456481:LEPBI RS07590
gene id: 456481:LEPBI_RS07590
uniprot id: B0SQJ1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

456481:LEPBI RS01140
gene id: 456481:LEPBI_RS01140
uniprot id: B0SKG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS10530
gene id: 456481:LEPBI_RS10530
uniprot id: B0SSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

456481:LEPBI RS05450
gene id: 456481:LEPBI_RS05450
uniprot id: B0SN44
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS02495
gene id: 456481:LEPBI_RS02495
uniprot id: B0SJ52
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

456481:LEPBI RS08585
gene id: 456481:LEPBI_RS08585
uniprot id: B0SRP9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

456481:LEPBI RS12750
gene id: 456481:LEPBI_RS12750
uniprot id: B0SM41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

456481:LEPBI RS06820
gene id: 456481:LEPBI_RS06820
uniprot id: B0SPT4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

456481:LEPBI RS08215
gene id: 456481:LEPBI_RS08215
uniprot id: B0SR69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

456481:LEPBI RS09185
gene id: 456481:LEPBI_RS09185
uniprot id: B0SS74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

456481:LEPBI RS12755
gene id: 456481:LEPBI_RS12755
uniprot id: B0SM42
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

456481:LEPBI RS04660
gene id: 456481:LEPBI_RS04660
uniprot id: B0SMD0
names: Similarity
messages: Belongs to the RemA family.

456481:LEPBI RS17330
gene id: 456481:LEPBI_RS17330
uniprot id: B0STQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

456481:LEPBI RS03945
gene id: 456481:LEPBI_RS03945
uniprot id: B0SLC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

456481:LEPBI RS12870
gene id: 456481:LEPBI_RS12870
uniprot id: B0SM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

456481:LEPBI RS09625
gene id: 456481:LEPBI_RS09625
uniprot id: B0SSG1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

456481:LEPBI RS09690
gene id: 456481:LEPBI_RS09690
uniprot id: B0SSH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

456481:LEPBI RS08665
gene id: 456481:LEPBI_RS08665
uniprot id: B0SRR5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

456481:LEPBI RS06945
gene id: 456481:LEPBI_RS06945
uniprot id: B0SPV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

456481:LEPBI RS16670
gene id: 456481:LEPBI_RS16670
uniprot id: B0SRH3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

456481:LEPBI RS17550
gene id: 456481:LEPBI_RS17550
uniprot id: B0STU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

456481:LEPBI RS04430
gene id: 456481:LEPBI_RS04430
uniprot id: B0SLX6
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS15235
gene id: 456481:LEPBI_RS15235
uniprot id: B0SQ26
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

456481:LEPBI RS02020
gene id: 456481:LEPBI_RS02020
uniprot id: B0SIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

456481:LEPBI RS07720
gene id: 456481:LEPBI_RS07720
uniprot id: B0SQL5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

456481:LEPBI RS05005
gene id: 456481:LEPBI_RS05005
uniprot id: B0SMJ8
names: Similarity
messages: Belongs to the LOG family.

456481:LEPBI RS09490
gene id: 456481:LEPBI_RS09490
uniprot id: B0SSD5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

456481:LEPBI RS07395
gene id: 456481:LEPBI_RS07395
uniprot id: B0SQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

456481:LEPBI RS08130
gene id: 456481:LEPBI_RS08130
uniprot id: B0SR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

456481:LEPBI RS17890
gene id: 456481:LEPBI_RS17890
uniprot id: B0SU18
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

456481:LEPBI RS07905
gene id: 456481:LEPBI_RS07905
uniprot id: B0SR08
names: Similarity
messages: Belongs to the band 7/mec-2 family.

456481:LEPBI RS04015
gene id: 456481:LEPBI_RS04015
uniprot id: B0SLP4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

456481:LEPBI RS06720
gene id: 456481:LEPBI_RS06720
uniprot id: B0SPR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

456481:LEPBI RS14415
gene id: 456481:LEPBI_RS14415
uniprot id: B0SNZ7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

456481:LEPBI RS12770
gene id: 456481:LEPBI_RS12770
uniprot id: B0SM45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

456481:LEPBI RS02970
gene id: 456481:LEPBI_RS02970
uniprot id: B0SKI3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

456481:LEPBI RS09620
gene id: 456481:LEPBI_RS09620
uniprot id: B0SSG0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

456481:LEPBI RS10290
gene id: 456481:LEPBI_RS10290
uniprot id: B0SSU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

456481:LEPBI RS09715
gene id: 456481:LEPBI_RS09715
uniprot id: B0SSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

456481:LEPBI RS18390
gene id: 456481:LEPBI_RS18390
uniprot id: B0SUC2
names: Similarity
messages: Belongs to the pyruvate kinase family.

456481:LEPBI RS08440
gene id: 456481:LEPBI_RS08440
uniprot id: B0SRL9
names: Similarity
messages: Belongs to the peptidase U62 family.

456481:LEPBI RS01510
gene id: 456481:LEPBI_RS01510
uniprot id: B0SJD4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

456481:LEPBI RS05875
gene id: 456481:LEPBI_RS05875
uniprot id: B0SNN2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS06440
gene id: 456481:LEPBI_RS06440
uniprot id: B0SPA1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

456481:LEPBI RS01715
gene id: 456481:LEPBI_RS01715
uniprot id: B0SKE9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

456481:LEPBI RS00525
gene id: 456481:LEPBI_RS00525
uniprot id: B0SJT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS02635
gene id: 456481:LEPBI_RS02635
uniprot id: B0SJF5
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS17530
gene id: 456481:LEPBI_RS17530
uniprot id: B0STU5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

456481:LEPBI RS14480
gene id: 456481:LEPBI_RS14480
uniprot id: B0SP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

456481:LEPBI RS03565
gene id: 456481:LEPBI_RS03565
uniprot id: B0SL48
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

456481:LEPBI RS17335
gene id: 456481:LEPBI_RS17335
uniprot id: B0STQ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

456481:LEPBI RS06705
gene id: 456481:LEPBI_RS06705
uniprot id: B0SPR0
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS11600
gene id: 456481:LEPBI_RS11600
uniprot id: B0SKU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

456481:LEPBI RS12725
gene id: 456481:LEPBI_RS12725
uniprot id: B0SM36
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

456481:LEPBI RS04590
gene id: 456481:LEPBI_RS04590
uniprot id: B0SMB6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

456481:LEPBI RS11790
gene id: 456481:LEPBI_RS11790
uniprot id: B0SKY4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

456481:LEPBI RS12560
gene id: 456481:LEPBI_RS12560
uniprot id: B0SM03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

456481:LEPBI RS14475
gene id: 456481:LEPBI_RS14475
uniprot id: B0SP09
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

456481:LEPBI RS02190
gene id: 456481:LEPBI_RS02190
uniprot id: B0SJN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

456481:LEPBI RS17250
gene id: 456481:LEPBI_RS17250
uniprot id: B0STP0
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

456481:LEPBI RS16680
gene id: 456481:LEPBI_RS16680
uniprot id: B0SRH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

456481:LEPBI RS02470
gene id: 456481:LEPBI_RS02470
uniprot id: B0SJ47
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS13185
gene id: 456481:LEPBI_RS13185
uniprot id: B0SMN5
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS09505
gene id: 456481:LEPBI_RS09505
uniprot id: B0SSD8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

456481:LEPBI RS11305
gene id: 456481:LEPBI_RS11305
uniprot id: B0STE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

456481:LEPBI RS14715
gene id: 456481:LEPBI_RS14715
uniprot id: B0SPG6
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

456481:LEPBI RS16165
gene id: 456481:LEPBI_RS16165
uniprot id: B0SQW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

456481:LEPBI RS05880
gene id: 456481:LEPBI_RS05880
uniprot id: B0SNN3
names: Similarity
messages: Belongs to the TrpC family.

456481:LEPBI RS15865
gene id: 456481:LEPBI_RS15865
uniprot id: B0SQQ7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

456481:LEPBI RS01065
gene id: 456481:LEPBI_RS01065
uniprot id: B0SKC1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

456481:LEPBI RS09655
gene id: 456481:LEPBI_RS09655
uniprot id: B0SSG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

456481:LEPBI RS03615
gene id: 456481:LEPBI_RS03615
uniprot id: B0SL58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

456481:LEPBI RS03610
gene id: 456481:LEPBI_RS03610
uniprot id: B0SL57
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS03330
gene id: 456481:LEPBI_RS03330
uniprot id: B0SKQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS00735
gene id: 456481:LEPBI_RS00735
uniprot id: B0SJY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

456481:LEPBI RS01365
gene id: 456481:LEPBI_RS01365
uniprot id: B0SJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS10355
gene id: 456481:LEPBI_RS10355
uniprot id: B0SSV8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

456481:LEPBI RS14790
gene id: 456481:LEPBI_RS14790
uniprot id: B0SPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

456481:LEPBI RS02085
gene id: 456481:LEPBI_RS02085
uniprot id: B0SK17
names: Similarity
messages: Belongs to the AHA1 family.

456481:LEPBI RS15080
gene id: 456481:LEPBI_RS15080
uniprot id: B0SPP0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS04545
gene id: 456481:LEPBI_RS04545
uniprot id: B0SMA7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

456481:LEPBI RS17745
gene id: 456481:LEPBI_RS17745
uniprot id: B0STY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

456481:LEPBI RS03640
gene id: 456481:LEPBI_RS03640
uniprot id: B0SL63
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

456481:LEPBI RS14575
gene id: 456481:LEPBI_RS14575
uniprot id: B0SP31
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS17940
gene id: 456481:LEPBI_RS17940
uniprot id: B0SU28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS09300
gene id: 456481:LEPBI_RS09300
uniprot id: B0SS97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

456481:LEPBI RS03425
gene id: 456481:LEPBI_RS03425
uniprot id: B0SKS1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

456481:LEPBI RS16565
gene id: 456481:LEPBI_RS16565
uniprot id: B0SRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

456481:LEPBI RS09965
gene id: 456481:LEPBI_RS09965
uniprot id: B0SSN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS03845
gene id: 456481:LEPBI_RS03845
uniprot id: B0SLA4
names: Similarity
messages: Belongs to the histone deacetylase family.

456481:LEPBI RS01805
gene id: 456481:LEPBI_RS01805
uniprot id: B0SIY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

456481:LEPBI RS08690
gene id: 456481:LEPBI_RS08690
uniprot id: B0SRS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

456481:LEPBI RS10330
gene id: 456481:LEPBI_RS10330
uniprot id: B0SSV3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

456481:LEPBI RS11570
gene id: 456481:LEPBI_RS11570
uniprot id: B0SKU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

456481:LEPBI RS00425
gene id: 456481:LEPBI_RS00425
uniprot id: B0SJT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

456481:LEPBI RS12990
gene id: 456481:LEPBI_RS12990
uniprot id: B0SM90
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS12585
gene id: 456481:LEPBI_RS12585
uniprot id: B0SM08
names: Similarity
messages: Belongs to the ArsC family.

456481:LEPBI RS08045
gene id: 456481:LEPBI_RS08045
uniprot id: B0SR35
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS08520
gene id: 456481:LEPBI_RS08520
uniprot id: B0SRN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS09315
gene id: 456481:LEPBI_RS09315
uniprot id: B0SSA0
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS18435
gene id: 456481:LEPBI_RS18435
uniprot id: B0SUD2
names: Similarity
messages: Belongs to the ParB family.

456481:LEPBI RS04080
gene id: 456481:LEPBI_RS04080
uniprot id: B0SLQ7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

456481:LEPBI RS00025
gene id: 456481:LEPBI_RS00025
uniprot id: B0SK32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

456481:LEPBI RS18710
gene id: 456481:LEPBI_RS18710
uniprot id: B0SUI7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

456481:LEPBI RS15905
gene id: 456481:LEPBI_RS15905
uniprot id: B0SQR5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

456481:LEPBI RS18095
gene id: 456481:LEPBI_RS18095
uniprot id: B0SU59
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS15375
gene id: 456481:LEPBI_RS15375
uniprot id: B0SQ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

456481:LEPBI RS06400
gene id: 456481:LEPBI_RS06400
uniprot id: B0SP93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

456481:LEPBI RS03730
gene id: 456481:LEPBI_RS03730
uniprot id: B0SL81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

456481:LEPBI RS08280
gene id: 456481:LEPBI_RS08280
uniprot id: B0SR82
names: Similarity
messages: Belongs to the GSP E family.

456481:LEPBI RS13055
gene id: 456481:LEPBI_RS13055
uniprot id: B0SMA3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

456481:LEPBI RS11575
gene id: 456481:LEPBI_RS11575
uniprot id: B0SKU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

456481:LEPBI RS10585
gene id: 456481:LEPBI_RS10585
uniprot id: B0ST06
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

456481:LEPBI RS12275
gene id: 456481:LEPBI_RS12275
uniprot id: B0SLJ0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

456481:LEPBI RS12515
gene id: 456481:LEPBI_RS12515
uniprot id: B0SLN8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

456481:LEPBI RS05740
gene id: 456481:LEPBI_RS05740
uniprot id: B0SNK5
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

456481:LEPBI RS07525
gene id: 456481:LEPBI_RS07525
uniprot id: B0SQH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

456481:LEPBI RS18185
gene id: 456481:LEPBI_RS18185
uniprot id: B0SU80
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS18275
gene id: 456481:LEPBI_RS18275
uniprot id: B0SU98
names: Subcellular Location Annotation
messages: Mitochondrion

456481:LEPBI RS14640
gene id: 456481:LEPBI_RS14640
uniprot id: B0SPF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

456481:LEPBI RS13955
gene id: 456481:LEPBI_RS13955
uniprot id: B0SNF2
names: Similarity
messages: Belongs to the Fur family.

456481:LEPBI RS10510
gene id: 456481:LEPBI_RS10510
uniprot id: B0SSZ0
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

456481:LEPBI RS00965
gene id: 456481:LEPBI_RS00965
uniprot id: B0SK94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

456481:LEPBI RS06665
gene id: 456481:LEPBI_RS06665
uniprot id: B0SPE4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

456481:LEPBI RS06780
gene id: 456481:LEPBI_RS06780
uniprot id: B0SPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

456481:LEPBI RS17980
gene id: 456481:LEPBI_RS17980
uniprot id: B0SU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

456481:LEPBI RS17040
gene id: 456481:LEPBI_RS17040
uniprot id: B0SRZ7
names: Similarity
messages: Belongs to the ParB family.

456481:LEPBI RS10360
gene id: 456481:LEPBI_RS10360
uniprot id: B0SSV9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

456481:LEPBI RS03705
gene id: 456481:LEPBI_RS03705
uniprot id: B0SL76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

456481:LEPBI RS07960
gene id: 456481:LEPBI_RS07960
uniprot id: B0SR19
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: The homodimer mediates transmembrane sugar transport down a concentration gradient. Transport is probably effected by rocking-type movements, where a cargo-binding cavity opens first on one and then on the other side of the membrane.

456481:LEPBI RS09870
gene id: 456481:LEPBI_RS09870
uniprot id: B0SSL0
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

456481:LEPBI RS12840
gene id: 456481:LEPBI_RS12840
uniprot id: B0SM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

456481:LEPBI RS08185
gene id: 456481:LEPBI_RS08185
uniprot id: B0SR63
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

456481:LEPBI RS06405
gene id: 456481:LEPBI_RS06405
uniprot id: B0SP94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

456481:LEPBI RS09430
gene id: 456481:LEPBI_RS09430
uniprot id: B0SSC3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

456481:LEPBI RS07700
gene id: 456481:LEPBI_RS07700
uniprot id: B0SQL1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

456481:LEPBI RS18370
gene id: 456481:LEPBI_RS18370
uniprot id: B0SUB8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

456481:LEPBI RS03955
gene id: 456481:LEPBI_RS03955
uniprot id: B0SLC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

456481:LEPBI RS01885
gene id: 456481:LEPBI_RS01885
uniprot id: B0SIZ4
names: Similarity
messages: Belongs to the hemerythrin family.

456481:LEPBI RS03485
gene id: 456481:LEPBI_RS03485
uniprot id: B0SL32
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

456481:LEPBI RS17930
gene id: 456481:LEPBI_RS17930
uniprot id: B0SU26
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

456481:LEPBI RS16075
gene id: 456481:LEPBI_RS16075
uniprot id: B0SQV0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

456481:LEPBI RS07805
gene id: 456481:LEPBI_RS07805
uniprot id: B0SQY8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

456481:LEPBI RS07840
gene id: 456481:LEPBI_RS07840
uniprot id: B0SQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

456481:LEPBI RS08155
gene id: 456481:LEPBI_RS08155
uniprot id: B0SR57
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

456481:LEPBI RS14600
gene id: 456481:LEPBI_RS14600
uniprot id: B0SP36
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS00575
gene id: 456481:LEPBI_RS00575
uniprot id: B0SJU4
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS08410
gene id: 456481:LEPBI_RS08410
uniprot id: B0SRL3
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

456481:LEPBI RS02555
gene id: 456481:LEPBI_RS02555
uniprot id: B0SJ59
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS02075
gene id: 456481:LEPBI_RS02075
uniprot id: B0SK14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

456481:LEPBI RS15935
gene id: 456481:LEPBI_RS15935
uniprot id: B0SQS2
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS09555
gene id: 456481:LEPBI_RS09555
uniprot id: B0SSE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

456481:LEPBI RS00520
gene id: 456481:LEPBI_RS00520
uniprot id: B0SJT7
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS08070
gene id: 456481:LEPBI_RS08070
uniprot id: B0SR40
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

456481:LEPBI RS17205
gene id: 456481:LEPBI_RS17205
uniprot id: B0STN0
names: Similarity
messages: Belongs to the ParB family.

456481:LEPBI RS17065
gene id: 456481:LEPBI_RS17065
uniprot id: B0SS02
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

456481:LEPBI RS10280
gene id: 456481:LEPBI_RS10280
uniprot id: B0SSU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS11725
gene id: 456481:LEPBI_RS11725
uniprot id: B0SKX2
names: Similarity
messages: Belongs to the phosphopentomutase family.

456481:LEPBI RS06775
gene id: 456481:LEPBI_RS06775
uniprot id: B0SPS5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

456481:LEPBI RS10320
gene id: 456481:LEPBI_RS10320
uniprot id: B0SSV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS09230
gene id: 456481:LEPBI_RS09230
uniprot id: B0SS83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

456481:LEPBI RS04980
gene id: 456481:LEPBI_RS04980
uniprot id: B0SMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS06055
gene id: 456481:LEPBI_RS06055
uniprot id: B0SNR9
names: Similarity
messages: Belongs to the YciI family.

456481:LEPBI RS05435
gene id: 456481:LEPBI_RS05435
uniprot id: B0SN41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

456481:LEPBI RS07495
gene id: 456481:LEPBI_RS07495
uniprot id: B0SQH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

456481:LEPBI RS08180
gene id: 456481:LEPBI_RS08180
uniprot id: B0SR62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS17475
gene id: 456481:LEPBI_RS17475
uniprot id: B0STT4
names: Similarity
messages: Belongs to the UDPGP type 1 family.

456481:LEPBI RS14490
gene id: 456481:LEPBI_RS14490
uniprot id: B0SP14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS12825
gene id: 456481:LEPBI_RS12825
uniprot id: Q5MI53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

456481:LEPBI RS01705
gene id: 456481:LEPBI_RS01705
uniprot id: B0SKE3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

456481:LEPBI RS08720
gene id: 456481:LEPBI_RS08720
uniprot id: B0SRS6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

456481:LEPBI RS02810
gene id: 456481:LEPBI_RS02810
uniprot id: B0SJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

456481:LEPBI RS08160
gene id: 456481:LEPBI_RS08160
uniprot id: B0SR58
names: Subcellular Location Annotation
messages: Cytoplasm

456481:LEPBI RS06425
gene id: 456481:LEPBI_RS06425
uniprot id: B0SP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

456481:LEPBI RS10620
gene id: 456481:LEPBI_RS10620
uniprot id: B0ST14
names: Similarity
messages: Belongs to the Fur family.

456481:LEPBI RS04805
gene id: 456481:LEPBI_RS04805
uniprot id: B0SMF8
names: Similarity
messages: Belongs to the SCO1/2 family.

456481:LEPBI RS07535
gene id: 456481:LEPBI_RS07535
uniprot id: B0SQI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

456481:LEPBI RS15880
gene id: 456481:LEPBI_RS15880
uniprot id: B0SQR0
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

456481:LEPBI RS02370
gene id: 456481:LEPBI_RS02370
uniprot id: B0SJ72
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

456481:LEPBI RS04055
gene id: 456481:LEPBI_RS04055
uniprot id: B0SLQ2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

456481:LEPBI RS04985
gene id: 456481:LEPBI_RS04985
uniprot id: B0SMJ4
names: Similarity
messages: Belongs to the peptidase S49 family.

456481:LEPBI RS09640
gene id: 456481:LEPBI_RS09640
uniprot id: B0SSG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

456481:LEPBI RS09200
gene id: 456481:LEPBI_RS09200
uniprot id: B0SS77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

456481:LEPBI RS16560
gene id: 456481:LEPBI_RS16560
uniprot id: B0SRF1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

456481:LEPBI RS03935
gene id: 456481:LEPBI_RS03935
uniprot id: B0SLC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

456481:LEPBI RS06260
gene id: 456481:LEPBI_RS06260
uniprot id: B0SP65
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

456481:LEPBI RS18675
gene id: 456481:LEPBI_RS18675
uniprot id: B0SUI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS11955
gene id: 456481:LEPBI_RS11955
uniprot id: B0SL18
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS05465
gene id: 456481:LEPBI_RS05465
uniprot id: B0SN47
names: Similarity
messages: Belongs to the UPF0473 family.

456481:LEPBI RS10105
gene id: 456481:LEPBI_RS10105
uniprot id: B0SSQ8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

456481:LEPBI RS07680
gene id: 456481:LEPBI_RS07680
uniprot id: B0SQK7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

456481:LEPBI RS03620
gene id: 456481:LEPBI_RS03620
uniprot id: B0SL59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

456481:LEPBI RS00970
gene id: 456481:LEPBI_RS00970
uniprot id: B0SK95
names: Similarity
messages: Belongs to the MotB family.

456481:LEPBI RS15115
gene id: 456481:LEPBI_RS15115
uniprot id: B0SPP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

456481:LEPBI RS14210
gene id: 456481:LEPBI_RS14210
uniprot id: B0SNV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

456481:LEPBI RS14695
gene id: 456481:LEPBI_RS14695
uniprot id: B0SPG2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

456481:LEPBI RS01450
gene id: 456481:LEPBI_RS01450
uniprot id: B0SJ18
names: Similarity
messages: Belongs to the GST superfamily.

456481:LEPBI RS09190
gene id: 456481:LEPBI_RS09190
uniprot id: B0SS75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

456481:LEPBI RS02320
gene id: 456481:LEPBI_RS02320
uniprot id: B0SJ44
names: Similarity
messages: Belongs to the peptidase S41A family.

456481:LEPBI RS00045
gene id: 456481:LEPBI_RS00045
uniprot id: B0SK36
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

456481:LEPBI RS00750
gene id: 456481:LEPBI_RS00750
uniprot id: B0SJZ1
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS03940
gene id: 456481:LEPBI_RS03940
uniprot id: B0SLC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

456481:LEPBI RS17120
gene id: 456481:LEPBI_RS17120
uniprot id: B0STL3
names: Similarity
messages: Belongs to the heat shock protein 90 family.

456481:LEPBI RS17435
gene id: 456481:LEPBI_RS17435
uniprot id: B0STS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS13190
gene id: 456481:LEPBI_RS13190
uniprot id: B0SMN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS00320
gene id: 456481:LEPBI_RS00320
uniprot id: B0SJP7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS02825
gene id: 456481:LEPBI_RS02825
uniprot id: B0SJA1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

456481:LEPBI RS16385
gene id: 456481:LEPBI_RS16385
uniprot id: B0SRB6
names: Similarity
messages: Belongs to the AHA1 family.

456481:LEPBI RS00730
gene id: 456481:LEPBI_RS00730
uniprot id: B0SJY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

456481:LEPBI RS12300
gene id: 456481:LEPBI_RS12300
uniprot id: B0SLJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

456481:LEPBI RS14785
gene id: 456481:LEPBI_RS14785
uniprot id: B0SPI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

456481:LEPBI RS13255
gene id: 456481:LEPBI_RS13255
uniprot id: B0SMP9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

456481:LEPBI RS01735
gene id: 456481:LEPBI_RS01735
uniprot id: B0SKD3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

456481:LEPBI RS00280
gene id: 456481:LEPBI_RS00280
uniprot id: B0SJN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

456481:LEPBI RS09770
gene id: 456481:LEPBI_RS09770
uniprot id: B0SSJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

456481:LEPBI RS16420
gene id: 456481:LEPBI_RS16420
uniprot id: B0SRC3
names: Similarity
messages: Belongs to the pirin family.

456481:LEPBI RS05195
gene id: 456481:LEPBI_RS05195
uniprot id: B0SMZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

456481:LEPBI RS17185
gene id: 456481:LEPBI_RS17185
uniprot id: B0STM6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

456481:LEPBI RS14825
gene id: 456481:LEPBI_RS14825
uniprot id: B0SPI8
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS03240
gene id: 456481:LEPBI_RS03240
uniprot id: B0SKN4
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS09660
gene id: 456481:LEPBI_RS09660
uniprot id: B0SSG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

456481:LEPBI RS07755
gene id: 456481:LEPBI_RS07755
uniprot id: B0SQM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

456481:LEPBI RS17410
gene id: 456481:LEPBI_RS17410
uniprot id: B0STS1
names: Similarity
messages: Belongs to the glutamate synthase family.

456481:LEPBI RS07385
gene id: 456481:LEPBI_RS07385
uniprot id: B0SQF2
names: Similarity
messages: Belongs to the peptidase C40 family.

456481:LEPBI RS16895
gene id: 456481:LEPBI_RS16895
uniprot id: B0SRX3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

456481:LEPBI RS09760
gene id: 456481:LEPBI_RS09760
uniprot id: B0SSI8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

456481:LEPBI RS07540
gene id: 456481:LEPBI_RS07540
uniprot id: B0SQI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

456481:LEPBI RS09745
gene id: 456481:LEPBI_RS09745
uniprot id: B0SSI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

456481:LEPBI RS08535
gene id: 456481:LEPBI_RS08535
uniprot id: B0SRN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

456481:LEPBI RS00890
gene id: 456481:LEPBI_RS00890
uniprot id: B0SK90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

456481:LEPBI RS03440
gene id: 456481:LEPBI_RS03440
uniprot id: B0SKS4
names: Similarity
messages: Belongs to the CutA family.

456481:LEPBI RS08330
gene id: 456481:LEPBI_RS08330
uniprot id: B0SRJ8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

456481:LEPBI RS16025
gene id: 456481:LEPBI_RS16025
uniprot id: B0SQU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS09465
gene id: 456481:LEPBI_RS09465
uniprot id: B0SSD0
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

456481:LEPBI RS14780
gene id: 456481:LEPBI_RS14780
uniprot id: B0SPH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

456481:LEPBI RS11660
gene id: 456481:LEPBI_RS11660
uniprot id: B0SKV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

456481:LEPBI RS14165
gene id: 456481:LEPBI_RS14165
uniprot id: B0SNU8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

456481:LEPBI RS12940
gene id: 456481:LEPBI_RS12940
uniprot id: B0SM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS04585
gene id: 456481:LEPBI_RS04585
uniprot id: B0SMB5
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS17850
gene id: 456481:LEPBI_RS17850
uniprot id: B0SU09
names: Similarity
messages: Belongs to the photoactive yellow protein family.

456481:LEPBI RS12520
gene id: 456481:LEPBI_RS12520
uniprot id: B0SLN9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

456481:LEPBI RS06800
gene id: 456481:LEPBI_RS06800
uniprot id: B0SPT0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

456481:LEPBI RS03095
gene id: 456481:LEPBI_RS03095
uniprot id: B0SKK7
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

456481:LEPBI RS17490
gene id: 456481:LEPBI_RS17490
uniprot id: B0STT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

456481:LEPBI RS04335
gene id: 456481:LEPBI_RS04335
uniprot id: B0SLV8
names: Similarity
messages: Belongs to the lipase chaperone family.

456481:LEPBI RS16355
gene id: 456481:LEPBI_RS16355
uniprot id: B0SRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

456481:LEPBI RS04765
gene id: 456481:LEPBI_RS04765
uniprot id: B0SMF0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

456481:LEPBI RS06325
gene id: 456481:LEPBI_RS06325
uniprot id: B0SP78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

456481:LEPBI RS01595
gene id: 456481:LEPBI_RS01595
uniprot id: B0SJJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

456481:LEPBI RS10070
gene id: 456481:LEPBI_RS10070
uniprot id: B0SSQ1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

456481:LEPBI RS00375
gene id: 456481:LEPBI_RS00375
uniprot id: B0SJQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

456481:LEPBI RS01540
gene id: 456481:LEPBI_RS01540
uniprot id: B0SJE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

456481:LEPBI RS10385
gene id: 456481:LEPBI_RS10385
uniprot id: B0SSW4
names: Similarity
messages: Belongs to the CapA family.

456481:LEPBI RS13045
gene id: 456481:LEPBI_RS13045
uniprot id: B0SMA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

456481:LEPBI RS03685
gene id: 456481:LEPBI_RS03685
uniprot id: B0SL72
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

456481:LEPBI RS05120
gene id: 456481:LEPBI_RS05120
uniprot id: B0SMX9
names: Similarity
messages: Belongs to the citrate synthase family.

456481:LEPBI RS01345
gene id: 456481:LEPBI_RS01345
uniprot id: B0SJ03
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS14425
gene id: 456481:LEPBI_RS14425
uniprot id: B0SNZ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

456481:LEPBI RS04305
gene id: 456481:LEPBI_RS04305
uniprot id: Q5XPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

456481:LEPBI RS15720
gene id: 456481:LEPBI_RS15720
uniprot id: B0SQM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

456481:LEPBI RS13935
gene id: 456481:LEPBI_RS13935
uniprot id: B0SNE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

456481:LEPBI RS00705
gene id: 456481:LEPBI_RS00705
uniprot id: B0SJV9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

456481:LEPBI RS08055
gene id: 456481:LEPBI_RS08055
uniprot id: B0SR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

456481:LEPBI RS06830
gene id: 456481:LEPBI_RS06830
uniprot id: B0SPT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

456481:LEPBI RS01455
gene id: 456481:LEPBI_RS01455
uniprot id: B0SJE4
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS09240
gene id: 456481:LEPBI_RS09240
uniprot id: B0SS85
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

456481:LEPBI RS16740
gene id: 456481:LEPBI_RS16740
uniprot id: B0SRI7
names: Similarity
messages: Belongs to the peptidase M1 family.

456481:LEPBI RS12830
gene id: 456481:LEPBI_RS12830
uniprot id: B0SM57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

456481:LEPBI RS07375
gene id: 456481:LEPBI_RS07375
uniprot id: B0SQF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

456481:LEPBI RS09750
gene id: 456481:LEPBI_RS09750
uniprot id: B0SSI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

456481:LEPBI RS02185
gene id: 456481:LEPBI_RS02185
uniprot id: B0SJN2
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS10285
gene id: 456481:LEPBI_RS10285
uniprot id: B0SSU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

456481:LEPBI RS12155
gene id: 456481:LEPBI_RS12155
uniprot id: B0SLG6
names: Similarity
messages: Belongs to the ketopantoate reductase family.

456481:LEPBI RS02730
gene id: 456481:LEPBI_RS02730
uniprot id: B0SJD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

456481:LEPBI RS17710
gene id: 456481:LEPBI_RS17710
uniprot id: B0STY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

456481:LEPBI RS12745
gene id: 456481:LEPBI_RS12745
uniprot id: B0SM40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

456481:LEPBI RS11810
gene id: 456481:LEPBI_RS11810
uniprot id: B0SKY8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

456481:LEPBI RS02425
gene id: 456481:LEPBI_RS02425
uniprot id: B0SJ84
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS02170
gene id: 456481:LEPBI_RS02170
uniprot id: B0SJM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS03250
gene id: 456481:LEPBI_RS03250
uniprot id: B0SKN6
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS04040
gene id: 456481:LEPBI_RS04040
uniprot id: B0SLP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

456481:LEPBI RS06925
gene id: 456481:LEPBI_RS06925
uniprot id: B0SPV5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

456481:LEPBI RS05045
gene id: 456481:LEPBI_RS05045
uniprot id: B0SMK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

456481:LEPBI RS05815
gene id: 456481:LEPBI_RS05815
uniprot id: B0SNM1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

456481:LEPBI RS18010
gene id: 456481:LEPBI_RS18010
uniprot id: B0SU42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

456481:LEPBI RS12845
gene id: 456481:LEPBI_RS12845
uniprot id: B0SM60
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

456481:LEPBI RS16555
gene id: 456481:LEPBI_RS16555
uniprot id: B0SRF0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

456481:LEPBI RS04685
gene id: 456481:LEPBI_RS04685
uniprot id: B0SMD5
names: Subcellular Location Annotation
messages: Cytoplasm

456481:LEPBI RS08205
gene id: 456481:LEPBI_RS08205
uniprot id: B0SR67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

456481:LEPBI RS02655
gene id: 456481:LEPBI_RS02655
uniprot id: B0SJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS10065
gene id: 456481:LEPBI_RS10065
uniprot id: B0SSQ0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

456481:LEPBI RS04290
gene id: 456481:LEPBI_RS04290
uniprot id: B0SLU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

456481:LEPBI RS03810
gene id: 456481:LEPBI_RS03810
uniprot id: B0SL97
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

456481:LEPBI RS07860
gene id: 456481:LEPBI_RS07860
uniprot id: B0SQZ9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

456481:LEPBI RS12710
gene id: 456481:LEPBI_RS12710
uniprot id: B0SM33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS00135
gene id: 456481:LEPBI_RS00135
uniprot id: B0SK30
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

456481:LEPBI RS01285
gene id: 456481:LEPBI_RS01285
uniprot id: B0STJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

456481:LEPBI RS14265
gene id: 456481:LEPBI_RS14265
uniprot id: B0SNW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS03770
gene id: 456481:LEPBI_RS03770
uniprot id: B0SL89
names: Similarity
messages: Belongs to the histone deacetylase family.

456481:LEPBI RS08970
gene id: 456481:LEPBI_RS08970
uniprot id: B0SS31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS08575
gene id: 456481:LEPBI_RS08575
uniprot id: B0SRP7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

456481:LEPBI RS15070
gene id: 456481:LEPBI_RS15070
uniprot id: B0SPN8
names: Similarity
messages: Belongs to the ribF family.

456481:LEPBI RS09735
gene id: 456481:LEPBI_RS09735
uniprot id: B0SSI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

456481:LEPBI RS09400
gene id: 456481:LEPBI_RS09400
uniprot id: B0SSB7
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

456481:LEPBI RS16605
gene id: 456481:LEPBI_RS16605
uniprot id: B0SRG0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

456481:LEPBI RS17970
gene id: 456481:LEPBI_RS17970
uniprot id: B0SU34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

456481:LEPBI RS02435
gene id: 456481:LEPBI_RS02435
uniprot id: B0SJ66
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

456481:LEPBI RS01600
gene id: 456481:LEPBI_RS01600
uniprot id: B0SJK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

456481:LEPBI RS01150
gene id: 456481:LEPBI_RS01150
uniprot id: B0SKG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

456481:LEPBI RS08435
gene id: 456481:LEPBI_RS08435
uniprot id: B0SRL8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

456481:LEPBI RS04665
gene id: 456481:LEPBI_RS04665
uniprot id: B0SMD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

456481:LEPBI RS07035
gene id: 456481:LEPBI_RS07035
uniprot id: B0SPX6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

456481:LEPBI RS17360
gene id: 456481:LEPBI_RS17360
uniprot id: B0STR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

456481:LEPBI RS07505
gene id: 456481:LEPBI_RS07505
uniprot id: B0SQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

456481:LEPBI RS13065
gene id: 456481:LEPBI_RS13065
uniprot id: B0SML1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

456481:LEPBI RS08555
gene id: 456481:LEPBI_RS08555
uniprot id: B0SRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

456481:LEPBI RS06390
gene id: 456481:LEPBI_RS06390
uniprot id: B0SP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane
messages: Mitochondrion inner membrane

456481:LEPBI RS03380
gene id: 456481:LEPBI_RS03380
uniprot id: B0SKR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS03175
gene id: 456481:LEPBI_RS03175
uniprot id: B0SKM1
names: Similarity
messages: Belongs to the UPF0162 family.

456481:LEPBI RS10075
gene id: 456481:LEPBI_RS10075
uniprot id: B0SSQ2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

456481:LEPBI RS06270
gene id: 456481:LEPBI_RS06270
uniprot id: B0SP67
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS04595
gene id: 456481:LEPBI_RS04595
uniprot id: B0SMB7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

456481:LEPBI RS10570
gene id: 456481:LEPBI_RS10570
uniprot id: B0ST02
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

456481:LEPBI RS00850
gene id: 456481:LEPBI_RS00850
uniprot id: B0SK75
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

456481:LEPBI RS18045
gene id: 456481:LEPBI_RS18045
uniprot id: B0SU49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

456481:LEPBI RS16005
gene id: 456481:LEPBI_RS16005
uniprot id: B0SQT6
names: Similarity
messages: Belongs to the TelA family.

456481:LEPBI RS01270
gene id: 456481:LEPBI_RS01270
uniprot id: B0STJ0
names: Similarity
messages: Belongs to the threonine synthase family.

456481:LEPBI RS05270
gene id: 456481:LEPBI_RS05270
uniprot id: B0SN09
names: Similarity
messages: Belongs to the MQO family.

456481:LEPBI RS09585
gene id: 456481:LEPBI_RS09585
uniprot id: B0SSF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

456481:LEPBI RS08245
gene id: 456481:LEPBI_RS08245
uniprot id: B0SR75
names: Similarity
messages: Belongs to the UPF0102 family.

456481:LEPBI RS16905
gene id: 456481:LEPBI_RS16905
uniprot id: B0SRX5
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

456481:LEPBI RS00020
gene id: 456481:LEPBI_RS00020
uniprot id: B0SK31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

456481:LEPBI RS10550
gene id: 456481:LEPBI_RS10550
uniprot id: B0SSZ8
names: Similarity
messages: Belongs to the DEAD box helicase family.

456481:LEPBI RS06870
gene id: 456481:LEPBI_RS06870
uniprot id: B0SPU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

456481:LEPBI RS08415
gene id: 456481:LEPBI_RS08415
uniprot id: B0SRL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

456481:LEPBI RS01095
gene id: 456481:LEPBI_RS01095
uniprot id: B0SKC9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS08050
gene id: 456481:LEPBI_RS08050
uniprot id: B0SR36
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

456481:LEPBI RS07655
gene id: 456481:LEPBI_RS07655
uniprot id: B0SQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

456481:LEPBI RS09695
gene id: 456481:LEPBI_RS09695
uniprot id: B0SSH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

456481:LEPBI RS06890
gene id: 456481:LEPBI_RS06890
uniprot id: B0SPU8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS07735
gene id: 456481:LEPBI_RS07735
uniprot id: B0SQL8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

456481:LEPBI RS17085
gene id: 456481:LEPBI_RS17085
uniprot id: B0STK6
names: Similarity
messages: Belongs to the ParB family.

456481:LEPBI RS14140
gene id: 456481:LEPBI_RS14140
uniprot id: B0SNU3
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS05190
gene id: 456481:LEPBI_RS05190
uniprot id: B0SMZ3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

456481:LEPBI RS15190
gene id: 456481:LEPBI_RS15190
uniprot id: B0SQ17
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS14120
gene id: 456481:LEPBI_RS14120
uniprot id: B0SNT9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS11245
gene id: 456481:LEPBI_RS11245
uniprot id: B0STD3
names: Similarity
messages: Belongs to the DinB family.

456481:LEPBI RS16015
gene id: 456481:LEPBI_RS16015
uniprot id: B0SQT8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS07710
gene id: 456481:LEPBI_RS07710
uniprot id: B0SQL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

456481:LEPBI RS06320
gene id: 456481:LEPBI_RS06320
uniprot id: B0SP77
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

456481:LEPBI RS07220
gene id: 456481:LEPBI_RS07220
uniprot id: B0SQB9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

456481:LEPBI RS12235
gene id: 456481:LEPBI_RS12235
uniprot id: B0SLI2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS06025
gene id: 456481:LEPBI_RS06025
uniprot id: B0SNR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

456481:LEPBI RS07890
gene id: 456481:LEPBI_RS07890
uniprot id: B0SR05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

456481:LEPBI RS09425
gene id: 456481:LEPBI_RS09425
uniprot id: B0SSC2
names: Similarity
messages: Belongs to the BolA/IbaG family.

456481:LEPBI RS08805
gene id: 456481:LEPBI_RS08805
uniprot id: B0SRU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

456481:LEPBI RS13195
gene id: 456481:LEPBI_RS13195
uniprot id: B0SMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

456481:LEPBI RS05735
gene id: 456481:LEPBI_RS05735
uniprot id: B0SNK4
names: Similarity
messages: Belongs to the ALAD family.

456481:LEPBI RS03765
gene id: 456481:LEPBI_RS03765
uniprot id: B0SL88
names: Similarity
messages: Belongs to the pyruvate kinase family.

456481:LEPBI RS03660
gene id: 456481:LEPBI_RS03660
uniprot id: B0SL67
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

456481:LEPBI RS08680
gene id: 456481:LEPBI_RS08680
uniprot id: B0SRR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS03960
gene id: 456481:LEPBI_RS03960
uniprot id: B0SLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

456481:LEPBI RS18015
gene id: 456481:LEPBI_RS18015
uniprot id: B0SU43
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

456481:LEPBI RS04810
gene id: 456481:LEPBI_RS04810
uniprot id: B0SMF9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

456481:LEPBI RS01670
gene id: 456481:LEPBI_RS01670
uniprot id: B0SKD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

456481:LEPBI RS14730
gene id: 456481:LEPBI_RS14730
uniprot id: B0SPG9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

456481:LEPBI RS07970
gene id: 456481:LEPBI_RS07970
uniprot id: B0SR21
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

456481:LEPBI RS14000
gene id: 456481:LEPBI_RS14000
uniprot id: B0SNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

456481:LEPBI RS16615
gene id: 456481:LEPBI_RS16615
uniprot id: B0SRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

456481:LEPBI RS09670
gene id: 456481:LEPBI_RS09670
uniprot id: B0SSH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

456481:LEPBI RS04480
gene id: 456481:LEPBI_RS04480
uniprot id: B0SLY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

456481:LEPBI RS13035
gene id: 456481:LEPBI_RS13035
uniprot id: B0SM99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

456481:LEPBI RS12780
gene id: 456481:LEPBI_RS12780
uniprot id: B0SM47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS15060
gene id: 456481:LEPBI_RS15060
uniprot id: B0SPN6
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS16590
gene id: 456481:LEPBI_RS16590
uniprot id: B0SRF7
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

456481:LEPBI RS09375
gene id: 456481:LEPBI_RS09375
uniprot id: B0SSB2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

456481:LEPBI RS06695
gene id: 456481:LEPBI_RS06695
uniprot id: B0SPQ8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

456481:LEPBI RS06460
gene id: 456481:LEPBI_RS06460
uniprot id: B0SPA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

456481:LEPBI RS11840
gene id: 456481:LEPBI_RS11840
uniprot id: B0SKZ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

456481:LEPBI RS09995
gene id: 456481:LEPBI_RS09995
uniprot id: B0SSN6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

456481:LEPBI RS09960
gene id: 456481:LEPBI_RS09960
uniprot id: B0SSM9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

456481:LEPBI RS06540
gene id: 456481:LEPBI_RS06540
uniprot id: B0SPC1
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

456481:LEPBI RS07415
gene id: 456481:LEPBI_RS07415
uniprot id: B0SQF8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

456481:LEPBI RS04955
gene id: 456481:LEPBI_RS04955
uniprot id: B0SMI8
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS06590
gene id: 456481:LEPBI_RS06590
uniprot id: B0SPD0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

456481:LEPBI RS11960
gene id: 456481:LEPBI_RS11960
uniprot id: B0SL19
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS09285
gene id: 456481:LEPBI_RS09285
uniprot id: B0SS94
names: Similarity
messages: Belongs to the peptidase M1 family.

456481:LEPBI RS09445
gene id: 456481:LEPBI_RS09445
uniprot id: B0SSC6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

456481:LEPBI RS05155
gene id: 456481:LEPBI_RS05155
uniprot id: B0SMY6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

456481:LEPBI RS13030
gene id: 456481:LEPBI_RS13030
uniprot id: B0SM98
names: Similarity
messages: Belongs to the universal stress protein A family.

456481:LEPBI RS05315
gene id: 456481:LEPBI_RS05315
uniprot id: B0SN17
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

456481:LEPBI RS09565
gene id: 456481:LEPBI_RS09565
uniprot id: B0SSE9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

456481:LEPBI RS11440
gene id: 456481:LEPBI_RS11440
uniprot id: B0STG9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

456481:LEPBI RS10265
gene id: 456481:LEPBI_RS10265
uniprot id: B0SSU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

456481:LEPBI RS07910
gene id: 456481:LEPBI_RS07910
uniprot id: B0SR09
names: Similarity
messages: Belongs to the band 7/mec-2 family.

456481:LEPBI RS16990
gene id: 456481:LEPBI_RS16990
uniprot id: B0SRY7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

456481:LEPBI RS03315
gene id: 456481:LEPBI_RS03315
uniprot id: B0SKP9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

456481:LEPBI RS06205
gene id: 456481:LEPBI_RS06205
uniprot id: B0SP55
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

456481:LEPBI RS11445
gene id: 456481:LEPBI_RS11445
uniprot id: B0STH0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

456481:LEPBI RS00285
gene id: 456481:LEPBI_RS00285
uniprot id: B0SJP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

456481:LEPBI RS15685
gene id: 456481:LEPBI_RS15685
uniprot id: B0SQB6
names: Similarity
messages: Belongs to the peptidase S1C family.

456481:LEPBI RS09095
gene id: 456481:LEPBI_RS09095
uniprot id: B0SS56
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

456481:LEPBI RS04760
gene id: 456481:LEPBI_RS04760
uniprot id: B0SME9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

456481:LEPBI RS09755
gene id: 456481:LEPBI_RS09755
uniprot id: B0SSI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

456481:LEPBI RS04945
gene id: 456481:LEPBI_RS04945
uniprot id: B0SMI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS10275
gene id: 456481:LEPBI_RS10275
uniprot id: B0SSU2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

456481:LEPBI RS18695
gene id: 456481:LEPBI_RS18695
uniprot id: B0SUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

456481:LEPBI RS17965
gene id: 456481:LEPBI_RS17965
uniprot id: B0SU33
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

456481:LEPBI RS01415
gene id: 456481:LEPBI_RS01415
uniprot id: B0SJ24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

456481:LEPBI RS05700
gene id: 456481:LEPBI_RS05700
uniprot id: B0SNJ7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

456481:LEPBI RS13345
gene id: 456481:LEPBI_RS13345
uniprot id: B0SMR8
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

456481:LEPBI RS11530
gene id: 456481:LEPBI_RS11530
uniprot id: B0SKT3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

456481:LEPBI RS15700
gene id: 456481:LEPBI_RS15700
uniprot id: B0SQM4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

456481:LEPBI RS01325
gene id: 456481:LEPBI_RS01325
uniprot id: B0STK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

456481:LEPBI RS12860
gene id: 456481:LEPBI_RS12860
uniprot id: B0SM63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

456481:LEPBI RS02345
gene id: 456481:LEPBI_RS02345
uniprot id: B0SJ28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

456481:LEPBI RS03490
gene id: 456481:LEPBI_RS03490
uniprot id: B0SL33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

456481:LEPBI RS04135
gene id: 456481:LEPBI_RS04135
uniprot id: B0SLR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

456481:LEPBI RS14505
gene id: 456481:LEPBI_RS14505
uniprot id: B0SP17
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS07725
gene id: 456481:LEPBI_RS07725
uniprot id: B0SQL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

456481:LEPBI RS03985
gene id: 456481:LEPBI_RS03985
uniprot id: B0SLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS09040
gene id: 456481:LEPBI_RS09040
uniprot id: B0SS45
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

456481:LEPBI RS00365
gene id: 456481:LEPBI_RS00365
uniprot id: B0SJQ6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS01685
gene id: 456481:LEPBI_RS01685
uniprot id: B0SKD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

456481:LEPBI RS13060
gene id: 456481:LEPBI_RS13060
uniprot id: B0SMA4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

456481:LEPBI RS09155
gene id: 456481:LEPBI_RS09155
uniprot id: B0SS68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

456481:LEPBI RS09500
gene id: 456481:LEPBI_RS09500
uniprot id: B0SSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

456481:LEPBI RS08705
gene id: 456481:LEPBI_RS08705
uniprot id: B0SRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

456481:LEPBI RS01480
gene id: 456481:LEPBI_RS01480
uniprot id: B0SJE9
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS10055
gene id: 456481:LEPBI_RS10055
uniprot id: B0SSP8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

456481:LEPBI RS18660
gene id: 456481:LEPBI_RS18660
uniprot id: B0SUH7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

456481:LEPBI RS11390
gene id: 456481:LEPBI_RS11390
uniprot id: B0STG3
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS14645
gene id: 456481:LEPBI_RS14645
uniprot id: B0SPF1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

456481:LEPBI RS09610
gene id: 456481:LEPBI_RS09610
uniprot id: B0SSF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

456481:LEPBI RS05790
gene id: 456481:LEPBI_RS05790
uniprot id: B0SNL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

456481:LEPBI RS00150
gene id: 456481:LEPBI_RS00150
uniprot id: B0SK56
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

456481:LEPBI RS04285
gene id: 456481:LEPBI_RS04285
uniprot id: B0SLU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

456481:LEPBI RS12115
gene id: 456481:LEPBI_RS12115
uniprot id: B0SLF8
names: Similarity
messages: Belongs to the peptidase C69 family.

456481:LEPBI RS08785
gene id: 456481:LEPBI_RS08785
uniprot id: B0SRT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

456481:LEPBI RS12010
gene id: 456481:LEPBI_RS12010
uniprot id: B0SL28
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

456481:LEPBI RS10165
gene id: 456481:LEPBI_RS10165
uniprot id: B0SSS0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

456481:LEPBI RS16130
gene id: 456481:LEPBI_RS16130
uniprot id: B0SQW1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

456481:LEPBI RS08600
gene id: 456481:LEPBI_RS08600
uniprot id: B0SRQ2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS08780
gene id: 456481:LEPBI_RS08780
uniprot id: B0SRT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS09765
gene id: 456481:LEPBI_RS09765
uniprot id: B0SSI9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

456481:LEPBI RS07180
gene id: 456481:LEPBI_RS07180
uniprot id: B0SQ03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

456481:LEPBI RS00415
gene id: 456481:LEPBI_RS00415
uniprot id: B0SJT2
names: Similarity
messages: Belongs to the TlyA family.

456481:LEPBI RS06290
gene id: 456481:LEPBI_RS06290
uniprot id: B0SP71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

456481:LEPBI RS10230
gene id: 456481:LEPBI_RS10230
uniprot id: B0SST3
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS07795
gene id: 456481:LEPBI_RS07795
uniprot id: B0SQY6
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

456481:LEPBI RS09515
gene id: 456481:LEPBI_RS09515
uniprot id: B0SSE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

456481:LEPBI RS18500
gene id: 456481:LEPBI_RS18500
uniprot id: B0SUE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

456481:LEPBI RS00315
gene id: 456481:LEPBI_RS00315
uniprot id: B0SJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

456481:LEPBI RS07215
gene id: 456481:LEPBI_RS07215
uniprot id: B0SQ10
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

456481:LEPBI RS14340
gene id: 456481:LEPBI_RS14340
uniprot id: B0SNY2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

456481:LEPBI RS16610
gene id: 456481:LEPBI_RS16610
uniprot id: B0SRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

456481:LEPBI RS10370
gene id: 456481:LEPBI_RS10370
uniprot id: B0SSW1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

456481:LEPBI RS08030
gene id: 456481:LEPBI_RS08030
uniprot id: B0SR32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

456481:LEPBI RS06375
gene id: 456481:LEPBI_RS06375
uniprot id: B0SP88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

456481:LEPBI RS12105
gene id: 456481:LEPBI_RS12105
uniprot id: B0SLF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS17010
gene id: 456481:LEPBI_RS17010
uniprot id: B0SRZ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

456481:LEPBI RS09195
gene id: 456481:LEPBI_RS09195
uniprot id: B0SS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

456481:LEPBI RS04060
gene id: 456481:LEPBI_RS04060
uniprot id: B0SLQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

456481:LEPBI RS09255
gene id: 456481:LEPBI_RS09255
uniprot id: B0SS88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

456481:LEPBI RS06670
gene id: 456481:LEPBI_RS06670
uniprot id: B0SPE5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

456481:LEPBI RS00980
gene id: 456481:LEPBI_RS00980
uniprot id: B0SK97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

456481:LEPBI RS10630
gene id: 456481:LEPBI_RS10630
uniprot id: B0ST16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

456481:LEPBI RS15330
gene id: 456481:LEPBI_RS15330
uniprot id: B0SQ45
names: Similarity
messages: Belongs to the AHA1 family.

456481:LEPBI RS08675
gene id: 456481:LEPBI_RS08675
uniprot id: B0SRR7
names: Subcellular Location Annotation
messages: Cytoplasm

456481:LEPBI RS11950
gene id: 456481:LEPBI_RS11950
uniprot id: B0SL17
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS15850
gene id: 456481:LEPBI_RS15850
uniprot id: B0SQQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS17050
gene id: 456481:LEPBI_RS17050
uniprot id: B0SRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

456481:LEPBI RS11930
gene id: 456481:LEPBI_RS11930
uniprot id: B0SL13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS00465
gene id: 456481:LEPBI_RS00465
uniprot id: B0SJR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

456481:LEPBI RS13305
gene id: 456481:LEPBI_RS13305
uniprot id: B0SMQ9
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS05035
gene id: 456481:LEPBI_RS05035
uniprot id: B0SMK5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

456481:LEPBI RS12855
gene id: 456481:LEPBI_RS12855
uniprot id: B0SM62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

456481:LEPBI RS07835
gene id: 456481:LEPBI_RS07835
uniprot id: B0SQZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

456481:LEPBI RS02230
gene id: 456481:LEPBI_RS02230
uniprot id: B0SJM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

456481:LEPBI RS15100
gene id: 456481:LEPBI_RS15100
uniprot id: B0SPP4
names: Similarity
messages: Belongs to the pirin family.

456481:LEPBI RS08685
gene id: 456481:LEPBI_RS08685
uniprot id: B0SRR9
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS02975
gene id: 456481:LEPBI_RS02975
uniprot id: B0SKI4
names: Similarity
messages: Belongs to the TPP enzyme family.

456481:LEPBI RS06470
gene id: 456481:LEPBI_RS06470
uniprot id: B0SPA7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS09685
gene id: 456481:LEPBI_RS09685
uniprot id: B0SSH3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

456481:LEPBI RS06480
gene id: 456481:LEPBI_RS06480
uniprot id: B0SPA9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

456481:LEPBI RS08220
gene id: 456481:LEPBI_RS08220
uniprot id: B0SR70
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

456481:LEPBI RS06520
gene id: 456481:LEPBI_RS06520
uniprot id: B0SPB7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS11505
gene id: 456481:LEPBI_RS11505
uniprot id: B0STI1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS09800
gene id: 456481:LEPBI_RS09800
uniprot id: B0SSJ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

456481:LEPBI RS18050
gene id: 456481:LEPBI_RS18050
uniprot id: B0SU50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

456481:LEPBI RS18125
gene id: 456481:LEPBI_RS18125
uniprot id: B0SU67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS16545
gene id: 456481:LEPBI_RS16545
uniprot id: B0SRE8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

456481:LEPBI RS13870
gene id: 456481:LEPBI_RS13870
uniprot id: B0SND4
names: Similarity
messages: Belongs to the DEAD box helicase family.

456481:LEPBI RS08285
gene id: 456481:LEPBI_RS08285
uniprot id: B0SR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS14230
gene id: 456481:LEPBI_RS14230
uniprot id: B0SNW1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

456481:LEPBI RS06875
gene id: 456481:LEPBI_RS06875
uniprot id: B0SPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

456481:LEPBI RS01545
gene id: 456481:LEPBI_RS01545
uniprot id: B0SJE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

456481:LEPBI RS10375
gene id: 456481:LEPBI_RS10375
uniprot id: B0SSW2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

456481:LEPBI RS10430
gene id: 456481:LEPBI_RS10430
uniprot id: B0SSX3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

456481:LEPBI RS05085
gene id: 456481:LEPBI_RS05085
uniprot id: B0SMX2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS18255
gene id: 456481:LEPBI_RS18255
uniprot id: B0SU94
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS05660
gene id: 456481:LEPBI_RS05660
uniprot id: B0SNI9
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS18235
gene id: 456481:LEPBI_RS18235
uniprot id: B0SU90
names: Similarity
messages: Belongs to the CutA family.

456481:LEPBI RS07270
gene id: 456481:LEPBI_RS07270
uniprot id: B0SQC9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

456481:LEPBI RS15810
gene id: 456481:LEPBI_RS15810
uniprot id: B0SQP6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

456481:LEPBI RS02330
gene id: 456481:LEPBI_RS02330
uniprot id: B0SJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

456481:LEPBI RS00720
gene id: 456481:LEPBI_RS00720
uniprot id: B0SJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

456481:LEPBI RS08845
gene id: 456481:LEPBI_RS08845
uniprot id: B0SS06
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

456481:LEPBI RS16150
gene id: 456481:LEPBI_RS16150
uniprot id: B0SQW5
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS00700
gene id: 456481:LEPBI_RS00700
uniprot id: B0SJV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

456481:LEPBI RS07930
gene id: 456481:LEPBI_RS07930
uniprot id: B0SR13
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

456481:LEPBI RS18075
gene id: 456481:LEPBI_RS18075
uniprot id: B0SU55
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS04675
gene id: 456481:LEPBI_RS04675
uniprot id: B0SMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS03515
gene id: 456481:LEPBI_RS03515
uniprot id: B0SL38
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS08420
gene id: 456481:LEPBI_RS08420
uniprot id: B0SRL5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

456481:LEPBI RS15520
gene id: 456481:LEPBI_RS15520
uniprot id: B0SQ83
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

456481:LEPBI RS03710
gene id: 456481:LEPBI_RS03710
uniprot id: B0SL77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

456481:LEPBI RS09380
gene id: 456481:LEPBI_RS09380
uniprot id: B0SSB3
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

456481:LEPBI RS04755
gene id: 456481:LEPBI_RS04755
uniprot id: B0SME8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

456481:LEPBI RS09605
gene id: 456481:LEPBI_RS09605
uniprot id: B0SSF7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS15050
gene id: 456481:LEPBI_RS15050
uniprot id: B0SPN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

456481:LEPBI RS00920
gene id: 456481:LEPBI_RS00920
uniprot id: B0SK85
names: Similarity
messages: Belongs to the aspartokinase family.

456481:LEPBI RS10535
gene id: 456481:LEPBI_RS10535
uniprot id: B0SSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

456481:LEPBI RS04200
gene id: 456481:LEPBI_RS04200
uniprot id: B0SLT1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

456481:LEPBI RS13155
gene id: 456481:LEPBI_RS13155
uniprot id: B0SMM9
names: Similarity
messages: Belongs to the ycf81 family.

456481:LEPBI RS11850
gene id: 456481:LEPBI_RS11850
uniprot id: B0SKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

456481:LEPBI RS03555
gene id: 456481:LEPBI_RS03555
uniprot id: B0SL46
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-67 and Arg-70) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

456481:LEPBI RS12885
gene id: 456481:LEPBI_RS12885
uniprot id: B0SM68
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

456481:LEPBI RS01240
gene id: 456481:LEPBI_RS01240
uniprot id: B0STI4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

456481:LEPBI RS09180
gene id: 456481:LEPBI_RS09180
uniprot id: B0SS73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

456481:LEPBI RS16330
gene id: 456481:LEPBI_RS16330
uniprot id: B0SRA6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS04520
gene id: 456481:LEPBI_RS04520
uniprot id: B0SLZ4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

456481:LEPBI RS13550
gene id: 456481:LEPBI_RS13550
uniprot id: B0SMW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

456481:LEPBI RS10665
gene id: 456481:LEPBI_RS10665
uniprot id: B0ST22
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

456481:LEPBI RS09015
gene id: 456481:LEPBI_RS09015
uniprot id: B0SS40
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

456481:LEPBI RS04090
gene id: 456481:LEPBI_RS04090
uniprot id: B0SLQ9
names: Similarity
messages: Belongs to the TrpF family.

456481:LEPBI RS11535
gene id: 456481:LEPBI_RS11535
uniprot id: B0SKT4
names: Subcellular Location Annotation
messages: Periplasmic flagellum

456481:LEPBI RS11460
gene id: 456481:LEPBI_RS11460
uniprot id: B0STH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS17570
gene id: 456481:LEPBI_RS17570
uniprot id: B0STV3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

456481:LEPBI RS16250
gene id: 456481:LEPBI_RS16250
uniprot id: B0SR91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

456481:LEPBI RS15940
gene id: 456481:LEPBI_RS15940
uniprot id: B0SQS3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS13960
gene id: 456481:LEPBI_RS13960
uniprot id: B0SNF3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

456481:LEPBI RS07870
gene id: 456481:LEPBI_RS07870
uniprot id: B0SR01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

456481:LEPBI RS00325
gene id: 456481:LEPBI_RS00325
uniprot id: B0SJP8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

456481:LEPBI RS08305
gene id: 456481:LEPBI_RS08305
uniprot id: B0SRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

456481:LEPBI RS14500
gene id: 456481:LEPBI_RS14500
uniprot id: B0SP16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

456481:LEPBI RS08195
gene id: 456481:LEPBI_RS08195
uniprot id: B0SR65
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

456481:LEPBI RS08375
gene id: 456481:LEPBI_RS08375
uniprot id: B0SRK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Membrane

456481:LEPBI RS07685
gene id: 456481:LEPBI_RS07685
uniprot id: B0SQK8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

456481:LEPBI RS14845
gene id: 456481:LEPBI_RS14845
uniprot id: B0SPJ2
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS15460
gene id: 456481:LEPBI_RS15460
uniprot id: B0SQ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

456481:LEPBI RS13420
gene id: 456481:LEPBI_RS13420
uniprot id: B0SMT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS08770
gene id: 456481:LEPBI_RS08770
uniprot id: B0SRT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

456481:LEPBI RS07510
gene id: 456481:LEPBI_RS07510
uniprot id: B0SQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

456481:LEPBI RS15425
gene id: 456481:LEPBI_RS15425
uniprot id: B0SQ63
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

456481:LEPBI RS05800
gene id: 456481:LEPBI_RS05800
uniprot id: B0SNL8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

456481:LEPBI RS01505
gene id: 456481:LEPBI_RS01505
uniprot id: B0SJF4
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

456481:LEPBI RS03410
gene id: 456481:LEPBI_RS03410
uniprot id: B0SKR8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

456481:LEPBI RS03670
gene id: 456481:LEPBI_RS03670
uniprot id: B0SL69
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS07125
gene id: 456481:LEPBI_RS07125
uniprot id: B0SPZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

456481:LEPBI RS01155
gene id: 456481:LEPBI_RS01155
uniprot id: B0SKG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

456481:LEPBI RS06300
gene id: 456481:LEPBI_RS06300
uniprot id: B0SP73
names: Similarity
messages: Belongs to the Nth/MutY family.

456481:LEPBI RS09730
gene id: 456481:LEPBI_RS09730
uniprot id: B0SSI2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex (By similarity).
messages: The streptomycin sensitive allele is dominant to the resistant allele in L.biflexa.
messages: With S4 and S5 plays an important role in translational accuracy.

456481:LEPBI RS07335
gene id: 456481:LEPBI_RS07335
uniprot id: B0SQE2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

456481:LEPBI RS06920
gene id: 456481:LEPBI_RS06920
uniprot id: B0SPV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

456481:LEPBI RS05025
gene id: 456481:LEPBI_RS05025
uniprot id: B0SMK3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS13460
gene id: 456481:LEPBI_RS13460
uniprot id: B0SMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

456481:LEPBI RS00855
gene id: 456481:LEPBI_RS00855
uniprot id: B0SK76
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

456481:LEPBI RS09590
gene id: 456481:LEPBI_RS09590
uniprot id: B0SSF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

456481:LEPBI RS02520
gene id: 456481:LEPBI_RS02520
uniprot id: B0SJ57
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

456481:LEPBI RS05535
gene id: 456481:LEPBI_RS05535
uniprot id: B0SN60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS06455
gene id: 456481:LEPBI_RS06455
uniprot id: B0SPA4
names: Similarity
messages: Belongs to the peptidase S41A family.

456481:LEPBI RS10335
gene id: 456481:LEPBI_RS10335
uniprot id: B0SSV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

456481:LEPBI RS06810
gene id: 456481:LEPBI_RS06810
uniprot id: B0SPT2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

456481:LEPBI RS04240
gene id: 456481:LEPBI_RS04240
uniprot id: B0SLT9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

456481:LEPBI RS06435
gene id: 456481:LEPBI_RS06435
uniprot id: B0SPA0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

456481:LEPBI RS09135
gene id: 456481:LEPBI_RS09135
uniprot id: B0SS64
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

456481:LEPBI RS00870
gene id: 456481:LEPBI_RS00870
uniprot id: B0SK79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS00125
gene id: 456481:LEPBI_RS00125
uniprot id: B0SK28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

456481:LEPBI RS02590
gene id: 456481:LEPBI_RS02590
uniprot id: B0SJG6
names: Similarity
messages: Belongs to the SufE family.

456481:LEPBI RS16115
gene id: 456481:LEPBI_RS16115
uniprot id: B0SQV8
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS00040
gene id: 456481:LEPBI_RS00040
uniprot id: B0SK35
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

456481:LEPBI RS10615
gene id: 456481:LEPBI_RS10615
uniprot id: B0ST13
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

456481:LEPBI RS15540
gene id: 456481:LEPBI_RS15540
uniprot id: B0SQ87
names: Similarity
messages: Belongs to the thioredoxin family.

456481:LEPBI RS15300
gene id: 456481:LEPBI_RS15300
uniprot id: B0SQ39
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

456481:LEPBI RS06530
gene id: 456481:LEPBI_RS06530
uniprot id: B0SPB9
names: Subcellular Location Annotation
messages: Periplasmic flagellum

456481:LEPBI RS12500
gene id: 456481:LEPBI_RS12500
uniprot id: B0SLN5
names: Similarity
messages: Belongs to the Dps family.

456481:LEPBI RS06195
gene id: 456481:LEPBI_RS06195
uniprot id: B0SP53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS15665
gene id: 456481:LEPBI_RS15665
uniprot id: B0SQB2
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS01330
gene id: 456481:LEPBI_RS01330
uniprot id: B0STK2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

456481:LEPBI RS00250
gene id: 456481:LEPBI_RS00250
uniprot id: B0SK53
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

456481:LEPBI RS12025
gene id: 456481:LEPBI_RS12025
uniprot id: B0SLD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

456481:LEPBI RS06570
gene id: 456481:LEPBI_RS06570
uniprot id: B0SPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

456481:LEPBI RS15325
gene id: 456481:LEPBI_RS15325
uniprot id: B0SQ44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

456481:LEPBI RS14740
gene id: 456481:LEPBI_RS14740
uniprot id: B0SPH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

456481:LEPBI RS13215
gene id: 456481:LEPBI_RS13215
uniprot id: B0SMP1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

456481:LEPBI RS08755
gene id: 456481:LEPBI_RS08755
uniprot id: B0SRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS13205
gene id: 456481:LEPBI_RS13205
uniprot id: B0SMN9
names: Similarity
messages: Belongs to the SCO1/2 family.

456481:LEPBI RS16200
gene id: 456481:LEPBI_RS16200
uniprot id: B0SQX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

456481:LEPBI RS01465
gene id: 456481:LEPBI_RS01465
uniprot id: B0SJE6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

456481:LEPBI RS05070
gene id: 456481:LEPBI_RS05070
uniprot id: B0SMW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

456481:LEPBI RS04640
gene id: 456481:LEPBI_RS04640
uniprot id: B0SMC6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

456481:LEPBI RS01230
gene id: 456481:LEPBI_RS01230
uniprot id: B0STI2
names: Similarity
messages: Belongs to the GARS family.

456481:LEPBI RS11510
gene id: 456481:LEPBI_RS11510
uniprot id: B0SKS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

456481:LEPBI RS04555
gene id: 456481:LEPBI_RS04555
uniprot id: B0SMA9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

456481:LEPBI RS09000
gene id: 456481:LEPBI_RS09000
uniprot id: B0SS37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

456481:LEPBI RS18360
gene id: 456481:LEPBI_RS18360
uniprot id: B0SUB5
names: Similarity
messages: Belongs to the pirin family.

456481:LEPBI RS16070
gene id: 456481:LEPBI_RS16070
uniprot id: B0SQU9
names: Similarity
messages: Belongs to the peptidase S8 family.

456481:LEPBI RS14800
gene id: 456481:LEPBI_RS14800
uniprot id: B0SPI3
names: Similarity
messages: Belongs to the SCO1/2 family.

456481:LEPBI RS08430
gene id: 456481:LEPBI_RS08430
uniprot id: B0SRL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

456481:LEPBI RS15355
gene id: 456481:LEPBI_RS15355
uniprot id: B0SQ50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

456481:LEPBI RS04475
gene id: 456481:LEPBI_RS04475
uniprot id: B0SLY5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

456481:LEPBI RS02340
gene id: 456481:LEPBI_RS02340
uniprot id: B0SJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

456481:LEPBI RS02210
gene id: 456481:LEPBI_RS02210
uniprot id: B0SJM0
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS12315
gene id: 456481:LEPBI_RS12315
uniprot id: B0SLJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

456481:LEPBI RS11825
gene id: 456481:LEPBI_RS11825
uniprot id: B0SKZ1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

456481:LEPBI RS12645
gene id: 456481:LEPBI_RS12645
uniprot id: B0SM20
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS05825
gene id: 456481:LEPBI_RS05825
uniprot id: B0SNM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

456481:LEPBI RS09150
gene id: 456481:LEPBI_RS09150
uniprot id: B0SS67
names: Similarity
messages: Belongs to the ClpA/ClpB family.

456481:LEPBI RS00860
gene id: 456481:LEPBI_RS00860
uniprot id: B0SK77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

456481:LEPBI RS14075
gene id: 456481:LEPBI_RS14075
uniprot id: B0SNH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS08760
gene id: 456481:LEPBI_RS08760
uniprot id: B0SRT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

456481:LEPBI RS12765
gene id: 456481:LEPBI_RS12765
uniprot id: B0SM44
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

456481:LEPBI RS11465
gene id: 456481:LEPBI_RS11465
uniprot id: B0STH4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

456481:LEPBI RS05870
gene id: 456481:LEPBI_RS05870
uniprot id: B0SNN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

456481:LEPBI RS09675
gene id: 456481:LEPBI_RS09675
uniprot id: B0SSH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

456481:LEPBI RS05065
gene id: 456481:LEPBI_RS05065
uniprot id: B0SMW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS09225
gene id: 456481:LEPBI_RS09225
uniprot id: B0SS82
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

456481:LEPBI RS15045
gene id: 456481:LEPBI_RS15045
uniprot id: B0SPN3
names: Similarity
messages: Belongs to the MreC family.

456481:LEPBI RS15180
gene id: 456481:LEPBI_RS15180
uniprot id: B0SQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

456481:LEPBI RS11300
gene id: 456481:LEPBI_RS11300
uniprot id: B0STE5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

456481:LEPBI RS08510
gene id: 456481:LEPBI_RS08510
uniprot id: B0SRN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

456481:LEPBI RS07665
gene id: 456481:LEPBI_RS07665
uniprot id: B0SQK4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

456481:LEPBI RS11990
gene id: 456481:LEPBI_RS11990
uniprot id: B0SL24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

456481:LEPBI RS09630
gene id: 456481:LEPBI_RS09630
uniprot id: B0SSG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

456481:LEPBI RS05845
gene id: 456481:LEPBI_RS05845
uniprot id: B0SNM6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

456481:LEPBI RS06015
gene id: 456481:LEPBI_RS06015
uniprot id: B0SNR1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

456481:LEPBI RS07520
gene id: 456481:LEPBI_RS07520
uniprot id: B0SQH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

456481:LEPBI RS11770
gene id: 456481:LEPBI_RS11770
uniprot id: B0SKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS16850
gene id: 456481:LEPBI_RS16850
uniprot id: B0SRW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS08540
gene id: 456481:LEPBI_RS08540
uniprot id: B0SRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

456481:LEPBI RS09395
gene id: 456481:LEPBI_RS09395
uniprot id: B0SSB6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

456481:LEPBI RS07225
gene id: 456481:LEPBI_RS07225
uniprot id: B0SQC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

456481:LEPBI RS06445
gene id: 456481:LEPBI_RS06445
uniprot id: B0SPA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

456481:LEPBI RS15340
gene id: 456481:LEPBI_RS15340
uniprot id: B0SQ47
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

456481:LEPBI RS07605
gene id: 456481:LEPBI_RS07605
uniprot id: B0SQJ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS15765
gene id: 456481:LEPBI_RS15765
uniprot id: B0SQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

456481:LEPBI RS00460
gene id: 456481:LEPBI_RS00460
uniprot id: B0SJR6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

456481:LEPBI RS16910
gene id: 456481:LEPBI_RS16910
uniprot id: B0SRX6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homomer.

456481:LEPBI RS08985
gene id: 456481:LEPBI_RS08985
uniprot id: B0SS34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS09790
gene id: 456481:LEPBI_RS09790
uniprot id: B0SSJ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS09125
gene id: 456481:LEPBI_RS09125
uniprot id: B0SS62
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

456481:LEPBI RS16695
gene id: 456481:LEPBI_RS16695
uniprot id: B0SRH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

456481:LEPBI RS11935
gene id: 456481:LEPBI_RS11935
uniprot id: B0SL14
names: Similarity
messages: Belongs to the FrhG family.

456481:LEPBI RS00810
gene id: 456481:LEPBI_RS00810
uniprot id: B0SJY7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS15830
gene id: 456481:LEPBI_RS15830
uniprot id: B0SQQ0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

456481:LEPBI RS01190
gene id: 456481:LEPBI_RS01190
uniprot id: B0SKF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

456481:LEPBI RS09580
gene id: 456481:LEPBI_RS09580
uniprot id: B0SSF2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

456481:LEPBI RS06610
gene id: 456481:LEPBI_RS06610
uniprot id: B0SPD4
names: Similarity
messages: Belongs to the peptidase M16 family.

456481:LEPBI RS09725
gene id: 456481:LEPBI_RS09725
uniprot id: B0SSI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

456481:LEPBI RS08645
gene id: 456481:LEPBI_RS08645
uniprot id: B0SRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

456481:LEPBI RS00030
gene id: 456481:LEPBI_RS00030
uniprot id: B0SK33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

456481:LEPBI RS02940
gene id: 456481:LEPBI_RS02940
uniprot id: B0SKH8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

456481:LEPBI RS05430
gene id: 456481:LEPBI_RS05430
uniprot id: B0SN40
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

456481:LEPBI RS16505
gene id: 456481:LEPBI_RS16505
uniprot id: B0SRE0
names: Similarity
messages: Belongs to the ArsC family.

456481:LEPBI RS06165
gene id: 456481:LEPBI_RS06165
uniprot id: B0SP47
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS08775
gene id: 456481:LEPBI_RS08775
uniprot id: B0SRT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS15900
gene id: 456481:LEPBI_RS15900
uniprot id: B0SQR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

456481:LEPBI RS06930
gene id: 456481:LEPBI_RS06930
uniprot id: B0SPV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

456481:LEPBI RS13590
gene id: 456481:LEPBI_RS13590
uniprot id: B0SN75
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

456481:LEPBI RS12545
gene id: 456481:LEPBI_RS12545
uniprot id: B0SM00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

456481:LEPBI RS00770
gene id: 456481:LEPBI_RS00770
uniprot id: B0SJZ8
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS05655
gene id: 456481:LEPBI_RS05655
uniprot id: B0SNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

456481:LEPBI RS08835
gene id: 456481:LEPBI_RS08835
uniprot id: B0SS04
names: Similarity
messages: Belongs to the peptidase M24B family.

456481:LEPBI RS09055
gene id: 456481:LEPBI_RS09055
uniprot id: B0SS48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

456481:LEPBI RS17275
gene id: 456481:LEPBI_RS17275
uniprot id: B0STP5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

456481:LEPBI RS05865
gene id: 456481:LEPBI_RS05865
uniprot id: B0SNN0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

456481:LEPBI RS00420
gene id: 456481:LEPBI_RS00420
uniprot id: B0SJT3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

456481:LEPBI RS02530
gene id: 456481:LEPBI_RS02530
uniprot id: B0SJ61
names: Similarity
messages: Belongs to the phosphohexose mutase family.

456481:LEPBI RS09645
gene id: 456481:LEPBI_RS09645
uniprot id: B0SSG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

456481:LEPBI RS03570
gene id: 456481:LEPBI_RS03570
uniprot id: B0SL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

456481:LEPBI RS14110
gene id: 456481:LEPBI_RS14110
uniprot id: B0SNT7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS09540
gene id: 456481:LEPBI_RS09540
uniprot id: B0SSE5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

456481:LEPBI RS13535
gene id: 456481:LEPBI_RS13535
uniprot id: B0SMV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

456481:LEPBI RS12070
gene id: 456481:LEPBI_RS12070
uniprot id: B0SLE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

456481:LEPBI RS18625
gene id: 456481:LEPBI_RS18625
uniprot id: B0SUH0
names: Similarity
messages: Belongs to the UPF0235 family.

456481:LEPBI RS09070
gene id: 456481:LEPBI_RS09070
uniprot id: B0SS51
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS09495
gene id: 456481:LEPBI_RS09495
uniprot id: B0SSD6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

456481:LEPBI RS09615
gene id: 456481:LEPBI_RS09615
uniprot id: B0SSF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

456481:LEPBI RS04145
gene id: 456481:LEPBI_RS04145
uniprot id: B0SLS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

456481:LEPBI RS16245
gene id: 456481:LEPBI_RS16245
uniprot id: B0SR90
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS05580
gene id: 456481:LEPBI_RS05580
uniprot id: B0SN68
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS09855
gene id: 456481:LEPBI_RS09855
uniprot id: B0SSK7
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS06685
gene id: 456481:LEPBI_RS06685
uniprot id: B0SPE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

456481:LEPBI RS10485
gene id: 456481:LEPBI_RS10485
uniprot id: B0SSY5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

456481:LEPBI RS11675
gene id: 456481:LEPBI_RS11675
uniprot id: B0SKW2
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS05710
gene id: 456481:LEPBI_RS05710
uniprot id: B0SNJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

456481:LEPBI RS11455
gene id: 456481:LEPBI_RS11455
uniprot id: B0STH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS09665
gene id: 456481:LEPBI_RS09665
uniprot id: B0SSG9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

456481:LEPBI RS04605
gene id: 456481:LEPBI_RS04605
uniprot id: B0SMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

456481:LEPBI RS16300
gene id: 456481:LEPBI_RS16300
uniprot id: B0SRA0
names: Similarity
messages: Belongs to the acylphosphatase family.

456481:LEPBI RS06355
gene id: 456481:LEPBI_RS06355
uniprot id: B0SP84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

456481:LEPBI RS10160
gene id: 456481:LEPBI_RS10160
uniprot id: B0SSR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

456481:LEPBI RS09575
gene id: 456481:LEPBI_RS09575
uniprot id: B0SSF1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

456481:LEPBI RS07485
gene id: 456481:LEPBI_RS07485
uniprot id: B0SQH0
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

456481:LEPBI RS16495
gene id: 456481:LEPBI_RS16495
uniprot id: B0SRD8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

456481:LEPBI RS10860
gene id: 456481:LEPBI_RS10860
uniprot id: B0ST62
names: Similarity
messages: Belongs to the UPF0175 family.

456481:LEPBI RS06575
gene id: 456481:LEPBI_RS06575
uniprot id: B0SPC7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

456481:LEPBI RS11625
gene id: 456481:LEPBI_RS11625
uniprot id: B0SKV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

456481:LEPBI RS08125
gene id: 456481:LEPBI_RS08125
uniprot id: B0SR51
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS11630
gene id: 456481:LEPBI_RS11630
uniprot id: A0A221LG20
uniprot id: B0SKV3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

456481:LEPBI RS06235
gene id: 456481:LEPBI_RS06235
uniprot id: B0SP61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

456481:LEPBI RS17825
gene id: 456481:LEPBI_RS17825
uniprot id: B0SU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

456481:LEPBI RS10780
gene id: 456481:LEPBI_RS10780
uniprot id: B0ST45
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS04150
gene id: 456481:LEPBI_RS04150
uniprot id: B0SLS1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

456481:LEPBI RS14810
gene id: 456481:LEPBI_RS14810
uniprot id: B0SPI5
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS06350
gene id: 456481:LEPBI_RS06350
uniprot id: B0SP83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

456481:LEPBI RS11945
gene id: 456481:LEPBI_RS11945
uniprot id: B0SL16
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS04905
gene id: 456481:LEPBI_RS04905
uniprot id: B0SMH8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

456481:LEPBI RS14130
gene id: 456481:LEPBI_RS14130
uniprot id: B0SNU1
names: Similarity
messages: Belongs to the AHA1 family.

456481:LEPBI RS06960
gene id: 456481:LEPBI_RS06960
uniprot id: B0SPW1
names: Similarity
messages: Belongs to the glutamine synthetase family.

456481:LEPBI RS09740
gene id: 456481:LEPBI_RS09740
uniprot id: B0SSI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

456481:LEPBI RS03645
gene id: 456481:LEPBI_RS03645
uniprot id: B0SL64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

456481:LEPBI RS01100
gene id: 456481:LEPBI_RS01100
uniprot id: B0SKD0
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS07265
gene id: 456481:LEPBI_RS07265
uniprot id: B0SQC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

456481:LEPBI RS00925
gene id: 456481:LEPBI_RS00925
uniprot id: B0SK86
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS14560
gene id: 456481:LEPBI_RS14560
uniprot id: B0SP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS07965
gene id: 456481:LEPBI_RS07965
uniprot id: B0SR20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS16945
gene id: 456481:LEPBI_RS16945
uniprot id: B0SRY3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

456481:LEPBI RS08925
gene id: 456481:LEPBI_RS08925
uniprot id: B0SS22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS01030
gene id: 456481:LEPBI_RS01030
uniprot id: B0SKA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS15395
gene id: 456481:LEPBI_RS15395
uniprot id: B0SQ57
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

456481:LEPBI RS12570
gene id: 456481:LEPBI_RS12570
uniprot id: B0SM05
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Membrane

456481:LEPBI RS11695
gene id: 456481:LEPBI_RS11695
uniprot id: B0SKW6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

456481:LEPBI RS12000
gene id: 456481:LEPBI_RS12000
uniprot id: B0SL26
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

456481:LEPBI RS06860
gene id: 456481:LEPBI_RS06860
uniprot id: B0SPU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

456481:LEPBI RS05610
gene id: 456481:LEPBI_RS05610
uniprot id: B0SN74
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

456481:LEPBI RS03060
gene id: 456481:LEPBI_RS03060
uniprot id: B0SKK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS03950
gene id: 456481:LEPBI_RS03950
uniprot id: B0SLC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

456481:LEPBI RS09705
gene id: 456481:LEPBI_RS09705
uniprot id: B0SSH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

456481:LEPBI RS11200
gene id: 456481:LEPBI_RS11200
uniprot id: B0STC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS05940
gene id: 456481:LEPBI_RS05940
uniprot id: B0SNP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

456481:LEPBI RS07515
gene id: 456481:LEPBI_RS07515
uniprot id: B0SQH6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

456481:LEPBI RS09480
gene id: 456481:LEPBI_RS09480
uniprot id: B0SSD3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

456481:LEPBI RS18315
gene id: 456481:LEPBI_RS18315
uniprot id: B0SUA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS15010
gene id: 456481:LEPBI_RS15010
uniprot id: B0SPM6
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

456481:LEPBI RS12685
gene id: 456481:LEPBI_RS12685
uniprot id: B0SM28
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS04625
gene id: 456481:LEPBI_RS04625
uniprot id: B0SMC3
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

456481:LEPBI RS04295
gene id: 456481:LEPBI_RS04295
uniprot id: B0SLV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

456481:LEPBI RS13010
gene id: 456481:LEPBI_RS13010
uniprot id: B0SM94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

456481:LEPBI RS06525
gene id: 456481:LEPBI_RS06525
uniprot id: B0SPB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

456481:LEPBI RS09020
gene id: 456481:LEPBI_RS09020
uniprot id: B0SS41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

456481:LEPBI RS00440
gene id: 456481:LEPBI_RS00440
uniprot id: B0SJR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

456481:LEPBI RS02715
gene id: 456481:LEPBI_RS02715
uniprot id: B0SJC8
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

456481:LEPBI RS03195
gene id: 456481:LEPBI_RS03195
uniprot id: B0SKM5
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS08275
gene id: 456481:LEPBI_RS08275
uniprot id: B0SR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

456481:LEPBI RS09935
gene id: 456481:LEPBI_RS09935
uniprot id: B0SSM4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

456481:LEPBI RS07310
gene id: 456481:LEPBI_RS07310
uniprot id: B0SQD7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

456481:LEPBI RS06395
gene id: 456481:LEPBI_RS06395
uniprot id: B0SP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

456481:LEPBI RS02220
gene id: 456481:LEPBI_RS02220
uniprot id: B0SJM2
names: Similarity
messages: Belongs to the peptidase S49 family.

456481:LEPBI RS08060
gene id: 456481:LEPBI_RS08060
uniprot id: B0SR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

456481:LEPBI RS18100
gene id: 456481:LEPBI_RS18100
uniprot id: B0SU60
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS04705
gene id: 456481:LEPBI_RS04705
uniprot id: B0SMD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS08545
gene id: 456481:LEPBI_RS08545
uniprot id: B0SRP1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

456481:LEPBI RS07925
gene id: 456481:LEPBI_RS07925
uniprot id: B0SR12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

456481:LEPBI RS07790
gene id: 456481:LEPBI_RS07790
uniprot id: B0SQY5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

456481:LEPBI RS18295
gene id: 456481:LEPBI_RS18295
uniprot id: B0SUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

456481:LEPBI RS12540
gene id: 456481:LEPBI_RS12540
uniprot id: B0SLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

456481:LEPBI RS11845
gene id: 456481:LEPBI_RS11845
uniprot id: B0SKZ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

456481:LEPBI RS03655
gene id: 456481:LEPBI_RS03655
uniprot id: B0SL66
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

456481:LEPBI RS06225
gene id: 456481:LEPBI_RS06225
uniprot id: B0SP59
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

456481:LEPBI RS04440
gene id: 456481:LEPBI_RS04440
uniprot id: B0SLX8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS00050
gene id: 456481:LEPBI_RS00050
uniprot id: B0SK37
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

456481:LEPBI RS05720
gene id: 456481:LEPBI_RS05720
uniprot id: B0SNK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

456481:LEPBI RS08345
gene id: 456481:LEPBI_RS08345
uniprot id: B0SRK0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

456481:LEPBI RS12085
gene id: 456481:LEPBI_RS12085
uniprot id: B0SLF2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

456481:LEPBI RS07565
gene id: 456481:LEPBI_RS07565
uniprot id: B0SQI6
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS01575
gene id: 456481:LEPBI_RS01575
uniprot id: B0SJL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

456481:LEPBI RS12255
gene id: 456481:LEPBI_RS12255
uniprot id: B0SLI6
names: Similarity
messages: Belongs to the neutral ceramidase family.

456481:LEPBI RS03235
gene id: 456481:LEPBI_RS03235
uniprot id: B0SKN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

456481:LEPBI RS00180
gene id: 456481:LEPBI_RS00180
uniprot id: B0SK62
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

456481:LEPBI RS06385
gene id: 456481:LEPBI_RS06385
uniprot id: B0SP90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

456481:LEPBI RS17445
gene id: 456481:LEPBI_RS17445
uniprot id: B0STS8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

456481:LEPBI RS09100
gene id: 456481:LEPBI_RS09100
uniprot id: B0SS57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

456481:LEPBI RS00975
gene id: 456481:LEPBI_RS00975
uniprot id: B0SK96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

456481:LEPBI RS12950
gene id: 456481:LEPBI_RS12950
uniprot id: B0SM82
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

456481:LEPBI RS16860
gene id: 456481:LEPBI_RS16860
uniprot id: B0SRW7
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS04505
gene id: 456481:LEPBI_RS04505
uniprot id: B0SLZ1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

456481:LEPBI RS06785
gene id: 456481:LEPBI_RS06785
uniprot id: B0SPS7
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS08850
gene id: 456481:LEPBI_RS08850
uniprot id: B0SS07
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

456481:LEPBI RS03400
gene id: 456481:LEPBI_RS03400
uniprot id: B0SKR6
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS08005
gene id: 456481:LEPBI_RS08005
uniprot id: B0SR27
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

456481:LEPBI RS07775
gene id: 456481:LEPBI_RS07775
uniprot id: B0SQY2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

456481:LEPBI RS13335
gene id: 456481:LEPBI_RS13335
uniprot id: B0SMR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

456481:LEPBI RS07340
gene id: 456481:LEPBI_RS07340
uniprot id: B0SQE3
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS03890
gene id: 456481:LEPBI_RS03890
uniprot id: B0SLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

456481:LEPBI RS18290
gene id: 456481:LEPBI_RS18290
uniprot id: B0SUA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

456481:LEPBI RS18410
gene id: 456481:LEPBI_RS18410
uniprot id: B0SUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS04175
gene id: 456481:LEPBI_RS04175
uniprot id: B0SLS6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

456481:LEPBI RS17100
gene id: 456481:LEPBI_RS17100
uniprot id: B0STK9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

456481:LEPBI RS14310
gene id: 456481:LEPBI_RS14310
uniprot id: B0SNX6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

456481:LEPBI RS10495
gene id: 456481:LEPBI_RS10495
uniprot id: B0SSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

456481:LEPBI RS13150
gene id: 456481:LEPBI_RS13150
uniprot id: B0SMM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

456481:LEPBI RS09650
gene id: 456481:LEPBI_RS09650
uniprot id: B0SSG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

456481:LEPBI RS14345
gene id: 456481:LEPBI_RS14345
uniprot id: B0SNY3
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

456481:LEPBI RS04785
gene id: 456481:LEPBI_RS04785
uniprot id: B0SMF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

456481:LEPBI RS14540
gene id: 456481:LEPBI_RS14540
uniprot id: B0SP24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

456481:LEPBI RS12530
gene id: 456481:LEPBI_RS12530
uniprot id: B0SLZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

456481:LEPBI RS11330
gene id: 456481:LEPBI_RS11330
uniprot id: B0STF1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

456481:LEPBI RS00435
gene id: 456481:LEPBI_RS00435
uniprot id: B0SJR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

456481:LEPBI RS12550
gene id: 456481:LEPBI_RS12550
uniprot id: B0SM01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

456481:LEPBI RS13620
gene id: 456481:LEPBI_RS13620
uniprot id: B0SN80
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

456481:LEPBI RS11450
gene id: 456481:LEPBI_RS11450
uniprot id: B0STH1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

456481:LEPBI RS15175
gene id: 456481:LEPBI_RS15175
uniprot id: B0SQ14
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

456481:LEPBI RS13445
gene id: 456481:LEPBI_RS13445
uniprot id: B0SMT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

456481:LEPBI RS17600
gene id: 456481:LEPBI_RS17600
uniprot id: B0STV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

456481:LEPBI RS12875
gene id: 456481:LEPBI_RS12875
uniprot id: B0SM66
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

456481:LEPBI RS09905
gene id: 456481:LEPBI_RS09905
uniprot id: B0SSL7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

456481:LEPBI RS07855
gene id: 456481:LEPBI_RS07855
uniprot id: B0SQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

456481:LEPBI RS18400
gene id: 456481:LEPBI_RS18400
uniprot id: B0SUC4
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

456481:LEPBI RS04910
gene id: 456481:LEPBI_RS04910
uniprot id: B0SMH9
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS09410
gene id: 456481:LEPBI_RS09410
uniprot id: B0SSB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS16425
gene id: 456481:LEPBI_RS16425
uniprot id: B0SRC4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS05805
gene id: 456481:LEPBI_RS05805
uniprot id: B0SNL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

456481:LEPBI RS13135
gene id: 456481:LEPBI_RS13135
uniprot id: B0SMM5
names: Subcellular Location Annotation
messages: Periplasmic flagellum

456481:LEPBI RS14665
gene id: 456481:LEPBI_RS14665
uniprot id: B0SPF6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

456481:LEPBI RS08150
gene id: 456481:LEPBI_RS08150
uniprot id: B0SR56
names: Similarity
messages: Belongs to the sigma-54 factor family.

456481:LEPBI RS12525
gene id: 456481:LEPBI_RS12525
uniprot id: B0SLP0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

456481:LEPBI RS05010
gene id: 456481:LEPBI_RS05010
uniprot id: B0SMJ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

456481:LEPBI RS00085
gene id: 456481:LEPBI_RS00085
uniprot id: B0SK44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

456481:LEPBI RS01040
gene id: 456481:LEPBI_RS01040
uniprot id: B0SKB3
names: Similarity
messages: Belongs to the AHA1 family.

456481:LEPBI RS16715
gene id: 456481:LEPBI_RS16715
uniprot id: B0SRI2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS08505
gene id: 456481:LEPBI_RS08505
uniprot id: B0SRN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS03395
gene id: 456481:LEPBI_RS03395
uniprot id: B0SKR5
names: Similarity
messages: Belongs to the DprA/Smf family.

456481:LEPBI RS17640
gene id: 456481:LEPBI_RS17640
uniprot id: B0STW6
names: Similarity
messages: Belongs to the AHA1 family.

456481:LEPBI RS05590
gene id: 456481:LEPBI_RS05590
uniprot id: B0SN70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

456481:LEPBI RS17390
gene id: 456481:LEPBI_RS17390
uniprot id: B0STR8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

456481:LEPBI RS01495
gene id: 456481:LEPBI_RS01495
uniprot id: B0SJF2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

456481:LEPBI RS09450
gene id: 456481:LEPBI_RS09450
uniprot id: B0SSC7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

456481:LEPBI RS17920
gene id: 456481:LEPBI_RS17920
uniprot id: B0SU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

456481:LEPBI RS12720
gene id: 456481:LEPBI_RS12720
uniprot id: B0SM35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

456481:LEPBI RS16040
gene id: 456481:LEPBI_RS16040
uniprot id: B0SQU3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

456481:LEPBI RS00360
gene id: 456481:LEPBI_RS00360
uniprot id: B0SJQ5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

456481:LEPBI RS12835
gene id: 456481:LEPBI_RS12835
uniprot id: B0SM58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS04610
gene id: 456481:LEPBI_RS04610
uniprot id: B0SMC0
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

456481:LEPBI RS15170
gene id: 456481:LEPBI_RS15170
uniprot id: B0SQ13
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

456481:LEPBI RS11650
gene id: 456481:LEPBI_RS11650
uniprot id: B0SKV7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

456481:LEPBI RS01205
gene id: 456481:LEPBI_RS01205
uniprot id: B0SKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-binding monooxygenase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

456481:LEPBI RS06850
gene id: 456481:LEPBI_RS06850
uniprot id: B0SPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

456481:LEPBI RS01305
gene id: 456481:LEPBI_RS01305
uniprot id: B0STJ7
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS00990
gene id: 456481:LEPBI_RS00990
uniprot id: B0SK99
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

456481:LEPBI RS18025
gene id: 456481:LEPBI_RS18025
uniprot id: B0SU45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

456481:LEPBI RS11915
gene id: 456481:LEPBI_RS11915
uniprot id: B0SL10
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

456481:LEPBI RS17810
gene id: 456481:LEPBI_RS17810
uniprot id: B0SU01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

456481:LEPBI RS14405
gene id: 456481:LEPBI_RS14405
uniprot id: B0SNZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

456481:LEPBI RS12310
gene id: 456481:LEPBI_RS12310
uniprot id: B0SLJ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

456481:LEPBI RS10060
gene id: 456481:LEPBI_RS10060
uniprot id: B0SSP9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

456481:LEPBI RS07885
gene id: 456481:LEPBI_RS07885
uniprot id: B0SR04
names: Similarity
messages: Belongs to the AAA ATPase family.

456481:LEPBI RS06845
gene id: 456481:LEPBI_RS06845
uniprot id: B0SPT9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

456481:LEPBI RS12865
gene id: 456481:LEPBI_RS12865
uniprot id: B0SM64
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS11640
gene id: 456481:LEPBI_RS11640
uniprot id: B0SKV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

456481:LEPBI RS10350
gene id: 456481:LEPBI_RS10350
uniprot id: B0SSV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS07945
gene id: 456481:LEPBI_RS07945
uniprot id: B0SR16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

456481:LEPBI RS08550
gene id: 456481:LEPBI_RS08550
uniprot id: B0SRP2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

456481:LEPBI RS12815
gene id: 456481:LEPBI_RS12815
uniprot id: B0SM54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

456481:LEPBI RS03535
gene id: 456481:LEPBI_RS03535
uniprot id: B0SL42
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS00185
gene id: 456481:LEPBI_RS00185
uniprot id: B0SK63
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS10315
gene id: 456481:LEPBI_RS10315
uniprot id: B0SSV0
names: Similarity
messages: Belongs to the CinA family.

456481:LEPBI RS05550
gene id: 456481:LEPBI_RS05550
uniprot id: B0SN63
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

456481:LEPBI RS04820
gene id: 456481:LEPBI_RS04820
uniprot id: B0SMG1
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS16815
gene id: 456481:LEPBI_RS16815
uniprot id: B0SRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

456481:LEPBI RS03900
gene id: 456481:LEPBI_RS03900
uniprot id: B0SLB5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

456481:LEPBI RS16770
gene id: 456481:LEPBI_RS16770
uniprot id: B0SRU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

456481:LEPBI RS00230
gene id: 456481:LEPBI_RS00230
uniprot id: B0SK47
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

456481:LEPBI RS01225
gene id: 456481:LEPBI_RS01225
uniprot id: B0SKG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

456481:LEPBI RS02695
gene id: 456481:LEPBI_RS02695
uniprot id: B0SJC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

456481:LEPBI RS05375
gene id: 456481:LEPBI_RS05375
uniprot id: B0SN28
names: Similarity
messages: Belongs to the AHA1 family.

456481:LEPBI RS14805
gene id: 456481:LEPBI_RS14805
uniprot id: B0SPI4
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

456481:LEPBI RS13380
gene id: 456481:LEPBI_RS13380
uniprot id: B0SMS5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS09635
gene id: 456481:LEPBI_RS09635
uniprot id: B0SSG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

456481:LEPBI RS06465
gene id: 456481:LEPBI_RS06465
uniprot id: B0SPA6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

456481:LEPBI RS03290
gene id: 456481:LEPBI_RS03290
uniprot id: B0SKP4
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS13350
gene id: 456481:LEPBI_RS13350
uniprot id: B0SMR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

456481:LEPBI RS13570
gene id: 456481:LEPBI_RS13570
uniprot id: B0SMW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

456481:LEPBI RS05750
gene id: 456481:LEPBI_RS05750
uniprot id: B0SNK7
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

456481:LEPBI RS03965
gene id: 456481:LEPBI_RS03965
uniprot id: B0SLC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

456481:LEPBI RS09210
gene id: 456481:LEPBI_RS09210
uniprot id: B0SS79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

456481:LEPBI RS00265
gene id: 456481:LEPBI_RS00265
uniprot id: B0SJN6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

456481:LEPBI RS06895
gene id: 456481:LEPBI_RS06895
uniprot id: B0SPU9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

456481:LEPBI RS16500
gene id: 456481:LEPBI_RS16500
uniprot id: B0SRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

456481:LEPBI RS11495
gene id: 456481:LEPBI_RS11495
uniprot id: B0STH9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

456481:LEPBI RS09595
gene id: 456481:LEPBI_RS09595
uniprot id: B0SSF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

456481:LEPBI RS08695
gene id: 456481:LEPBI_RS08695
uniprot id: B0SRS1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

456481:LEPBI RS17060
gene id: 456481:LEPBI_RS17060
uniprot id: B0SS01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

456481:LEPBI RS00535
gene id: 456481:LEPBI_RS00535
uniprot id: B0SJU0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

456481:LEPBI RS08730
gene id: 456481:LEPBI_RS08730
uniprot id: B0SRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

456481:LEPBI RS17880
gene id: 456481:LEPBI_RS17880
uniprot id: B0SU15
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS12295
gene id: 456481:LEPBI_RS12295
uniprot id: B0SLJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

456481:LEPBI RS06340
gene id: 456481:LEPBI_RS06340
uniprot id: B0SP81
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

456481:LEPBI RS09700
gene id: 456481:LEPBI_RS09700
uniprot id: B0SSH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

456481:LEPBI RS07500
gene id: 456481:LEPBI_RS07500
uniprot id: B0SQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

456481:LEPBI RS06805
gene id: 456481:LEPBI_RS06805
uniprot id: B0SPT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

456481:LEPBI RS13545
gene id: 456481:LEPBI_RS13545
uniprot id: B0SMV9
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS05885
gene id: 456481:LEPBI_RS05885
uniprot id: B0SNN4
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS03180
gene id: 456481:LEPBI_RS03180
uniprot id: B0SKM2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

456481:LEPBI RS01445
gene id: 456481:LEPBI_RS01445
uniprot id: B0SJ17
names: Similarity
messages: Belongs to the DAPG/phloretin hydrolase family.

456481:LEPBI RS07240
gene id: 456481:LEPBI_RS07240
uniprot id: B0SQC3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

456481:LEPBI RS16660
gene id: 456481:LEPBI_RS16660
uniprot id: B0SRH1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

456481:LEPBI RS09710
gene id: 456481:LEPBI_RS09710
uniprot id: B0SSH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

456481:LEPBI RS11360
gene id: 456481:LEPBI_RS11360
uniprot id: B0STF7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

456481:LEPBI RS09010
gene id: 456481:LEPBI_RS09010
uniprot id: B0SS39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

456481:LEPBI RS14420
gene id: 456481:LEPBI_RS14420
uniprot id: B0SNZ8
names: Similarity
messages: Belongs to the hemerythrin family.

456481:LEPBI RS02760
gene id: 456481:LEPBI_RS02760
uniprot id: B0SJA9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

456481:LEPBI RS17300
gene id: 456481:LEPBI_RS17300
uniprot id: B0STQ0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

456481:LEPBI RS16475
gene id: 456481:LEPBI_RS16475
uniprot id: B0SRD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

456481:LEPBI RS01515
gene id: 456481:LEPBI_RS01515
uniprot id: B0SJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

456481:LEPBI RS02260
gene id: 456481:LEPBI_RS02260
uniprot id: B0SJ33
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

456481:LEPBI RS10255
gene id: 456481:LEPBI_RS10255
uniprot id: B0SST8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

456481:LEPBI RS15610
gene id: 456481:LEPBI_RS15610
uniprot id: B0SQA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

456481:LEPBI RS13040
gene id: 456481:LEPBI_RS13040
uniprot id: B0SMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

456481:LEPBI RS01950
gene id: 456481:LEPBI_RS01950
uniprot id: B0SJI9
names: Similarity
messages: Belongs to the AHA1 family.

456481:LEPBI RS13555
gene id: 456481:LEPBI_RS13555
uniprot id: B0SMW1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

456481:LEPBI RS07200
gene id: 456481:LEPBI_RS07200
uniprot id: B0SQ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

456481:LEPBI RS07245
gene id: 456481:LEPBI_RS07245
uniprot id: B0SQC4
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS06370
gene id: 456481:LEPBI_RS06370
uniprot id: B0SP87
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

456481:LEPBI RS00885
gene id: 456481:LEPBI_RS00885
uniprot id: B0SK89
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

456481:LEPBI RS13235
gene id: 456481:LEPBI_RS13235
uniprot id: B0SMP5
names: Similarity
messages: Belongs to the citrate synthase family.

456481:LEPBI RS08025
gene id: 456481:LEPBI_RS08025
uniprot id: B0SR31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

456481:LEPBI RS03625
gene id: 456481:LEPBI_RS03625
uniprot id: B0SL60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

456481:LEPBI RS02850
gene id: 456481:LEPBI_RS02850
uniprot id: B0SJ86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

456481:LEPBI RS16020
gene id: 456481:LEPBI_RS16020
uniprot id: B0SQT9
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS15385
gene id: 456481:LEPBI_RS15385
uniprot id: B0SQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

456481:LEPBI RS03915
gene id: 456481:LEPBI_RS03915
uniprot id: B0SLB8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

456481:LEPBI RS15275
gene id: 456481:LEPBI_RS15275
uniprot id: B0SQ34
names: Cofactor
names: PTM
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.

456481:LEPBI RS06020
gene id: 456481:LEPBI_RS06020
uniprot id: B0SNR2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

456481:LEPBI RS15735
gene id: 456481:LEPBI_RS15735
uniprot id: B0SQN1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

456481:LEPBI RS08965
gene id: 456481:LEPBI_RS08965
uniprot id: B0SS30
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS06825
gene id: 456481:LEPBI_RS06825
uniprot id: B0SPT5
names: Similarity
messages: Belongs to the UPF0234 family.

456481:LEPBI RS13210
gene id: 456481:LEPBI_RS13210
uniprot id: B0SMP0
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS05730
gene id: 456481:LEPBI_RS05730
uniprot id: B0SNK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS11860
gene id: 456481:LEPBI_RS11860
uniprot id: B0SKZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

456481:LEPBI RS00725
gene id: 456481:LEPBI_RS00725
uniprot id: B0SJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

456481:LEPBI RS02315
gene id: 456481:LEPBI_RS02315
uniprot id: B0SJ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

456481:LEPBI RS14735
gene id: 456481:LEPBI_RS14735
uniprot id: B0SPH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

456481:LEPBI RS12040
gene id: 456481:LEPBI_RS12040
uniprot id: B0SLE2
names: Subcellular Location Annotation
messages: Membrane

456481:LEPBI RS06505
gene id: 456481:LEPBI_RS06505
uniprot id: B0SPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm