458817:SHAL RS08975
gene id: 458817:SHAL_RS08975
uniprot id: B0TQ16
names: Similarity
messages: Belongs to the heat shock protein 70 family.

458817:SHAL RS15795
gene id: 458817:SHAL_RS15795
uniprot id: B0TPF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

458817:SHAL RS05300
gene id: 458817:SHAL_RS05300
uniprot id: B0TIR7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

458817:SHAL RS15435
gene id: 458817:SHAL_RS15435
uniprot id: B0TP88
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

458817:SHAL RS21320
gene id: 458817:SHAL_RS21320
uniprot id: B0TM01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

458817:SHAL RS00005
gene id: 458817:SHAL_RS00005
uniprot id: B0TLA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

458817:SHAL RS00245
gene id: 458817:SHAL_RS00245
uniprot id: B0TLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

458817:SHAL RS01460
gene id: 458817:SHAL_RS01460
uniprot id: B0TNW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

458817:SHAL RS03400
gene id: 458817:SHAL_RS03400
uniprot id: B0TSR4
names: Similarity
messages: Belongs to the aldose epimerase family.

458817:SHAL RS02730
gene id: 458817:SHAL_RS02730
uniprot id: B0TRE0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS15305
gene id: 458817:SHAL_RS15305
uniprot id: B0TNJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS13715
gene id: 458817:SHAL_RS13715
uniprot id: B0TKZ3
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

458817:SHAL RS14840
gene id: 458817:SHAL_RS14840
uniprot id: B0TMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

458817:SHAL RS18995
gene id: 458817:SHAL_RS18995
uniprot id: B0TUU6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

458817:SHAL RS17195
gene id: 458817:SHAL_RS17195
uniprot id: B0TRV3
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS12415
gene id: 458817:SHAL_RS12415
uniprot id: B0TJ02
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS18285
gene id: 458817:SHAL_RS18285
uniprot id: B0TTD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

458817:SHAL RS16165
gene id: 458817:SHAL_RS16165
uniprot id: B0TQ88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

458817:SHAL RS13490
gene id: 458817:SHAL_RS13490
uniprot id: B0TKU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS20130
gene id: 458817:SHAL_RS20130
uniprot id: B0TJ33
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

458817:SHAL RS13535
gene id: 458817:SHAL_RS13535
uniprot id: B0TKV6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

458817:SHAL RS12045
gene id: 458817:SHAL_RS12045
uniprot id: B0TVI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

458817:SHAL RS19590
gene id: 458817:SHAL_RS19590
uniprot id: B0TVM7
names: Similarity
messages: Belongs to the PhoH family.

458817:SHAL RS16155
gene id: 458817:SHAL_RS16155
uniprot id: B0TQ86
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

458817:SHAL RS01150
gene id: 458817:SHAL_RS01150
uniprot id: B0TNQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS11305
gene id: 458817:SHAL_RS11305
uniprot id: B0TUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS03680
gene id: 458817:SHAL_RS03680
uniprot id: B0TSW8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS06930
gene id: 458817:SHAL_RS06930
uniprot id: B0TLG4
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

458817:SHAL RS16560
gene id: 458817:SHAL_RS16560
uniprot id: B0TR27
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

458817:SHAL RS01715
gene id: 458817:SHAL_RS01715
uniprot id: B0TPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

458817:SHAL RS16950
gene id: 458817:SHAL_RS16950
uniprot id: B0TRQ6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

458817:SHAL RS02095
gene id: 458817:SHAL_RS02095
uniprot id: B0TQJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS00340
gene id: 458817:SHAL_RS00340
uniprot id: B0TM50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

458817:SHAL RS21605
gene id: 458817:SHAL_RS21605
uniprot id: B0TMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS08090
gene id: 458817:SHAL_RS08090
uniprot id: B0TND7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

458817:SHAL RS02320
gene id: 458817:SHAL_RS02320
uniprot id: B0TQP2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

458817:SHAL RS03860
gene id: 458817:SHAL_RS03860
uniprot id: B0TTI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

458817:SHAL RS16200
gene id: 458817:SHAL_RS16200
uniprot id: B0TQ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

458817:SHAL RS02370
gene id: 458817:SHAL_RS02370
uniprot id: B0TQP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

458817:SHAL RS06760
gene id: 458817:SHAL_RS06760
uniprot id: B0TKT0
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

458817:SHAL RS05430
gene id: 458817:SHAL_RS05430
uniprot id: B0TIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS15290
gene id: 458817:SHAL_RS15290
uniprot id: B0TNJ2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS10065
gene id: 458817:SHAL_RS10065
uniprot id: B0TSC1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS14010
gene id: 458817:SHAL_RS14010
uniprot id: B0TL53
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS00250
gene id: 458817:SHAL_RS00250
uniprot id: B0TLE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

458817:SHAL RS13805
gene id: 458817:SHAL_RS13805
uniprot id: B0TL11
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS11805
gene id: 458817:SHAL_RS11805
uniprot id: B0TVD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

458817:SHAL RS11845
gene id: 458817:SHAL_RS11845
uniprot id: B0TVE5
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

458817:SHAL RS18905
gene id: 458817:SHAL_RS18905
uniprot id: B0TU84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

458817:SHAL RS15880
gene id: 458817:SHAL_RS15880
uniprot id: B0TQ29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS21340
gene id: 458817:SHAL_RS21340
uniprot id: B0TM05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

458817:SHAL RS05500
gene id: 458817:SHAL_RS05500
uniprot id: B0TIV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

458817:SHAL RS10635
gene id: 458817:SHAL_RS10635
uniprot id: B0TT36
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

458817:SHAL RS07015
gene id: 458817:SHAL_RS07015
uniprot id: B0TLI0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS06040
gene id: 458817:SHAL_RS06040
uniprot id: B0TJW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

458817:SHAL RS22055
gene id: 458817:SHAL_RS22055
uniprot id: B0TPK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

458817:SHAL RS03245
gene id: 458817:SHAL_RS03245
uniprot id: B0TS73
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

458817:SHAL RS13525
gene id: 458817:SHAL_RS13525
uniprot id: B0TKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

458817:SHAL RS22245
gene id: 458817:SHAL_RS22245
uniprot id: B0TQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

458817:SHAL RS09315
gene id: 458817:SHAL_RS09315
uniprot id: B0TQW7
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS00780
gene id: 458817:SHAL_RS00780
uniprot id: B0TN17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

458817:SHAL RS08885
gene id: 458817:SHAL_RS08885
uniprot id: B0TPZ8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

458817:SHAL RS21905
gene id: 458817:SHAL_RS21905
uniprot id: B0TNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

458817:SHAL RS16825
gene id: 458817:SHAL_RS16825
uniprot id: B0TR63
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

458817:SHAL RS12260
gene id: 458817:SHAL_RS12260
uniprot id: B0TIX1
names: Similarity
messages: Belongs to the peptidase S16 family.

458817:SHAL RS15400
gene id: 458817:SHAL_RS15400
uniprot id: B0TP81
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS18965
gene id: 458817:SHAL_RS18965
uniprot id: B0TU96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS01270
gene id: 458817:SHAL_RS01270
uniprot id: B0TNS5
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS06470
gene id: 458817:SHAL_RS06470
uniprot id: B0TKM6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

458817:SHAL RS21520
gene id: 458817:SHAL_RS21520
uniprot id: B0TMV6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

458817:SHAL RS10140
gene id: 458817:SHAL_RS10140
uniprot id: B0TSD1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS12265
gene id: 458817:SHAL_RS12265
uniprot id: B0TIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

458817:SHAL RS07550
gene id: 458817:SHAL_RS07550
uniprot id: B0TMG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

458817:SHAL RS20315
gene id: 458817:SHAL_RS20315
uniprot id: B0TJQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

458817:SHAL RS08075
gene id: 458817:SHAL_RS08075
uniprot id: B0TND4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

458817:SHAL RS14000
gene id: 458817:SHAL_RS14000
uniprot id: B0TL51
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08725
gene id: 458817:SHAL_RS08725
uniprot id: B0TPX3
names: Similarity
messages: Belongs to the peptidase S9A family.

458817:SHAL RS05110
gene id: 458817:SHAL_RS05110
uniprot id: B0TIN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

458817:SHAL RS20065
gene id: 458817:SHAL_RS20065
uniprot id: B0TJ25
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

458817:SHAL RS14275
gene id: 458817:SHAL_RS14275
uniprot id: B0TLT5
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS13295
gene id: 458817:SHAL_RS13295
uniprot id: B0TK92
names: Similarity
messages: Belongs to the DapA family.

458817:SHAL RS01670
gene id: 458817:SHAL_RS01670
uniprot id: B0TPN5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS00065
gene id: 458817:SHAL_RS00065
uniprot id: B0TLB6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

458817:SHAL RS09335
gene id: 458817:SHAL_RS09335
uniprot id: B0TQX2
names: Similarity
messages: Belongs to the CvfB family.

458817:SHAL RS05495
gene id: 458817:SHAL_RS05495
uniprot id: B0TIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

458817:SHAL RS21585
gene id: 458817:SHAL_RS21585
uniprot id: B0TMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS15620
gene id: 458817:SHAL_RS15620
uniprot id: B0TPC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS08235
gene id: 458817:SHAL_RS08235
uniprot id: B0TNZ7
names: Subcellular Location Annotation
messages: Cell inner membrane

458817:SHAL RS14670
gene id: 458817:SHAL_RS14670
uniprot id: B0TMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine racemase family. Bsr subfamily.
messages: Periplasm

458817:SHAL RS00115
gene id: 458817:SHAL_RS00115
uniprot id: B0TLC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

458817:SHAL RS15775
gene id: 458817:SHAL_RS15775
uniprot id: B0TPF3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

458817:SHAL RS19525
gene id: 458817:SHAL_RS19525
uniprot id: B0TVL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

458817:SHAL RS21940
gene id: 458817:SHAL_RS21940
uniprot id: B0TPH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

458817:SHAL RS17695
gene id: 458817:SHAL_RS17695
uniprot id: B0TSK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorD/DmsD family. TorD subfamily.
messages: Cytoplasm
messages: Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.

458817:SHAL RS12455
gene id: 458817:SHAL_RS12455
uniprot id: B0TJE9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

458817:SHAL RS14705
gene id: 458817:SHAL_RS14705
uniprot id: B0TMN1
names: Subcellular Location Annotation
messages: Secreted

458817:SHAL RS02935
gene id: 458817:SHAL_RS02935
uniprot id: B0TS18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

458817:SHAL RS00735
gene id: 458817:SHAL_RS00735
uniprot id: B0TN08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

458817:SHAL RS15785
gene id: 458817:SHAL_RS15785
uniprot id: B0TPF6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

458817:SHAL RS21275
gene id: 458817:SHAL_RS21275
uniprot id: B0TLZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

458817:SHAL RS18920
gene id: 458817:SHAL_RS18920
uniprot id: B0TU87
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

458817:SHAL RS20390
gene id: 458817:SHAL_RS20390
uniprot id: B0TJR7
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS02405
gene id: 458817:SHAL_RS02405
uniprot id: B0TQQ4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

458817:SHAL RS10915
gene id: 458817:SHAL_RS10915
uniprot id: B0TTT0
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

458817:SHAL RS21910
gene id: 458817:SHAL_RS21910
uniprot id: B0TPH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

458817:SHAL RS15195
gene id: 458817:SHAL_RS15195
uniprot id: B0TNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

458817:SHAL RS00130
gene id: 458817:SHAL_RS00130
uniprot id: B0TLC9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

458817:SHAL RS17855
gene id: 458817:SHAL_RS17855
uniprot id: B0TSN9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

458817:SHAL RS19875
gene id: 458817:SHAL_RS19875
uniprot id: B0TVT7
names: Similarity
messages: Belongs to the GSP E family.

458817:SHAL RS15215
gene id: 458817:SHAL_RS15215
uniprot id: B0TNH7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

458817:SHAL RS00845
gene id: 458817:SHAL_RS00845
uniprot id: B0TN30
names: Similarity
messages: Belongs to the RutC family.

458817:SHAL RS05105
gene id: 458817:SHAL_RS05105
uniprot id: B0TIN1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS03935
gene id: 458817:SHAL_RS03935
uniprot id: B0TTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS00740
gene id: 458817:SHAL_RS00740
uniprot id: B0TN09
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

458817:SHAL RS18005
gene id: 458817:SHAL_RS18005
uniprot id: B0TT84
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS02955
gene id: 458817:SHAL_RS02955
uniprot id: B0TS22
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

458817:SHAL RS11860
gene id: 458817:SHAL_RS11860
uniprot id: B0TVE8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS20170
gene id: 458817:SHAL_RS20170
uniprot id: B0TJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

458817:SHAL RS16300
gene id: 458817:SHAL_RS16300
uniprot id: B0TQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

458817:SHAL RS14550
gene id: 458817:SHAL_RS14550
uniprot id: B0TMJ9
names: Similarity
messages: Belongs to the transglycosylase Slt family.

458817:SHAL RS00630
gene id: 458817:SHAL_RS00630
uniprot id: B0TMA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

458817:SHAL RS05125
gene id: 458817:SHAL_RS05125
uniprot id: B0TIN4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

458817:SHAL RS08115
gene id: 458817:SHAL_RS08115
uniprot id: B0TNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

458817:SHAL RS21850
gene id: 458817:SHAL_RS21850
uniprot id: B0TNM9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

458817:SHAL RS16645
gene id: 458817:SHAL_RS16645
uniprot id: B0TR34
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

458817:SHAL RS15600
gene id: 458817:SHAL_RS15600
uniprot id: B0TPB9
names: Similarity
messages: Belongs to the DEAD box helicase family.

458817:SHAL RS21025
gene id: 458817:SHAL_RS21025
uniprot id: B0TL65
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

458817:SHAL RS21250
gene id: 458817:SHAL_RS21250
uniprot id: B0TLY7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

458817:SHAL RS19730
gene id: 458817:SHAL_RS19730
uniprot id: B0TVQ8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

458817:SHAL RS21050
gene id: 458817:SHAL_RS21050
uniprot id: B0TL70
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

458817:SHAL RS03435
gene id: 458817:SHAL_RS03435
uniprot id: B0TSS1
names: Similarity
messages: Belongs to the CutA family.

458817:SHAL RS04620
gene id: 458817:SHAL_RS04620
uniprot id: B0TUI1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

458817:SHAL RS02905
gene id: 458817:SHAL_RS02905
uniprot id: B0TS12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

458817:SHAL RS06260
gene id: 458817:SHAL_RS06260
uniprot id: B0TK09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

458817:SHAL RS16510
gene id: 458817:SHAL_RS16510
uniprot id: B0TR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

458817:SHAL RS09405
gene id: 458817:SHAL_RS09405
uniprot id: B0TQY6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

458817:SHAL RS21630
gene id: 458817:SHAL_RS21630
uniprot id: B0TMX8
names: Similarity
messages: Belongs to the HSP15 family.

458817:SHAL RS12465
gene id: 458817:SHAL_RS12465
uniprot id: B0TJF1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

458817:SHAL RS02265
gene id: 458817:SHAL_RS02265
uniprot id: B0TQN1
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

458817:SHAL RS14145
gene id: 458817:SHAL_RS14145
uniprot id: B0TLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS10805
gene id: 458817:SHAL_RS10805
uniprot id: B0TTR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

458817:SHAL RS13750
gene id: 458817:SHAL_RS13750
uniprot id: B0TL00
names: Similarity
messages: Belongs to the DSD1 family.

458817:SHAL RS17010
gene id: 458817:SHAL_RS17010
uniprot id: B0TRR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

458817:SHAL RS08940
gene id: 458817:SHAL_RS08940
uniprot id: B0TQ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

458817:SHAL RS03605
gene id: 458817:SHAL_RS03605
uniprot id: B0TSV3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

458817:SHAL RS06150
gene id: 458817:SHAL_RS06150
uniprot id: B0TJY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

458817:SHAL RS07360
gene id: 458817:SHAL_RS07360
uniprot id: B0TMC7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

458817:SHAL RS12680
gene id: 458817:SHAL_RS12680
uniprot id: B0TJJ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS16050
gene id: 458817:SHAL_RS16050
uniprot id: B0TQ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

458817:SHAL RS10600
gene id: 458817:SHAL_RS10600
uniprot id: B0TT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

458817:SHAL RS11500
gene id: 458817:SHAL_RS11500
uniprot id: B0TUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

458817:SHAL RS08275
gene id: 458817:SHAL_RS08275
uniprot id: B0TP05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

458817:SHAL RS16245
gene id: 458817:SHAL_RS16245
uniprot id: B0TQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

458817:SHAL RS07635
gene id: 458817:SHAL_RS07635
uniprot id: B0TMI2
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS04665
gene id: 458817:SHAL_RS04665
uniprot id: B0TV52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

458817:SHAL RS14730
gene id: 458817:SHAL_RS14730
uniprot id: B0TMN6
names: Similarity
messages: Belongs to the peptidase M17 family.

458817:SHAL RS17810
gene id: 458817:SHAL_RS17810
uniprot id: B0TSN0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS13695
gene id: 458817:SHAL_RS13695
uniprot id: B0TKY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

458817:SHAL RS01450
gene id: 458817:SHAL_RS01450
uniprot id: B0TNW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

458817:SHAL RS13415
gene id: 458817:SHAL_RS13415
uniprot id: B0TKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

458817:SHAL RS05325
gene id: 458817:SHAL_RS05325
uniprot id: B0TIS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

458817:SHAL RS16695
gene id: 458817:SHAL_RS16695
uniprot id: B0TR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

458817:SHAL RS21310
gene id: 458817:SHAL_RS21310
uniprot id: B0TLZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

458817:SHAL RS00790
gene id: 458817:SHAL_RS00790
uniprot id: B0TN19
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

458817:SHAL RS15310
gene id: 458817:SHAL_RS15310
uniprot id: B0TNJ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS00770
gene id: 458817:SHAL_RS00770
uniprot id: B0TN15
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS16220
gene id: 458817:SHAL_RS16220
uniprot id: B0TQ99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

458817:SHAL RS12105
gene id: 458817:SHAL_RS12105
uniprot id: B0TVJ6
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS21290
gene id: 458817:SHAL_RS21290
uniprot id: B0TLZ5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

458817:SHAL RS20325
gene id: 458817:SHAL_RS20325
uniprot id: B0TJQ4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS16340
gene id: 458817:SHAL_RS16340
uniprot id: B0TQC1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

458817:SHAL RS20875
gene id: 458817:SHAL_RS20875
uniprot id: B0TKJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS03350
gene id: 458817:SHAL_RS03350
uniprot id: B0TSQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

458817:SHAL RS20685
gene id: 458817:SHAL_RS20685
uniprot id: B0TKF9
names: Similarity
messages: Belongs to the peptidase S9C family.

458817:SHAL RS13885
gene id: 458817:SHAL_RS13885
uniprot id: B0TL29
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

458817:SHAL RS14870
gene id: 458817:SHAL_RS14870
uniprot id: B0TMR2
names: Similarity
messages: Belongs to the HIBADH-related family.

458817:SHAL RS08805
gene id: 458817:SHAL_RS08805
uniprot id: B0TPY2
names: Subunit
messages: Monomer.

458817:SHAL RS01720
gene id: 458817:SHAL_RS01720
uniprot id: B0TPP5
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS02495
gene id: 458817:SHAL_RS02495
uniprot id: B0TR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS14200
gene id: 458817:SHAL_RS14200
uniprot id: B0TLS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

458817:SHAL RS09500
gene id: 458817:SHAL_RS09500
uniprot id: B0TRI1
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

458817:SHAL RS21445
gene id: 458817:SHAL_RS21445
uniprot id: B0TM14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

458817:SHAL RS01320
gene id: 458817:SHAL_RS01320
uniprot id: B0TNT4
names: Similarity
messages: Belongs to the FGGY kinase family.

458817:SHAL RS17995
gene id: 458817:SHAL_RS17995
uniprot id: B0TT82
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS05490
gene id: 458817:SHAL_RS05490
uniprot id: B0TIV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

458817:SHAL RS02285
gene id: 458817:SHAL_RS02285
uniprot id: B0TQN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

458817:SHAL RS05640
gene id: 458817:SHAL_RS05640
uniprot id: B0TJ89
names: Similarity
messages: Belongs to the TrpR family.

458817:SHAL RS02425
gene id: 458817:SHAL_RS02425
uniprot id: B0TQQ8
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

458817:SHAL RS07495
gene id: 458817:SHAL_RS07495
uniprot id: B0TMF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

458817:SHAL RS05695
gene id: 458817:SHAL_RS05695
uniprot id: B0TJA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

458817:SHAL RS06140
gene id: 458817:SHAL_RS06140
uniprot id: B0TJY7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

458817:SHAL RS20190
gene id: 458817:SHAL_RS20190
uniprot id: B0TJ45
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS14560
gene id: 458817:SHAL_RS14560
uniprot id: B0TMK2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

458817:SHAL RS05945
gene id: 458817:SHAL_RS05945
uniprot id: B0TJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

458817:SHAL RS06245
gene id: 458817:SHAL_RS06245
uniprot id: B0TK06
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

458817:SHAL RS02290
gene id: 458817:SHAL_RS02290
uniprot id: B0TQN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

458817:SHAL RS02215
gene id: 458817:SHAL_RS02215
uniprot id: B0TQM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS21315
gene id: 458817:SHAL_RS21315
uniprot id: B0TM00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

458817:SHAL RS12685
gene id: 458817:SHAL_RS12685
uniprot id: B0TJJ7
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

458817:SHAL RS09980
gene id: 458817:SHAL_RS09980
uniprot id: B0TSB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

458817:SHAL RS12540
gene id: 458817:SHAL_RS12540
uniprot id: B0TJG8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

458817:SHAL RS14140
gene id: 458817:SHAL_RS14140
uniprot id: B0TLQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS07485
gene id: 458817:SHAL_RS07485
uniprot id: B0TMF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

458817:SHAL RS15300
gene id: 458817:SHAL_RS15300
uniprot id: B0TNJ4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

458817:SHAL RS18365
gene id: 458817:SHAL_RS18365
uniprot id: B0TTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

458817:SHAL RS03060
gene id: 458817:SHAL_RS03060
uniprot id: B0TS37
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

458817:SHAL RS00805
gene id: 458817:SHAL_RS00805
uniprot id: B0TN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

458817:SHAL RS07075
gene id: 458817:SHAL_RS07075
uniprot id: B0TLJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

458817:SHAL RS01005
gene id: 458817:SHAL_RS01005
uniprot id: B0TN63
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

458817:SHAL RS01800
gene id: 458817:SHAL_RS01800
uniprot id: B0TPR1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

458817:SHAL RS01095
gene id: 458817:SHAL_RS01095
uniprot id: B0TN81
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

458817:SHAL RS17885
gene id: 458817:SHAL_RS17885
uniprot id: B0TSP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

458817:SHAL RS05825
gene id: 458817:SHAL_RS05825
uniprot id: B0TJC6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

458817:SHAL RS07525
gene id: 458817:SHAL_RS07525
uniprot id: B0TMF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

458817:SHAL RS04710
gene id: 458817:SHAL_RS04710
uniprot id: B0TV61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

458817:SHAL RS12555
gene id: 458817:SHAL_RS12555
uniprot id: B0TJH1
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

458817:SHAL RS09600
gene id: 458817:SHAL_RS09600
uniprot id: B0TRK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

458817:SHAL RS20360
gene id: 458817:SHAL_RS20360
uniprot id: B0TJR1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS10565
gene id: 458817:SHAL_RS10565
uniprot id: B0TT22
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

458817:SHAL RS01420
gene id: 458817:SHAL_RS01420
uniprot id: B0TNV5
names: Similarity
messages: Belongs to the UPF0319 family.

458817:SHAL RS01725
gene id: 458817:SHAL_RS01725
uniprot id: B0TPP6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

458817:SHAL RS01965
gene id: 458817:SHAL_RS01965
uniprot id: B0TPU3
names: Similarity
messages: Belongs to the RutC family.

458817:SHAL RS11575
gene id: 458817:SHAL_RS11575
uniprot id: B0TUP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

458817:SHAL RS18235
gene id: 458817:SHAL_RS18235
uniprot id: B0TTC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

458817:SHAL RS19150
gene id: 458817:SHAL_RS19150
uniprot id: B0TUX7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

458817:SHAL RS05200
gene id: 458817:SHAL_RS05200
uniprot id: B0TIP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

458817:SHAL RS20845
gene id: 458817:SHAL_RS20845
uniprot id: B0TKJ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS00945
gene id: 458817:SHAL_RS00945
uniprot id: B0TN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

458817:SHAL RS21590
gene id: 458817:SHAL_RS21590
uniprot id: B0TMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS01850
gene id: 458817:SHAL_RS01850
uniprot id: B0TPS0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

458817:SHAL RS05810
gene id: 458817:SHAL_RS05810
uniprot id: B0TJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS20570
gene id: 458817:SHAL_RS20570
uniprot id: B0TKD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS10840
gene id: 458817:SHAL_RS10840
uniprot id: B0TTR9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

458817:SHAL RS18565
gene id: 458817:SHAL_RS18565
uniprot id: B0TU22
names: Similarity
messages: Belongs to the DEAD box helicase family.

458817:SHAL RS05750
gene id: 458817:SHAL_RS05750
uniprot id: B0TJB1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

458817:SHAL RS21420
gene id: 458817:SHAL_RS21420
uniprot id: B0TM21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

458817:SHAL RS21730
gene id: 458817:SHAL_RS21730
uniprot id: B0TNK4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

458817:SHAL RS07345
gene id: 458817:SHAL_RS07345
uniprot id: B0TMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

458817:SHAL RS09700
gene id: 458817:SHAL_RS09700
uniprot id: B0TRM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

458817:SHAL RS21255
gene id: 458817:SHAL_RS21255
uniprot id: B0TLY8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

458817:SHAL RS13645
gene id: 458817:SHAL_RS13645
uniprot id: B0TKX8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

458817:SHAL RS18680
gene id: 458817:SHAL_RS18680
uniprot id: B0TU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

458817:SHAL RS15130
gene id: 458817:SHAL_RS15130
uniprot id: B0TNG0
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

458817:SHAL RS13360
gene id: 458817:SHAL_RS13360
uniprot id: B0TKA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

458817:SHAL RS15730
gene id: 458817:SHAL_RS15730
uniprot id: B0TPE4
names: Similarity
messages: Belongs to the group II decarboxylase family.

458817:SHAL RS02630
gene id: 458817:SHAL_RS02630
uniprot id: B0TRC0
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

458817:SHAL RS05930
gene id: 458817:SHAL_RS05930
uniprot id: B0TJE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS12120
gene id: 458817:SHAL_RS12120
uniprot id: B0TVJ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS15565
gene id: 458817:SHAL_RS15565
uniprot id: B0TPB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS17515
gene id: 458817:SHAL_RS17515
uniprot id: B0TSH1
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

458817:SHAL RS08945
gene id: 458817:SHAL_RS08945
uniprot id: B0TQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

458817:SHAL RS15255
gene id: 458817:SHAL_RS15255
uniprot id: B0TNI5
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

458817:SHAL RS07515
gene id: 458817:SHAL_RS07515
uniprot id: B0TMF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

458817:SHAL RS15370
gene id: 458817:SHAL_RS15370
uniprot id: B0TP75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

458817:SHAL RS22260
gene id: 458817:SHAL_RS22260
uniprot id: B0TQF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

458817:SHAL RS20415
gene id: 458817:SHAL_RS20415
uniprot id: B0TJS2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

458817:SHAL RS02080
gene id: 458817:SHAL_RS02080
uniprot id: B0TQJ4
names: Similarity
messages: Belongs to the UxaA family.

458817:SHAL RS06050
gene id: 458817:SHAL_RS06050
uniprot id: B0TJW9
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

458817:SHAL RS09655
gene id: 458817:SHAL_RS09655
uniprot id: B0TRL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

458817:SHAL RS11705
gene id: 458817:SHAL_RS11705
uniprot id: B0TUS4
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

458817:SHAL RS08750
gene id: 458817:SHAL_RS08750
uniprot id: B0TPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

458817:SHAL RS15230
gene id: 458817:SHAL_RS15230
uniprot id: B0TNI0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

458817:SHAL RS06500
gene id: 458817:SHAL_RS06500
uniprot id: B0TKN2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

458817:SHAL RS06250
gene id: 458817:SHAL_RS06250
uniprot id: B0TK07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

458817:SHAL RS02160
gene id: 458817:SHAL_RS02160
uniprot id: B0TQL0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

458817:SHAL RS07615
gene id: 458817:SHAL_RS07615
uniprot id: B0TMH8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS17895
gene id: 458817:SHAL_RS17895
uniprot id: B0TSP7
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

458817:SHAL RS10890
gene id: 458817:SHAL_RS10890
uniprot id: B0TTS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS21140
gene id: 458817:SHAL_RS21140
uniprot id: B0TL88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

458817:SHAL RS08385
gene id: 458817:SHAL_RS08385
uniprot id: B0TP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

458817:SHAL RS14945
gene id: 458817:SHAL_RS14945
uniprot id: B0TMS7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS08755
gene id: 458817:SHAL_RS08755
uniprot id: B0TPX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

458817:SHAL RS12915
gene id: 458817:SHAL_RS12915
uniprot id: B0TJP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS13205
gene id: 458817:SHAL_RS13205
uniprot id: B0TK77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

458817:SHAL RS15055
gene id: 458817:SHAL_RS15055
uniprot id: B0TMU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS03375
gene id: 458817:SHAL_RS03375
uniprot id: B0TSR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

458817:SHAL RS07035
gene id: 458817:SHAL_RS07035
uniprot id: B0TLI4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

458817:SHAL RS04975
gene id: 458817:SHAL_RS04975
uniprot id: B0TVB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS17685
gene id: 458817:SHAL_RS17685
uniprot id: B0TSK6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS14680
gene id: 458817:SHAL_RS14680
uniprot id: B0TMM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

458817:SHAL RS07170
gene id: 458817:SHAL_RS07170
uniprot id: B0TLK9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

458817:SHAL RS04095
gene id: 458817:SHAL_RS04095
uniprot id: B0TTN2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

458817:SHAL RS21305
gene id: 458817:SHAL_RS21305
uniprot id: B0TLZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

458817:SHAL RS04385
gene id: 458817:SHAL_RS04385
uniprot id: B0TUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

458817:SHAL RS16285
gene id: 458817:SHAL_RS16285
uniprot id: B0TQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

458817:SHAL RS03515
gene id: 458817:SHAL_RS03515
uniprot id: B0TST6
names: Similarity
messages: Belongs to the RutC family.

458817:SHAL RS01110
gene id: 458817:SHAL_RS01110
uniprot id: B0TNP3
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS14885
gene id: 458817:SHAL_RS14885
uniprot id: B0TMR5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS11220
gene id: 458817:SHAL_RS11220
uniprot id: B0TTZ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS03705
gene id: 458817:SHAL_RS03705
uniprot id: B0TSX3
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

458817:SHAL RS05380
gene id: 458817:SHAL_RS05380
uniprot id: B0TIT3
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

458817:SHAL RS14635
gene id: 458817:SHAL_RS14635
uniprot id: B0TML7
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS06505
gene id: 458817:SHAL_RS06505
uniprot id: B0TKN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS09525
gene id: 458817:SHAL_RS09525
uniprot id: B0TRI6
names: Similarity
messages: Belongs to the UPF0260 family.

458817:SHAL RS14260
gene id: 458817:SHAL_RS14260
uniprot id: B0TLT2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

458817:SHAL RS01615
gene id: 458817:SHAL_RS01615
uniprot id: B0TPM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

458817:SHAL RS02700
gene id: 458817:SHAL_RS02700
uniprot id: B0TRD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS19220
gene id: 458817:SHAL_RS19220
uniprot id: B0TUZ1
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS12305
gene id: 458817:SHAL_RS12305
uniprot id: B0TIY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

458817:SHAL RS03715
gene id: 458817:SHAL_RS03715
uniprot id: B0TSX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS04330
gene id: 458817:SHAL_RS04330
uniprot id: B0TUC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

458817:SHAL RS14265
gene id: 458817:SHAL_RS14265
uniprot id: B0TLT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS06920
gene id: 458817:SHAL_RS06920
uniprot id: B0TLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

458817:SHAL RS07475
gene id: 458817:SHAL_RS07475
uniprot id: B0TME9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS10325
gene id: 458817:SHAL_RS10325
uniprot id: B0TSY7
names: Similarity
messages: Belongs to the GST superfamily.

458817:SHAL RS05025
gene id: 458817:SHAL_RS05025
uniprot id: B0TVC2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS14525
gene id: 458817:SHAL_RS14525
uniprot id: B0TLY2
names: Similarity
messages: Belongs to the group II decarboxylase family.

458817:SHAL RS02275
gene id: 458817:SHAL_RS02275
uniprot id: B0TQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

458817:SHAL RS20350
gene id: 458817:SHAL_RS20350
uniprot id: B0TJQ9
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS10210
gene id: 458817:SHAL_RS10210
uniprot id: B0TSE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

458817:SHAL RS08715
gene id: 458817:SHAL_RS08715
uniprot id: B0TPX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

458817:SHAL RS16385
gene id: 458817:SHAL_RS16385
uniprot id: B0TQD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

458817:SHAL RS12130
gene id: 458817:SHAL_RS12130
uniprot id: B0TVK1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

458817:SHAL RS15225
gene id: 458817:SHAL_RS15225
uniprot id: B0TNH9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

458817:SHAL RS12410
gene id: 458817:SHAL_RS12410
uniprot id: B0TJ01
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

458817:SHAL RS00625
gene id: 458817:SHAL_RS00625
uniprot id: B0TMA6
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

458817:SHAL RS18990
gene id: 458817:SHAL_RS18990
uniprot id: B0TUU5
names: Similarity
messages: Belongs to the peptidase S46 family.

458817:SHAL RS20245
gene id: 458817:SHAL_RS20245
uniprot id: B0TJ57
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

458817:SHAL RS13755
gene id: 458817:SHAL_RS13755
uniprot id: B0TL01
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS13955
gene id: 458817:SHAL_RS13955
uniprot id: B0TL42
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

458817:SHAL RS15060
gene id: 458817:SHAL_RS15060
uniprot id: B0TMV0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS03665
gene id: 458817:SHAL_RS03665
uniprot id: B0TSW5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

458817:SHAL RS08520
gene id: 458817:SHAL_RS08520
uniprot id: B0TP53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS20230
gene id: 458817:SHAL_RS20230
uniprot id: B0TJ54
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

458817:SHAL RS07085
gene id: 458817:SHAL_RS07085
uniprot id: B0TLJ4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

458817:SHAL RS06285
gene id: 458817:SHAL_RS06285
uniprot id: B0TK14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

458817:SHAL RS18985
gene id: 458817:SHAL_RS18985
uniprot id: B0TUU4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

458817:SHAL RS09680
gene id: 458817:SHAL_RS09680
uniprot id: B0TRL7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

458817:SHAL RS17390
gene id: 458817:SHAL_RS17390
uniprot id: B0TRZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS19070
gene id: 458817:SHAL_RS19070
uniprot id: B0TUW1
names: Similarity
messages: Belongs to the peptidase S1C family.

458817:SHAL RS01185
gene id: 458817:SHAL_RS01185
uniprot id: B0TNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

458817:SHAL RS17310
gene id: 458817:SHAL_RS17310
uniprot id: B0TRX4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

458817:SHAL RS01370
gene id: 458817:SHAL_RS01370
uniprot id: B0TNU4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell inner membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

458817:SHAL RS22050
gene id: 458817:SHAL_RS22050
uniprot id: B0TPK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

458817:SHAL RS20100
gene id: 458817:SHAL_RS20100
uniprot id: B0TJ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS03010
gene id: 458817:SHAL_RS03010
uniprot id: B0TS30
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

458817:SHAL RS00710
gene id: 458817:SHAL_RS00710
uniprot id: B0TN04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

458817:SHAL RS05070
gene id: 458817:SHAL_RS05070
uniprot id: B0TVD1
names: Similarity
messages: Belongs to the glutamine synthetase family.

458817:SHAL RS00300
gene id: 458817:SHAL_RS00300
uniprot id: B0TM42
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

458817:SHAL RS02005
gene id: 458817:SHAL_RS02005
uniprot id: B0TQH9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

458817:SHAL RS09540
gene id: 458817:SHAL_RS09540
uniprot id: B0TRI9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

458817:SHAL RS15420
gene id: 458817:SHAL_RS15420
uniprot id: B0TP85
names: Activity Regulation
names: Caution
names: Domain
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

458817:SHAL RS05180
gene id: 458817:SHAL_RS05180
uniprot id: B0TIP5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

458817:SHAL RS06045
gene id: 458817:SHAL_RS06045
uniprot id: B0TJW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

458817:SHAL RS09215
gene id: 458817:SHAL_RS09215
uniprot id: B0TQU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

458817:SHAL RS01040
gene id: 458817:SHAL_RS01040
uniprot id: B0TN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

458817:SHAL RS15710
gene id: 458817:SHAL_RS15710
uniprot id: B0TPE0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS21130
gene id: 458817:SHAL_RS21130
uniprot id: B0TL86
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS00225
gene id: 458817:SHAL_RS00225
uniprot id: B0TLE4
names: Similarity
messages: Belongs to the peptidase S41A family.

458817:SHAL RS06070
gene id: 458817:SHAL_RS06070
uniprot id: B0TJX3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

458817:SHAL RS03495
gene id: 458817:SHAL_RS03495
uniprot id: B0TST2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

458817:SHAL RS11810
gene id: 458817:SHAL_RS11810
uniprot id: B0TVD8
names: Similarity
messages: Belongs to the peptidase A31 family.

458817:SHAL RS02200
gene id: 458817:SHAL_RS02200
uniprot id: B0TQL8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

458817:SHAL RS09645
gene id: 458817:SHAL_RS09645
uniprot id: B0TRL0
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

458817:SHAL RS15000
gene id: 458817:SHAL_RS15000
uniprot id: B0TMT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

458817:SHAL RS21470
gene id: 458817:SHAL_RS21470
uniprot id: B0TM28
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

458817:SHAL RS04535
gene id: 458817:SHAL_RS04535
uniprot id: B0TUG3
names: Similarity
messages: Belongs to the P(II) protein family.

458817:SHAL RS08920
gene id: 458817:SHAL_RS08920
uniprot id: B0TQ05
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

458817:SHAL RS00165
gene id: 458817:SHAL_RS00165
uniprot id: B0TLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

458817:SHAL RS21080
gene id: 458817:SHAL_RS21080
uniprot id: B0TL76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

458817:SHAL RS05795
gene id: 458817:SHAL_RS05795
uniprot id: B0TJC0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS11830
gene id: 458817:SHAL_RS11830
uniprot id: B0TVE2
names: Similarity
messages: Belongs to the HupF/HypC family.

458817:SHAL RS13185
gene id: 458817:SHAL_RS13185
uniprot id: B0TK73
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

458817:SHAL RS07175
gene id: 458817:SHAL_RS07175
uniprot id: B0TLL0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

458817:SHAL RS16700
gene id: 458817:SHAL_RS16700
uniprot id: B0TR45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

458817:SHAL RS07050
gene id: 458817:SHAL_RS07050
uniprot id: B0TLI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

458817:SHAL RS09925
gene id: 458817:SHAL_RS09925
uniprot id: B0TSA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

458817:SHAL RS00010
gene id: 458817:SHAL_RS00010
uniprot id: B0TLA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

458817:SHAL RS20500
gene id: 458817:SHAL_RS20500
uniprot id: B0TJT9
names: Subcellular Location Annotation
messages: Periplasm

458817:SHAL RS04215
gene id: 458817:SHAL_RS04215
uniprot id: B0TU99
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

458817:SHAL RS02435
gene id: 458817:SHAL_RS02435
uniprot id: B0TQR0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

458817:SHAL RS13055
gene id: 458817:SHAL_RS13055
uniprot id: B0TK49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

458817:SHAL RS01100
gene id: 458817:SHAL_RS01100
uniprot id: B0TNP1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

458817:SHAL RS15980
gene id: 458817:SHAL_RS15980
uniprot id: B0TQ50
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS11740
gene id: 458817:SHAL_RS11740
uniprot id: B0TUT1
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

458817:SHAL RS13760
gene id: 458817:SHAL_RS13760
uniprot id: B0TL02
names: Similarity
messages: Belongs to the Nudix hydrolase family.

458817:SHAL RS12945
gene id: 458817:SHAL_RS12945
uniprot id: B0TJP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

458817:SHAL RS19065
gene id: 458817:SHAL_RS19065
uniprot id: B0TUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

458817:SHAL RS11205
gene id: 458817:SHAL_RS11205
uniprot id: B0TTY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS18265
gene id: 458817:SHAL_RS18265
uniprot id: B0TTD3
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS12315
gene id: 458817:SHAL_RS12315
uniprot id: B0TIY2
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS07040
gene id: 458817:SHAL_RS07040
uniprot id: B0TLI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS11130
gene id: 458817:SHAL_RS11130
uniprot id: B0TTX2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS08660
gene id: 458817:SHAL_RS08660
uniprot id: B0TPW0
names: Similarity
messages: Belongs to the asparagine synthetase family.

458817:SHAL RS02485
gene id: 458817:SHAL_RS02485
uniprot id: B0TR91
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

458817:SHAL RS15780
gene id: 458817:SHAL_RS15780
uniprot id: B0TPF4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

458817:SHAL RS21835
gene id: 458817:SHAL_RS21835
uniprot id: B0TNM6
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS16400
gene id: 458817:SHAL_RS16400
uniprot id: B0TQZ5
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

458817:SHAL RS02375
gene id: 458817:SHAL_RS02375
uniprot id: B0TQP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

458817:SHAL RS21530
gene id: 458817:SHAL_RS21530
uniprot id: B0TMV8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS00795
gene id: 458817:SHAL_RS00795
uniprot id: B0TN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS19595
gene id: 458817:SHAL_RS19595
uniprot id: B0TVM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

458817:SHAL RS21415
gene id: 458817:SHAL_RS21415
uniprot id: B0TM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

458817:SHAL RS14685
gene id: 458817:SHAL_RS14685
uniprot id: B0TMM7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

458817:SHAL RS20375
gene id: 458817:SHAL_RS20375
uniprot id: B0TJR4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS12900
gene id: 458817:SHAL_RS12900
uniprot id: B0TJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

458817:SHAL RS21575
gene id: 458817:SHAL_RS21575
uniprot id: B0TMW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

458817:SHAL RS12815
gene id: 458817:SHAL_RS12815
uniprot id: B0TJM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS11765
gene id: 458817:SHAL_RS11765
uniprot id: B0TUT6
names: Similarity
messages: Belongs to the peptidase S9C family.

458817:SHAL RS21300
gene id: 458817:SHAL_RS21300
uniprot id: B0TLZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

458817:SHAL RS05650
gene id: 458817:SHAL_RS05650
uniprot id: B0TJ91
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

458817:SHAL RS11045
gene id: 458817:SHAL_RS11045
uniprot id: B0TTV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS03995
gene id: 458817:SHAL_RS03995
uniprot id: B0TTL2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS08200
gene id: 458817:SHAL_RS08200
uniprot id: B0TNY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

458817:SHAL RS20485
gene id: 458817:SHAL_RS20485
uniprot id: B0TJT6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS09975
gene id: 458817:SHAL_RS09975
uniprot id: B0TSB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

458817:SHAL RS18035
gene id: 458817:SHAL_RS18035
uniprot id: B0TT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS04390
gene id: 458817:SHAL_RS04390
uniprot id: B0TUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

458817:SHAL RS01375
gene id: 458817:SHAL_RS01375
uniprot id: B0TNU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS06080
gene id: 458817:SHAL_RS06080
uniprot id: B0TJX6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS19970
gene id: 458817:SHAL_RS19970
uniprot id: B0TJ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

458817:SHAL RS07130
gene id: 458817:SHAL_RS07130
uniprot id: B0TLK2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

458817:SHAL RS17990
gene id: 458817:SHAL_RS17990
uniprot id: B0TT81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

458817:SHAL RS21840
gene id: 458817:SHAL_RS21840
uniprot id: B0TNM7
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

458817:SHAL RS21325
gene id: 458817:SHAL_RS21325
uniprot id: B0TM02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

458817:SHAL RS11280
gene id: 458817:SHAL_RS11280
uniprot id: B0TUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

458817:SHAL RS08465
gene id: 458817:SHAL_RS08465
uniprot id: B0TP42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

458817:SHAL RS11050
gene id: 458817:SHAL_RS11050
uniprot id: B0TTV6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS10940
gene id: 458817:SHAL_RS10940
uniprot id: B0TTT5
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS12950
gene id: 458817:SHAL_RS12950
uniprot id: B0TJQ0
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

458817:SHAL RS08010
gene id: 458817:SHAL_RS08010
uniprot id: B0TNC0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08045
gene id: 458817:SHAL_RS08045
uniprot id: B0TNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).

458817:SHAL RS02765
gene id: 458817:SHAL_RS02765
uniprot id: B0TRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

458817:SHAL RS00100
gene id: 458817:SHAL_RS00100
uniprot id: B0TLC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

458817:SHAL RS03240
gene id: 458817:SHAL_RS03240
uniprot id: B0TS72
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS00940
gene id: 458817:SHAL_RS00940
uniprot id: B0TN49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS09170
gene id: 458817:SHAL_RS09170
uniprot id: B0TQT8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

458817:SHAL RS01215
gene id: 458817:SHAL_RS01215
uniprot id: B0TNR4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

458817:SHAL RS22235
gene id: 458817:SHAL_RS22235
uniprot id: B0TQF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

458817:SHAL RS19370
gene id: 458817:SHAL_RS19370
uniprot id: B0TV21
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS21210
gene id: 458817:SHAL_RS21210
uniprot id: B0TL96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS21270
gene id: 458817:SHAL_RS21270
uniprot id: B0TLZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

458817:SHAL RS12345
gene id: 458817:SHAL_RS12345
uniprot id: B0TIY8
names: Similarity
messages: Belongs to the peptidase S41A family.

458817:SHAL RS02130
gene id: 458817:SHAL_RS02130
uniprot id: B0TQK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

458817:SHAL RS13090
gene id: 458817:SHAL_RS13090
uniprot id: B0TK55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

458817:SHAL RS09465
gene id: 458817:SHAL_RS09465
uniprot id: B0TRH4
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

458817:SHAL RS01680
gene id: 458817:SHAL_RS01680
uniprot id: B0TPN7
names: Subcellular Location Annotation
messages: Periplasm

458817:SHAL RS17940
gene id: 458817:SHAL_RS17940
uniprot id: B0TT70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

458817:SHAL RS11650
gene id: 458817:SHAL_RS11650
uniprot id: B0TUR3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

458817:SHAL RS03200
gene id: 458817:SHAL_RS03200
uniprot id: B0TS64
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

458817:SHAL RS11395
gene id: 458817:SHAL_RS11395
uniprot id: B0TUL3
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

458817:SHAL RS20460
gene id: 458817:SHAL_RS20460
uniprot id: B0TJT1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

458817:SHAL RS21355
gene id: 458817:SHAL_RS21355
uniprot id: B0TM08
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

458817:SHAL RS09040
gene id: 458817:SHAL_RS09040
uniprot id: B0TQR3
names: Similarity
messages: Belongs to the nitroreductase family.

458817:SHAL RS17905
gene id: 458817:SHAL_RS17905
uniprot id: B0TT63
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

458817:SHAL RS00495
gene id: 458817:SHAL_RS00495
uniprot id: B0TM80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

458817:SHAL RS11005
gene id: 458817:SHAL_RS11005
uniprot id: B0TTU7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

458817:SHAL RS12385
gene id: 458817:SHAL_RS12385
uniprot id: B0TIZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

458817:SHAL RS08900
gene id: 458817:SHAL_RS08900
uniprot id: B0TQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

458817:SHAL RS14465
gene id: 458817:SHAL_RS14465
uniprot id: B0TLX0
names: Similarity
messages: Belongs to the CdaR family.

458817:SHAL RS03855
gene id: 458817:SHAL_RS03855
uniprot id: B0TTI4
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

458817:SHAL RS02230
gene id: 458817:SHAL_RS02230
uniprot id: B0TQM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS18065
gene id: 458817:SHAL_RS18065
uniprot id: B0TT96
names: Function
names: Similarity
messages: Belongs to the peptidase S9C family.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

458817:SHAL RS02220
gene id: 458817:SHAL_RS02220
uniprot id: B0TQM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

458817:SHAL RS17785
gene id: 458817:SHAL_RS17785
uniprot id: B0TSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

458817:SHAL RS17790
gene id: 458817:SHAL_RS17790
uniprot id: B0TSM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

458817:SHAL RS00465
gene id: 458817:SHAL_RS00465
uniprot id: B0TM74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS07700
gene id: 458817:SHAL_RS07700
uniprot id: B0TMJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS05205
gene id: 458817:SHAL_RS05205
uniprot id: B0TIQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS19260
gene id: 458817:SHAL_RS19260
uniprot id: B0TUZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS05515
gene id: 458817:SHAL_RS05515
uniprot id: B0TIW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

458817:SHAL RS03360
gene id: 458817:SHAL_RS03360
uniprot id: B0TSQ7
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

458817:SHAL RS18695
gene id: 458817:SHAL_RS18695
uniprot id: B0TU48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

458817:SHAL RS05505
gene id: 458817:SHAL_RS05505
uniprot id: B0TIV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS05310
gene id: 458817:SHAL_RS05310
uniprot id: B0TIR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS09205
gene id: 458817:SHAL_RS09205
uniprot id: B0TQU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

458817:SHAL RS08365
gene id: 458817:SHAL_RS08365
uniprot id: B0TP22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

458817:SHAL RS03190
gene id: 458817:SHAL_RS03190
uniprot id: B0TS62
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

458817:SHAL RS14150
gene id: 458817:SHAL_RS14150
uniprot id: B0TLR0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

458817:SHAL RS11185
gene id: 458817:SHAL_RS11185
uniprot id: B0TTY3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

458817:SHAL RS08225
gene id: 458817:SHAL_RS08225
uniprot id: B0TNZ4
names: Similarity
messages: Belongs to the UPF0276 family.

458817:SHAL RS09510
gene id: 458817:SHAL_RS09510
uniprot id: B0TRI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

458817:SHAL RS05255
gene id: 458817:SHAL_RS05255
uniprot id: B0TIQ8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS13665
gene id: 458817:SHAL_RS13665
uniprot id: B0TKY2
names: Similarity
messages: Belongs to the peptidase S33 family.

458817:SHAL RS21365
gene id: 458817:SHAL_RS21365
uniprot id: B0TM10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

458817:SHAL RS12195
gene id: 458817:SHAL_RS12195
uniprot id: B0TIW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

458817:SHAL RS15085
gene id: 458817:SHAL_RS15085
uniprot id: B0TNF1
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

458817:SHAL RS15755
gene id: 458817:SHAL_RS15755
uniprot id: B0TPE9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS03845
gene id: 458817:SHAL_RS03845
uniprot id: B0TTI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

458817:SHAL RS10105
gene id: 458817:SHAL_RS10105
uniprot id: B0TSC4
names: Similarity
messages: Belongs to the UPF0381 family.

458817:SHAL RS07325
gene id: 458817:SHAL_RS07325
uniprot id: B0TMC0
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

458817:SHAL RS02070
gene id: 458817:SHAL_RS02070
uniprot id: B0TQJ2
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS02300
gene id: 458817:SHAL_RS02300
uniprot id: B0TQN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

458817:SHAL RS02500
gene id: 458817:SHAL_RS02500
uniprot id: B0TR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

458817:SHAL RS12350
gene id: 458817:SHAL_RS12350
uniprot id: B0TIY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.

458817:SHAL RS10460
gene id: 458817:SHAL_RS10460
uniprot id: B0TT11
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS03745
gene id: 458817:SHAL_RS03745
uniprot id: B0TSY1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS10660
gene id: 458817:SHAL_RS10660
uniprot id: B0TT41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS07865
gene id: 458817:SHAL_RS07865
uniprot id: B0TNB1
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

458817:SHAL RS04050
gene id: 458817:SHAL_RS04050
uniprot id: B0TTM3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

458817:SHAL RS10055
gene id: 458817:SHAL_RS10055
uniprot id: B0TSB9
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS15095
gene id: 458817:SHAL_RS15095
uniprot id: B0TNF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
messages: Periplasm

458817:SHAL RS21285
gene id: 458817:SHAL_RS21285
uniprot id: B0TLZ4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

458817:SHAL RS01440
gene id: 458817:SHAL_RS01440
uniprot id: B0TNV9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

458817:SHAL RS09200
gene id: 458817:SHAL_RS09200
uniprot id: B0TQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

458817:SHAL RS13400
gene id: 458817:SHAL_RS13400
uniprot id: B0TKB2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

458817:SHAL RS09505
gene id: 458817:SHAL_RS09505
uniprot id: B0TRI2
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

458817:SHAL RS05565
gene id: 458817:SHAL_RS05565
uniprot id: B0TJ74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

458817:SHAL RS00890
gene id: 458817:SHAL_RS00890
uniprot id: B0TN39
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS20120
gene id: 458817:SHAL_RS20120
uniprot id: B0TJ31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

458817:SHAL RS11825
gene id: 458817:SHAL_RS11825
uniprot id: B0TVE1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

458817:SHAL RS05745
gene id: 458817:SHAL_RS05745
uniprot id: B0TJB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

458817:SHAL RS06230
gene id: 458817:SHAL_RS06230
uniprot id: B0TK03
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

458817:SHAL RS04500
gene id: 458817:SHAL_RS04500
uniprot id: B0TUF6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

458817:SHAL RS14350
gene id: 458817:SHAL_RS14350
uniprot id: B0TLV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

458817:SHAL RS01155
gene id: 458817:SHAL_RS01155
uniprot id: B0TNQ2
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS02100
gene id: 458817:SHAL_RS02100
uniprot id: B0TQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

458817:SHAL RS04525
gene id: 458817:SHAL_RS04525
uniprot id: B0TUG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
messages: Periplasm

458817:SHAL RS10905
gene id: 458817:SHAL_RS10905
uniprot id: B0TTS8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS02390
gene id: 458817:SHAL_RS02390
uniprot id: B0TQQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS10730
gene id: 458817:SHAL_RS10730
uniprot id: B0TT55
names: Similarity
messages: Belongs to the peptidase S13 family.

458817:SHAL RS19920
gene id: 458817:SHAL_RS19920
uniprot id: B0TVU6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

458817:SHAL RS03755
gene id: 458817:SHAL_RS03755
uniprot id: B0TSY3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

458817:SHAL RS05700
gene id: 458817:SHAL_RS05700
uniprot id: B0TJA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS17450
gene id: 458817:SHAL_RS17450
uniprot id: B0TS02
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

458817:SHAL RS10695
gene id: 458817:SHAL_RS10695
uniprot id: B0TT48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

458817:SHAL RS08180
gene id: 458817:SHAL_RS08180
uniprot id: B0TNY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

458817:SHAL RS21970
gene id: 458817:SHAL_RS21970
uniprot id: B0TPI4
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

458817:SHAL RS04850
gene id: 458817:SHAL_RS04850
uniprot id: B0TV87
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

458817:SHAL RS11670
gene id: 458817:SHAL_RS11670
uniprot id: B0TUR7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

458817:SHAL RS21980
gene id: 458817:SHAL_RS21980
uniprot id: B0TPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

458817:SHAL RS03580
gene id: 458817:SHAL_RS03580
uniprot id: B0TSU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

458817:SHAL RS18690
gene id: 458817:SHAL_RS18690
uniprot id: B0TU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

458817:SHAL RS18030
gene id: 458817:SHAL_RS18030
uniprot id: B0TT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

458817:SHAL RS21405
gene id: 458817:SHAL_RS21405
uniprot id: B0TM18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

458817:SHAL RS22205
gene id: 458817:SHAL_RS22205
uniprot id: B0TQE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

458817:SHAL RS11055
gene id: 458817:SHAL_RS11055
uniprot id: B0TTV7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS11560
gene id: 458817:SHAL_RS11560
uniprot id: B0TUP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

458817:SHAL RS13815
gene id: 458817:SHAL_RS13815
uniprot id: B0TL13
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

458817:SHAL RS02015
gene id: 458817:SHAL_RS02015
uniprot id: B0TQI1
names: Similarity
messages: Belongs to the group II decarboxylase family.

458817:SHAL RS16685
gene id: 458817:SHAL_RS16685
uniprot id: B0TR42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS17255
gene id: 458817:SHAL_RS17255
uniprot id: B0TRW3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

458817:SHAL RS07455
gene id: 458817:SHAL_RS07455
uniprot id: B0TME5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

458817:SHAL RS09400
gene id: 458817:SHAL_RS09400
uniprot id: B0TQY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

458817:SHAL RS07375
gene id: 458817:SHAL_RS07375
uniprot id: B0TMD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

458817:SHAL RS09605
gene id: 458817:SHAL_RS09605
uniprot id: B0TRK2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

458817:SHAL RS05965
gene id: 458817:SHAL_RS05965
uniprot id: B0TJV2
names: Similarity
messages: Belongs to the YggT family.

458817:SHAL RS09855
gene id: 458817:SHAL_RS09855
uniprot id: B0TRP8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS05090
gene id: 458817:SHAL_RS05090
uniprot id: B0TIM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS07520
gene id: 458817:SHAL_RS07520
uniprot id: B0TMF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

458817:SHAL RS08340
gene id: 458817:SHAL_RS08340
uniprot id: B0TP17
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

458817:SHAL RS06220
gene id: 458817:SHAL_RS06220
uniprot id: B0TK01
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

458817:SHAL RS21390
gene id: 458817:SHAL_RS21390
uniprot id: B0TM15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

458817:SHAL RS03810
gene id: 458817:SHAL_RS03810
uniprot id: B0TTH5
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

458817:SHAL RS19705
gene id: 458817:SHAL_RS19705
uniprot id: B0TVQ3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

458817:SHAL RS05585
gene id: 458817:SHAL_RS05585
uniprot id: B0TJ78
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

458817:SHAL RS16115
gene id: 458817:SHAL_RS16115
uniprot id: B0TQ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS17745
gene id: 458817:SHAL_RS17745
uniprot id: B0TSL8
names: Similarity
messages: Belongs to the universal stress protein A family.

458817:SHAL RS15050
gene id: 458817:SHAL_RS15050
uniprot id: B0TMU8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

458817:SHAL RS16725
gene id: 458817:SHAL_RS16725
uniprot id: B0TR50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

458817:SHAL RS03050
gene id: 458817:SHAL_RS03050
uniprot id: B0TS35
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

458817:SHAL RS03780
gene id: 458817:SHAL_RS03780
uniprot id: B0TTG9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

458817:SHAL RS18320
gene id: 458817:SHAL_RS18320
uniprot id: B0TTE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

458817:SHAL RS00615
gene id: 458817:SHAL_RS00615
uniprot id: B0TMA4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

458817:SHAL RS19115
gene id: 458817:SHAL_RS19115
uniprot id: B0TUX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

458817:SHAL RS21360
gene id: 458817:SHAL_RS21360
uniprot id: B0TM09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

458817:SHAL RS21395
gene id: 458817:SHAL_RS21395
uniprot id: B0TM16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

458817:SHAL RS19625
gene id: 458817:SHAL_RS19625
uniprot id: B0TVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

458817:SHAL RS15705
gene id: 458817:SHAL_RS15705
uniprot id: B0TPD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

458817:SHAL RS04120
gene id: 458817:SHAL_RS04120
uniprot id: B0TTN7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

458817:SHAL RS03840
gene id: 458817:SHAL_RS03840
uniprot id: B0TTI1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

458817:SHAL RS14405
gene id: 458817:SHAL_RS14405
uniprot id: B0TLV8
names: Similarity
messages: Belongs to the FeoA family.

458817:SHAL RS12075
gene id: 458817:SHAL_RS12075
uniprot id: B0TVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
messages: Belongs to the KdsB family.
messages: Cytoplasm

458817:SHAL RS04310
gene id: 458817:SHAL_RS04310
uniprot id: B0TUB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

458817:SHAL RS19945
gene id: 458817:SHAL_RS19945
uniprot id: B0TVV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS08640
gene id: 458817:SHAL_RS08640
uniprot id: B0TPV6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS14400
gene id: 458817:SHAL_RS14400
uniprot id: B0TLV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

458817:SHAL RS18465
gene id: 458817:SHAL_RS18465
uniprot id: B0TU02
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

458817:SHAL RS12430
gene id: 458817:SHAL_RS12430
uniprot id: B0TJ05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

458817:SHAL RS13675
gene id: 458817:SHAL_RS13675
uniprot id: B0TKY4
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

458817:SHAL RS19870
gene id: 458817:SHAL_RS19870
uniprot id: B0TVT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

458817:SHAL RS21475
gene id: 458817:SHAL_RS21475
uniprot id: B0TM29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

458817:SHAL RS01045
gene id: 458817:SHAL_RS01045
uniprot id: B0TN71
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS06085
gene id: 458817:SHAL_RS06085
uniprot id: B0TJX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS12390
gene id: 458817:SHAL_RS12390
uniprot id: B0TIZ7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

458817:SHAL RS17025
gene id: 458817:SHAL_RS17025
uniprot id: B0TRS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS07020
gene id: 458817:SHAL_RS07020
uniprot id: B0TLI1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

458817:SHAL RS16665
gene id: 458817:SHAL_RS16665
uniprot id: B0TR38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS19265
gene id: 458817:SHAL_RS19265
uniprot id: B0TV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS07500
gene id: 458817:SHAL_RS07500
uniprot id: B0TMF4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

458817:SHAL RS05900
gene id: 458817:SHAL_RS05900
uniprot id: B0TJD5
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

458817:SHAL RS08525
gene id: 458817:SHAL_RS08525
uniprot id: B0TP54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS04320
gene id: 458817:SHAL_RS04320
uniprot id: B0TUC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.

458817:SHAL RS00880
gene id: 458817:SHAL_RS00880
uniprot id: B0TN37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

458817:SHAL RS16720
gene id: 458817:SHAL_RS16720
uniprot id: B0TR49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

458817:SHAL RS07010
gene id: 458817:SHAL_RS07010
uniprot id: B0TLH9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

458817:SHAL RS12100
gene id: 458817:SHAL_RS12100
uniprot id: B0TVJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

458817:SHAL RS04820
gene id: 458817:SHAL_RS04820
uniprot id: B0TV81
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS19130
gene id: 458817:SHAL_RS19130
uniprot id: B0TUX3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

458817:SHAL RS18410
gene id: 458817:SHAL_RS18410
uniprot id: B0TTG1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

458817:SHAL RS17620
gene id: 458817:SHAL_RS17620
uniprot id: B0TSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

458817:SHAL RS11550
gene id: 458817:SHAL_RS11550
uniprot id: B0TUP3
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

458817:SHAL RS11640
gene id: 458817:SHAL_RS11640
uniprot id: B0TUR1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

458817:SHAL RS18845
gene id: 458817:SHAL_RS18845
uniprot id: B0TU72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

458817:SHAL RS21085
gene id: 458817:SHAL_RS21085
uniprot id: B0TL77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS18145
gene id: 458817:SHAL_RS18145
uniprot id: B0TTB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS22240
gene id: 458817:SHAL_RS22240
uniprot id: B0TQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

458817:SHAL RS16435
gene id: 458817:SHAL_RS16435
uniprot id: B0TR02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS06600
gene id: 458817:SHAL_RS06600
uniprot id: B0TKQ2
names: Similarity
messages: Belongs to the YjdM family.

458817:SHAL RS21385
gene id: 458817:SHAL_RS21385
uniprot id: B0TM14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

458817:SHAL RS19635
gene id: 458817:SHAL_RS19635
uniprot id: B0TVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS16820
gene id: 458817:SHAL_RS16820
uniprot id: B0TR62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

458817:SHAL RS17280
gene id: 458817:SHAL_RS17280
uniprot id: B0TRW8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08630
gene id: 458817:SHAL_RS08630
uniprot id: B0TPV4
names: Similarity
messages: Belongs to the peptidase S51 family.

458817:SHAL RS08735
gene id: 458817:SHAL_RS08735
uniprot id: B0TPX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

458817:SHAL RS08540
gene id: 458817:SHAL_RS08540
uniprot id: B0TP57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS16335
gene id: 458817:SHAL_RS16335
uniprot id: B0TQC0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

458817:SHAL RS00685
gene id: 458817:SHAL_RS00685
uniprot id: B0TMZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

458817:SHAL RS16745
gene id: 458817:SHAL_RS16745
uniprot id: B0TR54
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

458817:SHAL RS20735
gene id: 458817:SHAL_RS20735
uniprot id: B0TKG9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS14335
gene id: 458817:SHAL_RS14335
uniprot id: B0TLU7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

458817:SHAL RS15675
gene id: 458817:SHAL_RS15675
uniprot id: B0TPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

458817:SHAL RS15045
gene id: 458817:SHAL_RS15045
uniprot id: B0TMU7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

458817:SHAL RS21430
gene id: 458817:SHAL_RS21430
uniprot id: B0TM23
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

458817:SHAL RS05950
gene id: 458817:SHAL_RS05950
uniprot id: B0TJU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

458817:SHAL RS00080
gene id: 458817:SHAL_RS00080
uniprot id: B0TLB9
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

458817:SHAL RS09415
gene id: 458817:SHAL_RS09415
uniprot id: B0TQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

458817:SHAL RS08085
gene id: 458817:SHAL_RS08085
uniprot id: B0TND6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

458817:SHAL RS08355
gene id: 458817:SHAL_RS08355
uniprot id: B0TP20
names: Similarity
messages: Belongs to the acylphosphatase family.

458817:SHAL RS09180
gene id: 458817:SHAL_RS09180
uniprot id: B0TQU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

458817:SHAL RS19420
gene id: 458817:SHAL_RS19420
uniprot id: B0TV29
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

458817:SHAL RS06935
gene id: 458817:SHAL_RS06935
uniprot id: B0TLG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

458817:SHAL RS18275
gene id: 458817:SHAL_RS18275
uniprot id: B0TTD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

458817:SHAL RS06485
gene id: 458817:SHAL_RS06485
uniprot id: B0TKM9
names: Similarity
messages: Belongs to the cytochrome c-552 family.

458817:SHAL RS08565
gene id: 458817:SHAL_RS08565
uniprot id: B0TP63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

458817:SHAL RS07775
gene id: 458817:SHAL_RS07775
uniprot id: B0TN93
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

458817:SHAL RS18025
gene id: 458817:SHAL_RS18025
uniprot id: B0TT88
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

458817:SHAL RS19955
gene id: 458817:SHAL_RS19955
uniprot id: B0TVV3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

458817:SHAL RS20165
gene id: 458817:SHAL_RS20165
uniprot id: B0TJ40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

458817:SHAL RS09950
gene id: 458817:SHAL_RS09950
uniprot id: B0TSA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

458817:SHAL RS04395
gene id: 458817:SHAL_RS04395
uniprot id: B0TUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

458817:SHAL RS15745
gene id: 458817:SHAL_RS15745
uniprot id: B0TPE7
names: Similarity
messages: Belongs to the UPF0178 family.

458817:SHAL RS08960
gene id: 458817:SHAL_RS08960
uniprot id: B0TQ13
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS02240
gene id: 458817:SHAL_RS02240
uniprot id: B0TQM6
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

458817:SHAL RS17345
gene id: 458817:SHAL_RS17345
uniprot id: B0TRY1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

458817:SHAL RS01835
gene id: 458817:SHAL_RS01835
uniprot id: B0TPR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS22395
gene id: 458817:SHAL_RS22395
uniprot id: B0TUQ8
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

458817:SHAL RS10595
gene id: 458817:SHAL_RS10595
uniprot id: B0TT28
names: Similarity
messages: Belongs to the asparaginase 1 family.

458817:SHAL RS15405
gene id: 458817:SHAL_RS15405
uniprot id: B0TP82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

458817:SHAL RS00915
gene id: 458817:SHAL_RS00915
uniprot id: B0TN44
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS17640
gene id: 458817:SHAL_RS17640
uniprot id: B0TSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

458817:SHAL RS09705
gene id: 458817:SHAL_RS09705
uniprot id: B0TRM2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

458817:SHAL RS13640
gene id: 458817:SHAL_RS13640
uniprot id: B0TKX7
names: Similarity
messages: Belongs to the YciI family.

458817:SHAL RS12790
gene id: 458817:SHAL_RS12790
uniprot id: B0TJL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

458817:SHAL RS01000
gene id: 458817:SHAL_RS01000
uniprot id: B0TN62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS15590
gene id: 458817:SHAL_RS15590
uniprot id: B0TPB7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

458817:SHAL RS14370
gene id: 458817:SHAL_RS14370
uniprot id: B0TLV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

458817:SHAL RS07530
gene id: 458817:SHAL_RS07530
uniprot id: B0TMG0
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

458817:SHAL RS15915
gene id: 458817:SHAL_RS15915
uniprot id: B0TQ36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

458817:SHAL RS14340
gene id: 458817:SHAL_RS14340
uniprot id: B0TLU8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

458817:SHAL RS12885
gene id: 458817:SHAL_RS12885
uniprot id: B0TJN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

458817:SHAL RS21895
gene id: 458817:SHAL_RS21895
uniprot id: B0TNN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

458817:SHAL RS19790
gene id: 458817:SHAL_RS19790
uniprot id: B0TVS0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

458817:SHAL RS20155
gene id: 458817:SHAL_RS20155
uniprot id: B0TJ38
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

458817:SHAL RS16095
gene id: 458817:SHAL_RS16095
uniprot id: B0TQ74
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

458817:SHAL RS21555
gene id: 458817:SHAL_RS21555
uniprot id: B0TMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

458817:SHAL RS06295
gene id: 458817:SHAL_RS06295
uniprot id: B0TK16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

458817:SHAL RS20850
gene id: 458817:SHAL_RS20850
uniprot id: B0TKJ2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

458817:SHAL RS07645
gene id: 458817:SHAL_RS07645
uniprot id: B0TMI4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

458817:SHAL RS01230
gene id: 458817:SHAL_RS01230
uniprot id: B0TNR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

458817:SHAL RS11000
gene id: 458817:SHAL_RS11000
uniprot id: B0TTU6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

458817:SHAL RS13410
gene id: 458817:SHAL_RS13410
uniprot id: B0TKB4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

458817:SHAL RS05605
gene id: 458817:SHAL_RS05605
uniprot id: B0TJ82
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS05305
gene id: 458817:SHAL_RS05305
uniprot id: B0TIR8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08170
gene id: 458817:SHAL_RS08170
uniprot id: B0TNY2
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

458817:SHAL RS15525
gene id: 458817:SHAL_RS15525
uniprot id: B0TPA4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS01565
gene id: 458817:SHAL_RS01565
uniprot id: B0TPL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS08740
gene id: 458817:SHAL_RS08740
uniprot id: B0TPX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

458817:SHAL RS08950
gene id: 458817:SHAL_RS08950
uniprot id: B0TQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

458817:SHAL RS21240
gene id: 458817:SHAL_RS21240
uniprot id: B0TLA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

458817:SHAL RS00975
gene id: 458817:SHAL_RS00975
uniprot id: B0TN57
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

458817:SHAL RS11745
gene id: 458817:SHAL_RS11745
uniprot id: B0TUT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

458817:SHAL RS02190
gene id: 458817:SHAL_RS02190
uniprot id: B0TQL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

458817:SHAL RS06200
gene id: 458817:SHAL_RS06200
uniprot id: B0TJZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS03405
gene id: 458817:SHAL_RS03405
uniprot id: B0TSR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

458817:SHAL RS10410
gene id: 458817:SHAL_RS10410
uniprot id: B0TT01
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

458817:SHAL RS19820
gene id: 458817:SHAL_RS19820
uniprot id: B0TVS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

458817:SHAL RS01455
gene id: 458817:SHAL_RS01455
uniprot id: B0TNW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

458817:SHAL RS09870
gene id: 458817:SHAL_RS09870
uniprot id: B0TS89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

458817:SHAL RS06360
gene id: 458817:SHAL_RS06360
uniprot id: B0TK19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

458817:SHAL RS14190
gene id: 458817:SHAL_RS14190
uniprot id: B0TLR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

458817:SHAL RS08840
gene id: 458817:SHAL_RS08840
uniprot id: B0TPY9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

458817:SHAL RS02720
gene id: 458817:SHAL_RS02720
uniprot id: B0TRD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

458817:SHAL RS20110
gene id: 458817:SHAL_RS20110
uniprot id: B0TJ29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

458817:SHAL RS20495
gene id: 458817:SHAL_RS20495
uniprot id: B0TJT8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

458817:SHAL RS11135
gene id: 458817:SHAL_RS11135
uniprot id: B0TTX3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

458817:SHAL RS22265
gene id: 458817:SHAL_RS22265
uniprot id: B0TQG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

458817:SHAL RS19660
gene id: 458817:SHAL_RS19660
uniprot id: B0TVP3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

458817:SHAL RS16410
gene id: 458817:SHAL_RS16410
uniprot id: B0TQZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

458817:SHAL RS08020
gene id: 458817:SHAL_RS08020
uniprot id: B0TNC2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

458817:SHAL RS15265
gene id: 458817:SHAL_RS15265
uniprot id: B0TNI7
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS10875
gene id: 458817:SHAL_RS10875
uniprot id: B0TTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

458817:SHAL RS16190
gene id: 458817:SHAL_RS16190
uniprot id: B0TQ93
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS04370
gene id: 458817:SHAL_RS04370
uniprot id: B0TUD0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS09650
gene id: 458817:SHAL_RS09650
uniprot id: B0TRL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

458817:SHAL RS12095
gene id: 458817:SHAL_RS12095
uniprot id: B0TVJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

458817:SHAL RS10970
gene id: 458817:SHAL_RS10970
uniprot id: B0TTU0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS03185
gene id: 458817:SHAL_RS03185
uniprot id: B0TS61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS05470
gene id: 458817:SHAL_RS05470
uniprot id: B0TIV1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

458817:SHAL RS02550
gene id: 458817:SHAL_RS02550
uniprot id: B0TRA4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

458817:SHAL RS21465
gene id: 458817:SHAL_RS21465
uniprot id: B0TM27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

458817:SHAL RS07400
gene id: 458817:SHAL_RS07400
uniprot id: B0TMD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

458817:SHAL RS02210
gene id: 458817:SHAL_RS02210
uniprot id: B0TQM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

458817:SHAL RS07115
gene id: 458817:SHAL_RS07115
uniprot id: B0TLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

458817:SHAL RS01620
gene id: 458817:SHAL_RS01620
uniprot id: B0TPM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS05375
gene id: 458817:SHAL_RS05375
uniprot id: B0TIT2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

458817:SHAL RS18105
gene id: 458817:SHAL_RS18105
uniprot id: B0TTA2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

458817:SHAL RS03465
gene id: 458817:SHAL_RS03465
uniprot id: B0TSS7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS05455
gene id: 458817:SHAL_RS05455
uniprot id: B0TIU8
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

458817:SHAL RS21620
gene id: 458817:SHAL_RS21620
uniprot id: B0TMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS00145
gene id: 458817:SHAL_RS00145
uniprot id: B0TLD2
names: Similarity
messages: Belongs to the DprA/Smf family.

458817:SHAL RS06785
gene id: 458817:SHAL_RS06785
uniprot id: B0TKT5
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

458817:SHAL RS10170
gene id: 458817:SHAL_RS10170
uniprot id: B0TSD7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

458817:SHAL RS15375
gene id: 458817:SHAL_RS15375
uniprot id: B0TP76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

458817:SHAL RS20550
gene id: 458817:SHAL_RS20550
uniprot id: B0TKD1
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS10190
gene id: 458817:SHAL_RS10190
uniprot id: B0TSE1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS09355
gene id: 458817:SHAL_RS09355
uniprot id: B0TQX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

458817:SHAL RS02790
gene id: 458817:SHAL_RS02790
uniprot id: B0TRF2
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

458817:SHAL RS11865
gene id: 458817:SHAL_RS11865
uniprot id: B0TVE9
names: Similarity
messages: Belongs to the GSP E family.

458817:SHAL RS16315
gene id: 458817:SHAL_RS16315
uniprot id: B0TQB6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS08905
gene id: 458817:SHAL_RS08905
uniprot id: B0TQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

458817:SHAL RS04405
gene id: 458817:SHAL_RS04405
uniprot id: B0TUD7
names: Similarity
messages: Belongs to the RecJ family.

458817:SHAL RS20565
gene id: 458817:SHAL_RS20565
uniprot id: B0TKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

458817:SHAL RS20135
gene id: 458817:SHAL_RS20135
uniprot id: B0TJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS04655
gene id: 458817:SHAL_RS04655
uniprot id: B0TV50
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

458817:SHAL RS19545
gene id: 458817:SHAL_RS19545
uniprot id: B0TVL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS08430
gene id: 458817:SHAL_RS08430
uniprot id: B0TP35
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

458817:SHAL RS22155
gene id: 458817:SHAL_RS22155
uniprot id: B0TQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS18550
gene id: 458817:SHAL_RS18550
uniprot id: B0TU19
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS19995
gene id: 458817:SHAL_RS19995
uniprot id: B0TJ11
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

458817:SHAL RS00345
gene id: 458817:SHAL_RS00345
uniprot id: B0TM51
names: Similarity
messages: Belongs to the transglycosylase Slt family.

458817:SHAL RS03960
gene id: 458817:SHAL_RS03960
uniprot id: B0TTK5
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08730
gene id: 458817:SHAL_RS08730
uniprot id: B0TPX4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

458817:SHAL RS09445
gene id: 458817:SHAL_RS09445
uniprot id: B0TRH1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

458817:SHAL RS05030
gene id: 458817:SHAL_RS05030
uniprot id: B0TVC3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

458817:SHAL RS13405
gene id: 458817:SHAL_RS13405
uniprot id: B0TKB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

458817:SHAL RS00085
gene id: 458817:SHAL_RS00085
uniprot id: B0TLC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

458817:SHAL RS19760
gene id: 458817:SHAL_RS19760
uniprot id: B0TVR4
names: Similarity
messages: Belongs to the intimin/invasin family.

458817:SHAL RS04160
gene id: 458817:SHAL_RS04160
uniprot id: B0TTP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.

458817:SHAL RS02755
gene id: 458817:SHAL_RS02755
uniprot id: B0TRE5
names: Similarity
messages: Belongs to the RutC family.

458817:SHAL RS04635
gene id: 458817:SHAL_RS04635
uniprot id: B0TUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

458817:SHAL RS16265
gene id: 458817:SHAL_RS16265
uniprot id: B0TQA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

458817:SHAL RS14110
gene id: 458817:SHAL_RS14110
uniprot id: B0TLQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

458817:SHAL RS21890
gene id: 458817:SHAL_RS21890
uniprot id: B0TNN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

458817:SHAL RS21610
gene id: 458817:SHAL_RS21610
uniprot id: B0TMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

458817:SHAL RS13650
gene id: 458817:SHAL_RS13650
uniprot id: B0TKX9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

458817:SHAL RS07810
gene id: 458817:SHAL_RS07810
uniprot id: B0TNA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

458817:SHAL RS06135
gene id: 458817:SHAL_RS06135
uniprot id: B0TJY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

458817:SHAL RS10775
gene id: 458817:SHAL_RS10775
uniprot id: B0TTQ8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS19960
gene id: 458817:SHAL_RS19960
uniprot id: B0TVV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

458817:SHAL RS03670
gene id: 458817:SHAL_RS03670
uniprot id: B0TSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

458817:SHAL RS01115
gene id: 458817:SHAL_RS01115
uniprot id: B0TNP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS01315
gene id: 458817:SHAL_RS01315
uniprot id: B0TNT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

458817:SHAL RS09695
gene id: 458817:SHAL_RS09695
uniprot id: B0TRM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS02795
gene id: 458817:SHAL_RS02795
uniprot id: B0TRF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS16545
gene id: 458817:SHAL_RS16545
uniprot id: B0TR24
names: Similarity
messages: Belongs to the UPF0162 family.

458817:SHAL RS05390
gene id: 458817:SHAL_RS05390
uniprot id: B0TIT5
names: Similarity
messages: Belongs to the glutamate synthase family.

458817:SHAL RS17565
gene id: 458817:SHAL_RS17565
uniprot id: B0TSI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

458817:SHAL RS10215
gene id: 458817:SHAL_RS10215
uniprot id: B0TSE6
names: Similarity
messages: Belongs to the citrate synthase family.

458817:SHAL RS10720
gene id: 458817:SHAL_RS10720
uniprot id: B0TT53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

458817:SHAL RS12460
gene id: 458817:SHAL_RS12460
uniprot id: B0TJF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

458817:SHAL RS01305
gene id: 458817:SHAL_RS01305
uniprot id: B0TNT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

458817:SHAL RS11540
gene id: 458817:SHAL_RS11540
uniprot id: B0TUP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

458817:SHAL RS00565
gene id: 458817:SHAL_RS00565
uniprot id: B0TM94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

458817:SHAL RS05880
gene id: 458817:SHAL_RS05880
uniprot id: B0TJD1
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

458817:SHAL RS15535
gene id: 458817:SHAL_RS15535
uniprot id: B0TPA6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

458817:SHAL RS03275
gene id: 458817:SHAL_RS03275
uniprot id: B0TS79
names: Similarity
messages: Belongs to the carbamate kinase family.

458817:SHAL RS13970
gene id: 458817:SHAL_RS13970
uniprot id: B0TL45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS19020
gene id: 458817:SHAL_RS19020
uniprot id: B0TUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

458817:SHAL RS18150
gene id: 458817:SHAL_RS18150
uniprot id: B0TTB1
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS22000
gene id: 458817:SHAL_RS22000
uniprot id: B0TPJ0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

458817:SHAL RS14640
gene id: 458817:SHAL_RS14640
uniprot id: B0TML8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

458817:SHAL RS10340
gene id: 458817:SHAL_RS10340
uniprot id: B0TSZ0
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS00635
gene id: 458817:SHAL_RS00635
uniprot id: B0TMA8
names: Similarity
messages: Belongs to the MoaD family.

458817:SHAL RS10160
gene id: 458817:SHAL_RS10160
uniprot id: B0TSD5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

458817:SHAL RS07600
gene id: 458817:SHAL_RS07600
uniprot id: B0TMH4
names: Similarity
messages: Belongs to the MlaA family.

458817:SHAL RS09955
gene id: 458817:SHAL_RS09955
uniprot id: B0TSA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

458817:SHAL RS09565
gene id: 458817:SHAL_RS09565
uniprot id: B0TRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

458817:SHAL RS20580
gene id: 458817:SHAL_RS20580
uniprot id: B0TKD7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

458817:SHAL RS03850
gene id: 458817:SHAL_RS03850
uniprot id: B0TTI3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

458817:SHAL RS16445
gene id: 458817:SHAL_RS16445
uniprot id: B0TR04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

458817:SHAL RS02735
gene id: 458817:SHAL_RS02735
uniprot id: B0TRE1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

458817:SHAL RS16930
gene id: 458817:SHAL_RS16930
uniprot id: B0TRQ2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

458817:SHAL RS13460
gene id: 458817:SHAL_RS13460
uniprot id: B0TKC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

458817:SHAL RS04940
gene id: 458817:SHAL_RS04940
uniprot id: B0TVA5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

458817:SHAL RS13030
gene id: 458817:SHAL_RS13030
uniprot id: B0TK44
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS21295
gene id: 458817:SHAL_RS21295
uniprot id: B0TLZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

458817:SHAL RS02760
gene id: 458817:SHAL_RS02760
uniprot id: B0TRE6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

458817:SHAL RS06160
gene id: 458817:SHAL_RS06160
uniprot id: B0TJZ1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

458817:SHAL RS03865
gene id: 458817:SHAL_RS03865
uniprot id: B0TTI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

458817:SHAL RS09325
gene id: 458817:SHAL_RS09325
uniprot id: B0TQX0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS15350
gene id: 458817:SHAL_RS15350
uniprot id: B0TP71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

458817:SHAL RS05710
gene id: 458817:SHAL_RS05710
uniprot id: B0TJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS21330
gene id: 458817:SHAL_RS21330
uniprot id: B0TM03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

458817:SHAL RS02690
gene id: 458817:SHAL_RS02690
uniprot id: B0TRD2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS17050
gene id: 458817:SHAL_RS17050
uniprot id: B0TRS5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

458817:SHAL RS15105
gene id: 458817:SHAL_RS15105
uniprot id: B0TNF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
messages: Periplasm

458817:SHAL RS12025
gene id: 458817:SHAL_RS12025
uniprot id: B0TVI0
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS05420
gene id: 458817:SHAL_RS05420
uniprot id: B0TIU1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

458817:SHAL RS16875
gene id: 458817:SHAL_RS16875
uniprot id: B0TR72
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

458817:SHAL RS17750
gene id: 458817:SHAL_RS17750
uniprot id: B0TSL9
names: Similarity
messages: Belongs to the universal stress protein A family.

458817:SHAL RS20015
gene id: 458817:SHAL_RS20015
uniprot id: B0TJ15
names: Similarity
messages: Belongs to the arginase family.

458817:SHAL RS13680
gene id: 458817:SHAL_RS13680
uniprot id: B0TKY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

458817:SHAL RS07100
gene id: 458817:SHAL_RS07100
uniprot id: B0TLJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

458817:SHAL RS22190
gene id: 458817:SHAL_RS22190
uniprot id: B0TQE5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS16125
gene id: 458817:SHAL_RS16125
uniprot id: B0TQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

458817:SHAL RS02725
gene id: 458817:SHAL_RS02725
uniprot id: B0TRD9
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

458817:SHAL RS14720
gene id: 458817:SHAL_RS14720
uniprot id: B0TMN4
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

458817:SHAL RS02165
gene id: 458817:SHAL_RS02165
uniprot id: B0TQL1
names: Similarity
messages: Belongs to the UPF0758 family.

458817:SHAL RS16655
gene id: 458817:SHAL_RS16655
uniprot id: B0TR36
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

458817:SHAL RS17295
gene id: 458817:SHAL_RS17295
uniprot id: B0TRX1
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS19735
gene id: 458817:SHAL_RS19735
uniprot id: B0TVQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS09340
gene id: 458817:SHAL_RS09340
uniprot id: B0TQX3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

458817:SHAL RS18280
gene id: 458817:SHAL_RS18280
uniprot id: B0TTD6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

458817:SHAL RS19095
gene id: 458817:SHAL_RS19095
uniprot id: B0TUW6
names: Similarity
messages: Belongs to the BolA/IbaG family.

458817:SHAL RS12935
gene id: 458817:SHAL_RS12935
uniprot id: B0TJP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

458817:SHAL RS03740
gene id: 458817:SHAL_RS03740
uniprot id: B0TSY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

458817:SHAL RS09030
gene id: 458817:SHAL_RS09030
uniprot id: B0TQR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS13215
gene id: 458817:SHAL_RS13215
uniprot id: B0TK79
names: Similarity
messages: Belongs to the UPF0319 family.

458817:SHAL RS10425
gene id: 458817:SHAL_RS10425
uniprot id: B0TT04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

458817:SHAL RS02050
gene id: 458817:SHAL_RS02050
uniprot id: B0TQI8
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

458817:SHAL RS01245
gene id: 458817:SHAL_RS01245
uniprot id: B0TNS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

458817:SHAL RS22070
gene id: 458817:SHAL_RS22070
uniprot id: B0TPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

458817:SHAL RS05735
gene id: 458817:SHAL_RS05735
uniprot id: B0TJA8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

458817:SHAL RS15865
gene id: 458817:SHAL_RS15865
uniprot id: B0TPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS02515
gene id: 458817:SHAL_RS02515
uniprot id: B0TR97
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

458817:SHAL RS05920
gene id: 458817:SHAL_RS05920
uniprot id: B0TJD9
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS09220
gene id: 458817:SHAL_RS09220
uniprot id: B0TQU8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

458817:SHAL RS02810
gene id: 458817:SHAL_RS02810
uniprot id: B0TRF6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

458817:SHAL RS21845
gene id: 458817:SHAL_RS21845
uniprot id: B0TNM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

458817:SHAL RS22045
gene id: 458817:SHAL_RS22045
uniprot id: B0TPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

458817:SHAL RS19940
gene id: 458817:SHAL_RS19940
uniprot id: B0TVV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

458817:SHAL RS03080
gene id: 458817:SHAL_RS03080
uniprot id: B0TS41
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

458817:SHAL RS06235
gene id: 458817:SHAL_RS06235
uniprot id: B0TK04
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

458817:SHAL RS10300
gene id: 458817:SHAL_RS10300
uniprot id: B0TSG3
names: Similarity
messages: Belongs to the peptidase S8 family.

458817:SHAL RS16345
gene id: 458817:SHAL_RS16345
uniprot id: B0TQC2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

458817:SHAL RS18720
gene id: 458817:SHAL_RS18720
uniprot id: B0TU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

458817:SHAL RS21245
gene id: 458817:SHAL_RS21245
uniprot id: B0TLA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

458817:SHAL RS18980
gene id: 458817:SHAL_RS18980
uniprot id: B0TUU3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

458817:SHAL RS01085
gene id: 458817:SHAL_RS01085
uniprot id: B0TN79
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS09235
gene id: 458817:SHAL_RS09235
uniprot id: B0TQV1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

458817:SHAL RS11290
gene id: 458817:SHAL_RS11290
uniprot id: B0TUJ4
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS10630
gene id: 458817:SHAL_RS10630
uniprot id: B0TT35
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

458817:SHAL RS20010
gene id: 458817:SHAL_RS20010
uniprot id: B0TJ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

458817:SHAL RS09280
gene id: 458817:SHAL_RS09280
uniprot id: B0TQW0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

458817:SHAL RS02430
gene id: 458817:SHAL_RS02430
uniprot id: B0TQQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

458817:SHAL RS08125
gene id: 458817:SHAL_RS08125
uniprot id: B0TNE4
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS21955
gene id: 458817:SHAL_RS21955
uniprot id: B0TPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

458817:SHAL RS20030
gene id: 458817:SHAL_RS20030
uniprot id: B0TJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

458817:SHAL RS20365
gene id: 458817:SHAL_RS20365
uniprot id: B0TJR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

458817:SHAL RS14300
gene id: 458817:SHAL_RS14300
uniprot id: B0TLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS05935
gene id: 458817:SHAL_RS05935
uniprot id: B0TJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS22625
gene id: 458817:SHAL_RS22625
uniprot id: B0TIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

458817:SHAL RS09435
gene id: 458817:SHAL_RS09435
uniprot id: B0TQZ2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

458817:SHAL RS03585
gene id: 458817:SHAL_RS03585
uniprot id: B0TSU9
names: Similarity
messages: Belongs to the alkaline phosphatase family.

458817:SHAL RS18260
gene id: 458817:SHAL_RS18260
uniprot id: B0TTD2
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

458817:SHAL RS21020
gene id: 458817:SHAL_RS21020
uniprot id: B0TL64
names: Similarity
messages: Belongs to the UPF0102 family.

458817:SHAL RS21855
gene id: 458817:SHAL_RS21855
uniprot id: B0TNN0
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

458817:SHAL RS06635
gene id: 458817:SHAL_RS06635
uniprot id: B0TKQ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS08300
gene id: 458817:SHAL_RS08300
uniprot id: B0TP10
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

458817:SHAL RS12450
gene id: 458817:SHAL_RS12450
uniprot id: B0TJE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS08505
gene id: 458817:SHAL_RS08505
uniprot id: B0TP50
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS11715
gene id: 458817:SHAL_RS11715
uniprot id: B0TUS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

458817:SHAL RS07330
gene id: 458817:SHAL_RS07330
uniprot id: B0TMC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

458817:SHAL RS17975
gene id: 458817:SHAL_RS17975
uniprot id: B0TT78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Gfa family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.

458817:SHAL RS11490
gene id: 458817:SHAL_RS11490
uniprot id: B0TUN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

458817:SHAL RS12960
gene id: 458817:SHAL_RS12960
uniprot id: B0TK29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS03370
gene id: 458817:SHAL_RS03370
uniprot id: B0TSQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

458817:SHAL RS20225
gene id: 458817:SHAL_RS20225
uniprot id: B0TJ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

458817:SHAL RS13500
gene id: 458817:SHAL_RS13500
uniprot id: B0TKV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

458817:SHAL RS19785
gene id: 458817:SHAL_RS19785
uniprot id: B0TVR9
names: Similarity
messages: Belongs to the peptidase U62 family.

458817:SHAL RS00280
gene id: 458817:SHAL_RS00280
uniprot id: B0TM35
names: Similarity
messages: Belongs to the peptidase C40 family.

458817:SHAL RS05435
gene id: 458817:SHAL_RS05435
uniprot id: B0TIU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS02250
gene id: 458817:SHAL_RS02250
uniprot id: B0TQM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

458817:SHAL RS09330
gene id: 458817:SHAL_RS09330
uniprot id: B0TQX1
names: Similarity
messages: Belongs to the UPF0502 family.

458817:SHAL RS07425
gene id: 458817:SHAL_RS07425
uniprot id: B0TME0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

458817:SHAL RS13470
gene id: 458817:SHAL_RS13470
uniprot id: B0TKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

458817:SHAL RS13895
gene id: 458817:SHAL_RS13895
uniprot id: B0TL31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS19655
gene id: 458817:SHAL_RS19655
uniprot id: B0TVP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

458817:SHAL RS02380
gene id: 458817:SHAL_RS02380
uniprot id: B0TQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

458817:SHAL RS04705
gene id: 458817:SHAL_RS04705
uniprot id: B0TV60
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

458817:SHAL RS14065
gene id: 458817:SHAL_RS14065
uniprot id: B0TLP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS08930
gene id: 458817:SHAL_RS08930
uniprot id: B0TQ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

458817:SHAL RS16235
gene id: 458817:SHAL_RS16235
uniprot id: B0TQA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

458817:SHAL RS08315
gene id: 458817:SHAL_RS08315
uniprot id: B0TP13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

458817:SHAL RS11685
gene id: 458817:SHAL_RS11685
uniprot id: B0TUS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

458817:SHAL RS18160
gene id: 458817:SHAL_RS18160
uniprot id: B0TTB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS14035
gene id: 458817:SHAL_RS14035
uniprot id: B0TLN7
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS09350
gene id: 458817:SHAL_RS09350
uniprot id: B0TQX5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

458817:SHAL RS11475
gene id: 458817:SHAL_RS11475
uniprot id: B0TUM8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

458817:SHAL RS15900
gene id: 458817:SHAL_RS15900
uniprot id: B0TQ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

458817:SHAL RS13265
gene id: 458817:SHAL_RS13265
uniprot id: B0TK86
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS11710
gene id: 458817:SHAL_RS11710
uniprot id: B0TUS5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

458817:SHAL RS06170
gene id: 458817:SHAL_RS06170
uniprot id: B0TJZ3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

458817:SHAL RS00305
gene id: 458817:SHAL_RS00305
uniprot id: B0TM43
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08185
gene id: 458817:SHAL_RS08185
uniprot id: B0TNY5
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

458817:SHAL RS08245
gene id: 458817:SHAL_RS08245
uniprot id: B0TNZ9
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

458817:SHAL RS15390
gene id: 458817:SHAL_RS15390
uniprot id: B0TP79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

458817:SHAL RS18605
gene id: 458817:SHAL_RS18605
uniprot id: B0TU30
names: Similarity
messages: Belongs to the UPF0270 family.

458817:SHAL RS12065
gene id: 458817:SHAL_RS12065
uniprot id: B0TVI8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

458817:SHAL RS05835
gene id: 458817:SHAL_RS05835
uniprot id: B0TJC8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

458817:SHAL RS05675
gene id: 458817:SHAL_RS05675
uniprot id: B0TJ96
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

458817:SHAL RS19245
gene id: 458817:SHAL_RS19245
uniprot id: B0TUZ6
names: Similarity
messages: Belongs to the UPF0251 family.

458817:SHAL RS21205
gene id: 458817:SHAL_RS21205
uniprot id: B0TL95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

458817:SHAL RS14895
gene id: 458817:SHAL_RS14895
uniprot id: B0TMR7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

458817:SHAL RS08145
gene id: 458817:SHAL_RS08145
uniprot id: B0TNE8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

458817:SHAL RS09150
gene id: 458817:SHAL_RS09150
uniprot id: B0TQT4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

458817:SHAL RS05975
gene id: 458817:SHAL_RS05975
uniprot id: B0TJV4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

458817:SHAL RS15800
gene id: 458817:SHAL_RS15800
uniprot id: B0TPF9
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

458817:SHAL RS05165
gene id: 458817:SHAL_RS05165
uniprot id: B0TIP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

458817:SHAL RS19010
gene id: 458817:SHAL_RS19010
uniprot id: B0TUU9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

458817:SHAL RS13915
gene id: 458817:SHAL_RS13915
uniprot id: B0TL34
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS07620
gene id: 458817:SHAL_RS07620
uniprot id: B0TMH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

458817:SHAL RS17140
gene id: 458817:SHAL_RS17140
uniprot id: B0TRU2
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

458817:SHAL RS16325
gene id: 458817:SHAL_RS16325
uniprot id: B0TQB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

458817:SHAL RS09800
gene id: 458817:SHAL_RS09800
uniprot id: B0TRN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS17945
gene id: 458817:SHAL_RS17945
uniprot id: B0TT71
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

458817:SHAL RS04955
gene id: 458817:SHAL_RS04955
uniprot id: B0TVA8
names: Similarity
messages: Belongs to the DEAD box helicase family.

458817:SHAL RS18370
gene id: 458817:SHAL_RS18370
uniprot id: B0TTF4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

458817:SHAL RS04070
gene id: 458817:SHAL_RS04070
uniprot id: B0TTM7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

458817:SHAL RS03925
gene id: 458817:SHAL_RS03925
uniprot id: B0TTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS13445
gene id: 458817:SHAL_RS13445
uniprot id: B0TKC1
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS17935
gene id: 458817:SHAL_RS17935
uniprot id: B0TT69
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

458817:SHAL RS15235
gene id: 458817:SHAL_RS15235
uniprot id: B0TNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

458817:SHAL RS13735
gene id: 458817:SHAL_RS13735
uniprot id: B0TKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS21700
gene id: 458817:SHAL_RS21700
uniprot id: B0TMZ2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

458817:SHAL RS19025
gene id: 458817:SHAL_RS19025
uniprot id: B0TUV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

458817:SHAL RS13810
gene id: 458817:SHAL_RS13810
uniprot id: B0TL12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

458817:SHAL RS11680
gene id: 458817:SHAL_RS11680
uniprot id: B0TUR9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

458817:SHAL RS10180
gene id: 458817:SHAL_RS10180
uniprot id: B0TSD9
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS05225
gene id: 458817:SHAL_RS05225
uniprot id: B0TIQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

458817:SHAL RS10450
gene id: 458817:SHAL_RS10450
uniprot id: B0TT09
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

458817:SHAL RS03690
gene id: 458817:SHAL_RS03690
uniprot id: B0TSX0
names: Subcellular Location Annotation
messages: Cell inner membrane

458817:SHAL RS05265
gene id: 458817:SHAL_RS05265
uniprot id: B0TIR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

458817:SHAL RS09225
gene id: 458817:SHAL_RS09225
uniprot id: B0TQU9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

458817:SHAL RS21010
gene id: 458817:SHAL_RS21010
uniprot id: B0TL62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

458817:SHAL RS12015
gene id: 458817:SHAL_RS12015
uniprot id: B0TVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

458817:SHAL RS18055
gene id: 458817:SHAL_RS18055
uniprot id: B0TT94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

458817:SHAL RS09380
gene id: 458817:SHAL_RS09380
uniprot id: B0TQY1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

458817:SHAL RS03635
gene id: 458817:SHAL_RS03635
uniprot id: B0TSV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS13730
gene id: 458817:SHAL_RS13730
uniprot id: B0TKZ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS04600
gene id: 458817:SHAL_RS04600
uniprot id: B0TUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

458817:SHAL RS11015
gene id: 458817:SHAL_RS11015
uniprot id: B0TTU9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

458817:SHAL RS00745
gene id: 458817:SHAL_RS00745
uniprot id: B0TN10
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

458817:SHAL RS05050
gene id: 458817:SHAL_RS05050
uniprot id: B0TVC7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

458817:SHAL RS05520
gene id: 458817:SHAL_RS05520
uniprot id: B0TIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

458817:SHAL RS22015
gene id: 458817:SHAL_RS22015
uniprot id: B0TPJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

458817:SHAL RS22010
gene id: 458817:SHAL_RS22010
uniprot id: B0TPJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

458817:SHAL RS17445
gene id: 458817:SHAL_RS17445
uniprot id: B0TS01
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

458817:SHAL RS11645
gene id: 458817:SHAL_RS11645
uniprot id: B0TUR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

458817:SHAL RS01920
gene id: 458817:SHAL_RS01920
uniprot id: B0TPT4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

458817:SHAL RS13450
gene id: 458817:SHAL_RS13450
uniprot id: B0TKC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS07145
gene id: 458817:SHAL_RS07145
uniprot id: B0TLK4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS18345
gene id: 458817:SHAL_RS18345
uniprot id: B0TTE9
names: Similarity
messages: Belongs to the MipA/OmpV family.

458817:SHAL RS08415
gene id: 458817:SHAL_RS08415
uniprot id: B0TP32
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS18780
gene id: 458817:SHAL_RS18780
uniprot id: B0TU64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

458817:SHAL RS03875
gene id: 458817:SHAL_RS03875
uniprot id: B0TTI8
names: Similarity
messages: Belongs to the peptidase M17 family.

458817:SHAL RS00400
gene id: 458817:SHAL_RS00400
uniprot id: B0TM61
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS13635
gene id: 458817:SHAL_RS13635
uniprot id: B0TKX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

458817:SHAL RS07870
gene id: 458817:SHAL_RS07870
uniprot id: B0TNB2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

458817:SHAL RS21515
gene id: 458817:SHAL_RS21515
uniprot id: B0TMV5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

458817:SHAL RS21440
gene id: 458817:SHAL_RS21440
uniprot id: B0TM25
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS01430
gene id: 458817:SHAL_RS01430
uniprot id: B0TNV7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

458817:SHAL RS02225
gene id: 458817:SHAL_RS02225
uniprot id: B0TQM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

458817:SHAL RS07390
gene id: 458817:SHAL_RS07390
uniprot id: B0TMD3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

458817:SHAL RS13705
gene id: 458817:SHAL_RS13705
uniprot id: B0TKZ1
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS01795
gene id: 458817:SHAL_RS01795
uniprot id: B0TPR0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS12175
gene id: 458817:SHAL_RS12175
uniprot id: B0TVL0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

458817:SHAL RS07415
gene id: 458817:SHAL_RS07415
uniprot id: B0TMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

458817:SHAL RS05335
gene id: 458817:SHAL_RS05335
uniprot id: B0TIS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS08155
gene id: 458817:SHAL_RS08155
uniprot id: B0TNX9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

458817:SHAL RS12090
gene id: 458817:SHAL_RS12090
uniprot id: B0TVJ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS18140
gene id: 458817:SHAL_RS18140
uniprot id: B0TTA9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS02530
gene id: 458817:SHAL_RS02530
uniprot id: B0TRA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

458817:SHAL RS01865
gene id: 458817:SHAL_RS01865
uniprot id: B0TPS3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

458817:SHAL RS19170
gene id: 458817:SHAL_RS19170
uniprot id: B0TUY1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

458817:SHAL RS20605
gene id: 458817:SHAL_RS20605
uniprot id: B0TKE2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

458817:SHAL RS04570
gene id: 458817:SHAL_RS04570
uniprot id: B0TUH1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

458817:SHAL RS03460
gene id: 458817:SHAL_RS03460
uniprot id: B0TSS6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS08335
gene id: 458817:SHAL_RS08335
uniprot id: B0TP16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS08175
gene id: 458817:SHAL_RS08175
uniprot id: B0TNY3
names: Similarity
messages: Belongs to the HesB/IscA family.

458817:SHAL RS08510
gene id: 458817:SHAL_RS08510
uniprot id: B0TP51
names: Similarity
messages: Belongs to the band 7/mec-2 family.

458817:SHAL RS02945
gene id: 458817:SHAL_RS02945
uniprot id: B0TS20
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS21600
gene id: 458817:SHAL_RS21600
uniprot id: B0TMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS12925
gene id: 458817:SHAL_RS12925
uniprot id: B0TJP5
names: Similarity
messages: Belongs to the glutamate synthase family.

458817:SHAL RS04640
gene id: 458817:SHAL_RS04640
uniprot id: B0TUI5
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

458817:SHAL RS06555
gene id: 458817:SHAL_RS06555
uniprot id: B0TKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Membrane

458817:SHAL RS12275
gene id: 458817:SHAL_RS12275
uniprot id: B0TIX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

458817:SHAL RS11210
gene id: 458817:SHAL_RS11210
uniprot id: B0TTY8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS16570
gene id: 458817:SHAL_RS16570
uniprot id: B0TR29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

458817:SHAL RS17900
gene id: 458817:SHAL_RS17900
uniprot id: B0TSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

458817:SHAL RS10860
gene id: 458817:SHAL_RS10860
uniprot id: B0TTS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

458817:SHAL RS08695
gene id: 458817:SHAL_RS08695
uniprot id: B0TPW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

458817:SHAL RS04615
gene id: 458817:SHAL_RS04615
uniprot id: B0TUI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

458817:SHAL RS12405
gene id: 458817:SHAL_RS12405
uniprot id: B0TJ00
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

458817:SHAL RS18295
gene id: 458817:SHAL_RS18295
uniprot id: B0TTD9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

458817:SHAL RS16185
gene id: 458817:SHAL_RS16185
uniprot id: B0TQ92
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

458817:SHAL RS07590
gene id: 458817:SHAL_RS07590
uniprot id: B0TMH2
names: Similarity
messages: Belongs to the type III secretion exporter family.

458817:SHAL RS16395
gene id: 458817:SHAL_RS16395
uniprot id: B0TQZ4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

458817:SHAL RS22320
gene id: 458817:SHAL_RS22320
uniprot id: B0TQH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

458817:SHAL RS01695
gene id: 458817:SHAL_RS01695
uniprot id: B0TPP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS02395
gene id: 458817:SHAL_RS02395
uniprot id: B0TQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

458817:SHAL RS10700
gene id: 458817:SHAL_RS10700
uniprot id: B0TT49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

458817:SHAL RS16575
gene id: 458817:SHAL_RS16575
uniprot id: B0TR30
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

458817:SHAL RS09195
gene id: 458817:SHAL_RS09195
uniprot id: B0TQU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

458817:SHAL RS19275
gene id: 458817:SHAL_RS19275
uniprot id: B0TV02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

458817:SHAL RS06110
gene id: 458817:SHAL_RS06110
uniprot id: B0TJY1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS00485
gene id: 458817:SHAL_RS00485
uniprot id: B0TM78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

458817:SHAL RS19720
gene id: 458817:SHAL_RS19720
uniprot id: B0TVQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS14305
gene id: 458817:SHAL_RS14305
uniprot id: B0TLU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS13700
gene id: 458817:SHAL_RS13700
uniprot id: B0TKZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS18665
gene id: 458817:SHAL_RS18665
uniprot id: B0TU42
names: Similarity
messages: Belongs to the peptidase S9C family.

458817:SHAL RS07110
gene id: 458817:SHAL_RS07110
uniprot id: B0TLJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS16075
gene id: 458817:SHAL_RS16075
uniprot id: B0TQ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

458817:SHAL RS01650
gene id: 458817:SHAL_RS01650
uniprot id: B0TPN1
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

458817:SHAL RS17630
gene id: 458817:SHAL_RS17630
uniprot id: B0TSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

458817:SHAL RS07080
gene id: 458817:SHAL_RS07080
uniprot id: B0TLJ3
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

458817:SHAL RS01025
gene id: 458817:SHAL_RS01025
uniprot id: B0TN67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

458817:SHAL RS01530
gene id: 458817:SHAL_RS01530
uniprot id: B0TNX7
names: Subcellular Location Annotation
messages: Periplasm

458817:SHAL RS19125
gene id: 458817:SHAL_RS19125
uniprot id: B0TUX2
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS03735
gene id: 458817:SHAL_RS03735
uniprot id: B0TSX9
names: Similarity
messages: Belongs to the catalase family.

458817:SHAL RS16490
gene id: 458817:SHAL_RS16490
uniprot id: B0TR13
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08165
gene id: 458817:SHAL_RS08165
uniprot id: B0TNY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

458817:SHAL RS00700
gene id: 458817:SHAL_RS00700
uniprot id: B0TN02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS17865
gene id: 458817:SHAL_RS17865
uniprot id: B0TSP1
names: Subcellular Location Annotation
messages: Periplasm

458817:SHAL RS18755
gene id: 458817:SHAL_RS18755
uniprot id: B0TU60
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

458817:SHAL RS08290
gene id: 458817:SHAL_RS08290
uniprot id: B0TP08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

458817:SHAL RS08305
gene id: 458817:SHAL_RS08305
uniprot id: B0TP11
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS22025
gene id: 458817:SHAL_RS22025
uniprot id: B0TPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

458817:SHAL RS20370
gene id: 458817:SHAL_RS20370
uniprot id: B0TJR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

458817:SHAL RS14115
gene id: 458817:SHAL_RS14115
uniprot id: B0TLQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

458817:SHAL RS20045
gene id: 458817:SHAL_RS20045
uniprot id: B0TJ21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

458817:SHAL RS12125
gene id: 458817:SHAL_RS12125
uniprot id: B0TVK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

458817:SHAL RS21965
gene id: 458817:SHAL_RS21965
uniprot id: B0TPI3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

458817:SHAL RS21425
gene id: 458817:SHAL_RS21425
uniprot id: B0TM22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

458817:SHAL RS08705
gene id: 458817:SHAL_RS08705
uniprot id: B0TPW9
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS01295
gene id: 458817:SHAL_RS01295
uniprot id: B0TNS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

458817:SHAL RS21805
gene id: 458817:SHAL_RS21805
uniprot id: B0TNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS05575
gene id: 458817:SHAL_RS05575
uniprot id: B0TJ76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

458817:SHAL RS08855
gene id: 458817:SHAL_RS08855
uniprot id: B0TPZ2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

458817:SHAL RS04315
gene id: 458817:SHAL_RS04315
uniprot id: B0TUB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

458817:SHAL RS09575
gene id: 458817:SHAL_RS09575
uniprot id: B0TRJ6
names: Similarity
messages: Belongs to the peptidase C59 family.

458817:SHAL RS01345
gene id: 458817:SHAL_RS01345
uniprot id: B0TNT9
names: Subunit
messages: Monomer.

458817:SHAL RS20000
gene id: 458817:SHAL_RS20000
uniprot id: B0TJ12
names: Similarity
messages: Belongs to the glutamine synthetase family.

458817:SHAL RS05690
gene id: 458817:SHAL_RS05690
uniprot id: B0TJ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

458817:SHAL RS08375
gene id: 458817:SHAL_RS08375
uniprot id: B0TP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

458817:SHAL RS01250
gene id: 458817:SHAL_RS01250
uniprot id: B0TNS1
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS04860
gene id: 458817:SHAL_RS04860
uniprot id: B0TV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

458817:SHAL RS05160
gene id: 458817:SHAL_RS05160
uniprot id: B0TIP1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

458817:SHAL RS19465
gene id: 458817:SHAL_RS19465
uniprot id: B0TV38
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

458817:SHAL RS03590
gene id: 458817:SHAL_RS03590
uniprot id: B0TSV0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

458817:SHAL RS12135
gene id: 458817:SHAL_RS12135
uniprot id: B0TVK2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

458817:SHAL RS11895
gene id: 458817:SHAL_RS11895
uniprot id: B0TVF5
names: Similarity
messages: Belongs to the bacterial secretin family.

458817:SHAL RS08710
gene id: 458817:SHAL_RS08710
uniprot id: B0TPX0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

458817:SHAL RS05655
gene id: 458817:SHAL_RS05655
uniprot id: B0TJ92
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

458817:SHAL RS08310
gene id: 458817:SHAL_RS08310
uniprot id: B0TP12
names: Similarity
messages: Belongs to the intimin/invasin family.

458817:SHAL RS16295
gene id: 458817:SHAL_RS16295
uniprot id: B0TQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

458817:SHAL RS11400
gene id: 458817:SHAL_RS11400
uniprot id: B0TUL4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

458817:SHAL RS08240
gene id: 458817:SHAL_RS08240
uniprot id: B0TNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS08150
gene id: 458817:SHAL_RS08150
uniprot id: B0TNE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS14395
gene id: 458817:SHAL_RS14395
uniprot id: B0TLV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

458817:SHAL RS06265
gene id: 458817:SHAL_RS06265
uniprot id: B0TK10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

458817:SHAL RS18420
gene id: 458817:SHAL_RS18420
uniprot id: B0TTG3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS02990
gene id: 458817:SHAL_RS02990
uniprot id: B0TS29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

458817:SHAL RS19630
gene id: 458817:SHAL_RS19630
uniprot id: B0TVN5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

458817:SHAL RS20865
gene id: 458817:SHAL_RS20865
uniprot id: B0TKJ5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

458817:SHAL RS11235
gene id: 458817:SHAL_RS11235
uniprot id: B0TTZ3
names: Similarity
messages: Belongs to the peptidase S16 family.

458817:SHAL RS10575
gene id: 458817:SHAL_RS10575
uniprot id: B0TT24
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

458817:SHAL RS17330
gene id: 458817:SHAL_RS17330
uniprot id: B0TRX8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS01130
gene id: 458817:SHAL_RS01130
uniprot id: B0TNP7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

458817:SHAL RS09390
gene id: 458817:SHAL_RS09390
uniprot id: B0TQY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

458817:SHAL RS09965
gene id: 458817:SHAL_RS09965
uniprot id: B0TSA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS18840
gene id: 458817:SHAL_RS18840
uniprot id: B0TU71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

458817:SHAL RS09685
gene id: 458817:SHAL_RS09685
uniprot id: B0TRL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

458817:SHAL RS03890
gene id: 458817:SHAL_RS03890
uniprot id: B0TTJ1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

458817:SHAL RS20115
gene id: 458817:SHAL_RS20115
uniprot id: B0TJ30
names: Similarity
messages: Belongs to the thioredoxin family.

458817:SHAL RS14925
gene id: 458817:SHAL_RS14925
uniprot id: B0TMS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

458817:SHAL RS08285
gene id: 458817:SHAL_RS08285
uniprot id: B0TP07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS06020
gene id: 458817:SHAL_RS06020
uniprot id: B0TJW3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS09960
gene id: 458817:SHAL_RS09960
uniprot id: B0TSA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

458817:SHAL RS19035
gene id: 458817:SHAL_RS19035
uniprot id: B0TUV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

458817:SHAL RS07205
gene id: 458817:SHAL_RS07205
uniprot id: B0TLL6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

458817:SHAL RS05085
gene id: 458817:SHAL_RS05085
uniprot id: B0TVD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS04960
gene id: 458817:SHAL_RS04960
uniprot id: B0TVA9
names: Similarity
messages: Belongs to the peptidase M24B family.

458817:SHAL RS20020
gene id: 458817:SHAL_RS20020
uniprot id: B0TJ16
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

458817:SHAL RS10725
gene id: 458817:SHAL_RS10725
uniprot id: B0TT54
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS02480
gene id: 458817:SHAL_RS02480
uniprot id: B0TR90
names: Similarity
messages: Belongs to the GARS family.

458817:SHAL RS00900
gene id: 458817:SHAL_RS00900
uniprot id: B0TN41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS16555
gene id: 458817:SHAL_RS16555
uniprot id: B0TR26
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

458817:SHAL RS21125
gene id: 458817:SHAL_RS21125
uniprot id: B0TL85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

458817:SHAL RS10145
gene id: 458817:SHAL_RS10145
uniprot id: B0TSD2
names: Similarity
messages: Belongs to the pyruvate kinase family.

458817:SHAL RS12520
gene id: 458817:SHAL_RS12520
uniprot id: B0TJG3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

458817:SHAL RS00585
gene id: 458817:SHAL_RS00585
uniprot id: B0TM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

458817:SHAL RS00060
gene id: 458817:SHAL_RS00060
uniprot id: B0TLB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

458817:SHAL RS12655
gene id: 458817:SHAL_RS12655
uniprot id: B0TJJ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

458817:SHAL RS13430
gene id: 458817:SHAL_RS13430
uniprot id: B0TKB8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

458817:SHAL RS04830
gene id: 458817:SHAL_RS04830
uniprot id: B0TV83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS04625
gene id: 458817:SHAL_RS04625
uniprot id: B0TUI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS11925
gene id: 458817:SHAL_RS11925
uniprot id: B0TVG1
names: Similarity
messages: Belongs to the YkuD family.

458817:SHAL RS17960
gene id: 458817:SHAL_RS17960
uniprot id: B0TT74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

458817:SHAL RS08895
gene id: 458817:SHAL_RS08895
uniprot id: B0TQ00
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

458817:SHAL RS14955
gene id: 458817:SHAL_RS14955
uniprot id: B0TMS9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS07385
gene id: 458817:SHAL_RS07385
uniprot id: B0TMD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

458817:SHAL RS01605
gene id: 458817:SHAL_RS01605
uniprot id: B0TPM4
names: Similarity
messages: Belongs to the peptidase M16 family.

458817:SHAL RS02295
gene id: 458817:SHAL_RS02295
uniprot id: B0TQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

458817:SHAL RS18215
gene id: 458817:SHAL_RS18215
uniprot id: B0TTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

458817:SHAL RS08500
gene id: 458817:SHAL_RS08500
uniprot id: B0TP49
names: Similarity
messages: Belongs to the universal stress protein A family.

458817:SHAL RS08190
gene id: 458817:SHAL_RS08190
uniprot id: B0TNY6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

458817:SHAL RS21335
gene id: 458817:SHAL_RS21335
uniprot id: B0TM04
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

458817:SHAL RS22150
gene id: 458817:SHAL_RS22150
uniprot id: B0TQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

458817:SHAL RS11820
gene id: 458817:SHAL_RS11820
uniprot id: B0TVE0
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

458817:SHAL RS16205
gene id: 458817:SHAL_RS16205
uniprot id: B0TQ96
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

458817:SHAL RS15360
gene id: 458817:SHAL_RS15360
uniprot id: B0TP73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

458817:SHAL RS12420
gene id: 458817:SHAL_RS12420
uniprot id: B0TJ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

458817:SHAL RS21750
gene id: 458817:SHAL_RS21750
uniprot id: B0TNK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

458817:SHAL RS01825
gene id: 458817:SHAL_RS01825
uniprot id: B0TPR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

458817:SHAL RS04155
gene id: 458817:SHAL_RS04155
uniprot id: B0TTP4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

458817:SHAL RS04000
gene id: 458817:SHAL_RS04000
uniprot id: B0TTL3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS04305
gene id: 458817:SHAL_RS04305
uniprot id: B0TUB7
names: Similarity
messages: Belongs to the TPP enzyme family.

458817:SHAL RS05150
gene id: 458817:SHAL_RS05150
uniprot id: B0TIN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

458817:SHAL RS13585
gene id: 458817:SHAL_RS13585
uniprot id: B0TKW6
names: Similarity
messages: Belongs to the peptidase S49 family.

458817:SHAL RS05370
gene id: 458817:SHAL_RS05370
uniprot id: B0TIT1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

458817:SHAL RS17415
gene id: 458817:SHAL_RS17415
uniprot id: B0TRZ5
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS07805
gene id: 458817:SHAL_RS07805
uniprot id: B0TN99
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

458817:SHAL RS21040
gene id: 458817:SHAL_RS21040
uniprot id: B0TL68
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS04560
gene id: 458817:SHAL_RS04560
uniprot id: B0TUG9
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS09930
gene id: 458817:SHAL_RS09930
uniprot id: B0TSA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

458817:SHAL RS14650
gene id: 458817:SHAL_RS14650
uniprot id: B0TMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS00725
gene id: 458817:SHAL_RS00725
uniprot id: B0TN06
names: Similarity
messages: Belongs to the intimin/invasin family.

458817:SHAL RS22230
gene id: 458817:SHAL_RS22230
uniprot id: B0TQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

458817:SHAL RS04415
gene id: 458817:SHAL_RS04415
uniprot id: B0TUD9
names: Similarity
messages: Belongs to the UPF0597 family.

458817:SHAL RS08250
gene id: 458817:SHAL_RS08250
uniprot id: B0TP00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

458817:SHAL RS04400
gene id: 458817:SHAL_RS04400
uniprot id: B0TUD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

458817:SHAL RS00960
gene id: 458817:SHAL_RS00960
uniprot id: B0TN54
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

458817:SHAL RS04915
gene id: 458817:SHAL_RS04915
uniprot id: B0TVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

458817:SHAL RS16225
gene id: 458817:SHAL_RS16225
uniprot id: B0TQA0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

458817:SHAL RS07825
gene id: 458817:SHAL_RS07825
uniprot id: B0TNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

458817:SHAL RS14020
gene id: 458817:SHAL_RS14020
uniprot id: B0TLN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

458817:SHAL RS18860
gene id: 458817:SHAL_RS18860
uniprot id: B0TU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

458817:SHAL RS17760
gene id: 458817:SHAL_RS17760
uniprot id: B0TSM1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

458817:SHAL RS20820
gene id: 458817:SHAL_RS20820
uniprot id: B0TKI6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

458817:SHAL RS03195
gene id: 458817:SHAL_RS03195
uniprot id: B0TS63
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

458817:SHAL RS10605
gene id: 458817:SHAL_RS10605
uniprot id: B0TT30
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

458817:SHAL RS01180
gene id: 458817:SHAL_RS01180
uniprot id: B0TNQ7
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS21260
gene id: 458817:SHAL_RS21260
uniprot id: B0TLY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

458817:SHAL RS14195
gene id: 458817:SHAL_RS14195
uniprot id: B0TLR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

458817:SHAL RS01300
gene id: 458817:SHAL_RS01300
uniprot id: B0TNT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

458817:SHAL RS18020
gene id: 458817:SHAL_RS18020
uniprot id: B0TT87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

458817:SHAL RS13315
gene id: 458817:SHAL_RS13315
uniprot id: B0TK96
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

458817:SHAL RS15210
gene id: 458817:SHAL_RS15210
uniprot id: B0TNH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

458817:SHAL RS08345
gene id: 458817:SHAL_RS08345
uniprot id: B0TP18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

458817:SHAL RS02170
gene id: 458817:SHAL_RS02170
uniprot id: B0TQL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

458817:SHAL RS05800
gene id: 458817:SHAL_RS05800
uniprot id: B0TJC1
names: Similarity
messages: Belongs to the P(II) protein family.

458817:SHAL RS18770
gene id: 458817:SHAL_RS18770
uniprot id: B0TU62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

458817:SHAL RS14520
gene id: 458817:SHAL_RS14520
uniprot id: B0TLY1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

458817:SHAL RS20785
gene id: 458817:SHAL_RS20785
uniprot id: B0TKH9
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08915
gene id: 458817:SHAL_RS08915
uniprot id: B0TQ04
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

458817:SHAL RS09945
gene id: 458817:SHAL_RS09945
uniprot id: B0TSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

458817:SHAL RS21865
gene id: 458817:SHAL_RS21865
uniprot id: B0TNN2
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

458817:SHAL RS01105
gene id: 458817:SHAL_RS01105
uniprot id: B0TNP2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

458817:SHAL RS14375
gene id: 458817:SHAL_RS14375
uniprot id: B0TLV2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS18360
gene id: 458817:SHAL_RS18360
uniprot id: B0TTF2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

458817:SHAL RS12490
gene id: 458817:SHAL_RS12490
uniprot id: B0TJF6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

458817:SHAL RS05990
gene id: 458817:SHAL_RS05990
uniprot id: B0TJV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

458817:SHAL RS22255
gene id: 458817:SHAL_RS22255
uniprot id: B0TQF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

458817:SHAL RS10175
gene id: 458817:SHAL_RS10175
uniprot id: B0TSD8
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

458817:SHAL RS16730
gene id: 458817:SHAL_RS16730
uniprot id: B0TR51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

458817:SHAL RS05155
gene id: 458817:SHAL_RS05155
uniprot id: B0TIP0
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

458817:SHAL RS17365
gene id: 458817:SHAL_RS17365
uniprot id: B0TRY5
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

458817:SHAL RS06210
gene id: 458817:SHAL_RS06210
uniprot id: B0TJZ9
names: Subcellular Location Annotation
messages: Cell inner membrane

458817:SHAL RS03530
gene id: 458817:SHAL_RS03530
uniprot id: B0TST9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

458817:SHAL RS04555
gene id: 458817:SHAL_RS04555
uniprot id: B0TUG7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

458817:SHAL RS11730
gene id: 458817:SHAL_RS11730
uniprot id: B0TUS9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

458817:SHAL RS12435
gene id: 458817:SHAL_RS12435
uniprot id: B0TJE5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

458817:SHAL RS04755
gene id: 458817:SHAL_RS04755
uniprot id: B0TV70
names: Similarity
messages: Belongs to the MipA/OmpV family.

458817:SHAL RS02175
gene id: 458817:SHAL_RS02175
uniprot id: B0TQL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

458817:SHAL RS07860
gene id: 458817:SHAL_RS07860
uniprot id: B0TNB0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

458817:SHAL RS22170
gene id: 458817:SHAL_RS22170
uniprot id: B0TQE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

458817:SHAL RS19805
gene id: 458817:SHAL_RS19805
uniprot id: B0TVS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

458817:SHAL RS11570
gene id: 458817:SHAL_RS11570
uniprot id: B0TUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

458817:SHAL RS04580
gene id: 458817:SHAL_RS04580
uniprot id: B0TUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS15330
gene id: 458817:SHAL_RS15330
uniprot id: B0TNK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

458817:SHAL RS05480
gene id: 458817:SHAL_RS05480
uniprot id: B0TIV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

458817:SHAL RS19090
gene id: 458817:SHAL_RS19090
uniprot id: B0TUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

458817:SHAL RS16240
gene id: 458817:SHAL_RS16240
uniprot id: B0TQA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

458817:SHAL RS01495
gene id: 458817:SHAL_RS01495
uniprot id: B0TNX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

458817:SHAL RS04885
gene id: 458817:SHAL_RS04885
uniprot id: B0TV94
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS15015
gene id: 458817:SHAL_RS15015
uniprot id: B0TMU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS04815
gene id: 458817:SHAL_RS04815
uniprot id: B0TV80
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS12910
gene id: 458817:SHAL_RS12910
uniprot id: B0TJP2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

458817:SHAL RS07505
gene id: 458817:SHAL_RS07505
uniprot id: B0TMF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

458817:SHAL RS16830
gene id: 458817:SHAL_RS16830
uniprot id: B0TR64
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

458817:SHAL RS18560
gene id: 458817:SHAL_RS18560
uniprot id: B0TU21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

458817:SHAL RS18520
gene id: 458817:SHAL_RS18520
uniprot id: B0TU13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

458817:SHAL RS18335
gene id: 458817:SHAL_RS18335
uniprot id: B0TTE7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

458817:SHAL RS20420
gene id: 458817:SHAL_RS20420
uniprot id: B0TJS3
names: Subcellular Location Annotation
messages: Periplasm

458817:SHAL RS07465
gene id: 458817:SHAL_RS07465
uniprot id: B0TME7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

458817:SHAL RS00390
gene id: 458817:SHAL_RS00390
uniprot id: B0TM59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS21715
gene id: 458817:SHAL_RS21715
uniprot id: B0TMZ5
names: Similarity
messages: Belongs to the catalase family.

458817:SHAL RS04920
gene id: 458817:SHAL_RS04920
uniprot id: B0TVA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

458817:SHAL RS12170
gene id: 458817:SHAL_RS12170
uniprot id: B0TVK9
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

458817:SHAL RS15220
gene id: 458817:SHAL_RS15220
uniprot id: B0TNH8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS12610
gene id: 458817:SHAL_RS12610
uniprot id: B0TJI4
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS22080
gene id: 458817:SHAL_RS22080
uniprot id: B0TPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

458817:SHAL RS04610
gene id: 458817:SHAL_RS04610
uniprot id: B0TUH9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

458817:SHAL RS12165
gene id: 458817:SHAL_RS12165
uniprot id: B0TVK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

458817:SHAL RS12240
gene id: 458817:SHAL_RS12240
uniprot id: B0TIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

458817:SHAL RS19140
gene id: 458817:SHAL_RS19140
uniprot id: B0TUX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

458817:SHAL RS03750
gene id: 458817:SHAL_RS03750
uniprot id: B0TSY2
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

458817:SHAL RS10930
gene id: 458817:SHAL_RS10930
uniprot id: B0TTT3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

458817:SHAL RS06130
gene id: 458817:SHAL_RS06130
uniprot id: B0TJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS00620
gene id: 458817:SHAL_RS00620
uniprot id: B0TMA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

458817:SHAL RS14990
gene id: 458817:SHAL_RS14990
uniprot id: B0TMT6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

458817:SHAL RS17840
gene id: 458817:SHAL_RS17840
uniprot id: B0TSN5
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS14005
gene id: 458817:SHAL_RS14005
uniprot id: B0TL52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

458817:SHAL RS22335
gene id: 458817:SHAL_RS22335
uniprot id: B0TQH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

458817:SHAL RS01265
gene id: 458817:SHAL_RS01265
uniprot id: B0TNS4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

458817:SHAL RS16040
gene id: 458817:SHAL_RS16040
uniprot id: B0TQ63
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

458817:SHAL RS08535
gene id: 458817:SHAL_RS08535
uniprot id: B0TP56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS08560
gene id: 458817:SHAL_RS08560
uniprot id: B0TP62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

458817:SHAL RS05440
gene id: 458817:SHAL_RS05440
uniprot id: B0TIU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

458817:SHAL RS22290
gene id: 458817:SHAL_RS22290
uniprot id: B0TQG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

458817:SHAL RS11725
gene id: 458817:SHAL_RS11725
uniprot id: B0TUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS02705
gene id: 458817:SHAL_RS02705
uniprot id: B0TRD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

458817:SHAL RS04035
gene id: 458817:SHAL_RS04035
uniprot id: B0TTM0
names: Similarity
messages: Belongs to the aspartokinase family.

458817:SHAL RS19385
gene id: 458817:SHAL_RS19385
uniprot id: B0TV23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

458817:SHAL RS20040
gene id: 458817:SHAL_RS20040
uniprot id: B0TJ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

458817:SHAL RS22200
gene id: 458817:SHAL_RS22200
uniprot id: B0TQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS21055
gene id: 458817:SHAL_RS21055
uniprot id: B0TL71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

458817:SHAL RS05290
gene id: 458817:SHAL_RS05290
uniprot id: B0TIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS13465
gene id: 458817:SHAL_RS13465
uniprot id: B0TKC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS21435
gene id: 458817:SHAL_RS21435
uniprot id: B0TM24
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

458817:SHAL RS08910
gene id: 458817:SHAL_RS08910
uniprot id: B0TQ03
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

458817:SHAL RS12030
gene id: 458817:SHAL_RS12030
uniprot id: B0TVI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

458817:SHAL RS01880
gene id: 458817:SHAL_RS01880
uniprot id: B0TPS6
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS15815
gene id: 458817:SHAL_RS15815
uniprot id: B0TPG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

458817:SHAL RS21120
gene id: 458817:SHAL_RS21120
uniprot id: B0TL84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

458817:SHAL RS03535
gene id: 458817:SHAL_RS03535
uniprot id: B0TSU0
names: Similarity
messages: Belongs to the amidinotransferase family.

458817:SHAL RS21280
gene id: 458817:SHAL_RS21280
uniprot id: B0TLZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

458817:SHAL RS02000
gene id: 458817:SHAL_RS02000
uniprot id: B0TQH8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

458817:SHAL RS13345
gene id: 458817:SHAL_RS13345
uniprot id: B0TKA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

458817:SHAL RS07850
gene id: 458817:SHAL_RS07850
uniprot id: B0TNA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

458817:SHAL RS06400
gene id: 458817:SHAL_RS06400
uniprot id: B0TK27
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

458817:SHAL RS12185
gene id: 458817:SHAL_RS12185
uniprot id: B0TIW2
names: Similarity
messages: Belongs to the UPF0229 family.

458817:SHAL RS19520
gene id: 458817:SHAL_RS19520
uniprot id: B0TVL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

458817:SHAL RS08060
gene id: 458817:SHAL_RS08060
uniprot id: B0TND0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

458817:SHAL RS05995
gene id: 458817:SHAL_RS05995
uniprot id: B0TJV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

458817:SHAL RS13540
gene id: 458817:SHAL_RS13540
uniprot id: B0TKV7
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS18610
gene id: 458817:SHAL_RS18610
uniprot id: B0TU31
names: Similarity
messages: Belongs to the phosphoribulokinase family.

458817:SHAL RS12550
gene id: 458817:SHAL_RS12550
uniprot id: B0TJH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS00125
gene id: 458817:SHAL_RS00125
uniprot id: B0TLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

458817:SHAL RS10555
gene id: 458817:SHAL_RS10555
uniprot id: B0TT20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS08820
gene id: 458817:SHAL_RS08820
uniprot id: B0TPY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

458817:SHAL RS20220
gene id: 458817:SHAL_RS20220
uniprot id: B0TJ52
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

458817:SHAL RS19610
gene id: 458817:SHAL_RS19610
uniprot id: B0TVN1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

458817:SHAL RS20180
gene id: 458817:SHAL_RS20180
uniprot id: B0TJ43
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

458817:SHAL RS21995
gene id: 458817:SHAL_RS21995
uniprot id: B0TPI9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

458817:SHAL RS11520
gene id: 458817:SHAL_RS11520
uniprot id: B0TUN7
names: Similarity
messages: Belongs to the universal stress protein A family.

458817:SHAL RS00015
gene id: 458817:SHAL_RS00015
uniprot id: B0TLA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

458817:SHAL RS14960
gene id: 458817:SHAL_RS14960
uniprot id: B0TMT0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

458817:SHAL RS05730
gene id: 458817:SHAL_RS05730
uniprot id: B0TJA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

458817:SHAL RS10645
gene id: 458817:SHAL_RS10645
uniprot id: B0TT38
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

458817:SHAL RS07320
gene id: 458817:SHAL_RS07320
uniprot id: B0TMB9
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

458817:SHAL RS04015
gene id: 458817:SHAL_RS04015
uniprot id: B0TTL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

458817:SHAL RS12965
gene id: 458817:SHAL_RS12965
uniprot id: B0TK30
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

458817:SHAL RS02180
gene id: 458817:SHAL_RS02180
uniprot id: B0TQL4
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

458817:SHAL RS02880
gene id: 458817:SHAL_RS02880
uniprot id: B0TS07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multiheme cytochrome c family.
messages: Binds 8 heme c groups covalently per monomer.
messages: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
messages: Periplasm
messages: Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.

458817:SHAL RS07655
gene id: 458817:SHAL_RS07655
uniprot id: B0TMI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

458817:SHAL RS03430
gene id: 458817:SHAL_RS03430
uniprot id: B0TSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

458817:SHAL RS16010
gene id: 458817:SHAL_RS16010
uniprot id: B0TQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

458817:SHAL RS09780
gene id: 458817:SHAL_RS09780
uniprot id: B0TRN3
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

458817:SHAL RS05580
gene id: 458817:SHAL_RS05580
uniprot id: B0TJ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

458817:SHAL RS02455
gene id: 458817:SHAL_RS02455
uniprot id: B0TR85
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

458817:SHAL RS20730
gene id: 458817:SHAL_RS20730
uniprot id: B0TKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

458817:SHAL RS12470
gene id: 458817:SHAL_RS12470
uniprot id: B0TJF2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

458817:SHAL RS13720
gene id: 458817:SHAL_RS13720
uniprot id: B0TKZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

458817:SHAL RS05790
gene id: 458817:SHAL_RS05790
uniprot id: B0TJB9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS14385
gene id: 458817:SHAL_RS14385
uniprot id: B0TLV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

458817:SHAL RS03805
gene id: 458817:SHAL_RS03805
uniprot id: B0TTH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

458817:SHAL RS20910
gene id: 458817:SHAL_RS20910
uniprot id: B0TKK4
names: Similarity
messages: Belongs to the peptidase C40 family.

458817:SHAL RS16710
gene id: 458817:SHAL_RS16710
uniprot id: B0TR47
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

458817:SHAL RS16650
gene id: 458817:SHAL_RS16650
uniprot id: B0TR35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

458817:SHAL RS02085
gene id: 458817:SHAL_RS02085
uniprot id: B0TQJ5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS18600
gene id: 458817:SHAL_RS18600
uniprot id: B0TU29
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

458817:SHAL RS11750
gene id: 458817:SHAL_RS11750
uniprot id: B0TUT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS14060
gene id: 458817:SHAL_RS14060
uniprot id: B0TLP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS20755
gene id: 458817:SHAL_RS20755
uniprot id: B0TKH3
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS02520
gene id: 458817:SHAL_RS02520
uniprot id: B0TR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

458817:SHAL RS16495
gene id: 458817:SHAL_RS16495
uniprot id: B0TR14
names: Similarity
messages: Belongs to the UPF0234 family.

458817:SHAL RS02135
gene id: 458817:SHAL_RS02135
uniprot id: B0TQK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

458817:SHAL RS22030
gene id: 458817:SHAL_RS22030
uniprot id: B0TPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

458817:SHAL RS05665
gene id: 458817:SHAL_RS05665
uniprot id: B0TJ94
names: Similarity
messages: Belongs to the threonine synthase family.

458817:SHAL RS21810
gene id: 458817:SHAL_RS21810
uniprot id: B0TNM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

458817:SHAL RS11585
gene id: 458817:SHAL_RS11585
uniprot id: B0TUQ0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

458817:SHAL RS05555
gene id: 458817:SHAL_RS05555
uniprot id: B0TJ72
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08545
gene id: 458817:SHAL_RS08545
uniprot id: B0TP58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

458817:SHAL RS19225
gene id: 458817:SHAL_RS19225
uniprot id: B0TUZ2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

458817:SHAL RS07540
gene id: 458817:SHAL_RS07540
uniprot id: B0TMG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

458817:SHAL RS21950
gene id: 458817:SHAL_RS21950
uniprot id: B0TPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

458817:SHAL RS15895
gene id: 458817:SHAL_RS15895
uniprot id: B0TQ32
names: Similarity
messages: Belongs to the MotB family.

458817:SHAL RS13220
gene id: 458817:SHAL_RS13220
uniprot id: B0TK80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS04520
gene id: 458817:SHAL_RS04520
uniprot id: B0TUG0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS06175
gene id: 458817:SHAL_RS06175
uniprot id: B0TJZ4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

458817:SHAL RS16330
gene id: 458817:SHAL_RS16330
uniprot id: B0TQB9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

458817:SHAL RS15345
gene id: 458817:SHAL_RS15345
uniprot id: B0TP70
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

458817:SHAL RS15840
gene id: 458817:SHAL_RS15840
uniprot id: B0TPG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

458817:SHAL RS11795
gene id: 458817:SHAL_RS11795
uniprot id: B0TVD5
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

458817:SHAL RS21350
gene id: 458817:SHAL_RS21350
uniprot id: B0TM07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

458817:SHAL RS05425
gene id: 458817:SHAL_RS05425
uniprot id: B0TIU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

458817:SHAL RS14390
gene id: 458817:SHAL_RS14390
uniprot id: B0TLV5
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS04910
gene id: 458817:SHAL_RS04910
uniprot id: B0TV99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

458817:SHAL RS12340
gene id: 458817:SHAL_RS12340
uniprot id: B0TIY7
names: Similarity
messages: Belongs to the peptidase M1 family.

458817:SHAL RS01290
gene id: 458817:SHAL_RS01290
uniprot id: B0TNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS19815
gene id: 458817:SHAL_RS19815
uniprot id: B0TVS5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

458817:SHAL RS03085
gene id: 458817:SHAL_RS03085
uniprot id: B0TS42
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS20395
gene id: 458817:SHAL_RS20395
uniprot id: B0TJR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS19325
gene id: 458817:SHAL_RS19325
uniprot id: B0TV13
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

458817:SHAL RS00315
gene id: 458817:SHAL_RS00315
uniprot id: B0TM45
names: Similarity
messages: Belongs to the peptidase S33 family.

458817:SHAL RS01350
gene id: 458817:SHAL_RS01350
uniprot id: B0TNU0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS16760
gene id: 458817:SHAL_RS16760
uniprot id: B0TR57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

458817:SHAL RS02925
gene id: 458817:SHAL_RS02925
uniprot id: B0TS16
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS07960
gene id: 458817:SHAL_RS07960
uniprot id: B0TNB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS04630
gene id: 458817:SHAL_RS04630
uniprot id: B0TUI3
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

458817:SHAL RS03270
gene id: 458817:SHAL_RS03270
uniprot id: B0TS78
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

458817:SHAL RS13060
gene id: 458817:SHAL_RS13060
uniprot id: B0TK50
names: Similarity
messages: Belongs to the UPF0352 family.

458817:SHAL RS05590
gene id: 458817:SHAL_RS05590
uniprot id: B0TJ79
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

458817:SHAL RS17430
gene id: 458817:SHAL_RS17430
uniprot id: B0TRZ8
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS10225
gene id: 458817:SHAL_RS10225
uniprot id: B0TSE8
names: Similarity
messages: Belongs to the PrpF family.

458817:SHAL RS00365
gene id: 458817:SHAL_RS00365
uniprot id: B0TM54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

458817:SHAL RS13625
gene id: 458817:SHAL_RS13625
uniprot id: B0TKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

458817:SHAL RS08495
gene id: 458817:SHAL_RS08495
uniprot id: B0TP48
names: Similarity
messages: Belongs to the Gfa family.

458817:SHAL RS10830
gene id: 458817:SHAL_RS10830
uniprot id: B0TTR7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

458817:SHAL RS12895
gene id: 458817:SHAL_RS12895
uniprot id: B0TJN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS10685
gene id: 458817:SHAL_RS10685
uniprot id: B0TT46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

458817:SHAL RS05570
gene id: 458817:SHAL_RS05570
uniprot id: B0TJ75
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

458817:SHAL RS07480
gene id: 458817:SHAL_RS07480
uniprot id: B0TMF0
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

458817:SHAL RS18535
gene id: 458817:SHAL_RS18535
uniprot id: B0TU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

458817:SHAL RS15505
gene id: 458817:SHAL_RS15505
uniprot id: B0TPA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

458817:SHAL RS15380
gene id: 458817:SHAL_RS15380
uniprot id: B0TP77
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

458817:SHAL RS05080
gene id: 458817:SHAL_RS05080
uniprot id: B0TVD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

458817:SHAL RS16565
gene id: 458817:SHAL_RS16565
uniprot id: B0TR28
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

458817:SHAL RS05140
gene id: 458817:SHAL_RS05140
uniprot id: B0TIN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

458817:SHAL RS16430
gene id: 458817:SHAL_RS16430
uniprot id: B0TR01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS16750
gene id: 458817:SHAL_RS16750
uniprot id: B0TR55
names: Similarity
messages: Belongs to the UPF0250 family.

458817:SHAL RS17615
gene id: 458817:SHAL_RS17615
uniprot id: B0TSJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS04210
gene id: 458817:SHAL_RS04210
uniprot id: B0TU98
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS01160
gene id: 458817:SHAL_RS01160
uniprot id: B0TNQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

458817:SHAL RS13600
gene id: 458817:SHAL_RS13600
uniprot id: B0TKW9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

458817:SHAL RS01785
gene id: 458817:SHAL_RS01785
uniprot id: B0TPQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

458817:SHAL RS02970
gene id: 458817:SHAL_RS02970
uniprot id: B0TS25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

458817:SHAL RS17950
gene id: 458817:SHAL_RS17950
uniprot id: B0TT72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

458817:SHAL RS03235
gene id: 458817:SHAL_RS03235
uniprot id: B0TS71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

458817:SHAL RS20520
gene id: 458817:SHAL_RS20520
uniprot id: B0TJU3
names: Subcellular Location Annotation
messages: Cell outer membrane

458817:SHAL RS06350
gene id: 458817:SHAL_RS06350
uniprot id: B0TK17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

458817:SHAL RS04325
gene id: 458817:SHAL_RS04325
uniprot id: B0TUC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS15355
gene id: 458817:SHAL_RS15355
uniprot id: B0TP72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

458817:SHAL RS15270
gene id: 458817:SHAL_RS15270
uniprot id: B0TNI8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS00035
gene id: 458817:SHAL_RS00035
uniprot id: B0TLB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

458817:SHAL RS04190
gene id: 458817:SHAL_RS04190
uniprot id: B0TTQ1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

458817:SHAL RS07045
gene id: 458817:SHAL_RS07045
uniprot id: B0TLI6
names: Similarity
messages: Belongs to the YfgM family.

458817:SHAL RS18730
gene id: 458817:SHAL_RS18730
uniprot id: B0TU55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS08845
gene id: 458817:SHAL_RS08845
uniprot id: B0TPZ0
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

458817:SHAL RS11525
gene id: 458817:SHAL_RS11525
uniprot id: B0TUN8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

458817:SHAL RS07230
gene id: 458817:SHAL_RS07230
uniprot id: B0TLM1
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS03650
gene id: 458817:SHAL_RS03650
uniprot id: B0TSW2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

458817:SHAL RS05660
gene id: 458817:SHAL_RS05660
uniprot id: B0TJ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

458817:SHAL RS07370
gene id: 458817:SHAL_RS07370
uniprot id: B0TMC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

458817:SHAL RS07105
gene id: 458817:SHAL_RS07105
uniprot id: B0TLJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

458817:SHAL RS00995
gene id: 458817:SHAL_RS00995
uniprot id: B0TN61
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS02150
gene id: 458817:SHAL_RS02150
uniprot id: B0TQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

458817:SHAL RS12525
gene id: 458817:SHAL_RS12525
uniprot id: B0TJG4
names: Subcellular Location Annotation
messages: Cell inner membrane

458817:SHAL RS08270
gene id: 458817:SHAL_RS08270
uniprot id: B0TP04
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

458817:SHAL RS09395
gene id: 458817:SHAL_RS09395
uniprot id: B0TQY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

458817:SHAL RS03615
gene id: 458817:SHAL_RS03615
uniprot id: B0TSV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS16365
gene id: 458817:SHAL_RS16365
uniprot id: B0TQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

458817:SHAL RS00150
gene id: 458817:SHAL_RS00150
uniprot id: B0TLD3
names: Similarity
messages: Belongs to the Smg family.

458817:SHAL RS00030
gene id: 458817:SHAL_RS00030
uniprot id: B0TLA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

458817:SHAL RS19810
gene id: 458817:SHAL_RS19810
uniprot id: B0TVS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

458817:SHAL RS13025
gene id: 458817:SHAL_RS13025
uniprot id: B0TK43
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

458817:SHAL RS09410
gene id: 458817:SHAL_RS09410
uniprot id: B0TQY7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

458817:SHAL RS03520
gene id: 458817:SHAL_RS03520
uniprot id: B0TST7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

458817:SHAL RS05845
gene id: 458817:SHAL_RS05845
uniprot id: B0TJD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

458817:SHAL RS20790
gene id: 458817:SHAL_RS20790
uniprot id: B0TKI0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

458817:SHAL RS07395
gene id: 458817:SHAL_RS07395
uniprot id: B0TMD4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

458817:SHAL RS22130
gene id: 458817:SHAL_RS22130
uniprot id: B0TQD3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS10060
gene id: 458817:SHAL_RS10060
uniprot id: B0TSC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

458817:SHAL RS01330
gene id: 458817:SHAL_RS01330
uniprot id: B0TNT6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS18515
gene id: 458817:SHAL_RS18515
uniprot id: B0TU12
names: Similarity
messages: Belongs to the UPF0111 family.

458817:SHAL RS13495
gene id: 458817:SHAL_RS13495
uniprot id: B0TKU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

458817:SHAL RS14170
gene id: 458817:SHAL_RS14170
uniprot id: B0TLR4
names: Similarity
messages: Belongs to the UPF0319 family.

458817:SHAL RS15320
gene id: 458817:SHAL_RS15320
uniprot id: B0TNJ8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

458817:SHAL RS16260
gene id: 458817:SHAL_RS16260
uniprot id: B0TQA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS01410
gene id: 458817:SHAL_RS01410
uniprot id: B0TNV2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS09430
gene id: 458817:SHAL_RS09430
uniprot id: B0TQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

458817:SHAL RS15680
gene id: 458817:SHAL_RS15680
uniprot id: B0TPD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

458817:SHAL RS21820
gene id: 458817:SHAL_RS21820
uniprot id: B0TNM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

458817:SHAL RS15530
gene id: 458817:SHAL_RS15530
uniprot id: B0TPA5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS17220
gene id: 458817:SHAL_RS17220
uniprot id: B0TRV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

458817:SHAL RS07730
gene id: 458817:SHAL_RS07730
uniprot id: B0TN84
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

458817:SHAL RS22270
gene id: 458817:SHAL_RS22270
uniprot id: B0TQG1
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS18270
gene id: 458817:SHAL_RS18270
uniprot id: B0TTD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

458817:SHAL RS12245
gene id: 458817:SHAL_RS12245
uniprot id: B0TIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

458817:SHAL RS20150
gene id: 458817:SHAL_RS20150
uniprot id: B0TJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

458817:SHAL RS03220
gene id: 458817:SHAL_RS03220
uniprot id: B0TS68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

458817:SHAL RS06215
gene id: 458817:SHAL_RS06215
uniprot id: B0TK00
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

458817:SHAL RS14995
gene id: 458817:SHAL_RS14995
uniprot id: B0TMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

458817:SHAL RS21685
gene id: 458817:SHAL_RS21685
uniprot id: B0TMY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

458817:SHAL RS19005
gene id: 458817:SHAL_RS19005
uniprot id: B0TUU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

458817:SHAL RS09825
gene id: 458817:SHAL_RS09825
uniprot id: B0TRP2
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS14660
gene id: 458817:SHAL_RS14660
uniprot id: B0TMM2
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS05340
gene id: 458817:SHAL_RS05340
uniprot id: B0TIS5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

458817:SHAL RS21615
gene id: 458817:SHAL_RS21615
uniprot id: B0TMX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

458817:SHAL RS11970
gene id: 458817:SHAL_RS11970
uniprot id: B0TVG9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS04145
gene id: 458817:SHAL_RS04145
uniprot id: B0TTP2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS03500
gene id: 458817:SHAL_RS03500
uniprot id: B0TST3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

458817:SHAL RS20055
gene id: 458817:SHAL_RS20055
uniprot id: B0TJ23
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

458817:SHAL RS04965
gene id: 458817:SHAL_RS04965
uniprot id: B0TVB0
names: Similarity
messages: Belongs to the peptidase M24B family.

458817:SHAL RS02540
gene id: 458817:SHAL_RS02540
uniprot id: B0TRA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

458817:SHAL RS02825
gene id: 458817:SHAL_RS02825
uniprot id: B0TRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

458817:SHAL RS22005
gene id: 458817:SHAL_RS22005
uniprot id: B0TPJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

458817:SHAL RS01090
gene id: 458817:SHAL_RS01090
uniprot id: B0TN80
names: Function
messages: Could be a 3Fe-4S cluster-containing protein.

458817:SHAL RS20160
gene id: 458817:SHAL_RS20160
uniprot id: B0TJ39
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

458817:SHAL RS03055
gene id: 458817:SHAL_RS03055
uniprot id: B0TS36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

458817:SHAL RS21640
gene id: 458817:SHAL_RS21640
uniprot id: B0TMY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

458817:SHAL RS14210
gene id: 458817:SHAL_RS14210
uniprot id: B0TLS2
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

458817:SHAL RS03455
gene id: 458817:SHAL_RS03455
uniprot id: B0TSS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

458817:SHAL RS00375
gene id: 458817:SHAL_RS00375
uniprot id: B0TM56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

458817:SHAL RS07470
gene id: 458817:SHAL_RS07470
uniprot id: B0TME8
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS12295
gene id: 458817:SHAL_RS12295
uniprot id: B0TIX8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

458817:SHAL RS17110
gene id: 458817:SHAL_RS17110
uniprot id: B0TRT6
names: Activity Regulation
names: Caution
names: Domain
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

458817:SHAL RS09970
gene id: 458817:SHAL_RS09970
uniprot id: B0TSA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

458817:SHAL RS20265
gene id: 458817:SHAL_RS20265
uniprot id: B0TJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

458817:SHAL RS21540
gene id: 458817:SHAL_RS21540
uniprot id: B0TMW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

458817:SHAL RS01525
gene id: 458817:SHAL_RS01525
uniprot id: B0TNX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

458817:SHAL RS12955
gene id: 458817:SHAL_RS12955
uniprot id: B0TK28
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

458817:SHAL RS02565
gene id: 458817:SHAL_RS02565
uniprot id: B0TRA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS19455
gene id: 458817:SHAL_RS19455
uniprot id: B0TV36
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS20335
gene id: 458817:SHAL_RS20335
uniprot id: B0TJQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

458817:SHAL RS11660
gene id: 458817:SHAL_RS11660
uniprot id: B0TUR5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

458817:SHAL RS19050
gene id: 458817:SHAL_RS19050
uniprot id: B0TUV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

458817:SHAL RS06375
gene id: 458817:SHAL_RS06375
uniprot id: B0TK22
names: Similarity
messages: Belongs to the peptidase M16 family.

458817:SHAL RS17930
gene id: 458817:SHAL_RS17930
uniprot id: B0TT68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

458817:SHAL RS18805
gene id: 458817:SHAL_RS18805
uniprot id: B0TU69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS01405
gene id: 458817:SHAL_RS01405
uniprot id: B0TNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

458817:SHAL RS20200
gene id: 458817:SHAL_RS20200
uniprot id: B0TJ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

458817:SHAL RS19390
gene id: 458817:SHAL_RS19390
uniprot id: B0TV24
names: Similarity
messages: Belongs to the UPF0053 family.

458817:SHAL RS18645
gene id: 458817:SHAL_RS18645
uniprot id: B0TU38
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

458817:SHAL RS18315
gene id: 458817:SHAL_RS18315
uniprot id: B0TTE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS12300
gene id: 458817:SHAL_RS12300
uniprot id: B0TIX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

458817:SHAL RS22250
gene id: 458817:SHAL_RS22250
uniprot id: B0TQF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

458817:SHAL RS04650
gene id: 458817:SHAL_RS04650
uniprot id: B0TV49
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

458817:SHAL RS20800
gene id: 458817:SHAL_RS20800
uniprot id: B0TKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

458817:SHAL RS03180
gene id: 458817:SHAL_RS03180
uniprot id: B0TS60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS22275
gene id: 458817:SHAL_RS22275
uniprot id: B0TQG2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

458817:SHAL RS00640
gene id: 458817:SHAL_RS00640
uniprot id: B0TMA9
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

458817:SHAL RS16850
gene id: 458817:SHAL_RS16850
uniprot id: B0TR67
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

458817:SHAL RS12975
gene id: 458817:SHAL_RS12975
uniprot id: B0TK32
names: Similarity
messages: Belongs to the citrate synthase family.

458817:SHAL RS18480
gene id: 458817:SHAL_RS18480
uniprot id: B0TU05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS08935
gene id: 458817:SHAL_RS08935
uniprot id: B0TQ08
names: Similarity
messages: Belongs to the ClpA/ClpB family.

458817:SHAL RS21135
gene id: 458817:SHAL_RS21135
uniprot id: B0TL87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

458817:SHAL RS06925
gene id: 458817:SHAL_RS06925
uniprot id: B0TLG3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

458817:SHAL RS16740
gene id: 458817:SHAL_RS16740
uniprot id: B0TR53
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

458817:SHAL RS14285
gene id: 458817:SHAL_RS14285
uniprot id: B0TLT7
names: Similarity
messages: Belongs to the PspA/IM30 family.

458817:SHAL RS18655
gene id: 458817:SHAL_RS18655
uniprot id: B0TU40
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

458817:SHAL RS04680
gene id: 458817:SHAL_RS04680
uniprot id: B0TV55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

458817:SHAL RS01960
gene id: 458817:SHAL_RS01960
uniprot id: B0TPU2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS09940
gene id: 458817:SHAL_RS09940
uniprot id: B0TSA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS13945
gene id: 458817:SHAL_RS13945
uniprot id: B0TL40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

458817:SHAL RS17155
gene id: 458817:SHAL_RS17155
uniprot id: B0TRU5
names: Similarity
messages: Belongs to the peptidase M13 family.

458817:SHAL RS17375
gene id: 458817:SHAL_RS17375
uniprot id: B0TRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS01660
gene id: 458817:SHAL_RS01660
uniprot id: B0TPN3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

458817:SHAL RS16045
gene id: 458817:SHAL_RS16045
uniprot id: B0TQ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

458817:SHAL RS11800
gene id: 458817:SHAL_RS11800
uniprot id: B0TVD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

458817:SHAL RS05980
gene id: 458817:SHAL_RS05980
uniprot id: B0TJV5
names: Similarity
messages: Belongs to the GSP E family.

458817:SHAL RS16885
gene id: 458817:SHAL_RS16885
uniprot id: B0TR74
names: Similarity
messages: Belongs to the peptidase M13 family.

458817:SHAL RS12155
gene id: 458817:SHAL_RS12155
uniprot id: B0TVK6
names: Similarity
messages: Belongs to the DnaA family.

458817:SHAL RS10445
gene id: 458817:SHAL_RS10445
uniprot id: B0TT08
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

458817:SHAL RS09245
gene id: 458817:SHAL_RS09245
uniprot id: B0TQV3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

458817:SHAL RS20035
gene id: 458817:SHAL_RS20035
uniprot id: B0TJ19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

458817:SHAL RS21825
gene id: 458817:SHAL_RS21825
uniprot id: B0TNM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

458817:SHAL RS05725
gene id: 458817:SHAL_RS05725
uniprot id: B0TJA6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

458817:SHAL RS04510
gene id: 458817:SHAL_RS04510
uniprot id: B0TUF8
names: Similarity
messages: Belongs to the UPF0231 family.

458817:SHAL RS11555
gene id: 458817:SHAL_RS11555
uniprot id: B0TUP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

458817:SHAL RS15805
gene id: 458817:SHAL_RS15805
uniprot id: B0TPG0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

458817:SHAL RS11180
gene id: 458817:SHAL_RS11180
uniprot id: B0TTY2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

458817:SHAL RS21695
gene id: 458817:SHAL_RS21695
uniprot id: B0TMZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

458817:SHAL RS00095
gene id: 458817:SHAL_RS00095
uniprot id: B0TLC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

458817:SHAL RS15810
gene id: 458817:SHAL_RS15810
uniprot id: B0TPG1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS00275
gene id: 458817:SHAL_RS00275
uniprot id: B0TM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS10680
gene id: 458817:SHAL_RS10680
uniprot id: B0TT45
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

458817:SHAL RS05175
gene id: 458817:SHAL_RS05175
uniprot id: B0TIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

458817:SHAL RS10370
gene id: 458817:SHAL_RS10370
uniprot id: B0TSZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

458817:SHAL RS18885
gene id: 458817:SHAL_RS18885
uniprot id: B0TU80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

458817:SHAL RS00895
gene id: 458817:SHAL_RS00895
uniprot id: B0TN40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

458817:SHAL RS17410
gene id: 458817:SHAL_RS17410
uniprot id: B0TRZ4
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS04130
gene id: 458817:SHAL_RS04130
uniprot id: B0TTN9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

458817:SHAL RS04605
gene id: 458817:SHAL_RS04605
uniprot id: B0TUH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

458817:SHAL RS16420
gene id: 458817:SHAL_RS16420
uniprot id: B0TQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS04670
gene id: 458817:SHAL_RS04670
uniprot id: B0TV53
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

458817:SHAL RS09145
gene id: 458817:SHAL_RS09145
uniprot id: B0TQT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

458817:SHAL RS18475
gene id: 458817:SHAL_RS18475
uniprot id: B0TU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

458817:SHAL RS12515
gene id: 458817:SHAL_RS12515
uniprot id: B0TJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

458817:SHAL RS19180
gene id: 458817:SHAL_RS19180
uniprot id: B0TUY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

458817:SHAL RS20745
gene id: 458817:SHAL_RS20745
uniprot id: B0TKH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

458817:SHAL RS18750
gene id: 458817:SHAL_RS18750
uniprot id: B0TU59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

458817:SHAL RS02555
gene id: 458817:SHAL_RS02555
uniprot id: B0TRA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

458817:SHAL RS11310
gene id: 458817:SHAL_RS11310
uniprot id: B0TUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

458817:SHAL RS09995
gene id: 458817:SHAL_RS09995
uniprot id: B0TSB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

458817:SHAL RS21935
gene id: 458817:SHAL_RS21935
uniprot id: B0TPH7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

458817:SHAL RS18945
gene id: 458817:SHAL_RS18945
uniprot id: B0TU92
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS21145
gene id: 458817:SHAL_RS21145
uniprot id: B0TL89
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

458817:SHAL RS19155
gene id: 458817:SHAL_RS19155
uniprot id: B0TUX8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

458817:SHAL RS15425
gene id: 458817:SHAL_RS15425
uniprot id: B0TP86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

458817:SHAL RS05740
gene id: 458817:SHAL_RS05740
uniprot id: B0TJA9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

458817:SHAL RS22285
gene id: 458817:SHAL_RS22285
uniprot id: B0TQG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

458817:SHAL RS00380
gene id: 458817:SHAL_RS00380
uniprot id: B0TM57
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

458817:SHAL RS06380
gene id: 458817:SHAL_RS06380
uniprot id: B0TK23
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

458817:SHAL RS17820
gene id: 458817:SHAL_RS17820
uniprot id: B0TSN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS10675
gene id: 458817:SHAL_RS10675
uniprot id: B0TT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

458817:SHAL RS16905
gene id: 458817:SHAL_RS16905
uniprot id: B0TR78
names: Similarity
messages: Belongs to the GST superfamily.

458817:SHAL RS07365
gene id: 458817:SHAL_RS07365
uniprot id: B0TMC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

458817:SHAL RS15870
gene id: 458817:SHAL_RS15870
uniprot id: B0TQ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

458817:SHAL RS17045
gene id: 458817:SHAL_RS17045
uniprot id: B0TRS4
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS17100
gene id: 458817:SHAL_RS17100
uniprot id: B0TRT4
names: Similarity
messages: Belongs to the glutamate synthase family.

458817:SHAL RS20555
gene id: 458817:SHAL_RS20555
uniprot id: B0TKD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

458817:SHAL RS08140
gene id: 458817:SHAL_RS08140
uniprot id: B0TNE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS22085
gene id: 458817:SHAL_RS22085
uniprot id: B0TPK7
names: Similarity
messages: Belongs to the MotB family.

458817:SHAL RS15340
gene id: 458817:SHAL_RS15340
uniprot id: B0TP69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

458817:SHAL RS09615
gene id: 458817:SHAL_RS09615
uniprot id: B0TRK4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

458817:SHAL RS17485
gene id: 458817:SHAL_RS17485
uniprot id: B0TSG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

458817:SHAL RS13160
gene id: 458817:SHAL_RS13160
uniprot id: B0TK68
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

458817:SHAL RS21235
gene id: 458817:SHAL_RS21235
uniprot id: B0TLA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

458817:SHAL RS20815
gene id: 458817:SHAL_RS20815
uniprot id: B0TKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS06240
gene id: 458817:SHAL_RS06240
uniprot id: B0TK05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

458817:SHAL RS21375
gene id: 458817:SHAL_RS21375
uniprot id: B0TM12
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

458817:SHAL RS03985
gene id: 458817:SHAL_RS03985
uniprot id: B0TTL0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

458817:SHAL RS04205
gene id: 458817:SHAL_RS04205
uniprot id: B0TTQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

458817:SHAL RS19145
gene id: 458817:SHAL_RS19145
uniprot id: B0TUX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

458817:SHAL RS16675
gene id: 458817:SHAL_RS16675
uniprot id: B0TR40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

458817:SHAL RS00405
gene id: 458817:SHAL_RS00405
uniprot id: B0TM62
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

458817:SHAL RS12285
gene id: 458817:SHAL_RS12285
uniprot id: B0TIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

458817:SHAL RS03165
gene id: 458817:SHAL_RS03165
uniprot id: B0TS57
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

458817:SHAL RS14125
gene id: 458817:SHAL_RS14125
uniprot id: B0TLQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

458817:SHAL RS15920
gene id: 458817:SHAL_RS15920
uniprot id: B0TQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

458817:SHAL RS05415
gene id: 458817:SHAL_RS05415
uniprot id: B0TIU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

458817:SHAL RS09535
gene id: 458817:SHAL_RS09535
uniprot id: B0TRI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

458817:SHAL RS15715
gene id: 458817:SHAL_RS15715
uniprot id: B0TPE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

458817:SHAL RS01010
gene id: 458817:SHAL_RS01010
uniprot id: B0TN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS03170
gene id: 458817:SHAL_RS03170
uniprot id: B0TS58
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS12875
gene id: 458817:SHAL_RS12875
uniprot id: B0TJN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS10570
gene id: 458817:SHAL_RS10570
uniprot id: B0TT23
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

458817:SHAL RS15770
gene id: 458817:SHAL_RS15770
uniprot id: B0TPF2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

458817:SHAL RS05970
gene id: 458817:SHAL_RS05970
uniprot id: B0TJV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

458817:SHAL RS21670
gene id: 458817:SHAL_RS21670
uniprot id: B0TMY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

458817:SHAL RS11735
gene id: 458817:SHAL_RS11735
uniprot id: B0TUT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS04825
gene id: 458817:SHAL_RS04825
uniprot id: B0TV82
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08690
gene id: 458817:SHAL_RS08690
uniprot id: B0TPW6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

458817:SHAL RS05705
gene id: 458817:SHAL_RS05705
uniprot id: B0TJA2
names: Similarity
messages: Belongs to the XFP family.

458817:SHAL RS07560
gene id: 458817:SHAL_RS07560
uniprot id: B0TMG6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

458817:SHAL RS20715
gene id: 458817:SHAL_RS20715
uniprot id: B0TKG5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

458817:SHAL RS01675
gene id: 458817:SHAL_RS01675
uniprot id: B0TPN6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

458817:SHAL RS04810
gene id: 458817:SHAL_RS04810
uniprot id: B0TV79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

458817:SHAL RS07450
gene id: 458817:SHAL_RS07450
uniprot id: B0TME4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

458817:SHAL RS21230
gene id: 458817:SHAL_RS21230
uniprot id: B0TLA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

458817:SHAL RS19505
gene id: 458817:SHAL_RS19505
uniprot id: B0TV46
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

458817:SHAL RS00755
gene id: 458817:SHAL_RS00755
uniprot id: B0TN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS03525
gene id: 458817:SHAL_RS03525
uniprot id: B0TST8
names: Similarity
messages: Belongs to the carbamate kinase family.

458817:SHAL RS11755
gene id: 458817:SHAL_RS11755
uniprot id: B0TUT4
names: Cofactor
messages: Can also use Mn(2+) ion.

458817:SHAL RS17480
gene id: 458817:SHAL_RS17480
uniprot id: B0TSG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

458817:SHAL RS00170
gene id: 458817:SHAL_RS00170
uniprot id: B0TLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

458817:SHAL RS11790
gene id: 458817:SHAL_RS11790
uniprot id: B0TUU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS06125
gene id: 458817:SHAL_RS06125
uniprot id: B0TJY4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

458817:SHAL RS21150
gene id: 458817:SHAL_RS21150
uniprot id: B0TL90
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

458817:SHAL RS17625
gene id: 458817:SHAL_RS17625
uniprot id: B0TSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

458817:SHAL RS13480
gene id: 458817:SHAL_RS13480
uniprot id: B0TKC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS03365
gene id: 458817:SHAL_RS03365
uniprot id: B0TSQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

458817:SHAL RS15890
gene id: 458817:SHAL_RS15890
uniprot id: B0TQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

458817:SHAL RS18000
gene id: 458817:SHAL_RS18000
uniprot id: B0TT83
names: Cofactor
messages: Binds 1 zinc ion per subunit.

458817:SHAL RS19300
gene id: 458817:SHAL_RS19300
uniprot id: B0TV08
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

458817:SHAL RS10985
gene id: 458817:SHAL_RS10985
uniprot id: B0TTU3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS21370
gene id: 458817:SHAL_RS21370
uniprot id: B0TM11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

458817:SHAL RS12980
gene id: 458817:SHAL_RS12980
uniprot id: B0TK33
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS00955
gene id: 458817:SHAL_RS00955
uniprot id: B0TN53
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS07855
gene id: 458817:SHAL_RS07855
uniprot id: B0TNA9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

458817:SHAL RS07490
gene id: 458817:SHAL_RS07490
uniprot id: B0TMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

458817:SHAL RS09830
gene id: 458817:SHAL_RS09830
uniprot id: B0TRP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

458817:SHAL RS16320
gene id: 458817:SHAL_RS16320
uniprot id: B0TQB7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

458817:SHAL RS08700
gene id: 458817:SHAL_RS08700
uniprot id: B0TPW8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

458817:SHAL RS13995
gene id: 458817:SHAL_RS13995
uniprot id: B0TL50
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS16415
gene id: 458817:SHAL_RS16415
uniprot id: B0TQZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

458817:SHAL RS00110
gene id: 458817:SHAL_RS00110
uniprot id: B0TLC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

458817:SHAL RS18340
gene id: 458817:SHAL_RS18340
uniprot id: B0TTE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

458817:SHAL RS21400
gene id: 458817:SHAL_RS21400
uniprot id: B0TM17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

458817:SHAL RS13300
gene id: 458817:SHAL_RS13300
uniprot id: B0TK93
names: Similarity
messages: Belongs to the proline racemase family.

458817:SHAL RS06030
gene id: 458817:SHAL_RS06030
uniprot id: B0TJW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS19930
gene id: 458817:SHAL_RS19930
uniprot id: B0TVU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

458817:SHAL RS12870
gene id: 458817:SHAL_RS12870
uniprot id: B0TJN4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

458817:SHAL RS01500
gene id: 458817:SHAL_RS01500
uniprot id: B0TNX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS16170
gene id: 458817:SHAL_RS16170
uniprot id: B0TQ89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

458817:SHAL RS16360
gene id: 458817:SHAL_RS16360
uniprot id: B0TQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

458817:SHAL RS14155
gene id: 458817:SHAL_RS14155
uniprot id: B0TLR1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS22325
gene id: 458817:SHAL_RS22325
uniprot id: B0TQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

458817:SHAL RS04675
gene id: 458817:SHAL_RS04675
uniprot id: B0TV54
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

458817:SHAL RS07065
gene id: 458817:SHAL_RS07065
uniprot id: B0TLJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

458817:SHAL RS21990
gene id: 458817:SHAL_RS21990
uniprot id: B0TPI8
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

458817:SHAL RS04800
gene id: 458817:SHAL_RS04800
uniprot id: B0TV78
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

458817:SHAL RS16505
gene id: 458817:SHAL_RS16505
uniprot id: B0TR16
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

458817:SHAL RS11315
gene id: 458817:SHAL_RS11315
uniprot id: B0TUK0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

458817:SHAL RS07460
gene id: 458817:SHAL_RS07460
uniprot id: B0TME6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

458817:SHAL RS01070
gene id: 458817:SHAL_RS01070
uniprot id: B0TN76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

458817:SHAL RS15990
gene id: 458817:SHAL_RS15990
uniprot id: B0TQ52
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

458817:SHAL RS03790
gene id: 458817:SHAL_RS03790
uniprot id: B0TTH1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

458817:SHAL RS01445
gene id: 458817:SHAL_RS01445
uniprot id: B0TNW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

458817:SHAL RS11910
gene id: 458817:SHAL_RS11910
uniprot id: B0TVF8
names: Similarity
messages: Belongs to the peptidase A24 family.

458817:SHAL RS17490
gene id: 458817:SHAL_RS17490
uniprot id: B0TSG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

458817:SHAL RS16970
gene id: 458817:SHAL_RS16970
uniprot id: B0TRR0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

458817:SHAL RS21070
gene id: 458817:SHAL_RS21070
uniprot id: B0TL74
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

458817:SHAL RS11610
gene id: 458817:SHAL_RS11610
uniprot id: B0TUQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS05755
gene id: 458817:SHAL_RS05755
uniprot id: B0TJB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

458817:SHAL RS16765
gene id: 458817:SHAL_RS16765
uniprot id: B0TR58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

458817:SHAL RS18955
gene id: 458817:SHAL_RS18955
uniprot id: B0TU94
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

458817:SHAL RS07705
gene id: 458817:SHAL_RS07705
uniprot id: B0TMJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS07510
gene id: 458817:SHAL_RS07510
uniprot id: B0TMF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

458817:SHAL RS09210
gene id: 458817:SHAL_RS09210
uniprot id: B0TQU6
names: Similarity
messages: Belongs to the fabD family.

458817:SHAL RS09420
gene id: 458817:SHAL_RS09420
uniprot id: B0TQY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

458817:SHAL RS02140
gene id: 458817:SHAL_RS02140
uniprot id: B0TQK6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

458817:SHAL RS11030
gene id: 458817:SHAL_RS11030
uniprot id: B0TTV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS22145
gene id: 458817:SHAL_RS22145
uniprot id: B0TQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

458817:SHAL RS00645
gene id: 458817:SHAL_RS00645
uniprot id: B0TMB0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

458817:SHAL RS06155
gene id: 458817:SHAL_RS06155
uniprot id: B0TJZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

458817:SHAL RS02155
gene id: 458817:SHAL_RS02155
uniprot id: B0TQK9
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

458817:SHAL RS08925
gene id: 458817:SHAL_RS08925
uniprot id: B0TQ06
names: Subcellular Location Annotation
messages: Cytoplasm

458817:SHAL RS02255
gene id: 458817:SHAL_RS02255
uniprot id: B0TQM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

458817:SHAL RS01260
gene id: 458817:SHAL_RS01260
uniprot id: B0TNS3
names: Similarity
messages: Belongs to the SCO1/2 family.

458817:SHAL RS20235
gene id: 458817:SHAL_RS20235
uniprot id: B0TJ55
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

458817:SHAL RS19055
gene id: 458817:SHAL_RS19055
uniprot id: B0TUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

458817:SHAL RS02310
gene id: 458817:SHAL_RS02310
uniprot id: B0TQP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

458817:SHAL RS08070
gene id: 458817:SHAL_RS08070
uniprot id: B0TND3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

458817:SHAL RS15615
gene id: 458817:SHAL_RS15615
uniprot id: B0TPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS18125
gene id: 458817:SHAL_RS18125
uniprot id: B0TTA6
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS06585
gene id: 458817:SHAL_RS06585
uniprot id: B0TKP9
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

458817:SHAL RS00235
gene id: 458817:SHAL_RS00235
uniprot id: B0TLE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

458817:SHAL RS00090
gene id: 458817:SHAL_RS00090
uniprot id: B0TLC1
names: Similarity
messages: Belongs to the IMPACT family.

458817:SHAL RS04540
gene id: 458817:SHAL_RS04540
uniprot id: B0TUG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

458817:SHAL RS10155
gene id: 458817:SHAL_RS10155
uniprot id: B0TSD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

458817:SHAL RS13115
gene id: 458817:SHAL_RS13115
uniprot id: B0TK60
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS17925
gene id: 458817:SHAL_RS17925
uniprot id: B0TT67
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

458817:SHAL RS04905
gene id: 458817:SHAL_RS04905
uniprot id: B0TV98
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08850
gene id: 458817:SHAL_RS08850
uniprot id: B0TPZ1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

458817:SHAL RS01490
gene id: 458817:SHAL_RS01490
uniprot id: B0TNW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

458817:SHAL RS16715
gene id: 458817:SHAL_RS16715
uniprot id: B0TR48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

458817:SHAL RS17395
gene id: 458817:SHAL_RS17395
uniprot id: B0TRZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS18850
gene id: 458817:SHAL_RS18850
uniprot id: B0TU73
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

458817:SHAL RS17825
gene id: 458817:SHAL_RS17825
uniprot id: B0TSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS21985
gene id: 458817:SHAL_RS21985
uniprot id: B0TPI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

458817:SHAL RS11840
gene id: 458817:SHAL_RS11840
uniprot id: B0TVE4
names: Similarity
messages: Belongs to the HypE family.

458817:SHAL RS00410
gene id: 458817:SHAL_RS00410
uniprot id: B0TM63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS11300
gene id: 458817:SHAL_RS11300
uniprot id: B0TUJ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS11140
gene id: 458817:SHAL_RS11140
uniprot id: B0TTX4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

458817:SHAL RS03255
gene id: 458817:SHAL_RS03255
uniprot id: B0TS75
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

458817:SHAL RS10870
gene id: 458817:SHAL_RS10870
uniprot id: B0TTS2
names: Similarity
messages: Belongs to the DsrF/TusC family.

458817:SHAL RS01970
gene id: 458817:SHAL_RS01970
uniprot id: B0TPU4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

458817:SHAL RS18790
gene id: 458817:SHAL_RS18790
uniprot id: B0TU66
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

458817:SHAL RS05135
gene id: 458817:SHAL_RS05135
uniprot id: B0TIN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

458817:SHAL RS05910
gene id: 458817:SHAL_RS05910
uniprot id: B0TJD7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS03410
gene id: 458817:SHAL_RS03410
uniprot id: B0TSR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

458817:SHAL RS12060
gene id: 458817:SHAL_RS12060
uniprot id: B0TVI7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

458817:SHAL RS02315
gene id: 458817:SHAL_RS02315
uniprot id: B0TQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

458817:SHAL RS20270
gene id: 458817:SHAL_RS20270
uniprot id: B0TJ62
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

458817:SHAL RS20025
gene id: 458817:SHAL_RS20025
uniprot id: B0TJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

458817:SHAL RS02115
gene id: 458817:SHAL_RS02115
uniprot id: B0TQK1
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

458817:SHAL RS14320
gene id: 458817:SHAL_RS14320
uniprot id: B0TLU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

458817:SHAL RS20710
gene id: 458817:SHAL_RS20710
uniprot id: B0TKG4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS04865
gene id: 458817:SHAL_RS04865
uniprot id: B0TV90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

458817:SHAL RS17495
gene id: 458817:SHAL_RS17495
uniprot id: B0TSG8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

458817:SHAL RS11835
gene id: 458817:SHAL_RS11835
uniprot id: B0TVE3
names: Similarity
messages: Belongs to the HypD family.

458817:SHAL RS04970
gene id: 458817:SHAL_RS04970
uniprot id: B0TVB1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

458817:SHAL RS19135
gene id: 458817:SHAL_RS19135
uniprot id: B0TUX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

458817:SHAL RS11855
gene id: 458817:SHAL_RS11855
uniprot id: B0TVE7
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS08815
gene id: 458817:SHAL_RS08815
uniprot id: B0TPY4
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

458817:SHAL RS07350
gene id: 458817:SHAL_RS07350
uniprot id: B0TMC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

458817:SHAL RS09665
gene id: 458817:SHAL_RS09665
uniprot id: B0TRL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

458817:SHAL RS15545
gene id: 458817:SHAL_RS15545
uniprot id: B0TPA8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

458817:SHAL RS11565
gene id: 458817:SHAL_RS11565
uniprot id: B0TUP6
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

458817:SHAL RS14245
gene id: 458817:SHAL_RS14245
uniprot id: B0TLS9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

458817:SHAL RS08205
gene id: 458817:SHAL_RS08205
uniprot id: B0TNZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

458817:SHAL RS17550
gene id: 458817:SHAL_RS17550
uniprot id: B0TSH8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

458817:SHAL RS18765
gene id: 458817:SHAL_RS18765
uniprot id: B0TU61
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

458817:SHAL RS18740
gene id: 458817:SHAL_RS18740
uniprot id: B0TU57
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

458817:SHAL RS16355
gene id: 458817:SHAL_RS16355
uniprot id: B0TQC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

458817:SHAL RS05985
gene id: 458817:SHAL_RS05985
uniprot id: B0TJV6
names: Similarity
messages: Belongs to the GSP E family.

458817:SHAL RS06280
gene id: 458817:SHAL_RS06280
uniprot id: B0TK13
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

458817:SHAL RS17690
gene id: 458817:SHAL_RS17690
uniprot id: B0TSK7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Exported by the Tat system.
messages: Periplasm
messages: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

458817:SHAL RS09440
gene id: 458817:SHAL_RS09440
uniprot id: B0TRH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

458817:SHAL RS04185
gene id: 458817:SHAL_RS04185
uniprot id: B0TTQ0
names: Similarity
messages: Belongs to the SufE family.

458817:SHAL RS20260
gene id: 458817:SHAL_RS20260
uniprot id: B0TJ60
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS15410
gene id: 458817:SHAL_RS15410
uniprot id: B0TP83
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

458817:SHAL RS14655
gene id: 458817:SHAL_RS14655
uniprot id: B0TMM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

458817:SHAL RS19000
gene id: 458817:SHAL_RS19000
uniprot id: B0TUU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

458817:SHAL RS09990
gene id: 458817:SHAL_RS09990
uniprot id: B0TSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

458817:SHAL RS02695
gene id: 458817:SHAL_RS02695
uniprot id: B0TRD3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS09850
gene id: 458817:SHAL_RS09850
uniprot id: B0TRP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

458817:SHAL RS02335
gene id: 458817:SHAL_RS02335
uniprot id: B0TQP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

458817:SHAL RS14985
gene id: 458817:SHAL_RS14985
uniprot id: B0TMT5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

458817:SHAL RS15295
gene id: 458817:SHAL_RS15295
uniprot id: B0TNJ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

458817:SHAL RS07895
gene id: 458817:SHAL_RS07895
uniprot id: B0TNB7
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS16230
gene id: 458817:SHAL_RS16230
uniprot id: B0TQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

458817:SHAL RS08585
gene id: 458817:SHAL_RS08585
uniprot id: B0TP67
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

458817:SHAL RS03595
gene id: 458817:SHAL_RS03595
uniprot id: B0TSV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

458817:SHAL RS01950
gene id: 458817:SHAL_RS01950
uniprot id: B0TPU0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS20750
gene id: 458817:SHAL_RS20750
uniprot id: B0TKH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS05885
gene id: 458817:SHAL_RS05885
uniprot id: B0TJD2
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

458817:SHAL RS20215
gene id: 458817:SHAL_RS20215
uniprot id: B0TJ50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

458817:SHAL RS13785
gene id: 458817:SHAL_RS13785
uniprot id: B0TL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

458817:SHAL RS21380
gene id: 458817:SHAL_RS21380
uniprot id: B0TM13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

458817:SHAL RS02465
gene id: 458817:SHAL_RS02465
uniprot id: B0TR87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS01200
gene id: 458817:SHAL_RS01200
uniprot id: B0TNR1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS02025
gene id: 458817:SHAL_RS02025
uniprot id: B0TQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS18685
gene id: 458817:SHAL_RS18685
uniprot id: B0TU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

458817:SHAL RS18505
gene id: 458817:SHAL_RS18505
uniprot id: B0TU10
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS20995
gene id: 458817:SHAL_RS20995
uniprot id: B0TL59
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

458817:SHAL RS01055
gene id: 458817:SHAL_RS01055
uniprot id: B0TN73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

458817:SHAL RS21265
gene id: 458817:SHAL_RS21265
uniprot id: B0TLZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

458817:SHAL RS12600
gene id: 458817:SHAL_RS12600
uniprot id: B0TJI2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

458817:SHAL RS17360
gene id: 458817:SHAL_RS17360
uniprot id: B0TRY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

458817:SHAL RS02525
gene id: 458817:SHAL_RS02525
uniprot id: B0TR99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

458817:SHAL RS08530
gene id: 458817:SHAL_RS08530
uniprot id: B0TP55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS00490
gene id: 458817:SHAL_RS00490
uniprot id: B0TM79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

458817:SHAL RS02545
gene id: 458817:SHAL_RS02545
uniprot id: B0TRA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

458817:SHAL RS05475
gene id: 458817:SHAL_RS05475
uniprot id: B0TIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

458817:SHAL RS11125
gene id: 458817:SHAL_RS11125
uniprot id: B0TTX1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

458817:SHAL RS20125
gene id: 458817:SHAL_RS20125
uniprot id: B0TJ32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS15385
gene id: 458817:SHAL_RS15385
uniprot id: B0TP78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

458817:SHAL RS15555
gene id: 458817:SHAL_RS15555
uniprot id: B0TPB0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

458817:SHAL RS06420
gene id: 458817:SHAL_RS06420
uniprot id: B0TKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

458817:SHAL RS16755
gene id: 458817:SHAL_RS16755
uniprot id: B0TR56
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

458817:SHAL RS10670
gene id: 458817:SHAL_RS10670
uniprot id: B0TT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

458817:SHAL RS07745
gene id: 458817:SHAL_RS07745
uniprot id: B0TN87
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

458817:SHAL RS02460
gene id: 458817:SHAL_RS02460
uniprot id: B0TR86
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

458817:SHAL RS16425
gene id: 458817:SHAL_RS16425
uniprot id: B0TR00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

458817:SHAL RS16175
gene id: 458817:SHAL_RS16175
uniprot id: B0TQ90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

458817:SHAL RS12805
gene id: 458817:SHAL_RS12805
uniprot id: B0TJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

458817:SHAL RS20775
gene id: 458817:SHAL_RS20775
uniprot id: B0TKH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

458817:SHAL RS09750
gene id: 458817:SHAL_RS09750
uniprot id: B0TRM8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

458817:SHAL RS21580
gene id: 458817:SHAL_RS21580
uniprot id: B0TMW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

458817:SHAL RS10885
gene id: 458817:SHAL_RS10885
uniprot id: B0TTS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS19045
gene id: 458817:SHAL_RS19045
uniprot id: B0TUV6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

458817:SHAL RS13485
gene id: 458817:SHAL_RS13485
uniprot id: B0TKD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

458817:SHAL RS10050
gene id: 458817:SHAL_RS10050
uniprot id: B0TSB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

458817:SHAL RS10165
gene id: 458817:SHAL_RS10165
uniprot id: B0TSD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

458817:SHAL RS05890
gene id: 458817:SHAL_RS05890
uniprot id: B0TJD3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

458817:SHAL RS14160
gene id: 458817:SHAL_RS14160
uniprot id: B0TLR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

458817:SHAL RS17175
gene id: 458817:SHAL_RS17175
uniprot id: B0TRU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

458817:SHAL RS16535
gene id: 458817:SHAL_RS16535
uniprot id: B0TR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

458817:SHAL RS06005
gene id: 458817:SHAL_RS06005
uniprot id: B0TJW0
names: Similarity
messages: Belongs to the SUI1 family.

458817:SHAL RS07650
gene id: 458817:SHAL_RS07650
uniprot id: B0TMI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

458817:SHAL RS21045
gene id: 458817:SHAL_RS21045
uniprot id: B0TL69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

458817:SHAL RS07885
gene id: 458817:SHAL_RS07885
uniprot id: B0TNB5
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

458817:SHAL RS14780
gene id: 458817:SHAL_RS14780
uniprot id: B0TMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

458817:SHAL RS06255
gene id: 458817:SHAL_RS06255
uniprot id: B0TK08
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

458817:SHAL RS06290
gene id: 458817:SHAL_RS06290
uniprot id: B0TK15
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

458817:SHAL RS08080
gene id: 458817:SHAL_RS08080
uniprot id: B0TND5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

458817:SHAL RS20860
gene id: 458817:SHAL_RS20860
uniprot id: B0TKJ4
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

458817:SHAL RS04695
gene id: 458817:SHAL_RS04695
uniprot id: B0TV58
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

458817:SHAL RS16985
gene id: 458817:SHAL_RS16985
uniprot id: B0TRR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS21625
gene id: 458817:SHAL_RS21625
uniprot id: B0TMX7
names: Similarity
messages: Belongs to the GSP C family.

458817:SHAL RS18775
gene id: 458817:SHAL_RS18775
uniprot id: B0TU63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

458817:SHAL RS08760
gene id: 458817:SHAL_RS08760
uniprot id: B0TPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

458817:SHAL RS05545
gene id: 458817:SHAL_RS05545
uniprot id: B0TJ70
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

458817:SHAL RS01975
gene id: 458817:SHAL_RS01975
uniprot id: B0TPU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

458817:SHAL RS15930
gene id: 458817:SHAL_RS15930
uniprot id: B0TQ39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

458817:SHAL RS02800
gene id: 458817:SHAL_RS02800
uniprot id: B0TRF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multiheme cytochrome c family.
messages: Binds 8 heme c groups covalently per monomer.
messages: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
messages: Periplasm
messages: Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.

458817:SHAL RS04845
gene id: 458817:SHAL_RS04845
uniprot id: B0TV86
names: Similarity
messages: Belongs to the MEMO1 family.

458817:SHAL RS20140
gene id: 458817:SHAL_RS20140
uniprot id: B0TJ35
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

458817:SHAL RS00395
gene id: 458817:SHAL_RS00395
uniprot id: B0TM60
names: Similarity
messages: Belongs to the RutC family.

458817:SHAL RS14815
gene id: 458817:SHAL_RS14815
uniprot id: B0TMQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS11060
gene id: 458817:SHAL_RS11060
uniprot id: B0TTV8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

458817:SHAL RS12425
gene id: 458817:SHAL_RS12425
uniprot id: B0TJ04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

458817:SHAL RS07055
gene id: 458817:SHAL_RS07055
uniprot id: B0TLI8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

458817:SHAL RS01505
gene id: 458817:SHAL_RS01505
uniprot id: B0TNX2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

458817:SHAL RS10910
gene id: 458817:SHAL_RS10910
uniprot id: B0TTS9
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

458817:SHAL RS12560
gene id: 458817:SHAL_RS12560
uniprot id: B0TJH2
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

458817:SHAL RS05465
gene id: 458817:SHAL_RS05465
uniprot id: B0TIV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

458817:SHAL RS15395
gene id: 458817:SHAL_RS15395
uniprot id: B0TP80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

458817:SHAL RS08325
gene id: 458817:SHAL_RS08325
uniprot id: B0TP14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

458817:SHAL RS19295
gene id: 458817:SHAL_RS19295
uniprot id: B0TV07
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

458817:SHAL RS15910
gene id: 458817:SHAL_RS15910
uniprot id: B0TQ35
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

458817:SHAL RS03345
gene id: 458817:SHAL_RS03345
uniprot id: B0TSQ4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

458817:SHAL RS21345
gene id: 458817:SHAL_RS21345
uniprot id: B0TM06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

458817:SHAL RS20855
gene id: 458817:SHAL_RS20855
uniprot id: B0TKJ3
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

458817:SHAL RS14880
gene id: 458817:SHAL_RS14880
uniprot id: B0TMR4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

458817:SHAL RS09545
gene id: 458817:SHAL_RS09545
uniprot id: B0TRJ0
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS03870
gene id: 458817:SHAL_RS03870
uniprot id: B0TTI7
names: Similarity
messages: Belongs to the SfsA family.

458817:SHAL RS03325
gene id: 458817:SHAL_RS03325
uniprot id: B0TSQ0
names: Similarity
messages: Belongs to the RutC family.

458817:SHAL RS01750
gene id: 458817:SHAL_RS01750
uniprot id: B0TPQ1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

458817:SHAL RS12640
gene id: 458817:SHAL_RS12640
uniprot id: B0TJI9
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

458817:SHAL RS19780
gene id: 458817:SHAL_RS19780
uniprot id: B0TVR8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

458817:SHAL RS03505
gene id: 458817:SHAL_RS03505
uniprot id: B0TST4
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS10650
gene id: 458817:SHAL_RS10650
uniprot id: B0TT39
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

458817:SHAL RS08610
gene id: 458817:SHAL_RS08610
uniprot id: B0TPV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

458817:SHAL RS14570
gene id: 458817:SHAL_RS14570
uniprot id: B0TMK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

458817:SHAL RS02385
gene id: 458817:SHAL_RS02385
uniprot id: B0TQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

458817:SHAL RS19550
gene id: 458817:SHAL_RS19550
uniprot id: B0TVL9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

458817:SHAL RS08570
gene id: 458817:SHAL_RS08570
uniprot id: B0TP64
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

458817:SHAL RS21595
gene id: 458817:SHAL_RS21595
uniprot id: B0TMX1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

458817:SHAL RS18325
gene id: 458817:SHAL_RS18325
uniprot id: B0TTE5
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

458817:SHAL RS10005
gene id: 458817:SHAL_RS10005
uniprot id: B0TSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

458817:SHAL RS14345
gene id: 458817:SHAL_RS14345
uniprot id: B0TLU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

458817:SHAL RS09790
gene id: 458817:SHAL_RS09790
uniprot id: B0TRN5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

458817:SHAL RS04090
gene id: 458817:SHAL_RS04090
uniprot id: B0TTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

458817:SHAL RS17055
gene id: 458817:SHAL_RS17055
uniprot id: B0TRS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

458817:SHAL RS16670
gene id: 458817:SHAL_RS16670
uniprot id: B0TR39
names: Similarity
messages: Belongs to the PhoH family.

458817:SHAL RS00075
gene id: 458817:SHAL_RS00075
uniprot id: B0TLB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

458817:SHAL RS12940
gene id: 458817:SHAL_RS12940
uniprot id: B0TJP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

458817:SHAL RS03205
gene id: 458817:SHAL_RS03205
uniprot id: B0TS65
names: Similarity
messages: Belongs to the Gfa family.

458817:SHAL RS18490
gene id: 458817:SHAL_RS18490
uniprot id: B0TU07
names: Similarity
messages: Belongs to the PspA/IM30 family.

458817:SHAL RS13230
gene id: 458817:SHAL_RS13230
uniprot id: B0TK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

458817:SHAL RS16270
gene id: 458817:SHAL_RS16270
uniprot id: B0TQA7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

458817:SHAL RS21915
gene id: 458817:SHAL_RS21915
uniprot id: B0TPH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

458817:SHAL RS01885
gene id: 458817:SHAL_RS01885
uniprot id: B0TPS7
names: Subunit
messages: Monomer.

458817:SHAL RS12140
gene id: 458817:SHAL_RS12140
uniprot id: B0TVK3
names: Similarity
messages: Belongs to the ArsC family.

458817:SHAL RS01570
gene id: 458817:SHAL_RS01570
uniprot id: B0TPL7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

458817:SHAL RS17420
gene id: 458817:SHAL_RS17420
uniprot id: B0TRZ6
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS00545
gene id: 458817:SHAL_RS00545
uniprot id: B0TM90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

458817:SHAL RS07405
gene id: 458817:SHAL_RS07405
uniprot id: B0TMD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

458817:SHAL RS12890
gene id: 458817:SHAL_RS12890
uniprot id: B0TJN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

458817:SHAL RS10000
gene id: 458817:SHAL_RS10000
uniprot id: B0TSB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

458817:SHAL RS13050
gene id: 458817:SHAL_RS13050
uniprot id: B0TK48
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

458817:SHAL RS09190
gene id: 458817:SHAL_RS09190
uniprot id: B0TQU2
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

458817:SHAL RS04875
gene id: 458817:SHAL_RS04875
uniprot id: B0TV92
names: Similarity
messages: Belongs to the DEAD box helicase family.

458817:SHAL RS00650
gene id: 458817:SHAL_RS00650
uniprot id: B0TMB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

458817:SHAL RS16180
gene id: 458817:SHAL_RS16180
uniprot id: B0TQ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

458817:SHAL RS21160
gene id: 458817:SHAL_RS21160
uniprot id: B0TL92
names: Similarity
messages: Belongs to the CinA family.

458817:SHAL RS13850
gene id: 458817:SHAL_RS13850
uniprot id: B0TL22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

458817:SHAL RS02260
gene id: 458817:SHAL_RS02260
uniprot id: B0TQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

458817:SHAL RS04230
gene id: 458817:SHAL_RS04230
uniprot id: B0TUA2
names: Subcellular Location Annotation
messages: Membrane

458817:SHAL RS02280
gene id: 458817:SHAL_RS02280
uniprot id: B0TQN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

458817:SHAL RS13790
gene id: 458817:SHAL_RS13790
uniprot id: B0TL08
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

458817:SHAL RS01075
gene id: 458817:SHAL_RS01075
uniprot id: B0TN77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

458817:SHAL RS05715
gene id: 458817:SHAL_RS05715
uniprot id: B0TJA4
names: Similarity
messages: Belongs to the UPF0246 family.