452863:ACHL RS11190
gene id: 452863:ACHL_RS11190
uniprot id: B8HA91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

452863:ACHL RS07475
gene id: 452863:ACHL_RS07475
uniprot id: B8HGB2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS19705
gene id: 452863:ACHL_RS19705
uniprot id: B8H8Y7
names: Similarity
messages: Belongs to the ParB family.

452863:ACHL RS12795
gene id: 452863:ACHL_RS12795
uniprot id: B8HC82
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

452863:ACHL RS02280
gene id: 452863:ACHL_RS02280
uniprot id: B8HAJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

452863:ACHL RS18960
gene id: 452863:ACHL_RS18960
uniprot id: B8H7T2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS10215
gene id: 452863:ACHL_RS10215
uniprot id: B8H9D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

452863:ACHL RS02560
gene id: 452863:ACHL_RS02560
uniprot id: B8HAQ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452863:ACHL RS02135
gene id: 452863:ACHL_RS02135
uniprot id: B8HAH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS07245
gene id: 452863:ACHL_RS07245
uniprot id: B8HG67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

452863:ACHL RS16130
gene id: 452863:ACHL_RS16130
uniprot id: B8HFY0
names: Similarity
messages: Belongs to the malate synthase family.

452863:ACHL RS02545
gene id: 452863:ACHL_RS02545
uniprot id: B8HAQ1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

452863:ACHL RS19685
gene id: 452863:ACHL_RS19685
uniprot id: B8H8Y3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01435
gene id: 452863:ACHL_RS01435
uniprot id: B8H9Q6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13900
gene id: 452863:ACHL_RS13900
uniprot id: B8HD71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

452863:ACHL RS01010
gene id: 452863:ACHL_RS01010
uniprot id: B8H944
names: Similarity
messages: Belongs to the CsoR family.

452863:ACHL RS06445
gene id: 452863:ACHL_RS06445
uniprot id: B8HF08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

452863:ACHL RS23020
gene id: 452863:ACHL_RS23020
uniprot id: B8HJD9
names: Similarity
messages: Belongs to the ribF family.

452863:ACHL RS02740
gene id: 452863:ACHL_RS02740
uniprot id: B8HB66
names: Similarity
messages: Belongs to the UPF0045 family.

452863:ACHL RS19020
gene id: 452863:ACHL_RS19020
uniprot id: B8H7U4
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

452863:ACHL RS01260
gene id: 452863:ACHL_RS01260
uniprot id: B8H995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS19735
gene id: 452863:ACHL_RS19735
uniprot id: B8H8Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

452863:ACHL RS07555
gene id: 452863:ACHL_RS07555
uniprot id: B8HGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

452863:ACHL RS17930
gene id: 452863:ACHL_RS17930
uniprot id: B8H6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

452863:ACHL RS06590
gene id: 452863:ACHL_RS06590
uniprot id: B8HFG2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS15640
gene id: 452863:ACHL_RS15640
uniprot id: B8HFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS07570
gene id: 452863:ACHL_RS07570
uniprot id: B8HGD1
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

452863:ACHL RS17110
gene id: 452863:ACHL_RS17110
uniprot id: B8HH80
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS16485
gene id: 452863:ACHL_RS16485
uniprot id: B8HGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS21510
gene id: 452863:ACHL_RS21510
uniprot id: B8HIH3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

452863:ACHL RS14345
gene id: 452863:ACHL_RS14345
uniprot id: B8HDT6
names: Similarity
messages: Belongs to the AHA1 family.

452863:ACHL RS08020
gene id: 452863:ACHL_RS08020
uniprot id: B8HGZ0
names: Similarity
messages: Belongs to the glutamine synthetase family.

452863:ACHL RS12055
gene id: 452863:ACHL_RS12055
uniprot id: B8HB37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452863:ACHL RS11480
gene id: 452863:ACHL_RS11480
uniprot id: B8HAS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452863:ACHL RS14145
gene id: 452863:ACHL_RS14145
uniprot id: B8HDP7
names: Similarity
messages: Belongs to the CdaR family.

452863:ACHL RS02500
gene id: 452863:ACHL_RS02500
uniprot id: B8HAP2
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

452863:ACHL RS15190
gene id: 452863:ACHL_RS15190
uniprot id: B8HF16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

452863:ACHL RS18150
gene id: 452863:ACHL_RS18150
uniprot id: B8H6Q2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

452863:ACHL RS00010
gene id: 452863:ACHL_RS00010
uniprot id: B8H7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

452863:ACHL RS05860
gene id: 452863:ACHL_RS05860
uniprot id: B8HEP1
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS17165
gene id: 452863:ACHL_RS17165
uniprot id: B8HH91
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12760
gene id: 452863:ACHL_RS12760
uniprot id: B8HC75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

452863:ACHL RS13520
gene id: 452863:ACHL_RS13520
uniprot id: B8HCZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

452863:ACHL RS09275
gene id: 452863:ACHL_RS09275
uniprot id: B8H7N7
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS09895
gene id: 452863:ACHL_RS09895
uniprot id: B8H8R0
names: Similarity
messages: Belongs to the peptidase M13 family.

452863:ACHL RS23055
gene id: 452863:ACHL_RS23055
uniprot id: B8HJE6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452863:ACHL RS01740
gene id: 452863:ACHL_RS01740
uniprot id: B8H9W8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

452863:ACHL RS10315
gene id: 452863:ACHL_RS10315
uniprot id: B8H9F4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

452863:ACHL RS13015
gene id: 452863:ACHL_RS13015
uniprot id: B8HCC5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

452863:ACHL RS11215
gene id: 452863:ACHL_RS11215
uniprot id: B8HA96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

452863:ACHL RS05735
gene id: 452863:ACHL_RS05735
uniprot id: B8HE98
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

452863:ACHL RS09910
gene id: 452863:ACHL_RS09910
uniprot id: B8H8R3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11125
gene id: 452863:ACHL_RS11125
uniprot id: B8HA79
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

452863:ACHL RS10000
gene id: 452863:ACHL_RS10000
uniprot id: B8H8T1
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

452863:ACHL RS03995
gene id: 452863:ACHL_RS03995
uniprot id: B8HCL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

452863:ACHL RS07365
gene id: 452863:ACHL_RS07365
uniprot id: B8HG90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

452863:ACHL RS07700
gene id: 452863:ACHL_RS07700
uniprot id: B8HGF4
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS08240
gene id: 452863:ACHL_RS08240
uniprot id: B8HH34
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08420
gene id: 452863:ACHL_RS08420
uniprot id: B8HH63
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

452863:ACHL RS13185
gene id: 452863:ACHL_RS13185
uniprot id: B8HCF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

452863:ACHL RS16870
gene id: 452863:ACHL_RS16870
uniprot id: B8HGQ6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS01895
gene id: 452863:ACHL_RS01895
uniprot id: B8H9Z8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

452863:ACHL RS12660
gene id: 452863:ACHL_RS12660
uniprot id: B8HBT2
names: Similarity
messages: Belongs to the DEAD box helicase family.

452863:ACHL RS22920
gene id: 452863:ACHL_RS22920
uniprot id: B8HJB8
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

452863:ACHL RS12675
gene id: 452863:ACHL_RS12675
uniprot id: B8HBT5
names: Similarity
messages: Belongs to the peptidase M24B family.

452863:ACHL RS19610
gene id: 452863:ACHL_RS19610
uniprot id: B8H8W7
names: Similarity
messages: Belongs to the peptidase M18 family.

452863:ACHL RS08515
gene id: 452863:ACHL_RS08515
uniprot id: B8H6U9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

452863:ACHL RS11450
gene id: 452863:ACHL_RS11450
uniprot id: B8HAE0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

452863:ACHL RS23205
gene id: 452863:ACHL_RS23205
uniprot id: B8HJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS05545
gene id: 452863:ACHL_RS05545
uniprot id: B8HE61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS02185
gene id: 452863:ACHL_RS02185
uniprot id: B8HAI0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

452863:ACHL RS12180
gene id: 452863:ACHL_RS12180
uniprot id: B8HBI8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

452863:ACHL RS18285
gene id: 452863:ACHL_RS18285
uniprot id: B8H6S9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS19785
gene id: 452863:ACHL_RS19785
uniprot id: B8HHJ9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

452863:ACHL RS08900
gene id: 452863:ACHL_RS08900
uniprot id: B8H7G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS04640
gene id: 452863:ACHL_RS04640
uniprot id: B8HDA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

452863:ACHL RS00205
gene id: 452863:ACHL_RS00205
uniprot id: B8H867
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

452863:ACHL RS13430
gene id: 452863:ACHL_RS13430
uniprot id: B8HCX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

452863:ACHL RS11475
gene id: 452863:ACHL_RS11475
uniprot id: B8HAS3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS09345
gene id: 452863:ACHL_RS09345
uniprot id: B8H7Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

452863:ACHL RS12695
gene id: 452863:ACHL_RS12695
uniprot id: B8HBT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

452863:ACHL RS17935
gene id: 452863:ACHL_RS17935
uniprot id: B8H6K9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12995
gene id: 452863:ACHL_RS12995
uniprot id: B8HCC1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

452863:ACHL RS02315
gene id: 452863:ACHL_RS02315
uniprot id: B8HAK6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS14790
gene id: 452863:ACHL_RS14790
uniprot id: B8HEE9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08460
gene id: 452863:ACHL_RS08460
uniprot id: B8H6T9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

452863:ACHL RS20275
gene id: 452863:ACHL_RS20275
uniprot id: B8HHR9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

452863:ACHL RS21935
gene id: 452863:ACHL_RS21935
uniprot id: B8HIQ9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

452863:ACHL RS10055
gene id: 452863:ACHL_RS10055
uniprot id: B8H8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

452863:ACHL RS13510
gene id: 452863:ACHL_RS13510
uniprot id: B8HCZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

452863:ACHL RS02320
gene id: 452863:ACHL_RS02320
uniprot id: B8HAK7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452863:ACHL RS18325
gene id: 452863:ACHL_RS18325
uniprot id: B8H711
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS05950
gene id: 452863:ACHL_RS05950
uniprot id: B8HER0
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08945
gene id: 452863:ACHL_RS08945
uniprot id: B8H7H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

452863:ACHL RS23405
gene id: 452863:ACHL_RS23405
uniprot id: B8HDX8
names: Similarity
messages: Belongs to the peptidase S8 family.

452863:ACHL RS10190
gene id: 452863:ACHL_RS10190
uniprot id: B8H9C8
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

452863:ACHL RS08530
gene id: 452863:ACHL_RS08530
uniprot id: B8H6V2
names: Similarity
messages: Belongs to the glutamate synthase family.

452863:ACHL RS14040
gene id: 452863:ACHL_RS14040
uniprot id: B8HDM6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane

452863:ACHL RS14250
gene id: 452863:ACHL_RS14250
uniprot id: B8HDR7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

452863:ACHL RS14210
gene id: 452863:ACHL_RS14210
uniprot id: B8HDQ9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

452863:ACHL RS18550
gene id: 452863:ACHL_RS18550
uniprot id: B8H757
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

452863:ACHL RS15010
gene id: 452863:ACHL_RS15010
uniprot id: B8HEK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS05745
gene id: 452863:ACHL_RS05745
uniprot id: B8HE99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

452863:ACHL RS08055
gene id: 452863:ACHL_RS08055
uniprot id: B8HGZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

452863:ACHL RS17360
gene id: 452863:ACHL_RS17360
uniprot id: B8HHD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

452863:ACHL RS20925
gene id: 452863:ACHL_RS20925
uniprot id: B8HI53
names: Similarity
messages: Belongs to the GSP E family.

452863:ACHL RS01080
gene id: 452863:ACHL_RS01080
uniprot id: B8H958
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS10110
gene id: 452863:ACHL_RS10110
uniprot id: B8H8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

452863:ACHL RS15715
gene id: 452863:ACHL_RS15715
uniprot id: B8HFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS08590
gene id: 452863:ACHL_RS08590
uniprot id: B8H6W2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

452863:ACHL RS09190
gene id: 452863:ACHL_RS09190
uniprot id: B8H7M0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

452863:ACHL RS17830
gene id: 452863:ACHL_RS17830
uniprot id: B8H6I9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

452863:ACHL RS18940
gene id: 452863:ACHL_RS18940
uniprot id: B8H7S8
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11160
gene id: 452863:ACHL_RS11160
uniprot id: B8HA86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

452863:ACHL RS14925
gene id: 452863:ACHL_RS14925
uniprot id: B8HEI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

452863:ACHL RS08040
gene id: 452863:ACHL_RS08040
uniprot id: B8HGZ4
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06790
gene id: 452863:ACHL_RS06790
uniprot id: B8HFK1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

452863:ACHL RS00665
gene id: 452863:ACHL_RS00665
uniprot id: B8H8G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

452863:ACHL RS01335
gene id: 452863:ACHL_RS01335
uniprot id: B8H9B0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS16195
gene id: 452863:ACHL_RS16195
uniprot id: B8HFZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

452863:ACHL RS08770
gene id: 452863:ACHL_RS08770
uniprot id: B8H6Z7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS03280
gene id: 452863:ACHL_RS03280
uniprot id: B8HBG9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

452863:ACHL RS01910
gene id: 452863:ACHL_RS01910
uniprot id: B8HA01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

452863:ACHL RS00040
gene id: 452863:ACHL_RS00040
uniprot id: B8H7D4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS18670
gene id: 452863:ACHL_RS18670
uniprot id: B8H775
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

452863:ACHL RS13245
gene id: 452863:ACHL_RS13245
uniprot id: B8HCH0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS05265
gene id: 452863:ACHL_RS05265
uniprot id: B8HE04
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12390
gene id: 452863:ACHL_RS12390
uniprot id: B8HBN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS10040
gene id: 452863:ACHL_RS10040
uniprot id: B8H8T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS10285
gene id: 452863:ACHL_RS10285
uniprot id: B8H9E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS06315
gene id: 452863:ACHL_RS06315
uniprot id: B8HEY2
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

452863:ACHL RS08710
gene id: 452863:ACHL_RS08710
uniprot id: B8H6Y4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

452863:ACHL RS09755
gene id: 452863:ACHL_RS09755
uniprot id: B8H8N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

452863:ACHL RS12425
gene id: 452863:ACHL_RS12425
uniprot id: B8HBN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS10290
gene id: 452863:ACHL_RS10290
uniprot id: B8H9E9
names: Similarity
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

452863:ACHL RS15260
gene id: 452863:ACHL_RS15260
uniprot id: B8HF30
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS14295
gene id: 452863:ACHL_RS14295
uniprot id: B8HDS6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

452863:ACHL RS09630
gene id: 452863:ACHL_RS09630
uniprot id: B8H8K7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

452863:ACHL RS15130
gene id: 452863:ACHL_RS15130
uniprot id: B8HEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

452863:ACHL RS17310
gene id: 452863:ACHL_RS17310
uniprot id: B8HHC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

452863:ACHL RS12930
gene id: 452863:ACHL_RS12930
uniprot id: B8HCA9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS08835
gene id: 452863:ACHL_RS08835
uniprot id: B8H7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS07635
gene id: 452863:ACHL_RS07635
uniprot id: B8HGE1
names: Similarity
messages: Belongs to the TlyA family.

452863:ACHL RS14395
gene id: 452863:ACHL_RS14395
uniprot id: B8HDU6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12970
gene id: 452863:ACHL_RS12970
uniprot id: B8HCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

452863:ACHL RS10455
gene id: 452863:ACHL_RS10455
uniprot id: B8H9H9
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS08520
gene id: 452863:ACHL_RS08520
uniprot id: B8H6V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

452863:ACHL RS08135
gene id: 452863:ACHL_RS08135
uniprot id: B8HH13
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

452863:ACHL RS06480
gene id: 452863:ACHL_RS06480
uniprot id: B8HFE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

452863:ACHL RS17635
gene id: 452863:ACHL_RS17635
uniprot id: B8HHI5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

452863:ACHL RS13515
gene id: 452863:ACHL_RS13515
uniprot id: B8HCZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

452863:ACHL RS03940
gene id: 452863:ACHL_RS03940
uniprot id: B8HCJ9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

452863:ACHL RS18800
gene id: 452863:ACHL_RS18800
uniprot id: B8H7A1
names: Similarity
messages: Belongs to the HSP15 family.

452863:ACHL RS13095
gene id: 452863:ACHL_RS13095
uniprot id: B8HCE1
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

452863:ACHL RS15240
gene id: 452863:ACHL_RS15240
uniprot id: B8HF26
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

452863:ACHL RS13300
gene id: 452863:ACHL_RS13300
uniprot id: B8HCI1
names: Similarity
messages: Belongs to the peptidase A24 family.

452863:ACHL RS04455
gene id: 452863:ACHL_RS04455
uniprot id: B8HCU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

452863:ACHL RS04265
gene id: 452863:ACHL_RS04265
uniprot id: B8HCR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

452863:ACHL RS18825
gene id: 452863:ACHL_RS18825
uniprot id: B8H7A6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

452863:ACHL RS02175
gene id: 452863:ACHL_RS02175
uniprot id: B8HAH8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

452863:ACHL RS13415
gene id: 452863:ACHL_RS13415
uniprot id: B8HCX4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

452863:ACHL RS10825
gene id: 452863:ACHL_RS10825
uniprot id: B8HA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

452863:ACHL RS04645
gene id: 452863:ACHL_RS04645
uniprot id: B8HDB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

452863:ACHL RS03840
gene id: 452863:ACHL_RS03840
uniprot id: B8HC52
names: Similarity
messages: Belongs to the cytochrome P450 family.

452863:ACHL RS19140
gene id: 452863:ACHL_RS19140
uniprot id: B8H7W6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

452863:ACHL RS06125
gene id: 452863:ACHL_RS06125
uniprot id: B8HEU5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

452863:ACHL RS18385
gene id: 452863:ACHL_RS18385
uniprot id: B8H723
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06375
gene id: 452863:ACHL_RS06375
uniprot id: B8HEZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

452863:ACHL RS12820
gene id: 452863:ACHL_RS12820
uniprot id: B8HC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS08430
gene id: 452863:ACHL_RS08430
uniprot id: B8HH65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

452863:ACHL RS17540
gene id: 452863:ACHL_RS17540
uniprot id: B8HHG6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS03615
gene id: 452863:ACHL_RS03615
uniprot id: B8HC10
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

452863:ACHL RS02470
gene id: 452863:ACHL_RS02470
uniprot id: B8HAN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS07670
gene id: 452863:ACHL_RS07670
uniprot id: B8HGE8
names: Subcellular Location Annotation
messages: Nucleus

452863:ACHL RS16855
gene id: 452863:ACHL_RS16855
uniprot id: B8HGQ3
names: Similarity
messages: Belongs to the PrpF family.

452863:ACHL RS10210
gene id: 452863:ACHL_RS10210
uniprot id: B8H9D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

452863:ACHL RS12050
gene id: 452863:ACHL_RS12050
uniprot id: B8HB36
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11270
gene id: 452863:ACHL_RS11270
uniprot id: B8HAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

452863:ACHL RS15075
gene id: 452863:ACHL_RS15075
uniprot id: B8HEL6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

452863:ACHL RS10050
gene id: 452863:ACHL_RS10050
uniprot id: B8H8U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

452863:ACHL RS09715
gene id: 452863:ACHL_RS09715
uniprot id: B8H8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

452863:ACHL RS01115
gene id: 452863:ACHL_RS01115
uniprot id: B8H965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

452863:ACHL RS01020
gene id: 452863:ACHL_RS01020
uniprot id: B8H946
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS03550
gene id: 452863:ACHL_RS03550
uniprot id: B8HBZ7
names: Similarity
messages: Belongs to the malate synthase family.

452863:ACHL RS10840
gene id: 452863:ACHL_RS10840
uniprot id: B8HA27
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

452863:ACHL RS08700
gene id: 452863:ACHL_RS08700
uniprot id: B8H6Y2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

452863:ACHL RS07185
gene id: 452863:ACHL_RS07185
uniprot id: B8HG55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

452863:ACHL RS03675
gene id: 452863:ACHL_RS03675
uniprot id: B8HC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS01680
gene id: 452863:ACHL_RS01680
uniprot id: B8H9V7
names: Similarity
messages: Belongs to the Nth/MutY family.

452863:ACHL RS06410
gene id: 452863:ACHL_RS06410
uniprot id: B8HF01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

452863:ACHL RS14335
gene id: 452863:ACHL_RS14335
uniprot id: B8HDT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

452863:ACHL RS10805
gene id: 452863:ACHL_RS10805
uniprot id: B8HA20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

452863:ACHL RS15300
gene id: 452863:ACHL_RS15300
uniprot id: B8HF39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

452863:ACHL RS13500
gene id: 452863:ACHL_RS13500
uniprot id: B8HCZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

452863:ACHL RS11555
gene id: 452863:ACHL_RS11555
uniprot id: B8HAT7
names: Similarity
messages: Belongs to the MQO family.

452863:ACHL RS11490
gene id: 452863:ACHL_RS11490
uniprot id: B8HAS6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13945
gene id: 452863:ACHL_RS13945
uniprot id: B8HD80
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

452863:ACHL RS12870
gene id: 452863:ACHL_RS12870
uniprot id: B8HC97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

452863:ACHL RS17995
gene id: 452863:ACHL_RS17995
uniprot id: B8H6M1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

452863:ACHL RS09710
gene id: 452863:ACHL_RS09710
uniprot id: B8H8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

452863:ACHL RS01885
gene id: 452863:ACHL_RS01885
uniprot id: B8H9Z6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

452863:ACHL RS13265
gene id: 452863:ACHL_RS13265
uniprot id: B8HCH4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

452863:ACHL RS05420
gene id: 452863:ACHL_RS05420
uniprot id: B8HE36
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

452863:ACHL RS15565
gene id: 452863:ACHL_RS15565
uniprot id: B8HF91
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

452863:ACHL RS06475
gene id: 452863:ACHL_RS06475
uniprot id: B8HFE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

452863:ACHL RS12600
gene id: 452863:ACHL_RS12600
uniprot id: B8HBS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

452863:ACHL RS06780
gene id: 452863:ACHL_RS06780
uniprot id: B8HFJ9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS16255
gene id: 452863:ACHL_RS16255
uniprot id: B8HG04
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS07885
gene id: 452863:ACHL_RS07885
uniprot id: B8HGW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

452863:ACHL RS05935
gene id: 452863:ACHL_RS05935
uniprot id: B8HEQ7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452863:ACHL RS07230
gene id: 452863:ACHL_RS07230
uniprot id: B8HG64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

452863:ACHL RS01775
gene id: 452863:ACHL_RS01775
uniprot id: B8H9X5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

452863:ACHL RS08775
gene id: 452863:ACHL_RS08775
uniprot id: B8H6Z8
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

452863:ACHL RS06335
gene id: 452863:ACHL_RS06335
uniprot id: B8HEY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

452863:ACHL RS13695
gene id: 452863:ACHL_RS13695
uniprot id: B8HD30
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS07465
gene id: 452863:ACHL_RS07465
uniprot id: B8HGB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

452863:ACHL RS13410
gene id: 452863:ACHL_RS13410
uniprot id: B8HCX3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

452863:ACHL RS00315
gene id: 452863:ACHL_RS00315
uniprot id: B8H890
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

452863:ACHL RS12070
gene id: 452863:ACHL_RS12070
uniprot id: B8HB40
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

452863:ACHL RS01285
gene id: 452863:ACHL_RS01285
uniprot id: B8H9A0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452863:ACHL RS16565
gene id: 452863:ACHL_RS16565
uniprot id: B8HGJ2
names: Similarity
messages: Belongs to the CdaR family.

452863:ACHL RS17495
gene id: 452863:ACHL_RS17495
uniprot id: B8HHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS03120
gene id: 452863:ACHL_RS03120
uniprot id: B8HBD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS13785
gene id: 452863:ACHL_RS13785
uniprot id: B8HD49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS12945
gene id: 452863:ACHL_RS12945
uniprot id: B8HCB2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12120
gene id: 452863:ACHL_RS12120
uniprot id: B8HBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

452863:ACHL RS22665
gene id: 452863:ACHL_RS22665
uniprot id: B8HJ64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

452863:ACHL RS18680
gene id: 452863:ACHL_RS18680
uniprot id: B8H777
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11680
gene id: 452863:ACHL_RS11680
uniprot id: B8HAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS10015
gene id: 452863:ACHL_RS10015
uniprot id: B8H8T4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

452863:ACHL RS11880
gene id: 452863:ACHL_RS11880
uniprot id: B8HB02
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

452863:ACHL RS09775
gene id: 452863:ACHL_RS09775
uniprot id: B8H8N6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

452863:ACHL RS01105
gene id: 452863:ACHL_RS01105
uniprot id: B8H963
names: Similarity
messages: Belongs to the peptidase S24 family.

452863:ACHL RS00730
gene id: 452863:ACHL_RS00730
uniprot id: B8H8H4
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12990
gene id: 452863:ACHL_RS12990
uniprot id: B8HCC0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

452863:ACHL RS04960
gene id: 452863:ACHL_RS04960
uniprot id: B8HDH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

452863:ACHL RS18140
gene id: 452863:ACHL_RS18140
uniprot id: B8H6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

452863:ACHL RS19615
gene id: 452863:ACHL_RS19615
uniprot id: B8H8W8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

452863:ACHL RS18335
gene id: 452863:ACHL_RS18335
uniprot id: B8H713
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

452863:ACHL RS19835
gene id: 452863:ACHL_RS19835
uniprot id: B8HHK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

452863:ACHL RS18045
gene id: 452863:ACHL_RS18045
uniprot id: B8H6N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS12310
gene id: 452863:ACHL_RS12310
uniprot id: B8HBL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

452863:ACHL RS09915
gene id: 452863:ACHL_RS09915
uniprot id: B8H8R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

452863:ACHL RS07565
gene id: 452863:ACHL_RS07565
uniprot id: B8HGD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

452863:ACHL RS13165
gene id: 452863:ACHL_RS13165
uniprot id: B8HCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

452863:ACHL RS18220
gene id: 452863:ACHL_RS18220
uniprot id: B8H6R6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08765
gene id: 452863:ACHL_RS08765
uniprot id: B8H6Z6
names: Similarity
messages: Belongs to the KdgT transporter family.

452863:ACHL RS09675
gene id: 452863:ACHL_RS09675
uniprot id: B8H8L6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

452863:ACHL RS10875
gene id: 452863:ACHL_RS10875
uniprot id: B8HA34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

452863:ACHL RS09745
gene id: 452863:ACHL_RS09745
uniprot id: B8H8N0
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS16765
gene id: 452863:ACHL_RS16765
uniprot id: B8HGN2
names: Similarity
messages: Belongs to the PrpF family.

452863:ACHL RS16430
gene id: 452863:ACHL_RS16430
uniprot id: B8HG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS07240
gene id: 452863:ACHL_RS07240
uniprot id: B8HG66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

452863:ACHL RS13435
gene id: 452863:ACHL_RS13435
uniprot id: B8HCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

452863:ACHL RS19300
gene id: 452863:ACHL_RS19300
uniprot id: B8H7Z8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

452863:ACHL RS07905
gene id: 452863:ACHL_RS07905
uniprot id: B8HGW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

452863:ACHL RS12005
gene id: 452863:ACHL_RS12005
uniprot id: B8HB27
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

452863:ACHL RS04850
gene id: 452863:ACHL_RS04850
uniprot id: B8HDF2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS07330
gene id: 452863:ACHL_RS07330
uniprot id: B8HG83
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

452863:ACHL RS21770
gene id: 452863:ACHL_RS21770
uniprot id: B8HIM5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

452863:ACHL RS10275
gene id: 452863:ACHL_RS10275
uniprot id: B8H9E6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452863:ACHL RS10855
gene id: 452863:ACHL_RS10855
uniprot id: B8HA30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452863:ACHL RS15110
gene id: 452863:ACHL_RS15110
uniprot id: B8HEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

452863:ACHL RS09995
gene id: 452863:ACHL_RS09995
uniprot id: B8H8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

452863:ACHL RS14990
gene id: 452863:ACHL_RS14990
uniprot id: B8HEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

452863:ACHL RS07540
gene id: 452863:ACHL_RS07540
uniprot id: B8HGC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

452863:ACHL RS14975
gene id: 452863:ACHL_RS14975
uniprot id: B8HEJ6
names: Similarity
messages: Belongs to the MotB family.

452863:ACHL RS06200
gene id: 452863:ACHL_RS06200
uniprot id: B8HEV9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

452863:ACHL RS09195
gene id: 452863:ACHL_RS09195
uniprot id: B8H7M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

452863:ACHL RS17000
gene id: 452863:ACHL_RS17000
uniprot id: B8HGT2
names: Similarity
messages: Belongs to the DapA family.

452863:ACHL RS04710
gene id: 452863:ACHL_RS04710
uniprot id: B8HDC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

452863:ACHL RS03230
gene id: 452863:ACHL_RS03230
uniprot id: B8HBF9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452863:ACHL RS04410
gene id: 452863:ACHL_RS04410
uniprot id: B8HCT5
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04525
gene id: 452863:ACHL_RS04525
uniprot id: B8HCV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

452863:ACHL RS08060
gene id: 452863:ACHL_RS08060
uniprot id: B8HGZ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

452863:ACHL RS14995
gene id: 452863:ACHL_RS14995
uniprot id: B8HEK0
names: Similarity
messages: Belongs to the FlgD family.

452863:ACHL RS15055
gene id: 452863:ACHL_RS15055
uniprot id: B8HEL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

452863:ACHL RS13665
gene id: 452863:ACHL_RS13665
uniprot id: B8HD25
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

452863:ACHL RS20915
gene id: 452863:ACHL_RS20915
uniprot id: B8HI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

452863:ACHL RS17925
gene id: 452863:ACHL_RS17925
uniprot id: B8H6K7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

452863:ACHL RS15815
gene id: 452863:ACHL_RS15815
uniprot id: B8HFR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

452863:ACHL RS01560
gene id: 452863:ACHL_RS01560
uniprot id: B8H9T1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

452863:ACHL RS11305
gene id: 452863:ACHL_RS11305
uniprot id: B8HAB3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

452863:ACHL RS10065
gene id: 452863:ACHL_RS10065
uniprot id: B8H8U4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

452863:ACHL RS11200
gene id: 452863:ACHL_RS11200
uniprot id: B8HA93
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

452863:ACHL RS19010
gene id: 452863:ACHL_RS19010
uniprot id: B8H7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

452863:ACHL RS02550
gene id: 452863:ACHL_RS02550
uniprot id: B8HAQ2
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

452863:ACHL RS13870
gene id: 452863:ACHL_RS13870
uniprot id: B8HD66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

452863:ACHL RS10005
gene id: 452863:ACHL_RS10005
uniprot id: B8H8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

452863:ACHL RS17465
gene id: 452863:ACHL_RS17465
uniprot id: B8HHF1
names: Similarity
messages: Belongs to the ComB family.

452863:ACHL RS17375
gene id: 452863:ACHL_RS17375
uniprot id: B8HHD3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12550
gene id: 452863:ACHL_RS12550
uniprot id: B8HBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS17220
gene id: 452863:ACHL_RS17220
uniprot id: B8HHA2
names: Similarity
messages: Belongs to the hyi family.

452863:ACHL RS04635
gene id: 452863:ACHL_RS04635
uniprot id: B8HDA8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

452863:ACHL RS00405
gene id: 452863:ACHL_RS00405
uniprot id: B8H8A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

452863:ACHL RS08435
gene id: 452863:ACHL_RS08435
uniprot id: B8H6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

452863:ACHL RS03960
gene id: 452863:ACHL_RS03960
uniprot id: B8HCK3
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

452863:ACHL RS08470
gene id: 452863:ACHL_RS08470
uniprot id: B8H6U1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

452863:ACHL RS14135
gene id: 452863:ACHL_RS14135
uniprot id: B8HDP5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

452863:ACHL RS10245
gene id: 452863:ACHL_RS10245
uniprot id: B8H9E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

452863:ACHL RS09520
gene id: 452863:ACHL_RS09520
uniprot id: B8H8I6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

452863:ACHL RS15910
gene id: 452863:ACHL_RS15910
uniprot id: B8HFT6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS02200
gene id: 452863:ACHL_RS02200
uniprot id: B8HAI3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS17490
gene id: 452863:ACHL_RS17490
uniprot id: B8HHF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS11090
gene id: 452863:ACHL_RS11090
uniprot id: B8HA73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

452863:ACHL RS10550
gene id: 452863:ACHL_RS10550
uniprot id: B8H9J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS11265
gene id: 452863:ACHL_RS11265
uniprot id: B8HAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS13950
gene id: 452863:ACHL_RS13950
uniprot id: B8HD81
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

452863:ACHL RS15695
gene id: 452863:ACHL_RS15695
uniprot id: B8HFB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

452863:ACHL RS07280
gene id: 452863:ACHL_RS07280
uniprot id: B8HG73
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

452863:ACHL RS02555
gene id: 452863:ACHL_RS02555
uniprot id: B8HAQ3
names: Similarity
messages: Belongs to the IucA/IucC family.

452863:ACHL RS02985
gene id: 452863:ACHL_RS02985
uniprot id: B8HBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

452863:ACHL RS14100
gene id: 452863:ACHL_RS14100
uniprot id: B8HDN8
names: Similarity
messages: Belongs to the type IB topoisomerase family.

452863:ACHL RS15945
gene id: 452863:ACHL_RS15945
uniprot id: B8HFU3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS14980
gene id: 452863:ACHL_RS14980
uniprot id: B8HEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

452863:ACHL RS06565
gene id: 452863:ACHL_RS06565
uniprot id: B8HFF7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

452863:ACHL RS07950
gene id: 452863:ACHL_RS07950
uniprot id: B8HGX5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

452863:ACHL RS10235
gene id: 452863:ACHL_RS10235
uniprot id: B8H9D8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

452863:ACHL RS06840
gene id: 452863:ACHL_RS06840
uniprot id: B8HFL1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

452863:ACHL RS13660
gene id: 452863:ACHL_RS13660
uniprot id: B8HD24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

452863:ACHL RS11505
gene id: 452863:ACHL_RS11505
uniprot id: B8HAS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

452863:ACHL RS22345
gene id: 452863:ACHL_RS22345
uniprot id: B8HIZ8
names: Similarity
messages: Belongs to the GSP E family.

452863:ACHL RS00020
gene id: 452863:ACHL_RS00020
uniprot id: B8H7D0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

452863:ACHL RS11795
gene id: 452863:ACHL_RS11795
uniprot id: B8HAY5
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS10945
gene id: 452863:ACHL_RS10945
uniprot id: B8HA46
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

452863:ACHL RS16375
gene id: 452863:ACHL_RS16375
uniprot id: B8HG26
names: Similarity
messages: Belongs to the asp23 family.

452863:ACHL RS02050
gene id: 452863:ACHL_RS02050
uniprot id: B8HAF3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

452863:ACHL RS11685
gene id: 452863:ACHL_RS11685
uniprot id: B8HAW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

452863:ACHL RS07590
gene id: 452863:ACHL_RS07590
uniprot id: B8HGD5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

452863:ACHL RS12710
gene id: 452863:ACHL_RS12710
uniprot id: B8HBU2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452863:ACHL RS00640
gene id: 452863:ACHL_RS00640
uniprot id: B8H8F5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452863:ACHL RS12010
gene id: 452863:ACHL_RS12010
uniprot id: B8HB28
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS03885
gene id: 452863:ACHL_RS03885
uniprot id: B8HC61
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13920
gene id: 452863:ACHL_RS13920
uniprot id: B8HD75
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06800
gene id: 452863:ACHL_RS06800
uniprot id: B8HFK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS18330
gene id: 452863:ACHL_RS18330
uniprot id: B8H712
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS09940
gene id: 452863:ACHL_RS09940
uniprot id: B8H8R9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

452863:ACHL RS19425
gene id: 452863:ACHL_RS19425
uniprot id: B8H823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

452863:ACHL RS11375
gene id: 452863:ACHL_RS11375
uniprot id: B8HAC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS11905
gene id: 452863:ACHL_RS11905
uniprot id: B8HB07
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

452863:ACHL RS09840
gene id: 452863:ACHL_RS09840
uniprot id: B8H8P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

452863:ACHL RS06105
gene id: 452863:ACHL_RS06105
uniprot id: B8HEU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS13580
gene id: 452863:ACHL_RS13580
uniprot id: B8HD07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

452863:ACHL RS15755
gene id: 452863:ACHL_RS15755
uniprot id: B8HFD0
names: Similarity
messages: Belongs to the DapA family.

452863:ACHL RS14085
gene id: 452863:ACHL_RS14085
uniprot id: B8HDN5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS13790
gene id: 452863:ACHL_RS13790
uniprot id: B8HD50
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

452863:ACHL RS13745
gene id: 452863:ACHL_RS13745
uniprot id: B8HD40
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Homodimer.

452863:ACHL RS18375
gene id: 452863:ACHL_RS18375
uniprot id: B8H721
names: Similarity
messages: Belongs to the AlaDH/PNT family.

452863:ACHL RS17345
gene id: 452863:ACHL_RS17345
uniprot id: B8HHC7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

452863:ACHL RS03160
gene id: 452863:ACHL_RS03160
uniprot id: B8HBE5
names: Similarity
messages: Belongs to the HIBADH-related family.

452863:ACHL RS11970
gene id: 452863:ACHL_RS11970
uniprot id: B8HB20
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS04430
gene id: 452863:ACHL_RS04430
uniprot id: B8HCT9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS00530
gene id: 452863:ACHL_RS00530
uniprot id: B8H8D3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS19520
gene id: 452863:ACHL_RS19520
uniprot id: B8H842
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

452863:ACHL RS13020
gene id: 452863:ACHL_RS13020
uniprot id: B8HCC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

452863:ACHL RS06870
gene id: 452863:ACHL_RS06870
uniprot id: B8HFL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS00320
gene id: 452863:ACHL_RS00320
uniprot id: B8H891
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12395
gene id: 452863:ACHL_RS12395
uniprot id: B8HBN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS14675
gene id: 452863:ACHL_RS14675
uniprot id: B8HEC6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

452863:ACHL RS03950
gene id: 452863:ACHL_RS03950
uniprot id: B8HCK1
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08455
gene id: 452863:ACHL_RS08455
uniprot id: B8H6T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

452863:ACHL RS02605
gene id: 452863:ACHL_RS02605
uniprot id: B8HAR3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

452863:ACHL RS22445
gene id: 452863:ACHL_RS22445
uniprot id: B8HJ19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

452863:ACHL RS10690
gene id: 452863:ACHL_RS10690
uniprot id: B8H9M2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS11320
gene id: 452863:ACHL_RS11320
uniprot id: B8HAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

452863:ACHL RS06905
gene id: 452863:ACHL_RS06905
uniprot id: B8HFM5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

452863:ACHL RS01355
gene id: 452863:ACHL_RS01355
uniprot id: B8H9B4
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS16670
gene id: 452863:ACHL_RS16670
uniprot id: B8HGL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

452863:ACHL RS15265
gene id: 452863:ACHL_RS15265
uniprot id: B8HF31
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

452863:ACHL RS04450
gene id: 452863:ACHL_RS04450
uniprot id: B8HCU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

452863:ACHL RS15790
gene id: 452863:ACHL_RS15790
uniprot id: B8HFD7
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06005
gene id: 452863:ACHL_RS06005
uniprot id: B8HES1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS01690
gene id: 452863:ACHL_RS01690
uniprot id: B8H9V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

452863:ACHL RS12880
gene id: 452863:ACHL_RS12880
uniprot id: B8HC99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

452863:ACHL RS18315
gene id: 452863:ACHL_RS18315
uniprot id: B8H709
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS05090
gene id: 452863:ACHL_RS05090
uniprot id: B8HDJ9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

452863:ACHL RS17660
gene id: 452863:ACHL_RS17660
uniprot id: B8HHJ0
names: Similarity
messages: Belongs to the glutamine synthetase family.

452863:ACHL RS16495
gene id: 452863:ACHL_RS16495
uniprot id: B8HGH7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

452863:ACHL RS22515
gene id: 452863:ACHL_RS22515
uniprot id: B8HJ33
names: Similarity
messages: Belongs to the toxin_10 family.

452863:ACHL RS12155
gene id: 452863:ACHL_RS12155
uniprot id: B8HBI3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS17910
gene id: 452863:ACHL_RS17910
uniprot id: B8H6K4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

452863:ACHL RS00025
gene id: 452863:ACHL_RS00025
uniprot id: B8H7D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

452863:ACHL RS19715
gene id: 452863:ACHL_RS19715
uniprot id: B8H8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

452863:ACHL RS22355
gene id: 452863:ACHL_RS22355
uniprot id: B8HJ00
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS14515
gene id: 452863:ACHL_RS14515
uniprot id: B8HDW9
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

452863:ACHL RS18340
gene id: 452863:ACHL_RS18340
uniprot id: B8H714
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS16655
gene id: 452863:ACHL_RS16655
uniprot id: B8HGL0
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

452863:ACHL RS04245
gene id: 452863:ACHL_RS04245
uniprot id: B8HCQ6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

452863:ACHL RS16150
gene id: 452863:ACHL_RS16150
uniprot id: B8HFY4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS07500
gene id: 452863:ACHL_RS07500
uniprot id: B8HGB7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

452863:ACHL RS07025
gene id: 452863:ACHL_RS07025
uniprot id: B8HFP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

452863:ACHL RS10085
gene id: 452863:ACHL_RS10085
uniprot id: B8H8U8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS07070
gene id: 452863:ACHL_RS07070
uniprot id: B8HFQ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452863:ACHL RS12560
gene id: 452863:ACHL_RS12560
uniprot id: B8HBR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS14290
gene id: 452863:ACHL_RS14290
uniprot id: B8HDS5
names: Similarity
messages: Belongs to the isochorismate synthase family.

452863:ACHL RS03395
gene id: 452863:ACHL_RS03395
uniprot id: B8HBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

452863:ACHL RS03985
gene id: 452863:ACHL_RS03985
uniprot id: B8HCK8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

452863:ACHL RS06405
gene id: 452863:ACHL_RS06405
uniprot id: B8HF00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

452863:ACHL RS16425
gene id: 452863:ACHL_RS16425
uniprot id: B8HG36
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

452863:ACHL RS09800
gene id: 452863:ACHL_RS09800
uniprot id: B8H8P1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS06000
gene id: 452863:ACHL_RS06000
uniprot id: B8HES0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

452863:ACHL RS22970
gene id: 452863:ACHL_RS22970
uniprot id: B8HJC9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452863:ACHL RS02920
gene id: 452863:ACHL_RS02920
uniprot id: B8HBA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

452863:ACHL RS11360
gene id: 452863:ACHL_RS11360
uniprot id: B8HAC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

452863:ACHL RS03680
gene id: 452863:ACHL_RS03680
uniprot id: B8HC23
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

452863:ACHL RS10140
gene id: 452863:ACHL_RS10140
uniprot id: B8H9B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

452863:ACHL RS17625
gene id: 452863:ACHL_RS17625
uniprot id: B8HHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS17410
gene id: 452863:ACHL_RS17410
uniprot id: B8HHE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

452863:ACHL RS19125
gene id: 452863:ACHL_RS19125
uniprot id: B8H7W3
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS01495
gene id: 452863:ACHL_RS01495
uniprot id: B8H9R8
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04040
gene id: 452863:ACHL_RS04040
uniprot id: B8HCL9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS10665
gene id: 452863:ACHL_RS10665
uniprot id: B8H9L7
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

452863:ACHL RS09695
gene id: 452863:ACHL_RS09695
uniprot id: B8H8M0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

452863:ACHL RS11925
gene id: 452863:ACHL_RS11925
uniprot id: B8HB11
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

452863:ACHL RS11815
gene id: 452863:ACHL_RS11815
uniprot id: B8HAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

452863:ACHL RS23060
gene id: 452863:ACHL_RS23060
uniprot id: B8HJE7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

452863:ACHL RS03665
gene id: 452863:ACHL_RS03665
uniprot id: B8HC20
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

452863:ACHL RS09835
gene id: 452863:ACHL_RS09835
uniprot id: B8H8P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

452863:ACHL RS06225
gene id: 452863:ACHL_RS06225
uniprot id: B8HEW4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

452863:ACHL RS00880
gene id: 452863:ACHL_RS00880
uniprot id: B8H919
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11255
gene id: 452863:ACHL_RS11255
uniprot id: B8HAA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS10435
gene id: 452863:ACHL_RS10435
uniprot id: B8H9H6
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS02660
gene id: 452863:ACHL_RS02660
uniprot id: B8HB50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

452863:ACHL RS09230
gene id: 452863:ACHL_RS09230
uniprot id: B8H7M8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

452863:ACHL RS15030
gene id: 452863:ACHL_RS15030
uniprot id: B8HEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

452863:ACHL RS05675
gene id: 452863:ACHL_RS05675
uniprot id: B8HE87
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS17445
gene id: 452863:ACHL_RS17445
uniprot id: B8HHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

452863:ACHL RS17695
gene id: 452863:ACHL_RS17695
uniprot id: B8H6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS04595
gene id: 452863:ACHL_RS04595
uniprot id: B8HDA0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

452863:ACHL RS21950
gene id: 452863:ACHL_RS21950
uniprot id: B8HIR2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11840
gene id: 452863:ACHL_RS11840
uniprot id: B8HAZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

452863:ACHL RS10530
gene id: 452863:ACHL_RS10530
uniprot id: B8H9J1
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

452863:ACHL RS18615
gene id: 452863:ACHL_RS18615
uniprot id: B8H770
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

452863:ACHL RS18120
gene id: 452863:ACHL_RS18120
uniprot id: B8H6P6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS00435
gene id: 452863:ACHL_RS00435
uniprot id: B8H8B4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS16250
gene id: 452863:ACHL_RS16250
uniprot id: B8HG03
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS14275
gene id: 452863:ACHL_RS14275
uniprot id: B8HDS2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

452863:ACHL RS10975
gene id: 452863:ACHL_RS10975
uniprot id: B8HA51
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

452863:ACHL RS06585
gene id: 452863:ACHL_RS06585
uniprot id: B8HFG1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

452863:ACHL RS03440
gene id: 452863:ACHL_RS03440
uniprot id: B8HBX6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

452863:ACHL RS15420
gene id: 452863:ACHL_RS15420
uniprot id: B8HF62
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13145
gene id: 452863:ACHL_RS13145
uniprot id: B8HCF0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

452863:ACHL RS18320
gene id: 452863:ACHL_RS18320
uniprot id: B8H710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS03460
gene id: 452863:ACHL_RS03460
uniprot id: B8HBY0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

452863:ACHL RS22475
gene id: 452863:ACHL_RS22475
uniprot id: B8HJ25
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

452863:ACHL RS12465
gene id: 452863:ACHL_RS12465
uniprot id: B8HBP5
names: Similarity
messages: Belongs to the PspA/IM30 family.

452863:ACHL RS01515
gene id: 452863:ACHL_RS01515
uniprot id: B8H9S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

452863:ACHL RS05430
gene id: 452863:ACHL_RS05430
uniprot id: B8HE38
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

452863:ACHL RS20315
gene id: 452863:ACHL_RS20315
uniprot id: B8HHS7
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS11845
gene id: 452863:ACHL_RS11845
uniprot id: B8HAZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

452863:ACHL RS04945
gene id: 452863:ACHL_RS04945
uniprot id: B8HDH1
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

452863:ACHL RS01600
gene id: 452863:ACHL_RS01600
uniprot id: B8H9T9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

452863:ACHL RS07325
gene id: 452863:ACHL_RS07325
uniprot id: B8HG82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

452863:ACHL RS13710
gene id: 452863:ACHL_RS13710
uniprot id: B8HD33
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08755
gene id: 452863:ACHL_RS08755
uniprot id: B8H6Z4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS07975
gene id: 452863:ACHL_RS07975
uniprot id: B8HGY0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

452863:ACHL RS05630
gene id: 452863:ACHL_RS05630
uniprot id: B8HE78
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

452863:ACHL RS02810
gene id: 452863:ACHL_RS02810
uniprot id: B8HB80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

452863:ACHL RS16285
gene id: 452863:ACHL_RS16285
uniprot id: B8HG10
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

452863:ACHL RS14460
gene id: 452863:ACHL_RS14460
uniprot id: B8HDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

452863:ACHL RS05970
gene id: 452863:ACHL_RS05970
uniprot id: B8HER4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS08800
gene id: 452863:ACHL_RS08800
uniprot id: B8H703
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452863:ACHL RS06115
gene id: 452863:ACHL_RS06115
uniprot id: B8HEU3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

452863:ACHL RS07925
gene id: 452863:ACHL_RS07925
uniprot id: B8HGX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS22935
gene id: 452863:ACHL_RS22935
uniprot id: B8HJC2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

452863:ACHL RS13925
gene id: 452863:ACHL_RS13925
uniprot id: B8HD76
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452863:ACHL RS10655
gene id: 452863:ACHL_RS10655
uniprot id: B8H9L5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

452863:ACHL RS15685
gene id: 452863:ACHL_RS15685
uniprot id: B8HFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS07930
gene id: 452863:ACHL_RS07930
uniprot id: B8HGX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

452863:ACHL RS10035
gene id: 452863:ACHL_RS10035
uniprot id: B8H8T8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS11600
gene id: 452863:ACHL_RS11600
uniprot id: B8HAU6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

452863:ACHL RS10800
gene id: 452863:ACHL_RS10800
uniprot id: B8H9P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

452863:ACHL RS01555
gene id: 452863:ACHL_RS01555
uniprot id: B8H9T0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

452863:ACHL RS12580
gene id: 452863:ACHL_RS12580
uniprot id: B8HBR6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

452863:ACHL RS12610
gene id: 452863:ACHL_RS12610
uniprot id: B8HBS2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

452863:ACHL RS06750
gene id: 452863:ACHL_RS06750
uniprot id: B8HFJ3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

452863:ACHL RS23305
gene id: 452863:ACHL_RS23305
uniprot id: B8HJJ5
names: Similarity
messages: Belongs to the ParB family.

452863:ACHL RS16990
gene id: 452863:ACHL_RS16990
uniprot id: B8HGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS13295
gene id: 452863:ACHL_RS13295
uniprot id: B8HCI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

452863:ACHL RS19050
gene id: 452863:ACHL_RS19050
uniprot id: B8H7U8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

452863:ACHL RS08095
gene id: 452863:ACHL_RS08095
uniprot id: B8HH05
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

452863:ACHL RS09680
gene id: 452863:ACHL_RS09680
uniprot id: B8H8L7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

452863:ACHL RS19335
gene id: 452863:ACHL_RS19335
uniprot id: B8H805
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

452863:ACHL RS18410
gene id: 452863:ACHL_RS18410
uniprot id: B8H728
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS09935
gene id: 452863:ACHL_RS09935
uniprot id: B8H8R8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

452863:ACHL RS07765
gene id: 452863:ACHL_RS07765
uniprot id: B8HGG6
names: Similarity
messages: Belongs to the FPG family.

452863:ACHL RS09810
gene id: 452863:ACHL_RS09810
uniprot id: B8H8P3
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

452863:ACHL RS09445
gene id: 452863:ACHL_RS09445
uniprot id: B8H7R9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

452863:ACHL RS08615
gene id: 452863:ACHL_RS08615
uniprot id: B8H6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

452863:ACHL RS02970
gene id: 452863:ACHL_RS02970
uniprot id: B8HBB2
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS00830
gene id: 452863:ACHL_RS00830
uniprot id: B8H910
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

452863:ACHL RS11365
gene id: 452863:ACHL_RS11365
uniprot id: B8HAC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

452863:ACHL RS02675
gene id: 452863:ACHL_RS02675
uniprot id: B8HB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

452863:ACHL RS18930
gene id: 452863:ACHL_RS18930
uniprot id: B8H7C7
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04515
gene id: 452863:ACHL_RS04515
uniprot id: B8HCV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

452863:ACHL RS18515
gene id: 452863:ACHL_RS18515
uniprot id: B8H749
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

452863:ACHL RS07915
gene id: 452863:ACHL_RS07915
uniprot id: B8HGW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

452863:ACHL RS14655
gene id: 452863:ACHL_RS14655
uniprot id: B8HEC2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

452863:ACHL RS07680
gene id: 452863:ACHL_RS07680
uniprot id: B8HGF0
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

452863:ACHL RS05315
gene id: 452863:ACHL_RS05315
uniprot id: B8HE15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

452863:ACHL RS11635
gene id: 452863:ACHL_RS11635
uniprot id: B8HAV3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06610
gene id: 452863:ACHL_RS06610
uniprot id: B8HFG6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS18935
gene id: 452863:ACHL_RS18935
uniprot id: B8H7S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

452863:ACHL RS10625
gene id: 452863:ACHL_RS10625
uniprot id: B8H9K9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS17515
gene id: 452863:ACHL_RS17515
uniprot id: B8HHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

452863:ACHL RS11785
gene id: 452863:ACHL_RS11785
uniprot id: B8HAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

452863:ACHL RS08510
gene id: 452863:ACHL_RS08510
uniprot id: B8H6U8
names: Similarity
messages: Belongs to the TrpC family.

452863:ACHL RS15015
gene id: 452863:ACHL_RS15015
uniprot id: B8HEK4
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS19745
gene id: 452863:ACHL_RS19745
uniprot id: B8HHJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS13450
gene id: 452863:ACHL_RS13450
uniprot id: B8HCY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS05925
gene id: 452863:ACHL_RS05925
uniprot id: B8HEQ5
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS07000
gene id: 452863:ACHL_RS07000
uniprot id: B8HFP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

452863:ACHL RS16125
gene id: 452863:ACHL_RS16125
uniprot id: B8HFX9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

452863:ACHL RS15035
gene id: 452863:ACHL_RS15035
uniprot id: B8HEK8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

452863:ACHL RS05135
gene id: 452863:ACHL_RS05135
uniprot id: B8HDK8
names: Similarity
messages: Belongs to the AHA1 family.

452863:ACHL RS04295
gene id: 452863:ACHL_RS04295
uniprot id: B8HCR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

452863:ACHL RS04600
gene id: 452863:ACHL_RS04600
uniprot id: B8HDA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS11275
gene id: 452863:ACHL_RS11275
uniprot id: B8HAA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

452863:ACHL RS16805
gene id: 452863:ACHL_RS16805
uniprot id: B8HGP1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

452863:ACHL RS09220
gene id: 452863:ACHL_RS09220
uniprot id: B8H7M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

452863:ACHL RS10095
gene id: 452863:ACHL_RS10095
uniprot id: B8H8V0
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

452863:ACHL RS18675
gene id: 452863:ACHL_RS18675
uniprot id: B8H776
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

452863:ACHL RS13230
gene id: 452863:ACHL_RS13230
uniprot id: B8HCG7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

452863:ACHL RS07425
gene id: 452863:ACHL_RS07425
uniprot id: B8HGA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

452863:ACHL RS09660
gene id: 452863:ACHL_RS09660
uniprot id: B8H8L3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

452863:ACHL RS20165
gene id: 452863:ACHL_RS20165
uniprot id: B8HHP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452863:ACHL RS14625
gene id: 452863:ACHL_RS14625
uniprot id: B8HEB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

452863:ACHL RS15410
gene id: 452863:ACHL_RS15410
uniprot id: B8HF60
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

452863:ACHL RS09865
gene id: 452863:ACHL_RS09865
uniprot id: B8H8Q4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

452863:ACHL RS06270
gene id: 452863:ACHL_RS06270
uniprot id: B8HEX3
names: Similarity
messages: Belongs to the peptidase A24 family.

452863:ACHL RS11075
gene id: 452863:ACHL_RS11075
uniprot id: B8HA70
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

452863:ACHL RS07740
gene id: 452863:ACHL_RS07740
uniprot id: B8HGG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

452863:ACHL RS11940
gene id: 452863:ACHL_RS11940
uniprot id: B8HB13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

452863:ACHL RS08415
gene id: 452863:ACHL_RS08415
uniprot id: B8HH62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

452863:ACHL RS07645
gene id: 452863:ACHL_RS07645
uniprot id: B8HGE3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

452863:ACHL RS02960
gene id: 452863:ACHL_RS02960
uniprot id: B8HBB0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

452863:ACHL RS16595
gene id: 452863:ACHL_RS16595
uniprot id: B8HGJ8
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06525
gene id: 452863:ACHL_RS06525
uniprot id: B8HFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

452863:ACHL RS18920
gene id: 452863:ACHL_RS18920
uniprot id: B8H7C5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

452863:ACHL RS19830
gene id: 452863:ACHL_RS19830
uniprot id: B8HHK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452863:ACHL RS17380
gene id: 452863:ACHL_RS17380
uniprot id: B8HHD4
names: Similarity
messages: Belongs to the GcvT family.

452863:ACHL RS20310
gene id: 452863:ACHL_RS20310
uniprot id: B8HHS6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

452863:ACHL RS16930
gene id: 452863:ACHL_RS16930
uniprot id: B8HGR8
names: Similarity
messages: Belongs to the DapA family.

452863:ACHL RS07955
gene id: 452863:ACHL_RS07955
uniprot id: B8HGX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

452863:ACHL RS12060
gene id: 452863:ACHL_RS12060
uniprot id: B8HB38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

452863:ACHL RS18405
gene id: 452863:ACHL_RS18405
uniprot id: B8H727
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06145
gene id: 452863:ACHL_RS06145
uniprot id: B8HEU9
names: Similarity
messages: Belongs to the peptidase S8 family.

452863:ACHL RS12235
gene id: 452863:ACHL_RS12235
uniprot id: B8HBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS17510
gene id: 452863:ACHL_RS17510
uniprot id: B8HHG0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS05310
gene id: 452863:ACHL_RS05310
uniprot id: B8HE14
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS00455
gene id: 452863:ACHL_RS00455
uniprot id: B8H8B8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

452863:ACHL RS07995
gene id: 452863:ACHL_RS07995
uniprot id: B8HGY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

452863:ACHL RS08495
gene id: 452863:ACHL_RS08495
uniprot id: B8H6U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

452863:ACHL RS16760
gene id: 452863:ACHL_RS16760
uniprot id: B8HGN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS09880
gene id: 452863:ACHL_RS09880
uniprot id: B8H8Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

452863:ACHL RS05625
gene id: 452863:ACHL_RS05625
uniprot id: B8HE77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS07105
gene id: 452863:ACHL_RS07105
uniprot id: B8HFR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

452863:ACHL RS11890
gene id: 452863:ACHL_RS11890
uniprot id: B8HB04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS01735
gene id: 452863:ACHL_RS01735
uniprot id: B8H9W7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS01940
gene id: 452863:ACHL_RS01940
uniprot id: B8HA08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

452863:ACHL RS08070
gene id: 452863:ACHL_RS08070
uniprot id: B8HH00
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

452863:ACHL RS13440
gene id: 452863:ACHL_RS13440
uniprot id: B8HCX9
names: Similarity
messages: Belongs to the peptidase S58 family.

452863:ACHL RS17475
gene id: 452863:ACHL_RS17475
uniprot id: B8HHF3
names: Similarity
messages: Belongs to the TrpF family.

452863:ACHL RS12905
gene id: 452863:ACHL_RS12905
uniprot id: B8HCA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS11835
gene id: 452863:ACHL_RS11835
uniprot id: B8HAZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

452863:ACHL RS02455
gene id: 452863:ACHL_RS02455
uniprot id: B8HAN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

452863:ACHL RS07530
gene id: 452863:ACHL_RS07530
uniprot id: B8HGC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

452863:ACHL RS00960
gene id: 452863:ACHL_RS00960
uniprot id: B8H935
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

452863:ACHL RS07910
gene id: 452863:ACHL_RS07910
uniprot id: B8HGW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

452863:ACHL RS19515
gene id: 452863:ACHL_RS19515
uniprot id: B8H841
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

452863:ACHL RS20980
gene id: 452863:ACHL_RS20980
uniprot id: B8HI65
names: Similarity
messages: Belongs to the GSP E family.

452863:ACHL RS15480
gene id: 452863:ACHL_RS15480
uniprot id: B8HF74
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11250
gene id: 452863:ACHL_RS11250
uniprot id: B8HAA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

452863:ACHL RS14055
gene id: 452863:ACHL_RS14055
uniprot id: B8HDM9
names: Similarity
messages: Belongs to the catalase family.

452863:ACHL RS10860
gene id: 452863:ACHL_RS10860
uniprot id: B8HA31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

452863:ACHL RS08655
gene id: 452863:ACHL_RS08655
uniprot id: B8H6X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS05410
gene id: 452863:ACHL_RS05410
uniprot id: B8HE34
names: Similarity
messages: Belongs to the TPP enzyme family.

452863:ACHL RS11995
gene id: 452863:ACHL_RS11995
uniprot id: B8HB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS00190
gene id: 452863:ACHL_RS00190
uniprot id: B8H864
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

452863:ACHL RS05050
gene id: 452863:ACHL_RS05050
uniprot id: B8HDJ1
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS16005
gene id: 452863:ACHL_RS16005
uniprot id: B8HFV5
names: Similarity
messages: Belongs to the GARS family.

452863:ACHL RS03690
gene id: 452863:ACHL_RS03690
uniprot id: B8HC25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452863:ACHL RS18505
gene id: 452863:ACHL_RS18505
uniprot id: B8H747
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS18195
gene id: 452863:ACHL_RS18195
uniprot id: B8H6R1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

452863:ACHL RS13260
gene id: 452863:ACHL_RS13260
uniprot id: B8HCH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

452863:ACHL RS06580
gene id: 452863:ACHL_RS06580
uniprot id: B8HFG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

452863:ACHL RS14175
gene id: 452863:ACHL_RS14175
uniprot id: B8HDQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

452863:ACHL RS00930
gene id: 452863:ACHL_RS00930
uniprot id: B8H930
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

452863:ACHL RS16620
gene id: 452863:ACHL_RS16620
uniprot id: B8HGK3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

452863:ACHL RS04770
gene id: 452863:ACHL_RS04770
uniprot id: B8HDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

452863:ACHL RS09265
gene id: 452863:ACHL_RS09265
uniprot id: B8H7N5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

452863:ACHL RS12165
gene id: 452863:ACHL_RS12165
uniprot id: B8HBI5
names: Similarity
messages: Belongs to the GSP E family.

452863:ACHL RS06940
gene id: 452863:ACHL_RS06940
uniprot id: B8HFN1
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11900
gene id: 452863:ACHL_RS11900
uniprot id: B8HB06
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

452863:ACHL RS12470
gene id: 452863:ACHL_RS12470
uniprot id: B8HBP6
names: Similarity
messages: Belongs to the DNA photolyase family.

452863:ACHL RS14155
gene id: 452863:ACHL_RS14155
uniprot id: B8HDP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

452863:ACHL RS16275
gene id: 452863:ACHL_RS16275
uniprot id: B8HG08
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08145
gene id: 452863:ACHL_RS08145
uniprot id: B8HH15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

452863:ACHL RS13210
gene id: 452863:ACHL_RS13210
uniprot id: B8HCG3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

452863:ACHL RS18050
gene id: 452863:ACHL_RS18050
uniprot id: B8H6N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS11295
gene id: 452863:ACHL_RS11295
uniprot id: B8HAB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

452863:ACHL RS00935
gene id: 452863:ACHL_RS00935
uniprot id: B8H931
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08660
gene id: 452863:ACHL_RS08660
uniprot id: B8H6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS17970
gene id: 452863:ACHL_RS17970
uniprot id: B8H6L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

452863:ACHL RS08970
gene id: 452863:ACHL_RS08970
uniprot id: B8H7H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS07235
gene id: 452863:ACHL_RS07235
uniprot id: B8HG65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

452863:ACHL RS06280
gene id: 452863:ACHL_RS06280
uniprot id: B8HEX5
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01615
gene id: 452863:ACHL_RS01615
uniprot id: B8H9U2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13725
gene id: 452863:ACHL_RS13725
uniprot id: B8HD36
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS10130
gene id: 452863:ACHL_RS10130
uniprot id: B8H8V7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

452863:ACHL RS11710
gene id: 452863:ACHL_RS11710
uniprot id: B8HAW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

452863:ACHL RS09135
gene id: 452863:ACHL_RS09135
uniprot id: B8H7K9
names: Similarity
messages: Belongs to the peptidase S33 family.

452863:ACHL RS16110
gene id: 452863:ACHL_RS16110
uniprot id: B8HFX6
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

452863:ACHL RS07505
gene id: 452863:ACHL_RS07505
uniprot id: B8HGB8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

452863:ACHL RS19165
gene id: 452863:ACHL_RS19165
uniprot id: B8H7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

452863:ACHL RS12125
gene id: 452863:ACHL_RS12125
uniprot id: B8HBH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

452863:ACHL RS07410
gene id: 452863:ACHL_RS07410
uniprot id: B8HG99
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

452863:ACHL RS13150
gene id: 452863:ACHL_RS13150
uniprot id: B8HCF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

452863:ACHL RS13380
gene id: 452863:ACHL_RS13380
uniprot id: B8HCW7
names: Similarity
messages: Belongs to the GSP E family.

452863:ACHL RS18945
gene id: 452863:ACHL_RS18945
uniprot id: B8H7S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

452863:ACHL RS17155
gene id: 452863:ACHL_RS17155
uniprot id: B8HH89
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12410
gene id: 452863:ACHL_RS12410
uniprot id: B8HBN4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

452863:ACHL RS19510
gene id: 452863:ACHL_RS19510
uniprot id: B8H840
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS01785
gene id: 452863:ACHL_RS01785
uniprot id: B8H9X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

452863:ACHL RS08255
gene id: 452863:ACHL_RS08255
uniprot id: B8HH36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

452863:ACHL RS03085
gene id: 452863:ACHL_RS03085
uniprot id: B8HBD0
names: Similarity
messages: Belongs to the asp23 family.

452863:ACHL RS17685
gene id: 452863:ACHL_RS17685
uniprot id: B8H6G0
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

452863:ACHL RS13545
gene id: 452863:ACHL_RS13545
uniprot id: B8HD00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

452863:ACHL RS22925
gene id: 452863:ACHL_RS22925
uniprot id: B8HJB9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

452863:ACHL RS11620
gene id: 452863:ACHL_RS11620
uniprot id: B8HAV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

452863:ACHL RS01925
gene id: 452863:ACHL_RS01925
uniprot id: B8HA05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

452863:ACHL RS12085
gene id: 452863:ACHL_RS12085
uniprot id: B8HB43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

452863:ACHL RS06485
gene id: 452863:ACHL_RS06485
uniprot id: B8HFE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

452863:ACHL RS09150
gene id: 452863:ACHL_RS09150
uniprot id: B8H7L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

452863:ACHL RS07100
gene id: 452863:ACHL_RS07100
uniprot id: B8HFR2
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

452863:ACHL RS07320
gene id: 452863:ACHL_RS07320
uniprot id: B8HG81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

452863:ACHL RS03915
gene id: 452863:ACHL_RS03915
uniprot id: B8HC67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS22680
gene id: 452863:ACHL_RS22680
uniprot id: B8HJ67
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

452863:ACHL RS00090
gene id: 452863:ACHL_RS00090
uniprot id: B8H7E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

452863:ACHL RS09510
gene id: 452863:ACHL_RS09510
uniprot id: B8H8I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

452863:ACHL RS17395
gene id: 452863:ACHL_RS17395
uniprot id: B8HHD7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS20140
gene id: 452863:ACHL_RS20140
uniprot id: B8HHP2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

452863:ACHL RS13070
gene id: 452863:ACHL_RS13070
uniprot id: B8HCD6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

452863:ACHL RS13595
gene id: 452863:ACHL_RS13595
uniprot id: B8HD11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

452863:ACHL RS08245
gene id: 452863:ACHL_RS08245
uniprot id: B8HH35
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

452863:ACHL RS17825
gene id: 452863:ACHL_RS17825
uniprot id: B8H6I8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

452863:ACHL RS07125
gene id: 452863:ACHL_RS07125
uniprot id: B8HG44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

452863:ACHL RS12725
gene id: 452863:ACHL_RS12725
uniprot id: B8HBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

452863:ACHL RS03190
gene id: 452863:ACHL_RS03190
uniprot id: B8HBF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452863:ACHL RS00600
gene id: 452863:ACHL_RS00600
uniprot id: B8H8E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

452863:ACHL RS06325
gene id: 452863:ACHL_RS06325
uniprot id: B8HEY4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

452863:ACHL RS03545
gene id: 452863:ACHL_RS03545
uniprot id: B8HBZ6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS11430
gene id: 452863:ACHL_RS11430
uniprot id: B8HAD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452863:ACHL RS18420
gene id: 452863:ACHL_RS18420
uniprot id: B8H730
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS15515
gene id: 452863:ACHL_RS15515
uniprot id: B8HF81
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08075
gene id: 452863:ACHL_RS08075
uniprot id: B8HH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm

452863:ACHL RS00480
gene id: 452863:ACHL_RS00480
uniprot id: B8H8C3
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

452863:ACHL RS04460
gene id: 452863:ACHL_RS04460
uniprot id: B8HB48
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

452863:ACHL RS03490
gene id: 452863:ACHL_RS03490
uniprot id: B8HBY5
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

452863:ACHL RS09100
gene id: 452863:ACHL_RS09100
uniprot id: B8H7K2
names: Similarity
messages: Belongs to the IMPACT family.

452863:ACHL RS02460
gene id: 452863:ACHL_RS02460
uniprot id: B8HAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

452863:ACHL RS18470
gene id: 452863:ACHL_RS18470
uniprot id: B8H740
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

452863:ACHL RS08885
gene id: 452863:ACHL_RS08885
uniprot id: B8H7G0
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

452863:ACHL RS12185
gene id: 452863:ACHL_RS12185
uniprot id: B8HBI9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

452863:ACHL RS00415
gene id: 452863:ACHL_RS00415
uniprot id: B8H8B0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS06715
gene id: 452863:ACHL_RS06715
uniprot id: B8HFI6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS00400
gene id: 452863:ACHL_RS00400
uniprot id: B8H8A7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS03385
gene id: 452863:ACHL_RS03385
uniprot id: B8HBW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

452863:ACHL RS08440
gene id: 452863:ACHL_RS08440
uniprot id: B8H6T5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

452863:ACHL RS06955
gene id: 452863:ACHL_RS06955
uniprot id: B8HFN3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452863:ACHL RS07180
gene id: 452863:ACHL_RS07180
uniprot id: B8HG54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

452863:ACHL RS14260
gene id: 452863:ACHL_RS14260
uniprot id: B8HDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

452863:ACHL RS10770
gene id: 452863:ACHL_RS10770
uniprot id: B8H9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

452863:ACHL RS15875
gene id: 452863:ACHL_RS15875
uniprot id: B8HFS9
names: Similarity
messages: Belongs to the GSP E family.

452863:ACHL RS14945
gene id: 452863:ACHL_RS14945
uniprot id: B8HEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

452863:ACHL RS15925
gene id: 452863:ACHL_RS15925
uniprot id: B8HFT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS17990
gene id: 452863:ACHL_RS17990
uniprot id: B8H6M0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

452863:ACHL RS04465
gene id: 452863:ACHL_RS04465
uniprot id: B8HCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

452863:ACHL RS04860
gene id: 452863:ACHL_RS04860
uniprot id: B8HDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

452863:ACHL RS04340
gene id: 452863:ACHL_RS04340
uniprot id: B8HCS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

452863:ACHL RS07600
gene id: 452863:ACHL_RS07600
uniprot id: B8HGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS03855
gene id: 452863:ACHL_RS03855
uniprot id: B8HC55
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

452863:ACHL RS22830
gene id: 452863:ACHL_RS22830
uniprot id: B8HJA0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

452863:ACHL RS19190
gene id: 452863:ACHL_RS19190
uniprot id: B8H7X6
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

452863:ACHL RS11655
gene id: 452863:ACHL_RS11655
uniprot id: B8HAV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

452863:ACHL RS10120
gene id: 452863:ACHL_RS10120
uniprot id: B8H8V5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

452863:ACHL RS07400
gene id: 452863:ACHL_RS07400
uniprot id: B8HG97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

452863:ACHL RS04405
gene id: 452863:ACHL_RS04405
uniprot id: B8HCT4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

452863:ACHL RS19095
gene id: 452863:ACHL_RS19095
uniprot id: B8H7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS00620
gene id: 452863:ACHL_RS00620
uniprot id: B8H8F1
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

452863:ACHL RS13235
gene id: 452863:ACHL_RS13235
uniprot id: B8HCG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS03205
gene id: 452863:ACHL_RS03205
uniprot id: B8HBF4
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS03495
gene id: 452863:ACHL_RS03495
uniprot id: B8HBY6
names: Similarity
messages: Belongs to the stealth family.

452863:ACHL RS06770
gene id: 452863:ACHL_RS06770
uniprot id: B8HFJ7
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS07970
gene id: 452863:ACHL_RS07970
uniprot id: B8HGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

452863:ACHL RS23165
gene id: 452863:ACHL_RS23165
uniprot id: B8HJG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS00180
gene id: 452863:ACHL_RS00180
uniprot id: B8H862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS07300
gene id: 452863:ACHL_RS07300
uniprot id: B8HG77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

452863:ACHL RS18875
gene id: 452863:ACHL_RS18875
uniprot id: B8H7B6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

452863:ACHL RS04330
gene id: 452863:ACHL_RS04330
uniprot id: B8HCS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

452863:ACHL RS04335
gene id: 452863:ACHL_RS04335
uniprot id: B8HCS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

452863:ACHL RS03800
gene id: 452863:ACHL_RS03800
uniprot id: B8HC46
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452863:ACHL RS07900
gene id: 452863:ACHL_RS07900
uniprot id: B8HGW5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS01975
gene id: 452863:ACHL_RS01975
uniprot id: B8HA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS19460
gene id: 452863:ACHL_RS19460
uniprot id: B8H830
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01790
gene id: 452863:ACHL_RS01790
uniprot id: B8H9X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

452863:ACHL RS00075
gene id: 452863:ACHL_RS00075
uniprot id: B8H7E0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

452863:ACHL RS12955
gene id: 452863:ACHL_RS12955
uniprot id: B8HCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

452863:ACHL RS07750
gene id: 452863:ACHL_RS07750
uniprot id: B8HGG4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

452863:ACHL RS03235
gene id: 452863:ACHL_RS03235
uniprot id: B8HBG0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

452863:ACHL RS01930
gene id: 452863:ACHL_RS01930
uniprot id: B8HA06
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

452863:ACHL RS20555
gene id: 452863:ACHL_RS20555
uniprot id: B8HHX6
names: Similarity
messages: Belongs to the PspA/IM30 family.

452863:ACHL RS05275
gene id: 452863:ACHL_RS05275
uniprot id: B8HE07
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

452863:ACHL RS05910
gene id: 452863:ACHL_RS05910
uniprot id: B8HEQ2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS10790
gene id: 452863:ACHL_RS10790
uniprot id: B8H9P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

452863:ACHL RS00125
gene id: 452863:ACHL_RS00125
uniprot id: B8H852
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS09270
gene id: 452863:ACHL_RS09270
uniprot id: B8H7N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

452863:ACHL RS10395
gene id: 452863:ACHL_RS10395
uniprot id: B8H9G9
names: Similarity
messages: Belongs to the peptidase C40 family.

452863:ACHL RS10880
gene id: 452863:ACHL_RS10880
uniprot id: B8HA35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

452863:ACHL RS18095
gene id: 452863:ACHL_RS18095
uniprot id: B8H6P1
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

452863:ACHL RS04300
gene id: 452863:ACHL_RS04300
uniprot id: B8HCR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

452863:ACHL RS12585
gene id: 452863:ACHL_RS12585
uniprot id: B8HBR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS06810
gene id: 452863:ACHL_RS06810
uniprot id: B8HFK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

452863:ACHL RS14000
gene id: 452863:ACHL_RS14000
uniprot id: B8HD91
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS00325
gene id: 452863:ACHL_RS00325
uniprot id: B8H892
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01630
gene id: 452863:ACHL_RS01630
uniprot id: B8H9U5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS01470
gene id: 452863:ACHL_RS01470
uniprot id: B8H9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS09455
gene id: 452863:ACHL_RS09455
uniprot id: B8H7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS03165
gene id: 452863:ACHL_RS03165
uniprot id: B8HBE6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

452863:ACHL RS09650
gene id: 452863:ACHL_RS09650
uniprot id: B8H8L1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

452863:ACHL RS01935
gene id: 452863:ACHL_RS01935
uniprot id: B8HA07
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

452863:ACHL RS19695
gene id: 452863:ACHL_RS19695
uniprot id: B8H8Y5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

452863:ACHL RS08100
gene id: 452863:ACHL_RS08100
uniprot id: B8HH06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

452863:ACHL RS12090
gene id: 452863:ACHL_RS12090
uniprot id: B8HB44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

452863:ACHL RS16115
gene id: 452863:ACHL_RS16115
uniprot id: B8HFX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

452863:ACHL RS13425
gene id: 452863:ACHL_RS13425
uniprot id: B8HCX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

452863:ACHL RS01730
gene id: 452863:ACHL_RS01730
uniprot id: B8H9W6
names: Similarity
messages: Belongs to the DapA family.

452863:ACHL RS23500
gene id: 452863:ACHL_RS23500
uniprot id: B8HHM9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04320
gene id: 452863:ACHL_RS04320
uniprot id: B8HCS1
names: Similarity
messages: Belongs to the barstar family.

452863:ACHL RS13645
gene id: 452863:ACHL_RS13645
uniprot id: B8HD21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

452863:ACHL RS17725
gene id: 452863:ACHL_RS17725
uniprot id: B8H6G8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS09740
gene id: 452863:ACHL_RS09740
uniprot id: B8H8M9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

452863:ACHL RS03030
gene id: 452863:ACHL_RS03030
uniprot id: B8HBC3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS10950
gene id: 452863:ACHL_RS10950
uniprot id: B8HA47
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

452863:ACHL RS04760
gene id: 452863:ACHL_RS04760
uniprot id: B8HDD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

452863:ACHL RS09480
gene id: 452863:ACHL_RS09480
uniprot id: B8H7S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

452863:ACHL RS00080
gene id: 452863:ACHL_RS00080
uniprot id: B8H7E1
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS15060
gene id: 452863:ACHL_RS15060
uniprot id: B8HEL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

452863:ACHL RS18465
gene id: 452863:ACHL_RS18465
uniprot id: B8H739
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS14695
gene id: 452863:ACHL_RS14695
uniprot id: B8HED0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

452863:ACHL RS11150
gene id: 452863:ACHL_RS11150
uniprot id: B8HA84
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

452863:ACHL RS07560
gene id: 452863:ACHL_RS07560
uniprot id: B8HGC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

452863:ACHL RS14755
gene id: 452863:ACHL_RS14755
uniprot id: B8HEE2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS15405
gene id: 452863:ACHL_RS15405
uniprot id: B8HF59
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

452863:ACHL RS10240
gene id: 452863:ACHL_RS10240
uniprot id: B8H9D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

452863:ACHL RS08920
gene id: 452863:ACHL_RS08920
uniprot id: B8H7G7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS11145
gene id: 452863:ACHL_RS11145
uniprot id: B8HA83
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

452863:ACHL RS13035
gene id: 452863:ACHL_RS13035
uniprot id: B8HCC9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

452863:ACHL RS02650
gene id: 452863:ACHL_RS02650
uniprot id: B8HB48
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

452863:ACHL RS01640
gene id: 452863:ACHL_RS01640
uniprot id: B8H9U8
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

452863:ACHL RS11455
gene id: 452863:ACHL_RS11455
uniprot id: B8HAE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS03260
gene id: 452863:ACHL_RS03260
uniprot id: B8HBG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS04215
gene id: 452863:ACHL_RS04215
uniprot id: B8HCQ1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

452863:ACHL RS06805
gene id: 452863:ACHL_RS06805
uniprot id: B8HFK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

452863:ACHL RS06540
gene id: 452863:ACHL_RS06540
uniprot id: B8HFF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

452863:ACHL RS19350
gene id: 452863:ACHL_RS19350
uniprot id: B8H808
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS19475
gene id: 452863:ACHL_RS19475
uniprot id: B8H833
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

452863:ACHL RS01465
gene id: 452863:ACHL_RS01465
uniprot id: B8H9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS19505
gene id: 452863:ACHL_RS19505
uniprot id: B8H839
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

452863:ACHL RS16335
gene id: 452863:ACHL_RS16335
uniprot id: B8HG19
names: Similarity
messages: Belongs to the AHA1 family.

452863:ACHL RS22790
gene id: 452863:ACHL_RS22790
uniprot id: B8HJ90
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

452863:ACHL RS11735
gene id: 452863:ACHL_RS11735
uniprot id: B8HAX3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

452863:ACHL RS17875
gene id: 452863:ACHL_RS17875
uniprot id: B8H6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS07550
gene id: 452863:ACHL_RS07550
uniprot id: B8HGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

452863:ACHL RS06630
gene id: 452863:ACHL_RS06630
uniprot id: B8HFG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

452863:ACHL RS13555
gene id: 452863:ACHL_RS13555
uniprot id: B8HD02
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

452863:ACHL RS16460
gene id: 452863:ACHL_RS16460
uniprot id: B8HGH0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS06290
gene id: 452863:ACHL_RS06290
uniprot id: B8HEX7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

452863:ACHL RS11715
gene id: 452863:ACHL_RS11715
uniprot id: B8HAW9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

452863:ACHL RS04005
gene id: 452863:ACHL_RS04005
uniprot id: B8HCL2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

452863:ACHL RS05720
gene id: 452863:ACHL_RS05720
uniprot id: B8HE95
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452863:ACHL RS13040
gene id: 452863:ACHL_RS13040
uniprot id: B8HCD0
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

452863:ACHL RS04615
gene id: 452863:ACHL_RS04615
uniprot id: B8HDA4
names: Similarity
messages: Belongs to the peptidase C40 family.

452863:ACHL RS03600
gene id: 452863:ACHL_RS03600
uniprot id: B8HC07
names: Similarity
messages: Belongs to the TPP enzyme family.

452863:ACHL RS00495
gene id: 452863:ACHL_RS00495
uniprot id: B8H8C6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

452863:ACHL RS15470
gene id: 452863:ACHL_RS15470
uniprot id: B8HF72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

452863:ACHL RS13385
gene id: 452863:ACHL_RS13385
uniprot id: B8HCW8
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01265
gene id: 452863:ACHL_RS01265
uniprot id: B8H996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS11220
gene id: 452863:ACHL_RS11220
uniprot id: B8HA97
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

452863:ACHL RS07675
gene id: 452863:ACHL_RS07675
uniprot id: B8HGE9
names: Similarity
messages: Belongs to the citrate synthase family.

452863:ACHL RS10900
gene id: 452863:ACHL_RS10900
uniprot id: B8HA37
names: Similarity
messages: Belongs to the FPG family.

452863:ACHL RS06235
gene id: 452863:ACHL_RS06235
uniprot id: B8HEW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

452863:ACHL RS11910
gene id: 452863:ACHL_RS11910
uniprot id: B8HB08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

452863:ACHL RS16835
gene id: 452863:ACHL_RS16835
uniprot id: B8HGP9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS16635
gene id: 452863:ACHL_RS16635
uniprot id: B8HGK6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS15800
gene id: 452863:ACHL_RS15800
uniprot id: B8HFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

452863:ACHL RS02945
gene id: 452863:ACHL_RS02945
uniprot id: B8HBA7
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS11830
gene id: 452863:ACHL_RS11830
uniprot id: B8HAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

452863:ACHL RS02410
gene id: 452863:ACHL_RS02410
uniprot id: B8HAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

452863:ACHL RS11605
gene id: 452863:ACHL_RS11605
uniprot id: B8HAU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

452863:ACHL RS08780
gene id: 452863:ACHL_RS08780
uniprot id: B8H6Z9
names: Similarity
messages: Belongs to the RuBisCO large chain family.

452863:ACHL RS13615
gene id: 452863:ACHL_RS13615
uniprot id: B8HD15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

452863:ACHL RS10780
gene id: 452863:ACHL_RS10780
uniprot id: B8H9N8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

452863:ACHL RS09905
gene id: 452863:ACHL_RS09905
uniprot id: B8H8R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

452863:ACHL RS03750
gene id: 452863:ACHL_RS03750
uniprot id: B8HC37
names: Similarity
messages: Belongs to the FPG family.

452863:ACHL RS05190
gene id: 452863:ACHL_RS05190
uniprot id: B8HDL9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08825
gene id: 452863:ACHL_RS08825
uniprot id: B8H7E9
names: Similarity
messages: Belongs to the glycosyl hydrolase.

452863:ACHL RS13105
gene id: 452863:ACHL_RS13105
uniprot id: B8HCE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

452863:ACHL RS07335
gene id: 452863:ACHL_RS07335
uniprot id: B8HG84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

452863:ACHL RS14070
gene id: 452863:ACHL_RS14070
uniprot id: B8HDN2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13340
gene id: 452863:ACHL_RS13340
uniprot id: B8HCI9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS02975
gene id: 452863:ACHL_RS02975
uniprot id: B8HBB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

452863:ACHL RS15835
gene id: 452863:ACHL_RS15835
uniprot id: B8HFS1
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

452863:ACHL RS07360
gene id: 452863:ACHL_RS07360
uniprot id: B8HG89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

452863:ACHL RS03360
gene id: 452863:ACHL_RS03360
uniprot id: B8HBV9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

452863:ACHL RS12885
gene id: 452863:ACHL_RS12885
uniprot id: B8HCA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

452863:ACHL RS04780
gene id: 452863:ACHL_RS04780
uniprot id: B8HDD6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS14935
gene id: 452863:ACHL_RS14935
uniprot id: B8HEI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

452863:ACHL RS16845
gene id: 452863:ACHL_RS16845
uniprot id: B8HGQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

452863:ACHL RS11300
gene id: 452863:ACHL_RS11300
uniprot id: B8HAB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

452863:ACHL RS06065
gene id: 452863:ACHL_RS06065
uniprot id: B8HET3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

452863:ACHL RS04240
gene id: 452863:ACHL_RS04240
uniprot id: B8HCQ5
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

452863:ACHL RS13800
gene id: 452863:ACHL_RS13800
uniprot id: B8HD52
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

452863:ACHL RS19340
gene id: 452863:ACHL_RS19340
uniprot id: B8H806
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

452863:ACHL RS04875
gene id: 452863:ACHL_RS04875
uniprot id: B8HDF7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

452863:ACHL RS10870
gene id: 452863:ACHL_RS10870
uniprot id: B8HA33
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

452863:ACHL RS04880
gene id: 452863:ACHL_RS04880
uniprot id: B8HDF8
names: Similarity
messages: Belongs to the TPP enzyme family.

452863:ACHL RS12750
gene id: 452863:ACHL_RS12750
uniprot id: B8HC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS13885
gene id: 452863:ACHL_RS13885
uniprot id: B8HD70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

452863:ACHL RS12515
gene id: 452863:ACHL_RS12515
uniprot id: B8HBQ3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452863:ACHL RS09185
gene id: 452863:ACHL_RS09185
uniprot id: B8H7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

452863:ACHL RS20975
gene id: 452863:ACHL_RS20975
uniprot id: B8HI64
names: Similarity
messages: Belongs to the GSP E family.

452863:ACHL RS16400
gene id: 452863:ACHL_RS16400
uniprot id: B8HG31
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

452863:ACHL RS13345
gene id: 452863:ACHL_RS13345
uniprot id: B8HCJ0
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS02505
gene id: 452863:ACHL_RS02505
uniprot id: B8HAP3
names: Similarity
messages: Belongs to the HIBADH-related family.

452863:ACHL RS08625
gene id: 452863:ACHL_RS08625
uniprot id: B8H6W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

452863:ACHL RS12430
gene id: 452863:ACHL_RS12430
uniprot id: B8HBN8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452863:ACHL RS16045
gene id: 452863:ACHL_RS16045
uniprot id: B8HFW3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

452863:ACHL RS14205
gene id: 452863:ACHL_RS14205
uniprot id: B8HDQ8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

452863:ACHL RS17240
gene id: 452863:ACHL_RS17240
uniprot id: B8HHA6
names: Subunit
messages: Homotetramer.

452863:ACHL RS06795
gene id: 452863:ACHL_RS06795
uniprot id: B8HFK2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

452863:ACHL RS02090
gene id: 452863:ACHL_RS02090
uniprot id: B8HAG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS21010
gene id: 452863:ACHL_RS21010
uniprot id: B8HI71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS09670
gene id: 452863:ACHL_RS09670
uniprot id: B8H8L5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

452863:ACHL RS07640
gene id: 452863:ACHL_RS07640
uniprot id: B8HGE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS04715
gene id: 452863:ACHL_RS04715
uniprot id: B8HDC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

452863:ACHL RS07730
gene id: 452863:ACHL_RS07730
uniprot id: B8HGG0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

452863:ACHL RS10830
gene id: 452863:ACHL_RS10830
uniprot id: B8HA25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

452863:ACHL RS13540
gene id: 452863:ACHL_RS13540
uniprot id: B8HCZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

452863:ACHL RS01950
gene id: 452863:ACHL_RS01950
uniprot id: B8HA10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

452863:ACHL RS01755
gene id: 452863:ACHL_RS01755
uniprot id: B8H9X1
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS07960
gene id: 452863:ACHL_RS07960
uniprot id: B8HGX7
names: Similarity
messages: Belongs to the YggT family.

452863:ACHL RS09115
gene id: 452863:ACHL_RS09115
uniprot id: B8H7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

452863:ACHL RS03560
gene id: 452863:ACHL_RS03560
uniprot id: B8HBZ9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

452863:ACHL RS03330
gene id: 452863:ACHL_RS03330
uniprot id: B8HBV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

452863:ACHL RS13765
gene id: 452863:ACHL_RS13765
uniprot id: B8HD45
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

452863:ACHL RS17290
gene id: 452863:ACHL_RS17290
uniprot id: B8HHB7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

452863:ACHL RS15575
gene id: 452863:ACHL_RS15575
uniprot id: B8HF93
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

452863:ACHL RS06110
gene id: 452863:ACHL_RS06110
uniprot id: B8HEU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS12805
gene id: 452863:ACHL_RS12805
uniprot id: B8HC84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

452863:ACHL RS17585
gene id: 452863:ACHL_RS17585
uniprot id: B8HHH5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452863:ACHL RS16530
gene id: 452863:ACHL_RS16530
uniprot id: B8HGI4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS19565
gene id: 452863:ACHL_RS19565
uniprot id: B8H8V9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

452863:ACHL RS08630
gene id: 452863:ACHL_RS08630
uniprot id: B8H6X0
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS14640
gene id: 452863:ACHL_RS14640
uniprot id: B8HEB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS18765
gene id: 452863:ACHL_RS18765
uniprot id: B8H794
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452863:ACHL RS17010
gene id: 452863:ACHL_RS17010
uniprot id: B8HGT4
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

452863:ACHL RS13565
gene id: 452863:ACHL_RS13565
uniprot id: B8HD04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

452863:ACHL RS07250
gene id: 452863:ACHL_RS07250
uniprot id: B8HG68
names: Similarity
messages: Belongs to the peptidase M16 family.

452863:ACHL RS06970
gene id: 452863:ACHL_RS06970
uniprot id: B8HFN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

452863:ACHL RS16885
gene id: 452863:ACHL_RS16885
uniprot id: B8HGQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS15195
gene id: 452863:ACHL_RS15195
uniprot id: B8HF17
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

452863:ACHL RS10475
gene id: 452863:ACHL_RS10475
uniprot id: B8H9I1
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

452863:ACHL RS01130
gene id: 452863:ACHL_RS01130
uniprot id: B8H968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

452863:ACHL RS05270
gene id: 452863:ACHL_RS05270
uniprot id: B8HE06
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS03710
gene id: 452863:ACHL_RS03710
uniprot id: B8HC29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

452863:ACHL RS13605
gene id: 452863:ACHL_RS13605
uniprot id: B8HD13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

452863:ACHL RS19325
gene id: 452863:ACHL_RS19325
uniprot id: B8H803
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

452863:ACHL RS13830
gene id: 452863:ACHL_RS13830
uniprot id: B8HD58
names: Similarity
messages: Belongs to the UPF0336 family.

452863:ACHL RS04435
gene id: 452863:ACHL_RS04435
uniprot id: B8HCU0
names: Similarity
messages: Belongs to the Dps family.

452863:ACHL RS13445
gene id: 452863:ACHL_RS13445
uniprot id: B8HCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS12740
gene id: 452863:ACHL_RS12740
uniprot id: B8HC71
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

452863:ACHL RS09210
gene id: 452863:ACHL_RS09210
uniprot id: B8H7M4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

452863:ACHL RS11825
gene id: 452863:ACHL_RS11825
uniprot id: B8HAZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

452863:ACHL RS13505
gene id: 452863:ACHL_RS13505
uniprot id: B8HCZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

452863:ACHL RS07980
gene id: 452863:ACHL_RS07980
uniprot id: B8HGY1
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS13240
gene id: 452863:ACHL_RS13240
uniprot id: B8HCG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

452863:ACHL RS18995
gene id: 452863:ACHL_RS18995
uniprot id: B8H7T9
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

452863:ACHL RS13470
gene id: 452863:ACHL_RS13470
uniprot id: B8HCY5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

452863:ACHL RS08290
gene id: 452863:ACHL_RS08290
uniprot id: B8HH43
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04470
gene id: 452863:ACHL_RS04470
uniprot id: B8HCU7
names: Similarity
messages: Belongs to the FemABX family.

452863:ACHL RS01610
gene id: 452863:ACHL_RS01610
uniprot id: B8H9U1
names: Similarity
messages: Belongs to the peptidase C56 family.

452863:ACHL RS19360
gene id: 452863:ACHL_RS19360
uniprot id: B8H810
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS13485
gene id: 452863:ACHL_RS13485
uniprot id: B8HCY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

452863:ACHL RS19500
gene id: 452863:ACHL_RS19500
uniprot id: B8H838
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

452863:ACHL RS19075
gene id: 452863:ACHL_RS19075
uniprot id: B8H7V3
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

452863:ACHL RS04570
gene id: 452863:ACHL_RS04570
uniprot id: B8HD95
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

452863:ACHL RS11205
gene id: 452863:ACHL_RS11205
uniprot id: B8HA94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

452863:ACHL RS00160
gene id: 452863:ACHL_RS00160
uniprot id: B8H858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS23210
gene id: 452863:ACHL_RS23210
uniprot id: B8HJH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS22595
gene id: 452863:ACHL_RS22595
uniprot id: B8HJ50
names: Similarity
messages: Belongs to the peptidase S24 family.

452863:ACHL RS19700
gene id: 452863:ACHL_RS19700
uniprot id: B8H8Y6
names: Similarity
messages: Belongs to the thioredoxin family.

452863:ACHL RS19015
gene id: 452863:ACHL_RS19015
uniprot id: B8H7U3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

452863:ACHL RS03845
gene id: 452863:ACHL_RS03845
uniprot id: B8HC53
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06845
gene id: 452863:ACHL_RS06845
uniprot id: B8HFL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

452863:ACHL RS11185
gene id: 452863:ACHL_RS11185
uniprot id: B8HA90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

452863:ACHL RS03910
gene id: 452863:ACHL_RS03910
uniprot id: B8HC66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS20820
gene id: 452863:ACHL_RS20820
uniprot id: B8HI32
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

452863:ACHL RS04290
gene id: 452863:ACHL_RS04290
uniprot id: B8HCR5
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

452863:ACHL RS08620
gene id: 452863:ACHL_RS08620
uniprot id: B8H6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

452863:ACHL RS02665
gene id: 452863:ACHL_RS02665
uniprot id: B8HB51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

452863:ACHL RS06030
gene id: 452863:ACHL_RS06030
uniprot id: B8HES6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

452863:ACHL RS15155
gene id: 452863:ACHL_RS15155
uniprot id: B8HEN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS12455
gene id: 452863:ACHL_RS12455
uniprot id: B8HBP3
names: Similarity
messages: Belongs to the peptidase S1C family.

452863:ACHL RS09885
gene id: 452863:ACHL_RS09885
uniprot id: B8H8Q8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

452863:ACHL RS05780
gene id: 452863:ACHL_RS05780
uniprot id: B8HEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

452863:ACHL RS04175
gene id: 452863:ACHL_RS04175
uniprot id: B8HCP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

452863:ACHL RS05915
gene id: 452863:ACHL_RS05915
uniprot id: B8HEQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

452863:ACHL RS05020
gene id: 452863:ACHL_RS05020
uniprot id: B8HDI5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

452863:ACHL RS23065
gene id: 452863:ACHL_RS23065
uniprot id: B8HJE8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

452863:ACHL RS07965
gene id: 452863:ACHL_RS07965
uniprot id: B8HGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

452863:ACHL RS10070
gene id: 452863:ACHL_RS10070
uniprot id: B8H8U5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

452863:ACHL RS07420
gene id: 452863:ACHL_RS07420
uniprot id: B8HGA1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

452863:ACHL RS07940
gene id: 452863:ACHL_RS07940
uniprot id: B8HGX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

452863:ACHL RS02125
gene id: 452863:ACHL_RS02125
uniprot id: B8HAG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

452863:ACHL RS07075
gene id: 452863:ACHL_RS07075
uniprot id: B8HFQ7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

452863:ACHL RS03635
gene id: 452863:ACHL_RS03635
uniprot id: B8HC14
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS05535
gene id: 452863:ACHL_RS05535
uniprot id: B8HE59
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

452863:ACHL RS02275
gene id: 452863:ACHL_RS02275
uniprot id: B8HAJ8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452863:ACHL RS09970
gene id: 452863:ACHL_RS09970
uniprot id: B8H8S5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

452863:ACHL RS17150
gene id: 452863:ACHL_RS17150
uniprot id: B8HH88
names: Similarity
messages: Belongs to the thymidylate kinase family.

452863:ACHL RS06895
gene id: 452863:ACHL_RS06895
uniprot id: B8HFM3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

452863:ACHL RS05055
gene id: 452863:ACHL_RS05055
uniprot id: B8HDJ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS18850
gene id: 452863:ACHL_RS18850
uniprot id: B8H7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

452863:ACHL RS17700
gene id: 452863:ACHL_RS17700
uniprot id: B8H6G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS01055
gene id: 452863:ACHL_RS01055
uniprot id: B8H953
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS19235
gene id: 452863:ACHL_RS19235
uniprot id: B8H7Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS03290
gene id: 452863:ACHL_RS03290
uniprot id: B8HBH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

452863:ACHL RS12785
gene id: 452863:ACHL_RS12785
uniprot id: B8HC80
names: Similarity
messages: Belongs to the citrate synthase family.

452863:ACHL RS15125
gene id: 452863:ACHL_RS15125
uniprot id: B8HEM6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452863:ACHL RS13610
gene id: 452863:ACHL_RS13610
uniprot id: B8HD14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

452863:ACHL RS13280
gene id: 452863:ACHL_RS13280
uniprot id: B8HCH7
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04070
gene id: 452863:ACHL_RS04070
uniprot id: B8HCM5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

452863:ACHL RS20920
gene id: 452863:ACHL_RS20920
uniprot id: B8HI52
names: Similarity
messages: Belongs to the GSP E family.

452863:ACHL RS07375
gene id: 452863:ACHL_RS07375
uniprot id: B8HG92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

452863:ACHL RS18665
gene id: 452863:ACHL_RS18665
uniprot id: B8H774
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

452863:ACHL RS13600
gene id: 452863:ACHL_RS13600
uniprot id: B8HD12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

452863:ACHL RS07650
gene id: 452863:ACHL_RS07650
uniprot id: B8HGE4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS18860
gene id: 452863:ACHL_RS18860
uniprot id: B8H7B3
names: Similarity
messages: Belongs to the AAA ATPase family.

452863:ACHL RS02775
gene id: 452863:ACHL_RS02775
uniprot id: B8HB73
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01075
gene id: 452863:ACHL_RS01075
uniprot id: B8H957
names: Similarity
messages: Belongs to the HIBADH-related family.

452863:ACHL RS00485
gene id: 452863:ACHL_RS00485
uniprot id: B8H8C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

452863:ACHL RS13560
gene id: 452863:ACHL_RS13560
uniprot id: B8HD03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

452863:ACHL RS02165
gene id: 452863:ACHL_RS02165
uniprot id: B8HAH6
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS06470
gene id: 452863:ACHL_RS06470
uniprot id: B8HFD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

452863:ACHL RS15940
gene id: 452863:ACHL_RS15940
uniprot id: B8HFU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

452863:ACHL RS06215
gene id: 452863:ACHL_RS06215
uniprot id: B8HEW2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

452863:ACHL RS02080
gene id: 452863:ACHL_RS02080
uniprot id: B8HAF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

452863:ACHL RS19100
gene id: 452863:ACHL_RS19100
uniprot id: B8H7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS01410
gene id: 452863:ACHL_RS01410
uniprot id: B8H9Q1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

452863:ACHL RS13480
gene id: 452863:ACHL_RS13480
uniprot id: B8HCY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

452863:ACHL RS00515
gene id: 452863:ACHL_RS00515
uniprot id: B8H8D0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS08150
gene id: 452863:ACHL_RS08150
uniprot id: B8HH16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

452863:ACHL RS12065
gene id: 452863:ACHL_RS12065
uniprot id: B8HB39
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

452863:ACHL RS18785
gene id: 452863:ACHL_RS18785
uniprot id: B8H798
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

452863:ACHL RS13685
gene id: 452863:ACHL_RS13685
uniprot id: B8HD28
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452863:ACHL RS09955
gene id: 452863:ACHL_RS09955
uniprot id: B8H8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

452863:ACHL RS09845
gene id: 452863:ACHL_RS09845
uniprot id: B8H8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

452863:ACHL RS13390
gene id: 452863:ACHL_RS13390
uniprot id: B8HCW9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS14950
gene id: 452863:ACHL_RS14950
uniprot id: B8HEJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

452863:ACHL RS18020
gene id: 452863:ACHL_RS18020
uniprot id: B8H6M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS04720
gene id: 452863:ACHL_RS04720
uniprot id: B8HDC4
names: Similarity
messages: Belongs to the AHA1 family.

452863:ACHL RS00965
gene id: 452863:ACHL_RS00965
uniprot id: B8H936
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

452863:ACHL RS02465
gene id: 452863:ACHL_RS02465
uniprot id: B8HAN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS05375
gene id: 452863:ACHL_RS05375
uniprot id: B8HE24
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS05130
gene id: 452863:ACHL_RS05130
uniprot id: B8HDK7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

452863:ACHL RS13715
gene id: 452863:ACHL_RS13715
uniprot id: B8HD34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS02840
gene id: 452863:ACHL_RS02840
uniprot id: B8HB86
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452863:ACHL RS05865
gene id: 452863:ACHL_RS05865
uniprot id: B8HEP2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

452863:ACHL RS11895
gene id: 452863:ACHL_RS11895
uniprot id: B8HB05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

452863:ACHL RS14485
gene id: 452863:ACHL_RS14485
uniprot id: B8HDW4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

452863:ACHL RS14860
gene id: 452863:ACHL_RS14860
uniprot id: B8HEH2
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

452863:ACHL RS06925
gene id: 452863:ACHL_RS06925
uniprot id: B8HFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS09930
gene id: 452863:ACHL_RS09930
uniprot id: B8H8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

452863:ACHL RS10090
gene id: 452863:ACHL_RS10090
uniprot id: B8H8U9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

452863:ACHL RS23050
gene id: 452863:ACHL_RS23050
uniprot id: B8HJE5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

452863:ACHL RS19645
gene id: 452863:ACHL_RS19645
uniprot id: B8H8X4
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04385
gene id: 452863:ACHL_RS04385
uniprot id: B8HCT1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

452863:ACHL RS13420
gene id: 452863:ACHL_RS13420
uniprot id: B8HCX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

452863:ACHL RS06385
gene id: 452863:ACHL_RS06385
uniprot id: B8HEZ6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS05525
gene id: 452863:ACHL_RS05525
uniprot id: B8HE57
names: Similarity
messages: Belongs to the YciI family.

452863:ACHL RS06310
gene id: 452863:ACHL_RS06310
uniprot id: B8HEY1
names: Similarity
messages: Belongs to the FemABX family.

452863:ACHL RS05875
gene id: 452863:ACHL_RS05875
uniprot id: B8HEP5
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

452863:ACHL RS12445
gene id: 452863:ACHL_RS12445
uniprot id: B8HBP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

452863:ACHL RS23430
gene id: 452863:ACHL_RS23430
uniprot id: B8HEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

452863:ACHL RS16560
gene id: 452863:ACHL_RS16560
uniprot id: B8HGJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

452863:ACHL RS06320
gene id: 452863:ACHL_RS06320
uniprot id: B8HEY3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452863:ACHL RS02295
gene id: 452863:ACHL_RS02295
uniprot id: B8HAK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS11595
gene id: 452863:ACHL_RS11595
uniprot id: B8HAU5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

452863:ACHL RS16510
gene id: 452863:ACHL_RS16510
uniprot id: B8HGI0
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS06100
gene id: 452863:ACHL_RS06100
uniprot id: B8HEU0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

452863:ACHL RS04085
gene id: 452863:ACHL_RS04085
uniprot id: B8HCM7
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS09225
gene id: 452863:ACHL_RS09225
uniprot id: B8H7M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

452863:ACHL RS09475
gene id: 452863:ACHL_RS09475
uniprot id: B8H7S5
names: Similarity
messages: Belongs to the peptidase M1 family.

452863:ACHL RS00015
gene id: 452863:ACHL_RS00015
uniprot id: B8H7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

452863:ACHL RS12015
gene id: 452863:ACHL_RS12015
uniprot id: B8HB29
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS16445
gene id: 452863:ACHL_RS16445
uniprot id: B8HG40
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

452863:ACHL RS07165
gene id: 452863:ACHL_RS07165
uniprot id: B8HG52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

452863:ACHL RS14010
gene id: 452863:ACHL_RS14010
uniprot id: B8HD93
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12665
gene id: 452863:ACHL_RS12665
uniprot id: B8HBT3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

452863:ACHL RS13220
gene id: 452863:ACHL_RS13220
uniprot id: B8HCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

452863:ACHL RS11495
gene id: 452863:ACHL_RS11495
uniprot id: B8HAS7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

452863:ACHL RS10970
gene id: 452863:ACHL_RS10970
uniprot id: B8HA50
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452863:ACHL RS18265
gene id: 452863:ACHL_RS18265
uniprot id: B8H6S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

452863:ACHL RS07515
gene id: 452863:ACHL_RS07515
uniprot id: B8HGC0
names: Similarity
messages: Belongs to the peptidase M1 family.

452863:ACHL RS17450
gene id: 452863:ACHL_RS17450
uniprot id: B8HHE8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

452863:ACHL RS01315
gene id: 452863:ACHL_RS01315
uniprot id: B8H9A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

452863:ACHL RS18160
gene id: 452863:ACHL_RS18160
uniprot id: B8H6Q4
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS09685
gene id: 452863:ACHL_RS09685
uniprot id: B8H8L8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

452863:ACHL RS03125
gene id: 452863:ACHL_RS03125
uniprot id: B8HBD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS16240
gene id: 452863:ACHL_RS16240
uniprot id: B8HG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

452863:ACHL RS00615
gene id: 452863:ACHL_RS00615
uniprot id: B8H8F0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

452863:ACHL RS04475
gene id: 452863:ACHL_RS04475
uniprot id: B8HCU8
names: Similarity
messages: Belongs to the FemABX family.

452863:ACHL RS19275
gene id: 452863:ACHL_RS19275
uniprot id: B8H7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

452863:ACHL RS11500
gene id: 452863:ACHL_RS11500
uniprot id: B8HAS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

452863:ACHL RS02180
gene id: 452863:ACHL_RS02180
uniprot id: B8HAH9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS03420
gene id: 452863:ACHL_RS03420
uniprot id: B8HBX2
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

452863:ACHL RS13525
gene id: 452863:ACHL_RS13525
uniprot id: B8HCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

452863:ACHL RS15865
gene id: 452863:ACHL_RS15865
uniprot id: B8HFS7
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS08170
gene id: 452863:ACHL_RS08170
uniprot id: B8HH20
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

452863:ACHL RS19045
gene id: 452863:ACHL_RS19045
uniprot id: B8H7U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS17690
gene id: 452863:ACHL_RS17690
uniprot id: B8H6G1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

452863:ACHL RS06635
gene id: 452863:ACHL_RS06635
uniprot id: B8HFH0
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS09120
gene id: 452863:ACHL_RS09120
uniprot id: B8H7K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

452863:ACHL RS08010
gene id: 452863:ACHL_RS08010
uniprot id: B8HGY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

452863:ACHL RS06935
gene id: 452863:ACHL_RS06935
uniprot id: B8HFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

452863:ACHL RS14140
gene id: 452863:ACHL_RS14140
uniprot id: B8HDP6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS05975
gene id: 452863:ACHL_RS05975
uniprot id: B8HER5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

452863:ACHL RS13495
gene id: 452863:ACHL_RS13495
uniprot id: B8HCZ0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

452863:ACHL RS08465
gene id: 452863:ACHL_RS08465
uniprot id: B8H6U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

452863:ACHL RS08425
gene id: 452863:ACHL_RS08425
uniprot id: B8HH64
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

452863:ACHL RS10700
gene id: 452863:ACHL_RS10700
uniprot id: B8H9M4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

452863:ACHL RS05550
gene id: 452863:ACHL_RS05550
uniprot id: B8HE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS15045
gene id: 452863:ACHL_RS15045
uniprot id: B8HEL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

452863:ACHL RS09205
gene id: 452863:ACHL_RS09205
uniprot id: B8H7M3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

452863:ACHL RS05700
gene id: 452863:ACHL_RS05700
uniprot id: B8HE91
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

452863:ACHL RS11195
gene id: 452863:ACHL_RS11195
uniprot id: B8HA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

452863:ACHL RS11885
gene id: 452863:ACHL_RS11885
uniprot id: B8HB03
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

452863:ACHL RS12910
gene id: 452863:ACHL_RS12910
uniprot id: B8HCA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS08305
gene id: 452863:ACHL_RS08305
uniprot id: B8HH46
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452863:ACHL RS10605
gene id: 452863:ACHL_RS10605
uniprot id: B8H9K7
names: Similarity
messages: Belongs to the PspA/IM30 family.

452863:ACHL RS22545
gene id: 452863:ACHL_RS22545
uniprot id: B8HJ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

452863:ACHL RS07770
gene id: 452863:ACHL_RS07770
uniprot id: B8HGG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

452863:ACHL RS16955
gene id: 452863:ACHL_RS16955
uniprot id: B8HGS3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS14095
gene id: 452863:ACHL_RS14095
uniprot id: B8HDN7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

452863:ACHL RS17225
gene id: 452863:ACHL_RS17225
uniprot id: B8HHA3
names: Similarity
messages: Belongs to the HIBADH-related family.

452863:ACHL RS07685
gene id: 452863:ACHL_RS07685
uniprot id: B8HGF1
names: Similarity
messages: Belongs to the PrpD family.

452863:ACHL RS12450
gene id: 452863:ACHL_RS12450
uniprot id: B8HBP2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

452863:ACHL RS10420
gene id: 452863:ACHL_RS10420
uniprot id: B8H9H3
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS13570
gene id: 452863:ACHL_RS13570
uniprot id: B8HD05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

452863:ACHL RS08190
gene id: 452863:ACHL_RS08190
uniprot id: B8HH24
names: Similarity
messages: Belongs to the thymidine kinase family.

452863:ACHL RS10560
gene id: 452863:ACHL_RS10560
uniprot id: B8H9J7
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

452863:ACHL RS17735
gene id: 452863:ACHL_RS17735
uniprot id: B8H6H0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

452863:ACHL RS15065
gene id: 452863:ACHL_RS15065
uniprot id: B8HEL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

452863:ACHL RS18005
gene id: 452863:ACHL_RS18005
uniprot id: B8H6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GcvT family.
messages: Cytoplasm

452863:ACHL RS10885
gene id: 452863:ACHL_RS10885
uniprot id: B8HA36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

452863:ACHL RS22670
gene id: 452863:ACHL_RS22670
uniprot id: B8HJ65
names: Function
names: Similarity
messages: Belongs to the MerB family.
messages: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.

452863:ACHL RS02570
gene id: 452863:ACHL_RS02570
uniprot id: B8HAQ6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13575
gene id: 452863:ACHL_RS13575
uniprot id: B8HD06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

452863:ACHL RS14965
gene id: 452863:ACHL_RS14965
uniprot id: B8HEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

452863:ACHL RS11140
gene id: 452863:ACHL_RS11140
uniprot id: B8HA82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

452863:ACHL RS13190
gene id: 452863:ACHL_RS13190
uniprot id: B8HCF9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

452863:ACHL RS18145
gene id: 452863:ACHL_RS18145
uniprot id: B8H6Q1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

452863:ACHL RS10795
gene id: 452863:ACHL_RS10795
uniprot id: B8H9P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

452863:ACHL RS04380
gene id: 452863:ACHL_RS04380
uniprot id: B8HCT0
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

452863:ACHL RS09125
gene id: 452863:ACHL_RS09125
uniprot id: B8H7K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

452863:ACHL RS17430
gene id: 452863:ACHL_RS17430
uniprot id: B8HHE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

452863:ACHL RS01720
gene id: 452863:ACHL_RS01720
uniprot id: B8H9W4
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

452863:ACHL RS11035
gene id: 452863:ACHL_RS11035
uniprot id: B8HA62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

452863:ACHL RS15080
gene id: 452863:ACHL_RS15080
uniprot id: B8HEL7
names: Similarity
messages: Belongs to the bacterial flagellin family.

452863:ACHL RS09295
gene id: 452863:ACHL_RS09295
uniprot id: B8H7P1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

452863:ACHL RS04110
gene id: 452863:ACHL_RS04110
uniprot id: B8HCN2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06090
gene id: 452863:ACHL_RS06090
uniprot id: B8HET8
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS07380
gene id: 452863:ACHL_RS07380
uniprot id: B8HG93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS11590
gene id: 452863:ACHL_RS11590
uniprot id: B8HAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

452863:ACHL RS05080
gene id: 452863:ACHL_RS05080
uniprot id: B8HDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

452863:ACHL RS08035
gene id: 452863:ACHL_RS08035
uniprot id: B8HGZ3
names: Similarity
messages: Belongs to the glutamine synthetase family.

452863:ACHL RS17900
gene id: 452863:ACHL_RS17900
uniprot id: B8H6K2
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

452863:ACHL RS11130
gene id: 452863:ACHL_RS11130
uniprot id: B8HA80
names: Similarity
messages: Belongs to the CdaR family.

452863:ACHL RS14635
gene id: 452863:ACHL_RS14635
uniprot id: B8HEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS11380
gene id: 452863:ACHL_RS11380
uniprot id: B8HAC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

452863:ACHL RS06415
gene id: 452863:ACHL_RS06415
uniprot id: B8HF02
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS00905
gene id: 452863:ACHL_RS00905
uniprot id: B8H925
names: Similarity
messages: Belongs to the peptidase M1 family.

452863:ACHL RS06685
gene id: 452863:ACHL_RS06685
uniprot id: B8HFI0
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

452863:ACHL RS10980
gene id: 452863:ACHL_RS10980
uniprot id: B8HA52
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

452863:ACHL RS12570
gene id: 452863:ACHL_RS12570
uniprot id: B8HBR4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

452863:ACHL RS05990
gene id: 452863:ACHL_RS05990
uniprot id: B8HER8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452863:ACHL RS14845
gene id: 452863:ACHL_RS14845
uniprot id: B8HEG9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

452863:ACHL RS13640
gene id: 452863:ACHL_RS13640
uniprot id: B8HD20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

452863:ACHL RS14870
gene id: 452863:ACHL_RS14870
uniprot id: B8HEH5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

452863:ACHL RS01810
gene id: 452863:ACHL_RS01810
uniprot id: B8H9Y2
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS05035
gene id: 452863:ACHL_RS05035
uniprot id: B8HDI8
names: Similarity
messages: Belongs to the acylphosphatase family.

452863:ACHL RS06785
gene id: 452863:ACHL_RS06785
uniprot id: B8HFK0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

452863:ACHL RS09215
gene id: 452863:ACHL_RS09215
uniprot id: B8H7M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

452863:ACHL RS08120
gene id: 452863:ACHL_RS08120
uniprot id: B8HH10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

452863:ACHL RS07710
gene id: 452863:ACHL_RS07710
uniprot id: B8HGF6
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS07860
gene id: 452863:ACHL_RS07860
uniprot id: B8HGV7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

452863:ACHL RS19305
gene id: 452863:ACHL_RS19305
uniprot id: B8H7Z9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452863:ACHL RS04260
gene id: 452863:ACHL_RS04260
uniprot id: B8HCQ9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

452863:ACHL RS02965
gene id: 452863:ACHL_RS02965
uniprot id: B8HBB1
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12230
gene id: 452863:ACHL_RS12230
uniprot id: B8HBJ8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

452863:ACHL RS17955
gene id: 452863:ACHL_RS17955
uniprot id: B8H6L3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

452863:ACHL RS22350
gene id: 452863:ACHL_RS22350
uniprot id: B8HIZ9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS00520
gene id: 452863:ACHL_RS00520
uniprot id: B8H8D1
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS00770
gene id: 452863:ACHL_RS00770
uniprot id: B8H8Z7
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS07120
gene id: 452863:ACHL_RS07120
uniprot id: B8HG43
names: Similarity
messages: Belongs to the YciI family.

452863:ACHL RS07880
gene id: 452863:ACHL_RS07880
uniprot id: B8HGW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

452863:ACHL RS01035
gene id: 452863:ACHL_RS01035
uniprot id: B8H949
names: Similarity
messages: Belongs to the thioredoxin family.

452863:ACHL RS19295
gene id: 452863:ACHL_RS19295
uniprot id: B8H7Z7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

452863:ACHL RS13620
gene id: 452863:ACHL_RS13620
uniprot id: B8HD16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

452863:ACHL RS06605
gene id: 452863:ACHL_RS06605
uniprot id: B8HFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

452863:ACHL RS13585
gene id: 452863:ACHL_RS13585
uniprot id: B8HD08
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

452863:ACHL RS06195
gene id: 452863:ACHL_RS06195
uniprot id: B8HEV8
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

452863:ACHL RS04935
gene id: 452863:ACHL_RS04935
uniprot id: B8HDG9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS11385
gene id: 452863:ACHL_RS11385
uniprot id: B8HAC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

452863:ACHL RS03145
gene id: 452863:ACHL_RS03145
uniprot id: B8HBE2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

452863:ACHL RS08210
gene id: 452863:ACHL_RS08210
uniprot id: B8HH28
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

452863:ACHL RS08045
gene id: 452863:ACHL_RS08045
uniprot id: B8HGZ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

452863:ACHL RS17645
gene id: 452863:ACHL_RS17645
uniprot id: B8HHI7
names: Similarity
messages: Belongs to the glutamate synthase family.

452863:ACHL RS07145
gene id: 452863:ACHL_RS07145
uniprot id: B8HG48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS16330
gene id: 452863:ACHL_RS16330
uniprot id: B8HG18
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

452863:ACHL RS07455
gene id: 452863:ACHL_RS07455
uniprot id: B8HGA9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

452863:ACHL RS11610
gene id: 452863:ACHL_RS11610
uniprot id: B8HAU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

452863:ACHL RS06500
gene id: 452863:ACHL_RS06500
uniprot id: B8HFE5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

452863:ACHL RS10430
gene id: 452863:ACHL_RS10430
uniprot id: B8H9H5
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS00925
gene id: 452863:ACHL_RS00925
uniprot id: B8H929
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS15635
gene id: 452863:ACHL_RS15635
uniprot id: B8HFA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS16435
gene id: 452863:ACHL_RS16435
uniprot id: B8HG38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS04835
gene id: 452863:ACHL_RS04835
uniprot id: B8HDE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

452863:ACHL RS12130
gene id: 452863:ACHL_RS12130
uniprot id: B8HBH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

452863:ACHL RS16345
gene id: 452863:ACHL_RS16345
uniprot id: B8HG21
names: Similarity
messages: Belongs to the peptidase S51 family.

452863:ACHL RS00695
gene id: 452863:ACHL_RS00695
uniprot id: B8H8G7
names: Similarity
messages: Belongs to the TPP enzyme family.

452863:ACHL RS15460
gene id: 452863:ACHL_RS15460
uniprot id: B8HF70
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS17170
gene id: 452863:ACHL_RS17170
uniprot id: B8HH92
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

452863:ACHL RS06820
gene id: 452863:ACHL_RS06820
uniprot id: B8HFK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

452863:ACHL RS11515
gene id: 452863:ACHL_RS11515
uniprot id: B8HAT1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS12780
gene id: 452863:ACHL_RS12780
uniprot id: B8HC79
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

452863:ACHL RS01565
gene id: 452863:ACHL_RS01565
uniprot id: B8H9T2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

452863:ACHL RS12110
gene id: 452863:ACHL_RS12110
uniprot id: B8HBH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

452863:ACHL RS15680
gene id: 452863:ACHL_RS15680
uniprot id: B8HFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS15670
gene id: 452863:ACHL_RS15670
uniprot id: B8HFB3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS17485
gene id: 452863:ACHL_RS17485
uniprot id: B8HHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

452863:ACHL RS12510
gene id: 452863:ACHL_RS12510
uniprot id: B8HBQ2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

452863:ACHL RS13215
gene id: 452863:ACHL_RS13215
uniprot id: B8HCG4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

452863:ACHL RS09330
gene id: 452863:ACHL_RS09330
uniprot id: B8H7P8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452863:ACHL RS03695
gene id: 452863:ACHL_RS03695
uniprot id: B8HC26
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452863:ACHL RS06075
gene id: 452863:ACHL_RS06075
uniprot id: B8HET5
names: Similarity
messages: Belongs to the BMP lipoprotein family.

452863:ACHL RS11340
gene id: 452863:ACHL_RS11340
uniprot id: B8HAC0
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

452863:ACHL RS22510
gene id: 452863:ACHL_RS22510
uniprot id: B8HJ32
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

452863:ACHL RS07545
gene id: 452863:ACHL_RS07545
uniprot id: B8HGC6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

452863:ACHL RS14300
gene id: 452863:ACHL_RS14300
uniprot id: B8HDS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS05850
gene id: 452863:ACHL_RS05850
uniprot id: B8HEN9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

452863:ACHL RS19465
gene id: 452863:ACHL_RS19465
uniprot id: B8H831
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13025
gene id: 452863:ACHL_RS13025
uniprot id: B8HCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

452863:ACHL RS10265
gene id: 452863:ACHL_RS10265
uniprot id: B8H9E4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

452863:ACHL RS16740
gene id: 452863:ACHL_RS16740
uniprot id: B8HGM7
names: Similarity
messages: Belongs to the peptidase M20A family.

452863:ACHL RS15520
gene id: 452863:ACHL_RS15520
uniprot id: B8HF82
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS10225
gene id: 452863:ACHL_RS10225
uniprot id: B8H9D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

452863:ACHL RS10810
gene id: 452863:ACHL_RS10810
uniprot id: B8HA21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

452863:ACHL RS08350
gene id: 452863:ACHL_RS08350
uniprot id: B8HH55
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

452863:ACHL RS06035
gene id: 452863:ACHL_RS06035
uniprot id: B8HES7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

452863:ACHL RS02925
gene id: 452863:ACHL_RS02925
uniprot id: B8HBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

452863:ACHL RS01705
gene id: 452863:ACHL_RS01705
uniprot id: B8H9W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS11810
gene id: 452863:ACHL_RS11810
uniprot id: B8HAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

452863:ACHL RS02685
gene id: 452863:ACHL_RS02685
uniprot id: B8HB55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

452863:ACHL RS08540
gene id: 452863:ACHL_RS08540
uniprot id: B8H6V4
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

452863:ACHL RS03740
gene id: 452863:ACHL_RS03740
uniprot id: B8HC35
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452863:ACHL RS05965
gene id: 452863:ACHL_RS05965
uniprot id: B8HER3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

452863:ACHL RS07805
gene id: 452863:ACHL_RS07805
uniprot id: B8HGU6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

452863:ACHL RS10670
gene id: 452863:ACHL_RS10670
uniprot id: B8H9L8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

452863:ACHL RS08665
gene id: 452863:ACHL_RS08665
uniprot id: B8H6X6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS15290
gene id: 452863:ACHL_RS15290
uniprot id: B8HF37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

452863:ACHL RS06980
gene id: 452863:ACHL_RS06980
uniprot id: B8HFN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

452863:ACHL RS12320
gene id: 452863:ACHL_RS12320
uniprot id: B8HBL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

452863:ACHL RS08015
gene id: 452863:ACHL_RS08015
uniprot id: B8HGY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

452863:ACHL RS03955
gene id: 452863:ACHL_RS03955
uniprot id: B8HCK2
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.

452863:ACHL RS13955
gene id: 452863:ACHL_RS13955
uniprot id: B8HD82
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS17890
gene id: 452863:ACHL_RS17890
uniprot id: B8H6K0
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

452863:ACHL RS20965
gene id: 452863:ACHL_RS20965
uniprot id: B8HI62
names: Similarity
messages: Belongs to the peptidase A24 family.

452863:ACHL RS00165
gene id: 452863:ACHL_RS00165
uniprot id: B8H859
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS18090
gene id: 452863:ACHL_RS18090
uniprot id: B8H6P0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS07170
gene id: 452863:ACHL_RS07170
uniprot id: B8HG53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

452863:ACHL RS01455
gene id: 452863:ACHL_RS01455
uniprot id: B8H9R0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

452863:ACHL RS01875
gene id: 452863:ACHL_RS01875
uniprot id: B8H9Z4
names: Similarity
messages: Belongs to the ribulokinase family.

452863:ACHL RS22960
gene id: 452863:ACHL_RS22960
uniprot id: B8HJC7
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

452863:ACHL RS07815
gene id: 452863:ACHL_RS07815
uniprot id: B8HGU8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452863:ACHL RS11175
gene id: 452863:ACHL_RS11175
uniprot id: B8HA88
names: Similarity
messages: Belongs to the UPF0102 family.

452863:ACHL RS18075
gene id: 452863:ACHL_RS18075
uniprot id: B8H6N7
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

452863:ACHL RS04185
gene id: 452863:ACHL_RS04185
uniprot id: B8HCP5
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

452863:ACHL RS11080
gene id: 452863:ACHL_RS11080
uniprot id: B8HA71
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

452863:ACHL RS04315
gene id: 452863:ACHL_RS04315
uniprot id: B8HCS0
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

452863:ACHL RS03540
gene id: 452863:ACHL_RS03540
uniprot id: B8HBZ5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

452863:ACHL RS17210
gene id: 452863:ACHL_RS17210
uniprot id: B8HHA0
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12650
gene id: 452863:ACHL_RS12650
uniprot id: B8HBT0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS09420
gene id: 452863:ACHL_RS09420
uniprot id: B8H7R4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS01710
gene id: 452863:ACHL_RS01710
uniprot id: B8H9W3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452863:ACHL RS16000
gene id: 452863:ACHL_RS16000
uniprot id: B8HFV4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

452863:ACHL RS03215
gene id: 452863:ACHL_RS03215
uniprot id: B8HBF6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

452863:ACHL RS09335
gene id: 452863:ACHL_RS09335
uniprot id: B8H7P9
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01795
gene id: 452863:ACHL_RS01795
uniprot id: B8H9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

452863:ACHL RS13700
gene id: 452863:ACHL_RS13700
uniprot id: B8HD31
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS09170
gene id: 452863:ACHL_RS09170
uniprot id: B8H7L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

452863:ACHL RS15720
gene id: 452863:ACHL_RS15720
uniprot id: B8HFC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS10845
gene id: 452863:ACHL_RS10845
uniprot id: B8HA28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

452863:ACHL RS23085
gene id: 452863:ACHL_RS23085
uniprot id: B8HJF1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

452863:ACHL RS04530
gene id: 452863:ACHL_RS04530
uniprot id: B8HCV9
names: Similarity
messages: Belongs to the WXG100 family.

452863:ACHL RS10905
gene id: 452863:ACHL_RS10905
uniprot id: B8HA38
names: Similarity
messages: Belongs to the LacAB/RpiB family.

452863:ACHL RS03255
gene id: 452863:ACHL_RS03255
uniprot id: B8HBG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

452863:ACHL RS15210
gene id: 452863:ACHL_RS15210
uniprot id: B8HF20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

452863:ACHL RS06085
gene id: 452863:ACHL_RS06085
uniprot id: B8HET7
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04100
gene id: 452863:ACHL_RS04100
uniprot id: B8HCN0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

452863:ACHL RS16295
gene id: 452863:ACHL_RS16295
uniprot id: B8HG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS02485
gene id: 452863:ACHL_RS02485
uniprot id: B8HAN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

452863:ACHL RS07450
gene id: 452863:ACHL_RS07450
uniprot id: B8HGA8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

452863:ACHL RS08025
gene id: 452863:ACHL_RS08025
uniprot id: B8HGZ1
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

452863:ACHL RS19545
gene id: 452863:ACHL_RS19545
uniprot id: B8H847
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

452863:ACHL RS13490
gene id: 452863:ACHL_RS13490
uniprot id: B8HCY9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

452863:ACHL RS12745
gene id: 452863:ACHL_RS12745
uniprot id: B8HC72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS10165
gene id: 452863:ACHL_RS10165
uniprot id: B8H9C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

452863:ACHL RS15245
gene id: 452863:ACHL_RS15245
uniprot id: B8HF27
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452863:ACHL RS17235
gene id: 452863:ACHL_RS17235
uniprot id: B8HHA5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

452863:ACHL RS07415
gene id: 452863:ACHL_RS07415
uniprot id: B8HGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

452863:ACHL RS02300
gene id: 452863:ACHL_RS02300
uniprot id: B8HAK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

452863:ACHL RS11790
gene id: 452863:ACHL_RS11790
uniprot id: B8HAY4
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS11860
gene id: 452863:ACHL_RS11860
uniprot id: B8HAZ8
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS10405
gene id: 452863:ACHL_RS10405
uniprot id: B8H9H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

452863:ACHL RS10400
gene id: 452863:ACHL_RS10400
uniprot id: B8H9H0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

452863:ACHL RS10460
gene id: 452863:ACHL_RS10460
uniprot id: B8H9I0
names: Subcellular Location Annotation
messages: Cell membrane

452863:ACHL RS07945
gene id: 452863:ACHL_RS07945
uniprot id: B8HGX4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

452863:ACHL RS02595
gene id: 452863:ACHL_RS02595
uniprot id: B8HAR1
names: Similarity
messages: Belongs to the AHA1 family.

452863:ACHL RS07535
gene id: 452863:ACHL_RS07535
uniprot id: B8HGC4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

452863:ACHL RS10105
gene id: 452863:ACHL_RS10105
uniprot id: B8H8V2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

452863:ACHL RS02610
gene id: 452863:ACHL_RS02610
uniprot id: B8HAR4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

452863:ACHL RS07285
gene id: 452863:ACHL_RS07285
uniprot id: B8HG74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

452863:ACHL RS03390
gene id: 452863:ACHL_RS03390
uniprot id: B8HBW6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

452863:ACHL RS13760
gene id: 452863:ACHL_RS13760
uniprot id: B8HD44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

452863:ACHL RS14440
gene id: 452863:ACHL_RS14440
uniprot id: B8HDV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS06220
gene id: 452863:ACHL_RS06220
uniprot id: B8HEW3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS06560
gene id: 452863:ACHL_RS06560
uniprot id: B8HFF6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

452863:ACHL RS14330
gene id: 452863:ACHL_RS14330
uniprot id: B8HDT3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

452863:ACHL RS06650
gene id: 452863:ACHL_RS06650
uniprot id: B8HFH3
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS09245
gene id: 452863:ACHL_RS09245
uniprot id: B8H7N1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS09255
gene id: 452863:ACHL_RS09255
uniprot id: B8H7N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

452863:ACHL RS20235
gene id: 452863:ACHL_RS20235
uniprot id: B8HHR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

452863:ACHL RS13630
gene id: 452863:ACHL_RS13630
uniprot id: B8HD18
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452863:ACHL RS17230
gene id: 452863:ACHL_RS17230
uniprot id: B8HHA4
names: Similarity
messages: Belongs to the TPP enzyme family.

452863:ACHL RS09130
gene id: 452863:ACHL_RS09130
uniprot id: B8H7K8
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS12575
gene id: 452863:ACHL_RS12575
uniprot id: B8HBR5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

452863:ACHL RS03245
gene id: 452863:ACHL_RS03245
uniprot id: B8HBG2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

452863:ACHL RS07840
gene id: 452863:ACHL_RS07840
uniprot id: B8HGV3
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

452863:ACHL RS17880
gene id: 452863:ACHL_RS17880
uniprot id: B8H6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS06965
gene id: 452863:ACHL_RS06965
uniprot id: B8HFN5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

452863:ACHL RS18250
gene id: 452863:ACHL_RS18250
uniprot id: B8H6S2
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS13550
gene id: 452863:ACHL_RS13550
uniprot id: B8HD01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

452863:ACHL RS06975
gene id: 452863:ACHL_RS06975
uniprot id: B8HFN7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS11990
gene id: 452863:ACHL_RS11990
uniprot id: B8HB24
names: Similarity
messages: Belongs to the Fur family.

452863:ACHL RS11055
gene id: 452863:ACHL_RS11055
uniprot id: B8HA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

452863:ACHL RS13670
gene id: 452863:ACHL_RS13670
uniprot id: B8HD26
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

452863:ACHL RS18855
gene id: 452863:ACHL_RS18855
uniprot id: B8H7B2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

452863:ACHL RS16070
gene id: 452863:ACHL_RS16070
uniprot id: B8HFW8
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

452863:ACHL RS11820
gene id: 452863:ACHL_RS11820
uniprot id: B8HAZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

452863:ACHL RS03000
gene id: 452863:ACHL_RS03000
uniprot id: B8HBB8
names: Similarity
messages: Belongs to the universal stress protein A family.

452863:ACHL RS15510
gene id: 452863:ACHL_RS15510
uniprot id: B8HF80
names: Similarity
messages: Belongs to the heat shock protein 70 family.

452863:ACHL RS15555
gene id: 452863:ACHL_RS15555
uniprot id: B8HF89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

452863:ACHL RS18775
gene id: 452863:ACHL_RS18775
uniprot id: B8H796
names: Similarity
messages: Belongs to the UPF0225 family.

452863:ACHL RS03080
gene id: 452863:ACHL_RS03080
uniprot id: B8HBC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

452863:ACHL RS04505
gene id: 452863:ACHL_RS04505
uniprot id: B8HCV4
names: Subcellular Location Annotation
messages: Cytoplasm

452863:ACHL RS16695
gene id: 452863:ACHL_RS16695
uniprot id: B8HGL8
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01960
gene id: 452863:ACHL_RS01960
uniprot id: B8HA12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS08840
gene id: 452863:ACHL_RS08840
uniprot id: B8H7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS08280
gene id: 452863:ACHL_RS08280
uniprot id: B8HH41
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

452863:ACHL RS01570
gene id: 452863:ACHL_RS01570
uniprot id: B8H9T3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

452863:ACHL RS16040
gene id: 452863:ACHL_RS16040
uniprot id: B8HFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

452863:ACHL RS05425
gene id: 452863:ACHL_RS05425
uniprot id: B8HE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

452863:ACHL RS02585
gene id: 452863:ACHL_RS02585
uniprot id: B8HAQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

452863:ACHL RS18620
gene id: 452863:ACHL_RS18620
uniprot id: B8H771
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

452863:ACHL RS03605
gene id: 452863:ACHL_RS03605
uniprot id: B8HC08
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

452863:ACHL RS19330
gene id: 452863:ACHL_RS19330
uniprot id: B8H804
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

452863:ACHL RS08090
gene id: 452863:ACHL_RS08090
uniprot id: B8HH04
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

452863:ACHL RS08000
gene id: 452863:ACHL_RS08000
uniprot id: B8HGY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

452863:ACHL RS07150
gene id: 452863:ACHL_RS07150
uniprot id: B8HG49
names: Similarity
messages: Belongs to the group II decarboxylase family.

452863:ACHL RS02635
gene id: 452863:ACHL_RS02635
uniprot id: B8HAR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

452863:ACHL RS04440
gene id: 452863:ACHL_RS04440
uniprot id: B8HCU1
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS07705
gene id: 452863:ACHL_RS07705
uniprot id: B8HGF5
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS13110
gene id: 452863:ACHL_RS13110
uniprot id: B8HCE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

452863:ACHL RS01045
gene id: 452863:ACHL_RS01045
uniprot id: B8H951
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS15920
gene id: 452863:ACHL_RS15920
uniprot id: B8HFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS10555
gene id: 452863:ACHL_RS10555
uniprot id: B8H9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452863:ACHL RS09465
gene id: 452863:ACHL_RS09465
uniprot id: B8H7S3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

452863:ACHL RS17505
gene id: 452863:ACHL_RS17505
uniprot id: B8HHF9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

452863:ACHL RS09735
gene id: 452863:ACHL_RS09735
uniprot id: B8H8M8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS11510
gene id: 452863:ACHL_RS11510
uniprot id: B8HAT0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

452863:ACHL RS12175
gene id: 452863:ACHL_RS12175
uniprot id: B8HBI7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

452863:ACHL RS00195
gene id: 452863:ACHL_RS00195
uniprot id: B8H865
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452863:ACHL RS10185
gene id: 452863:ACHL_RS10185
uniprot id: B8H9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

452863:ACHL RS01190
gene id: 452863:ACHL_RS01190
uniprot id: B8H981
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

452863:ACHL RS02710
gene id: 452863:ACHL_RS02710
uniprot id: B8HB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

452863:ACHL RS16615
gene id: 452863:ACHL_RS16615
uniprot id: B8HGK2
names: Similarity
messages: Belongs to the DapA family.

452863:ACHL RS06295
gene id: 452863:ACHL_RS06295
uniprot id: B8HEX8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

452863:ACHL RS13180
gene id: 452863:ACHL_RS13180
uniprot id: B8HCF7
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

452863:ACHL RS08525
gene id: 452863:ACHL_RS08525
uniprot id: B8H6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

452863:ACHL RS08110
gene id: 452863:ACHL_RS08110
uniprot id: B8HH08
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS04310
gene id: 452863:ACHL_RS04310
uniprot id: B8HCR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

452863:ACHL RS06450
gene id: 452863:ACHL_RS06450
uniprot id: B8HF09
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

452863:ACHL RS13175
gene id: 452863:ACHL_RS13175
uniprot id: B8HCF6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

452863:ACHL RS12730
gene id: 452863:ACHL_RS12730
uniprot id: B8HBU7
names: Similarity
messages: Belongs to the LOG family.

452863:ACHL RS17865
gene id: 452863:ACHL_RS17865
uniprot id: B8H6J5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

452863:ACHL RS22480
gene id: 452863:ACHL_RS22480
uniprot id: B8HJ26
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

452863:ACHL RS19725
gene id: 452863:ACHL_RS19725
uniprot id: B8H8Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

452863:ACHL RS22415
gene id: 452863:ACHL_RS22415
uniprot id: B8HJ13
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

452863:ACHL RS13290
gene id: 452863:ACHL_RS13290
uniprot id: B8HCH9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

452863:ACHL RS10230
gene id: 452863:ACHL_RS10230
uniprot id: B8H9D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

452863:ACHL RS07225
gene id: 452863:ACHL_RS07225
uniprot id: B8HG63
names: Similarity
messages: Belongs to the ribF family.

452863:ACHL RS01540
gene id: 452863:ACHL_RS01540
uniprot id: B8H9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

452863:ACHL RS12825
gene id: 452863:ACHL_RS12825
uniprot id: B8HC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS03555
gene id: 452863:ACHL_RS03555
uniprot id: B8HBZ8
names: Cofactor
messages: Can also use Mn(2+) ion.

452863:ACHL RS12265
gene id: 452863:ACHL_RS12265
uniprot id: B8HBK5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

452863:ACHL RS10045
gene id: 452863:ACHL_RS10045
uniprot id: B8H8U0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS07735
gene id: 452863:ACHL_RS07735
uniprot id: B8HGG1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

452863:ACHL RS06180
gene id: 452863:ACHL_RS06180
uniprot id: B8HEV5
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS17350
gene id: 452863:ACHL_RS17350
uniprot id: B8HHC8
names: Similarity
messages: Belongs to the GcvT family.

452863:ACHL RS02515
gene id: 452863:ACHL_RS02515
uniprot id: B8HAP5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

452863:ACHL RS17385
gene id: 452863:ACHL_RS17385
uniprot id: B8HHD5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

452863:ACHL RS18440
gene id: 452863:ACHL_RS18440
uniprot id: B8H734
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

452863:ACHL RS05985
gene id: 452863:ACHL_RS05985
uniprot id: B8HER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452863:ACHL RS09815
gene id: 452863:ACHL_RS09815
uniprot id: B8H8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

452863:ACHL RS19280
gene id: 452863:ACHL_RS19280
uniprot id: B8H7Z4
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

452863:ACHL RS15390
gene id: 452863:ACHL_RS15390
uniprot id: B8HF56
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452863:ACHL RS14350
gene id: 452863:ACHL_RS14350
uniprot id: B8HDT7
names: Subcellular Location Annotation
messages: Membrane

452863:ACHL RS01985
gene id: 452863:ACHL_RS01985
uniprot id: B8HA17
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

452863:ACHL RS08475
gene id: 452863:ACHL_RS08475
uniprot id: B8H6U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

452863:ACHL RS10525
gene id: 452863:ACHL_RS10525
uniprot id: B8H9J0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS15225
gene id: 452863:ACHL_RS15225
uniprot id: B8HF23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

452863:ACHL RS16450
gene id: 452863:ACHL_RS16450
uniprot id: B8HGG8
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

452863:ACHL RS14035
gene id: 452863:ACHL_RS14035
uniprot id: B8HDM5
names: Similarity
messages: Belongs to the UPF0234 family.

452863:ACHL RS16735
gene id: 452863:ACHL_RS16735
uniprot id: B8HGM6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452863:ACHL RS09890
gene id: 452863:ACHL_RS09890
uniprot id: B8H8Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

452863:ACHL RS04670
gene id: 452863:ACHL_RS04670
uniprot id: B8HDB5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452863:ACHL RS09310
gene id: 452863:ACHL_RS09310
uniprot id: B8H7P4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

452863:ACHL RS11660
gene id: 452863:ACHL_RS11660
uniprot id: B8HAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

452863:ACHL RS13770
gene id: 452863:ACHL_RS13770
uniprot id: B8HD46
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452863:ACHL RS11095
gene id: 452863:ACHL_RS11095
uniprot id: B8HA74
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452863:ACHL RS08140
gene id: 452863:ACHL_RS08140
uniprot id: B8HH14
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

452863:ACHL RS10755
gene id: 452863:ACHL_RS10755
uniprot id: B8H9N5
names: Similarity
messages: Belongs to the CFA/CMAS family.

452863:ACHL RS18490
gene id: 452863:ACHL_RS18490
uniprot id: B8H744
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452863:ACHL RS15040
gene id: 452863:ACHL_RS15040
uniprot id: B8HEK9
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

452863:ACHL RS01665
gene id: 452863:ACHL_RS01665
uniprot id: B8H9V3
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

452863:ACHL RS09200
gene id: 452863:ACHL_RS09200
uniprot id: B8H7M2
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

452863:ACHL RS02750
gene id: 452863:ACHL_RS02750
uniprot id: B8HB68
names: Similarity
messages: Belongs to the Dps family.

452863:ACHL RS18355
gene id: 452863:ACHL_RS18355
uniprot id: B8H717
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

452863:ACHL RS10930
gene id: 452863:ACHL_RS10930
uniprot id: B8HA43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

452863:ACHL RS11915
gene id: 452863:ACHL_RS11915
uniprot id: B8HB09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

452863:ACHL RS07920
gene id: 452863:ACHL_RS07920
uniprot id: B8HGW9
names: Subcellular Location Annotation
messages: Membrane