452652:KSE RS02665
gene id: 452652:KSE_RS02665
uniprot id: E4N5C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS01965
gene id: 452652:KSE_RS01965
uniprot id: E4N4X5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452652:KSE RS29310
gene id: 452652:KSE_RS29310
uniprot id: E4N0K7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

452652:KSE RS13440
gene id: 452652:KSE_RS13440
uniprot id: E4NBG2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09425
gene id: 452652:KSE_RS09425
uniprot id: E4N962
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS29495
gene id: 452652:KSE_RS29495
uniprot id: E4N0P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS28075
gene id: 452652:KSE_RS28075
uniprot id: E4N0C1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS27350
gene id: 452652:KSE_RS27350
uniprot id: E4NIH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

452652:KSE RS30110
gene id: 452652:KSE_RS30110
uniprot id: E4N119
names: Similarity
messages: Belongs to the phosphohexose mutase family.

452652:KSE RS22755
gene id: 452652:KSE_RS22755
uniprot id: E4NFW8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS00545
gene id: 452652:KSE_RS00545
uniprot id: E4N435
names: Similarity
messages: Belongs to the peptidase S11 family.

452652:KSE RS26895
gene id: 452652:KSE_RS26895
uniprot id: E4NI84
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

452652:KSE RS19195
gene id: 452652:KSE_RS19195
uniprot id: E4MZB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

452652:KSE RS34375
gene id: 452652:KSE_RS34375
uniprot id: E4N3H6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

452652:KSE RS21750
gene id: 452652:KSE_RS21750
uniprot id: E4NFB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

452652:KSE RS25405
gene id: 452652:KSE_RS25405
uniprot id: E4NHE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

452652:KSE RS33020
gene id: 452652:KSE_RS33020
uniprot id: E4N2Q4
names: Similarity
messages: Belongs to the proline racemase family.

452652:KSE RS08860
gene id: 452652:KSE_RS08860
uniprot id: E4N8U7
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS15285
gene id: 452652:KSE_RS15285
uniprot id: E4NCH8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452652:KSE RS05050
gene id: 452652:KSE_RS05050
uniprot id: E4N6P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

452652:KSE RS34000
gene id: 452652:KSE_RS34000
uniprot id: E4N3A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

452652:KSE RS23620
gene id: 452652:KSE_RS23620
uniprot id: E4NGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

452652:KSE RS28645
gene id: 452652:KSE_RS28645
uniprot id: E4N3T0
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

452652:KSE RS27900
gene id: 452652:KSE_RS27900
uniprot id: E4N086
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

452652:KSE RS31395
gene id: 452652:KSE_RS31395
uniprot id: E4N1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

452652:KSE RS24095
gene id: 452652:KSE_RS24095
uniprot id: E4NGN3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

452652:KSE RS36630
gene id: 452652:KSE_RS36630
uniprot id: E4NJL3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS40020
gene id: 452652:KSE_RS40020
uniprot id: E4NCU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

452652:KSE RS28305
gene id: 452652:KSE_RS28305
uniprot id: E4N3L5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

452652:KSE RS15180
gene id: 452652:KSE_RS15180
uniprot id: E4NCF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

452652:KSE RS26630
gene id: 452652:KSE_RS26630
uniprot id: E4NI31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

452652:KSE RS25565
gene id: 452652:KSE_RS25565
uniprot id: E4NHH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

452652:KSE RS14175
gene id: 452652:KSE_RS14175
uniprot id: E4NBV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

452652:KSE RS29820
gene id: 452652:KSE_RS29820
uniprot id: E4N0W2
names: Similarity
messages: Belongs to the DapA family.

452652:KSE RS14370
gene id: 452652:KSE_RS14370
uniprot id: E4NBZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

452652:KSE RS25465
gene id: 452652:KSE_RS25465
uniprot id: E4NHF2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

452652:KSE RS19360
gene id: 452652:KSE_RS19360
uniprot id: E4MZE5
names: Similarity
messages: Belongs to the UPF0232 family.

452652:KSE RS08930
gene id: 452652:KSE_RS08930
uniprot id: E4N8W0
names: Similarity
messages: Belongs to the catalase family.

452652:KSE RS09755
gene id: 452652:KSE_RS09755
uniprot id: E4N9C7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

452652:KSE RS12895
gene id: 452652:KSE_RS12895
uniprot id: E4NB58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

452652:KSE RS04420
gene id: 452652:KSE_RS04420
uniprot id: E4N6C2
names: Similarity
messages: Belongs to the PrpD family.

452652:KSE RS12235
gene id: 452652:KSE_RS12235
uniprot id: E4NAT3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

452652:KSE RS31860
gene id: 452652:KSE_RS31860
uniprot id: E4N222
names: Similarity
messages: Belongs to the peptidase S51 family.

452652:KSE RS08065
gene id: 452652:KSE_RS08065
uniprot id: E4N8E1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

452652:KSE RS27110
gene id: 452652:KSE_RS27110
uniprot id: E4NIC4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

452652:KSE RS29005
gene id: 452652:KSE_RS29005
uniprot id: E4N401
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS07460
gene id: 452652:KSE_RS07460
uniprot id: E4N825
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

452652:KSE RS16715
gene id: 452652:KSE_RS16715
uniprot id: E4NDB2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS21735
gene id: 452652:KSE_RS21735
uniprot id: E4NFB1
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

452652:KSE RS10355
gene id: 452652:KSE_RS10355
uniprot id: E4N9P7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS33310
gene id: 452652:KSE_RS33310
uniprot id: E4N2W2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS25280
gene id: 452652:KSE_RS25280
uniprot id: E4NHB8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS09110
gene id: 452652:KSE_RS09110
uniprot id: E4N8Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS12985
gene id: 452652:KSE_RS12985
uniprot id: E4NB75
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS01080
gene id: 452652:KSE_RS01080
uniprot id: E4N4E3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

452652:KSE RS15685
gene id: 452652:KSE_RS15685
uniprot id: E4NCQ7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

452652:KSE RS18960
gene id: 452652:KSE_RS18960
uniprot id: E4MZ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

452652:KSE RS10580
gene id: 452652:KSE_RS10580
uniprot id: E4N9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

452652:KSE RS26585
gene id: 452652:KSE_RS26585
uniprot id: E4NI22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

452652:KSE RS05705
gene id: 452652:KSE_RS05705
uniprot id: E4N725
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

452652:KSE RS15240
gene id: 452652:KSE_RS15240
uniprot id: E4NCG9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS38585
gene id: 452652:KSE_RS38585
uniprot id: E4NEA6
names: Similarity
messages: Belongs to the peptidase C40 family.

452652:KSE RS12540
gene id: 452652:KSE_RS12540
uniprot id: E4NAZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

452652:KSE RS27380
gene id: 452652:KSE_RS27380
uniprot id: E4NIH8
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

452652:KSE RS25105
gene id: 452652:KSE_RS25105
uniprot id: E4NH84
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

452652:KSE RS10905
gene id: 452652:KSE_RS10905
uniprot id: E4NA08
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

452652:KSE RS12835
gene id: 452652:KSE_RS12835
uniprot id: E4NB46
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

452652:KSE RS25210
gene id: 452652:KSE_RS25210
uniprot id: E4NHA4
names: Similarity
messages: Belongs to the LOG family.

452652:KSE RS02085
gene id: 452652:KSE_RS02085
uniprot id: E4N500
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

452652:KSE RS23915
gene id: 452652:KSE_RS23915
uniprot id: E4NGJ5
names: Similarity
messages: Belongs to the LOG family.

452652:KSE RS30565
gene id: 452652:KSE_RS30565
uniprot id: E4N1B2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

452652:KSE RS15830
gene id: 452652:KSE_RS15830
uniprot id: E4NCT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

452652:KSE RS33395
gene id: 452652:KSE_RS33395
uniprot id: E4N2X9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

452652:KSE RS04025
gene id: 452652:KSE_RS04025
uniprot id: E4N644
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

452652:KSE RS25515
gene id: 452652:KSE_RS25515
uniprot id: E4NHG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

452652:KSE RS21860
gene id: 452652:KSE_RS21860
uniprot id: E4NFD7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

452652:KSE RS24100
gene id: 452652:KSE_RS24100
uniprot id: E4NGN4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

452652:KSE RS16790
gene id: 452652:KSE_RS16790
uniprot id: E4NDC7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

452652:KSE RS33150
gene id: 452652:KSE_RS33150
uniprot id: E4N2T0
names: Subcellular Location Annotation
messages: Secreted

452652:KSE RS05100
gene id: 452652:KSE_RS05100
uniprot id: E4N6Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiX/PAD1 family. YclB subfamily.
messages: Homododecamer.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase.

452652:KSE RS17055
gene id: 452652:KSE_RS17055
uniprot id: E4NDH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

452652:KSE RS29610
gene id: 452652:KSE_RS29610
uniprot id: E4N0R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

452652:KSE RS27270
gene id: 452652:KSE_RS27270
uniprot id: E4NIF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS17750
gene id: 452652:KSE_RS17750
uniprot id: E4NDX1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS07495
gene id: 452652:KSE_RS07495
uniprot id: E4N832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

452652:KSE RS24505
gene id: 452652:KSE_RS24505
uniprot id: E4NGW5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

452652:KSE RS13855
gene id: 452652:KSE_RS13855
uniprot id: E4NBP4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

452652:KSE RS15545
gene id: 452652:KSE_RS15545
uniprot id: E4NCM9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

452652:KSE RS27415
gene id: 452652:KSE_RS27415
uniprot id: E4NII5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

452652:KSE RS02065
gene id: 452652:KSE_RS02065
uniprot id: E4N4Z6
names: Similarity
messages: Belongs to the FPG family.

452652:KSE RS33890
gene id: 452652:KSE_RS33890
uniprot id: E4N379
names: Similarity
messages: Belongs to the CsoR family.

452652:KSE RS11780
gene id: 452652:KSE_RS11780
uniprot id: E4NAI8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

452652:KSE RS15965
gene id: 452652:KSE_RS15965
uniprot id: E4NCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

452652:KSE RS10100
gene id: 452652:KSE_RS10100
uniprot id: E4N9J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

452652:KSE RS31425
gene id: 452652:KSE_RS31425
uniprot id: E4N1T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

452652:KSE RS19950
gene id: 452652:KSE_RS19950
uniprot id: E4NEQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452652:KSE RS23645
gene id: 452652:KSE_RS23645
uniprot id: E4NGE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

452652:KSE RS36945
gene id: 452652:KSE_RS36945
uniprot id: E4NJS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

452652:KSE RS35600
gene id: 452652:KSE_RS35600
uniprot id: E4NJ06
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

452652:KSE RS06195
gene id: 452652:KSE_RS06195
uniprot id: E4N7C4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

452652:KSE RS22605
gene id: 452652:KSE_RS22605
uniprot id: E4NFT7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

452652:KSE RS12330
gene id: 452652:KSE_RS12330
uniprot id: E4NAU9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

452652:KSE RS06850
gene id: 452652:KSE_RS06850
uniprot id: E4N7R0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS35585
gene id: 452652:KSE_RS35585
uniprot id: E4NJ03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS34515
gene id: 452652:KSE_RS34515
uniprot id: E4NKC9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS12995
gene id: 452652:KSE_RS12995
uniprot id: E4NB77
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

452652:KSE RS07855
gene id: 452652:KSE_RS07855
uniprot id: E4N8A2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

452652:KSE RS30210
gene id: 452652:KSE_RS30210
uniprot id: E4N138
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

452652:KSE RS35855
gene id: 452652:KSE_RS35855
uniprot id: E4NJ57
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

452652:KSE RS26440
gene id: 452652:KSE_RS26440
uniprot id: E4NHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

452652:KSE RS13005
gene id: 452652:KSE_RS13005
uniprot id: E4NB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

452652:KSE RS13755
gene id: 452652:KSE_RS13755
uniprot id: E4NBM4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

452652:KSE RS12640
gene id: 452652:KSE_RS12640
uniprot id: E4NB11
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

452652:KSE RS17850
gene id: 452652:KSE_RS17850
uniprot id: E4NDZ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS31680
gene id: 452652:KSE_RS31680
uniprot id: E4N1Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

452652:KSE RS28555
gene id: 452652:KSE_RS28555
uniprot id: E4N3R1
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

452652:KSE RS15100
gene id: 452652:KSE_RS15100
uniprot id: E4NCD9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

452652:KSE RS24935
gene id: 452652:KSE_RS24935
uniprot id: E4NH50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

452652:KSE RS10055
gene id: 452652:KSE_RS10055
uniprot id: E4N9I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

452652:KSE RS36710
gene id: 452652:KSE_RS36710
uniprot id: E4NJM9
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

452652:KSE RS32865
gene id: 452652:KSE_RS32865
uniprot id: E4N2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS08375
gene id: 452652:KSE_RS08375
uniprot id: E4N8K1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

452652:KSE RS29040
gene id: 452652:KSE_RS29040
uniprot id: E4N0F4
names: Similarity
messages: Belongs to the peptidase M1 family.

452652:KSE RS16405
gene id: 452652:KSE_RS16405
uniprot id: E4ND49
names: Similarity
messages: Belongs to the UbiD family.

452652:KSE RS20815
gene id: 452652:KSE_RS20815
uniprot id: E4MZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

452652:KSE RS26980
gene id: 452652:KSE_RS26980
uniprot id: E4NI98
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS40315
gene id: 452652:KSE_RS40315
uniprot id: E4NHF5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

452652:KSE RS04690
gene id: 452652:KSE_RS04690
uniprot id: E4N6H3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

452652:KSE RS18930
gene id: 452652:KSE_RS18930
uniprot id: E4MZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

452652:KSE RS23590
gene id: 452652:KSE_RS23590
uniprot id: E4NGD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

452652:KSE RS24555
gene id: 452652:KSE_RS24555
uniprot id: E4NGX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS08905
gene id: 452652:KSE_RS08905
uniprot id: E4N8V5
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS29435
gene id: 452652:KSE_RS29435
uniprot id: E4N0N2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS22885
gene id: 452652:KSE_RS22885
uniprot id: E4NFZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

452652:KSE RS07270
gene id: 452652:KSE_RS07270
uniprot id: E4N7Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

452652:KSE RS38545
gene id: 452652:KSE_RS38545
uniprot id: E4NDK5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

452652:KSE RS14030
gene id: 452652:KSE_RS14030
uniprot id: E4NBS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

452652:KSE RS22020
gene id: 452652:KSE_RS22020
uniprot id: E4NFH1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS06330
gene id: 452652:KSE_RS06330
uniprot id: E4N7F3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

452652:KSE RS07220
gene id: 452652:KSE_RS07220
uniprot id: E4N7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS25110
gene id: 452652:KSE_RS25110
uniprot id: E4NH85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS17345
gene id: 452652:KSE_RS17345
uniprot id: E4NDN9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15795
gene id: 452652:KSE_RS15795
uniprot id: E4NCS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

452652:KSE RS12780
gene id: 452652:KSE_RS12780
uniprot id: E4NB35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

452652:KSE RS15615
gene id: 452652:KSE_RS15615
uniprot id: E4NCP3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

452652:KSE RS13900
gene id: 452652:KSE_RS13900
uniprot id: E4NBQ2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS28105
gene id: 452652:KSE_RS28105
uniprot id: E4N0C7
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

452652:KSE RS11585
gene id: 452652:KSE_RS11585
uniprot id: E4NAE7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS27605
gene id: 452652:KSE_RS27605
uniprot id: E4N025
names: Similarity
messages: Belongs to the peptidase M1 family.

452652:KSE RS27225
gene id: 452652:KSE_RS27225
uniprot id: E4NIE7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS18130
gene id: 452652:KSE_RS18130
uniprot id: E4NE47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS04575
gene id: 452652:KSE_RS04575
uniprot id: E4N6F0
names: Similarity
messages: Belongs to the YciI family.

452652:KSE RS08255
gene id: 452652:KSE_RS08255
uniprot id: E4N8I0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

452652:KSE RS32170
gene id: 452652:KSE_RS32170
uniprot id: E4N284
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

452652:KSE RS09440
gene id: 452652:KSE_RS09440
uniprot id: E4N965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

452652:KSE RS06855
gene id: 452652:KSE_RS06855
uniprot id: E4N7R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

452652:KSE RS29535
gene id: 452652:KSE_RS29535
uniprot id: E4N0Q2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS25635
gene id: 452652:KSE_RS25635
uniprot id: E4NHI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

452652:KSE RS14195
gene id: 452652:KSE_RS14195
uniprot id: E4NBW0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

452652:KSE RS26245
gene id: 452652:KSE_RS26245
uniprot id: E4NHV7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

452652:KSE RS26215
gene id: 452652:KSE_RS26215
uniprot id: E4NHV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

452652:KSE RS26870
gene id: 452652:KSE_RS26870
uniprot id: E4NI79
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS03250
gene id: 452652:KSE_RS03250
uniprot id: E4N5N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS07410
gene id: 452652:KSE_RS07410
uniprot id: E4N815
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

452652:KSE RS15435
gene id: 452652:KSE_RS15435
uniprot id: E4NCK7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

452652:KSE RS11940
gene id: 452652:KSE_RS11940
uniprot id: E4NAM3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS10425
gene id: 452652:KSE_RS10425
uniprot id: E4N9R1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

452652:KSE RS03175
gene id: 452652:KSE_RS03175
uniprot id: E4N5M3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

452652:KSE RS27680
gene id: 452652:KSE_RS27680
uniprot id: E4N040
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS12580
gene id: 452652:KSE_RS12580
uniprot id: E4NAZ9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

452652:KSE RS34080
gene id: 452652:KSE_RS34080
uniprot id: E4N3B7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

452652:KSE RS13625
gene id: 452652:KSE_RS13625
uniprot id: E4NBK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

452652:KSE RS01935
gene id: 452652:KSE_RS01935
uniprot id: E4N4W9
names: Similarity
messages: Belongs to the CapA family.

452652:KSE RS12585
gene id: 452652:KSE_RS12585
uniprot id: E4NB00
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

452652:KSE RS21665
gene id: 452652:KSE_RS21665
uniprot id: E4NF97
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

452652:KSE RS38210
gene id: 452652:KSE_RS38210
uniprot id: E4N8D3
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.

452652:KSE RS06750
gene id: 452652:KSE_RS06750
uniprot id: E4N7P0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS15055
gene id: 452652:KSE_RS15055
uniprot id: E4NCD0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

452652:KSE RS35655
gene id: 452652:KSE_RS35655
uniprot id: E4NJ17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

452652:KSE RS35040
gene id: 452652:KSE_RS35040
uniprot id: E4NIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS36525
gene id: 452652:KSE_RS36525
uniprot id: E4NJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS34405
gene id: 452652:KSE_RS34405
uniprot id: E4N3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

452652:KSE RS18100
gene id: 452652:KSE_RS18100
uniprot id: E4NE41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

452652:KSE RS09280
gene id: 452652:KSE_RS09280
uniprot id: E4N933
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452652:KSE RS24815
gene id: 452652:KSE_RS24815
uniprot id: E4NH26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

452652:KSE RS01040
gene id: 452652:KSE_RS01040
uniprot id: E4N4D5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS11960
gene id: 452652:KSE_RS11960
uniprot id: E4NAM7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS14120
gene id: 452652:KSE_RS14120
uniprot id: E4NBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS10435
gene id: 452652:KSE_RS10435
uniprot id: E4N9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

452652:KSE RS11325
gene id: 452652:KSE_RS11325
uniprot id: E4NA95
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS03275
gene id: 452652:KSE_RS03275
uniprot id: E4N5P3
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

452652:KSE RS35030
gene id: 452652:KSE_RS35030
uniprot id: E4NIP2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

452652:KSE RS17070
gene id: 452652:KSE_RS17070
uniprot id: E4NDI2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS17015
gene id: 452652:KSE_RS17015
uniprot id: E4NDH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

452652:KSE RS19325
gene id: 452652:KSE_RS19325
uniprot id: E4MZD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

452652:KSE RS42870
gene id: 452652:KSE_RS42870
uniprot id: E4NEA9
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS14565
gene id: 452652:KSE_RS14565
uniprot id: E4NC32
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS25340
gene id: 452652:KSE_RS25340
uniprot id: E4NHC7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

452652:KSE RS10150
gene id: 452652:KSE_RS10150
uniprot id: E4N9K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

452652:KSE RS03700
gene id: 452652:KSE_RS03700
uniprot id: E4N5X9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

452652:KSE RS10250
gene id: 452652:KSE_RS10250
uniprot id: E4N9M7
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS18720
gene id: 452652:KSE_RS18720
uniprot id: E4NEG1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

452652:KSE RS05635
gene id: 452652:KSE_RS05635
uniprot id: E4N711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

452652:KSE RS26515
gene id: 452652:KSE_RS26515
uniprot id: E4NI08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS23825
gene id: 452652:KSE_RS23825
uniprot id: E4NGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS18065
gene id: 452652:KSE_RS18065
uniprot id: E4NE34
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS06915
gene id: 452652:KSE_RS06915
uniprot id: E4N7S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

452652:KSE RS16125
gene id: 452652:KSE_RS16125
uniprot id: E4NCZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS13215
gene id: 452652:KSE_RS13215
uniprot id: E4NBB8
names: Similarity
messages: Belongs to the universal stress protein A family.

452652:KSE RS15480
gene id: 452652:KSE_RS15480
uniprot id: E4NCL6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

452652:KSE RS17760
gene id: 452652:KSE_RS17760
uniprot id: E4NDX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

452652:KSE RS15045
gene id: 452652:KSE_RS15045
uniprot id: E4NCC8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS34885
gene id: 452652:KSE_RS34885
uniprot id: E4NIL3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS31360
gene id: 452652:KSE_RS31360
uniprot id: E4N1R9
names: Subunit
messages: Homotetramer.

452652:KSE RS04760
gene id: 452652:KSE_RS04760
uniprot id: E4N6I7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

452652:KSE RS07445
gene id: 452652:KSE_RS07445
uniprot id: E4N822
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

452652:KSE RS13365
gene id: 452652:KSE_RS13365
uniprot id: E4NBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

452652:KSE RS34120
gene id: 452652:KSE_RS34120
uniprot id: E4N3C5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

452652:KSE RS15610
gene id: 452652:KSE_RS15610
uniprot id: E4NCP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

452652:KSE RS24670
gene id: 452652:KSE_RS24670
uniprot id: E4NGZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

452652:KSE RS10600
gene id: 452652:KSE_RS10600
uniprot id: E4N9U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

452652:KSE RS02730
gene id: 452652:KSE_RS02730
uniprot id: E4N5D3
names: Subunit
messages: Homodimer.

452652:KSE RS15475
gene id: 452652:KSE_RS15475
uniprot id: E4NCL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

452652:KSE RS15465
gene id: 452652:KSE_RS15465
uniprot id: E4NCL3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

452652:KSE RS18095
gene id: 452652:KSE_RS18095
uniprot id: E4NE40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

452652:KSE RS09410
gene id: 452652:KSE_RS09410
uniprot id: E4N959
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

452652:KSE RS30380
gene id: 452652:KSE_RS30380
uniprot id: E4N173
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS15640
gene id: 452652:KSE_RS15640
uniprot id: E4NCP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

452652:KSE RS01540
gene id: 452652:KSE_RS01540
uniprot id: E4N4N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

452652:KSE RS07535
gene id: 452652:KSE_RS07535
uniprot id: E4N837
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

452652:KSE RS16110
gene id: 452652:KSE_RS16110
uniprot id: E4NCY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS09260
gene id: 452652:KSE_RS09260
uniprot id: E4N929
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

452652:KSE RS15790
gene id: 452652:KSE_RS15790
uniprot id: E4NCS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

452652:KSE RS15095
gene id: 452652:KSE_RS15095
uniprot id: E4NCD8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS01830
gene id: 452652:KSE_RS01830
uniprot id: E4N4U7
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

452652:KSE RS16880
gene id: 452652:KSE_RS16880
uniprot id: E4NDE5
names: Similarity
messages: Belongs to the Nth/MutY family.

452652:KSE RS20805
gene id: 452652:KSE_RS20805
uniprot id: E4MZS2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS16885
gene id: 452652:KSE_RS16885
uniprot id: E4NDE6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS21410
gene id: 452652:KSE_RS21410
uniprot id: E4NF45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

452652:KSE RS26925
gene id: 452652:KSE_RS26925
uniprot id: E4NI87
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS25965
gene id: 452652:KSE_RS25965
uniprot id: E4NHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

452652:KSE RS41600
gene id: 452652:KSE_RS41600
uniprot id: E4N1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

452652:KSE RS16455
gene id: 452652:KSE_RS16455
uniprot id: E4ND59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS15325
gene id: 452652:KSE_RS15325
uniprot id: E4NCI6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

452652:KSE RS19720
gene id: 452652:KSE_RS19720
uniprot id: E4NEK3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS21325
gene id: 452652:KSE_RS21325
uniprot id: E4NF30
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS29755
gene id: 452652:KSE_RS29755
uniprot id: E4N0U7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS13145
gene id: 452652:KSE_RS13145
uniprot id: E4NBA4
names: Similarity
messages: Belongs to the peptidase S66 family.

452652:KSE RS09780
gene id: 452652:KSE_RS09780
uniprot id: E4N9D3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

452652:KSE RS21685
gene id: 452652:KSE_RS21685
uniprot id: E4NFA1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

452652:KSE RS22655
gene id: 452652:KSE_RS22655
uniprot id: E4NFU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

452652:KSE RS25450
gene id: 452652:KSE_RS25450
uniprot id: E4NHE9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

452652:KSE RS00705
gene id: 452652:KSE_RS00705
uniprot id: E4N467
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452652:KSE RS22140
gene id: 452652:KSE_RS22140
uniprot id: E4NFJ6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS30780
gene id: 452652:KSE_RS30780
uniprot id: E4N1F4
names: Similarity
messages: Belongs to the UPF0145 family.

452652:KSE RS33745
gene id: 452652:KSE_RS33745
uniprot id: E4N350
names: Similarity
messages: Belongs to the OsmC/Ohr family.

452652:KSE RS34505
gene id: 452652:KSE_RS34505
uniprot id: E4NKC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

452652:KSE RS31370
gene id: 452652:KSE_RS31370
uniprot id: E4N1S1
names: Similarity
messages: Belongs to the catalase family.

452652:KSE RS00775
gene id: 452652:KSE_RS00775
uniprot id: E4N480
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

452652:KSE RS12980
gene id: 452652:KSE_RS12980
uniprot id: E4NB74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

452652:KSE RS06590
gene id: 452652:KSE_RS06590
uniprot id: E4N7K8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

452652:KSE RS22155
gene id: 452652:KSE_RS22155
uniprot id: E4NFJ9
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS13410
gene id: 452652:KSE_RS13410
uniprot id: E4NBF6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS07405
gene id: 452652:KSE_RS07405
uniprot id: E4N814
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

452652:KSE RS22645
gene id: 452652:KSE_RS22645
uniprot id: E4NFU4
names: Similarity
messages: Belongs to the YjdM family.

452652:KSE RS04940
gene id: 452652:KSE_RS04940
uniprot id: E4N6M2
names: Similarity
messages: Belongs to the DapA family.

452652:KSE RS19345
gene id: 452652:KSE_RS19345
uniprot id: E4MZE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

452652:KSE RS17370
gene id: 452652:KSE_RS17370
uniprot id: E4NDP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS30700
gene id: 452652:KSE_RS30700
uniprot id: E4N1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

452652:KSE RS10415
gene id: 452652:KSE_RS10415
uniprot id: E4N9Q9
names: Similarity
messages: Belongs to the YggT family.

452652:KSE RS19145
gene id: 452652:KSE_RS19145
uniprot id: E4MZA2
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

452652:KSE RS10290
gene id: 452652:KSE_RS10290
uniprot id: E4N9N5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS29805
gene id: 452652:KSE_RS29805
uniprot id: E4N0V8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

452652:KSE RS35770
gene id: 452652:KSE_RS35770
uniprot id: E4NJ40
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS10195
gene id: 452652:KSE_RS10195
uniprot id: E4N9L6
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

452652:KSE RS18200
gene id: 452652:KSE_RS18200
uniprot id: E4NE61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS20170
gene id: 452652:KSE_RS20170
uniprot id: E4NEU5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

452652:KSE RS26340
gene id: 452652:KSE_RS26340
uniprot id: E4NHX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

452652:KSE RS17295
gene id: 452652:KSE_RS17295
uniprot id: E4NDM8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS24685
gene id: 452652:KSE_RS24685
uniprot id: E4NH00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

452652:KSE RS36520
gene id: 452652:KSE_RS36520
uniprot id: E4NJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS35620
gene id: 452652:KSE_RS35620
uniprot id: E4NJ10
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15690
gene id: 452652:KSE_RS15690
uniprot id: E4NCQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

452652:KSE RS12465
gene id: 452652:KSE_RS12465
uniprot id: E4NAX5
names: Similarity
messages: Belongs to the Fur family.

452652:KSE RS22160
gene id: 452652:KSE_RS22160
uniprot id: E4NFK0
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

452652:KSE RS12255
gene id: 452652:KSE_RS12255
uniprot id: E4NAT7
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

452652:KSE RS24765
gene id: 452652:KSE_RS24765
uniprot id: E4NH16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

452652:KSE RS29255
gene id: 452652:KSE_RS29255
uniprot id: E4N0J6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

452652:KSE RS16275
gene id: 452652:KSE_RS16275
uniprot id: E4ND23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS13620
gene id: 452652:KSE_RS13620
uniprot id: E4NBJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS12955
gene id: 452652:KSE_RS12955
uniprot id: E4NB69
names: Similarity
messages: Belongs to the peptidase M1 family.

452652:KSE RS24540
gene id: 452652:KSE_RS24540
uniprot id: E4NGX2
names: Similarity
messages: Belongs to the peptidase C40 family.

452652:KSE RS22575
gene id: 452652:KSE_RS22575
uniprot id: E4NFT1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS12570
gene id: 452652:KSE_RS12570
uniprot id: E4NAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

452652:KSE RS27250
gene id: 452652:KSE_RS27250
uniprot id: E4NIF2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452652:KSE RS15820
gene id: 452652:KSE_RS15820
uniprot id: E4NCT4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

452652:KSE RS25590
gene id: 452652:KSE_RS25590
uniprot id: E4NHH9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

452652:KSE RS10745
gene id: 452652:KSE_RS10745
uniprot id: E4N9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

452652:KSE RS35075
gene id: 452652:KSE_RS35075
uniprot id: E4NIQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS13630
gene id: 452652:KSE_RS13630
uniprot id: E4NBK1
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

452652:KSE RS01845
gene id: 452652:KSE_RS01845
uniprot id: E4N4V0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

452652:KSE RS34960
gene id: 452652:KSE_RS34960
uniprot id: E4NIM8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS13200
gene id: 452652:KSE_RS13200
uniprot id: E4NBB5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS30250
gene id: 452652:KSE_RS30250
uniprot id: E4N146
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

452652:KSE RS36750
gene id: 452652:KSE_RS36750
uniprot id: E4NJN7
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS08020
gene id: 452652:KSE_RS08020
uniprot id: E4N8D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452652:KSE RS10465
gene id: 452652:KSE_RS10465
uniprot id: E4N9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

452652:KSE RS00425
gene id: 452652:KSE_RS00425
uniprot id: E4N408
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

452652:KSE RS05220
gene id: 452652:KSE_RS05220
uniprot id: E4N6S8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS08105
gene id: 452652:KSE_RS08105
uniprot id: E4N8E9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS31645
gene id: 452652:KSE_RS31645
uniprot id: E4N1X7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS20615
gene id: 452652:KSE_RS20615
uniprot id: E4MZN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

452652:KSE RS33295
gene id: 452652:KSE_RS33295
uniprot id: E4N2V9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

452652:KSE RS36990
gene id: 452652:KSE_RS36990
uniprot id: E4NJT5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

452652:KSE RS32885
gene id: 452652:KSE_RS32885
uniprot id: E4N2M6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

452652:KSE RS04145
gene id: 452652:KSE_RS04145
uniprot id: E4N667
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

452652:KSE RS25505
gene id: 452652:KSE_RS25505
uniprot id: E4NHG1
names: Subunit
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

452652:KSE RS32045
gene id: 452652:KSE_RS32045
uniprot id: E4N259
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

452652:KSE RS20835
gene id: 452652:KSE_RS20835
uniprot id: E4MZS8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

452652:KSE RS20425
gene id: 452652:KSE_RS20425
uniprot id: E4MZK0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS31625
gene id: 452652:KSE_RS31625
uniprot id: E4N1X3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

452652:KSE RS29155
gene id: 452652:KSE_RS29155
uniprot id: E4N0H7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS14285
gene id: 452652:KSE_RS14285
uniprot id: E4NBX8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS00105
gene id: 452652:KSE_RS00105
uniprot id: E4MYY0
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the terpene synthase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (2Z,6E)-hedycaryol via a 1,11-cyclization.
messages: Homodimer.
messages: The 1,11-cyclization requires isomerization of (2E,6E)-farnesyl diphosphate (FPP) to nerolidyl diphosphate (NPP), the abstraction of the pyrophosphate from intermediate NPP leading to a (Z,E)-hedycaryl cation and finally an nucleophilic attack of a water molecule.
messages: The Asp-Asp-Xaa-Xaa-Xaa-Glu (DDXXXE) and Asn-Xaa-Xaa-Xaa-Ser-Xaa-Xaa-Xaa-Glu (NSE) motifs are important for the catalytic activity, presumably through binding to Mg(2+).

452652:KSE RS03185
gene id: 452652:KSE_RS03185
uniprot id: E4N5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

452652:KSE RS32620
gene id: 452652:KSE_RS32620
uniprot id: E4N2H3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS12735
gene id: 452652:KSE_RS12735
uniprot id: E4NB25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

452652:KSE RS30875
gene id: 452652:KSE_RS30875
uniprot id: E4N1H2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

452652:KSE RS05190
gene id: 452652:KSE_RS05190
uniprot id: E4N6S1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

452652:KSE RS22710
gene id: 452652:KSE_RS22710
uniprot id: E4NFV9
names: Similarity
messages: Belongs to the terpene synthase family.

452652:KSE RS06705
gene id: 452652:KSE_RS06705
uniprot id: E4N7N1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS14470
gene id: 452652:KSE_RS14470
uniprot id: E4NC13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

452652:KSE RS02110
gene id: 452652:KSE_RS02110
uniprot id: E4N505
names: Similarity
messages: Belongs to the pirin family.

452652:KSE RS18440
gene id: 452652:KSE_RS18440
uniprot id: E4NEB0
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS31080
gene id: 452652:KSE_RS31080
uniprot id: E4N1L2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

452652:KSE RS12795
gene id: 452652:KSE_RS12795
uniprot id: E4NB38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

452652:KSE RS26780
gene id: 452652:KSE_RS26780
uniprot id: E4NI61
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

452652:KSE RS04200
gene id: 452652:KSE_RS04200
uniprot id: E4N678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

452652:KSE RS15405
gene id: 452652:KSE_RS15405
uniprot id: E4NCK1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

452652:KSE RS24710
gene id: 452652:KSE_RS24710
uniprot id: E4NH05
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

452652:KSE RS21295
gene id: 452652:KSE_RS21295
uniprot id: E4NF24
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS19315
gene id: 452652:KSE_RS19315
uniprot id: E4MZD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

452652:KSE RS10750
gene id: 452652:KSE_RS10750
uniprot id: E4N9X7
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

452652:KSE RS32930
gene id: 452652:KSE_RS32930
uniprot id: E4N2N5
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

452652:KSE RS15220
gene id: 452652:KSE_RS15220
uniprot id: E4NCG4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

452652:KSE RS00445
gene id: 452652:KSE_RS00445
uniprot id: E4N412
names: Similarity
messages: Belongs to the TPP enzyme family.

452652:KSE RS31620
gene id: 452652:KSE_RS31620
uniprot id: E4N1X2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS31870
gene id: 452652:KSE_RS31870
uniprot id: E4N224
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452652:KSE RS10015
gene id: 452652:KSE_RS10015
uniprot id: E4N9H9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

452652:KSE RS17450
gene id: 452652:KSE_RS17450
uniprot id: E4NDR0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452652:KSE RS23555
gene id: 452652:KSE_RS23555
uniprot id: E4NGC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS00650
gene id: 452652:KSE_RS00650
uniprot id: E4N456
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS36045
gene id: 452652:KSE_RS36045
uniprot id: E4NJ96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS18970
gene id: 452652:KSE_RS18970
uniprot id: E4MZ69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

452652:KSE RS15705
gene id: 452652:KSE_RS15705
uniprot id: E4NCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

452652:KSE RS14760
gene id: 452652:KSE_RS14760
uniprot id: E4NC73
names: Similarity
messages: Belongs to the phosphohexose mutase family.

452652:KSE RS07340
gene id: 452652:KSE_RS07340
uniprot id: E4N801
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS06290
gene id: 452652:KSE_RS06290
uniprot id: E4N7E5
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the terpene synthase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (+)-corvol ether A and (+)-corvol ether B via a 1,10-cyclization, which requires isomerization of FPP to nerolidyl diphosphate (NPP) and then abstraction of the pyrophosphate from intermediate NPP leading to a (E,Z)-germacradienyl (helminthogermacradienyl) cation (PubMed:25809275, PubMed:27666571). The preferred substrate is (2E,6E)-farnesyl diphosphate (FPP), however geranyl diphosphate (GPP) is also able to produce small amounts of several acyclic and cyclic monoterpenes, with linalool as the main product (PubMed:25809275).
messages: The Asp-Asp-Xaa-Xaa-Xaa-Asp (DDXXXD) motif is important for the catalytic activity, presumably through binding to Mg(2+).

452652:KSE RS17880
gene id: 452652:KSE_RS17880
uniprot id: E4NDZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

452652:KSE RS16020
gene id: 452652:KSE_RS16020
uniprot id: E4NCX1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452652:KSE RS15710
gene id: 452652:KSE_RS15710
uniprot id: E4NCR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

452652:KSE RS24665
gene id: 452652:KSE_RS24665
uniprot id: E4NGZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

452652:KSE RS15500
gene id: 452652:KSE_RS15500
uniprot id: E4NCM0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452652:KSE RS31130
gene id: 452652:KSE_RS31130
uniprot id: E4N1M2
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

452652:KSE RS08140
gene id: 452652:KSE_RS08140
uniprot id: E4N8F6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS10680
gene id: 452652:KSE_RS10680
uniprot id: E4N9W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

452652:KSE RS24770
gene id: 452652:KSE_RS24770
uniprot id: E4NH17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

452652:KSE RS07425
gene id: 452652:KSE_RS07425
uniprot id: E4N818
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

452652:KSE RS20020
gene id: 452652:KSE_RS20020
uniprot id: E4NER6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

452652:KSE RS01825
gene id: 452652:KSE_RS01825
uniprot id: E4N4U6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS08135
gene id: 452652:KSE_RS08135
uniprot id: E4N8F5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS26575
gene id: 452652:KSE_RS26575
uniprot id: E4NI20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS01840
gene id: 452652:KSE_RS01840
uniprot id: E4N4U9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

452652:KSE RS07265
gene id: 452652:KSE_RS07265
uniprot id: E4N7Y6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

452652:KSE RS12940
gene id: 452652:KSE_RS12940
uniprot id: E4NB66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

452652:KSE RS07345
gene id: 452652:KSE_RS07345
uniprot id: E4N802
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

452652:KSE RS16665
gene id: 452652:KSE_RS16665
uniprot id: E4NDA2
names: Similarity
messages: Belongs to the histone deacetylase family.

452652:KSE RS24700
gene id: 452652:KSE_RS24700
uniprot id: E4NH03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

452652:KSE RS07430
gene id: 452652:KSE_RS07430
uniprot id: E4N819
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

452652:KSE RS15330
gene id: 452652:KSE_RS15330
uniprot id: E4NCI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS17915
gene id: 452652:KSE_RS17915
uniprot id: E4NE04
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS35055
gene id: 452652:KSE_RS35055
uniprot id: E4NIP7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS12615
gene id: 452652:KSE_RS12615
uniprot id: E4NB06
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS26000
gene id: 452652:KSE_RS26000
uniprot id: E4NHR1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS32590
gene id: 452652:KSE_RS32590
uniprot id: E4N2G7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS27775
gene id: 452652:KSE_RS27775
uniprot id: E4N059
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

452652:KSE RS36080
gene id: 452652:KSE_RS36080
uniprot id: E4NJA3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS08730
gene id: 452652:KSE_RS08730
uniprot id: E4N8S1
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

452652:KSE RS13615
gene id: 452652:KSE_RS13615
uniprot id: E4NBJ8
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

452652:KSE RS34370
gene id: 452652:KSE_RS34370
uniprot id: E4N3H5
names: Similarity
messages: Belongs to the LOR family.

452652:KSE RS32420
gene id: 452652:KSE_RS32420
uniprot id: E4N2D3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09335
gene id: 452652:KSE_RS09335
uniprot id: E4N944
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS31350
gene id: 452652:KSE_RS31350
uniprot id: E4N1R7
names: Similarity
messages: Belongs to the HIBADH-related family.

452652:KSE RS32935
gene id: 452652:KSE_RS32935
uniprot id: E4N2N6
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

452652:KSE RS06740
gene id: 452652:KSE_RS06740
uniprot id: E4N7N8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

452652:KSE RS28500
gene id: 452652:KSE_RS28500
uniprot id: E4N3Q0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

452652:KSE RS34135
gene id: 452652:KSE_RS34135
uniprot id: E4N3C8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

452652:KSE RS27460
gene id: 452652:KSE_RS27460
uniprot id: E4MZZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

452652:KSE RS06610
gene id: 452652:KSE_RS06610
uniprot id: E4N7L2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS25630
gene id: 452652:KSE_RS25630
uniprot id: E4NHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

452652:KSE RS11395
gene id: 452652:KSE_RS11395
uniprot id: E4NAA9
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

452652:KSE RS22800
gene id: 452652:KSE_RS22800
uniprot id: E4NFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

452652:KSE RS26235
gene id: 452652:KSE_RS26235
uniprot id: E4NHV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

452652:KSE RS05265
gene id: 452652:KSE_RS05265
uniprot id: E4N6T7
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

452652:KSE RS26495
gene id: 452652:KSE_RS26495
uniprot id: E4NI04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

452652:KSE RS24305
gene id: 452652:KSE_RS24305
uniprot id: E4NGS5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

452652:KSE RS13515
gene id: 452652:KSE_RS13515
uniprot id: E4NBH8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS14215
gene id: 452652:KSE_RS14215
uniprot id: E4NBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

452652:KSE RS22975
gene id: 452652:KSE_RS22975
uniprot id: E4NG09
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

452652:KSE RS20970
gene id: 452652:KSE_RS20970
uniprot id: E4MZV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS22115
gene id: 452652:KSE_RS22115
uniprot id: E4NFJ1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS00310
gene id: 452652:KSE_RS00310
uniprot id: E4MZ23
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

452652:KSE RS37475
gene id: 452652:KSE_RS37475
uniprot id: E4N415
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

452652:KSE RS01550
gene id: 452652:KSE_RS01550
uniprot id: E4N4P0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS19765
gene id: 452652:KSE_RS19765
uniprot id: E4NEL3
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

452652:KSE RS35435
gene id: 452652:KSE_RS35435
uniprot id: E4NIX4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

452652:KSE RS11595
gene id: 452652:KSE_RS11595
uniprot id: E4NAE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

452652:KSE RS11300
gene id: 452652:KSE_RS11300
uniprot id: E4NA90
names: Similarity
messages: Belongs to the group II decarboxylase family.

452652:KSE RS04380
gene id: 452652:KSE_RS04380
uniprot id: E4N6B4
names: Similarity
messages: Belongs to the group II decarboxylase family.

452652:KSE RS19410
gene id: 452652:KSE_RS19410
uniprot id: E4MZF4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

452652:KSE RS28300
gene id: 452652:KSE_RS28300
uniprot id: E4N3L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS11465
gene id: 452652:KSE_RS11465
uniprot id: E4NAC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

452652:KSE RS12745
gene id: 452652:KSE_RS12745
uniprot id: E4NB27
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

452652:KSE RS06410
gene id: 452652:KSE_RS06410
uniprot id: E4N7H1
names: Similarity
messages: Belongs to the CTP synthase family.

452652:KSE RS32460
gene id: 452652:KSE_RS32460
uniprot id: E4N2E1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS26635
gene id: 452652:KSE_RS26635
uniprot id: E4NI32
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

452652:KSE RS34095
gene id: 452652:KSE_RS34095
uniprot id: E4N3C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

452652:KSE RS33680
gene id: 452652:KSE_RS33680
uniprot id: E4N337
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS31875
gene id: 452652:KSE_RS31875
uniprot id: E4N225
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS16335
gene id: 452652:KSE_RS16335
uniprot id: E4ND35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

452652:KSE RS27130
gene id: 452652:KSE_RS27130
uniprot id: E4NIC8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS10235
gene id: 452652:KSE_RS10235
uniprot id: E4N9M4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS18625
gene id: 452652:KSE_RS18625
uniprot id: E4NEE2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS09640
gene id: 452652:KSE_RS09640
uniprot id: E4N9A6
names: Similarity
messages: Belongs to the agmatine deiminase family.

452652:KSE RS14965
gene id: 452652:KSE_RS14965
uniprot id: E4NCB2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

452652:KSE RS27150
gene id: 452652:KSE_RS27150
uniprot id: E4NID2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

452652:KSE RS23580
gene id: 452652:KSE_RS23580
uniprot id: E4NGC8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

452652:KSE RS27280
gene id: 452652:KSE_RS27280
uniprot id: E4NIF8
names: Function
names: Similarity
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

452652:KSE RS37565
gene id: 452652:KSE_RS37565
uniprot id: E4MZ35
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

452652:KSE RS04080
gene id: 452652:KSE_RS04080
uniprot id: E4N655
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

452652:KSE RS36725
gene id: 452652:KSE_RS36725
uniprot id: E4NJN2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS00910
gene id: 452652:KSE_RS00910
uniprot id: E4N4A9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

452652:KSE RS11320
gene id: 452652:KSE_RS11320
uniprot id: E4NA94
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

452652:KSE RS25655
gene id: 452652:KSE_RS25655
uniprot id: E4NHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

452652:KSE RS22025
gene id: 452652:KSE_RS22025
uniprot id: E4NFH2
names: Similarity
messages: Belongs to the citrate synthase family.

452652:KSE RS34705
gene id: 452652:KSE_RS34705
uniprot id: E4MYU1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

452652:KSE RS12700
gene id: 452652:KSE_RS12700
uniprot id: E4NB22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS27520
gene id: 452652:KSE_RS27520
uniprot id: E4N008
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

452652:KSE RS04355
gene id: 452652:KSE_RS04355
uniprot id: E4N6A9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS36055
gene id: 452652:KSE_RS36055
uniprot id: E4NJ98
names: Similarity
messages: Belongs to the peptidase C40 family.

452652:KSE RS37660
gene id: 452652:KSE_RS37660
uniprot id: E4MZ16
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS30120
gene id: 452652:KSE_RS30120
uniprot id: E4N121
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

452652:KSE RS25365
gene id: 452652:KSE_RS25365
uniprot id: E4NHD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

452652:KSE RS12475
gene id: 452652:KSE_RS12475
uniprot id: E4NAX7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

452652:KSE RS10945
gene id: 452652:KSE_RS10945
uniprot id: E4NA16
names: Similarity
messages: Belongs to the CdaR family.

452652:KSE RS00720
gene id: 452652:KSE_RS00720
uniprot id: E4N470
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS19025
gene id: 452652:KSE_RS19025
uniprot id: E4MZ78
names: Similarity
messages: Belongs to the GARS family.

452652:KSE RS14670
gene id: 452652:KSE_RS14670
uniprot id: E4NC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

452652:KSE RS13915
gene id: 452652:KSE_RS13915
uniprot id: E4NBQ5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

452652:KSE RS08885
gene id: 452652:KSE_RS08885
uniprot id: E4N8V2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

452652:KSE RS10420
gene id: 452652:KSE_RS10420
uniprot id: E4N9R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

452652:KSE RS19380
gene id: 452652:KSE_RS19380
uniprot id: E4MZE9
names: Similarity
messages: Belongs to the CFA/CMAS family.

452652:KSE RS26700
gene id: 452652:KSE_RS26700
uniprot id: E4NI45
names: Similarity
messages: Belongs to the peptidase S33 family.

452652:KSE RS23060
gene id: 452652:KSE_RS23060
uniprot id: E4NG26
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

452652:KSE RS21795
gene id: 452652:KSE_RS21795
uniprot id: E4NFC3
names: Similarity
messages: Belongs to the CutC family.

452652:KSE RS33050
gene id: 452652:KSE_RS33050
uniprot id: E4N2R0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS37460
gene id: 452652:KSE_RS37460
uniprot id: E4N418
names: Similarity
messages: Belongs to the phosphohexose mutase family.

452652:KSE RS25005
gene id: 452652:KSE_RS25005
uniprot id: E4NH64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

452652:KSE RS30685
gene id: 452652:KSE_RS30685
uniprot id: E4N1D6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS31140
gene id: 452652:KSE_RS31140
uniprot id: E4N1M4
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS32500
gene id: 452652:KSE_RS32500
uniprot id: E4N2E9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09590
gene id: 452652:KSE_RS09590
uniprot id: E4N996
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

452652:KSE RS13495
gene id: 452652:KSE_RS13495
uniprot id: E4NBH3
names: Similarity
messages: Belongs to the PrpD family.

452652:KSE RS14895
gene id: 452652:KSE_RS14895
uniprot id: E4NCA0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09580
gene id: 452652:KSE_RS09580
uniprot id: E4N994
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS14920
gene id: 452652:KSE_RS14920
uniprot id: E4NCA4
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS24870
gene id: 452652:KSE_RS24870
uniprot id: E4NH37
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

452652:KSE RS28235
gene id: 452652:KSE_RS28235
uniprot id: E4N3K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

452652:KSE RS14640
gene id: 452652:KSE_RS14640
uniprot id: E4NC48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

452652:KSE RS36695
gene id: 452652:KSE_RS36695
uniprot id: E4NJM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

452652:KSE RS30165
gene id: 452652:KSE_RS30165
uniprot id: E4N130
names: Similarity
messages: Belongs to the CutA family.

452652:KSE RS07050
gene id: 452652:KSE_RS07050
uniprot id: E4N7V0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452652:KSE RS30590
gene id: 452652:KSE_RS30590
uniprot id: E4N1B7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS10650
gene id: 452652:KSE_RS10650
uniprot id: E4N9V7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS16860
gene id: 452652:KSE_RS16860
uniprot id: E4NDE1
names: Similarity
messages: Belongs to the threonine aldolase family.

452652:KSE RS06010
gene id: 452652:KSE_RS06010
uniprot id: E4N787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452652:KSE RS23785
gene id: 452652:KSE_RS23785
uniprot id: E4NGG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS17405
gene id: 452652:KSE_RS17405
uniprot id: E4NDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

452652:KSE RS16610
gene id: 452652:KSE_RS16610
uniprot id: E4ND91
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

452652:KSE RS00645
gene id: 452652:KSE_RS00645
uniprot id: E4N455
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

452652:KSE RS09345
gene id: 452652:KSE_RS09345
uniprot id: E4N946
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452652:KSE RS19420
gene id: 452652:KSE_RS19420
uniprot id: E4MZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

452652:KSE RS19185
gene id: 452652:KSE_RS19185
uniprot id: E4MZA9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09070
gene id: 452652:KSE_RS09070
uniprot id: E4N8Z1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

452652:KSE RS35805
gene id: 452652:KSE_RS35805
uniprot id: E4NJ47
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15805
gene id: 452652:KSE_RS15805
uniprot id: E4NCT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

452652:KSE RS19010
gene id: 452652:KSE_RS19010
uniprot id: E4MZ75
names: Similarity
messages: Belongs to the SAICAR synthetase family.

452652:KSE RS35665
gene id: 452652:KSE_RS35665
uniprot id: E4NJ19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS44705
gene id: 452652:KSE_RS44705
uniprot id: E4NCA9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS19770
gene id: 452652:KSE_RS19770
uniprot id: E4NEL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

452652:KSE RS03140
gene id: 452652:KSE_RS03140
uniprot id: E4N5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

452652:KSE RS15555
gene id: 452652:KSE_RS15555
uniprot id: E4NCN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

452652:KSE RS10430
gene id: 452652:KSE_RS10430
uniprot id: E4N9R2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

452652:KSE RS29615
gene id: 452652:KSE_RS29615
uniprot id: E4N0R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

452652:KSE RS27625
gene id: 452652:KSE_RS27625
uniprot id: E4N029
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

452652:KSE RS30410
gene id: 452652:KSE_RS30410
uniprot id: E4N181
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

452652:KSE RS26300
gene id: 452652:KSE_RS26300
uniprot id: E4NHW8
names: Similarity
messages: Belongs to the WXG100 family.

452652:KSE RS16260
gene id: 452652:KSE_RS16260
uniprot id: E4ND20
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09825
gene id: 452652:KSE_RS09825
uniprot id: E4N9E2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS30385
gene id: 452652:KSE_RS30385
uniprot id: E4N174
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS37830
gene id: 452652:KSE_RS37830
uniprot id: E4MYY0
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the terpene synthase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (2Z,6E)-hedycaryol via a 1,11-cyclization.
messages: Homodimer.
messages: The 1,11-cyclization requires isomerization of (2E,6E)-farnesyl diphosphate (FPP) to nerolidyl diphosphate (NPP), the abstraction of the pyrophosphate from intermediate NPP leading to a (Z,E)-hedycaryl cation and finally an nucleophilic attack of a water molecule.
messages: The Asp-Asp-Xaa-Xaa-Xaa-Glu (DDXXXE) and Asn-Xaa-Xaa-Xaa-Ser-Xaa-Xaa-Xaa-Glu (NSE) motifs are important for the catalytic activity, presumably through binding to Mg(2+).

452652:KSE RS26405
gene id: 452652:KSE_RS26405
uniprot id: E4NHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

452652:KSE RS35565
gene id: 452652:KSE_RS35565
uniprot id: E4NIZ9
names: Similarity
messages: Belongs to the peptidase M4 family.

452652:KSE RS05700
gene id: 452652:KSE_RS05700
uniprot id: E4N724
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS02495
gene id: 452652:KSE_RS02495
uniprot id: E4N587
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS22235
gene id: 452652:KSE_RS22235
uniprot id: E4NFL5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

452652:KSE RS15600
gene id: 452652:KSE_RS15600
uniprot id: E4NCP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

452652:KSE RS28390
gene id: 452652:KSE_RS28390
uniprot id: E4N3M8
names: Similarity
messages: Belongs to the TlyA family.

452652:KSE RS26185
gene id: 452652:KSE_RS26185
uniprot id: E4NHU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

452652:KSE RS06985
gene id: 452652:KSE_RS06985
uniprot id: E4N7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

452652:KSE RS10490
gene id: 452652:KSE_RS10490
uniprot id: E4N9S4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

452652:KSE RS10805
gene id: 452652:KSE_RS10805
uniprot id: E4N9Y8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Belongs to the sulfur carrier protein TusA family.

452652:KSE RS15845
gene id: 452652:KSE_RS15845
uniprot id: E4NCT8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

452652:KSE RS31895
gene id: 452652:KSE_RS31895
uniprot id: E4N229
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

452652:KSE RS21055
gene id: 452652:KSE_RS21055
uniprot id: E4MZX2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS25190
gene id: 452652:KSE_RS25190
uniprot id: E4NHA1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS26260
gene id: 452652:KSE_RS26260
uniprot id: E4NHW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS26665
gene id: 452652:KSE_RS26665
uniprot id: E4NI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS01185
gene id: 452652:KSE_RS01185
uniprot id: E4N4G4
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS05565
gene id: 452652:KSE_RS05565
uniprot id: E4N6Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

452652:KSE RS06680
gene id: 452652:KSE_RS06680
uniprot id: E4N7M6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

452652:KSE RS16465
gene id: 452652:KSE_RS16465
uniprot id: E4ND61
names: Similarity
messages: Belongs to the UPF0098 family.

452652:KSE RS10975
gene id: 452652:KSE_RS10975
uniprot id: E4NA23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

452652:KSE RS12225
gene id: 452652:KSE_RS12225
uniprot id: E4NAT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

452652:KSE RS16240
gene id: 452652:KSE_RS16240
uniprot id: E4ND16
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS25475
gene id: 452652:KSE_RS25475
uniprot id: E4NHF4
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

452652:KSE RS26600
gene id: 452652:KSE_RS26600
uniprot id: E4NI25
names: Similarity
messages: Belongs to the IucA/IucC family.

452652:KSE RS23640
gene id: 452652:KSE_RS23640
uniprot id: E4NGE0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS05280
gene id: 452652:KSE_RS05280
uniprot id: E4N6U0
names: Similarity
messages: Belongs to the peptidase S9A family.

452652:KSE RS23375
gene id: 452652:KSE_RS23375
uniprot id: E4NG87
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

452652:KSE RS36510
gene id: 452652:KSE_RS36510
uniprot id: E4NJI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

452652:KSE RS20405
gene id: 452652:KSE_RS20405
uniprot id: E4MZJ6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452652:KSE RS06735
gene id: 452652:KSE_RS06735
uniprot id: E4N7N7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS22265
gene id: 452652:KSE_RS22265
uniprot id: E4NFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS27580
gene id: 452652:KSE_RS27580
uniprot id: E4N020
names: Similarity
messages: Belongs to the CdaR family.

452652:KSE RS24245
gene id: 452652:KSE_RS24245
uniprot id: E4NGR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

452652:KSE RS35210
gene id: 452652:KSE_RS35210
uniprot id: E4NIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

452652:KSE RS27665
gene id: 452652:KSE_RS27665
uniprot id: E4N037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS08545
gene id: 452652:KSE_RS08545
uniprot id: E4N8N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS27535
gene id: 452652:KSE_RS27535
uniprot id: E4N011
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

452652:KSE RS10380
gene id: 452652:KSE_RS10380
uniprot id: E4N9Q2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

452652:KSE RS28630
gene id: 452652:KSE_RS28630
uniprot id: E4N3S7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

452652:KSE RS38390
gene id: 452652:KSE_RS38390
uniprot id: E4NBU1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS11410
gene id: 452652:KSE_RS11410
uniprot id: E4NAB2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452652:KSE RS13790
gene id: 452652:KSE_RS13790
uniprot id: E4NBN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

452652:KSE RS09970
gene id: 452652:KSE_RS09970
uniprot id: E4N9H1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15585
gene id: 452652:KSE_RS15585
uniprot id: E4NCN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

452652:KSE RS25080
gene id: 452652:KSE_RS25080
uniprot id: E4NH79
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

452652:KSE RS10460
gene id: 452652:KSE_RS10460
uniprot id: E4N9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

452652:KSE RS16630
gene id: 452652:KSE_RS16630
uniprot id: E4ND95
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

452652:KSE RS35085
gene id: 452652:KSE_RS35085
uniprot id: E4NIQ3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS25975
gene id: 452652:KSE_RS25975
uniprot id: E4NHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

452652:KSE RS10610
gene id: 452652:KSE_RS10610
uniprot id: E4N9U8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

452652:KSE RS11545
gene id: 452652:KSE_RS11545
uniprot id: E4NAD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

452652:KSE RS28260
gene id: 452652:KSE_RS28260
uniprot id: E4N3K6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

452652:KSE RS16690
gene id: 452652:KSE_RS16690
uniprot id: E4NDA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

452652:KSE RS31355
gene id: 452652:KSE_RS31355
uniprot id: E4N1R8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

452652:KSE RS16600
gene id: 452652:KSE_RS16600
uniprot id: E4ND89
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

452652:KSE RS13795
gene id: 452652:KSE_RS13795
uniprot id: E4NBN2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

452652:KSE RS19835
gene id: 452652:KSE_RS19835
uniprot id: E4NEM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

452652:KSE RS10165
gene id: 452652:KSE_RS10165
uniprot id: E4N9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

452652:KSE RS07350
gene id: 452652:KSE_RS07350
uniprot id: E4N803
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS32970
gene id: 452652:KSE_RS32970
uniprot id: E4N2P3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

452652:KSE RS19070
gene id: 452652:KSE_RS19070
uniprot id: E4MZ87
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

452652:KSE RS10555
gene id: 452652:KSE_RS10555
uniprot id: E4N9T7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS03135
gene id: 452652:KSE_RS03135
uniprot id: E4N5L5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS07710
gene id: 452652:KSE_RS07710
uniprot id: E4N872
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS34070
gene id: 452652:KSE_RS34070
uniprot id: E4N3B5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

452652:KSE RS24705
gene id: 452652:KSE_RS24705
uniprot id: E4NH04
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

452652:KSE RS00905
gene id: 452652:KSE_RS00905
uniprot id: E4N4A8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

452652:KSE RS05105
gene id: 452652:KSE_RS05105
uniprot id: E4N6Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UbiD family. UbiD-like/FDC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the reversible decarboxylation of aromatic carboxylic acids.
messages: Homodimer.

452652:KSE RS10695
gene id: 452652:KSE_RS10695
uniprot id: E4N9W6
names: Similarity
messages: Belongs to the peptidase C40 family.

452652:KSE RS26520
gene id: 452652:KSE_RS26520
uniprot id: E4NI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS25400
gene id: 452652:KSE_RS25400
uniprot id: E4NHD9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

452652:KSE RS24690
gene id: 452652:KSE_RS24690
uniprot id: E4NH01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS25135
gene id: 452652:KSE_RS25135
uniprot id: E4NH90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS36560
gene id: 452652:KSE_RS36560
uniprot id: E4NJJ9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS35720
gene id: 452652:KSE_RS35720
uniprot id: E4NJ30
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS19190
gene id: 452652:KSE_RS19190
uniprot id: E4MZB0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

452652:KSE RS17740
gene id: 452652:KSE_RS17740
uniprot id: E4NDW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

452652:KSE RS26100
gene id: 452652:KSE_RS26100
uniprot id: E4NHS8
names: Similarity
messages: Belongs to the IMPACT family.

452652:KSE RS32940
gene id: 452652:KSE_RS32940
uniprot id: E4N2N7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

452652:KSE RS30305
gene id: 452652:KSE_RS30305
uniprot id: E4N158
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

452652:KSE RS06755
gene id: 452652:KSE_RS06755
uniprot id: E4N7P1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

452652:KSE RS24295
gene id: 452652:KSE_RS24295
uniprot id: E4NGS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

452652:KSE RS14290
gene id: 452652:KSE_RS14290
uniprot id: E4NBX9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS06890
gene id: 452652:KSE_RS06890
uniprot id: E4N7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

452652:KSE RS15185
gene id: 452652:KSE_RS15185
uniprot id: E4NCF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

452652:KSE RS08085
gene id: 452652:KSE_RS08085
uniprot id: E4N8E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

452652:KSE RS20975
gene id: 452652:KSE_RS20975
uniprot id: E4MZV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

452652:KSE RS28585
gene id: 452652:KSE_RS28585
uniprot id: E4N3R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS28770
gene id: 452652:KSE_RS28770
uniprot id: E4N3V4
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS14480
gene id: 452652:KSE_RS14480
uniprot id: E4NC15
names: Similarity
messages: Belongs to the PGI/PMI family.

452652:KSE RS06790
gene id: 452652:KSE_RS06790
uniprot id: E4N7P8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

452652:KSE RS25560
gene id: 452652:KSE_RS25560
uniprot id: E4NHH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

452652:KSE RS16800
gene id: 452652:KSE_RS16800
uniprot id: E4NDC9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

452652:KSE RS28915
gene id: 452652:KSE_RS28915
uniprot id: E4N3Y3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS09470
gene id: 452652:KSE_RS09470
uniprot id: E4N971
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS24125
gene id: 452652:KSE_RS24125
uniprot id: E4NGN9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS38675
gene id: 452652:KSE_RS38675
uniprot id: E4MZW1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452652:KSE RS31175
gene id: 452652:KSE_RS31175
uniprot id: E4N1N1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS12310
gene id: 452652:KSE_RS12310
uniprot id: E4NAU5
names: Similarity
messages: Belongs to the group II decarboxylase family.

452652:KSE RS02305
gene id: 452652:KSE_RS02305
uniprot id: E4N544
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

452652:KSE RS28740
gene id: 452652:KSE_RS28740
uniprot id: E4N3U8
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

452652:KSE RS01535
gene id: 452652:KSE_RS01535
uniprot id: E4N4N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

452652:KSE RS12785
gene id: 452652:KSE_RS12785
uniprot id: E4NB36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

452652:KSE RS03900
gene id: 452652:KSE_RS03900
uniprot id: E4N619
names: Similarity
messages: Belongs to the asparagine synthetase family.

452652:KSE RS23520
gene id: 452652:KSE_RS23520
uniprot id: E4NGB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS35555
gene id: 452652:KSE_RS35555
uniprot id: E4NIZ7
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

452652:KSE RS21855
gene id: 452652:KSE_RS21855
uniprot id: E4NFD6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

452652:KSE RS16760
gene id: 452652:KSE_RS16760
uniprot id: E4NDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS33040
gene id: 452652:KSE_RS33040
uniprot id: E4N2Q8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS29555
gene id: 452652:KSE_RS29555
uniprot id: E4N0Q6
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

452652:KSE RS30630
gene id: 452652:KSE_RS30630
uniprot id: E4N1C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS21725
gene id: 452652:KSE_RS21725
uniprot id: E4NFA9
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

452652:KSE RS33625
gene id: 452652:KSE_RS33625
uniprot id: E4N326
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS15010
gene id: 452652:KSE_RS15010
uniprot id: E4NCC1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

452652:KSE RS36585
gene id: 452652:KSE_RS36585
uniprot id: E4NJK4
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

452652:KSE RS25970
gene id: 452652:KSE_RS25970
uniprot id: E4NHQ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS10105
gene id: 452652:KSE_RS10105
uniprot id: E4N9J8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS13405
gene id: 452652:KSE_RS13405
uniprot id: E4NBF5
names: Similarity
messages: Belongs to the thioesterase family.

452652:KSE RS28905
gene id: 452652:KSE_RS28905
uniprot id: E4N3Y1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS00565
gene id: 452652:KSE_RS00565
uniprot id: E4N439
names: Similarity
messages: Belongs to the peptidase S8 family.

452652:KSE RS12965
gene id: 452652:KSE_RS12965
uniprot id: E4NB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS15270
gene id: 452652:KSE_RS15270
uniprot id: E4NCH5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

452652:KSE RS02155
gene id: 452652:KSE_RS02155
uniprot id: E4N514
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS28955
gene id: 452652:KSE_RS28955
uniprot id: E4N3Z2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

452652:KSE RS27205
gene id: 452652:KSE_RS27205
uniprot id: E4NIE3
names: Similarity
messages: Belongs to the peptidase M1 family.

452652:KSE RS22970
gene id: 452652:KSE_RS22970
uniprot id: E4NG08
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

452652:KSE RS07595
gene id: 452652:KSE_RS07595
uniprot id: E4N849
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

452652:KSE RS03595
gene id: 452652:KSE_RS03595
uniprot id: E4N5V8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS22170
gene id: 452652:KSE_RS22170
uniprot id: E4NFK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

452652:KSE RS35170
gene id: 452652:KSE_RS35170
uniprot id: E4NIS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

452652:KSE RS29725
gene id: 452652:KSE_RS29725
uniprot id: E4N0U1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS30300
gene id: 452652:KSE_RS30300
uniprot id: E4N157
names: Similarity
messages: Belongs to the HSP15 family.

452652:KSE RS36515
gene id: 452652:KSE_RS36515
uniprot id: E4NJJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

452652:KSE RS34750
gene id: 452652:KSE_RS34750
uniprot id: E4MYV0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS16785
gene id: 452652:KSE_RS16785
uniprot id: E4NDC6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

452652:KSE RS31605
gene id: 452652:KSE_RS31605
uniprot id: E4N1W9
names: Similarity
messages: Belongs to the CdaR family.

452652:KSE RS23050
gene id: 452652:KSE_RS23050
uniprot id: E4NG24
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS33520
gene id: 452652:KSE_RS33520
uniprot id: E4N305
names: Similarity
messages: Belongs to the YciI family.

452652:KSE RS09760
gene id: 452652:KSE_RS09760
uniprot id: E4N9C8
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS25645
gene id: 452652:KSE_RS25645
uniprot id: E4NHJ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

452652:KSE RS12945
gene id: 452652:KSE_RS12945
uniprot id: E4NB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

452652:KSE RS16270
gene id: 452652:KSE_RS16270
uniprot id: E4ND22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS27465
gene id: 452652:KSE_RS27465
uniprot id: E4MZZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

452652:KSE RS18875
gene id: 452652:KSE_RS18875
uniprot id: E4MZ50
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS07235
gene id: 452652:KSE_RS07235
uniprot id: E4N7Y0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

452652:KSE RS24575
gene id: 452652:KSE_RS24575
uniprot id: E4NGX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS24785
gene id: 452652:KSE_RS24785
uniprot id: E4NH20
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

452652:KSE RS22540
gene id: 452652:KSE_RS22540
uniprot id: E4NFS5
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09550
gene id: 452652:KSE_RS09550
uniprot id: E4N988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS23635
gene id: 452652:KSE_RS23635
uniprot id: E4NGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

452652:KSE RS34235
gene id: 452652:KSE_RS34235
uniprot id: E4N3E8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

452652:KSE RS30570
gene id: 452652:KSE_RS30570
uniprot id: E4N1B3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

452652:KSE RS10205
gene id: 452652:KSE_RS10205
uniprot id: E4N9L8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS28960
gene id: 452652:KSE_RS28960
uniprot id: E4N3Z3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS10030
gene id: 452652:KSE_RS10030
uniprot id: E4N9I2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452652:KSE RS07215
gene id: 452652:KSE_RS07215
uniprot id: E4N7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

452652:KSE RS33250
gene id: 452652:KSE_RS33250
uniprot id: E4N2V0
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

452652:KSE RS36645
gene id: 452652:KSE_RS36645
uniprot id: E4NJL6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

452652:KSE RS15505
gene id: 452652:KSE_RS15505
uniprot id: E4NCM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

452652:KSE RS05495
gene id: 452652:KSE_RS05495
uniprot id: E4N6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

452652:KSE RS33515
gene id: 452652:KSE_RS33515
uniprot id: E4N304
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS27200
gene id: 452652:KSE_RS27200
uniprot id: E4NIE2
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS06945
gene id: 452652:KSE_RS06945
uniprot id: E4N7S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS36685
gene id: 452652:KSE_RS36685
uniprot id: E4NJM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

452652:KSE RS27505
gene id: 452652:KSE_RS27505
uniprot id: E4N005
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452652:KSE RS24990
gene id: 452652:KSE_RS24990
uniprot id: E4NH61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

452652:KSE RS18255
gene id: 452652:KSE_RS18255
uniprot id: E4NE72
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

452652:KSE RS23845
gene id: 452652:KSE_RS23845
uniprot id: E4NGI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

452652:KSE RS26855
gene id: 452652:KSE_RS26855
uniprot id: E4NI76
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

452652:KSE RS12150
gene id: 452652:KSE_RS12150
uniprot id: E4NAR6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

452652:KSE RS25985
gene id: 452652:KSE_RS25985
uniprot id: E4NHQ8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

452652:KSE RS07075
gene id: 452652:KSE_RS07075
uniprot id: E4N7V5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS06360
gene id: 452652:KSE_RS06360
uniprot id: E4N7G1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS16805
gene id: 452652:KSE_RS16805
uniprot id: E4NDD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS30540
gene id: 452652:KSE_RS30540
uniprot id: E4N1A7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

452652:KSE RS21720
gene id: 452652:KSE_RS21720
uniprot id: E4NFA8
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

452652:KSE RS33720
gene id: 452652:KSE_RS33720
uniprot id: E4N345
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS10335
gene id: 452652:KSE_RS10335
uniprot id: E4N9P4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

452652:KSE RS09690
gene id: 452652:KSE_RS09690
uniprot id: E4N9B6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09130
gene id: 452652:KSE_RS09130
uniprot id: E4N903
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

452652:KSE RS14200
gene id: 452652:KSE_RS14200
uniprot id: E4NBW1
names: Similarity
messages: Belongs to the malic enzymes family.

452652:KSE RS29235
gene id: 452652:KSE_RS29235
uniprot id: E4N0J2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS26155
gene id: 452652:KSE_RS26155
uniprot id: E4NHT9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS10780
gene id: 452652:KSE_RS10780
uniprot id: E4N9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

452652:KSE RS19790
gene id: 452652:KSE_RS19790
uniprot id: E4NEM0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

452652:KSE RS01090
gene id: 452652:KSE_RS01090
uniprot id: E4N4E5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

452652:KSE RS00780
gene id: 452652:KSE_RS00780
uniprot id: E4N481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS15625
gene id: 452652:KSE_RS15625
uniprot id: E4NCP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

452652:KSE RS17025
gene id: 452652:KSE_RS17025
uniprot id: E4NDH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS17800
gene id: 452652:KSE_RS17800
uniprot id: E4NDY1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS14820
gene id: 452652:KSE_RS14820
uniprot id: E4NC85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

452652:KSE RS18965
gene id: 452652:KSE_RS18965
uniprot id: E4MZ68
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

452652:KSE RS33980
gene id: 452652:KSE_RS33980
uniprot id: E4N397
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

452652:KSE RS37240
gene id: 452652:KSE_RS37240
uniprot id: E4NJY5
names: Similarity
messages: Belongs to the TPP enzyme family.

452652:KSE RS18815
gene id: 452652:KSE_RS18815
uniprot id: E4NEI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

452652:KSE RS19505
gene id: 452652:KSE_RS19505
uniprot id: E4MZH2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS11540
gene id: 452652:KSE_RS11540
uniprot id: E4NAD8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS17545
gene id: 452652:KSE_RS17545
uniprot id: E4NDS9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

452652:KSE RS26850
gene id: 452652:KSE_RS26850
uniprot id: E4NI75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS07240
gene id: 452652:KSE_RS07240
uniprot id: E4N7Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

452652:KSE RS24750
gene id: 452652:KSE_RS24750
uniprot id: E4NH13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

452652:KSE RS28175
gene id: 452652:KSE_RS28175
uniprot id: E4N0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

452652:KSE RS25315
gene id: 452652:KSE_RS25315
uniprot id: E4NHC6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

452652:KSE RS01740
gene id: 452652:KSE_RS01740
uniprot id: E4N4S9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS08880
gene id: 452652:KSE_RS08880
uniprot id: E4N8V1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

452652:KSE RS17475
gene id: 452652:KSE_RS17475
uniprot id: E4NDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

452652:KSE RS35490
gene id: 452652:KSE_RS35490
uniprot id: E4NIY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

452652:KSE RS20715
gene id: 452652:KSE_RS20715
uniprot id: E4MZQ3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452652:KSE RS27430
gene id: 452652:KSE_RS27430
uniprot id: E4MZZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452652:KSE RS02030
gene id: 452652:KSE_RS02030
uniprot id: E4N4Y8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09460
gene id: 452652:KSE_RS09460
uniprot id: E4N969
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS05005
gene id: 452652:KSE_RS05005
uniprot id: E4N6N5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

452652:KSE RS26390
gene id: 452652:KSE_RS26390
uniprot id: E4NHY3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS24745
gene id: 452652:KSE_RS24745
uniprot id: E4NH12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

452652:KSE RS33345
gene id: 452652:KSE_RS33345
uniprot id: E4N2W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452652:KSE RS13270
gene id: 452652:KSE_RS13270
uniprot id: E4NBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS10485
gene id: 452652:KSE_RS10485
uniprot id: E4N9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

452652:KSE RS10735
gene id: 452652:KSE_RS10735
uniprot id: E4N9X4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS28270
gene id: 452652:KSE_RS28270
uniprot id: E4N3K8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

452652:KSE RS28395
gene id: 452652:KSE_RS28395
uniprot id: E4N3M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS27440
gene id: 452652:KSE_RS27440
uniprot id: E4MZZ2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

452652:KSE RS38715
gene id: 452652:KSE_RS38715
uniprot id: E4NFP6
names: Similarity
messages: Belongs to the peptidase S11 family.

452652:KSE RS15490
gene id: 452652:KSE_RS15490
uniprot id: E4NCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

452652:KSE RS15305
gene id: 452652:KSE_RS15305
uniprot id: E4NCI2
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

452652:KSE RS23760
gene id: 452652:KSE_RS23760
uniprot id: E4NGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS21745
gene id: 452652:KSE_RS21745
uniprot id: E4NFB3
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS13445
gene id: 452652:KSE_RS13445
uniprot id: E4NBG3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS15620
gene id: 452652:KSE_RS15620
uniprot id: E4NCP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

452652:KSE RS33030
gene id: 452652:KSE_RS33030
uniprot id: E4N2Q6
names: Similarity
messages: Belongs to the proline racemase family.

452652:KSE RS36295
gene id: 452652:KSE_RS36295
uniprot id: E4NJE6
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

452652:KSE RS27015
gene id: 452652:KSE_RS27015
uniprot id: E4NIA4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

452652:KSE RS27930
gene id: 452652:KSE_RS27930
uniprot id: E4N092
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS30115
gene id: 452652:KSE_RS30115
uniprot id: E4N120
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

452652:KSE RS05715
gene id: 452652:KSE_RS05715
uniprot id: E4N727
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15335
gene id: 452652:KSE_RS15335
uniprot id: E4NCI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

452652:KSE RS09555
gene id: 452652:KSE_RS09555
uniprot id: E4N989
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS17355
gene id: 452652:KSE_RS17355
uniprot id: E4NDP1
names: Similarity
messages: Belongs to the heat shock protein 90 family.

452652:KSE RS15340
gene id: 452652:KSE_RS15340
uniprot id: E4NCI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

452652:KSE RS37590
gene id: 452652:KSE_RS37590
uniprot id: E4MZ30
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

452652:KSE RS16505
gene id: 452652:KSE_RS16505
uniprot id: E4ND70
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

452652:KSE RS24545
gene id: 452652:KSE_RS24545
uniprot id: E4NGX3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

452652:KSE RS11520
gene id: 452652:KSE_RS11520
uniprot id: E4NAD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS02540
gene id: 452652:KSE_RS02540
uniprot id: E4N596
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS22255
gene id: 452652:KSE_RS22255
uniprot id: E4NFL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS14115
gene id: 452652:KSE_RS14115
uniprot id: E4NBU6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS16255
gene id: 452652:KSE_RS16255
uniprot id: E4ND19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

452652:KSE RS06125
gene id: 452652:KSE_RS06125
uniprot id: E4N7B0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS21030
gene id: 452652:KSE_RS21030
uniprot id: E4MZW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

452652:KSE RS23370
gene id: 452652:KSE_RS23370
uniprot id: E4NG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452652:KSE RS14630
gene id: 452652:KSE_RS14630
uniprot id: E4NC46
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS24635
gene id: 452652:KSE_RS24635
uniprot id: E4NGZ1
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS05675
gene id: 452652:KSE_RS05675
uniprot id: E4N719
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS01875
gene id: 452652:KSE_RS01875
uniprot id: E4N4V7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS27685
gene id: 452652:KSE_RS27685
uniprot id: E4N041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS12620
gene id: 452652:KSE_RS12620
uniprot id: E4NB07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

452652:KSE RS09800
gene id: 452652:KSE_RS09800
uniprot id: E4N9D7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

452652:KSE RS06780
gene id: 452652:KSE_RS06780
uniprot id: E4N7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

452652:KSE RS15880
gene id: 452652:KSE_RS15880
uniprot id: E4NCU5
names: Similarity
messages: Belongs to the UPF0336 family.

452652:KSE RS31405
gene id: 452652:KSE_RS31405
uniprot id: E4N1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

452652:KSE RS04860
gene id: 452652:KSE_RS04860
uniprot id: E4N6K7
names: Similarity
messages: Belongs to the universal stress protein A family.

452652:KSE RS28110
gene id: 452652:KSE_RS28110
uniprot id: E4N0C8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15310
gene id: 452652:KSE_RS15310
uniprot id: E4NCI3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

452652:KSE RS22300
gene id: 452652:KSE_RS22300
uniprot id: E4NFM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS06960
gene id: 452652:KSE_RS06960
uniprot id: E4N7T2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

452652:KSE RS27590
gene id: 452652:KSE_RS27590
uniprot id: E4N022
names: Cofactor
messages: Binds 1 FAD per subunit.

452652:KSE RS23975
gene id: 452652:KSE_RS23975
uniprot id: E4NGK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

452652:KSE RS20165
gene id: 452652:KSE_RS20165
uniprot id: E4NEU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS13065
gene id: 452652:KSE_RS13065
uniprot id: E4NB91
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS21430
gene id: 452652:KSE_RS21430
uniprot id: E4NF49
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

452652:KSE RS12155
gene id: 452652:KSE_RS12155
uniprot id: E4NAR7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS31390
gene id: 452652:KSE_RS31390
uniprot id: E4N1S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

452652:KSE RS14710
gene id: 452652:KSE_RS14710
uniprot id: E4NC63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

452652:KSE RS15720
gene id: 452652:KSE_RS15720
uniprot id: E4NCR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

452652:KSE RS23540
gene id: 452652:KSE_RS23540
uniprot id: E4NGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

452652:KSE RS12500
gene id: 452652:KSE_RS12500
uniprot id: E4NAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

452652:KSE RS23605
gene id: 452652:KSE_RS23605
uniprot id: E4NGD3
names: Similarity
messages: Belongs to the FBPase class 2 family.

452652:KSE RS20065
gene id: 452652:KSE_RS20065
uniprot id: E4NES5
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS28265
gene id: 452652:KSE_RS28265
uniprot id: E4N3K7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS18090
gene id: 452652:KSE_RS18090
uniprot id: E4NE39
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

452652:KSE RS08720
gene id: 452652:KSE_RS08720
uniprot id: E4N8R9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS03880
gene id: 452652:KSE_RS03880
uniprot id: E4N615
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

452652:KSE RS18925
gene id: 452652:KSE_RS18925
uniprot id: E4MZ60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS07455
gene id: 452652:KSE_RS07455
uniprot id: E4N824
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS33130
gene id: 452652:KSE_RS33130
uniprot id: E4N2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS35850
gene id: 452652:KSE_RS35850
uniprot id: E4NJ56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Belongs to the AccA family.
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

452652:KSE RS21405
gene id: 452652:KSE_RS21405
uniprot id: E4NF44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

452652:KSE RS21385
gene id: 452652:KSE_RS21385
uniprot id: E4NF40
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452652:KSE RS04750
gene id: 452652:KSE_RS04750
uniprot id: E4N6I5
names: Similarity
messages: Belongs to the DNA photolyase family.

452652:KSE RS35380
gene id: 452652:KSE_RS35380
uniprot id: E4NIW3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS33180
gene id: 452652:KSE_RS33180
uniprot id: E4N2T6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15485
gene id: 452652:KSE_RS15485
uniprot id: E4NCL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

452652:KSE RS22600
gene id: 452652:KSE_RS22600
uniprot id: E4NFT6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

452652:KSE RS24260
gene id: 452652:KSE_RS24260
uniprot id: E4NGR6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

452652:KSE RS10010
gene id: 452652:KSE_RS10010
uniprot id: E4N9H8
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

452652:KSE RS26170
gene id: 452652:KSE_RS26170
uniprot id: E4NHU2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452652:KSE RS33885
gene id: 452652:KSE_RS33885
uniprot id: E4N378
names: Similarity
messages: Belongs to the CsoR family.

452652:KSE RS32790
gene id: 452652:KSE_RS32790
uniprot id: E4N2K7
names: Similarity
messages: Belongs to the TPP enzyme family.

452652:KSE RS38480
gene id: 452652:KSE_RS38480
uniprot id: E4NCM6
names: Similarity
messages: Belongs to the stealth family.

452652:KSE RS10170
gene id: 452652:KSE_RS10170
uniprot id: E4N9L1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

452652:KSE RS21610
gene id: 452652:KSE_RS21610
uniprot id: E4NF86
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

452652:KSE RS12755
gene id: 452652:KSE_RS12755
uniprot id: E4NB30
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

452652:KSE RS15410
gene id: 452652:KSE_RS15410
uniprot id: E4NCK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS10440
gene id: 452652:KSE_RS10440
uniprot id: E4N9R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

452652:KSE RS01890
gene id: 452652:KSE_RS01890
uniprot id: E4N4W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

452652:KSE RS20875
gene id: 452652:KSE_RS20875
uniprot id: E4MZT6
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.
messages: Homodimer.

452652:KSE RS30645
gene id: 452652:KSE_RS30645
uniprot id: E4N1C8
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

452652:KSE RS25595
gene id: 452652:KSE_RS25595
uniprot id: E4NHI0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

452652:KSE RS22560
gene id: 452652:KSE_RS22560
uniprot id: E4NFS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

452652:KSE RS28195
gene id: 452652:KSE_RS28195
uniprot id: E4N0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

452652:KSE RS05020
gene id: 452652:KSE_RS05020
uniprot id: E4N6N8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS23880
gene id: 452652:KSE_RS23880
uniprot id: E4NGI8
names: Similarity
messages: Belongs to the UPF0162 family.

452652:KSE RS32995
gene id: 452652:KSE_RS32995
uniprot id: E4N2P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

452652:KSE RS05140
gene id: 452652:KSE_RS05140
uniprot id: E4N6R1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS24240
gene id: 452652:KSE_RS24240
uniprot id: E4NGR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS15575
gene id: 452652:KSE_RS15575
uniprot id: E4NCN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

452652:KSE RS13890
gene id: 452652:KSE_RS13890
uniprot id: E4NBQ0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS19565
gene id: 452652:KSE_RS19565
uniprot id: E4MZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

452652:KSE RS01900
gene id: 452652:KSE_RS01900
uniprot id: E4N4W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS10070
gene id: 452652:KSE_RS10070
uniprot id: E4N9J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

452652:KSE RS24905
gene id: 452652:KSE_RS24905
uniprot id: E4NH44
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS02780
gene id: 452652:KSE_RS02780
uniprot id: E4N5E4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

452652:KSE RS14875
gene id: 452652:KSE_RS14875
uniprot id: E4NC96
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS32100
gene id: 452652:KSE_RS32100
uniprot id: E4N270
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

452652:KSE RS16280
gene id: 452652:KSE_RS16280
uniprot id: E4ND24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

452652:KSE RS06145
gene id: 452652:KSE_RS06145
uniprot id: E4N7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

452652:KSE RS30600
gene id: 452652:KSE_RS30600
uniprot id: E4N1B9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452652:KSE RS02365
gene id: 452652:KSE_RS02365
uniprot id: E4N556
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS11905
gene id: 452652:KSE_RS11905
uniprot id: E4NAL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452652:KSE RS33795
gene id: 452652:KSE_RS33795
uniprot id: E4N360
names: Similarity
messages: Belongs to the HIBADH-related family.

452652:KSE RS23510
gene id: 452652:KSE_RS23510
uniprot id: E4NGB5
names: Similarity
messages: Belongs to the peptidase A24 family.

452652:KSE RS10660
gene id: 452652:KSE_RS10660
uniprot id: E4N9V9
names: Similarity
messages: Belongs to the arsA ATPase family.

452652:KSE RS30200
gene id: 452652:KSE_RS30200
uniprot id: E4N136
names: Similarity
messages: Belongs to the peptidase C40 family.

452652:KSE RS13195
gene id: 452652:KSE_RS13195
uniprot id: E4NBB4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

452652:KSE RS32150
gene id: 452652:KSE_RS32150
uniprot id: E4N280
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS03050
gene id: 452652:KSE_RS03050
uniprot id: E4N5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

452652:KSE RS33495
gene id: 452652:KSE_RS33495
uniprot id: E4N300
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS27180
gene id: 452652:KSE_RS27180
uniprot id: E4NID8
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

452652:KSE RS14810
gene id: 452652:KSE_RS14810
uniprot id: E4NC83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452652:KSE RS00375
gene id: 452652:KSE_RS00375
uniprot id: E4MZ36
names: Similarity
messages: Belongs to the phosphohexose mutase family.

452652:KSE RS24310
gene id: 452652:KSE_RS24310
uniprot id: E4NGS6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

452652:KSE RS23935
gene id: 452652:KSE_RS23935
uniprot id: E4NGJ9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

452652:KSE RS07650
gene id: 452652:KSE_RS07650
uniprot id: E4N860
names: Similarity
messages: Belongs to the serpin family.

452652:KSE RS26675
gene id: 452652:KSE_RS26675
uniprot id: E4NI40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

452652:KSE RS38430
gene id: 452652:KSE_RS38430
uniprot id: E4NC94
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS18010
gene id: 452652:KSE_RS18010
uniprot id: E4NE23
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS20475
gene id: 452652:KSE_RS20475
uniprot id: E4MZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

452652:KSE RS19295
gene id: 452652:KSE_RS19295
uniprot id: E4MZD1
names: Similarity
messages: Belongs to the thioredoxin family.

452652:KSE RS05480
gene id: 452652:KSE_RS05480
uniprot id: E4N6Y0
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS15440
gene id: 452652:KSE_RS15440
uniprot id: E4NCK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

452652:KSE RS26730
gene id: 452652:KSE_RS26730
uniprot id: E4NI51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

452652:KSE RS21960
gene id: 452652:KSE_RS21960
uniprot id: E4NFF8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

452652:KSE RS13425
gene id: 452652:KSE_RS13425
uniprot id: E4NBF9
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS28490
gene id: 452652:KSE_RS28490
uniprot id: E4N3P8
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

452652:KSE RS11135
gene id: 452652:KSE_RS11135
uniprot id: E4NA56
names: Similarity
names: Subunit
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. SbnA subfamily.
messages: Homodimer.

452652:KSE RS14355
gene id: 452652:KSE_RS14355
uniprot id: E4NBZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

452652:KSE RS30455
gene id: 452652:KSE_RS30455
uniprot id: E4N190
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS35195
gene id: 452652:KSE_RS35195
uniprot id: E4NIS5
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS05615
gene id: 452652:KSE_RS05615
uniprot id: E4N707
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS26465
gene id: 452652:KSE_RS26465
uniprot id: E4NHZ8
names: Similarity
messages: Belongs to the peptidase S8 family.

452652:KSE RS06980
gene id: 452652:KSE_RS06980
uniprot id: E4N7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS24205
gene id: 452652:KSE_RS24205
uniprot id: E4NGQ6
names: Similarity
messages: Belongs to the peptidase S16 family.

452652:KSE RS30475
gene id: 452652:KSE_RS30475
uniprot id: E4N194
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS18225
gene id: 452652:KSE_RS18225
uniprot id: E4NE66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452652:KSE RS30160
gene id: 452652:KSE_RS30160
uniprot id: E4N129
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

452652:KSE RS06670
gene id: 452652:KSE_RS06670
uniprot id: E4N7M4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

452652:KSE RS09105
gene id: 452652:KSE_RS09105
uniprot id: E4N8Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS24350
gene id: 452652:KSE_RS24350
uniprot id: E4NGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS22225
gene id: 452652:KSE_RS22225
uniprot id: E4NFL3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

452652:KSE RS26795
gene id: 452652:KSE_RS26795
uniprot id: E4NI64
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

452652:KSE RS22310
gene id: 452652:KSE_RS22310
uniprot id: E4NFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

452652:KSE RS08655
gene id: 452652:KSE_RS08655
uniprot id: E4N8Q7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

452652:KSE RS05830
gene id: 452652:KSE_RS05830
uniprot id: E4N750
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

452652:KSE RS14385
gene id: 452652:KSE_RS14385
uniprot id: E4NBZ9
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS23515
gene id: 452652:KSE_RS23515
uniprot id: E4NGB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

452652:KSE RS22385
gene id: 452652:KSE_RS22385
uniprot id: E4NFP5
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS07375
gene id: 452652:KSE_RS07375
uniprot id: E4N808
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS08635
gene id: 452652:KSE_RS08635
uniprot id: E4N8Q3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

452652:KSE RS27070
gene id: 452652:KSE_RS27070
uniprot id: E4NIB5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

452652:KSE RS05630
gene id: 452652:KSE_RS05630
uniprot id: E4N710
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

452652:KSE RS35100
gene id: 452652:KSE_RS35100
uniprot id: E4NIQ6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS21550
gene id: 452652:KSE_RS21550
uniprot id: E4NF74
names: Similarity
messages: Belongs to the Fur family.

452652:KSE RS27750
gene id: 452652:KSE_RS27750
uniprot id: E4N054
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

452652:KSE RS26310
gene id: 452652:KSE_RS26310
uniprot id: E4NHX0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS14220
gene id: 452652:KSE_RS14220
uniprot id: E4NBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

452652:KSE RS12905
gene id: 452652:KSE_RS12905
uniprot id: E4NB60
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

452652:KSE RS11230
gene id: 452652:KSE_RS11230
uniprot id: E4NA76
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS07285
gene id: 452652:KSE_RS07285
uniprot id: E4N7Z0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

452652:KSE RS07055
gene id: 452652:KSE_RS07055
uniprot id: E4N7V1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

452652:KSE RS08440
gene id: 452652:KSE_RS08440
uniprot id: E4N8L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

452652:KSE RS14550
gene id: 452652:KSE_RS14550
uniprot id: E4NC29
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452652:KSE RS32825
gene id: 452652:KSE_RS32825
uniprot id: E4N2L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

452652:KSE RS20430
gene id: 452652:KSE_RS20430
uniprot id: E4MZK1
names: Similarity
messages: Belongs to the peptidase M18 family.

452652:KSE RS22480
gene id: 452652:KSE_RS22480
uniprot id: E4NFR3
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS22400
gene id: 452652:KSE_RS22400
uniprot id: E4NFP7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS13945
gene id: 452652:KSE_RS13945
uniprot id: E4NBR2
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

452652:KSE RS09500
gene id: 452652:KSE_RS09500
uniprot id: E4N977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

452652:KSE RS28050
gene id: 452652:KSE_RS28050
uniprot id: E4N0B6
names: Similarity
messages: Belongs to the peptidase S8 family.

452652:KSE RS24835
gene id: 452652:KSE_RS24835
uniprot id: E4NH30
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS26970
gene id: 452652:KSE_RS26970
uniprot id: E4NI96
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

452652:KSE RS35285
gene id: 452652:KSE_RS35285
uniprot id: E4NIU3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452652:KSE RS33330
gene id: 452652:KSE_RS33330
uniprot id: E4N2W6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

452652:KSE RS21390
gene id: 452652:KSE_RS21390
uniprot id: E4NF41
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

452652:KSE RS15680
gene id: 452652:KSE_RS15680
uniprot id: E4NCQ6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

452652:KSE RS30840
gene id: 452652:KSE_RS30840
uniprot id: E4N1G5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

452652:KSE RS15590
gene id: 452652:KSE_RS15590
uniprot id: E4NCN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

452652:KSE RS07010
gene id: 452652:KSE_RS07010
uniprot id: E4N7U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

452652:KSE RS03160
gene id: 452652:KSE_RS03160
uniprot id: E4N5M0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452652:KSE RS01810
gene id: 452652:KSE_RS01810
uniprot id: E4N4U3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS29200
gene id: 452652:KSE_RS29200
uniprot id: E4N0I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

452652:KSE RS03930
gene id: 452652:KSE_RS03930
uniprot id: E4N625
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

452652:KSE RS24680
gene id: 452652:KSE_RS24680
uniprot id: E4NGZ9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

452652:KSE RS14455
gene id: 452652:KSE_RS14455
uniprot id: E4NC11
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS19655
gene id: 452652:KSE_RS19655
uniprot id: E4NEJ0
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

452652:KSE RS11450
gene id: 452652:KSE_RS11450
uniprot id: E4NAC0
names: Similarity
messages: Belongs to the P(II) protein family.

452652:KSE RS11945
gene id: 452652:KSE_RS11945
uniprot id: E4NAM4
names: Similarity
messages: Belongs to the barstar family.

452652:KSE RS07250
gene id: 452652:KSE_RS07250
uniprot id: E4N7Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

452652:KSE RS00345
gene id: 452652:KSE_RS00345
uniprot id: E4MZ30
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

452652:KSE RS25615
gene id: 452652:KSE_RS25615
uniprot id: E4NHI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS17865
gene id: 452652:KSE_RS17865
uniprot id: E4NDZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

452652:KSE RS34935
gene id: 452652:KSE_RS34935
uniprot id: E4NIM3
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS29750
gene id: 452652:KSE_RS29750
uniprot id: E4N0U6
names: Subcellular Location Annotation
messages: Secreted

452652:KSE RS10155
gene id: 452652:KSE_RS10155
uniprot id: E4N9K8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

452652:KSE RS31040
gene id: 452652:KSE_RS31040
uniprot id: E4N1K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

452652:KSE RS10955
gene id: 452652:KSE_RS10955
uniprot id: E4NA18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

452652:KSE RS16680
gene id: 452652:KSE_RS16680
uniprot id: E4NDA5
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15715
gene id: 452652:KSE_RS15715
uniprot id: E4NCR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

452652:KSE RS06415
gene id: 452652:KSE_RS06415
uniprot id: E4N7H2
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS25300
gene id: 452652:KSE_RS25300
uniprot id: E4NHC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS13430
gene id: 452652:KSE_RS13430
uniprot id: E4NBG0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

452652:KSE RS21580
gene id: 452652:KSE_RS21580
uniprot id: E4NF80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

452652:KSE RS00475
gene id: 452652:KSE_RS00475
uniprot id: E4N418
names: Similarity
messages: Belongs to the phosphohexose mutase family.

452652:KSE RS12445
gene id: 452652:KSE_RS12445
uniprot id: E4NAX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS10385
gene id: 452652:KSE_RS10385
uniprot id: E4N9Q3
names: Similarity
messages: Belongs to the glutamate synthase family.

452652:KSE RS22995
gene id: 452652:KSE_RS22995
uniprot id: E4NG13
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

452652:KSE RS00370
gene id: 452652:KSE_RS00370
uniprot id: E4MZ35
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

452652:KSE RS27210
gene id: 452652:KSE_RS27210
uniprot id: E4NIE4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS20955
gene id: 452652:KSE_RS20955
uniprot id: E4MZV2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS27425
gene id: 452652:KSE_RS27425
uniprot id: E4MZY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

452652:KSE RS16795
gene id: 452652:KSE_RS16795
uniprot id: E4NDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

452652:KSE RS18545
gene id: 452652:KSE_RS18545
uniprot id: E4NEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

452652:KSE RS10850
gene id: 452652:KSE_RS10850
uniprot id: E4N9Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

452652:KSE RS27905
gene id: 452652:KSE_RS27905
uniprot id: E4N087
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452652:KSE RS25025
gene id: 452652:KSE_RS25025
uniprot id: E4NH68
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

452652:KSE RS05640
gene id: 452652:KSE_RS05640
uniprot id: E4N712
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

452652:KSE RS16155
gene id: 452652:KSE_RS16155
uniprot id: E4NCZ7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

452652:KSE RS14485
gene id: 452652:KSE_RS14485
uniprot id: E4NC16
names: Similarity
messages: Belongs to the UPF0434 family.

452652:KSE RS28320
gene id: 452652:KSE_RS28320
uniprot id: E4N3L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS00710
gene id: 452652:KSE_RS00710
uniprot id: E4N468
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

452652:KSE RS19825
gene id: 452652:KSE_RS19825
uniprot id: E4NEM7
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS10245
gene id: 452652:KSE_RS10245
uniprot id: E4N9M6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS07590
gene id: 452652:KSE_RS07590
uniprot id: E4N848
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

452652:KSE RS10700
gene id: 452652:KSE_RS10700
uniprot id: E4N9W7
names: Similarity
messages: Belongs to the peptidase C40 family.

452652:KSE RS26360
gene id: 452652:KSE_RS26360
uniprot id: E4NHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

452652:KSE RS10175
gene id: 452652:KSE_RS10175
uniprot id: E4N9L2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

452652:KSE RS20460
gene id: 452652:KSE_RS20460
uniprot id: E4MZK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

452652:KSE RS07510
gene id: 452652:KSE_RS07510
uniprot id: E4N835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

452652:KSE RS17990
gene id: 452652:KSE_RS17990
uniprot id: E4NE19
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS10445
gene id: 452652:KSE_RS10445
uniprot id: E4N9R5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS23815
gene id: 452652:KSE_RS23815
uniprot id: E4NGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS05055
gene id: 452652:KSE_RS05055
uniprot id: E4N6P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

452652:KSE RS17390
gene id: 452652:KSE_RS17390
uniprot id: E4NDP8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15565
gene id: 452652:KSE_RS15565
uniprot id: E4NCN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

452652:KSE RS22145
gene id: 452652:KSE_RS22145
uniprot id: E4NFJ7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS08195
gene id: 452652:KSE_RS08195
uniprot id: E4N8G8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

452652:KSE RS07680
gene id: 452652:KSE_RS07680
uniprot id: E4N866
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS19335
gene id: 452652:KSE_RS19335
uniprot id: E4MZE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

452652:KSE RS21950
gene id: 452652:KSE_RS21950
uniprot id: E4NFF6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS10405
gene id: 452652:KSE_RS10405
uniprot id: E4N9Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

452652:KSE RS23040
gene id: 452652:KSE_RS23040
uniprot id: E4NG22
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

452652:KSE RS17260
gene id: 452652:KSE_RS17260
uniprot id: E4NDM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS15695
gene id: 452652:KSE_RS15695
uniprot id: E4NCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

452652:KSE RS03635
gene id: 452652:KSE_RS03635
uniprot id: E4N5W6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS07370
gene id: 452652:KSE_RS07370
uniprot id: E4N807
names: Similarity
messages: Belongs to the ketopantoate reductase family.

452652:KSE RS25320
gene id: 452652:KSE_RS25320
uniprot id: E4NHC7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

452652:KSE RS12530
gene id: 452652:KSE_RS12530
uniprot id: E4NAY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

452652:KSE RS37170
gene id: 452652:KSE_RS37170
uniprot id: E4NJX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

452652:KSE RS36205
gene id: 452652:KSE_RS36205
uniprot id: E4NJC8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

452652:KSE RS11265
gene id: 452652:KSE_RS11265
uniprot id: E4NA83
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09775
gene id: 452652:KSE_RS09775
uniprot id: E4N9D2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS01920
gene id: 452652:KSE_RS01920
uniprot id: E4N4W6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS05620
gene id: 452652:KSE_RS05620
uniprot id: E4N708
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15525
gene id: 452652:KSE_RS15525
uniprot id: E4NCM5
names: Similarity
messages: Belongs to the stealth family.

452652:KSE RS30970
gene id: 452652:KSE_RS30970
uniprot id: E4N1J0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS15905
gene id: 452652:KSE_RS15905
uniprot id: E4NCU8
names: Similarity
messages: Belongs to the UPF0234 family.

452652:KSE RS26210
gene id: 452652:KSE_RS26210
uniprot id: E4NHV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

452652:KSE RS37285
gene id: 452652:KSE_RS37285
uniprot id: E4NJZ5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

452652:KSE RS29875
gene id: 452652:KSE_RS29875
uniprot id: E4N0X3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS10800
gene id: 452652:KSE_RS10800
uniprot id: E4N9Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

452652:KSE RS07505
gene id: 452652:KSE_RS07505
uniprot id: E4N834
names: Similarity
messages: Belongs to the phosphohexose mutase family.

452652:KSE RS02920
gene id: 452652:KSE_RS02920
uniprot id: E4N5H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

452652:KSE RS18690
gene id: 452652:KSE_RS18690
uniprot id: E4NEF5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

452652:KSE RS19240
gene id: 452652:KSE_RS19240
uniprot id: E4MZC0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

452652:KSE RS34850
gene id: 452652:KSE_RS34850
uniprot id: E4NIK6
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS22285
gene id: 452652:KSE_RS22285
uniprot id: E4NFM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

452652:KSE RS13760
gene id: 452652:KSE_RS13760
uniprot id: E4NBM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS02975
gene id: 452652:KSE_RS02975
uniprot id: E4N5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS10140
gene id: 452652:KSE_RS10140
uniprot id: E4N9K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

452652:KSE RS14025
gene id: 452652:KSE_RS14025
uniprot id: E4NBS8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS26710
gene id: 452652:KSE_RS26710
uniprot id: E4NI47
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452652:KSE RS22880
gene id: 452652:KSE_RS22880
uniprot id: E4NFZ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS23125
gene id: 452652:KSE_RS23125
uniprot id: E4NG39
names: Similarity
messages: Belongs to the CutA family.

452652:KSE RS15460
gene id: 452652:KSE_RS15460
uniprot id: E4NCL2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

452652:KSE RS18120
gene id: 452652:KSE_RS18120
uniprot id: E4NE45
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

452652:KSE RS25115
gene id: 452652:KSE_RS25115
uniprot id: E4NH86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

452652:KSE RS31435
gene id: 452652:KSE_RS31435
uniprot id: E4N1T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

452652:KSE RS22430
gene id: 452652:KSE_RS22430
uniprot id: E4NFQ3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS23360
gene id: 452652:KSE_RS23360
uniprot id: E4NG84
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

452652:KSE RS21965
gene id: 452652:KSE_RS21965
uniprot id: E4NFF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

452652:KSE RS04100
gene id: 452652:KSE_RS04100
uniprot id: E4N658
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

452652:KSE RS37480
gene id: 452652:KSE_RS37480
uniprot id: E4N414
names: Similarity
messages: Belongs to the peptidase C56 family.

452652:KSE RS15595
gene id: 452652:KSE_RS15595
uniprot id: E4NCN9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

452652:KSE RS32230
gene id: 452652:KSE_RS32230
uniprot id: E4N296
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

452652:KSE RS18330
gene id: 452652:KSE_RS18330
uniprot id: E4NE88
names: Similarity
messages: Belongs to the UPF0098 family.

452652:KSE RS12890
gene id: 452652:KSE_RS12890
uniprot id: E4NB57
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

452652:KSE RS21595
gene id: 452652:KSE_RS21595
uniprot id: E4NF83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

452652:KSE RS16675
gene id: 452652:KSE_RS16675
uniprot id: E4NDA4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

452652:KSE RS12875
gene id: 452652:KSE_RS12875
uniprot id: E4NB54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

452652:KSE RS15560
gene id: 452652:KSE_RS15560
uniprot id: E4NCN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

452652:KSE RS08900
gene id: 452652:KSE_RS08900
uniprot id: E4N8V4
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

452652:KSE RS14915
gene id: 452652:KSE_RS14915
uniprot id: E4NCA3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS13865
gene id: 452652:KSE_RS13865
uniprot id: E4NBP5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

452652:KSE RS00455
gene id: 452652:KSE_RS00455
uniprot id: E4N414
names: Similarity
messages: Belongs to the peptidase C56 family.

452652:KSE RS17795
gene id: 452652:KSE_RS17795
uniprot id: E4NDY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

452652:KSE RS05135
gene id: 452652:KSE_RS05135
uniprot id: E4N6R0
names: Similarity
messages: Belongs to the FGGY kinase family.

452652:KSE RS31110
gene id: 452652:KSE_RS31110
uniprot id: E4N1L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS23285
gene id: 452652:KSE_RS23285
uniprot id: E4NG70
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

452652:KSE RS25415
gene id: 452652:KSE_RS25415
uniprot id: E4NHE2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

452652:KSE RS02240
gene id: 452652:KSE_RS02240
uniprot id: E4N530
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS25470
gene id: 452652:KSE_RS25470
uniprot id: E4NHF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS14980
gene id: 452652:KSE_RS14980
uniprot id: E4NCB5
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

452652:KSE RS26435
gene id: 452652:KSE_RS26435
uniprot id: E4NHZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

452652:KSE RS32470
gene id: 452652:KSE_RS32470
uniprot id: E4N2E3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS07205
gene id: 452652:KSE_RS07205
uniprot id: E4N7X4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

452652:KSE RS17870
gene id: 452652:KSE_RS17870
uniprot id: E4NDZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

452652:KSE RS37115
gene id: 452652:KSE_RS37115
uniprot id: E4NJW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS28830
gene id: 452652:KSE_RS28830
uniprot id: E4N3W6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

452652:KSE RS15635
gene id: 452652:KSE_RS15635
uniprot id: E4NCP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

452652:KSE RS01915
gene id: 452652:KSE_RS01915
uniprot id: E4N4W5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

452652:KSE RS04930
gene id: 452652:KSE_RS04930
uniprot id: E4N6M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS32915
gene id: 452652:KSE_RS32915
uniprot id: E4N2N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

452652:KSE RS32360
gene id: 452652:KSE_RS32360
uniprot id: E4N2C0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS04845
gene id: 452652:KSE_RS04845
uniprot id: E4N6K4
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

452652:KSE RS20450
gene id: 452652:KSE_RS20450
uniprot id: E4MZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

452652:KSE RS19215
gene id: 452652:KSE_RS19215
uniprot id: E4MZB5
names: Similarity
messages: Belongs to the FemABX family.

452652:KSE RS20910
gene id: 452652:KSE_RS20910
uniprot id: E4MZU3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS15015
gene id: 452652:KSE_RS15015
uniprot id: E4NCC2
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

452652:KSE RS35575
gene id: 452652:KSE_RS35575
uniprot id: E4NJ01
names: Similarity
messages: Belongs to the peptidase M4 family.

452652:KSE RS15605
gene id: 452652:KSE_RS15605
uniprot id: E4NCP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

452652:KSE RS31215
gene id: 452652:KSE_RS31215
uniprot id: E4N1N9
names: Similarity
messages: Belongs to the universal stress protein A family.

452652:KSE RS24235
gene id: 452652:KSE_RS24235
uniprot id: E4NGR1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

452652:KSE RS20195
gene id: 452652:KSE_RS20195
uniprot id: E4NEV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

452652:KSE RS33705
gene id: 452652:KSE_RS33705
uniprot id: E4N342
names: Similarity
messages: Belongs to the peptidase C56 family.

452652:KSE RS34400
gene id: 452652:KSE_RS34400
uniprot id: E4N3I1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS00560
gene id: 452652:KSE_RS00560
uniprot id: E4N438
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS30695
gene id: 452652:KSE_RS30695
uniprot id: E4N1D8
names: Similarity
messages: Belongs to the terpene synthase family.

452652:KSE RS22835
gene id: 452652:KSE_RS22835
uniprot id: E4NFY3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

452652:KSE RS16765
gene id: 452652:KSE_RS16765
uniprot id: E4NDC2
names: Subcellular Location Annotation
messages: Mitochondrion

452652:KSE RS23350
gene id: 452652:KSE_RS23350
uniprot id: E4NG82
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

452652:KSE RS22805
gene id: 452652:KSE_RS22805
uniprot id: E4NFX8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

452652:KSE RS07355
gene id: 452652:KSE_RS07355
uniprot id: E4N804
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS02485
gene id: 452652:KSE_RS02485
uniprot id: E4N585
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

452652:KSE RS27410
gene id: 452652:KSE_RS27410
uniprot id: E4NII4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

452652:KSE RS04950
gene id: 452652:KSE_RS04950
uniprot id: E4N6M4
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

452652:KSE RS28070
gene id: 452652:KSE_RS28070
uniprot id: E4N0C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

452652:KSE RS32605
gene id: 452652:KSE_RS32605
uniprot id: E4N2H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

452652:KSE RS31630
gene id: 452652:KSE_RS31630
uniprot id: E4N1X4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

452652:KSE RS38555
gene id: 452652:KSE_RS38555
uniprot id: E4NDN6
names: Similarity
messages: Belongs to the peptidase C40 family.

452652:KSE RS12770
gene id: 452652:KSE_RS12770
uniprot id: E4NB33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

452652:KSE RS33630
gene id: 452652:KSE_RS33630
uniprot id: E4N327
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

452652:KSE RS06810
gene id: 452652:KSE_RS06810
uniprot id: E4N7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS26015
gene id: 452652:KSE_RS26015
uniprot id: E4NHR4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS16970
gene id: 452652:KSE_RS16970
uniprot id: E4NDG3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS03605
gene id: 452652:KSE_RS03605
uniprot id: E4N5W0
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

452652:KSE RS35830
gene id: 452652:KSE_RS35830
uniprot id: E4NJ52
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS08815
gene id: 452652:KSE_RS08815
uniprot id: E4N8T8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS30660
gene id: 452652:KSE_RS30660
uniprot id: E4N1D1
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS19200
gene id: 452652:KSE_RS19200
uniprot id: E4MZB2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS25250
gene id: 452652:KSE_RS25250
uniprot id: E4NHB2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

452652:KSE RS22280
gene id: 452652:KSE_RS22280
uniprot id: E4NFM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS28135
gene id: 452652:KSE_RS28135
uniprot id: E4N0D3
names: Similarity
messages: Belongs to the asp23 family.

452652:KSE RS06180
gene id: 452652:KSE_RS06180
uniprot id: E4N7C1
names: Similarity
messages: Belongs to the IucA/IucC family.

452652:KSE RS23550
gene id: 452652:KSE_RS23550
uniprot id: E4NGC2
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS05285
gene id: 452652:KSE_RS05285
uniprot id: E4N6U1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

452652:KSE RS11565
gene id: 452652:KSE_RS11565
uniprot id: E4NAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

452652:KSE RS10970
gene id: 452652:KSE_RS10970
uniprot id: E4NA22
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS30950
gene id: 452652:KSE_RS30950
uniprot id: E4N1I6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

452652:KSE RS24775
gene id: 452652:KSE_RS24775
uniprot id: E4NH18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

452652:KSE RS20295
gene id: 452652:KSE_RS20295
uniprot id: E4NEX0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS15495
gene id: 452652:KSE_RS15495
uniprot id: E4NCL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

452652:KSE RS16245
gene id: 452652:KSE_RS16245
uniprot id: E4ND17
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

452652:KSE RS16265
gene id: 452652:KSE_RS16265
uniprot id: E4ND21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS35825
gene id: 452652:KSE_RS35825
uniprot id: E4NJ51
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS08845
gene id: 452652:KSE_RS08845
uniprot id: E4N8U4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

452652:KSE RS18680
gene id: 452652:KSE_RS18680
uniprot id: E4NEF3
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS02845
gene id: 452652:KSE_RS02845
uniprot id: E4N5F8
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS19290
gene id: 452652:KSE_RS19290
uniprot id: E4MZD0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

452652:KSE RS12470
gene id: 452652:KSE_RS12470
uniprot id: E4NAX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

452652:KSE RS35045
gene id: 452652:KSE_RS35045
uniprot id: E4NIP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS24730
gene id: 452652:KSE_RS24730
uniprot id: E4NH09
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS11250
gene id: 452652:KSE_RS11250
uniprot id: E4NA80
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS24440
gene id: 452652:KSE_RS24440
uniprot id: E4NGV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS08940
gene id: 452652:KSE_RS08940
uniprot id: E4N8W2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS12960
gene id: 452652:KSE_RS12960
uniprot id: E4NB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS07005
gene id: 452652:KSE_RS07005
uniprot id: E4N7U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

452652:KSE RS06795
gene id: 452652:KSE_RS06795
uniprot id: E4N7P9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

452652:KSE RS36895
gene id: 452652:KSE_RS36895
uniprot id: E4NJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS07330
gene id: 452652:KSE_RS07330
uniprot id: E4N7Z9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS25145
gene id: 452652:KSE_RS25145
uniprot id: E4NH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS20845
gene id: 452652:KSE_RS20845
uniprot id: E4MZT0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS10900
gene id: 452652:KSE_RS10900
uniprot id: E4NA07
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

452652:KSE RS15570
gene id: 452652:KSE_RS15570
uniprot id: E4NCN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

452652:KSE RS28465
gene id: 452652:KSE_RS28465
uniprot id: E4N3P3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

452652:KSE RS35330
gene id: 452652:KSE_RS35330
uniprot id: E4NIV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

452652:KSE RS23000
gene id: 452652:KSE_RS23000
uniprot id: E4NG14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

452652:KSE RS05400
gene id: 452652:KSE_RS05400
uniprot id: E4N6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

452652:KSE RS28590
gene id: 452652:KSE_RS28590
uniprot id: E4N3R8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

452652:KSE RS11950
gene id: 452652:KSE_RS11950
uniprot id: E4NAM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS22250
gene id: 452652:KSE_RS22250
uniprot id: E4NFL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS09435
gene id: 452652:KSE_RS09435
uniprot id: E4N964
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS12305
gene id: 452652:KSE_RS12305
uniprot id: E4NAU4
names: Similarity
messages: Belongs to the FGGY kinase family.

452652:KSE RS32445
gene id: 452652:KSE_RS32445
uniprot id: E4N2D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS06930
gene id: 452652:KSE_RS06930
uniprot id: E4N7S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

452652:KSE RS01970
gene id: 452652:KSE_RS01970
uniprot id: E4N4X6
names: Similarity
messages: Belongs to the glutamine synthetase family.

452652:KSE RS08540
gene id: 452652:KSE_RS08540
uniprot id: E4N8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS17505
gene id: 452652:KSE_RS17505
uniprot id: E4NDS1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

452652:KSE RS15070
gene id: 452652:KSE_RS15070
uniprot id: E4NCD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS17325
gene id: 452652:KSE_RS17325
uniprot id: E4NDN5
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS16830
gene id: 452652:KSE_RS16830
uniprot id: E4NDD5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

452652:KSE RS32925
gene id: 452652:KSE_RS32925
uniprot id: E4N2N4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

452652:KSE RS07305
gene id: 452652:KSE_RS07305
uniprot id: E4N7Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

452652:KSE RS32435
gene id: 452652:KSE_RS32435
uniprot id: E4N2D6
names: Similarity
messages: Belongs to the thioesterase family.

452652:KSE RS15090
gene id: 452652:KSE_RS15090
uniprot id: E4NCD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

452652:KSE RS19970
gene id: 452652:KSE_RS19970
uniprot id: E4NEQ7
names: Subunit
messages: Homodimer.

452652:KSE RS20790
gene id: 452652:KSE_RS20790
uniprot id: E4MZR9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS24215
gene id: 452652:KSE_RS24215
uniprot id: E4NGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

452652:KSE RS21315
gene id: 452652:KSE_RS21315
uniprot id: E4NF28
names: Similarity
messages: Belongs to the universal stress protein A family.

452652:KSE RS06120
gene id: 452652:KSE_RS06120
uniprot id: E4N7A9
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

452652:KSE RS10885
gene id: 452652:KSE_RS10885
uniprot id: E4NA04
names: Similarity
messages: Belongs to the CobT family.

452652:KSE RS15075
gene id: 452652:KSE_RS15075
uniprot id: E4NCD4
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS23865
gene id: 452652:KSE_RS23865
uniprot id: E4NGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

452652:KSE RS29425
gene id: 452652:KSE_RS29425
uniprot id: E4N0N0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS36555
gene id: 452652:KSE_RS36555
uniprot id: E4NJJ8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS05540
gene id: 452652:KSE_RS05540
uniprot id: E4N6Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

452652:KSE RS15470
gene id: 452652:KSE_RS15470
uniprot id: E4NCL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

452652:KSE RS14940
gene id: 452652:KSE_RS14940
uniprot id: E4NCA7
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

452652:KSE RS18995
gene id: 452652:KSE_RS18995
uniprot id: E4MZ72
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS10705
gene id: 452652:KSE_RS10705
uniprot id: E4N9W8
names: Similarity
messages: Belongs to the peptidase C40 family.

452652:KSE RS20150
gene id: 452652:KSE_RS20150
uniprot id: E4NEU1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS02210
gene id: 452652:KSE_RS02210
uniprot id: E4N524
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

452652:KSE RS24250
gene id: 452652:KSE_RS24250
uniprot id: E4NGR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452652:KSE RS21885
gene id: 452652:KSE_RS21885
uniprot id: E4NFE2
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS14595
gene id: 452652:KSE_RS14595
uniprot id: E4NC39
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

452652:KSE RS36580
gene id: 452652:KSE_RS36580
uniprot id: E4NJK3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

452652:KSE RS21805
gene id: 452652:KSE_RS21805
uniprot id: E4NFC6
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

452652:KSE RS19305
gene id: 452652:KSE_RS19305
uniprot id: E4MZD3
names: Similarity
messages: Belongs to the ParB family.

452652:KSE RS10790
gene id: 452652:KSE_RS10790
uniprot id: E4N9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

452652:KSE RS17615
gene id: 452652:KSE_RS17615
uniprot id: E4NDU4
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

452652:KSE RS13875
gene id: 452652:KSE_RS13875
uniprot id: E4NBP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

452652:KSE RS22305
gene id: 452652:KSE_RS22305
uniprot id: E4NFM9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS24760
gene id: 452652:KSE_RS24760
uniprot id: E4NH15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

452652:KSE RS26035
gene id: 452652:KSE_RS26035
uniprot id: E4NHR8
names: Similarity
messages: Belongs to the CdaR family.

452652:KSE RS08295
gene id: 452652:KSE_RS08295
uniprot id: E4N8I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

452652:KSE RS09055
gene id: 452652:KSE_RS09055
uniprot id: E4N8Y8
names: Similarity
messages: Belongs to the pirin family.

452652:KSE RS33910
gene id: 452652:KSE_RS33910
uniprot id: E4N383
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

452652:KSE RS18655
gene id: 452652:KSE_RS18655
uniprot id: E4NEE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS23630
gene id: 452652:KSE_RS23630
uniprot id: E4NGD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS33225
gene id: 452652:KSE_RS33225
uniprot id: E4N2U5
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

452652:KSE RS00740
gene id: 452652:KSE_RS00740
uniprot id: E4N474
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452652:KSE RS16325
gene id: 452652:KSE_RS16325
uniprot id: E4ND33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

452652:KSE RS32085
gene id: 452652:KSE_RS32085
uniprot id: E4N267
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

452652:KSE RS31835
gene id: 452652:KSE_RS31835
uniprot id: E4N216
names: Similarity
messages: Belongs to the peptidase S66 family.

452652:KSE RS11560
gene id: 452652:KSE_RS11560
uniprot id: E4NAE2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

452652:KSE RS22845
gene id: 452652:KSE_RS22845
uniprot id: E4NFY5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

452652:KSE RS36280
gene id: 452652:KSE_RS36280
uniprot id: E4NJE3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

452652:KSE RS02235
gene id: 452652:KSE_RS02235
uniprot id: E4N529
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS16295
gene id: 452652:KSE_RS16295
uniprot id: E4ND27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS06700
gene id: 452652:KSE_RS06700
uniprot id: E4N7N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

452652:KSE RS26175
gene id: 452652:KSE_RS26175
uniprot id: E4NHU3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS30510
gene id: 452652:KSE_RS30510
uniprot id: E4N1A1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

452652:KSE RS06845
gene id: 452652:KSE_RS06845
uniprot id: E4N7Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

452652:KSE RS25235
gene id: 452652:KSE_RS25235
uniprot id: E4NHA9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

452652:KSE RS14035
gene id: 452652:KSE_RS14035
uniprot id: E4NBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

452652:KSE RS14515
gene id: 452652:KSE_RS14515
uniprot id: E4NC22
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

452652:KSE RS35700
gene id: 452652:KSE_RS35700
uniprot id: E4NJ26
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS28080
gene id: 452652:KSE_RS28080
uniprot id: E4N0C2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS06405
gene id: 452652:KSE_RS06405
uniprot id: E4N7H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS22260
gene id: 452652:KSE_RS22260
uniprot id: E4NFM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS00945
gene id: 452652:KSE_RS00945
uniprot id: E4N4B6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS16435
gene id: 452652:KSE_RS16435
uniprot id: E4ND55
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS09820
gene id: 452652:KSE_RS09820
uniprot id: E4N9E1
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS31900
gene id: 452652:KSE_RS31900
uniprot id: E4N230
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

452652:KSE RS24490
gene id: 452652:KSE_RS24490
uniprot id: E4NGW2
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS26725
gene id: 452652:KSE_RS26725
uniprot id: E4NI50
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS32365
gene id: 452652:KSE_RS32365
uniprot id: E4N2C1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS27990
gene id: 452652:KSE_RS27990
uniprot id: E4N0A4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS22100
gene id: 452652:KSE_RS22100
uniprot id: E4NFI8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

452652:KSE RS22785
gene id: 452652:KSE_RS22785
uniprot id: E4NFX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

452652:KSE RS19205
gene id: 452652:KSE_RS19205
uniprot id: E4MZB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

452652:KSE RS22830
gene id: 452652:KSE_RS22830
uniprot id: E4NFY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS16920
gene id: 452652:KSE_RS16920
uniprot id: E4NDF3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS29305
gene id: 452652:KSE_RS29305
uniprot id: E4N0K6
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

452652:KSE RS03060
gene id: 452652:KSE_RS03060
uniprot id: E4N5K1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

452652:KSE RS23690
gene id: 452652:KSE_RS23690
uniprot id: E4NGF0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS27435
gene id: 452652:KSE_RS27435
uniprot id: E4MZZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

452652:KSE RS25665
gene id: 452652:KSE_RS25665
uniprot id: E4NHJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452652:KSE RS20070
gene id: 452652:KSE_RS20070
uniprot id: E4NES6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS18880
gene id: 452652:KSE_RS18880
uniprot id: E4MZ51
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS13525
gene id: 452652:KSE_RS13525
uniprot id: E4NBI0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

452652:KSE RS27360
gene id: 452652:KSE_RS27360
uniprot id: E4NIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

452652:KSE RS21190
gene id: 452652:KSE_RS21190
uniprot id: E4NF03
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

452652:KSE RS12790
gene id: 452652:KSE_RS12790
uniprot id: E4NB37
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

452652:KSE RS19045
gene id: 452652:KSE_RS19045
uniprot id: E4MZ82
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

452652:KSE RS14475
gene id: 452652:KSE_RS14475
uniprot id: E4NC14
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS12590
gene id: 452652:KSE_RS12590
uniprot id: E4NB01
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

452652:KSE RS26120
gene id: 452652:KSE_RS26120
uniprot id: E4NHT2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS26540
gene id: 452652:KSE_RS26540
uniprot id: E4NI13
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS42390
gene id: 452652:KSE_RS42390
uniprot id: E4N0X5
names: Subcellular Location Annotation
messages: COPI-coated vesicle membrane

452652:KSE RS31010
gene id: 452652:KSE_RS31010
uniprot id: E4N1J8
names: Similarity
messages: Belongs to the UPF0047 family.

452652:KSE RS01135
gene id: 452652:KSE_RS01135
uniprot id: E4N4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS08385
gene id: 452652:KSE_RS08385
uniprot id: E4N8K3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS14845
gene id: 452652:KSE_RS14845
uniprot id: E4NC90
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452652:KSE RS35915
gene id: 452652:KSE_RS35915
uniprot id: E4NJ69
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452652:KSE RS23890
gene id: 452652:KSE_RS23890
uniprot id: E4NGJ0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

452652:KSE RS26480
gene id: 452652:KSE_RS26480
uniprot id: E4NI01
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS11455
gene id: 452652:KSE_RS11455
uniprot id: E4NAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS33555
gene id: 452652:KSE_RS33555
uniprot id: E4N312
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS31430
gene id: 452652:KSE_RS31430
uniprot id: E4N1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

452652:KSE RS35935
gene id: 452652:KSE_RS35935
uniprot id: E4NJ73
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS32040
gene id: 452652:KSE_RS32040
uniprot id: E4N258
names: Similarity
messages: Belongs to the CobH/CbiC family.

452652:KSE RS25065
gene id: 452652:KSE_RS25065
uniprot id: E4NH76
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS35930
gene id: 452652:KSE_RS35930
uniprot id: E4NJ72
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS36030
gene id: 452652:KSE_RS36030
uniprot id: E4NJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

452652:KSE RS05335
gene id: 452652:KSE_RS05335
uniprot id: E4N6V1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

452652:KSE RS23305
gene id: 452652:KSE_RS23305
uniprot id: E4NG74
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452652:KSE RS13265
gene id: 452652:KSE_RS13265
uniprot id: E4NBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS29550
gene id: 452652:KSE_RS29550
uniprot id: E4N0Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

452652:KSE RS12230
gene id: 452652:KSE_RS12230
uniprot id: E4NAT2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

452652:KSE RS18810
gene id: 452652:KSE_RS18810
uniprot id: E4NEI0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

452652:KSE RS10225
gene id: 452652:KSE_RS10225
uniprot id: E4N9M2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS18630
gene id: 452652:KSE_RS18630
uniprot id: E4NEE3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS26330
gene id: 452652:KSE_RS26330
uniprot id: E4NHX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

452652:KSE RS24695
gene id: 452652:KSE_RS24695
uniprot id: E4NH02
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452652:KSE RS05645
gene id: 452652:KSE_RS05645
uniprot id: E4N713
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

452652:KSE RS36850
gene id: 452652:KSE_RS36850
uniprot id: E4NJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

452652:KSE RS17340
gene id: 452652:KSE_RS17340
uniprot id: E4NDN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

452652:KSE RS01545
gene id: 452652:KSE_RS01545
uniprot id: E4N4N9
names: Similarity
messages: Belongs to the EfeM/EfeO family.

452652:KSE RS31185
gene id: 452652:KSE_RS31185
uniprot id: E4N1N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS28580
gene id: 452652:KSE_RS28580
uniprot id: E4N3R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS24725
gene id: 452652:KSE_RS24725
uniprot id: E4NH08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS09285
gene id: 452652:KSE_RS09285
uniprot id: E4N934
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS09910
gene id: 452652:KSE_RS09910
uniprot id: E4N9F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

452652:KSE RS14230
gene id: 452652:KSE_RS14230
uniprot id: E4NBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

452652:KSE RS06615
gene id: 452652:KSE_RS06615
uniprot id: E4N7L3
names: Similarity
messages: Belongs to the pirin family.

452652:KSE RS32955
gene id: 452652:KSE_RS32955
uniprot id: E4N2P0
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

452652:KSE RS15060
gene id: 452652:KSE_RS15060
uniprot id: E4NCD1
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

452652:KSE RS14625
gene id: 452652:KSE_RS14625
uniprot id: E4NC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

452652:KSE RS08715
gene id: 452652:KSE_RS08715
uniprot id: E4N8R8
names: Similarity
messages: Belongs to the Fur family.

452652:KSE RS28290
gene id: 452652:KSE_RS28290
uniprot id: E4N3L2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS06775
gene id: 452652:KSE_RS06775
uniprot id: E4N7P5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

452652:KSE RS27925
gene id: 452652:KSE_RS27925
uniprot id: E4N091
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

452652:KSE RS17685
gene id: 452652:KSE_RS17685
uniprot id: E4NDV8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

452652:KSE RS11515
gene id: 452652:KSE_RS11515
uniprot id: E4NAD3
names: Similarity
messages: Belongs to the glutamine synthetase family.

452652:KSE RS25195
gene id: 452652:KSE_RS25195
uniprot id: E4NHA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS14325
gene id: 452652:KSE_RS14325
uniprot id: E4NBY7
names: Similarity
messages: Belongs to the NodU/CmcH family.

452652:KSE RS17710
gene id: 452652:KSE_RS17710
uniprot id: E4NDW3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS17660
gene id: 452652:KSE_RS17660
uniprot id: E4NDV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

452652:KSE RS25960
gene id: 452652:KSE_RS25960
uniprot id: E4NHQ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

452652:KSE RS11645
gene id: 452652:KSE_RS11645
uniprot id: E4NAF9
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS24755
gene id: 452652:KSE_RS24755
uniprot id: E4NH14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

452652:KSE RS18640
gene id: 452652:KSE_RS18640
uniprot id: E4NEE5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452652:KSE RS09765
gene id: 452652:KSE_RS09765
uniprot id: E4N9C9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS22035
gene id: 452652:KSE_RS22035
uniprot id: E4NFH5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

452652:KSE RS14755
gene id: 452652:KSE_RS14755
uniprot id: E4NC72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

452652:KSE RS26840
gene id: 452652:KSE_RS26840
uniprot id: E4NI73
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

452652:KSE RS08850
gene id: 452652:KSE_RS08850
uniprot id: E4N8U5
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS30290
gene id: 452652:KSE_RS30290
uniprot id: E4N155
names: Similarity
messages: Belongs to the UPF0225 family.

452652:KSE RS31180
gene id: 452652:KSE_RS31180
uniprot id: E4N1N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS25290
gene id: 452652:KSE_RS25290
uniprot id: E4NHC1
names: Similarity
messages: Belongs to the peptidase S8 family.

452652:KSE RS14445
gene id: 452652:KSE_RS14445
uniprot id: E4NC09
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS07255
gene id: 452652:KSE_RS07255
uniprot id: E4N7Y4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

452652:KSE RS32840
gene id: 452652:KSE_RS32840
uniprot id: E4N2L7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452652:KSE RS05465
gene id: 452652:KSE_RS05465
uniprot id: E4N6X7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS24985
gene id: 452652:KSE_RS24985
uniprot id: E4NH60
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

452652:KSE RS33015
gene id: 452652:KSE_RS33015
uniprot id: E4N2Q3
names: Similarity
messages: Belongs to the DapA family.

452652:KSE RS15630
gene id: 452652:KSE_RS15630
uniprot id: E4NCP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

452652:KSE RS22290
gene id: 452652:KSE_RS22290
uniprot id: E4NFM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS37510
gene id: 452652:KSE_RS37510
uniprot id: E4N408
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

452652:KSE RS23660
gene id: 452652:KSE_RS23660
uniprot id: E4NGE4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

452652:KSE RS04055
gene id: 452652:KSE_RS04055
uniprot id: E4N650
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS18040
gene id: 452652:KSE_RS18040
uniprot id: E4NE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

452652:KSE RS22770
gene id: 452652:KSE_RS22770
uniprot id: E4NFX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

452652:KSE RS06820
gene id: 452652:KSE_RS06820
uniprot id: E4N7Q4
names: Similarity
messages: Belongs to the FPG family.

452652:KSE RS28220
gene id: 452652:KSE_RS28220
uniprot id: E4N3J7
names: Similarity
messages: Belongs to the peptidase U62 family.

452652:KSE RS06975
gene id: 452652:KSE_RS06975
uniprot id: E4N7T5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

452652:KSE RS29380
gene id: 452652:KSE_RS29380
uniprot id: E4N0M1
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

452652:KSE RS10050
gene id: 452652:KSE_RS10050
uniprot id: E4N9I6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS13670
gene id: 452652:KSE_RS13670
uniprot id: E4NBK7
names: Similarity
messages: Belongs to the YciI family.

452652:KSE RS22340
gene id: 452652:KSE_RS22340
uniprot id: E4NFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

452652:KSE RS23750
gene id: 452652:KSE_RS23750
uniprot id: E4NGG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

452652:KSE RS22940
gene id: 452652:KSE_RS22940
uniprot id: E4NG02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

452652:KSE RS38735
gene id: 452652:KSE_RS38735
uniprot id: E4NFR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

452652:KSE RS04405
gene id: 452652:KSE_RS04405
uniprot id: E4N6B9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS20705
gene id: 452652:KSE_RS20705
uniprot id: E4MZQ1
names: Similarity
messages: Belongs to the NDK family.

452652:KSE RS02590
gene id: 452652:KSE_RS02590
uniprot id: E4N5A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

452652:KSE RS11795
gene id: 452652:KSE_RS11795
uniprot id: E4NAJ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

452652:KSE RS07560
gene id: 452652:KSE_RS07560
uniprot id: E4N842
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS06730
gene id: 452652:KSE_RS06730
uniprot id: E4N7N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

452652:KSE RS31365
gene id: 452652:KSE_RS31365
uniprot id: E4N1S0
names: Similarity
messages: Belongs to the allantoicase family.

452652:KSE RS06675
gene id: 452652:KSE_RS06675
uniprot id: E4N7M5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

452652:KSE RS30230
gene id: 452652:KSE_RS30230
uniprot id: E4N142
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

452652:KSE RS35900
gene id: 452652:KSE_RS35900
uniprot id: E4NJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

452652:KSE RS34340
gene id: 452652:KSE_RS34340
uniprot id: E4N3G9
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

452652:KSE RS17065
gene id: 452652:KSE_RS17065
uniprot id: E4NDI1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

452652:KSE RS30835
gene id: 452652:KSE_RS30835
uniprot id: E4N1G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

452652:KSE RS22585
gene id: 452652:KSE_RS22585
uniprot id: E4NFT3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

452652:KSE RS12820
gene id: 452652:KSE_RS12820
uniprot id: E4NB43
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS27830
gene id: 452652:KSE_RS27830
uniprot id: E4N072
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS28250
gene id: 452652:KSE_RS28250
uniprot id: E4N3K3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15370
gene id: 452652:KSE_RS15370
uniprot id: E4NCJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

452652:KSE RS07965
gene id: 452652:KSE_RS07965
uniprot id: E4N8C1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

452652:KSE RS11555
gene id: 452652:KSE_RS11555
uniprot id: E4NAE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

452652:KSE RS28495
gene id: 452652:KSE_RS28495
uniprot id: E4N3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

452652:KSE RS01390
gene id: 452652:KSE_RS01390
uniprot id: E4N4K6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452652:KSE RS15840
gene id: 452652:KSE_RS15840
uniprot id: E4NCT7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS20185
gene id: 452652:KSE_RS20185
uniprot id: E4NEU8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

452652:KSE RS07675
gene id: 452652:KSE_RS07675
uniprot id: E4N865
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

452652:KSE RS30275
gene id: 452652:KSE_RS30275
uniprot id: E4N152
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

452652:KSE RS31420
gene id: 452652:KSE_RS31420
uniprot id: E4N1T1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

452652:KSE RS25500
gene id: 452652:KSE_RS25500
uniprot id: E4NHG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

452652:KSE RS16430
gene id: 452652:KSE_RS16430
uniprot id: E4ND54
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS29230
gene id: 452652:KSE_RS29230
uniprot id: E4N0J1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

452652:KSE RS04035
gene id: 452652:KSE_RS04035
uniprot id: E4N646
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS11460
gene id: 452652:KSE_RS11460
uniprot id: E4NAC2
names: Similarity
messages: Belongs to the peptidase M4 family.

452652:KSE RS20935
gene id: 452652:KSE_RS20935
uniprot id: E4MZU8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

452652:KSE RS03040
gene id: 452652:KSE_RS03040
uniprot id: E4N5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS20470
gene id: 452652:KSE_RS20470
uniprot id: E4MZK9
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

452652:KSE RS12575
gene id: 452652:KSE_RS12575
uniprot id: E4NAZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

452652:KSE RS07195
gene id: 452652:KSE_RS07195
uniprot id: E4N7X2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

452652:KSE RS10075
gene id: 452652:KSE_RS10075
uniprot id: E4N9J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

452652:KSE RS15550
gene id: 452652:KSE_RS15550
uniprot id: E4NCN0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

452652:KSE RS00275
gene id: 452652:KSE_RS00275
uniprot id: E4MZ16
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS09855
gene id: 452652:KSE_RS09855
uniprot id: E4N9E8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

452652:KSE RS21005
gene id: 452652:KSE_RS21005
uniprot id: E4MZW2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS14685
gene id: 452652:KSE_RS14685
uniprot id: E4NC57
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

452652:KSE RS24805
gene id: 452652:KSE_RS24805
uniprot id: E4NH24
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

452652:KSE RS15865
gene id: 452652:KSE_RS15865
uniprot id: E4NCU2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS32210
gene id: 452652:KSE_RS32210
uniprot id: E4N292
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

452652:KSE RS24570
gene id: 452652:KSE_RS24570
uniprot id: E4NGX8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

452652:KSE RS18475
gene id: 452652:KSE_RS18475
uniprot id: E4NEB4
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS21780
gene id: 452652:KSE_RS21780
uniprot id: E4NFC0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS07550
gene id: 452652:KSE_RS07550
uniprot id: E4N840
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452652:KSE RS06170
gene id: 452652:KSE_RS06170
uniprot id: E4N7B9
names: Similarity
messages: Belongs to the IucA/IucC family.

452652:KSE RS24950
gene id: 452652:KSE_RS24950
uniprot id: E4NH53
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

452652:KSE RS17815
gene id: 452652:KSE_RS17815
uniprot id: E4NDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

452652:KSE RS37625
gene id: 452652:KSE_RS37625
uniprot id: E4MZ23
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

452652:KSE RS25270
gene id: 452652:KSE_RS25270
uniprot id: E4NHB6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

452652:KSE RS16310
gene id: 452652:KSE_RS16310
uniprot id: E4ND30
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

452652:KSE RS08820
gene id: 452652:KSE_RS08820
uniprot id: E4N8T9
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

452652:KSE RS14190
gene id: 452652:KSE_RS14190
uniprot id: E4NBV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS23545
gene id: 452652:KSE_RS23545
uniprot id: E4NGC1
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

452652:KSE RS04095
gene id: 452652:KSE_RS04095
uniprot id: E4N657
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS25015
gene id: 452652:KSE_RS25015
uniprot id: E4NH66
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

452652:KSE RS28820
gene id: 452652:KSE_RS28820
uniprot id: E4N3W4
names: Similarity
messages: Belongs to the CdaR family.

452652:KSE RS32950
gene id: 452652:KSE_RS32950
uniprot id: E4N2N9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

452652:KSE RS18820
gene id: 452652:KSE_RS18820
uniprot id: E4NEI2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

452652:KSE RS30625
gene id: 452652:KSE_RS30625
uniprot id: E4N1C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS22070
gene id: 452652:KSE_RS22070
uniprot id: E4NFI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

452652:KSE RS06080
gene id: 452652:KSE_RS06080
uniprot id: E4N7A1
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

452652:KSE RS13885
gene id: 452652:KSE_RS13885
uniprot id: E4NBP9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS16385
gene id: 452652:KSE_RS16385
uniprot id: E4ND45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS21690
gene id: 452652:KSE_RS21690
uniprot id: E4NFA2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

452652:KSE RS26010
gene id: 452652:KSE_RS26010
uniprot id: E4NHR3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452652:KSE RS28540
gene id: 452652:KSE_RS28540
uniprot id: E4N3Q8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

452652:KSE RS45435
gene id: 452652:KSE_RS45435
uniprot id: E4NJV8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

452652:KSE RS01475
gene id: 452652:KSE_RS01475
uniprot id: E4N4M5
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS26040
gene id: 452652:KSE_RS26040
uniprot id: E4NHR9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452652:KSE RS07660
gene id: 452652:KSE_RS07660
uniprot id: E4N862
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS26550
gene id: 452652:KSE_RS26550
uniprot id: E4NI15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

452652:KSE RS14955
gene id: 452652:KSE_RS14955
uniprot id: E4NCB0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS16015
gene id: 452652:KSE_RS16015
uniprot id: E4NCX0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

452652:KSE RS19055
gene id: 452652:KSE_RS19055
uniprot id: E4MZ84
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS37560
gene id: 452652:KSE_RS37560
uniprot id: E4MZ36
names: Similarity
messages: Belongs to the phosphohexose mutase family.

452652:KSE RS30930
gene id: 452652:KSE_RS30930
uniprot id: E4N1I2
names: Similarity
messages: Belongs to the group II decarboxylase family.

452652:KSE RS26355
gene id: 452652:KSE_RS26355
uniprot id: E4NHX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

452652:KSE RS28440
gene id: 452652:KSE_RS28440
uniprot id: E4N3N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

452652:KSE RS21930
gene id: 452652:KSE_RS21930
uniprot id: E4NFF2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

452652:KSE RS03600
gene id: 452652:KSE_RS03600
uniprot id: E4N5V9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

452652:KSE RS08610
gene id: 452652:KSE_RS08610
uniprot id: E4N8P8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS25305
gene id: 452652:KSE_RS25305
uniprot id: E4NHC4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS25000
gene id: 452652:KSE_RS25000
uniprot id: E4NH63
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

452652:KSE RS14080
gene id: 452652:KSE_RS14080
uniprot id: E4NBT9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS15080
gene id: 452652:KSE_RS15080
uniprot id: E4NCD5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

452652:KSE RS02850
gene id: 452652:KSE_RS02850
uniprot id: E4N5F9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS29100
gene id: 452652:KSE_RS29100
uniprot id: E4N0G6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

452652:KSE RS18240
gene id: 452652:KSE_RS18240
uniprot id: E4NE69
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS36490
gene id: 452652:KSE_RS36490
uniprot id: E4NJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

452652:KSE RS24380
gene id: 452652:KSE_RS24380
uniprot id: E4NGU0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

452652:KSE RS04925
gene id: 452652:KSE_RS04925
uniprot id: E4N6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS17875
gene id: 452652:KSE_RS17875
uniprot id: E4NDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

452652:KSE RS04665
gene id: 452652:KSE_RS04665
uniprot id: E4N6G8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS06585
gene id: 452652:KSE_RS06585
uniprot id: E4N7K7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

452652:KSE RS22590
gene id: 452652:KSE_RS22590
uniprot id: E4NFT4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

452652:KSE RS19330
gene id: 452652:KSE_RS19330
uniprot id: E4MZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

452652:KSE RS07115
gene id: 452652:KSE_RS07115
uniprot id: E4N7W1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS30245
gene id: 452652:KSE_RS30245
uniprot id: E4N145
names: Similarity
messages: Belongs to the peptidase M1 family.

452652:KSE RS23765
gene id: 452652:KSE_RS23765
uniprot id: E4NGG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS14910
gene id: 452652:KSE_RS14910
uniprot id: E4NCA2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS21895
gene id: 452652:KSE_RS21895
uniprot id: E4NFE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

452652:KSE RS14830
gene id: 452652:KSE_RS14830
uniprot id: E4NC87
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS12655
gene id: 452652:KSE_RS12655
uniprot id: E4NB14
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

452652:KSE RS32990
gene id: 452652:KSE_RS32990
uniprot id: E4N2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

452652:KSE RS19350
gene id: 452652:KSE_RS19350
uniprot id: E4MZE3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

452652:KSE RS18885
gene id: 452652:KSE_RS18885
uniprot id: E4MZ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

452652:KSE RS27395
gene id: 452652:KSE_RS27395
uniprot id: E4NII1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

452652:KSE RS13575
gene id: 452652:KSE_RS13575
uniprot id: E4NBJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

452652:KSE RS08445
gene id: 452652:KSE_RS08445
uniprot id: E4N8L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS18675
gene id: 452652:KSE_RS18675
uniprot id: E4NEF2
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

452652:KSE RS03180
gene id: 452652:KSE_RS03180
uniprot id: E4N5M4
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS31320
gene id: 452652:KSE_RS31320
uniprot id: E4N1R1
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

452652:KSE RS36765
gene id: 452652:KSE_RS36765
uniprot id: E4NJP0
names: Similarity
messages: Belongs to the CFA/CMAS family.

452652:KSE RS26770
gene id: 452652:KSE_RS26770
uniprot id: E4NI59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

452652:KSE RS23280
gene id: 452652:KSE_RS23280
uniprot id: E4NG69
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS22315
gene id: 452652:KSE_RS22315
uniprot id: E4NFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS10065
gene id: 452652:KSE_RS10065
uniprot id: E4N9I9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

452652:KSE RS30205
gene id: 452652:KSE_RS30205
uniprot id: E4N137
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

452652:KSE RS25520
gene id: 452652:KSE_RS25520
uniprot id: E4NHG5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

452652:KSE RS07415
gene id: 452652:KSE_RS07415
uniprot id: E4N816
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS08785
gene id: 452652:KSE_RS08785
uniprot id: E4N8T2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

452652:KSE RS27945
gene id: 452652:KSE_RS27945
uniprot id: E4N095
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

452652:KSE RS28130
gene id: 452652:KSE_RS28130
uniprot id: E4N0D2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

452652:KSE RS04580
gene id: 452652:KSE_RS04580
uniprot id: E4N6F1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

452652:KSE RS26820
gene id: 452652:KSE_RS26820
uniprot id: E4NI69
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS15815
gene id: 452652:KSE_RS15815
uniprot id: E4NCT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

452652:KSE RS09730
gene id: 452652:KSE_RS09730
uniprot id: E4N9C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS05800
gene id: 452652:KSE_RS05800
uniprot id: E4N744
names: Similarity
messages: Belongs to the CdaR family.

452652:KSE RS17050
gene id: 452652:KSE_RS17050
uniprot id: E4NDH8
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS03755
gene id: 452652:KSE_RS03755
uniprot id: E4N5Z0
names: Subcellular Location Annotation
messages: Cell membrane

452652:KSE RS12450
gene id: 452652:KSE_RS12450
uniprot id: E4NAX2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

452652:KSE RS00460
gene id: 452652:KSE_RS00460
uniprot id: E4N415
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

452652:KSE RS14010
gene id: 452652:KSE_RS14010
uniprot id: E4NBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

452652:KSE RS14705
gene id: 452652:KSE_RS14705
uniprot id: E4NC61
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS05955
gene id: 452652:KSE_RS05955
uniprot id: E4N777
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

452652:KSE RS17135
gene id: 452652:KSE_RS17135
uniprot id: E4NDJ5
names: Similarity
messages: Belongs to the peptidase S33 family.

452652:KSE RS06725
gene id: 452652:KSE_RS06725
uniprot id: E4N7N5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

452652:KSE RS18780
gene id: 452652:KSE_RS18780
uniprot id: E4NEH4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS04685
gene id: 452652:KSE_RS04685
uniprot id: E4N6H2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

452652:KSE RS21545
gene id: 452652:KSE_RS21545
uniprot id: E4NF73
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

452652:KSE RS15395
gene id: 452652:KSE_RS15395
uniprot id: E4NCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

452652:KSE RS01495
gene id: 452652:KSE_RS01495
uniprot id: E4N4M9
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS28240
gene id: 452652:KSE_RS28240
uniprot id: E4N3K1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

452652:KSE RS31315
gene id: 452652:KSE_RS31315
uniprot id: E4N1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

452652:KSE RS05665
gene id: 452652:KSE_RS05665
uniprot id: E4N717
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

452652:KSE RS08015
gene id: 452652:KSE_RS08015
uniprot id: E4N8D1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

452652:KSE RS07260
gene id: 452652:KSE_RS07260
uniprot id: E4N7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

452652:KSE RS25180
gene id: 452652:KSE_RS25180
uniprot id: E4NH99
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

452652:KSE RS33290
gene id: 452652:KSE_RS33290
uniprot id: E4N2V8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

452652:KSE RS11915
gene id: 452652:KSE_RS11915
uniprot id: E4NAL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

452652:KSE RS30585
gene id: 452652:KSE_RS30585
uniprot id: E4N1B6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

452652:KSE RS34455
gene id: 452652:KSE_RS34455
uniprot id: E4N3J1
names: Similarity
messages: Belongs to the EccD/Snm4 family.

452652:KSE RS22890
gene id: 452652:KSE_RS22890
uniprot id: E4NFZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

452652:KSE RS20125
gene id: 452652:KSE_RS20125
uniprot id: E4NET6
names: Similarity
messages: Belongs to the XFP family.

452652:KSE RS29665
gene id: 452652:KSE_RS29665
uniprot id: E4N0T0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

452652:KSE RS25285
gene id: 452652:KSE_RS25285
uniprot id: E4NHB9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

452652:KSE RS24000
gene id: 452652:KSE_RS24000
uniprot id: E4NGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

452652:KSE RS19270
gene id: 452652:KSE_RS19270
uniprot id: E4MZC6
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS19640
gene id: 452652:KSE_RS19640
uniprot id: E4NEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

452652:KSE RS11365
gene id: 452652:KSE_RS11365
uniprot id: E4NAA3
names: Similarity
messages: Belongs to the ArsC family.

452652:KSE RS30845
gene id: 452652:KSE_RS30845
uniprot id: E4N1G6
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS04970
gene id: 452652:KSE_RS04970
uniprot id: E4N6M8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS36975
gene id: 452652:KSE_RS36975
uniprot id: E4NJT2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS18125
gene id: 452652:KSE_RS18125
uniprot id: E4NE46
names: Similarity
messages: Belongs to the YoeB family.

452652:KSE RS26320
gene id: 452652:KSE_RS26320
uniprot id: E4NHX2
names: Similarity
messages: Belongs to the EccD/Snm4 family.

452652:KSE RS06255
gene id: 452652:KSE_RS06255
uniprot id: E4N7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS12975
gene id: 452652:KSE_RS12975
uniprot id: E4NB73
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

452652:KSE RS21850
gene id: 452652:KSE_RS21850
uniprot id: E4NFD5
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS18935
gene id: 452652:KSE_RS18935
uniprot id: E4MZ62
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

452652:KSE RS26610
gene id: 452652:KSE_RS26610
uniprot id: E4NI27
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

452652:KSE RS07015
gene id: 452652:KSE_RS07015
uniprot id: E4N7U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

452652:KSE RS27760
gene id: 452652:KSE_RS27760
uniprot id: E4N056
names: Similarity
messages: Belongs to the glutamine synthetase family.

452652:KSE RS37215
gene id: 452652:KSE_RS37215
uniprot id: E4NJY0
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS18355
gene id: 452652:KSE_RS18355
uniprot id: E4NE93
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

452652:KSE RS23205
gene id: 452652:KSE_RS23205
uniprot id: E4NG55
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

452652:KSE RS27450
gene id: 452652:KSE_RS27450
uniprot id: E4MZZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS29370
gene id: 452652:KSE_RS29370
uniprot id: E4N0L9
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS35920
gene id: 452652:KSE_RS35920
uniprot id: E4NJ70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

452652:KSE RS01140
gene id: 452652:KSE_RS01140
uniprot id: E4N4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS04980
gene id: 452652:KSE_RS04980
uniprot id: E4N6N0
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

452652:KSE RS37490
gene id: 452652:KSE_RS37490
uniprot id: E4N412
names: Similarity
messages: Belongs to the TPP enzyme family.

452652:KSE RS02860
gene id: 452652:KSE_RS02860
uniprot id: E4N5G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS32290
gene id: 452652:KSE_RS32290
uniprot id: E4N2A8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS27455
gene id: 452652:KSE_RS27455
uniprot id: E4MZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

452652:KSE RS00975
gene id: 452652:KSE_RS00975
uniprot id: E4N4C2
names: Similarity
messages: Belongs to the peptidase S33 family.

452652:KSE RS01410
gene id: 452652:KSE_RS01410
uniprot id: E4N4L0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

452652:KSE RS30085
gene id: 452652:KSE_RS30085
uniprot id: E4N114
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

452652:KSE RS03460
gene id: 452652:KSE_RS03460
uniprot id: E4N5T1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

452652:KSE RS12845
gene id: 452652:KSE_RS12845
uniprot id: E4NB48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

452652:KSE RS20445
gene id: 452652:KSE_RS20445
uniprot id: E4MZK4
names: Similarity
messages: Belongs to the LOR family.

452652:KSE RS28965
gene id: 452652:KSE_RS28965
uniprot id: E4N3Z4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

452652:KSE RS08530
gene id: 452652:KSE_RS08530
uniprot id: E4N8N2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

452652:KSE RS23485
gene id: 452652:KSE_RS23485
uniprot id: E4NGB0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS16290
gene id: 452652:KSE_RS16290
uniprot id: E4ND26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

452652:KSE RS32945
gene id: 452652:KSE_RS32945
uniprot id: E4N2N8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

452652:KSE RS31280
gene id: 452652:KSE_RS31280
uniprot id: E4N1Q3
names: Similarity
messages: Belongs to the malate synthase family.

452652:KSE RS05745
gene id: 452652:KSE_RS05745
uniprot id: E4N733
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

452652:KSE RS07290
gene id: 452652:KSE_RS07290
uniprot id: E4N7Z1
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

452652:KSE RS34965
gene id: 452652:KSE_RS34965
uniprot id: E4NIM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS18575
gene id: 452652:KSE_RS18575
uniprot id: E4NED2
names: Similarity
messages: Belongs to the peptidase M24B family.

452652:KSE RS29930
gene id: 452652:KSE_RS29930
uniprot id: E4N0Y4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS08550
gene id: 452652:KSE_RS08550
uniprot id: E4N8N6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

452652:KSE RS14235
gene id: 452652:KSE_RS14235
uniprot id: E4NBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

452652:KSE RS33135
gene id: 452652:KSE_RS33135
uniprot id: E4N2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

452652:KSE RS05925
gene id: 452652:KSE_RS05925
uniprot id: E4N769
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

452652:KSE RS12485
gene id: 452652:KSE_RS12485
uniprot id: E4NAX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

452652:KSE RS25625
gene id: 452652:KSE_RS25625
uniprot id: E4NHI6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

452652:KSE RS09145
gene id: 452652:KSE_RS09145
uniprot id: E4N906
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

452652:KSE RS03765
gene id: 452652:KSE_RS03765
uniprot id: E4N5Z2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

452652:KSE RS07665
gene id: 452652:KSE_RS07665
uniprot id: E4N863
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

452652:KSE RS22210
gene id: 452652:KSE_RS22210
uniprot id: E4NFL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

452652:KSE RS35660
gene id: 452652:KSE_RS35660
uniprot id: E4NJ18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

452652:KSE RS13505
gene id: 452652:KSE_RS13505
uniprot id: E4NBH5
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS03225
gene id: 452652:KSE_RS03225
uniprot id: E4N5N3
names: Similarity
messages: Belongs to the peptidase M4 family.

452652:KSE RS03625
gene id: 452652:KSE_RS03625
uniprot id: E4N5W4
names: Similarity
messages: Belongs to the AHA1 family.

452652:KSE RS20220
gene id: 452652:KSE_RS20220
uniprot id: E4NEV5
names: Similarity
messages: Belongs to the SCO1/2 family.

452652:KSE RS30960
gene id: 452652:KSE_RS30960
uniprot id: E4N1I8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

452652:KSE RS22320
gene id: 452652:KSE_RS22320
uniprot id: E4NFN2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

452652:KSE RS13455
gene id: 452652:KSE_RS13455
uniprot id: E4NBG5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

452652:KSE RS35480
gene id: 452652:KSE_RS35480
uniprot id: E4NIY3
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS18145
gene id: 452652:KSE_RS18145
uniprot id: E4NE50
names: Subcellular Location Annotation
messages: Cytoplasm

452652:KSE RS26525
gene id: 452652:KSE_RS26525
uniprot id: E4NI10
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

452652:KSE RS26425
gene id: 452652:KSE_RS26425
uniprot id: E4NHZ0
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

452652:KSE RS30925
gene id: 452652:KSE_RS30925
uniprot id: E4N1I1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

452652:KSE RS17705
gene id: 452652:KSE_RS17705
uniprot id: E4NDW2
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS25580
gene id: 452652:KSE_RS25580
uniprot id: E4NHH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

452652:KSE RS26125
gene id: 452652:KSE_RS26125
uniprot id: E4NHT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

452652:KSE RS14140
gene id: 452652:KSE_RS14140
uniprot id: E4NBV0
names: Similarity
messages: Belongs to the peptidase S8 family.

452652:KSE RS19830
gene id: 452652:KSE_RS19830
uniprot id: E4NEM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

452652:KSE RS01725
gene id: 452652:KSE_RS01725
uniprot id: E4N4S6
names: Similarity
messages: Belongs to the cytochrome P450 family.

452652:KSE RS39545
gene id: 452652:KSE_RS39545
uniprot id: E4N489
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS08775
gene id: 452652:KSE_RS08775
uniprot id: E4N8T0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS02825
gene id: 452652:KSE_RS02825
uniprot id: E4N5F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

452652:KSE RS22870
gene id: 452652:KSE_RS22870
uniprot id: E4NFZ0
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS35160
gene id: 452652:KSE_RS35160
uniprot id: E4NIR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

452652:KSE RS19355
gene id: 452652:KSE_RS19355
uniprot id: E4MZE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

452652:KSE RS06895
gene id: 452652:KSE_RS06895
uniprot id: E4N7R9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

452652:KSE RS07390
gene id: 452652:KSE_RS07390
uniprot id: E4N811
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

452652:KSE RS35890
gene id: 452652:KSE_RS35890
uniprot id: E4NJ64
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS26945
gene id: 452652:KSE_RS26945
uniprot id: E4NI91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

452652:KSE RS03715
gene id: 452652:KSE_RS03715
uniprot id: E4N5Y2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

452652:KSE RS12015
gene id: 452652:KSE_RS12015
uniprot id: E4NAN8
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS17780
gene id: 452652:KSE_RS17780
uniprot id: E4NDX7
names: Subcellular Location Annotation
messages: Membrane

452652:KSE RS06620
gene id: 452652:KSE_RS06620
uniprot id: E4N7L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.