CU07
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

465797:I6L31 RS15350
gene id: 465797:I6L31_RS15350
uniprot id: A0A8F8CS97
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

465797:I6L31 RS16155
gene id: 465797:I6L31_RS16155
uniprot id: A0A8F8CPS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. CntA subfamily.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of an oxygenase subunit and a reductase subunit.
messages: Converts carnitine to trimethylamine and malic semialdehyde.

465797:I6L31 RS08000
gene id: 465797:I6L31_RS08000
uniprot id: A0A8F8CXI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

465797:I6L31 RS07175
gene id: 465797:I6L31_RS07175
uniprot id: A0A8F8GKU7
names: Similarity
messages: Belongs to the YfgM family.

465797:I6L31 RS11090
gene id: 465797:I6L31_RS11090
uniprot id: A0A8F8GIR7
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

465797:I6L31 RS13905
gene id: 465797:I6L31_RS13905
uniprot id: A0A8F8CPR2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

465797:I6L31 RS10915
gene id: 465797:I6L31_RS10915
uniprot id: A0A8F8GKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

465797:I6L31 RS01060
gene id: 465797:I6L31_RS01060
uniprot id: A0A8F8CQV6
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

465797:I6L31 RS04640
gene id: 465797:I6L31_RS04640
uniprot id: A0A8F8GKF1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

465797:I6L31 RS14430
gene id: 465797:I6L31_RS14430
uniprot id: A0A8F8CS01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS05925
gene id: 465797:I6L31_RS05925
uniprot id: A0A8F8CWZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465797:I6L31 RS05650
gene id: 465797:I6L31_RS05650
uniprot id: A0A8F8CS83
names: Similarity
messages: Belongs to the Gfa family.

465797:I6L31 RS07685
gene id: 465797:I6L31_RS07685
uniprot id: A0A8F8CXL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

465797:I6L31 RS07550
gene id: 465797:I6L31_RS07550
uniprot id: A0A8F8CV83
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

465797:I6L31 RS14350
gene id: 465797:I6L31_RS14350
uniprot id: A0A8F8CU33
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

465797:I6L31 RS04270
gene id: 465797:I6L31_RS04270
uniprot id: A0A8F8CXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

465797:I6L31 RS13850
gene id: 465797:I6L31_RS13850
uniprot id: A0A8F8CV79
names: Similarity
messages: Belongs to the phosphohexose mutase family.

465797:I6L31 RS17505
gene id: 465797:I6L31_RS17505
uniprot id: A0A8F8GL97
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

465797:I6L31 RS08725
gene id: 465797:I6L31_RS08725
uniprot id: A0A8F8GJ84
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07830
gene id: 465797:I6L31_RS07830
uniprot id: A0A8F8CVB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

465797:I6L31 RS04675
gene id: 465797:I6L31_RS04675
uniprot id: A0A8F8CRF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

465797:I6L31 RS17910
gene id: 465797:I6L31_RS17910
uniprot id: A0A8F8CY91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

465797:I6L31 RS14555
gene id: 465797:I6L31_RS14555
uniprot id: A0A8F8CP92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

465797:I6L31 RS11410
gene id: 465797:I6L31_RS11410
uniprot id: A0A8F8CSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

465797:I6L31 RS12305
gene id: 465797:I6L31_RS12305
uniprot id: A0A8F8CTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS15315
gene id: 465797:I6L31_RS15315
uniprot id: A0A8F8GMY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

465797:I6L31 RS16125
gene id: 465797:I6L31_RS16125
uniprot id: A0A8F8GLM6
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS15980
gene id: 465797:I6L31_RS15980
uniprot id: A0A8F8CQD5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11295
gene id: 465797:I6L31_RS11295
uniprot id: A0A8F8CNZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

465797:I6L31 RS10945
gene id: 465797:I6L31_RS10945
uniprot id: A0A8F8CN35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS05110
gene id: 465797:I6L31_RS05110
uniprot id: A0A8F8CS28
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465797:I6L31 RS14965
gene id: 465797:I6L31_RS14965
uniprot id: A0A8F8GL89
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS05175
gene id: 465797:I6L31_RS05175
uniprot id: A0A8F8GLE4
names: Similarity
messages: Belongs to the PhzF family.

465797:I6L31 RS03165
gene id: 465797:I6L31_RS03165
uniprot id: A0A8F8CRG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

465797:I6L31 RS03525
gene id: 465797:I6L31_RS03525
uniprot id: A0A8F8CW35
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

465797:I6L31 RS02695
gene id: 465797:I6L31_RS02695
uniprot id: A0A8F8CTM0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465797:I6L31 RS13575
gene id: 465797:I6L31_RS13575
uniprot id: A0A8F8CTW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

465797:I6L31 RS15575
gene id: 465797:I6L31_RS15575
uniprot id: A0A8F8CPL1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

465797:I6L31 RS08070
gene id: 465797:I6L31_RS08070
uniprot id: A0A8F8CSQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

465797:I6L31 RS14045
gene id: 465797:I6L31_RS14045
uniprot id: A0A8F8GKZ5
names: Similarity
messages: Belongs to the IucA/IucC family.

465797:I6L31 RS01330
gene id: 465797:I6L31_RS01330
uniprot id: A0A8F8CQC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

465797:I6L31 RS06560
gene id: 465797:I6L31_RS06560
uniprot id: A0A8F8CS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

465797:I6L31 RS14805
gene id: 465797:I6L31_RS14805
uniprot id: A0A8F8GL79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

465797:I6L31 RS14140
gene id: 465797:I6L31_RS14140
uniprot id: A0A8F8CPT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

465797:I6L31 RS11820
gene id: 465797:I6L31_RS11820
uniprot id: A0A8F8CND7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

465797:I6L31 RS04900
gene id: 465797:I6L31_RS04900
uniprot id: A0A8F8CWK3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

465797:I6L31 RS09575
gene id: 465797:I6L31_RS09575
uniprot id: A0A8F8CMV2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

465797:I6L31 RS02235
gene id: 465797:I6L31_RS02235
uniprot id: A0A8F8CQN0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465797:I6L31 RS05965
gene id: 465797:I6L31_RS05965
uniprot id: A0A8F8CWY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

465797:I6L31 RS04895
gene id: 465797:I6L31_RS04895
uniprot id: A0A8F8CT70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS04240
gene id: 465797:I6L31_RS04240
uniprot id: A0A8F8CRT9
names: Similarity
messages: Belongs to the group II decarboxylase family.

465797:I6L31 RS15790
gene id: 465797:I6L31_RS15790
uniprot id: A0A8F8GL98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

465797:I6L31 RS04850
gene id: 465797:I6L31_RS04850
uniprot id: A0A8F8CS00
names: Similarity
messages: Belongs to the UPF0246 family.

465797:I6L31 RS04145
gene id: 465797:I6L31_RS04145
uniprot id: A0A8F8GL85
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

465797:I6L31 RS14000
gene id: 465797:I6L31_RS14000
uniprot id: A0A8F8CP22
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

465797:I6L31 RS01410
gene id: 465797:I6L31_RS01410
uniprot id: A0A8F8CVF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

465797:I6L31 RS11435
gene id: 465797:I6L31_RS11435
uniprot id: A0A8F8GKJ8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

465797:I6L31 RS05800
gene id: 465797:I6L31_RS05800
uniprot id: A0A8F8GKL7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS10215
gene id: 465797:I6L31_RS10215
uniprot id: A0A8F8CN18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

465797:I6L31 RS14415
gene id: 465797:I6L31_RS14415
uniprot id: A0A8F8CVF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

465797:I6L31 RS17205
gene id: 465797:I6L31_RS17205
uniprot id: A0A8F8CZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS04700
gene id: 465797:I6L31_RS04700
uniprot id: A0A8F8CWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465797:I6L31 RS02440
gene id: 465797:I6L31_RS02440
uniprot id: A0A8F8GLT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

465797:I6L31 RS02645
gene id: 465797:I6L31_RS02645
uniprot id: A0A8F8GK33
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

465797:I6L31 RS10875
gene id: 465797:I6L31_RS10875
uniprot id: A0A8F8CQS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

465797:I6L31 RS08235
gene id: 465797:I6L31_RS08235
uniprot id: A0A8F8CVG4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

465797:I6L31 RS12205
gene id: 465797:I6L31_RS12205
uniprot id: A0A8F8CT59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

465797:I6L31 RS17035
gene id: 465797:I6L31_RS17035
uniprot id: A0A8F8CTK6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

465797:I6L31 RS01390
gene id: 465797:I6L31_RS01390
uniprot id: A0A8F8GKR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

465797:I6L31 RS01510
gene id: 465797:I6L31_RS01510
uniprot id: A0A8F8CQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS08480
gene id: 465797:I6L31_RS08480
uniprot id: A0A8F8GIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

465797:I6L31 RS15110
gene id: 465797:I6L31_RS15110
uniprot id: A0A8F8CUD3
names: Similarity
messages: Belongs to the CopC family.

465797:I6L31 RS15000
gene id: 465797:I6L31_RS15000
uniprot id: A0A8F8CPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

465797:I6L31 RS09000
gene id: 465797:I6L31_RS09000
uniprot id: A0A8F8CNC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

465797:I6L31 RS12225
gene id: 465797:I6L31_RS12225
uniprot id: A0A8F8GKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

465797:I6L31 RS02350
gene id: 465797:I6L31_RS02350
uniprot id: A0A8F8CVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

465797:I6L31 RS04280
gene id: 465797:I6L31_RS04280
uniprot id: A0A8F8CWD7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

465797:I6L31 RS03610
gene id: 465797:I6L31_RS03610
uniprot id: A0A8F8CVZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

465797:I6L31 RS02445
gene id: 465797:I6L31_RS02445
uniprot id: A0A8F8GKY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS05510
gene id: 465797:I6L31_RS05510
uniprot id: A0A8F8GM11
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465797:I6L31 RS15760
gene id: 465797:I6L31_RS15760
uniprot id: A0A8F8CSE9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

465797:I6L31 RS08270
gene id: 465797:I6L31_RS08270
uniprot id: A0A8F8GMR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

465797:I6L31 RS01610
gene id: 465797:I6L31_RS01610
uniprot id: A0A8F8CWQ4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

465797:I6L31 RS02410
gene id: 465797:I6L31_RS02410
uniprot id: A0A8F8CTJ0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

465797:I6L31 RS06670
gene id: 465797:I6L31_RS06670
uniprot id: A0A8F8CX63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS10360
gene id: 465797:I6L31_RS10360
uniprot id: A0A8F8CNQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

465797:I6L31 RS06550
gene id: 465797:I6L31_RS06550
uniprot id: A0A8F8CS24
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

465797:I6L31 RS02740
gene id: 465797:I6L31_RS02740
uniprot id: A0A8F8GM61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS05485
gene id: 465797:I6L31_RS05485
uniprot id: A0A8F8CWU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS14040
gene id: 465797:I6L31_RS14040
uniprot id: A0A8F8GJ85
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS06235
gene id: 465797:I6L31_RS06235
uniprot id: A0A8F8GKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

465797:I6L31 RS01305
gene id: 465797:I6L31_RS01305
uniprot id: A0A8F8GKR4
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

465797:I6L31 RS02315
gene id: 465797:I6L31_RS02315
uniprot id: A0A8F8CVQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS05670
gene id: 465797:I6L31_RS05670
uniprot id: A0A8F8CQJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

465797:I6L31 RS03830
gene id: 465797:I6L31_RS03830
uniprot id: A0A8F8CW86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

465797:I6L31 RS11125
gene id: 465797:I6L31_RS11125
uniprot id: A0A8F8CNY1
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

465797:I6L31 RS11365
gene id: 465797:I6L31_RS11365
uniprot id: A0A8F8GKN5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

465797:I6L31 RS11990
gene id: 465797:I6L31_RS11990
uniprot id: A0A8F8CP68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

465797:I6L31 RS10695
gene id: 465797:I6L31_RS10695
uniprot id: A0A8F8CU65
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS04945
gene id: 465797:I6L31_RS04945
uniprot id: A0A8F8CRJ4
names: Similarity
messages: Belongs to the DinB family.

465797:I6L31 RS12655
gene id: 465797:I6L31_RS12655
uniprot id: A0A8F8CTB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

465797:I6L31 RS06480
gene id: 465797:I6L31_RS06480
uniprot id: A0A8F8CS57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

465797:I6L31 RS10140
gene id: 465797:I6L31_RS10140
uniprot id: A0A8F8CQI0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

465797:I6L31 RS09135
gene id: 465797:I6L31_RS09135
uniprot id: A0A8F8GJA6
names: Similarity
messages: Belongs to the LOG family.

465797:I6L31 RS08775
gene id: 465797:I6L31_RS08775
uniprot id: A0A8F8CTK4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

465797:I6L31 RS14220
gene id: 465797:I6L31_RS14220
uniprot id: A0A8F8CPU5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS15180
gene id: 465797:I6L31_RS15180
uniprot id: A0A8F8CS79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

465797:I6L31 RS03190
gene id: 465797:I6L31_RS03190
uniprot id: A0A8F8CTS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

465797:I6L31 RS12215
gene id: 465797:I6L31_RS12215
uniprot id: A0A8F8CRA1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

465797:I6L31 RS04215
gene id: 465797:I6L31_RS04215
uniprot id: A0A8F8GM34
names: Similarity
messages: Belongs to the peptidase S49 family.

465797:I6L31 RS08315
gene id: 465797:I6L31_RS08315
uniprot id: A0A8F8CST1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

465797:I6L31 RS06325
gene id: 465797:I6L31_RS06325
uniprot id: A0A8F8CZ44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS01870
gene id: 465797:I6L31_RS01870
uniprot id: A0A8F8GLP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS04445
gene id: 465797:I6L31_RS04445
uniprot id: A0A8F8CXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

465797:I6L31 RS15725
gene id: 465797:I6L31_RS15725
uniprot id: A0A8F8GLK0
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07020
gene id: 465797:I6L31_RS07020
uniprot id: A0A8F8CT88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

465797:I6L31 RS14620
gene id: 465797:I6L31_RS14620
uniprot id: A0A8F8GL30
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

465797:I6L31 RS13680
gene id: 465797:I6L31_RS13680
uniprot id: A0A8F8CRP9
names: Similarity
messages: Belongs to the fabD family.

465797:I6L31 RS15735
gene id: 465797:I6L31_RS15735
uniprot id: A0A8F8CQA5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

465797:I6L31 RS08580
gene id: 465797:I6L31_RS08580
uniprot id: A0A8F8GK83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

465797:I6L31 RS15540
gene id: 465797:I6L31_RS15540
uniprot id: A0A8F8GJH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

465797:I6L31 RS18210
gene id: 465797:I6L31_RS18210
uniprot id: A0A8F8CW60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

465797:I6L31 RS04580
gene id: 465797:I6L31_RS04580
uniprot id: A0A8F8CRX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

465797:I6L31 RS16520
gene id: 465797:I6L31_RS16520
uniprot id: A0A8F8GN96
names: Similarity
messages: Belongs to the type IA topoisomerase family.

465797:I6L31 RS09910
gene id: 465797:I6L31_RS09910
uniprot id: A0A8F8CMU4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

465797:I6L31 RS03480
gene id: 465797:I6L31_RS03480
uniprot id: A0A8F8GM40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

465797:I6L31 RS05320
gene id: 465797:I6L31_RS05320
uniprot id: A0A8F8CXW7
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

465797:I6L31 RS03375
gene id: 465797:I6L31_RS03375
uniprot id: A0A8F8GLY6
names: Similarity
messages: Belongs to the peptidase S51 family.

465797:I6L31 RS15625
gene id: 465797:I6L31_RS15625
uniprot id: A0A8F8GN44
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

465797:I6L31 RS13615
gene id: 465797:I6L31_RS13615
uniprot id: A0A8F8CTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS14795
gene id: 465797:I6L31_RS14795
uniprot id: A0A8F8GK72
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465797:I6L31 RS14610
gene id: 465797:I6L31_RS14610
uniprot id: A0A8F8CS21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

465797:I6L31 RS08385
gene id: 465797:I6L31_RS08385
uniprot id: A0A8F8CSQ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465797:I6L31 RS03140
gene id: 465797:I6L31_RS03140
uniprot id: A0A8F8GK61
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

465797:I6L31 RS15995
gene id: 465797:I6L31_RS15995
uniprot id: A0A8F8CPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

465797:I6L31 RS01835
gene id: 465797:I6L31_RS01835
uniprot id: A0A8F8CQP2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

465797:I6L31 RS13335
gene id: 465797:I6L31_RS13335
uniprot id: A0A8F8CV22
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

465797:I6L31 RS07045
gene id: 465797:I6L31_RS07045
uniprot id: A0A8F8CXC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

465797:I6L31 RS10645
gene id: 465797:I6L31_RS10645
uniprot id: A0A8F8GKF7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465797:I6L31 RS03810
gene id: 465797:I6L31_RS03810
uniprot id: A0A8F8GL65
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS15955
gene id: 465797:I6L31_RS15955
uniprot id: A0A8F8GJK2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS03575
gene id: 465797:I6L31_RS03575
uniprot id: A0A8F8CRL7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS06515
gene id: 465797:I6L31_RS06515
uniprot id: A0A8F8GMF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

465797:I6L31 RS09355
gene id: 465797:I6L31_RS09355
uniprot id: A0A8F8CSK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

465797:I6L31 RS04335
gene id: 465797:I6L31_RS04335
uniprot id: A0A8F8CRH8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS09390
gene id: 465797:I6L31_RS09390
uniprot id: A0A8F8CSF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

465797:I6L31 RS07510
gene id: 465797:I6L31_RS07510
uniprot id: A0A8F8GMZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

465797:I6L31 RS13140
gene id: 465797:I6L31_RS13140
uniprot id: A0A8F8CRL1
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS13065
gene id: 465797:I6L31_RS13065
uniprot id: A0A8F8CRK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

465797:I6L31 RS09415
gene id: 465797:I6L31_RS09415
uniprot id: A0A8F8GKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS06890
gene id: 465797:I6L31_RS06890
uniprot id: A0A8F8CX56
names: Similarity
messages: Belongs to the ApbE family.

465797:I6L31 RS03435
gene id: 465797:I6L31_RS03435
uniprot id: A0A8F8CW24
names: Similarity
messages: Belongs to the HSP15 family.

465797:I6L31 RS08125
gene id: 465797:I6L31_RS08125
uniprot id: A0A8F8GMW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

465797:I6L31 RS07245
gene id: 465797:I6L31_RS07245
uniprot id: A0A8F8CX96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

465797:I6L31 RS01735
gene id: 465797:I6L31_RS01735
uniprot id: A0A8F8CVJ4
names: Similarity
messages: Belongs to the UPF0319 family.

465797:I6L31 RS14590
gene id: 465797:I6L31_RS14590
uniprot id: A0A8F8CVH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

465797:I6L31 RS17920
gene id: 465797:I6L31_RS17920
uniprot id: A0A8F8CW28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

465797:I6L31 RS03970
gene id: 465797:I6L31_RS03970
uniprot id: A0A8F8CSS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

465797:I6L31 RS13045
gene id: 465797:I6L31_RS13045
uniprot id: A0A8F8CUZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

465797:I6L31 RS09615
gene id: 465797:I6L31_RS09615
uniprot id: A0A8F8GJC8
names: Similarity
messages: Belongs to the BolA/IbaG family.

465797:I6L31 RS07755
gene id: 465797:I6L31_RS07755
uniprot id: A0A8F8GMU1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

465797:I6L31 RS10705
gene id: 465797:I6L31_RS10705
uniprot id: A0A8F8CSU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

465797:I6L31 RS02765
gene id: 465797:I6L31_RS02765
uniprot id: A0A8F8CQT5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS01000
gene id: 465797:I6L31_RS01000
uniprot id: A0A8F8CQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465797:I6L31 RS02270
gene id: 465797:I6L31_RS02270
uniprot id: A0A8F8CTH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

465797:I6L31 RS10345
gene id: 465797:I6L31_RS10345
uniprot id: A0A8F8GJG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Cytoplasm
messages: Heterotetramer composed of ParC and ParE.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

465797:I6L31 RS01640
gene id: 465797:I6L31_RS01640
uniprot id: A0A8F8GKT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

465797:I6L31 RS08035
gene id: 465797:I6L31_RS08035
uniprot id: A0A8F8GLW1
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

465797:I6L31 RS12450
gene id: 465797:I6L31_RS12450
uniprot id: A0A8F8CNK3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

465797:I6L31 RS05445
gene id: 465797:I6L31_RS05445
uniprot id: A0A8F8GMA1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS11275
gene id: 465797:I6L31_RS11275
uniprot id: A0A8F8GKI8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

465797:I6L31 RS13870
gene id: 465797:I6L31_RS13870
uniprot id: A0A8F8GMX7
names: Similarity
messages: Belongs to the hemerythrin family.

465797:I6L31 RS09850
gene id: 465797:I6L31_RS09850
uniprot id: A0A8F8CMX7
names: Similarity
messages: Belongs to the CmpA/NrtA family.

465797:I6L31 RS11540
gene id: 465797:I6L31_RS11540
uniprot id: A0A8F8CT91
names: Similarity
messages: Belongs to the YciI family.

465797:I6L31 RS06240
gene id: 465797:I6L31_RS06240
uniprot id: A0A8F8GME1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

465797:I6L31 RS11170
gene id: 465797:I6L31_RS11170
uniprot id: A0A8F8CQX2
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

465797:I6L31 RS12480
gene id: 465797:I6L31_RS12480
uniprot id: A0A8F8CT93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS13735
gene id: 465797:I6L31_RS13735
uniprot id: A0A8F8CTY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

465797:I6L31 RS07880
gene id: 465797:I6L31_RS07880
uniprot id: A0A8F8CSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

465797:I6L31 RS00390
gene id: 465797:I6L31_RS00390
uniprot id: A0A8F8GLS5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

465797:I6L31 RS02395
gene id: 465797:I6L31_RS02395
uniprot id: A0A8F8CQP7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

465797:I6L31 RS10525
gene id: 465797:I6L31_RS10525
uniprot id: A0A8F8CMY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

465797:I6L31 RS03515
gene id: 465797:I6L31_RS03515
uniprot id: A0A8F8CXB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

465797:I6L31 RS16575
gene id: 465797:I6L31_RS16575
uniprot id: A0A8F8CZR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Gfa family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.

465797:I6L31 RS11080
gene id: 465797:I6L31_RS11080
uniprot id: A0A8F8CSY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

465797:I6L31 RS11925
gene id: 465797:I6L31_RS11925
uniprot id: A0A8F8CR44
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS13900
gene id: 465797:I6L31_RS13900
uniprot id: A0A8F8GL27
names: Similarity
messages: Belongs to the GSP E family.

465797:I6L31 RS10225
gene id: 465797:I6L31_RS10225
uniprot id: A0A8F8CQJ0
names: Subcellular Location Annotation
messages: Cytoplasm

465797:I6L31 RS14630
gene id: 465797:I6L31_RS14630
uniprot id: A0A8F8GLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

465797:I6L31 RS09880
gene id: 465797:I6L31_RS09880
uniprot id: A0A8F8GIK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465797:I6L31 RS09105
gene id: 465797:I6L31_RS09105
uniprot id: A0A8F8CTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

465797:I6L31 RS13965
gene id: 465797:I6L31_RS13965
uniprot id: A0A8F8GKZ0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465797:I6L31 RS14055
gene id: 465797:I6L31_RS14055
uniprot id: A0A8F8GLA1
names: Similarity
messages: Belongs to the IucA/IucC family.

465797:I6L31 RS12315
gene id: 465797:I6L31_RS12315
uniprot id: A0A8F8GIY5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS12290
gene id: 465797:I6L31_RS12290
uniprot id: A0A8F8CR86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

465797:I6L31 RS02045
gene id: 465797:I6L31_RS02045
uniprot id: A0A8F8GLQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

465797:I6L31 RS01860
gene id: 465797:I6L31_RS01860
uniprot id: A0A8F8CTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS01015
gene id: 465797:I6L31_RS01015
uniprot id: A0A8F8CV35
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

465797:I6L31 RS03555
gene id: 465797:I6L31_RS03555
uniprot id: A0A8F8GL51
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

465797:I6L31 RS05080
gene id: 465797:I6L31_RS05080
uniprot id: A0A8F8GM82
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

465797:I6L31 RS04830
gene id: 465797:I6L31_RS04830
uniprot id: A0A8F8GLC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

465797:I6L31 RS08250
gene id: 465797:I6L31_RS08250
uniprot id: A0A8F8CXQ2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

465797:I6L31 RS07180
gene id: 465797:I6L31_RS07180
uniprot id: A0A8F8GMJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS15705
gene id: 465797:I6L31_RS15705
uniprot id: A0A8F8CSF3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

465797:I6L31 RS09835
gene id: 465797:I6L31_RS09835
uniprot id: A0A8F8CSQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS15750
gene id: 465797:I6L31_RS15750
uniprot id: A0A8F8CPM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

465797:I6L31 RS01420
gene id: 465797:I6L31_RS01420
uniprot id: A0A8F8CQD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

465797:I6L31 RS04770
gene id: 465797:I6L31_RS04770
uniprot id: A0A8F8CRM4
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS02850
gene id: 465797:I6L31_RS02850
uniprot id: A0A8F8CRD4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS07525
gene id: 465797:I6L31_RS07525
uniprot id: A0A8F8CXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

465797:I6L31 RS09060
gene id: 465797:I6L31_RS09060
uniprot id: A0A8F8GJA2
names: Similarity
messages: Belongs to the P(II) protein family.

465797:I6L31 RS16825
gene id: 465797:I6L31_RS16825
uniprot id: A0A8F8CYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

465797:I6L31 RS08355
gene id: 465797:I6L31_RS08355
uniprot id: A0A8F8GMR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS14655
gene id: 465797:I6L31_RS14655
uniprot id: A0A8F8CUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS11965
gene id: 465797:I6L31_RS11965
uniprot id: A0A8F8GIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

465797:I6L31 RS09080
gene id: 465797:I6L31_RS09080
uniprot id: A0A8F8CSH4
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

465797:I6L31 RS01175
gene id: 465797:I6L31_RS01175
uniprot id: A0A8F8CWL0
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11890
gene id: 465797:I6L31_RS11890
uniprot id: A0A8F8GKR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS05920
gene id: 465797:I6L31_RS05920
uniprot id: A0A8F8CSB3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

465797:I6L31 RS15525
gene id: 465797:I6L31_RS15525
uniprot id: A0A8F8CUD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS03945
gene id: 465797:I6L31_RS03945
uniprot id: A0A8F8CW91
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

465797:I6L31 RS15435
gene id: 465797:I6L31_RS15435
uniprot id: A0A8F8CVS9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

465797:I6L31 RS07250
gene id: 465797:I6L31_RS07250
uniprot id: A0A8F8CXD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

465797:I6L31 RS01755
gene id: 465797:I6L31_RS01755
uniprot id: A0A8F8CTB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS01600
gene id: 465797:I6L31_RS01600
uniprot id: A0A8F8CQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

465797:I6L31 RS08365
gene id: 465797:I6L31_RS08365
uniprot id: A0A8F8GN41
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS10750
gene id: 465797:I6L31_RS10750
uniprot id: A0A8F8CT06
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

465797:I6L31 RS04080
gene id: 465797:I6L31_RS04080
uniprot id: A0A8F8CR92
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS04990
gene id: 465797:I6L31_RS04990
uniprot id: A0A8F8CUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

465797:I6L31 RS12320
gene id: 465797:I6L31_RS12320
uniprot id: A0A8F8GKP7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS13490
gene id: 465797:I6L31_RS13490
uniprot id: A0A8F8CPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS00600
gene id: 465797:I6L31_RS00600
uniprot id: A0A8F8CWE4
names: Similarity
messages: Belongs to the TelA family.

465797:I6L31 RS10625
gene id: 465797:I6L31_RS10625
uniprot id: A0A8F8CSM6
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

465797:I6L31 RS03075
gene id: 465797:I6L31_RS03075
uniprot id: A0A8F8GL21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS03835
gene id: 465797:I6L31_RS03835
uniprot id: A0A8F8CR63
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

465797:I6L31 RS08790
gene id: 465797:I6L31_RS08790
uniprot id: A0A8F8CS84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

465797:I6L31 RS01750
gene id: 465797:I6L31_RS01750
uniprot id: A0A8F8CQN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

465797:I6L31 RS14775
gene id: 465797:I6L31_RS14775
uniprot id: A0A8F8CU84
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

465797:I6L31 RS03360
gene id: 465797:I6L31_RS03360
uniprot id: A0A8F8CW14
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465797:I6L31 RS03660
gene id: 465797:I6L31_RS03660
uniprot id: A0A8F8CW68
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS14455
gene id: 465797:I6L31_RS14455
uniprot id: A0A8F8GL59
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

465797:I6L31 RS09460
gene id: 465797:I6L31_RS09460
uniprot id: A0A8F8CMU4
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

465797:I6L31 RS16565
gene id: 465797:I6L31_RS16565
uniprot id: A0A8F8CTH2
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

465797:I6L31 RS12375
gene id: 465797:I6L31_RS12375
uniprot id: A0A8F8CT83
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11375
gene id: 465797:I6L31_RS11375
uniprot id: A0A8F8CT74
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

465797:I6L31 RS01140
gene id: 465797:I6L31_RS01140
uniprot id: A0A8F8CVD2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

465797:I6L31 RS01605
gene id: 465797:I6L31_RS01605
uniprot id: A0A8F8CT87
names: Similarity
messages: Belongs to the GARS family.

465797:I6L31 RS12505
gene id: 465797:I6L31_RS12505
uniprot id: A0A8F8GKQ7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

465797:I6L31 RS16085
gene id: 465797:I6L31_RS16085
uniprot id: A0A8F8CSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

465797:I6L31 RS09510
gene id: 465797:I6L31_RS09510
uniprot id: A0A8F8GMV9
names: Similarity
messages: Belongs to the VgrG protein family.

465797:I6L31 RS03010
gene id: 465797:I6L31_RS03010
uniprot id: A0A8F8GM07
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

465797:I6L31 RS04310
gene id: 465797:I6L31_RS04310
uniprot id: A0A8F8GM89
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465797:I6L31 RS02165
gene id: 465797:I6L31_RS02165
uniprot id: A0A8F8CQT1
names: Similarity
messages: Belongs to the peptidase M1 family.

465797:I6L31 RS12310
gene id: 465797:I6L31_RS12310
uniprot id: A0A8F8CRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS03820
gene id: 465797:I6L31_RS03820
uniprot id: A0A8F8GM60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

465797:I6L31 RS17445
gene id: 465797:I6L31_RS17445
uniprot id: A0A8F8GNB5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

465797:I6L31 RS14100
gene id: 465797:I6L31_RS14100
uniprot id: A0A8F8CTU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

465797:I6L31 RS03730
gene id: 465797:I6L31_RS03730
uniprot id: A0A8F8GM56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

465797:I6L31 RS14585
gene id: 465797:I6L31_RS14585
uniprot id: A0A8F8CS06
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

465797:I6L31 RS12285
gene id: 465797:I6L31_RS12285
uniprot id: A0A8F8CNP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

465797:I6L31 RS03840
gene id: 465797:I6L31_RS03840
uniprot id: A0A8F8CR65
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

465797:I6L31 RS08135
gene id: 465797:I6L31_RS08135
uniprot id: A0A8F8CXR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

465797:I6L31 RS11150
gene id: 465797:I6L31_RS11150
uniprot id: A0A8F8CQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465797:I6L31 RS09110
gene id: 465797:I6L31_RS09110
uniprot id: A0A8F8CS60
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS15800
gene id: 465797:I6L31_RS15800
uniprot id: A0A8F8GLK5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

465797:I6L31 RS17230
gene id: 465797:I6L31_RS17230
uniprot id: A0A8F8GN75
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465797:I6L31 RS16135
gene id: 465797:I6L31_RS16135
uniprot id: A0A8F8CQF2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS12100
gene id: 465797:I6L31_RS12100
uniprot id: A0A8F8CR67
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS06255
gene id: 465797:I6L31_RS06255
uniprot id: A0A8F8GMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS07690
gene id: 465797:I6L31_RS07690
uniprot id: A0A8F8CSG9
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS09405
gene id: 465797:I6L31_RS09405
uniprot id: A0A8F8GK91
names: Similarity
messages: Belongs to the Fur family.

465797:I6L31 RS09385
gene id: 465797:I6L31_RS09385
uniprot id: A0A8F8CS91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

465797:I6L31 RS10010
gene id: 465797:I6L31_RS10010
uniprot id: A0A8F8CSY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

465797:I6L31 RS04620
gene id: 465797:I6L31_RS04620
uniprot id: A0A8F8CWD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

465797:I6L31 RS15335
gene id: 465797:I6L31_RS15335
uniprot id: A0A8F8CPH7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS04015
gene id: 465797:I6L31_RS04015
uniprot id: A0A8F8CXH6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

465797:I6L31 RS14540
gene id: 465797:I6L31_RS14540
uniprot id: A0A8F8CPX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

465797:I6L31 RS09155
gene id: 465797:I6L31_RS09155
uniprot id: A0A8F8GKB5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS14530
gene id: 465797:I6L31_RS14530
uniprot id: A0A8F8GLD1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

465797:I6L31 RS02865
gene id: 465797:I6L31_RS02865
uniprot id: A0A8F8CQU4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

465797:I6L31 RS11680
gene id: 465797:I6L31_RS11680
uniprot id: A0A8F8CUQ7
names: Similarity
messages: Belongs to the transposase 8 family.

465797:I6L31 RS13750
gene id: 465797:I6L31_RS13750
uniprot id: A0A8F8CS84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

465797:I6L31 RS16160
gene id: 465797:I6L31_RS16160
uniprot id: A0A8F8CPZ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465797:I6L31 RS12925
gene id: 465797:I6L31_RS12925
uniprot id: A0A8F8GKX3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465797:I6L31 RS07935
gene id: 465797:I6L31_RS07935
uniprot id: A0A8F8CSY0
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS03500
gene id: 465797:I6L31_RS03500
uniprot id: A0A8F8CR26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

465797:I6L31 RS03920
gene id: 465797:I6L31_RS03920
uniprot id: A0A8F8CR80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

465797:I6L31 RS07620
gene id: 465797:I6L31_RS07620
uniprot id: A0A8F8CSJ8
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

465797:I6L31 RS07340
gene id: 465797:I6L31_RS07340
uniprot id: A0A8F8GMK6
names: Similarity
messages: Belongs to the YciI family.

465797:I6L31 RS14920
gene id: 465797:I6L31_RS14920
uniprot id: A0A8F8CU56
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS15720
gene id: 465797:I6L31_RS15720
uniprot id: A0A8F8GKC9
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS16585
gene id: 465797:I6L31_RS16585
uniprot id: A0A8F8CYH3
names: Similarity
messages: Belongs to the FrmR/RcnR family.

465797:I6L31 RS09005
gene id: 465797:I6L31_RS09005
uniprot id: A0A8F8CSG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

465797:I6L31 RS00525
gene id: 465797:I6L31_RS00525
uniprot id: A0A8F8CV25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

465797:I6L31 RS05275
gene id: 465797:I6L31_RS05275
uniprot id: A0A8F8GLE9
names: Similarity
messages: Belongs to the UPF0102 family.

465797:I6L31 RS13060
gene id: 465797:I6L31_RS13060
uniprot id: A0A8F8CTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS03700
gene id: 465797:I6L31_RS03700
uniprot id: A0A8F8CTY8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS03510
gene id: 465797:I6L31_RS03510
uniprot id: A0A8F8CTW8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS08760
gene id: 465797:I6L31_RS08760
uniprot id: A0A8F8CMF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

465797:I6L31 RS16580
gene id: 465797:I6L31_RS16580
uniprot id: A0A8F8CYE0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

465797:I6L31 RS14285
gene id: 465797:I6L31_RS14285
uniprot id: A0A8F8GK44
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

465797:I6L31 RS06495
gene id: 465797:I6L31_RS06495
uniprot id: A0A8F8CX02
names: Similarity
messages: Belongs to the GppA/Ppx family.

465797:I6L31 RS02915
gene id: 465797:I6L31_RS02915
uniprot id: A0A8F8GL12
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465797:I6L31 RS09345
gene id: 465797:I6L31_RS09345
uniprot id: A0A8F8GKC5
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

465797:I6L31 RS07255
gene id: 465797:I6L31_RS07255
uniprot id: A0A8F8CV44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

465797:I6L31 RS00755
gene id: 465797:I6L31_RS00755
uniprot id: A0A8F8CQC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

465797:I6L31 RS16595
gene id: 465797:I6L31_RS16595
uniprot id: A0A8F8GLE7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS04810
gene id: 465797:I6L31_RS04810
uniprot id: A0A8F8GN62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

465797:I6L31 RS08845
gene id: 465797:I6L31_RS08845
uniprot id: A0A8F8CNA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

465797:I6L31 RS04180
gene id: 465797:I6L31_RS04180
uniprot id: A0A8F8CRG1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

465797:I6L31 RS05165
gene id: 465797:I6L31_RS05165
uniprot id: A0A8F8GKI1
names: Similarity
messages: Belongs to the peptidase M16 family.

465797:I6L31 RS17740
gene id: 465797:I6L31_RS17740
uniprot id: A0A8F8CW08
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

465797:I6L31 RS14930
gene id: 465797:I6L31_RS14930
uniprot id: A0A8F8CS61
names: Similarity
messages: Belongs to the peptidase S49 family.

465797:I6L31 RS13740
gene id: 465797:I6L31_RS13740
uniprot id: A0A8F8CNZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

465797:I6L31 RS06505
gene id: 465797:I6L31_RS06505
uniprot id: A0A8F8CUV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

465797:I6L31 RS11350
gene id: 465797:I6L31_RS11350
uniprot id: A0A8F8GKJ3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

465797:I6L31 RS04225
gene id: 465797:I6L31_RS04225
uniprot id: A0A8F8GL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS04950
gene id: 465797:I6L31_RS04950
uniprot id: A0A8F8CXZ0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

465797:I6L31 RS10935
gene id: 465797:I6L31_RS10935
uniprot id: A0A8F8CT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

465797:I6L31 RS17500
gene id: 465797:I6L31_RS17500
uniprot id: A0A8F8CVX7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS02310
gene id: 465797:I6L31_RS02310
uniprot id: A0A8F8CSS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

465797:I6L31 RS01245
gene id: 465797:I6L31_RS01245
uniprot id: A0A8F8CQX4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

465797:I6L31 RS04935
gene id: 465797:I6L31_RS04935
uniprot id: A0A8F8CS09
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS12005
gene id: 465797:I6L31_RS12005
uniprot id: A0A8F8CNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

465797:I6L31 RS04135
gene id: 465797:I6L31_RS04135
uniprot id: A0A8F8GKC1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

465797:I6L31 RS14490
gene id: 465797:I6L31_RS14490
uniprot id: A0A8F8CVG3
names: Similarity
messages: Belongs to the UPF0250 family.

465797:I6L31 RS06385
gene id: 465797:I6L31_RS06385
uniprot id: A0A8F8CY85
names: Similarity
messages: Belongs to the BolA/IbaG family.

465797:I6L31 RS10720
gene id: 465797:I6L31_RS10720
uniprot id: A0A8F8GL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS08405
gene id: 465797:I6L31_RS08405
uniprot id: A0A8F8CQJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

465797:I6L31 RS12235
gene id: 465797:I6L31_RS12235
uniprot id: A0A8F8CT05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

465797:I6L31 RS04195
gene id: 465797:I6L31_RS04195
uniprot id: A0A8F8CW71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS14125
gene id: 465797:I6L31_RS14125
uniprot id: A0A8F8GK32
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS05230
gene id: 465797:I6L31_RS05230
uniprot id: A0A8F8CUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS15190
gene id: 465797:I6L31_RS15190
uniprot id: A0A8F8CU87
names: Similarity
messages: Belongs to the ArsC family.

465797:I6L31 RS17425
gene id: 465797:I6L31_RS17425
uniprot id: A0A8F8CVW6
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

465797:I6L31 RS18155
gene id: 465797:I6L31_RS18155
uniprot id: A0A8F8CVW6
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

465797:I6L31 RS17045
gene id: 465797:I6L31_RS17045
uniprot id: A0A8F8CWF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

465797:I6L31 RS05585
gene id: 465797:I6L31_RS05585
uniprot id: A0A8F8CRV9
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS16235
gene id: 465797:I6L31_RS16235
uniprot id: A0A8F8CPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS14725
gene id: 465797:I6L31_RS14725
uniprot id: A0A8F8GL74
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

465797:I6L31 RS09690
gene id: 465797:I6L31_RS09690
uniprot id: A0A8F8GIJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

465797:I6L31 RS14380
gene id: 465797:I6L31_RS14380
uniprot id: A0A8F8GL55
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

465797:I6L31 RS02680
gene id: 465797:I6L31_RS02680
uniprot id: A0A8F8CQS5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465797:I6L31 RS00545
gene id: 465797:I6L31_RS00545
uniprot id: A0A8F8GKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

465797:I6L31 RS03960
gene id: 465797:I6L31_RS03960
uniprot id: A0A8F8GM20
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS17980
gene id: 465797:I6L31_RS17980
uniprot id: A0A8F8CTA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Membrane

465797:I6L31 RS05475
gene id: 465797:I6L31_RS05475
uniprot id: A0A8F8GMF6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465797:I6L31 RS08415
gene id: 465797:I6L31_RS08415
uniprot id: A0A8F8GK73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS15570
gene id: 465797:I6L31_RS15570
uniprot id: A0A8F8CUM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

465797:I6L31 RS02460
gene id: 465797:I6L31_RS02460
uniprot id: A0A8F8CRA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS13160
gene id: 465797:I6L31_RS13160
uniprot id: A0A8F8GL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS15840
gene id: 465797:I6L31_RS15840
uniprot id: A0A8F8CPN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS08195
gene id: 465797:I6L31_RS08195
uniprot id: A0A8F8GLX2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

465797:I6L31 RS15730
gene id: 465797:I6L31_RS15730
uniprot id: A0A8F8GLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

465797:I6L31 RS03280
gene id: 465797:I6L31_RS03280
uniprot id: A0A8F8CW01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS08970
gene id: 465797:I6L31_RS08970
uniprot id: A0A8F8CQ73
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

465797:I6L31 RS08770
gene id: 465797:I6L31_RS08770
uniprot id: A0A8F8CQ30
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

465797:I6L31 RS01320
gene id: 465797:I6L31_RS01320
uniprot id: A0A8F8CQY2
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11430
gene id: 465797:I6L31_RS11430
uniprot id: A0A8F8GIT5
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

465797:I6L31 RS05645
gene id: 465797:I6L31_RS05645
uniprot id: A0A8F8GMG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS12325
gene id: 465797:I6L31_RS12325
uniprot id: A0A8F8GJS8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465797:I6L31 RS09280
gene id: 465797:I6L31_RS09280
uniprot id: A0A8F8CSJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS10155
gene id: 465797:I6L31_RS10155
uniprot id: A0A8F8CSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

465797:I6L31 RS14445
gene id: 465797:I6L31_RS14445
uniprot id: A0A8F8GK53
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

465797:I6L31 RS11230
gene id: 465797:I6L31_RS11230
uniprot id: A0A8F8CVT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

465797:I6L31 RS13845
gene id: 465797:I6L31_RS13845
uniprot id: A0A8F8CRR6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

465797:I6L31 RS03400
gene id: 465797:I6L31_RS03400
uniprot id: A0A8F8CW36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

465797:I6L31 RS10190
gene id: 465797:I6L31_RS10190
uniprot id: A0A8F8GKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

465797:I6L31 RS01035
gene id: 465797:I6L31_RS01035
uniprot id: A0A8F8GJU7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

465797:I6L31 RS08645
gene id: 465797:I6L31_RS08645
uniprot id: A0A8F8GK51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

465797:I6L31 RS16220
gene id: 465797:I6L31_RS16220
uniprot id: A0A8F8CUV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS07070
gene id: 465797:I6L31_RS07070
uniprot id: A0A8F8CYG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

465797:I6L31 RS13240
gene id: 465797:I6L31_RS13240
uniprot id: A0A8F8GJY1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

465797:I6L31 RS10665
gene id: 465797:I6L31_RS10665
uniprot id: A0A8F8CNT8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS12660
gene id: 465797:I6L31_RS12660
uniprot id: A0A8F8CTG5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

465797:I6L31 RS01515
gene id: 465797:I6L31_RS01515
uniprot id: A0A8F8CT77
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

465797:I6L31 RS07110
gene id: 465797:I6L31_RS07110
uniprot id: A0A8F8GMW5
names: Subunit
messages: Monomer.

465797:I6L31 RS14780
gene id: 465797:I6L31_RS14780
uniprot id: A0A8F8CS40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

465797:I6L31 RS08535
gene id: 465797:I6L31_RS08535
uniprot id: A0A8F8CQ00
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

465797:I6L31 RS04125
gene id: 465797:I6L31_RS04125
uniprot id: A0A8F8CWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

465797:I6L31 RS09935
gene id: 465797:I6L31_RS09935
uniprot id: A0A8F8CMR8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465797:I6L31 RS06290
gene id: 465797:I6L31_RS06290
uniprot id: A0A8F8CY73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

465797:I6L31 RS11490
gene id: 465797:I6L31_RS11490
uniprot id: A0A8F8CSX3
names: Similarity
messages: Belongs to the pirin family.

465797:I6L31 RS03095
gene id: 465797:I6L31_RS03095
uniprot id: A0A8F8CVZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

465797:I6L31 RS13070
gene id: 465797:I6L31_RS13070
uniprot id: A0A8F8GJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

465797:I6L31 RS02285
gene id: 465797:I6L31_RS02285
uniprot id: A0A8F8GKX5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

465797:I6L31 RS09680
gene id: 465797:I6L31_RS09680
uniprot id: A0A8F8CSI3
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07740
gene id: 465797:I6L31_RS07740
uniprot id: A0A8F8GMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

465797:I6L31 RS09010
gene id: 465797:I6L31_RS09010
uniprot id: A0A8F8CMH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

465797:I6L31 RS02175
gene id: 465797:I6L31_RS02175
uniprot id: A0A8F8CWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

465797:I6L31 RS16100
gene id: 465797:I6L31_RS16100
uniprot id: A0A8F8CUP9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS14940
gene id: 465797:I6L31_RS14940
uniprot id: A0A8F8CY26
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11755
gene id: 465797:I6L31_RS11755
uniprot id: A0A8F8GIV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

465797:I6L31 RS02055
gene id: 465797:I6L31_RS02055
uniprot id: A0A8F8GKW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

465797:I6L31 RS12705
gene id: 465797:I6L31_RS12705
uniprot id: A0A8F8CTL4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS03625
gene id: 465797:I6L31_RS03625
uniprot id: A0A8F8GK92
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

465797:I6L31 RS01460
gene id: 465797:I6L31_RS01460
uniprot id: A0A8F8GL29
names: Similarity
messages: Belongs to the UPF0053 family.

465797:I6L31 RS07270
gene id: 465797:I6L31_RS07270
uniprot id: A0A8F8GLR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

465797:I6L31 RS01400
gene id: 465797:I6L31_RS01400
uniprot id: A0A8F8GLR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

465797:I6L31 RS06160
gene id: 465797:I6L31_RS06160
uniprot id: A0A8F8GMQ8
names: Similarity
messages: Belongs to the transposase 8 family.

465797:I6L31 RS18225
gene id: 465797:I6L31_RS18225
uniprot id: A0A8F8CVW6
names: Function
names: Similarity
messages: Absolutely required for transposition of IS1.
messages: Belongs to the transposase 27 family.

465797:I6L31 RS04420
gene id: 465797:I6L31_RS04420
uniprot id: A0A8F8CWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

465797:I6L31 RS14745
gene id: 465797:I6L31_RS14745
uniprot id: A0A8F8CPB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

465797:I6L31 RS10845
gene id: 465797:I6L31_RS10845
uniprot id: A0A8F8CNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

465797:I6L31 RS12395
gene id: 465797:I6L31_RS12395
uniprot id: A0A8F8CRC1
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

465797:I6L31 RS15300
gene id: 465797:I6L31_RS15300
uniprot id: A0A8F8GKA4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS11920
gene id: 465797:I6L31_RS11920
uniprot id: A0A8F8CNK7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465797:I6L31 RS04460
gene id: 465797:I6L31_RS04460
uniprot id: A0A8F8CU86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

465797:I6L31 RS01205
gene id: 465797:I6L31_RS01205
uniprot id: A0A8F8GJV5
names: Similarity
messages: Belongs to the SurE nucleotidase family.

465797:I6L31 RS16090
gene id: 465797:I6L31_RS16090
uniprot id: A0A8F8CW12
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

465797:I6L31 RS03225
gene id: 465797:I6L31_RS03225
uniprot id: A0A8F8GL31
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

465797:I6L31 RS14325
gene id: 465797:I6L31_RS14325
uniprot id: A0A8F8CP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS13095
gene id: 465797:I6L31_RS13095
uniprot id: A0A8F8CPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

465797:I6L31 RS11390
gene id: 465797:I6L31_RS11390
uniprot id: A0A8F8CNF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS07030
gene id: 465797:I6L31_RS07030
uniprot id: A0A8F8GMW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

465797:I6L31 RS08890
gene id: 465797:I6L31_RS08890
uniprot id: A0A8F8CS94
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

465797:I6L31 RS05930
gene id: 465797:I6L31_RS05930
uniprot id: A0A8F8CRV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465797:I6L31 RS13960
gene id: 465797:I6L31_RS13960
uniprot id: A0A8F8GJ81
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS06935
gene id: 465797:I6L31_RS06935
uniprot id: A0A8F8GMP0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465797:I6L31 RS02640
gene id: 465797:I6L31_RS02640
uniprot id: A0A8F8CTL2
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS14265
gene id: 465797:I6L31_RS14265
uniprot id: A0A8F8CRY5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS14295
gene id: 465797:I6L31_RS14295
uniprot id: A0A8F8GL50
names: Similarity
messages: Belongs to the TPP enzyme family.

465797:I6L31 RS00410
gene id: 465797:I6L31_RS00410
uniprot id: A0A8F8CQ18
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS01090
gene id: 465797:I6L31_RS01090
uniprot id: A0A8F8CWJ9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

465797:I6L31 RS13375
gene id: 465797:I6L31_RS13375
uniprot id: A0A8F8GKZ6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS01255
gene id: 465797:I6L31_RS01255
uniprot id: A0A8F8CQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

465797:I6L31 RS03005
gene id: 465797:I6L31_RS03005
uniprot id: A0A8F8GM75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

465797:I6L31 RS09050
gene id: 465797:I6L31_RS09050
uniprot id: A0A8F8GIG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

465797:I6L31 RS08140
gene id: 465797:I6L31_RS08140
uniprot id: A0A8F8CSL9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

465797:I6L31 RS06470
gene id: 465797:I6L31_RS06470
uniprot id: A0A8F8CS14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

465797:I6L31 RS10960
gene id: 465797:I6L31_RS10960
uniprot id: A0A8F8CU94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

465797:I6L31 RS10080
gene id: 465797:I6L31_RS10080
uniprot id: A0A8F8CSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

465797:I6L31 RS15510
gene id: 465797:I6L31_RS15510
uniprot id: A0A8F8CPR6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465797:I6L31 RS13110
gene id: 465797:I6L31_RS13110
uniprot id: A0A8F8CNS5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465797:I6L31 RS02210
gene id: 465797:I6L31_RS02210
uniprot id: A0A8F8GM32
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

465797:I6L31 RS02625
gene id: 465797:I6L31_RS02625
uniprot id: A0A8F8CX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

465797:I6L31 RS16140
gene id: 465797:I6L31_RS16140
uniprot id: A0A8F8CUU7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

465797:I6L31 RS04910
gene id: 465797:I6L31_RS04910
uniprot id: A0A8F8GKG8
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

465797:I6L31 RS16045
gene id: 465797:I6L31_RS16045
uniprot id: A0A8F8GKE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS14485
gene id: 465797:I6L31_RS14485
uniprot id: A0A8F8CRZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

465797:I6L31 RS05200
gene id: 465797:I6L31_RS05200
uniprot id: A0A8F8CRM5
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

465797:I6L31 RS09660
gene id: 465797:I6L31_RS09660
uniprot id: A0A8F8CMW2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

465797:I6L31 RS08710
gene id: 465797:I6L31_RS08710
uniprot id: A0A8F8CQ45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

465797:I6L31 RS04890
gene id: 465797:I6L31_RS04890
uniprot id: A0A8F8CWG3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465797:I6L31 RS04970
gene id: 465797:I6L31_RS04970
uniprot id: A0A8F8CXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

465797:I6L31 RS10600
gene id: 465797:I6L31_RS10600
uniprot id: A0A8F8CMZ8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS14885
gene id: 465797:I6L31_RS14885
uniprot id: A0A8F8CQ16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS03590
gene id: 465797:I6L31_RS03590
uniprot id: A0A8F8CR36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

465797:I6L31 RS09845
gene id: 465797:I6L31_RS09845
uniprot id: A0A8F8CMQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465797:I6L31 RS01485
gene id: 465797:I6L31_RS01485
uniprot id: A0A8F8CR00
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

465797:I6L31 RS08265
gene id: 465797:I6L31_RS08265
uniprot id: A0A8F8GL13
names: Similarity
messages: Belongs to the LOG family.

465797:I6L31 RS01170
gene id: 465797:I6L31_RS01170
uniprot id: A0A8F8CVJ6
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS06770
gene id: 465797:I6L31_RS06770
uniprot id: A0A8F8GMU4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

465797:I6L31 RS08955
gene id: 465797:I6L31_RS08955
uniprot id: A0A8F8CTM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

465797:I6L31 RS13595
gene id: 465797:I6L31_RS13595
uniprot id: A0A8F8CP40
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

465797:I6L31 RS11360
gene id: 465797:I6L31_RS11360
uniprot id: A0A8F8GKU4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

465797:I6L31 RS12695
gene id: 465797:I6L31_RS12695
uniprot id: A0A8F8CPD7
names: Similarity
messages: Belongs to the catalase family.

465797:I6L31 RS14390
gene id: 465797:I6L31_RS14390
uniprot id: A0A8F8CU71
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

465797:I6L31 RS06320
gene id: 465797:I6L31_RS06320
uniprot id: A0A8F8GME6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

465797:I6L31 RS02435
gene id: 465797:I6L31_RS02435
uniprot id: A0A8F8GK24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

465797:I6L31 RS14405
gene id: 465797:I6L31_RS14405
uniprot id: A0A8F8CPD8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

465797:I6L31 RS10205
gene id: 465797:I6L31_RS10205
uniprot id: A0A8F8CMV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

465797:I6L31 RS10060
gene id: 465797:I6L31_RS10060
uniprot id: A0A8F8CMZ7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS06605
gene id: 465797:I6L31_RS06605
uniprot id: A0A8F8GMG4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

465797:I6L31 RS04150
gene id: 465797:I6L31_RS04150
uniprot id: A0A8F8GME3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

465797:I6L31 RS07505
gene id: 465797:I6L31_RS07505
uniprot id: A0A8F8GLS9
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

465797:I6L31 RS10135
gene id: 465797:I6L31_RS10135
uniprot id: A0A8F8CN07
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

465797:I6L31 RS10235
gene id: 465797:I6L31_RS10235
uniprot id: A0A8F8CSH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

465797:I6L31 RS11740
gene id: 465797:I6L31_RS11740
uniprot id: A0A8F8CT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

465797:I6L31 RS01675
gene id: 465797:I6L31_RS01675
uniprot id: A0A8F8CQM2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

465797:I6L31 RS02115
gene id: 465797:I6L31_RS02115
uniprot id: A0A8F8CTE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465797:I6L31 RS11560
gene id: 465797:I6L31_RS11560
uniprot id: A0A8F8CR07
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

465797:I6L31 RS08060
gene id: 465797:I6L31_RS08060
uniprot id: A0A8F8CSL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

465797:I6L31 RS00655
gene id: 465797:I6L31_RS00655
uniprot id: A0A8F8CQR8
names: Similarity
messages: Belongs to the GSP E family.

465797:I6L31 RS02060
gene id: 465797:I6L31_RS02060
uniprot id: A0A8F8GM23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

465797:I6L31 RS08180
gene id: 465797:I6L31_RS08180
uniprot id: A0A8F8CVG0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

465797:I6L31 RS15865
gene id: 465797:I6L31_RS15865
uniprot id: A0A8F8CUH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

465797:I6L31 RS17925
gene id: 465797:I6L31_RS17925
uniprot id: A0A8F8GLC2
names: Similarity
messages: Belongs to the CopC family.

465797:I6L31 RS08500
gene id: 465797:I6L31_RS08500
uniprot id: A0A8F8CSX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465797:I6L31 RS11130
gene id: 465797:I6L31_RS11130
uniprot id: A0A8F8CT44
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
messages: Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.

465797:I6L31 RS03025
gene id: 465797:I6L31_RS03025
uniprot id: A0A8F8CQW4
names: Similarity
messages: Belongs to the FrmR/RcnR family.

465797:I6L31 RS06395
gene id: 465797:I6L31_RS06395
uniprot id: A0A8F8CX32
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

465797:I6L31 RS01440
gene id: 465797:I6L31_RS01440
uniprot id: A0A8F8CV80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

465797:I6L31 RS06775
gene id: 465797:I6L31_RS06775
uniprot id: A0A8F8GMN0
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

465797:I6L31 RS03385
gene id: 465797:I6L31_RS03385
uniprot id: A0A8F8GMA0
names: Similarity
messages: Belongs to the glutamate synthase family.

465797:I6L31 RS08575
gene id: 465797:I6L31_RS08575
uniprot id: A0A8F8GKD2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

465797:I6L31 RS10125
gene id: 465797:I6L31_RS10125
uniprot id: A0A8F8CMU0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

465797:I6L31 RS10980
gene id: 465797:I6L31_RS10980
uniprot id: A0A8F8GIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

465797:I6L31 RS07290
gene id: 465797:I6L31_RS07290
uniprot id: A0A8F8CXG2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

465797:I6L31 RS09525
gene id: 465797:I6L31_RS09525
uniprot id: A0A8F8GII3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

465797:I6L31 RS07040
gene id: 465797:I6L31_RS07040
uniprot id: A0A8F8CSN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

465797:I6L31 RS08590
gene id: 465797:I6L31_RS08590
uniprot id: A0A8F8CSB8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

465797:I6L31 RS01900
gene id: 465797:I6L31_RS01900
uniprot id: A0A8F8CQJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

465797:I6L31 RS02180
gene id: 465797:I6L31_RS02180
uniprot id: A0A8F8CVG2
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS01160
gene id: 465797:I6L31_RS01160
uniprot id: A0A8F8CQH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465797:I6L31 RS14840
gene id: 465797:I6L31_RS14840
uniprot id: A0A8F8CVK9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

465797:I6L31 RS04120
gene id: 465797:I6L31_RS04120
uniprot id: A0A8F8CW62
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

465797:I6L31 RS14385
gene id: 465797:I6L31_RS14385
uniprot id: A0A8F8CPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS06710
gene id: 465797:I6L31_RS06710
uniprot id: A0A8F8CX82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS06675
gene id: 465797:I6L31_RS06675
uniprot id: A0A8F8CUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS14550
gene id: 465797:I6L31_RS14550
uniprot id: A0A8F8CP95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

465797:I6L31 RS04995
gene id: 465797:I6L31_RS04995
uniprot id: A0A8F8GKH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

465797:I6L31 RS10210
gene id: 465797:I6L31_RS10210
uniprot id: A0A8F8CMV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

465797:I6L31 RS15375
gene id: 465797:I6L31_RS15375
uniprot id: A0A8F8GJG5
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

465797:I6L31 RS17165
gene id: 465797:I6L31_RS17165
uniprot id: A0A8F8GNK3
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07200
gene id: 465797:I6L31_RS07200
uniprot id: A0A8F8GMQ5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

465797:I6L31 RS01065
gene id: 465797:I6L31_RS01065
uniprot id: A0A8F8CVB9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

465797:I6L31 RS12610
gene id: 465797:I6L31_RS12610
uniprot id: A0A8F8CPC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS03495
gene id: 465797:I6L31_RS03495
uniprot id: A0A8F8CR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

465797:I6L31 RS17890
gene id: 465797:I6L31_RS17890
uniprot id: A0A8F8CTC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

465797:I6L31 RS04190
gene id: 465797:I6L31_RS04190
uniprot id: A0A8F8CXJ6
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

465797:I6L31 RS08160
gene id: 465797:I6L31_RS08160
uniprot id: A0A8F8CVF4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

465797:I6L31 RS10305
gene id: 465797:I6L31_RS10305
uniprot id: A0A8F8CN29
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

465797:I6L31 RS09670
gene id: 465797:I6L31_RS09670
uniprot id: A0A8F8CTV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

465797:I6L31 RS03230
gene id: 465797:I6L31_RS03230
uniprot id: A0A8F8GM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

465797:I6L31 RS14545
gene id: 465797:I6L31_RS14545
uniprot id: A0A8F8CU92
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

465797:I6L31 RS06720
gene id: 465797:I6L31_RS06720
uniprot id: A0A8F8CS42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS09235
gene id: 465797:I6L31_RS09235
uniprot id: A0A8F8CSD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

465797:I6L31 RS03925
gene id: 465797:I6L31_RS03925
uniprot id: A0A8F8CRC6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

465797:I6L31 RS16590
gene id: 465797:I6L31_RS16590
uniprot id: A0A8F8CW83
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

465797:I6L31 RS00760
gene id: 465797:I6L31_RS00760
uniprot id: A0A8F8CSY9
names: Similarity
messages: Belongs to the aspartokinase family.

465797:I6L31 RS03885
gene id: 465797:I6L31_RS03885
uniprot id: A0A8F8GL70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

465797:I6L31 RS15615
gene id: 465797:I6L31_RS15615
uniprot id: A0A8F8GJI0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

465797:I6L31 RS04115
gene id: 465797:I6L31_RS04115
uniprot id: A0A8F8CXI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

465797:I6L31 RS09505
gene id: 465797:I6L31_RS09505
uniprot id: A0A8F8CSG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

465797:I6L31 RS13050
gene id: 465797:I6L31_RS13050
uniprot id: A0A8F8CTG6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

465797:I6L31 RS04025
gene id: 465797:I6L31_RS04025
uniprot id: A0A8F8CWA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

465797:I6L31 RS09550
gene id: 465797:I6L31_RS09550
uniprot id: A0A8F8GKD5
names: Similarity
messages: Belongs to the pirin family.

465797:I6L31 RS02520
gene id: 465797:I6L31_RS02520
uniprot id: A0A8F8CQW7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

465797:I6L31 RS04710
gene id: 465797:I6L31_RS04710
uniprot id: A0A8F8CUB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465797:I6L31 RS00715
gene id: 465797:I6L31_RS00715
uniprot id: A0A8F8GLI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS04430
gene id: 465797:I6L31_RS04430
uniprot id: A0A8F8CRE1
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

465797:I6L31 RS12575
gene id: 465797:I6L31_RS12575
uniprot id: A0A8F8CTF5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

465797:I6L31 RS05385
gene id: 465797:I6L31_RS05385
uniprot id: A0A8F8CXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

465797:I6L31 RS03105
gene id: 465797:I6L31_RS03105
uniprot id: A0A8F8CQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

465797:I6L31 RS12490
gene id: 465797:I6L31_RS12490
uniprot id: A0A8F8CRD2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

465797:I6L31 RS10710
gene id: 465797:I6L31_RS10710
uniprot id: A0A8F8CQR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

465797:I6L31 RS02030
gene id: 465797:I6L31_RS02030
uniprot id: A0A8F8CVJ2
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

465797:I6L31 RS11015
gene id: 465797:I6L31_RS11015
uniprot id: A0A8F8CNX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

465797:I6L31 RS05465
gene id: 465797:I6L31_RS05465
uniprot id: A0A8F8GML7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07870
gene id: 465797:I6L31_RS07870
uniprot id: A0A8F8CSI7
names: Similarity
messages: Belongs to the PhoH family.

465797:I6L31 RS15155
gene id: 465797:I6L31_RS15155
uniprot id: A0A8F8CQ42
names: Similarity
messages: Belongs to the FeoA family.

465797:I6L31 RS18115
gene id: 465797:I6L31_RS18115
uniprot id: A0A8F8GLD2
names: Function
messages: Involved in the transposition of the insertion sequence.

465797:I6L31 RS14495
gene id: 465797:I6L31_RS14495
uniprot id: A0A8F8CU05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

465797:I6L31 RS14560
gene id: 465797:I6L31_RS14560
uniprot id: A0A8F8CPF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

465797:I6L31 RS01280
gene id: 465797:I6L31_RS01280
uniprot id: A0A8F8CV60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

465797:I6L31 RS03440
gene id: 465797:I6L31_RS03440
uniprot id: A0A8F8CTW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

465797:I6L31 RS05060
gene id: 465797:I6L31_RS05060
uniprot id: A0A8F8CWI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

465797:I6L31 RS02400
gene id: 465797:I6L31_RS02400
uniprot id: A0A8F8CQP6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

465797:I6L31 RS07315
gene id: 465797:I6L31_RS07315
uniprot id: A0A8F8CYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

465797:I6L31 RS13025
gene id: 465797:I6L31_RS13025
uniprot id: A0A8F8CNS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

465797:I6L31 RS14605
gene id: 465797:I6L31_RS14605
uniprot id: A0A8F8CU64
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

465797:I6L31 RS15115
gene id: 465797:I6L31_RS15115
uniprot id: A0A8F8CS78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

465797:I6L31 RS06860
gene id: 465797:I6L31_RS06860
uniprot id: A0A8F8CXA8
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

465797:I6L31 RS12975
gene id: 465797:I6L31_RS12975
uniprot id: A0A8F8CRJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS00780
gene id: 465797:I6L31_RS00780
uniprot id: A0A8F8CV53
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

465797:I6L31 RS14010
gene id: 465797:I6L31_RS14010
uniprot id: A0A8F8CRU1
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS03120
gene id: 465797:I6L31_RS03120
uniprot id: A0A8F8CX76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

465797:I6L31 RS01365
gene id: 465797:I6L31_RS01365
uniprot id: A0A8F8CVJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS09015
gene id: 465797:I6L31_RS09015
uniprot id: A0A8F8CMH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

465797:I6L31 RS12990
gene id: 465797:I6L31_RS12990
uniprot id: A0A8F8GKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

465797:I6L31 RS03070
gene id: 465797:I6L31_RS03070
uniprot id: A0A8F8GLW5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS12360
gene id: 465797:I6L31_RS12360
uniprot id: A0A8F8CNQ4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

465797:I6L31 RS13780
gene id: 465797:I6L31_RS13780
uniprot id: A0A8F8CTV5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

465797:I6L31 RS12455
gene id: 465797:I6L31_RS12455
uniprot id: A0A8F8CNK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

465797:I6L31 RS13640
gene id: 465797:I6L31_RS13640
uniprot id: A0A8F8GK01
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

465797:I6L31 RS07715
gene id: 465797:I6L31_RS07715
uniprot id: A0A8F8CXZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

465797:I6L31 RS16980
gene id: 465797:I6L31_RS16980
uniprot id: A0A8F8CYN0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

465797:I6L31 RS02665
gene id: 465797:I6L31_RS02665
uniprot id: A0A8F8GLY7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS15620
gene id: 465797:I6L31_RS15620
uniprot id: A0A8F8GL88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

465797:I6L31 RS03770
gene id: 465797:I6L31_RS03770
uniprot id: A0A8F8CU00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

465797:I6L31 RS07875
gene id: 465797:I6L31_RS07875
uniprot id: A0A8F8CSI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

465797:I6L31 RS05600
gene id: 465797:I6L31_RS05600
uniprot id: A0A8F8CXZ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS08670
gene id: 465797:I6L31_RS08670
uniprot id: A0A8F8CSC7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

465797:I6L31 RS12050
gene id: 465797:I6L31_RS12050
uniprot id: A0A8F8GKN1
names: Similarity
messages: Belongs to the glutamate synthase family.

465797:I6L31 RS06845
gene id: 465797:I6L31_RS06845
uniprot id: A0A8F8GMV0
names: Similarity
messages: Belongs to the FrmR/RcnR family.

465797:I6L31 RS02325
gene id: 465797:I6L31_RS02325
uniprot id: A0A8F8CQN6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

465797:I6L31 RS01845
gene id: 465797:I6L31_RS01845
uniprot id: A0A8F8CWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

465797:I6L31 RS05295
gene id: 465797:I6L31_RS05295
uniprot id: A0A8F8CWR4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

465797:I6L31 RS10955
gene id: 465797:I6L31_RS10955
uniprot id: A0A8F8CQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

465797:I6L31 RS04965
gene id: 465797:I6L31_RS04965
uniprot id: A0A8F8CUD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS02920
gene id: 465797:I6L31_RS02920
uniprot id: A0A8F8GM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

465797:I6L31 RS02710
gene id: 465797:I6L31_RS02710
uniprot id: A0A8F8CSV9
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS17170
gene id: 465797:I6L31_RS17170
uniprot id: A0A8F8GND8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

465797:I6L31 RS10325
gene id: 465797:I6L31_RS10325
uniprot id: A0A8F8CSP7
names: Similarity
messages: Belongs to the allantoicase family.

465797:I6L31 RS00440
gene id: 465797:I6L31_RS00440
uniprot id: A0A8F8CV16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

465797:I6L31 RS17185
gene id: 465797:I6L31_RS17185
uniprot id: A0A8F8CTM7
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

465797:I6L31 RS10200
gene id: 465797:I6L31_RS10200
uniprot id: A0A8F8CST8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

465797:I6L31 RS11780
gene id: 465797:I6L31_RS11780
uniprot id: A0A8F8GKW9
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS15770
gene id: 465797:I6L31_RS15770
uniprot id: A0A8F8CUG0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

465797:I6L31 RS03490
gene id: 465797:I6L31_RS03490
uniprot id: A0A8F8CW45
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS04470
gene id: 465797:I6L31_RS04470
uniprot id: A0A8F8GM48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

465797:I6L31 RS03605
gene id: 465797:I6L31_RS03605
uniprot id: A0A8F8CXC8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08925
gene id: 465797:I6L31_RS08925
uniprot id: A0A8F8CNB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

465797:I6L31 RS09590
gene id: 465797:I6L31_RS09590
uniprot id: A0A8F8CSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS05285
gene id: 465797:I6L31_RS05285
uniprot id: A0A8F8GME7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

465797:I6L31 RS08905
gene id: 465797:I6L31_RS08905
uniprot id: A0A8F8GK64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

465797:I6L31 RS01590
gene id: 465797:I6L31_RS01590
uniprot id: A0A8F8CQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465797:I6L31 RS10245
gene id: 465797:I6L31_RS10245
uniprot id: A0A8F8CSN8
names: Similarity
messages: Belongs to the ArsC family.

465797:I6L31 RS13675
gene id: 465797:I6L31_RS13675
uniprot id: A0A8F8CP53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

465797:I6L31 RS17220
gene id: 465797:I6L31_RS17220
uniprot id: A0A8F8CWG7
names: Similarity
messages: Belongs to the ArsC family.

465797:I6L31 RS08915
gene id: 465797:I6L31_RS08915
uniprot id: A0A8F8GKF3
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

465797:I6L31 RS07335
gene id: 465797:I6L31_RS07335
uniprot id: A0A8F8GKV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

465797:I6L31 RS04305
gene id: 465797:I6L31_RS04305
uniprot id: A0A8F8GMF2
names: Similarity
messages: Belongs to the peptidase S11 family.

465797:I6L31 RS16230
gene id: 465797:I6L31_RS16230
uniprot id: A0A8F8CPT8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08165
gene id: 465797:I6L31_RS08165
uniprot id: A0A8F8CYV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

465797:I6L31 RS12630
gene id: 465797:I6L31_RS12630
uniprot id: A0A8F8CNT4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS15890
gene id: 465797:I6L31_RS15890
uniprot id: A0A8F8GKD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

465797:I6L31 RS02595
gene id: 465797:I6L31_RS02595
uniprot id: A0A8F8CRB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS08185
gene id: 465797:I6L31_RS08185
uniprot id: A0A8F8GL08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

465797:I6L31 RS13745
gene id: 465797:I6L31_RS13745
uniprot id: A0A8F8CNZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

465797:I6L31 RS14280
gene id: 465797:I6L31_RS14280
uniprot id: A0A8F8GL10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS14395
gene id: 465797:I6L31_RS14395
uniprot id: A0A8F8CP79
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

465797:I6L31 RS11470
gene id: 465797:I6L31_RS11470
uniprot id: A0A8F8CN95
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS04550
gene id: 465797:I6L31_RS04550
uniprot id: A0A8F8CU95
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

465797:I6L31 RS06570
gene id: 465797:I6L31_RS06570
uniprot id: A0A8F8CUW2
names: Similarity
messages: Belongs to the GST superfamily.

465797:I6L31 RS09225
gene id: 465797:I6L31_RS09225
uniprot id: A0A8F8CTQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS05415
gene id: 465797:I6L31_RS05415
uniprot id: A0A8F8CUI4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

465797:I6L31 RS08225
gene id: 465797:I6L31_RS08225
uniprot id: A0A8F8CSN3
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS14050
gene id: 465797:I6L31_RS14050
uniprot id: A0A8F8GK27
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

465797:I6L31 RS09245
gene id: 465797:I6L31_RS09245
uniprot id: A0A8F8GIG9
names: Similarity
messages: Belongs to the DprA/Smf family.

465797:I6L31 RS13075
gene id: 465797:I6L31_RS13075
uniprot id: A0A8F8GKU1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

465797:I6L31 RS14090
gene id: 465797:I6L31_RS14090
uniprot id: A0A8F8CRV1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS00710
gene id: 465797:I6L31_RS00710
uniprot id: A0A8F8GJS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

465797:I6L31 RS02565
gene id: 465797:I6L31_RS02565
uniprot id: A0A8F8CTK1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

465797:I6L31 RS04380
gene id: 465797:I6L31_RS04380
uniprot id: A0A8F8GKD6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS07545
gene id: 465797:I6L31_RS07545
uniprot id: A0A8F8CSJ1
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS06330
gene id: 465797:I6L31_RS06330
uniprot id: A0A8F8GLK9
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

465797:I6L31 RS13685
gene id: 465797:I6L31_RS13685
uniprot id: A0A8F8CV59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

465797:I6L31 RS02345
gene id: 465797:I6L31_RS02345
uniprot id: A0A8F8CVI1
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

465797:I6L31 RS06475
gene id: 465797:I6L31_RS06475
uniprot id: A0A8F8CS10
names: Similarity
messages: Belongs to the YggT family.

465797:I6L31 RS00785
gene id: 465797:I6L31_RS00785
uniprot id: A0A8F8CSZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

465797:I6L31 RS04075
gene id: 465797:I6L31_RS04075
uniprot id: A0A8F8CWB5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS05235
gene id: 465797:I6L31_RS05235
uniprot id: A0A8F8CXV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465797:I6L31 RS05755
gene id: 465797:I6L31_RS05755
uniprot id: A0A8F8CRT5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

465797:I6L31 RS10770
gene id: 465797:I6L31_RS10770
uniprot id: A0A8F8CQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

465797:I6L31 RS08885
gene id: 465797:I6L31_RS08885
uniprot id: A0A8F8CS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

465797:I6L31 RS10985
gene id: 465797:I6L31_RS10985
uniprot id: A0A8F8GKH5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

465797:I6L31 RS02585
gene id: 465797:I6L31_RS02585
uniprot id: A0A8F8GM52
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07400
gene id: 465797:I6L31_RS07400
uniprot id: A0A8F8CXF4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

465797:I6L31 RS06635
gene id: 465797:I6L31_RS06635
uniprot id: A0A8F8CX72
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS16265
gene id: 465797:I6L31_RS16265
uniprot id: A0A8F8CUM4
names: Similarity
messages: Belongs to the TrpC family.

465797:I6L31 RS13720
gene id: 465797:I6L31_RS13720
uniprot id: A0A8F8GL82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

465797:I6L31 RS01375
gene id: 465797:I6L31_RS01375
uniprot id: A0A8F8CT60
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

465797:I6L31 RS01080
gene id: 465797:I6L31_RS01080
uniprot id: A0A8F8CQG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS05840
gene id: 465797:I6L31_RS05840
uniprot id: A0A8F8CRU4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

465797:I6L31 RS12295
gene id: 465797:I6L31_RS12295
uniprot id: A0A8F8CUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

465797:I6L31 RS04690
gene id: 465797:I6L31_RS04690
uniprot id: A0A8F8CUA1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

465797:I6L31 RS04275
gene id: 465797:I6L31_RS04275
uniprot id: A0A8F8CW84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

465797:I6L31 RS06790
gene id: 465797:I6L31_RS06790
uniprot id: A0A8F8CS53
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

465797:I6L31 RS10650
gene id: 465797:I6L31_RS10650
uniprot id: A0A8F8GJI7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465797:I6L31 RS00540
gene id: 465797:I6L31_RS00540
uniprot id: A0A8F8GLH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

465797:I6L31 RS07300
gene id: 465797:I6L31_RS07300
uniprot id: A0A8F8CSB4
names: Cofactor
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.

465797:I6L31 RS06800
gene id: 465797:I6L31_RS06800
uniprot id: A0A8F8CS96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

465797:I6L31 RS12280
gene id: 465797:I6L31_RS12280
uniprot id: A0A8F8CNI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

465797:I6L31 RS09395
gene id: 465797:I6L31_RS09395
uniprot id: A0A8F8CQC3
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS13580
gene id: 465797:I6L31_RS13580
uniprot id: A0A8F8CNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

465797:I6L31 RS15660
gene id: 465797:I6L31_RS15660
uniprot id: A0A8F8CPM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS08325
gene id: 465797:I6L31_RS08325
uniprot id: A0A8F8CYW5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

465797:I6L31 RS03815
gene id: 465797:I6L31_RS03815
uniprot id: A0A8F8GMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS04725
gene id: 465797:I6L31_RS04725
uniprot id: A0A8F8GLC0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS15360
gene id: 465797:I6L31_RS15360
uniprot id: A0A8F8CUA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

465797:I6L31 RS01325
gene id: 465797:I6L31_RS01325
uniprot id: A0A8F8CVE7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

465797:I6L31 RS09925
gene id: 465797:I6L31_RS09925
uniprot id: A0A8F8CNL0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS05705
gene id: 465797:I6L31_RS05705
uniprot id: A0A8F8CWQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS12970
gene id: 465797:I6L31_RS12970
uniprot id: A0A8F8CTK8
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

465797:I6L31 RS00765
gene id: 465797:I6L31_RS00765
uniprot id: A0A8F8CT33
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

465797:I6L31 RS08215
gene id: 465797:I6L31_RS08215
uniprot id: A0A8F8CXS4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

465797:I6L31 RS13380
gene id: 465797:I6L31_RS13380
uniprot id: A0A8F8CPL0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

465797:I6L31 RS10850
gene id: 465797:I6L31_RS10850
uniprot id: A0A8F8CT14
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

465797:I6L31 RS13910
gene id: 465797:I6L31_RS13910
uniprot id: A0A8F8CU10
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS07595
gene id: 465797:I6L31_RS07595
uniprot id: A0A8F8GMT2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS18070
gene id: 465797:I6L31_RS18070
uniprot id: A0A8F8CTB3
names: Similarity
messages: Belongs to the GcvT family.

465797:I6L31 RS00475
gene id: 465797:I6L31_RS00475
uniprot id: A0A8F8CQQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

465797:I6L31 RS08650
gene id: 465797:I6L31_RS08650
uniprot id: A0A8F8GJ79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

465797:I6L31 RS04480
gene id: 465797:I6L31_RS04480
uniprot id: A0A8F8GMG2
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS13765
gene id: 465797:I6L31_RS13765
uniprot id: A0A8F8CV68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

465797:I6L31 RS03020
gene id: 465797:I6L31_RS03020
uniprot id: A0A8F8CVY5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

465797:I6L31 RS10240
gene id: 465797:I6L31_RS10240
uniprot id: A0A8F8CXY5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

465797:I6L31 RS10500
gene id: 465797:I6L31_RS10500
uniprot id: A0A8F8GKP2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS10515
gene id: 465797:I6L31_RS10515
uniprot id: A0A8F8CSX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465797:I6L31 RS11020
gene id: 465797:I6L31_RS11020
uniprot id: A0A8F8CT32
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

465797:I6L31 RS01775
gene id: 465797:I6L31_RS01775
uniprot id: A0A8F8CTB0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

465797:I6L31 RS04610
gene id: 465797:I6L31_RS04610
uniprot id: A0A8F8CU93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

465797:I6L31 RS13040
gene id: 465797:I6L31_RS13040
uniprot id: A0A8F8CRH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

465797:I6L31 RS06910
gene id: 465797:I6L31_RS06910
uniprot id: A0A8F8GKT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

465797:I6L31 RS02570
gene id: 465797:I6L31_RS02570
uniprot id: A0A8F8GK28
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

465797:I6L31 RS04200
gene id: 465797:I6L31_RS04200
uniprot id: A0A8F8CWC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

465797:I6L31 RS12750
gene id: 465797:I6L31_RS12750
uniprot id: A0A8F8GJ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

465797:I6L31 RS10420
gene id: 465797:I6L31_RS10420
uniprot id: A0A8F8GJH2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS10480
gene id: 465797:I6L31_RS10480
uniprot id: A0A8F8CQN5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

465797:I6L31 RS01310
gene id: 465797:I6L31_RS01310
uniprot id: A0A8F8GLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

465797:I6L31 RS17160
gene id: 465797:I6L31_RS17160
uniprot id: A0A8F8GMF0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

465797:I6L31 RS06545
gene id: 465797:I6L31_RS06545
uniprot id: A0A8F8CX62
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

465797:I6L31 RS01275
gene id: 465797:I6L31_RS01275
uniprot id: A0A8F8CWL9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

465797:I6L31 RS01995
gene id: 465797:I6L31_RS01995
uniprot id: A0A8F8CVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

465797:I6L31 RS17030
gene id: 465797:I6L31_RS17030
uniprot id: A0A8F8CTK5
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS05825
gene id: 465797:I6L31_RS05825
uniprot id: A0A8F8CSA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

465797:I6L31 RS17190
gene id: 465797:I6L31_RS17190
uniprot id: A0A8F8CTM6
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

465797:I6L31 RS11590
gene id: 465797:I6L31_RS11590
uniprot id: A0A8F8GKK8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

465797:I6L31 RS01135
gene id: 465797:I6L31_RS01135
uniprot id: A0A8F8CQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

465797:I6L31 RS14695
gene id: 465797:I6L31_RS14695
uniprot id: A0A8F8CT65
names: Cofactor
messages: Can also use Mn(2+) ion.

465797:I6L31 RS14510
gene id: 465797:I6L31_RS14510
uniprot id: A0A8F8GJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

465797:I6L31 RS11860
gene id: 465797:I6L31_RS11860
uniprot id: A0A8F8CT76
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

465797:I6L31 RS05370
gene id: 465797:I6L31_RS05370
uniprot id: A0A8F8GLF4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

465797:I6L31 RS12090
gene id: 465797:I6L31_RS12090
uniprot id: A0A8F8CNG5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08145
gene id: 465797:I6L31_RS08145
uniprot id: A0A8F8CSM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

465797:I6L31 RS14770
gene id: 465797:I6L31_RS14770
uniprot id: A0A8F8CU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS08115
gene id: 465797:I6L31_RS08115
uniprot id: A0A8F8GLW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

465797:I6L31 RS07295
gene id: 465797:I6L31_RS07295
uniprot id: A0A8F8CSB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

465797:I6L31 RS15355
gene id: 465797:I6L31_RS15355
uniprot id: A0A8F8CVR8
names: Similarity
messages: Belongs to the pirin family.

465797:I6L31 RS15960
gene id: 465797:I6L31_RS15960
uniprot id: A0A8F8GLA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

465797:I6L31 RS00770
gene id: 465797:I6L31_RS00770
uniprot id: A0A8F8CWG5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

465797:I6L31 RS13690
gene id: 465797:I6L31_RS13690
uniprot id: A0A8F8CTN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

465797:I6L31 RS07280
gene id: 465797:I6L31_RS07280
uniprot id: A0A8F8GMR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

465797:I6L31 RS03255
gene id: 465797:I6L31_RS03255
uniprot id: A0A8F8CQZ5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

465797:I6L31 RS06365
gene id: 465797:I6L31_RS06365
uniprot id: A0A8F8CS03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

465797:I6L31 RS15425
gene id: 465797:I6L31_RS15425
uniprot id: A0A8F8CPQ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS03145
gene id: 465797:I6L31_RS03145
uniprot id: A0A8F8GLX0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

465797:I6L31 RS09330
gene id: 465797:I6L31_RS09330
uniprot id: A0A8F8GK87
names: Similarity
messages: Belongs to the peptidase S8 family.

465797:I6L31 RS13205
gene id: 465797:I6L31_RS13205
uniprot id: A0A8F8CRJ9
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

465797:I6L31 RS07090
gene id: 465797:I6L31_RS07090
uniprot id: A0A8F8CV26
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

465797:I6L31 RS11370
gene id: 465797:I6L31_RS11370
uniprot id: A0A8F8CP07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

465797:I6L31 RS08655
gene id: 465797:I6L31_RS08655
uniprot id: A0A8F8GKD7
names: Similarity
messages: Belongs to the RelA/SpoT family.

465797:I6L31 RS08120
gene id: 465797:I6L31_RS08120
uniprot id: A0A8F8GN26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

465797:I6L31 RS13890
gene id: 465797:I6L31_RS13890
uniprot id: A0A8F8GK17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS07225
gene id: 465797:I6L31_RS07225
uniprot id: A0A8F8CSA5
names: Similarity
messages: Belongs to the peptidase S41A family.

465797:I6L31 RS09540
gene id: 465797:I6L31_RS09540
uniprot id: A0A8F8GKI9
names: Similarity
messages: Belongs to the GST superfamily.

465797:I6L31 RS01125
gene id: 465797:I6L31_RS01125
uniprot id: A0A8F8GLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465797:I6L31 RS04925
gene id: 465797:I6L31_RS04925
uniprot id: A0A8F8GMI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

465797:I6L31 RS01490
gene id: 465797:I6L31_RS01490
uniprot id: A0A8F8GMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS12405
gene id: 465797:I6L31_RS12405
uniprot id: A0A8F8GKQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

465797:I6L31 RS15215
gene id: 465797:I6L31_RS15215
uniprot id: A0A8F8GK98
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

465797:I6L31 RS01165
gene id: 465797:I6L31_RS01165
uniprot id: A0A8F8CT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

465797:I6L31 RS08555
gene id: 465797:I6L31_RS08555
uniprot id: A0A8F8CQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS14225
gene id: 465797:I6L31_RS14225
uniprot id: A0A8F8CU48
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

465797:I6L31 RS15325
gene id: 465797:I6L31_RS15325
uniprot id: A0A8F8CUJ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS17040
gene id: 465797:I6L31_RS17040
uniprot id: A0A8F8CTN2
names: Similarity
messages: Belongs to the GST superfamily.

465797:I6L31 RS00625
gene id: 465797:I6L31_RS00625
uniprot id: A0A8F8GLI1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

465797:I6L31 RS14720
gene id: 465797:I6L31_RS14720
uniprot id: A0A8F8GLE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

465797:I6L31 RS08830
gene id: 465797:I6L31_RS08830
uniprot id: A0A8F8GJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

465797:I6L31 RS15305
gene id: 465797:I6L31_RS15305
uniprot id: A0A8F8GLH5
names: Similarity
messages: Belongs to the UPF0145 family.

465797:I6L31 RS05545
gene id: 465797:I6L31_RS05545
uniprot id: A0A8F8GLG3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

465797:I6L31 RS04020
gene id: 465797:I6L31_RS04020
uniprot id: A0A8F8CW50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

465797:I6L31 RS07350
gene id: 465797:I6L31_RS07350
uniprot id: A0A8F8GMY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

465797:I6L31 RS13555
gene id: 465797:I6L31_RS13555
uniprot id: A0A8F8GJZ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS10570
gene id: 465797:I6L31_RS10570
uniprot id: A0A8F8GJI1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

465797:I6L31 RS01050
gene id: 465797:I6L31_RS01050
uniprot id: A0A8F8GLW7
names: Similarity
messages: Belongs to the asparaginase 1 family.

465797:I6L31 RS03100
gene id: 465797:I6L31_RS03100
uniprot id: A0A8F8CQX5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

465797:I6L31 RS15380
gene id: 465797:I6L31_RS15380
uniprot id: A0A8F8GL73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

465797:I6L31 RS17680
gene id: 465797:I6L31_RS17680
uniprot id: A0A8F8GM69
names: Similarity
messages: Belongs to the SBNO family.

465797:I6L31 RS14910
gene id: 465797:I6L31_RS14910
uniprot id: A0A8F8CS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

465797:I6L31 RS10530
gene id: 465797:I6L31_RS10530
uniprot id: A0A8F8CN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

465797:I6L31 RS01780
gene id: 465797:I6L31_RS01780
uniprot id: A0A8F8GJY8
names: Similarity
messages: Belongs to the peptidase M16 family.

465797:I6L31 RS03235
gene id: 465797:I6L31_RS03235
uniprot id: A0A8F8GM21
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS13815
gene id: 465797:I6L31_RS13815
uniprot id: A0A8F8GL22
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

465797:I6L31 RS10675
gene id: 465797:I6L31_RS10675
uniprot id: A0A8F8CN06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

465797:I6L31 RS10610
gene id: 465797:I6L31_RS10610
uniprot id: A0A8F8CN64
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS14120
gene id: 465797:I6L31_RS14120
uniprot id: A0A8F8GL00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

465797:I6L31 RS10075
gene id: 465797:I6L31_RS10075
uniprot id: A0A8F8CSF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

465797:I6L31 RS13230
gene id: 465797:I6L31_RS13230
uniprot id: A0A8F8GJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

465797:I6L31 RS14340
gene id: 465797:I6L31_RS14340
uniprot id: A0A8F8CVE0
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

465797:I6L31 RS04405
gene id: 465797:I6L31_RS04405
uniprot id: A0A8F8GMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS05045
gene id: 465797:I6L31_RS05045
uniprot id: A0A8F8CUE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS03615
gene id: 465797:I6L31_RS03615
uniprot id: A0A8F8CW47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

465797:I6L31 RS10020
gene id: 465797:I6L31_RS10020
uniprot id: A0A8F8GJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

465797:I6L31 RS03995
gene id: 465797:I6L31_RS03995
uniprot id: A0A8F8CR82
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

465797:I6L31 RS10495
gene id: 465797:I6L31_RS10495
uniprot id: A0A8F8GJH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

465797:I6L31 RS11260
gene id: 465797:I6L31_RS11260
uniprot id: A0A8F8CT02
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465797:I6L31 RS00930
gene id: 465797:I6L31_RS00930
uniprot id: A0A8F8CWI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

465797:I6L31 RS14370
gene id: 465797:I6L31_RS14370
uniprot id: A0A8F8GK48
names: Similarity
messages: Belongs to the citrate synthase family.

465797:I6L31 RS08910
gene id: 465797:I6L31_RS08910
uniprot id: A0A8F8GJ93
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

465797:I6L31 RS16120
gene id: 465797:I6L31_RS16120
uniprot id: A0A8F8GKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS13630
gene id: 465797:I6L31_RS13630
uniprot id: A0A8F8GKX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS05410
gene id: 465797:I6L31_RS05410
uniprot id: A0A8F8CRU0
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS06070
gene id: 465797:I6L31_RS06070
uniprot id: A0A8F8GMD2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465797:I6L31 RS01115
gene id: 465797:I6L31_RS01115
uniprot id: A0A8F8GLK7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

465797:I6L31 RS02805
gene id: 465797:I6L31_RS02805
uniprot id: A0A8F8CVN1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

465797:I6L31 RS12250
gene id: 465797:I6L31_RS12250
uniprot id: A0A8F8CP93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

465797:I6L31 RS10760
gene id: 465797:I6L31_RS10760
uniprot id: A0A8F8CN17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

465797:I6L31 RS17510
gene id: 465797:I6L31_RS17510
uniprot id: A0A8F8GMZ0
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

465797:I6L31 RS10755
gene id: 465797:I6L31_RS10755
uniprot id: A0A8F8CN16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

465797:I6L31 RS05015
gene id: 465797:I6L31_RS05015
uniprot id: A0A8F8GMD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

465797:I6L31 RS06580
gene id: 465797:I6L31_RS06580
uniprot id: A0A8F8CYA6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS12540
gene id: 465797:I6L31_RS12540
uniprot id: A0A8F8CNL2
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

465797:I6L31 RS07910
gene id: 465797:I6L31_RS07910
uniprot id: A0A8F8GKZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS08560
gene id: 465797:I6L31_RS08560
uniprot id: A0A8F8GID2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

465797:I6L31 RS11095
gene id: 465797:I6L31_RS11095
uniprot id: A0A8F8GKI0
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS09340
gene id: 465797:I6L31_RS09340
uniprot id: A0A8F8GKH8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

465797:I6L31 RS10880
gene id: 465797:I6L31_RS10880
uniprot id: A0A8F8CU85
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

465797:I6L31 RS11155
gene id: 465797:I6L31_RS11155
uniprot id: A0A8F8CUB4
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

465797:I6L31 RS13545
gene id: 465797:I6L31_RS13545
uniprot id: A0A8F8GJ54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

465797:I6L31 RS09370
gene id: 465797:I6L31_RS09370
uniprot id: A0A8F8CMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

465797:I6L31 RS05985
gene id: 465797:I6L31_RS05985
uniprot id: A0A8F8GMC8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

465797:I6L31 RS02105
gene id: 465797:I6L31_RS02105
uniprot id: A0A8F8CVF3
names: Similarity
messages: Belongs to the Gfa family.

465797:I6L31 RS04575
gene id: 465797:I6L31_RS04575
uniprot id: A0A8F8GMA3
names: Similarity
messages: Belongs to the IMPACT family.

465797:I6L31 RS15040
gene id: 465797:I6L31_RS15040
uniprot id: A0A8F8GL53
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

465797:I6L31 RS00425
gene id: 465797:I6L31_RS00425
uniprot id: A0A8F8CSV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS09675
gene id: 465797:I6L31_RS09675
uniprot id: A0A8F8CSC1
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS10560
gene id: 465797:I6L31_RS10560
uniprot id: A0A8F8GIN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

465797:I6L31 RS11555
gene id: 465797:I6L31_RS11555
uniprot id: A0A8F8CNG9
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08930
gene id: 465797:I6L31_RS08930
uniprot id: A0A8F8CSF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

465797:I6L31 RS15005
gene id: 465797:I6L31_RS15005
uniprot id: A0A8F8CS58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

465797:I6L31 RS12420
gene id: 465797:I6L31_RS12420
uniprot id: A0A8F8GJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

465797:I6L31 RS01840
gene id: 465797:I6L31_RS01840
uniprot id: A0A8F8CTC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

465797:I6L31 RS06250
gene id: 465797:I6L31_RS06250
uniprot id: A0A8F8GMR3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

465797:I6L31 RS04540
gene id: 465797:I6L31_RS04540
uniprot id: A0A8F8GL39
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

465797:I6L31 RS01450
gene id: 465797:I6L31_RS01450
uniprot id: A0A8F8CT68
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

465797:I6L31 RS15605
gene id: 465797:I6L31_RS15605
uniprot id: A0A8F8CUI9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

465797:I6L31 RS00940
gene id: 465797:I6L31_RS00940
uniprot id: A0A8F8CV72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

465797:I6L31 RS14075
gene id: 465797:I6L31_RS14075
uniprot id: A0A8F8CP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS05205
gene id: 465797:I6L31_RS05205
uniprot id: A0A8F8CRM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

465797:I6L31 RS11720
gene id: 465797:I6L31_RS11720
uniprot id: A0A8F8CNI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

465797:I6L31 RS04870
gene id: 465797:I6L31_RS04870
uniprot id: A0A8F8CRI4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

465797:I6L31 RS09315
gene id: 465797:I6L31_RS09315
uniprot id: A0A8F8CSE1
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS14685
gene id: 465797:I6L31_RS14685
uniprot id: A0A8F8CU24
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS10680
gene id: 465797:I6L31_RS10680
uniprot id: A0A8F8CN09
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

465797:I6L31 RS05565
gene id: 465797:I6L31_RS05565
uniprot id: A0A8F8CWV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

465797:I6L31 RS08660
gene id: 465797:I6L31_RS08660
uniprot id: A0A8F8GK89
names: Similarity
messages: Belongs to the RutC family.

465797:I6L31 RS06665
gene id: 465797:I6L31_RS06665
uniprot id: A0A8F8CX25
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS12820
gene id: 465797:I6L31_RS12820
uniprot id: A0A8F8CTI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS12245
gene id: 465797:I6L31_RS12245
uniprot id: A0A8F8GKT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS08755
gene id: 465797:I6L31_RS08755
uniprot id: A0A8F8CME8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

465797:I6L31 RS05935
gene id: 465797:I6L31_RS05935
uniprot id: A0A8F8CRV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465797:I6L31 RS02475
gene id: 465797:I6L31_RS02475
uniprot id: A0A8F8CQJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

465797:I6L31 RS01040
gene id: 465797:I6L31_RS01040
uniprot id: A0A8F8GLK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS06135
gene id: 465797:I6L31_RS06135
uniprot id: A0A8F8CUR7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465797:I6L31 RS03825
gene id: 465797:I6L31_RS03825
uniprot id: A0A8F8CRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

465797:I6L31 RS09365
gene id: 465797:I6L31_RS09365
uniprot id: A0A8F8CML3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

465797:I6L31 RS10300
gene id: 465797:I6L31_RS10300
uniprot id: A0A8F8CMW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

465797:I6L31 RS02895
gene id: 465797:I6L31_RS02895
uniprot id: A0A8F8CVU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS01185
gene id: 465797:I6L31_RS01185
uniprot id: A0A8F8CV50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

465797:I6L31 RS14290
gene id: 465797:I6L31_RS14290
uniprot id: A0A8F8GLB6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465797:I6L31 RS15105
gene id: 465797:I6L31_RS15105
uniprot id: A0A8F8CU76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

465797:I6L31 RS08170
gene id: 465797:I6L31_RS08170
uniprot id: A0A8F8CXK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

465797:I6L31 RS15175
gene id: 465797:I6L31_RS15175
uniprot id: A0A8F8CPN0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS07380
gene id: 465797:I6L31_RS07380
uniprot id: A0A8F8CSH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

465797:I6L31 RS07435
gene id: 465797:I6L31_RS07435
uniprot id: A0A8F8CST0
names: Similarity
messages: Belongs to the peptidase C56 family.

465797:I6L31 RS07905
gene id: 465797:I6L31_RS07905
uniprot id: A0A8F8CVC8
names: Similarity
messages: Belongs to the WrbA family.

465797:I6L31 RS12715
gene id: 465797:I6L31_RS12715
uniprot id: A0A8F8CNN0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

465797:I6L31 RS08055
gene id: 465797:I6L31_RS08055
uniprot id: A0A8F8CXQ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

465797:I6L31 RS14995
gene id: 465797:I6L31_RS14995
uniprot id: A0A8F8CPE1
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

465797:I6L31 RS07305
gene id: 465797:I6L31_RS07305
uniprot id: A0A8F8CSF7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS13945
gene id: 465797:I6L31_RS13945
uniprot id: A0A8F8CTS3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

465797:I6L31 RS10440
gene id: 465797:I6L31_RS10440
uniprot id: A0A8F8CSW6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

465797:I6L31 RS02580
gene id: 465797:I6L31_RS02580
uniprot id: A0A8F8GKZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

465797:I6L31 RS14740
gene id: 465797:I6L31_RS14740
uniprot id: A0A8F8CPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

465797:I6L31 RS04565
gene id: 465797:I6L31_RS04565
uniprot id: A0A8F8GLB0
names: Similarity
messages: Belongs to the universal stress protein A family.

465797:I6L31 RS14675
gene id: 465797:I6L31_RS14675
uniprot id: A0A8F8CS17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

465797:I6L31 RS11135
gene id: 465797:I6L31_RS11135
uniprot id: A0A8F8CN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

465797:I6L31 RS00840
gene id: 465797:I6L31_RS00840
uniprot id: A0A8F8CQD6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

465797:I6L31 RS01295
gene id: 465797:I6L31_RS01295
uniprot id: A0A8F8GJV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

465797:I6L31 RS13625
gene id: 465797:I6L31_RS13625
uniprot id: A0A8F8GJ59
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

465797:I6L31 RS00520
gene id: 465797:I6L31_RS00520
uniprot id: A0A8F8CUX7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

465797:I6L31 RS01785
gene id: 465797:I6L31_RS01785
uniprot id: A0A8F8GLP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

465797:I6L31 RS06840
gene id: 465797:I6L31_RS06840
uniprot id: A0A8F8GLN9
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS02745
gene id: 465797:I6L31_RS02745
uniprot id: A0A8F8GLZ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465797:I6L31 RS05880
gene id: 465797:I6L31_RS05880
uniprot id: A0A8F8CWX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

465797:I6L31 RS04035
gene id: 465797:I6L31_RS04035
uniprot id: A0A8F8GKB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

465797:I6L31 RS08585
gene id: 465797:I6L31_RS08585
uniprot id: A0A8F8CN84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

465797:I6L31 RS03080
gene id: 465797:I6L31_RS03080
uniprot id: A0A8F8GM80
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS09360
gene id: 465797:I6L31_RS09360
uniprot id: A0A8F8CML4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

465797:I6L31 RS16175
gene id: 465797:I6L31_RS16175
uniprot id: A0A8F8CUL5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

465797:I6L31 RS07410
gene id: 465797:I6L31_RS07410
uniprot id: A0A8F8GKW2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

465797:I6L31 RS17450
gene id: 465797:I6L31_RS17450
uniprot id: A0A8F8GN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS04290
gene id: 465797:I6L31_RS04290
uniprot id: A0A8F8GKD1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS07165
gene id: 465797:I6L31_RS07165
uniprot id: A0A8F8CXC4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

465797:I6L31 RS12340
gene id: 465797:I6L31_RS12340
uniprot id: A0A8F8CPA2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

465797:I6L31 RS01830
gene id: 465797:I6L31_RS01830
uniprot id: A0A8F8CQH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

465797:I6L31 RS10395
gene id: 465797:I6L31_RS10395
uniprot id: A0A8F8CSJ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS08505
gene id: 465797:I6L31_RS08505
uniprot id: A0A8F8GK78
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS06810
gene id: 465797:I6L31_RS06810
uniprot id: A0A8F8CYD8
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

465797:I6L31 RS01265
gene id: 465797:I6L31_RS01265
uniprot id: A0A8F8CQH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465797:I6L31 RS11085
gene id: 465797:I6L31_RS11085
uniprot id: A0A8F8CQW2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

465797:I6L31 RS01545
gene id: 465797:I6L31_RS01545
uniprot id: A0A8F8GLN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS13005
gene id: 465797:I6L31_RS13005
uniprot id: A0A8F8GL38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465797:I6L31 RS08100
gene id: 465797:I6L31_RS08100
uniprot id: A0A8F8CVE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

465797:I6L31 RS09755
gene id: 465797:I6L31_RS09755
uniprot id: A0A8F8CTW2
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

465797:I6L31 RS12745
gene id: 465797:I6L31_RS12745
uniprot id: A0A8F8CRG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

465797:I6L31 RS04865
gene id: 465797:I6L31_RS04865
uniprot id: A0A8F8GMZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465797:I6L31 RS11420
gene id: 465797:I6L31_RS11420
uniprot id: A0A8F8CT23
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

465797:I6L31 RS03475
gene id: 465797:I6L31_RS03475
uniprot id: A0A8F8GMA4
names: Similarity
messages: Belongs to the Skp family.

465797:I6L31 RS11200
gene id: 465797:I6L31_RS11200
uniprot id: A0A8F8GKT3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

465797:I6L31 RS14665
gene id: 465797:I6L31_RS14665
uniprot id: A0A8F8CPA3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

465797:I6L31 RS04495
gene id: 465797:I6L31_RS04495
uniprot id: A0A8F8CWG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

465797:I6L31 RS09045
gene id: 465797:I6L31_RS09045
uniprot id: A0A8F8CQ85
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

465797:I6L31 RS18080
gene id: 465797:I6L31_RS18080
uniprot id: A0A8F8CTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS13200
gene id: 465797:I6L31_RS13200
uniprot id: A0A8F8CP02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

465797:I6L31 RS16015
gene id: 465797:I6L31_RS16015
uniprot id: A0A8F8CQJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

465797:I6L31 RS05400
gene id: 465797:I6L31_RS05400
uniprot id: A0A8F8CRP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

465797:I6L31 RS10490
gene id: 465797:I6L31_RS10490
uniprot id: A0A8F8GKE8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

465797:I6L31 RS07355
gene id: 465797:I6L31_RS07355
uniprot id: A0A8F8GMR6
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

465797:I6L31 RS14345
gene id: 465797:I6L31_RS14345
uniprot id: A0A8F8CTY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS11115
gene id: 465797:I6L31_RS11115
uniprot id: A0A8F8GKS8
names: Function
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
messages: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.

465797:I6L31 RS07750
gene id: 465797:I6L31_RS07750
uniprot id: A0A8F8GN05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

465797:I6L31 RS05810
gene id: 465797:I6L31_RS05810
uniprot id: A0A8F8GLH8
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

465797:I6L31 RS02370
gene id: 465797:I6L31_RS02370
uniprot id: A0A8F8GKY0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

465797:I6L31 RS13760
gene id: 465797:I6L31_RS13760
uniprot id: A0A8F8CY40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS07570
gene id: 465797:I6L31_RS07570
uniprot id: A0A8F8CV88
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

465797:I6L31 RS11955
gene id: 465797:I6L31_RS11955
uniprot id: A0A8F8GN29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465797:I6L31 RS07535
gene id: 465797:I6L31_RS07535
uniprot id: A0A8F8CSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

465797:I6L31 RS04245
gene id: 465797:I6L31_RS04245
uniprot id: A0A8F8CWD8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

465797:I6L31 RS08430
gene id: 465797:I6L31_RS08430
uniprot id: A0A8F8CSX8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

465797:I6L31 RS05900
gene id: 465797:I6L31_RS05900
uniprot id: A0A8F8GMC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465797:I6L31 RS01575
gene id: 465797:I6L31_RS01575
uniprot id: A0A8F8GLS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

465797:I6L31 RS05865
gene id: 465797:I6L31_RS05865
uniprot id: A0A8F8CUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS10475
gene id: 465797:I6L31_RS10475
uniprot id: A0A8F8CSR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

465797:I6L31 RS07530
gene id: 465797:I6L31_RS07530
uniprot id: A0A8F8CSE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

465797:I6L31 RS04155
gene id: 465797:I6L31_RS04155
uniprot id: A0A8F8GM79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS13310
gene id: 465797:I6L31_RS13310
uniprot id: A0A8F8CTT5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

465797:I6L31 RS00640
gene id: 465797:I6L31_RS00640
uniprot id: A0A8F8GLU0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

465797:I6L31 RS05890
gene id: 465797:I6L31_RS05890
uniprot id: A0A8F8GKM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465797:I6L31 RS05635
gene id: 465797:I6L31_RS05635
uniprot id: A0A8F8GLG8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS09810
gene id: 465797:I6L31_RS09810
uniprot id: A0A8F8GKF0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

465797:I6L31 RS02265
gene id: 465797:I6L31_RS02265
uniprot id: A0A8F8CVM3
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS13520
gene id: 465797:I6L31_RS13520
uniprot id: A0A8F8CRM9
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

465797:I6L31 RS06520
gene id: 465797:I6L31_RS06520
uniprot id: A0A8F8GLL9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465797:I6L31 RS14175
gene id: 465797:I6L31_RS14175
uniprot id: A0A8F8CTV6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS12730
gene id: 465797:I6L31_RS12730
uniprot id: A0A8F8CUV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS10330
gene id: 465797:I6L31_RS10330
uniprot id: A0A8F8CQL6
names: Subunit
messages: Homodimer.

465797:I6L31 RS10715
gene id: 465797:I6L31_RS10715
uniprot id: A0A8F8GIP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS14160
gene id: 465797:I6L31_RS14160
uniprot id: A0A8F8CPB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

465797:I6L31 RS15655
gene id: 465797:I6L31_RS15655
uniprot id: A0A8F8CPL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

465797:I6L31 RS04585
gene id: 465797:I6L31_RS04585
uniprot id: A0A8F8CWH8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS04630
gene id: 465797:I6L31_RS04630
uniprot id: A0A8F8CUA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

465797:I6L31 RS10195
gene id: 465797:I6L31_RS10195
uniprot id: A0A8F8CNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

465797:I6L31 RS02195
gene id: 465797:I6L31_RS02195
uniprot id: A0A8F8GK10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS03460
gene id: 465797:I6L31_RS03460
uniprot id: A0A8F8GLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

465797:I6L31 RS03270
gene id: 465797:I6L31_RS03270
uniprot id: A0A8F8CX92
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS04780
gene id: 465797:I6L31_RS04780
uniprot id: A0A8F8CUB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

465797:I6L31 RS04885
gene id: 465797:I6L31_RS04885
uniprot id: A0A8F8CXR9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS06830
gene id: 465797:I6L31_RS06830
uniprot id: A0A8F8GKS7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS00960
gene id: 465797:I6L31_RS00960
uniprot id: A0A8F8GKP4
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

465797:I6L31 RS12260
gene id: 465797:I6L31_RS12260
uniprot id: A0A8F8CNI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465797:I6L31 RS02700
gene id: 465797:I6L31_RS02700
uniprot id: A0A8F8CX35
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS06640
gene id: 465797:I6L31_RS06640
uniprot id: A0A8F8CS35
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

465797:I6L31 RS10130
gene id: 465797:I6L31_RS10130
uniprot id: A0A8F8CMU2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS08090
gene id: 465797:I6L31_RS08090
uniprot id: A0A8F8CXJ7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

465797:I6L31 RS09120
gene id: 465797:I6L31_RS09120
uniprot id: A0A8F8CQ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

465797:I6L31 RS01315
gene id: 465797:I6L31_RS01315
uniprot id: A0A8F8GLR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

465797:I6L31 RS01625
gene id: 465797:I6L31_RS01625
uniprot id: A0A8F8CT89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

465797:I6L31 RS07365
gene id: 465797:I6L31_RS07365
uniprot id: A0A8F8CXG9
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

465797:I6L31 RS15150
gene id: 465797:I6L31_RS15150
uniprot id: A0A8F8GL87
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS12785
gene id: 465797:I6L31_RS12785
uniprot id: A0A8F8CTM4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS09150
gene id: 465797:I6L31_RS09150
uniprot id: A0A8F8CXX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

465797:I6L31 RS00935
gene id: 465797:I6L31_RS00935
uniprot id: A0A8F8CV21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS12155
gene id: 465797:I6L31_RS12155
uniprot id: A0A8F8GKY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

465797:I6L31 RS03370
gene id: 465797:I6L31_RS03370
uniprot id: A0A8F8GK76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

465797:I6L31 RS00465
gene id: 465797:I6L31_RS00465
uniprot id: A0A8F8GLT0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

465797:I6L31 RS01430
gene id: 465797:I6L31_RS01430
uniprot id: A0A8F8CT67
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

465797:I6L31 RS04625
gene id: 465797:I6L31_RS04625
uniprot id: A0A8F8CWH5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

465797:I6L31 RS16605
gene id: 465797:I6L31_RS16605
uniprot id: A0A8F8GMB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

465797:I6L31 RS02810
gene id: 465797:I6L31_RS02810
uniprot id: A0A8F8CVT3
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

465797:I6L31 RS00495
gene id: 465797:I6L31_RS00495
uniprot id: A0A8F8CQA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

465797:I6L31 RS12675
gene id: 465797:I6L31_RS12675
uniprot id: A0A8F8GKR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS14005
gene id: 465797:I6L31_RS14005
uniprot id: A0A8F8CP91
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

465797:I6L31 RS13100
gene id: 465797:I6L31_RS13100
uniprot id: A0A8F8CTR7
names: Similarity
messages: Belongs to the hyi family.

465797:I6L31 RS05190
gene id: 465797:I6L31_RS05190
uniprot id: A0A8F8CS37
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

465797:I6L31 RS09885
gene id: 465797:I6L31_RS09885
uniprot id: A0A8F8CSY6
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

465797:I6L31 RS01445
gene id: 465797:I6L31_RS01445
uniprot id: A0A8F8CVD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465797:I6L31 RS08960
gene id: 465797:I6L31_RS08960
uniprot id: A0A8F8CS41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

465797:I6L31 RS14750
gene id: 465797:I6L31_RS14750
uniprot id: A0A8F8CPI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

465797:I6L31 RS01725
gene id: 465797:I6L31_RS01725
uniprot id: A0A8F8GLT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

465797:I6L31 RS05535
gene id: 465797:I6L31_RS05535
uniprot id: A0A8F8GKK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS03845
gene id: 465797:I6L31_RS03845
uniprot id: A0A8F8CRB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

465797:I6L31 RS05305
gene id: 465797:I6L31_RS05305
uniprot id: A0A8F8CRN4
names: Similarity
messages: Belongs to the peptidase M24B family.

465797:I6L31 RS10950
gene id: 465797:I6L31_RS10950
uniprot id: A0A8F8CNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

465797:I6L31 RS15555
gene id: 465797:I6L31_RS15555
uniprot id: A0A8F8GLJ1
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS10220
gene id: 465797:I6L31_RS10220
uniprot id: A0A8F8CZ73
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

465797:I6L31 RS08230
gene id: 465797:I6L31_RS08230
uniprot id: A0A8F8CSS4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

465797:I6L31 RS03470
gene id: 465797:I6L31_RS03470
uniprot id: A0A8F8GL46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

465797:I6L31 RS11760
gene id: 465797:I6L31_RS11760
uniprot id: A0A8F8GKL5
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

465797:I6L31 RS13565
gene id: 465797:I6L31_RS13565
uniprot id: A0A8F8GL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS13535
gene id: 465797:I6L31_RS13535
uniprot id: A0A8F8CTS2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS04880
gene id: 465797:I6L31_RS04880
uniprot id: A0A8F8CUC1
names: Similarity
messages: Belongs to the peptidase C56 family.

465797:I6L31 RS01045
gene id: 465797:I6L31_RS01045
uniprot id: A0A8F8GKP9
names: Subcellular Location Annotation
messages: Cytoplasm

465797:I6L31 RS00585
gene id: 465797:I6L31_RS00585
uniprot id: A0A8F8CQ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS02845
gene id: 465797:I6L31_RS02845
uniprot id: A0A8F8GLZ7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

465797:I6L31 RS10550
gene id: 465797:I6L31_RS10550
uniprot id: A0A8F8CSS6
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07310
gene id: 465797:I6L31_RS07310
uniprot id: A0A8F8CV58
names: Similarity
messages: Belongs to the UPF0758 family.

465797:I6L31 RS08175
gene id: 465797:I6L31_RS08175
uniprot id: A0A8F8CXP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

465797:I6L31 RS17900
gene id: 465797:I6L31_RS17900
uniprot id: A0A8F8CW32
names: Similarity
messages: Belongs to the FrmR/RcnR family.

465797:I6L31 RS08865
gene id: 465797:I6L31_RS08865
uniprot id: A0A8F8CMG0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

465797:I6L31 RS03780
gene id: 465797:I6L31_RS03780
uniprot id: A0A8F8CW11
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

465797:I6L31 RS15740
gene id: 465797:I6L31_RS15740
uniprot id: A0A8F8CUP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

465797:I6L31 RS11165
gene id: 465797:I6L31_RS11165
uniprot id: A0A8F8CSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

465797:I6L31 RS04410
gene id: 465797:I6L31_RS04410
uniprot id: A0A8F8GM93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS09140
gene id: 465797:I6L31_RS09140
uniprot id: A0A8F8GKG6
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11980
gene id: 465797:I6L31_RS11980
uniprot id: A0A8F8GKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

465797:I6L31 RS13510
gene id: 465797:I6L31_RS13510
uniprot id: A0A8F8CNW6
names: Similarity
messages: Belongs to the YjdM family.

465797:I6L31 RS14615
gene id: 465797:I6L31_RS14615
uniprot id: A0A8F8GJC1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

465797:I6L31 RS12635
gene id: 465797:I6L31_RS12635
uniprot id: A0A8F8CRC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

465797:I6L31 RS12040
gene id: 465797:I6L31_RS12040
uniprot id: A0A8F8CR76
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS01805
gene id: 465797:I6L31_RS01805
uniprot id: A0A8F8GLU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

465797:I6L31 RS05430
gene id: 465797:I6L31_RS05430
uniprot id: A0A8F8CWS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS08155
gene id: 465797:I6L31_RS08155
uniprot id: A0A8F8GN16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

465797:I6L31 RS04230
gene id: 465797:I6L31_RS04230
uniprot id: A0A8F8GME8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

465797:I6L31 RS09130
gene id: 465797:I6L31_RS09130
uniprot id: A0A8F8GK77
names: Similarity
messages: Belongs to the UPF0053 family.

465797:I6L31 RS03245
gene id: 465797:I6L31_RS03245
uniprot id: A0A8F8CW17
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

465797:I6L31 RS10115
gene id: 465797:I6L31_RS10115
uniprot id: A0A8F8CNM8
names: Similarity
messages: Belongs to the RecJ family.

465797:I6L31 RS15340
gene id: 465797:I6L31_RS15340
uniprot id: A0A8F8CPI0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

465797:I6L31 RS15455
gene id: 465797:I6L31_RS15455
uniprot id: A0A8F8GJH0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS07480
gene id: 465797:I6L31_RS07480
uniprot id: A0A8F8CXG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

465797:I6L31 RS15765
gene id: 465797:I6L31_RS15765
uniprot id: A0A8F8CVW9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS13155
gene id: 465797:I6L31_RS13155
uniprot id: A0A8F8GJX6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

465797:I6L31 RS00395
gene id: 465797:I6L31_RS00395
uniprot id: A0A8F8GLK8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

465797:I6L31 RS04045
gene id: 465797:I6L31_RS04045
uniprot id: A0A8F8GL80
names: Similarity
messages: Belongs to the GST superfamily.

465797:I6L31 RS15275
gene id: 465797:I6L31_RS15275
uniprot id: A0A8F8CU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

465797:I6L31 RS11985
gene id: 465797:I6L31_RS11985
uniprot id: A0A8F8GKS0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS15820
gene id: 465797:I6L31_RS15820
uniprot id: A0A8F8CQB5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

465797:I6L31 RS15290
gene id: 465797:I6L31_RS15290
uniprot id: A0A8F8GJG0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

465797:I6L31 RS15025
gene id: 465797:I6L31_RS15025
uniprot id: A0A8F8CUB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

465797:I6L31 RS03220
gene id: 465797:I6L31_RS03220
uniprot id: A0A8F8GLX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

465797:I6L31 RS06705
gene id: 465797:I6L31_RS06705
uniprot id: A0A8F8CSJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS08105
gene id: 465797:I6L31_RS08105
uniprot id: A0A8F8GL03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

465797:I6L31 RS01120
gene id: 465797:I6L31_RS01120
uniprot id: A0A8F8GKQ4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

465797:I6L31 RS03410
gene id: 465797:I6L31_RS03410
uniprot id: A0A8F8CR15
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

465797:I6L31 RS03880
gene id: 465797:I6L31_RS03880
uniprot id: A0A8F8GM15
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

465797:I6L31 RS06310
gene id: 465797:I6L31_RS06310
uniprot id: A0A8F8CUT9
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

465797:I6L31 RS13055
gene id: 465797:I6L31_RS13055
uniprot id: A0A8F8CT18
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

465797:I6L31 RS08015
gene id: 465797:I6L31_RS08015
uniprot id: A0A8F8GMV4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

465797:I6L31 RS00885
gene id: 465797:I6L31_RS00885
uniprot id: A0A8F8GKN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

465797:I6L31 RS03760
gene id: 465797:I6L31_RS03760
uniprot id: A0A8F8CR54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS13725
gene id: 465797:I6L31_RS13725
uniprot id: A0A8F8GL17
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

465797:I6L31 RS09375
gene id: 465797:I6L31_RS09375
uniprot id: A0A8F8CQ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

465797:I6L31 RS15320
gene id: 465797:I6L31_RS15320
uniprot id: A0A8F8CQ62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

465797:I6L31 RS14955
gene id: 465797:I6L31_RS14955
uniprot id: A0A8F8GK84
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

465797:I6L31 RS04010
gene id: 465797:I6L31_RS04010
uniprot id: A0A8F8CU26
names: Subcellular Location Annotation
messages: Cytoplasm

465797:I6L31 RS12135
gene id: 465797:I6L31_RS12135
uniprot id: A0A8F8CR90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

465797:I6L31 RS10775
gene id: 465797:I6L31_RS10775
uniprot id: A0A8F8CU75
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

465797:I6L31 RS03580
gene id: 465797:I6L31_RS03580
uniprot id: A0A8F8CW58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

465797:I6L31 RS09040
gene id: 465797:I6L31_RS09040
uniprot id: A0A8F8CSB2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465797:I6L31 RS18005
gene id: 465797:I6L31_RS18005
uniprot id: A0A8F8CZL6
names: Function
messages: Involved in the transposition of the insertion sequence.

465797:I6L31 RS05025
gene id: 465797:I6L31_RS05025
uniprot id: A0A8F8CWN3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465797:I6L31 RS08345
gene id: 465797:I6L31_RS08345
uniprot id: A0A8F8GL19
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS00795
gene id: 465797:I6L31_RS00795
uniprot id: A0A8F8GLJ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

465797:I6L31 RS09805
gene id: 465797:I6L31_RS09805
uniprot id: A0A8F8GKK3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS16050
gene id: 465797:I6L31_RS16050
uniprot id: A0A8F8GLM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS08900
gene id: 465797:I6L31_RS08900
uniprot id: A0A8F8GIF0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465797:I6L31 RS11310
gene id: 465797:I6L31_RS11310
uniprot id: A0A8F8CN74
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS12920
gene id: 465797:I6L31_RS12920
uniprot id: A0A8F8GL33
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

465797:I6L31 RS07850
gene id: 465797:I6L31_RS07850
uniprot id: A0A8F8GN10
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

465797:I6L31 RS00645
gene id: 465797:I6L31_RS00645
uniprot id: A0A8F8GN46
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

465797:I6L31 RS14185
gene id: 465797:I6L31_RS14185
uniprot id: A0A8F8CU09
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

465797:I6L31 RS08640
gene id: 465797:I6L31_RS08640
uniprot id: A0A8F8GID7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

465797:I6L31 RS02860
gene id: 465797:I6L31_RS02860
uniprot id: A0A8F8CQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

465797:I6L31 RS08935
gene id: 465797:I6L31_RS08935
uniprot id: A0A8F8CMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

465797:I6L31 RS05435
gene id: 465797:I6L31_RS05435
uniprot id: A0A8F8CUI7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

465797:I6L31 RS12680
gene id: 465797:I6L31_RS12680
uniprot id: A0A8F8GJU8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08085
gene id: 465797:I6L31_RS08085
uniprot id: A0A8F8CYT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

465797:I6L31 RS01800
gene id: 465797:I6L31_RS01800
uniprot id: A0A8F8GM08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

465797:I6L31 RS06380
gene id: 465797:I6L31_RS06380
uniprot id: A0A8F8CUU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS12140
gene id: 465797:I6L31_RS12140
uniprot id: A0A8F8GIX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS00610
gene id: 465797:I6L31_RS00610
uniprot id: A0A8F8CV31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

465797:I6L31 RS05955
gene id: 465797:I6L31_RS05955
uniprot id: A0A8F8CWT8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

465797:I6L31 RS03915
gene id: 465797:I6L31_RS03915
uniprot id: A0A8F8CR73
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

465797:I6L31 RS02330
gene id: 465797:I6L31_RS02330
uniprot id: A0A8F8CQV0
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

465797:I6L31 RS13385
gene id: 465797:I6L31_RS13385
uniprot id: A0A8F8CTU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

465797:I6L31 RS14690
gene id: 465797:I6L31_RS14690
uniprot id: A0A8F8CU74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS17085
gene id: 465797:I6L31_RS17085
uniprot id: A0A8F8GNJ8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

465797:I6L31 RS09170
gene id: 465797:I6L31_RS09170
uniprot id: A0A8F8CMJ5
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

465797:I6L31 RS01405
gene id: 465797:I6L31_RS01405
uniprot id: A0A8F8CQZ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

465797:I6L31 RS15905
gene id: 465797:I6L31_RS15905
uniprot id: A0A8F8CQC5
names: Similarity
messages: Belongs to the MobA/MobL family.

465797:I6L31 RS12710
gene id: 465797:I6L31_RS12710
uniprot id: A0A8F8CNN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

465797:I6L31 RS12425
gene id: 465797:I6L31_RS12425
uniprot id: A0A8F8GL04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

465797:I6L31 RS03670
gene id: 465797:I6L31_RS03670
uniprot id: A0A8F8CR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS10970
gene id: 465797:I6L31_RS10970
uniprot id: A0A8F8CSX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

465797:I6L31 RS02730
gene id: 465797:I6L31_RS02730
uniprot id: A0A8F8GLU7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08565
gene id: 465797:I6L31_RS08565
uniprot id: A0A8F8GK46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

465797:I6L31 RS11905
gene id: 465797:I6L31_RS11905
uniprot id: A0A8F8CNE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

465797:I6L31 RS13785
gene id: 465797:I6L31_RS13785
uniprot id: A0A8F8CRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

465797:I6L31 RS10405
gene id: 465797:I6L31_RS10405
uniprot id: A0A8F8CQM5
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

465797:I6L31 RS10045
gene id: 465797:I6L31_RS10045
uniprot id: A0A8F8CSS0
names: Similarity
messages: Belongs to the SsuE family.

465797:I6L31 RS03325
gene id: 465797:I6L31_RS03325
uniprot id: A0A8F8CR01
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465797:I6L31 RS06600
gene id: 465797:I6L31_RS06600
uniprot id: A0A8F8GKR1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

465797:I6L31 RS14830
gene id: 465797:I6L31_RS14830
uniprot id: A0A8F8CPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

465797:I6L31 RS04165
gene id: 465797:I6L31_RS04165
uniprot id: A0A8F8CWC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

465797:I6L31 RS10975
gene id: 465797:I6L31_RS10975
uniprot id: A0A8F8CQU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

465797:I6L31 RS08390
gene id: 465797:I6L31_RS08390
uniprot id: A0A8F8CSQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465797:I6L31 RS02080
gene id: 465797:I6L31_RS02080
uniprot id: A0A8F8CQL2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS10485
gene id: 465797:I6L31_RS10485
uniprot id: A0A8F8GIN1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

465797:I6L31 RS13400
gene id: 465797:I6L31_RS13400
uniprot id: A0A8F8CP21
names: Subcellular Location Annotation
messages: Cell inner membrane

465797:I6L31 RS09250
gene id: 465797:I6L31_RS09250
uniprot id: A0A8F8GK82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

465797:I6L31 RS11290
gene id: 465797:I6L31_RS11290
uniprot id: A0A8F8GKN0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

465797:I6L31 RS10940
gene id: 465797:I6L31_RS10940
uniprot id: A0A8F8CN36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

465797:I6L31 RS12550
gene id: 465797:I6L31_RS12550
uniprot id: A0A8F8CNS4
names: Similarity
messages: Belongs to the Gfa family.

465797:I6L31 RS04695
gene id: 465797:I6L31_RS04695
uniprot id: A0A8F8CXQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465797:I6L31 RS13330
gene id: 465797:I6L31_RS13330
uniprot id: A0A8F8CRK9
names: Similarity
messages: Belongs to the thioredoxin family.

465797:I6L31 RS12940
gene id: 465797:I6L31_RS12940
uniprot id: A0A8F8CNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

465797:I6L31 RS09085
gene id: 465797:I6L31_RS09085
uniprot id: A0A8F8CMI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

465797:I6L31 RS07605
gene id: 465797:I6L31_RS07605
uniprot id: A0A8F8CXK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS13485
gene id: 465797:I6L31_RS13485
uniprot id: A0A8F8GL01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

465797:I6L31 RS14980
gene id: 465797:I6L31_RS14980
uniprot id: A0A8F8CPE2
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS05245
gene id: 465797:I6L31_RS05245
uniprot id: A0A8F8CWK4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

465797:I6L31 RS09055
gene id: 465797:I6L31_RS09055
uniprot id: A0A8F8GK74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS04295
gene id: 465797:I6L31_RS04295
uniprot id: A0A8F8GM39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

465797:I6L31 RS11300
gene id: 465797:I6L31_RS11300
uniprot id: A0A8F8CT64
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

465797:I6L31 RS10575
gene id: 465797:I6L31_RS10575
uniprot id: A0A8F8GKP8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08065
gene id: 465797:I6L31_RS08065
uniprot id: A0A8F8CSL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

465797:I6L31 RS12255
gene id: 465797:I6L31_RS12255
uniprot id: A0A8F8CTG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

465797:I6L31 RS04095
gene id: 465797:I6L31_RS04095
uniprot id: A0A8F8CR99
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS18180
gene id: 465797:I6L31_RS18180
uniprot id: A0A8F8CTF2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

465797:I6L31 RS03425
gene id: 465797:I6L31_RS03425
uniprot id: A0A8F8CXB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

465797:I6L31 RS03330
gene id: 465797:I6L31_RS03330
uniprot id: A0A8F8CR02
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

465797:I6L31 RS04205
gene id: 465797:I6L31_RS04205
uniprot id: A0A8F8CU49
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

465797:I6L31 RS05915
gene id: 465797:I6L31_RS05915
uniprot id: A0A8F8GMI1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

465797:I6L31 RS02290
gene id: 465797:I6L31_RS02290
uniprot id: A0A8F8CXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

465797:I6L31 RS07895
gene id: 465797:I6L31_RS07895
uniprot id: A0A8F8CXH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS15345
gene id: 465797:I6L31_RS15345
uniprot id: A0A8F8CPP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

465797:I6L31 RS15855
gene id: 465797:I6L31_RS15855
uniprot id: A0A8F8CSG1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

465797:I6L31 RS03990
gene id: 465797:I6L31_RS03990
uniprot id: A0A8F8CWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

465797:I6L31 RS04670
gene id: 465797:I6L31_RS04670
uniprot id: A0A8F8CWI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

465797:I6L31 RS01715
gene id: 465797:I6L31_RS01715
uniprot id: A0A8F8GKU0
names: Similarity
messages: Belongs to the peptidase M16 family.

465797:I6L31 RS12535
gene id: 465797:I6L31_RS12535
uniprot id: A0A8F8CTJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

465797:I6L31 RS11995
gene id: 465797:I6L31_RS11995
uniprot id: A0A8F8CTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS03585
gene id: 465797:I6L31_RS03585
uniprot id: A0A8F8CR34
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08815
gene id: 465797:I6L31_RS08815
uniprot id: A0A8F8CQ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

465797:I6L31 RS02590
gene id: 465797:I6L31_RS02590
uniprot id: A0A8F8GLY3
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS02150
gene id: 465797:I6L31_RS02150
uniprot id: A0A8F8CVN8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

465797:I6L31 RS08110
gene id: 465797:I6L31_RS08110
uniprot id: A0A8F8GMQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

465797:I6L31 RS03335
gene id: 465797:I6L31_RS03335
uniprot id: A0A8F8CR55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

465797:I6L31 RS11120
gene id: 465797:I6L31_RS11120
uniprot id: A0A8F8GKL9
names: Function
names: Similarity
messages: Belongs to the isochorismatase family. RutB subfamily.
messages: Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.

465797:I6L31 RS08075
gene id: 465797:I6L31_RS08075
uniprot id: A0A8F8CVE5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

465797:I6L31 RS14200
gene id: 465797:I6L31_RS14200
uniprot id: A0A8F8GL05
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

465797:I6L31 RS03350
gene id: 465797:I6L31_RS03350
uniprot id: A0A8F8CVV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

465797:I6L31 RS10270
gene id: 465797:I6L31_RS10270
uniprot id: A0A8F8GJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS05910
gene id: 465797:I6L31_RS05910
uniprot id: A0A8F8GMP3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465797:I6L31 RS12860
gene id: 465797:I6L31_RS12860
uniprot id: A0A8F8CTN5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

465797:I6L31 RS15310
gene id: 465797:I6L31_RS15310
uniprot id: A0A8F8GLA9
names: Similarity
messages: Belongs to the UPF0145 family.

465797:I6L31 RS10820
gene id: 465797:I6L31_RS10820
uniprot id: A0A8F8GIQ2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

465797:I6L31 RS04930
gene id: 465797:I6L31_RS04930
uniprot id: A0A8F8GMC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

465797:I6L31 RS13130
gene id: 465797:I6L31_RS13130
uniprot id: A0A8F8CTH7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

465797:I6L31 RS16705
gene id: 465797:I6L31_RS16705
uniprot id: A0A8F8CYJ8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

465797:I6L31 RS14105
gene id: 465797:I6L31_RS14105
uniprot id: A0A8F8CTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

465797:I6L31 RS07670
gene id: 465797:I6L31_RS07670
uniprot id: A0A8F8GN01
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

465797:I6L31 RS11265
gene id: 465797:I6L31_RS11265
uniprot id: A0A8F8CQY3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465797:I6L31 RS05490
gene id: 465797:I6L31_RS05490
uniprot id: A0A8F8CRQ5
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

465797:I6L31 RS04005
gene id: 465797:I6L31_RS04005
uniprot id: A0A8F8CRD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

465797:I6L31 RS14365
gene id: 465797:I6L31_RS14365
uniprot id: A0A8F8GL15
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

465797:I6L31 RS14735
gene id: 465797:I6L31_RS14735
uniprot id: A0A8F8CUB5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

465797:I6L31 RS15500
gene id: 465797:I6L31_RS15500
uniprot id: A0A8F8CPJ8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11160
gene id: 465797:I6L31_RS11160
uniprot id: A0A8F8CST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

465797:I6L31 RS12770
gene id: 465797:I6L31_RS12770
uniprot id: A0A8F8GKW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

465797:I6L31 RS03300
gene id: 465797:I6L31_RS03300
uniprot id: A0A8F8GL36
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

465797:I6L31 RS17010
gene id: 465797:I6L31_RS17010
uniprot id: A0A8F8GNC7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

465797:I6L31 RS07865
gene id: 465797:I6L31_RS07865
uniprot id: A0A8F8CXN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

465797:I6L31 RS17055
gene id: 465797:I6L31_RS17055
uniprot id: A0A8F8CYJ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

465797:I6L31 RS13840
gene id: 465797:I6L31_RS13840
uniprot id: A0A8F8CP72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

465797:I6L31 RS09780
gene id: 465797:I6L31_RS09780
uniprot id: A0A8F8GKA9
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

465797:I6L31 RS16710
gene id: 465797:I6L31_RS16710
uniprot id: A0A8F8CTG8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

465797:I6L31 RS08095
gene id: 465797:I6L31_RS08095
uniprot id: A0A8F8CXN1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

465797:I6L31 RS14465
gene id: 465797:I6L31_RS14465
uniprot id: A0A8F8CU82
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11270
gene id: 465797:I6L31_RS11270
uniprot id: A0A8F8GIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS09070
gene id: 465797:I6L31_RS09070
uniprot id: A0A8F8GKB0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

465797:I6L31 RS06875
gene id: 465797:I6L31_RS06875
uniprot id: A0A8F8CSA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS05845
gene id: 465797:I6L31_RS05845
uniprot id: A0A8F8CRY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS10460
gene id: 465797:I6L31_RS10460
uniprot id: A0A8F8CQM0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

465797:I6L31 RS16270
gene id: 465797:I6L31_RS16270
uniprot id: A0A8F8CUS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS16720
gene id: 465797:I6L31_RS16720
uniprot id: A0A8F8CTJ2
names: Similarity
messages: Belongs to the HsdR family.

465797:I6L31 RS15030
gene id: 465797:I6L31_RS15030
uniprot id: A0A8F8CS70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS12690
gene id: 465797:I6L31_RS12690
uniprot id: A0A8F8GKV8
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

465797:I6L31 RS04755
gene id: 465797:I6L31_RS04755
uniprot id: A0A8F8CRH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

465797:I6L31 RS01270
gene id: 465797:I6L31_RS01270
uniprot id: A0A8F8CT48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

465797:I6L31 RS16215
gene id: 465797:I6L31_RS16215
uniprot id: A0A8F8CQG2
names: Similarity
messages: Belongs to the YkuD family.

465797:I6L31 RS08840
gene id: 465797:I6L31_RS08840
uniprot id: A0A8F8GK99
names: Similarity
messages: Belongs to the GSP N family.

465797:I6L31 RS13195
gene id: 465797:I6L31_RS13195
uniprot id: A0A8F8CNT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

465797:I6L31 RS09585
gene id: 465797:I6L31_RS09585
uniprot id: A0A8F8CTU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

465797:I6L31 RS14635
gene id: 465797:I6L31_RS14635
uniprot id: A0A8F8GL69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

465797:I6L31 RS09380
gene id: 465797:I6L31_RS09380
uniprot id: A0A8F8CTS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

465797:I6L31 RS09515
gene id: 465797:I6L31_RS09515
uniprot id: A0A8F8CQD1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

465797:I6L31 RS12220
gene id: 465797:I6L31_RS12220
uniprot id: A0A8F8GIY0
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

465797:I6L31 RS17100
gene id: 465797:I6L31_RS17100
uniprot id: A0A8F8CYP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

465797:I6L31 RS14400
gene id: 465797:I6L31_RS14400
uniprot id: A0A8F8CP71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

465797:I6L31 RS00970
gene id: 465797:I6L31_RS00970
uniprot id: A0A8F8GLP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

465797:I6L31 RS00550
gene id: 465797:I6L31_RS00550
uniprot id: A0A8F8GLT5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

465797:I6L31 RS14410
gene id: 465797:I6L31_RS14410
uniprot id: A0A8F8CRY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

465797:I6L31 RS06620
gene id: 465797:I6L31_RS06620
uniprot id: A0A8F8GMT5
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

465797:I6L31 RS10365
gene id: 465797:I6L31_RS10365
uniprot id: A0A8F8CSV7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

465797:I6L31 RS17525
gene id: 465797:I6L31_RS17525
uniprot id: A0A8F8GNC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

465797:I6L31 RS05905
gene id: 465797:I6L31_RS05905
uniprot id: A0A8F8GLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

465797:I6L31 RS00730
gene id: 465797:I6L31_RS00730
uniprot id: A0A8F8GLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS11520
gene id: 465797:I6L31_RS11520
uniprot id: A0A8F8GJN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

465797:I6L31 RS10965
gene id: 465797:I6L31_RS10965
uniprot id: A0A8F8CSR6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

465797:I6L31 RS12385
gene id: 465797:I6L31_RS12385
uniprot id: A0A8F8CTD4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

465797:I6L31 RS11305
gene id: 465797:I6L31_RS11305
uniprot id: A0A8F8CN78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

465797:I6L31 RS14355
gene id: 465797:I6L31_RS14355
uniprot id: A0A8F8CRZ6
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS13670
gene id: 465797:I6L31_RS13670
uniprot id: A0A8F8CNY6
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

465797:I6L31 RS00490
gene id: 465797:I6L31_RS00490
uniprot id: A0A8F8CQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

465797:I6L31 RS11285
gene id: 465797:I6L31_RS11285
uniprot id: A0A8F8GKT9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

465797:I6L31 RS10660
gene id: 465797:I6L31_RS10660
uniprot id: A0A8F8GKJ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS06805
gene id: 465797:I6L31_RS06805
uniprot id: A0A8F8CUZ3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

465797:I6L31 RS05760
gene id: 465797:I6L31_RS05760
uniprot id: A0A8F8CRT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

465797:I6L31 RS15370
gene id: 465797:I6L31_RS15370
uniprot id: A0A8F8CSA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS10925
gene id: 465797:I6L31_RS10925
uniprot id: A0A8F8GKK9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

465797:I6L31 RS02940
gene id: 465797:I6L31_RS02940
uniprot id: A0A8F8CQV4
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS02405
gene id: 465797:I6L31_RS02405
uniprot id: A0A8F8CQV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

465797:I6L31 RS05595
gene id: 465797:I6L31_RS05595
uniprot id: A0A8F8CUK1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS02760
gene id: 465797:I6L31_RS02760
uniprot id: A0A8F8CQT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS02070
gene id: 465797:I6L31_RS02070
uniprot id: A0A8F8CR62
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

465797:I6L31 RS05870
gene id: 465797:I6L31_RS05870
uniprot id: A0A8F8CY20
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

465797:I6L31 RS08130
gene id: 465797:I6L31_RS08130
uniprot id: A0A8F8CSZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

465797:I6L31 RS07445
gene id: 465797:I6L31_RS07445
uniprot id: A0A8F8CSD4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS16065
gene id: 465797:I6L31_RS16065
uniprot id: A0A8F8CUT4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS12070
gene id: 465797:I6L31_RS12070
uniprot id: A0A8F8CP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

465797:I6L31 RS07325
gene id: 465797:I6L31_RS07325
uniprot id: A0A8F8CXE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS11935
gene id: 465797:I6L31_RS11935
uniprot id: A0A8F8CT28
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS12210
gene id: 465797:I6L31_RS12210
uniprot id: A0A8F8CTB6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

465797:I6L31 RS11385
gene id: 465797:I6L31_RS11385
uniprot id: A0A8F8CN85
names: Similarity
messages: Belongs to the phosphohexose mutase family.

465797:I6L31 RS12955
gene id: 465797:I6L31_RS12955
uniprot id: A0A8F8CRG5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

465797:I6L31 RS11900
gene id: 465797:I6L31_RS11900
uniprot id: A0A8F8CTC8
names: Similarity
messages: Belongs to the TPP enzyme family.

465797:I6L31 RS13885
gene id: 465797:I6L31_RS13885
uniprot id: A0A8F8GKY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

465797:I6L31 RS00405
gene id: 465797:I6L31_RS00405
uniprot id: A0A8F8CV46
names: Similarity
messages: Belongs to the peptidase S16 family.

465797:I6L31 RS13895
gene id: 465797:I6L31_RS13895
uniprot id: A0A8F8GL91
names: Similarity
messages: Belongs to the GSP E family.

465797:I6L31 RS02935
gene id: 465797:I6L31_RS02935
uniprot id: A0A8F8CVX4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

465797:I6L31 RS00435
gene id: 465797:I6L31_RS00435
uniprot id: A0A8F8CUW7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

465797:I6L31 RS14825
gene id: 465797:I6L31_RS14825
uniprot id: A0A8F8CPC1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

465797:I6L31 RS10170
gene id: 465797:I6L31_RS10170
uniprot id: A0A8F8GKC8
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

465797:I6L31 RS11075
gene id: 465797:I6L31_RS11075
uniprot id: A0A8F8CSS5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

465797:I6L31 RS02830
gene id: 465797:I6L31_RS02830
uniprot id: A0A8F8GL07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Aromatic acid:H(+) symporter (AAHS) (TC 2.A.1.15) family.
messages: Membrane

465797:I6L31 RS03535
gene id: 465797:I6L31_RS03535
uniprot id: A0A8F8GK86
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

465797:I6L31 RS08895
gene id: 465797:I6L31_RS08895
uniprot id: A0A8F8CQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

465797:I6L31 RS07385
gene id: 465797:I6L31_RS07385
uniprot id: A0A8F8CV67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

465797:I6L31 RS09815
gene id: 465797:I6L31_RS09815
uniprot id: A0A8F8CY29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

465797:I6L31 RS10070
gene id: 465797:I6L31_RS10070
uniprot id: A0A8F8CTY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

465797:I6L31 RS05725
gene id: 465797:I6L31_RS05725
uniprot id: A0A8F8GMB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

465797:I6L31 RS05875
gene id: 465797:I6L31_RS05875
uniprot id: A0A8F8CWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

465797:I6L31 RS17385
gene id: 465797:I6L31_RS17385
uniprot id: A0A8F8GLJ7
names: Similarity
messages: Belongs to the ParB family.

465797:I6L31 RS00965
gene id: 465797:I6L31_RS00965
uniprot id: A0A8F8GLW0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

465797:I6L31 RS08045
gene id: 465797:I6L31_RS08045
uniprot id: A0A8F8GMV6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

465797:I6L31 RS15585
gene id: 465797:I6L31_RS15585
uniprot id: A0A8F8CPS7
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS02050
gene id: 465797:I6L31_RS02050
uniprot id: A0A8F8GMY7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

465797:I6L31 RS09255
gene id: 465797:I6L31_RS09255
uniprot id: A0A8F8GJB1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS04650
gene id: 465797:I6L31_RS04650
uniprot id: A0A8F8GLB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465797:I6L31 RS05090
gene id: 465797:I6L31_RS05090
uniprot id: A0A8F8GMJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

465797:I6L31 RS06360
gene id: 465797:I6L31_RS06360
uniprot id: A0A8F8CX40
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

465797:I6L31 RS10745
gene id: 465797:I6L31_RS10745
uniprot id: A0A8F8CNU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS16995
gene id: 465797:I6L31_RS16995
uniprot id: A0A8F8GN61
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

465797:I6L31 RS11330
gene id: 465797:I6L31_RS11330
uniprot id: A0A8F8CSV2
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS03795
gene id: 465797:I6L31_RS03795
uniprot id: A0A8F8CTZ8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

465797:I6L31 RS02190
gene id: 465797:I6L31_RS02190
uniprot id: A0A8F8CTF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

465797:I6L31 RS00505
gene id: 465797:I6L31_RS00505
uniprot id: A0A8F8CWD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

465797:I6L31 RS14080
gene id: 465797:I6L31_RS14080
uniprot id: A0A8F8CP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

465797:I6L31 RS08745
gene id: 465797:I6L31_RS08745
uniprot id: A0A8F8CNA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

465797:I6L31 RS11480
gene id: 465797:I6L31_RS11480
uniprot id: A0A8F8CQZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS10165
gene id: 465797:I6L31_RS10165
uniprot id: A0A8F8GIL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

465797:I6L31 RS08765
gene id: 465797:I6L31_RS08765
uniprot id: A0A8F8CMM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

465797:I6L31 RS18105
gene id: 465797:I6L31_RS18105
uniprot id: A0A8F8CYE5
names: Similarity
messages: Belongs to the glutamate synthase family.

465797:I6L31 RS10605
gene id: 465797:I6L31_RS10605
uniprot id: A0A8F8CMZ9
names: Similarity
messages: Belongs to the UPF0260 family.

465797:I6L31 RS13120
gene id: 465797:I6L31_RS13120
uniprot id: A0A8F8CRI9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

465797:I6L31 RS01865
gene id: 465797:I6L31_RS01865
uniprot id: A0A8F8GJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS12605
gene id: 465797:I6L31_RS12605
uniprot id: A0A8F8GKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

465797:I6L31 RS03630
gene id: 465797:I6L31_RS03630
uniprot id: A0A8F8GM01
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

465797:I6L31 RS12515
gene id: 465797:I6L31_RS12515
uniprot id: A0A8F8GMX2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

465797:I6L31 RS11205
gene id: 465797:I6L31_RS11205
uniprot id: A0A8F8GKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

465797:I6L31 RS02705
gene id: 465797:I6L31_RS02705
uniprot id: A0A8F8CVM2
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07035
gene id: 465797:I6L31_RS07035
uniprot id: A0A8F8GMP5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

465797:I6L31 RS07650
gene id: 465797:I6L31_RS07650
uniprot id: A0A8F8CXW5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465797:I6L31 RS03800
gene id: 465797:I6L31_RS03800
uniprot id: A0A8F8GKA3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

465797:I6L31 RS11345
gene id: 465797:I6L31_RS11345
uniprot id: A0A8F8GIT0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

465797:I6L31 RS15170
gene id: 465797:I6L31_RS15170
uniprot id: A0A8F8CPG0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465797:I6L31 RS00690
gene id: 465797:I6L31_RS00690
uniprot id: A0A8F8CUZ5
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

465797:I6L31 RS03340
gene id: 465797:I6L31_RS03340
uniprot id: A0A8F8CTU9
names: Similarity
messages: Belongs to the nitroreductase family.

465797:I6L31 RS02340
gene id: 465797:I6L31_RS02340
uniprot id: A0A8F8CWZ3
names: Similarity
messages: Belongs to the HesB/IscA family.

465797:I6L31 RS00750
gene id: 465797:I6L31_RS00750
uniprot id: A0A8F8CQ56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

465797:I6L31 RS02650
gene id: 465797:I6L31_RS02650
uniprot id: A0A8F8GLU2
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS03785
gene id: 465797:I6L31_RS03785
uniprot id: A0A8F8CW67
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

465797:I6L31 RS07655
gene id: 465797:I6L31_RS07655
uniprot id: A0A8F8GKX7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

465797:I6L31 RS16610
gene id: 465797:I6L31_RS16610
uniprot id: A0A8F8GNG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS02335
gene id: 465797:I6L31_RS02335
uniprot id: A0A8F8CTI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

465797:I6L31 RS00905
gene id: 465797:I6L31_RS00905
uniprot id: A0A8F8CVA1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

465797:I6L31 RS08020
gene id: 465797:I6L31_RS08020
uniprot id: A0A8F8GKZ8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08050
gene id: 465797:I6L31_RS08050
uniprot id: A0A8F8CSY8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

465797:I6L31 RS15205
gene id: 465797:I6L31_RS15205
uniprot id: A0A8F8GJF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS03965
gene id: 465797:I6L31_RS03965
uniprot id: A0A8F8GL75
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS03210
gene id: 465797:I6L31_RS03210
uniprot id: A0A8F8CTT1
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

465797:I6L31 RS07625
gene id: 465797:I6L31_RS07625
uniprot id: A0A8F8CV94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

465797:I6L31 RS08950
gene id: 465797:I6L31_RS08950
uniprot id: A0A8F8CQ49
names: Similarity
messages: Belongs to the FeoA family.

465797:I6L31 RS02970
gene id: 465797:I6L31_RS02970
uniprot id: A0A8F8CVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

465797:I6L31 RS07735
gene id: 465797:I6L31_RS07735
uniprot id: A0A8F8GKY3
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

465797:I6L31 RS11825
gene id: 465797:I6L31_RS11825
uniprot id: A0A8F8CND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

465797:I6L31 RS04985
gene id: 465797:I6L31_RS04985
uniprot id: A0A8F8CWL3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

465797:I6L31 RS03505
gene id: 465797:I6L31_RS03505
uniprot id: A0A8F8CR81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

465797:I6L31 RS13465
gene id: 465797:I6L31_RS13465
uniprot id: A0A8F8GKW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS06490
gene id: 465797:I6L31_RS06490
uniprot id: A0A8F8CY96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

465797:I6L31 RS14115
gene id: 465797:I6L31_RS14115
uniprot id: A0A8F8GJ90
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

465797:I6L31 RS12915
gene id: 465797:I6L31_RS12915
uniprot id: A0A8F8GJW2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

465797:I6L31 RS15645
gene id: 465797:I6L31_RS15645
uniprot id: A0A8F8CQ96
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

465797:I6L31 RS08205
gene id: 465797:I6L31_RS08205
uniprot id: A0A8F8GMW6
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS06130
gene id: 465797:I6L31_RS06130
uniprot id: A0A8F8CX03
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

465797:I6L31 RS00825
gene id: 465797:I6L31_RS00825
uniprot id: A0A8F8CQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

465797:I6L31 RS08290
gene id: 465797:I6L31_RS08290
uniprot id: A0A8F8CT16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

465797:I6L31 RS13350
gene id: 465797:I6L31_RS13350
uniprot id: A0A8F8CRN0
names: Similarity
messages: Belongs to the UPF0234 family.

465797:I6L31 RS14915
gene id: 465797:I6L31_RS14915
uniprot id: A0A8F8CVL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

465797:I6L31 RS08780
gene id: 465797:I6L31_RS08780
uniprot id: A0A8F8CS25
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS04905
gene id: 465797:I6L31_RS04905
uniprot id: A0A8F8CUD1
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS03485
gene id: 465797:I6L31_RS03485
uniprot id: A0A8F8CRK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

465797:I6L31 RS12840
gene id: 465797:I6L31_RS12840
uniprot id: A0A8F8GJV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

465797:I6L31 RS01680
gene id: 465797:I6L31_RS01680
uniprot id: A0A8F8CTA0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

465797:I6L31 RS13015
gene id: 465797:I6L31_RS13015
uniprot id: A0A8F8CPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465797:I6L31 RS05170
gene id: 465797:I6L31_RS05170
uniprot id: A0A8F8GM88
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS07745
gene id: 465797:I6L31_RS07745
uniprot id: A0A8F8GLU4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

465797:I6L31 RS10930
gene id: 465797:I6L31_RS10930
uniprot id: A0A8F8CNW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

465797:I6L31 RS03130
gene id: 465797:I6L31_RS03130
uniprot id: A0A8F8CVX8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465797:I6L31 RS12760
gene id: 465797:I6L31_RS12760
uniprot id: A0A8F8GJV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS12525
gene id: 465797:I6L31_RS12525
uniprot id: A0A8F8GKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

465797:I6L31 RS11895
gene id: 465797:I6L31_RS11895
uniprot id: A0A8F8CP59
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

465797:I6L31 RS05395
gene id: 465797:I6L31_RS05395
uniprot id: A0A8F8CWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS03775
gene id: 465797:I6L31_RS03775
uniprot id: A0A8F8CXF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

465797:I6L31 RS02465
gene id: 465797:I6L31_RS02465
uniprot id: A0A8F8CSS1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS12165
gene id: 465797:I6L31_RS12165
uniprot id: A0A8F8CP84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

465797:I6L31 RS12030
gene id: 465797:I6L31_RS12030
uniprot id: A0A8F8CTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

465797:I6L31 RS14020
gene id: 465797:I6L31_RS14020
uniprot id: A0A8F8CTT4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

465797:I6L31 RS04490
gene id: 465797:I6L31_RS04490
uniprot id: A0A8F8CRW5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

465797:I6L31 RS15120
gene id: 465797:I6L31_RS15120
uniprot id: A0A8F8GJF0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

465797:I6L31 RS13225
gene id: 465797:I6L31_RS13225
uniprot id: A0A8F8CRM0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

465797:I6L31 RS05180
gene id: 465797:I6L31_RS05180
uniprot id: A0A8F8GMK3
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS01380
gene id: 465797:I6L31_RS01380
uniprot id: A0A8F8GJW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

465797:I6L31 RS08305
gene id: 465797:I6L31_RS08305
uniprot id: A0A8F8CSP5
names: Similarity
messages: Belongs to the DEAD box helicase family.

465797:I6L31 RS05085
gene id: 465797:I6L31_RS05085
uniprot id: A0A8F8GLD9
names: Similarity
messages: Belongs to the citrate synthase family.

465797:I6L31 RS18055
gene id: 465797:I6L31_RS18055
uniprot id: A0A8F8GN81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

465797:I6L31 RS07230
gene id: 465797:I6L31_RS07230
uniprot id: A0A8F8CSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

465797:I6L31 RS00735
gene id: 465797:I6L31_RS00735
uniprot id: A0A8F8CQS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

465797:I6L31 RS15795
gene id: 465797:I6L31_RS15795
uniprot id: A0A8F8GKD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

465797:I6L31 RS10430
gene id: 465797:I6L31_RS10430
uniprot id: A0A8F8GKI2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

465797:I6L31 RS07930
gene id: 465797:I6L31_RS07930
uniprot id: A0A8F8GMV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS09325
gene id: 465797:I6L31_RS09325
uniprot id: A0A8F8GIH5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

465797:I6L31 RS12830
gene id: 465797:I6L31_RS12830
uniprot id: A0A8F8GJ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

465797:I6L31 RS08965
gene id: 465797:I6L31_RS08965
uniprot id: A0A8F8CSA3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

465797:I6L31 RS16180
gene id: 465797:I6L31_RS16180
uniprot id: A0A8F8CUQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

465797:I6L31 RS05375
gene id: 465797:I6L31_RS05375
uniprot id: A0A8F8GML2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

465797:I6L31 RS14470
gene id: 465797:I6L31_RS14470
uniprot id: A0A8F8CP88
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS04315
gene id: 465797:I6L31_RS04315
uniprot id: A0A8F8CRU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

465797:I6L31 RS13855
gene id: 465797:I6L31_RS13855
uniprot id: A0A8F8CTR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

465797:I6L31 RS00460
gene id: 465797:I6L31_RS00460
uniprot id: A0A8F8GKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

465797:I6L31 RS10445
gene id: 465797:I6L31_RS10445
uniprot id: A0A8F8CMY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

465797:I6L31 RS05540
gene id: 465797:I6L31_RS05540
uniprot id: A0A8F8GMA6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

465797:I6L31 RS06855
gene id: 465797:I6L31_RS06855
uniprot id: A0A8F8CSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS13810
gene id: 465797:I6L31_RS13810
uniprot id: A0A8F8GL86
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

465797:I6L31 RS12460
gene id: 465797:I6L31_RS12460
uniprot id: A0A8F8CNR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

465797:I6L31 RS15665
gene id: 465797:I6L31_RS15665
uniprot id: A0A8F8CPT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS10145
gene id: 465797:I6L31_RS10145
uniprot id: A0A8F8CTZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

465797:I6L31 RS07145
gene id: 465797:I6L31_RS07145
uniprot id: A0A8F8CSD5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

465797:I6L31 RS10790
gene id: 465797:I6L31_RS10790
uniprot id: A0A8F8CQS7
names: Similarity
messages: Belongs to the peptidase C56 family.

465797:I6L31 RS07275
gene id: 465797:I6L31_RS07275
uniprot id: A0A8F8GMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

465797:I6L31 RS09930
gene id: 465797:I6L31_RS09930
uniprot id: A0A8F8CSR0
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS14030
gene id: 465797:I6L31_RS14030
uniprot id: A0A8F8CTY6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

465797:I6L31 RS01630
gene id: 465797:I6L31_RS01630
uniprot id: A0A8F8GJX8
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS02905
gene id: 465797:I6L31_RS02905
uniprot id: A0A8F8GK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

465797:I6L31 RS07205
gene id: 465797:I6L31_RS07205
uniprot id: A0A8F8CSQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

465797:I6L31 RS03735
gene id: 465797:I6L31_RS03735
uniprot id: A0A8F8CRN3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

465797:I6L31 RS03055
gene id: 465797:I6L31_RS03055
uniprot id: A0A8F8CVW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

465797:I6L31 RS16165
gene id: 465797:I6L31_RS16165
uniprot id: A0A8F8CSJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PDR/VanB family. CntB subfamily.
messages: Binds 1 2Fe-2S cluster.
messages: Composed of an oxygenase subunit and a reductase subunit.
messages: Converts carnitine to trimethylamine and malic semialdehyde.

465797:I6L31 RS05885
gene id: 465797:I6L31_RS05885
uniprot id: A0A8F8CUN6
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS06055
gene id: 465797:I6L31_RS06055
uniprot id: A0A8F8CUQ7
names: Similarity
messages: Belongs to the transposase 8 family.

465797:I6L31 RS09870
gene id: 465797:I6L31_RS09870
uniprot id: A0A8F8CSK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465797:I6L31 RS17365
gene id: 465797:I6L31_RS17365
uniprot id: A0A8F8D020
names: Similarity
messages: Belongs to the GSP E family.

465797:I6L31 RS06525
gene id: 465797:I6L31_RS06525
uniprot id: A0A8F8GMT0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

465797:I6L31 RS13405
gene id: 465797:I6L31_RS13405
uniprot id: A0A8F8CRL9
names: Similarity
messages: Belongs to the YkuD family.

465797:I6L31 RS06450
gene id: 465797:I6L31_RS06450
uniprot id: A0A8F8GMS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

465797:I6L31 RS13820
gene id: 465797:I6L31_RS13820
uniprot id: A0A8F8CPQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

465797:I6L31 RS12950
gene id: 465797:I6L31_RS12950
uniprot id: A0A8F8CNX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

465797:I6L31 RS07540
gene id: 465797:I6L31_RS07540
uniprot id: A0A8F8CZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

465797:I6L31 RS11810
gene id: 465797:I6L31_RS11810
uniprot id: A0A8F8CP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

465797:I6L31 RS00420
gene id: 465797:I6L31_RS00420
uniprot id: A0A8F8CQ90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

465797:I6L31 RS15950
gene id: 465797:I6L31_RS15950
uniprot id: A0A8F8CSH7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

465797:I6L31 RS01260
gene id: 465797:I6L31_RS01260
uniprot id: A0A8F8CQB1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

465797:I6L31 RS12390
gene id: 465797:I6L31_RS12390
uniprot id: A0A8F8CVU0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

465797:I6L31 RS07490
gene id: 465797:I6L31_RS07490
uniprot id: A0A8F8CVQ5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS18215
gene id: 465797:I6L31_RS18215
uniprot id: A0A8F8GLD7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

465797:I6L31 RS15885
gene id: 465797:I6L31_RS15885
uniprot id: A0A8F8GLA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

465797:I6L31 RS07390
gene id: 465797:I6L31_RS07390
uniprot id: A0A8F8CYK9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

465797:I6L31 RS04605
gene id: 465797:I6L31_RS04605
uniprot id: A0A8F8CRK4
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

465797:I6L31 RS10410
gene id: 465797:I6L31_RS10410
uniprot id: A0A8F8GIM6
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

465797:I6L31 RS06615
gene id: 465797:I6L31_RS06615
uniprot id: A0A8F8GLM4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

465797:I6L31 RS11975
gene id: 465797:I6L31_RS11975
uniprot id: A0A8F8GJQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

465797:I6L31 RS05380
gene id: 465797:I6L31_RS05380
uniprot id: A0A8F8GMF1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

465797:I6L31 RS06375
gene id: 465797:I6L31_RS06375
uniprot id: A0A8F8CS47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

465797:I6L31 RS12615
gene id: 465797:I6L31_RS12615
uniprot id: A0A8F8CTK7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

465797:I6L31 RS06610
gene id: 465797:I6L31_RS06610
uniprot id: A0A8F8GMU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

465797:I6L31 RS05980
gene id: 465797:I6L31_RS05980
uniprot id: A0A8F8CUQ7
names: Similarity
messages: Belongs to the transposase 8 family.

465797:I6L31 RS02815
gene id: 465797:I6L31_RS02815
uniprot id: A0A8F8CTN1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465797:I6L31 RS01615
gene id: 465797:I6L31_RS01615
uniprot id: A0A8F8CV99
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

465797:I6L31 RS05000
gene id: 465797:I6L31_RS05000
uniprot id: A0A8F8GM77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

465797:I6L31 RS00695
gene id: 465797:I6L31_RS00695
uniprot id: A0A8F8GMY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS13370
gene id: 465797:I6L31_RS13370
uniprot id: A0A8F8GL61
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465797:I6L31 RS03890
gene id: 465797:I6L31_RS03890
uniprot id: A0A8F8GMC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

465797:I6L31 RS04760
gene id: 465797:I6L31_RS04760
uniprot id: A0A8F8CRH5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

465797:I6L31 RS07185
gene id: 465797:I6L31_RS07185
uniprot id: A0A8F8GLR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

465797:I6L31 RS16185
gene id: 465797:I6L31_RS16185
uniprot id: A0A8F8CSK9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

465797:I6L31 RS02415
gene id: 465797:I6L31_RS02415
uniprot id: A0A8F8CX00
names: Similarity
messages: Belongs to the peptidase S24 family.

465797:I6L31 RS09260
gene id: 465797:I6L31_RS09260
uniprot id: A0A8F8GKH2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS13135
gene id: 465797:I6L31_RS13135
uniprot id: A0A8F8CTM9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

465797:I6L31 RS12935
gene id: 465797:I6L31_RS12935
uniprot id: A0A8F8CTP5
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

465797:I6L31 RS17520
gene id: 465797:I6L31_RS17520
uniprot id: A0A8F8GM59
names: Similarity
messages: Belongs to the XseB family.

465797:I6L31 RS18050
gene id: 465797:I6L31_RS18050
uniprot id: A0A8F8GNE9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

465797:I6L31 RS04140
gene id: 465797:I6L31_RS04140
uniprot id: A0A8F8GM30
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

465797:I6L31 RS02215
gene id: 465797:I6L31_RS02215
uniprot id: A0A8F8GLW4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

465797:I6L31 RS14730
gene id: 465797:I6L31_RS14730
uniprot id: A0A8F8CPZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

465797:I6L31 RS16560
gene id: 465797:I6L31_RS16560
uniprot id: A0A8F8CTE8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

465797:I6L31 RS03980
gene id: 465797:I6L31_RS03980
uniprot id: A0A8F8GM70
names: Function
names: Similarity
messages: Belongs to the GSP L family.
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.

465797:I6L31 RS00835
gene id: 465797:I6L31_RS00835
uniprot id: A0A8F8CQ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

465797:I6L31 RS00680
gene id: 465797:I6L31_RS00680
uniprot id: A0A8F8CSX9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

465797:I6L31 RS04715
gene id: 465797:I6L31_RS04715
uniprot id: A0A8F8GKF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

465797:I6L31 RS12945
gene id: 465797:I6L31_RS12945
uniprot id: A0A8F8CNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

465797:I6L31 RS01885
gene id: 465797:I6L31_RS01885
uniprot id: A0A8F8GLU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

465797:I6L31 RS06500
gene id: 465797:I6L31_RS06500
uniprot id: A0A8F8CX44
names: Similarity
messages: Belongs to the thioredoxin family.

465797:I6L31 RS00555
gene id: 465797:I6L31_RS00555
uniprot id: A0A8F8GLL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS05555
gene id: 465797:I6L31_RS05555
uniprot id: A0A8F8GMG1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

465797:I6L31 RS12890
gene id: 465797:I6L31_RS12890
uniprot id: A0A8F8CTE3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

465797:I6L31 RS12805
gene id: 465797:I6L31_RS12805
uniprot id: A0A8F8CRE5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS03175
gene id: 465797:I6L31_RS03175
uniprot id: A0A8F8CQY5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

465797:I6L31 RS16210
gene id: 465797:I6L31_RS16210
uniprot id: A0A8F8GLG4
names: Similarity
messages: Belongs to the pirin family.

465797:I6L31 RS04055
gene id: 465797:I6L31_RS04055
uniprot id: A0A8F8CQJ3
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

465797:I6L31 RS14085
gene id: 465797:I6L31_RS14085
uniprot id: A0A8F8CPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

465797:I6L31 RS11970
gene id: 465797:I6L31_RS11970
uniprot id: A0A8F8GKM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

465797:I6L31 RS06440
gene id: 465797:I6L31_RS06440
uniprot id: A0A8F8GMF3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

465797:I6L31 RS13495
gene id: 465797:I6L31_RS13495
uniprot id: A0A8F8CTV7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS13800
gene id: 465797:I6L31_RS13800
uniprot id: A0A8F8GKY1
names: Similarity
messages: Belongs to the Rht family.

465797:I6L31 RS05620
gene id: 465797:I6L31_RS05620
uniprot id: A0A8F8GKK5
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

465797:I6L31 RS07405
gene id: 465797:I6L31_RS07405
uniprot id: A0A8F8CV64
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

465797:I6L31 RS03465
gene id: 465797:I6L31_RS03465
uniprot id: A0A8F8GLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

465797:I6L31 RS06460
gene id: 465797:I6L31_RS06460
uniprot id: A0A8F8CSG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

465797:I6L31 RS07825
gene id: 465797:I6L31_RS07825
uniprot id: A0A8F8CXK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

465797:I6L31 RS13245
gene id: 465797:I6L31_RS13245
uniprot id: A0A8F8GL54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

465797:I6L31 RS07170
gene id: 465797:I6L31_RS07170
uniprot id: A0A8F8CV34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

465797:I6L31 RS11445
gene id: 465797:I6L31_RS11445
uniprot id: A0A8F8GKU9
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS11245
gene id: 465797:I6L31_RS11245
uniprot id: A0A8F8CQW3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

465797:I6L31 RS05360
gene id: 465797:I6L31_RS05360
uniprot id: A0A8F8GKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

465797:I6L31 RS08870
gene id: 465797:I6L31_RS08870
uniprot id: A0A8F8CMN6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

465797:I6L31 RS07725
gene id: 465797:I6L31_RS07725
uniprot id: A0A8F8CXJ4
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS08040
gene id: 465797:I6L31_RS08040
uniprot id: A0A8F8GN20
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

465797:I6L31 RS02720
gene id: 465797:I6L31_RS02720
uniprot id: A0A8F8CTM1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

465797:I6L31 RS14360
gene id: 465797:I6L31_RS14360
uniprot id: A0A8F8GJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

465797:I6L31 RS02840
gene id: 465797:I6L31_RS02840
uniprot id: A0A8F8CZ01
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

465797:I6L31 RS01370
gene id: 465797:I6L31_RS01370
uniprot id: A0A8F8CVC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

465797:I6L31 RS15440
gene id: 465797:I6L31_RS15440
uniprot id: A0A8F8CUC2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

465797:I6L31 RS16915
gene id: 465797:I6L31_RS16915
uniprot id: A0A8F8GLG6
names: Subcellular Location Annotation
messages: Cytoplasm

465797:I6L31 RS10735
gene id: 465797:I6L31_RS10735
uniprot id: A0A8F8GKQ8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

465797:I6L31 RS03720
gene id: 465797:I6L31_RS03720
uniprot id: A0A8F8GL60
names: Similarity
messages: Belongs to the peptidase C59 family.

465797:I6L31 RS13010
gene id: 465797:I6L31_RS13010
uniprot id: A0A8F8GKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

465797:I6L31 RS03290
gene id: 465797:I6L31_RS03290
uniprot id: A0A8F8GK71
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

465797:I6L31 RS08330
gene id: 465797:I6L31_RS08330
uniprot id: A0A8F8CXM7
names: Subunit
messages: Homodimer.

465797:I6L31 RS08750
gene id: 465797:I6L31_RS08750
uniprot id: A0A8F8CSD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

465797:I6L31 RS13880
gene id: 465797:I6L31_RS13880
uniprot id: A0A8F8GJ76
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

465797:I6L31 RS11930
gene id: 465797:I6L31_RS11930
uniprot id: A0A8F8CUL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

465797:I6L31 RS11405
gene id: 465797:I6L31_RS11405
uniprot id: A0A8F8CUE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

465797:I6L31 RS15650
gene id: 465797:I6L31_RS15650
uniprot id: A0A8F8CUN5
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS14945
gene id: 465797:I6L31_RS14945
uniprot id: A0A8F8GJE0
names: Similarity
messages: Belongs to the PrpF family.

465797:I6L31 RS14600
gene id: 465797:I6L31_RS14600
uniprot id: A0A8F8CU13
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

465797:I6L31 RS02085
gene id: 465797:I6L31_RS02085
uniprot id: A0A8F8CQK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

465797:I6L31 RS08920
gene id: 465797:I6L31_RS08920
uniprot id: A0A8F8GKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

465797:I6L31 RS10585
gene id: 465797:I6L31_RS10585
uniprot id: A0A8F8GKJ2
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

465797:I6L31 RS01790
gene id: 465797:I6L31_RS01790
uniprot id: A0A8F8GLZ3
names: Subcellular Location Annotation
messages: Membrane

465797:I6L31 RS15480
gene id: 465797:I6L31_RS15480
uniprot id: A0A8F8GLI5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS01475
gene id: 465797:I6L31_RS01475
uniprot id: A0A8F8GLZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS14845
gene id: 465797:I6L31_RS14845
uniprot id: A0A8F8CU44
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

465797:I6L31 RS00450
gene id: 465797:I6L31_RS00450
uniprot id: A0A8F8GJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

465797:I6L31 RS04465
gene id: 465797:I6L31_RS04465
uniprot id: A0A8F8GKE1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

465797:I6L31 RS03155
gene id: 465797:I6L31_RS03155
uniprot id: A0A8F8GM85
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

465797:I6L31 RS05735
gene id: 465797:I6L31_RS05735
uniprot id: A0A8F8GMN3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

465797:I6L31 RS11545
gene id: 465797:I6L31_RS11545
uniprot id: A0A8F8CNA7
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

465797:I6L31 RS10890
gene id: 465797:I6L31_RS10890
uniprot id: A0A8F8CSW2
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

465797:I6L31 RS03620
gene id: 465797:I6L31_RS03620
uniprot id: A0A8F8CTX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

465797:I6L31 RS10185
gene id: 465797:I6L31_RS10185
uniprot id: A0A8F8GKM2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

465797:I6L31 RS08320
gene id: 465797:I6L31_RS08320
uniprot id: A0A8F8CVH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.