446469:SKED RS07535
gene id: 446469:SKED_RS07535
uniprot id: D1BFW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

446469:SKED RS12125
gene id: 446469:SKED_RS12125
uniprot id: D1BJX4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

446469:SKED RS03580
gene id: 446469:SKED_RS03580
uniprot id: D1BBC4
names: Similarity
messages: Belongs to the peptidase S1C family.

446469:SKED RS00725
gene id: 446469:SKED_RS00725
uniprot id: D1BIT2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446469:SKED RS02780
gene id: 446469:SKED_RS02780
uniprot id: D1BAI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

446469:SKED RS00400
gene id: 446469:SKED_RS00400
uniprot id: D1BI81
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS15180
gene id: 446469:SKED_RS15180
uniprot id: D1BCK2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS16335
gene id: 446469:SKED_RS16335
uniprot id: D1BE00
names: Similarity
messages: Belongs to the peptidase M20A family.

446469:SKED RS04965
gene id: 446469:SKED_RS04965
uniprot id: D1BCW6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS01050
gene id: 446469:SKED_RS01050
uniprot id: D1BIZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

446469:SKED RS00390
gene id: 446469:SKED_RS00390
uniprot id: D1BI79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS04170
gene id: 446469:SKED_RS04170
uniprot id: D1BC26
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

446469:SKED RS10760
gene id: 446469:SKED_RS10760
uniprot id: D1BID4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

446469:SKED RS09090
gene id: 446469:SKED_RS09090
uniprot id: D1BH59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

446469:SKED RS10755
gene id: 446469:SKED_RS10755
uniprot id: D1BID3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

446469:SKED RS14085
gene id: 446469:SKED_RS14085
uniprot id: D1BBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

446469:SKED RS00020
gene id: 446469:SKED_RS00020
uniprot id: D1BI09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

446469:SKED RS14590
gene id: 446469:SKED_RS14590
uniprot id: D1BBV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

446469:SKED RS13000
gene id: 446469:SKED_RS13000
uniprot id: D1BKS6
names: Similarity
messages: Belongs to the HSP15 family.

446469:SKED RS17830
gene id: 446469:SKED_RS17830
uniprot id: D1BFL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

446469:SKED RS07275
gene id: 446469:SKED_RS07275
uniprot id: D1BFQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

446469:SKED RS05070
gene id: 446469:SKED_RS05070
uniprot id: D1BCY8
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

446469:SKED RS02515
gene id: 446469:SKED_RS02515
uniprot id: D1BAC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

446469:SKED RS10645
gene id: 446469:SKED_RS10645
uniprot id: D1BIB2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

446469:SKED RS14560
gene id: 446469:SKED_RS14560
uniprot id: D1BBU7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

446469:SKED RS10865
gene id: 446469:SKED_RS10865
uniprot id: D1BIF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS16385
gene id: 446469:SKED_RS16385
uniprot id: D1BE10
names: Similarity
messages: Belongs to the GSP E family.

446469:SKED RS11165
gene id: 446469:SKED_RS11165
uniprot id: D1BIL4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

446469:SKED RS17125
gene id: 446469:SKED_RS17125
uniprot id: D1BET9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

446469:SKED RS06920
gene id: 446469:SKED_RS06920
uniprot id: D1BF52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

446469:SKED RS07520
gene id: 446469:SKED_RS07520
uniprot id: D1BFW1
names: Similarity
messages: Belongs to the glutamine synthetase family.

446469:SKED RS03350
gene id: 446469:SKED_RS03350
uniprot id: D1BB81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

446469:SKED RS13600
gene id: 446469:SKED_RS13600
uniprot id: D1BAX4
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS08710
gene id: 446469:SKED_RS08710
uniprot id: D1BGY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

446469:SKED RS14935
gene id: 446469:SKED_RS14935
uniprot id: D1BCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

446469:SKED RS06620
gene id: 446469:SKED_RS06620
uniprot id: D1BEZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

446469:SKED RS14810
gene id: 446469:SKED_RS14810
uniprot id: D1BCD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

446469:SKED RS01260
gene id: 446469:SKED_RS01260
uniprot id: D1BJH0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS03600
gene id: 446469:SKED_RS03600
uniprot id: D1BBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446469:SKED RS12480
gene id: 446469:SKED_RS12480
uniprot id: D1BK37
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

446469:SKED RS15770
gene id: 446469:SKED_RS15770
uniprot id: D1BDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

446469:SKED RS11335
gene id: 446469:SKED_RS11335
uniprot id: D1BJ31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446469:SKED RS14585
gene id: 446469:SKED_RS14585
uniprot id: D1BBV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

446469:SKED RS08150
gene id: 446469:SKED_RS08150
uniprot id: D1BGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

446469:SKED RS03235
gene id: 446469:SKED_RS03235
uniprot id: D1BB58
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446469:SKED RS18550
gene id: 446469:SKED_RS18550
uniprot id: D1BGD7
names: Similarity
messages: Belongs to the peptidase S51 family.

446469:SKED RS13810
gene id: 446469:SKED_RS13810
uniprot id: D1BB16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

446469:SKED RS11595
gene id: 446469:SKED_RS11595
uniprot id: D1BJ84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

446469:SKED RS11505
gene id: 446469:SKED_RS11505
uniprot id: D1BJ65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

446469:SKED RS10190
gene id: 446469:SKED_RS10190
uniprot id: D1BHT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS08640
gene id: 446469:SKED_RS08640
uniprot id: D1BGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS19290
gene id: 446469:SKED_RS19290
uniprot id: D1BFI9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

446469:SKED RS09790
gene id: 446469:SKED_RS09790
uniprot id: D1BHK2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

446469:SKED RS14480
gene id: 446469:SKED_RS14480
uniprot id: D1BBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

446469:SKED RS00100
gene id: 446469:SKED_RS00100
uniprot id: D1BI24
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS02985
gene id: 446469:SKED_RS02985
uniprot id: D1BAM0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS10945
gene id: 446469:SKED_RS10945
uniprot id: D1BIG8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

446469:SKED RS12070
gene id: 446469:SKED_RS12070
uniprot id: D1BJW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

446469:SKED RS01000
gene id: 446469:SKED_RS01000
uniprot id: D1BIY4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446469:SKED RS02160
gene id: 446469:SKED_RS02160
uniprot id: D1BKD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

446469:SKED RS07515
gene id: 446469:SKED_RS07515
uniprot id: D1BFV7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446469:SKED RS06155
gene id: 446469:SKED_RS06155
uniprot id: D1BEC1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

446469:SKED RS00635
gene id: 446469:SKED_RS00635
uniprot id: D1BIR4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

446469:SKED RS08680
gene id: 446469:SKED_RS08680
uniprot id: D1BGX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

446469:SKED RS16855
gene id: 446469:SKED_RS16855
uniprot id: D1BEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS04920
gene id: 446469:SKED_RS04920
uniprot id: D1BCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

446469:SKED RS00850
gene id: 446469:SKED_RS00850
uniprot id: D1BIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS00075
gene id: 446469:SKED_RS00075
uniprot id: D1BI19
names: Similarity
messages: Belongs to the UPF0749 family.

446469:SKED RS05525
gene id: 446469:SKED_RS05525
uniprot id: D1BDL0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

446469:SKED RS11330
gene id: 446469:SKED_RS11330
uniprot id: D1BJ30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS06370
gene id: 446469:SKED_RS06370
uniprot id: D1BEG3
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS07655
gene id: 446469:SKED_RS07655
uniprot id: D1BFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

446469:SKED RS08085
gene id: 446469:SKED_RS08085
uniprot id: D1BGK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS07495
gene id: 446469:SKED_RS07495
uniprot id: D1BFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

446469:SKED RS03085
gene id: 446469:SKED_RS03085
uniprot id: D1BAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11345
gene id: 446469:SKED_RS11345
uniprot id: D1BJ33
names: Similarity
messages: Belongs to the heat shock protein 90 family.

446469:SKED RS11195
gene id: 446469:SKED_RS11195
uniprot id: D1BIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

446469:SKED RS17255
gene id: 446469:SKED_RS17255
uniprot id: D1BEW6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

446469:SKED RS05175
gene id: 446469:SKED_RS05175
uniprot id: D1BD06
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

446469:SKED RS06410
gene id: 446469:SKED_RS06410
uniprot id: D1BEH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

446469:SKED RS00255
gene id: 446469:SKED_RS00255
uniprot id: D1BI53
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446469:SKED RS16115
gene id: 446469:SKED_RS16115
uniprot id: D1BDV4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446469:SKED RS17915
gene id: 446469:SKED_RS17915
uniprot id: D1BFM8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

446469:SKED RS18545
gene id: 446469:SKED_RS18545
uniprot id: D1BGD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

446469:SKED RS04100
gene id: 446469:SKED_RS04100
uniprot id: D1BC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS09375
gene id: 446469:SKED_RS09375
uniprot id: D1BHB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446469:SKED RS07650
gene id: 446469:SKED_RS07650
uniprot id: D1BFY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

446469:SKED RS10285
gene id: 446469:SKED_RS10285
uniprot id: D1BHV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

446469:SKED RS13270
gene id: 446469:SKED_RS13270
uniprot id: D1BAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

446469:SKED RS05715
gene id: 446469:SKED_RS05715
uniprot id: D1BDP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS06700
gene id: 446469:SKED_RS06700
uniprot id: D1BF10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS11385
gene id: 446469:SKED_RS11385
uniprot id: D1BJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

446469:SKED RS13510
gene id: 446469:SKED_RS13510
uniprot id: D1BAV5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446469:SKED RS02300
gene id: 446469:SKED_RS02300
uniprot id: D1BKF7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

446469:SKED RS10445
gene id: 446469:SKED_RS10445
uniprot id: D1BHX8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

446469:SKED RS14650
gene id: 446469:SKED_RS14650
uniprot id: D1BCA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

446469:SKED RS17150
gene id: 446469:SKED_RS17150
uniprot id: D1BEU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS06175
gene id: 446469:SKED_RS06175
uniprot id: D1BEC5
names: Similarity
messages: Belongs to the UPF0225 family.

446469:SKED RS04985
gene id: 446469:SKED_RS04985
uniprot id: D1BCX0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

446469:SKED RS11550
gene id: 446469:SKED_RS11550
uniprot id: D1BJ75
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS11750
gene id: 446469:SKED_RS11750
uniprot id: D1BJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

446469:SKED RS01215
gene id: 446469:SKED_RS01215
uniprot id: D1BJG1
names: Subcellular Location Annotation
messages: Cytoplasm

446469:SKED RS13720
gene id: 446469:SKED_RS13720
uniprot id: D1BAZ8
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS13555
gene id: 446469:SKED_RS13555
uniprot id: D1BAW5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446469:SKED RS07005
gene id: 446469:SKED_RS07005
uniprot id: D1BF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS13325
gene id: 446469:SKED_RS13325
uniprot id: D1BAS0
names: Similarity
messages: Belongs to the asp23 family.

446469:SKED RS09995
gene id: 446469:SKED_RS09995
uniprot id: D1BHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

446469:SKED RS12475
gene id: 446469:SKED_RS12475
uniprot id: D1BK36
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

446469:SKED RS03020
gene id: 446469:SKED_RS03020
uniprot id: D1BAM8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS08735
gene id: 446469:SKED_RS08735
uniprot id: D1BGY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

446469:SKED RS15135
gene id: 446469:SKED_RS15135
uniprot id: D1BCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

446469:SKED RS17955
gene id: 446469:SKED_RS17955
uniprot id: D1BFN6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446469:SKED RS04715
gene id: 446469:SKED_RS04715
uniprot id: D1BCR7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

446469:SKED RS08655
gene id: 446469:SKED_RS08655
uniprot id: D1BGX2
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

446469:SKED RS14080
gene id: 446469:SKED_RS14080
uniprot id: D1BBK0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446469:SKED RS17080
gene id: 446469:SKED_RS17080
uniprot id: D1BET0
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

446469:SKED RS16315
gene id: 446469:SKED_RS16315
uniprot id: D1BDZ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446469:SKED RS11680
gene id: 446469:SKED_RS11680
uniprot id: D1BJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

446469:SKED RS05330
gene id: 446469:SKED_RS05330
uniprot id: D1BDH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446469:SKED RS19150
gene id: 446469:SKED_RS19150
uniprot id: D1BCE4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

446469:SKED RS16245
gene id: 446469:SKED_RS16245
uniprot id: D1BDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS09250
gene id: 446469:SKED_RS09250
uniprot id: D1BH90
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446469:SKED RS12600
gene id: 446469:SKED_RS12600
uniprot id: D1BK61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

446469:SKED RS04580
gene id: 446469:SKED_RS04580
uniprot id: D1BCP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

446469:SKED RS08880
gene id: 446469:SKED_RS08880
uniprot id: D1BH18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

446469:SKED RS05185
gene id: 446469:SKED_RS05185
uniprot id: D1BDE4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

446469:SKED RS00595
gene id: 446469:SKED_RS00595
uniprot id: D1BIQ5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446469:SKED RS18310
gene id: 446469:SKED_RS18310
uniprot id: D1BG90
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446469:SKED RS10380
gene id: 446469:SKED_RS10380
uniprot id: D1BHW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS18930
gene id: 446469:SKED_RS18930
uniprot id: D1BFR8
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS05095
gene id: 446469:SKED_RS05095
uniprot id: D1BCZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

446469:SKED RS15775
gene id: 446469:SKED_RS15775
uniprot id: D1BDA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

446469:SKED RS17650
gene id: 446469:SKED_RS17650
uniprot id: D1BFH6
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

446469:SKED RS15905
gene id: 446469:SKED_RS15905
uniprot id: D1BDC9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS14365
gene id: 446469:SKED_RS14365
uniprot id: D1BBQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS10400
gene id: 446469:SKED_RS10400
uniprot id: D1BHX1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

446469:SKED RS04615
gene id: 446469:SKED_RS04615
uniprot id: D1BCP7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

446469:SKED RS11060
gene id: 446469:SKED_RS11060
uniprot id: D1BIJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

446469:SKED RS05435
gene id: 446469:SKED_RS05435
uniprot id: D1BDJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

446469:SKED RS05770
gene id: 446469:SKED_RS05770
uniprot id: D1BDQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

446469:SKED RS12860
gene id: 446469:SKED_RS12860
uniprot id: D1BKP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS13315
gene id: 446469:SKED_RS13315
uniprot id: D1BAR8
names: Similarity
messages: Belongs to the asp23 family.

446469:SKED RS11140
gene id: 446469:SKED_RS11140
uniprot id: D1BIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

446469:SKED RS11210
gene id: 446469:SKED_RS11210
uniprot id: D1BIM3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS18485
gene id: 446469:SKED_RS18485
uniprot id: D1BGC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS03355
gene id: 446469:SKED_RS03355
uniprot id: D1BB82
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

446469:SKED RS12015
gene id: 446469:SKED_RS12015
uniprot id: D1BJV2
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS12735
gene id: 446469:SKED_RS12735
uniprot id: D1BKM2
names: Similarity
messages: Belongs to the LOG family.

446469:SKED RS19765
gene id: 446469:SKED_RS19765
uniprot id: D1BK01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

446469:SKED RS05570
gene id: 446469:SKED_RS05570
uniprot id: D1BDL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

446469:SKED RS13860
gene id: 446469:SKED_RS13860
uniprot id: D1BB26
names: Similarity
messages: Belongs to the peptidase S66 family.

446469:SKED RS08610
gene id: 446469:SKED_RS08610
uniprot id: D1BGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446469:SKED RS09480
gene id: 446469:SKED_RS09480
uniprot id: D1BHD8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446469:SKED RS14525
gene id: 446469:SKED_RS14525
uniprot id: D1BBU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

446469:SKED RS11135
gene id: 446469:SKED_RS11135
uniprot id: D1BIK8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

446469:SKED RS00750
gene id: 446469:SKED_RS00750
uniprot id: D1BIT7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS11545
gene id: 446469:SKED_RS11545
uniprot id: D1BJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

446469:SKED RS05985
gene id: 446469:SKED_RS05985
uniprot id: D1BE85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS06595
gene id: 446469:SKED_RS06595
uniprot id: D1BEY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

446469:SKED RS14040
gene id: 446469:SKED_RS14040
uniprot id: D1BBJ2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

446469:SKED RS04620
gene id: 446469:SKED_RS04620
uniprot id: D1BCP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

446469:SKED RS05590
gene id: 446469:SKED_RS05590
uniprot id: D1BDM3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

446469:SKED RS17820
gene id: 446469:SKED_RS17820
uniprot id: D1BFK9
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS11845
gene id: 446469:SKED_RS11845
uniprot id: D1BJD4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446469:SKED RS14920
gene id: 446469:SKED_RS14920
uniprot id: D1BCF1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446469:SKED RS03250
gene id: 446469:SKED_RS03250
uniprot id: D1BB61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS03455
gene id: 446469:SKED_RS03455
uniprot id: D1BB99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS09035
gene id: 446469:SKED_RS09035
uniprot id: D1BH48
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS07840
gene id: 446469:SKED_RS07840
uniprot id: D1BG25
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

446469:SKED RS08295
gene id: 446469:SKED_RS08295
uniprot id: D1BGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS04295
gene id: 446469:SKED_RS04295
uniprot id: D1BC51
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

446469:SKED RS17940
gene id: 446469:SKED_RS17940
uniprot id: D1BFN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

446469:SKED RS12020
gene id: 446469:SKED_RS12020
uniprot id: D1BJV3
names: Similarity
messages: Belongs to the FPG family.

446469:SKED RS03965
gene id: 446469:SKED_RS03965
uniprot id: D1BBY4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

446469:SKED RS01920
gene id: 446469:SKED_RS01920
uniprot id: D1BK83
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446469:SKED RS17265
gene id: 446469:SKED_RS17265
uniprot id: D1BEW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

446469:SKED RS18450
gene id: 446469:SKED_RS18450
uniprot id: D1BGB7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

446469:SKED RS06805
gene id: 446469:SKED_RS06805
uniprot id: D1BF31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

446469:SKED RS02295
gene id: 446469:SKED_RS02295
uniprot id: D1BKF6
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

446469:SKED RS03340
gene id: 446469:SKED_RS03340
uniprot id: D1BB79
names: Similarity
messages: Belongs to the Nth/MutY family.

446469:SKED RS17725
gene id: 446469:SKED_RS17725
uniprot id: D1BFJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS00740
gene id: 446469:SKED_RS00740
uniprot id: D1BIT5
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS09740
gene id: 446469:SKED_RS09740
uniprot id: D1BHJ2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

446469:SKED RS04835
gene id: 446469:SKED_RS04835
uniprot id: D1BCU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

446469:SKED RS16455
gene id: 446469:SKED_RS16455
uniprot id: D1BE24
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

446469:SKED RS15485
gene id: 446469:SKED_RS15485
uniprot id: D1BD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS06695
gene id: 446469:SKED_RS06695
uniprot id: D1BF09
names: Similarity
messages: Belongs to the Fur family.

446469:SKED RS00015
gene id: 446469:SKED_RS00015
uniprot id: D1BI08
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

446469:SKED RS06485
gene id: 446469:SKED_RS06485
uniprot id: D1BEI5
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS04205
gene id: 446469:SKED_RS04205
uniprot id: D1BC33
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

446469:SKED RS14550
gene id: 446469:SKED_RS14550
uniprot id: D1BBU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

446469:SKED RS01410
gene id: 446469:SKED_RS01410
uniprot id: D1BJK0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

446469:SKED RS05620
gene id: 446469:SKED_RS05620
uniprot id: D1BDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

446469:SKED RS14730
gene id: 446469:SKED_RS14730
uniprot id: D1BCB5
names: Similarity
messages: Belongs to the MYG1 family.

446469:SKED RS12505
gene id: 446469:SKED_RS12505
uniprot id: D1BK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

446469:SKED RS07560
gene id: 446469:SKED_RS07560
uniprot id: D1BFW9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

446469:SKED RS02900
gene id: 446469:SKED_RS02900
uniprot id: D1BAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS16270
gene id: 446469:SKED_RS16270
uniprot id: D1BDY5
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS17220
gene id: 446469:SKED_RS17220
uniprot id: D1BEV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446469:SKED RS05210
gene id: 446469:SKED_RS05210
uniprot id: D1BDE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS08005
gene id: 446469:SKED_RS08005
uniprot id: D1BGJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

446469:SKED RS15510
gene id: 446469:SKED_RS15510
uniprot id: D1BD51
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

446469:SKED RS01505
gene id: 446469:SKED_RS01505
uniprot id: D1BJL8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

446469:SKED RS13015
gene id: 446469:SKED_RS13015
uniprot id: D1BKS9
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

446469:SKED RS06150
gene id: 446469:SKED_RS06150
uniprot id: D1BEC0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

446469:SKED RS18190
gene id: 446469:SKED_RS18190
uniprot id: D1BG69
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446469:SKED RS05660
gene id: 446469:SKED_RS05660
uniprot id: D1BDN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS17960
gene id: 446469:SKED_RS17960
uniprot id: D1BFN7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446469:SKED RS06475
gene id: 446469:SKED_RS06475
uniprot id: D1BEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS02190
gene id: 446469:SKED_RS02190
uniprot id: D1BKD7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

446469:SKED RS13540
gene id: 446469:SKED_RS13540
uniprot id: D1BAW2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446469:SKED RS08600
gene id: 446469:SKED_RS08600
uniprot id: D1BGW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

446469:SKED RS18600
gene id: 446469:SKED_RS18600
uniprot id: D1BGE7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

446469:SKED RS16440
gene id: 446469:SKED_RS16440
uniprot id: D1BE21
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446469:SKED RS14460
gene id: 446469:SKED_RS14460
uniprot id: D1BBS7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

446469:SKED RS18285
gene id: 446469:SKED_RS18285
uniprot id: D1BG85
names: Similarity
messages: Belongs to the asparaginase 1 family.

446469:SKED RS08245
gene id: 446469:SKED_RS08245
uniprot id: D1BGN4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446469:SKED RS15385
gene id: 446469:SKED_RS15385
uniprot id: D1BD26
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

446469:SKED RS12540
gene id: 446469:SKED_RS12540
uniprot id: D1BK49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

446469:SKED RS04355
gene id: 446469:SKED_RS04355
uniprot id: D1BC63
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

446469:SKED RS10210
gene id: 446469:SKED_RS10210
uniprot id: D1BHT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

446469:SKED RS14845
gene id: 446469:SKED_RS14845
uniprot id: D1BCD7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446469:SKED RS03795
gene id: 446469:SKED_RS03795
uniprot id: D1BBG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

446469:SKED RS15480
gene id: 446469:SKED_RS15480
uniprot id: D1BD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11290
gene id: 446469:SKED_RS11290
uniprot id: D1BJ22
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

446469:SKED RS08875
gene id: 446469:SKED_RS08875
uniprot id: D1BH17
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

446469:SKED RS14455
gene id: 446469:SKED_RS14455
uniprot id: D1BBS6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

446469:SKED RS14755
gene id: 446469:SKED_RS14755
uniprot id: D1BCC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

446469:SKED RS12365
gene id: 446469:SKED_RS12365
uniprot id: D1BK14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

446469:SKED RS18555
gene id: 446469:SKED_RS18555
uniprot id: D1BGD8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

446469:SKED RS03125
gene id: 446469:SKED_RS03125
uniprot id: D1BAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS08755
gene id: 446469:SKED_RS08755
uniprot id: D1BGZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

446469:SKED RS13640
gene id: 446469:SKED_RS13640
uniprot id: D1BAY2
names: Similarity
messages: Belongs to the peptidase M24B family.

446469:SKED RS04890
gene id: 446469:SKED_RS04890
uniprot id: D1BCV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

446469:SKED RS09830
gene id: 446469:SKED_RS09830
uniprot id: D1BHL0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

446469:SKED RS05060
gene id: 446469:SKED_RS05060
uniprot id: D1BCY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

446469:SKED RS02435
gene id: 446469:SKED_RS02435
uniprot id: D1BKI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS08160
gene id: 446469:SKED_RS08160
uniprot id: D1BGM4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446469:SKED RS15505
gene id: 446469:SKED_RS15505
uniprot id: D1BD50
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS14575
gene id: 446469:SKED_RS14575
uniprot id: D1BBV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

446469:SKED RS03015
gene id: 446469:SKED_RS03015
uniprot id: D1BAM7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS04290
gene id: 446469:SKED_RS04290
uniprot id: D1BC50
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

446469:SKED RS06650
gene id: 446469:SKED_RS06650
uniprot id: D1BF00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

446469:SKED RS14030
gene id: 446469:SKED_RS14030
uniprot id: D1BBJ0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

446469:SKED RS17770
gene id: 446469:SKED_RS17770
uniprot id: D1BFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

446469:SKED RS14380
gene id: 446469:SKED_RS14380
uniprot id: D1BBR1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS05005
gene id: 446469:SKED_RS05005
uniprot id: D1BCX4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

446469:SKED RS04875
gene id: 446469:SKED_RS04875
uniprot id: D1BCU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

446469:SKED RS07290
gene id: 446469:SKED_RS07290
uniprot id: D1BFR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446469:SKED RS06145
gene id: 446469:SKED_RS06145
uniprot id: D1BEB9
names: Function
names: Similarity
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

446469:SKED RS04025
gene id: 446469:SKED_RS04025
uniprot id: D1BBZ6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

446469:SKED RS18645
gene id: 446469:SKED_RS18645
uniprot id: D1BGF6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446469:SKED RS09430
gene id: 446469:SKED_RS09430
uniprot id: D1BHC7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS13905
gene id: 446469:SKED_RS13905
uniprot id: D1BB35
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS04850
gene id: 446469:SKED_RS04850
uniprot id: D1BCU3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

446469:SKED RS03430
gene id: 446469:SKED_RS03430
uniprot id: D1BB93
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS11865
gene id: 446469:SKED_RS11865
uniprot id: D1BJD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS12725
gene id: 446469:SKED_RS12725
uniprot id: D1BKL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

446469:SKED RS12060
gene id: 446469:SKED_RS12060
uniprot id: D1BJW1
names: Similarity
messages: Belongs to the peptidase M1 family.

446469:SKED RS07485
gene id: 446469:SKED_RS07485
uniprot id: D1BFV1
names: Similarity
messages: Belongs to the glutamine synthetase family.

446469:SKED RS12390
gene id: 446469:SKED_RS12390
uniprot id: D1BK19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

446469:SKED RS03610
gene id: 446469:SKED_RS03610
uniprot id: D1BBD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446469:SKED RS12255
gene id: 446469:SKED_RS12255
uniprot id: D1BJZ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS01665
gene id: 446469:SKED_RS01665
uniprot id: D1BJQ0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

446469:SKED RS09370
gene id: 446469:SKED_RS09370
uniprot id: D1BHB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446469:SKED RS08785
gene id: 446469:SKED_RS08785
uniprot id: D1BGZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

446469:SKED RS17930
gene id: 446469:SKED_RS17930
uniprot id: D1BFN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

446469:SKED RS08905
gene id: 446469:SKED_RS08905
uniprot id: D1BH23
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

446469:SKED RS09275
gene id: 446469:SKED_RS09275
uniprot id: D1BH95
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

446469:SKED RS07570
gene id: 446469:SKED_RS07570
uniprot id: D1BFX1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

446469:SKED RS01775
gene id: 446469:SKED_RS01775
uniprot id: D1BJS4
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

446469:SKED RS06685
gene id: 446469:SKED_RS06685
uniprot id: D1BF07
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS07330
gene id: 446469:SKED_RS07330
uniprot id: D1BFR9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

446469:SKED RS12635
gene id: 446469:SKED_RS12635
uniprot id: D1BKK1
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS05140
gene id: 446469:SKED_RS05140
uniprot id: D1BD02
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS11375
gene id: 446469:SKED_RS11375
uniprot id: D1BJ39
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

446469:SKED RS18700
gene id: 446469:SKED_RS18700
uniprot id: D1BGU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

446469:SKED RS05445
gene id: 446469:SKED_RS05445
uniprot id: D1BDJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS14545
gene id: 446469:SKED_RS14545
uniprot id: D1BBU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

446469:SKED RS05845
gene id: 446469:SKED_RS05845
uniprot id: D1BDS4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS02310
gene id: 446469:SKED_RS02310
uniprot id: D1BKF9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

446469:SKED RS13230
gene id: 446469:SKED_RS13230
uniprot id: D1BKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

446469:SKED RS07595
gene id: 446469:SKED_RS07595
uniprot id: D1BFX6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446469:SKED RS04320
gene id: 446469:SKED_RS04320
uniprot id: D1BC56
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446469:SKED RS15800
gene id: 446469:SKED_RS15800
uniprot id: D1BDA8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446469:SKED RS14605
gene id: 446469:SKED_RS14605
uniprot id: D1BBV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

446469:SKED RS15345
gene id: 446469:SKED_RS15345
uniprot id: D1BD18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

446469:SKED RS08635
gene id: 446469:SKED_RS08635
uniprot id: D1BGW8
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

446469:SKED RS14015
gene id: 446469:SKED_RS14015
uniprot id: D1BBI7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446469:SKED RS14020
gene id: 446469:SKED_RS14020
uniprot id: D1BBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

446469:SKED RS08790
gene id: 446469:SKED_RS08790
uniprot id: D1BGZ9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

446469:SKED RS15445
gene id: 446469:SKED_RS15445
uniprot id: D1BD38
names: Similarity
messages: Belongs to the PspA/IM30 family.

446469:SKED RS13610
gene id: 446469:SKED_RS13610
uniprot id: D1BAX6
names: Similarity
messages: Belongs to the DEAD box helicase family.

446469:SKED RS07215
gene id: 446469:SKED_RS07215
uniprot id: D1BFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

446469:SKED RS15270
gene id: 446469:SKED_RS15270
uniprot id: D1BCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

446469:SKED RS09445
gene id: 446469:SKED_RS09445
uniprot id: D1BHD1
names: Similarity
messages: Belongs to the barstar family.

446469:SKED RS09770
gene id: 446469:SKED_RS09770
uniprot id: D1BHJ8
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

446469:SKED RS02635
gene id: 446469:SKED_RS02635
uniprot id: D1BAF0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS08915
gene id: 446469:SKED_RS08915
uniprot id: D1BH25
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

446469:SKED RS17710
gene id: 446469:SKED_RS17710
uniprot id: D1BFI8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

446469:SKED RS17330
gene id: 446469:SKED_RS17330
uniprot id: D1BFB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

446469:SKED RS15240
gene id: 446469:SKED_RS15240
uniprot id: D1BCL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

446469:SKED RS01445
gene id: 446469:SKED_RS01445
uniprot id: D1BJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS03460
gene id: 446469:SKED_RS03460
uniprot id: D1BBA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS01140
gene id: 446469:SKED_RS01140
uniprot id: D1BJ10
names: Similarity
messages: Belongs to the peptidase C69 family.

446469:SKED RS10960
gene id: 446469:SKED_RS10960
uniprot id: D1BIH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

446469:SKED RS11650
gene id: 446469:SKED_RS11650
uniprot id: D1BJ95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

446469:SKED RS16045
gene id: 446469:SKED_RS16045
uniprot id: D1BDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

446469:SKED RS05225
gene id: 446469:SKED_RS05225
uniprot id: D1BDF2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

446469:SKED RS14800
gene id: 446469:SKED_RS14800
uniprot id: D1BCC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

446469:SKED RS03605
gene id: 446469:SKED_RS03605
uniprot id: D1BBC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446469:SKED RS01325
gene id: 446469:SKED_RS01325
uniprot id: D1BJI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

446469:SKED RS15705
gene id: 446469:SKED_RS15705
uniprot id: D1BD89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS11905
gene id: 446469:SKED_RS11905
uniprot id: D1BJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS04995
gene id: 446469:SKED_RS04995
uniprot id: D1BCX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

446469:SKED RS03310
gene id: 446469:SKED_RS03310
uniprot id: D1BB73
names: Similarity
messages: Belongs to the peptidase S33 family.

446469:SKED RS15055
gene id: 446469:SKED_RS15055
uniprot id: D1BCH7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS13920
gene id: 446469:SKED_RS13920
uniprot id: D1BB38
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

446469:SKED RS18570
gene id: 446469:SKED_RS18570
uniprot id: D1BGE1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

446469:SKED RS08845
gene id: 446469:SKED_RS08845
uniprot id: D1BH11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446469:SKED RS03725
gene id: 446469:SKED_RS03725
uniprot id: D1BBF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

446469:SKED RS11010
gene id: 446469:SKED_RS11010
uniprot id: D1BII2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

446469:SKED RS07580
gene id: 446469:SKED_RS07580
uniprot id: D1BFX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

446469:SKED RS06895
gene id: 446469:SKED_RS06895
uniprot id: D1BF47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

446469:SKED RS03320
gene id: 446469:SKED_RS03320
uniprot id: D1BB75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

446469:SKED RS06990
gene id: 446469:SKED_RS06990
uniprot id: D1BF65
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

446469:SKED RS01820
gene id: 446469:SKED_RS01820
uniprot id: D1BJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS10575
gene id: 446469:SKED_RS10575
uniprot id: D1BI04
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS09775
gene id: 446469:SKED_RS09775
uniprot id: D1BHJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

446469:SKED RS14980
gene id: 446469:SKED_RS14980
uniprot id: D1BCG3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

446469:SKED RS01395
gene id: 446469:SKED_RS01395
uniprot id: D1BJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS18350
gene id: 446469:SKED_RS18350
uniprot id: D1BG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446469:SKED RS04960
gene id: 446469:SKED_RS04960
uniprot id: D1BCW5
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

446469:SKED RS17315
gene id: 446469:SKED_RS17315
uniprot id: D1BFB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

446469:SKED RS07740
gene id: 446469:SKED_RS07740
uniprot id: D1BG05
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

446469:SKED RS02975
gene id: 446469:SKED_RS02975
uniprot id: D1BAL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

446469:SKED RS17415
gene id: 446469:SKED_RS17415
uniprot id: D1BFD0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS00180
gene id: 446469:SKED_RS00180
uniprot id: D1BI39
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446469:SKED RS09815
gene id: 446469:SKED_RS09815
uniprot id: D1BHK7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

446469:SKED RS08040
gene id: 446469:SKED_RS08040
uniprot id: D1BGJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

446469:SKED RS14725
gene id: 446469:SKED_RS14725
uniprot id: D1BCB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

446469:SKED RS15625
gene id: 446469:SKED_RS15625
uniprot id: D1BD73
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

446469:SKED RS16155
gene id: 446469:SKED_RS16155
uniprot id: D1BDW2
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

446469:SKED RS08605
gene id: 446469:SKED_RS08605
uniprot id: D1BGW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446469:SKED RS10440
gene id: 446469:SKED_RS10440
uniprot id: D1BHX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

446469:SKED RS11475
gene id: 446469:SKED_RS11475
uniprot id: D1BJ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

446469:SKED RS15720
gene id: 446469:SKED_RS15720
uniprot id: D1BD92
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

446469:SKED RS14495
gene id: 446469:SKED_RS14495
uniprot id: D1BBT4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446469:SKED RS04475
gene id: 446469:SKED_RS04475
uniprot id: D1BC86
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS03990
gene id: 446469:SKED_RS03990
uniprot id: D1BBY9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

446469:SKED RS10990
gene id: 446469:SKED_RS10990
uniprot id: D1BIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

446469:SKED RS02245
gene id: 446469:SKED_RS02245
uniprot id: D1BKE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446469:SKED RS11205
gene id: 446469:SKED_RS11205
uniprot id: D1BIM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

446469:SKED RS10795
gene id: 446469:SKED_RS10795
uniprot id: D1BIE2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS08980
gene id: 446469:SKED_RS08980
uniprot id: D1BH38
names: Similarity
messages: Belongs to the AHA1 family.

446469:SKED RS04335
gene id: 446469:SKED_RS04335
uniprot id: D1BC59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS00600
gene id: 446469:SKED_RS00600
uniprot id: D1BIQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

446469:SKED RS00940
gene id: 446469:SKED_RS00940
uniprot id: D1BIX3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

446469:SKED RS05105
gene id: 446469:SKED_RS05105
uniprot id: D1BCZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS17050
gene id: 446469:SKED_RS17050
uniprot id: D1BES3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446469:SKED RS15190
gene id: 446469:SKED_RS15190
uniprot id: D1BCK4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS12560
gene id: 446469:SKED_RS12560
uniprot id: D1BK53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

446469:SKED RS15670
gene id: 446469:SKED_RS15670
uniprot id: D1BD82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

446469:SKED RS12210
gene id: 446469:SKED_RS12210
uniprot id: D1BJY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

446469:SKED RS17030
gene id: 446469:SKED_RS17030
uniprot id: D1BER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11075
gene id: 446469:SKED_RS11075
uniprot id: D1BIJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

446469:SKED RS12045
gene id: 446469:SKED_RS12045
uniprot id: D1BJV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446469:SKED RS04745
gene id: 446469:SKED_RS04745
uniprot id: D1BCS2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS10810
gene id: 446469:SKED_RS10810
uniprot id: D1BIE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS13595
gene id: 446469:SKED_RS13595
uniprot id: D1BAX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

446469:SKED RS05180
gene id: 446469:SKED_RS05180
uniprot id: D1BD07
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

446469:SKED RS06540
gene id: 446469:SKED_RS06540
uniprot id: D1BEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446469:SKED RS04060
gene id: 446469:SKED_RS04060
uniprot id: D1BC03
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

446469:SKED RS12260
gene id: 446469:SKED_RS12260
uniprot id: D1BJZ3
names: Similarity
messages: Belongs to the thioredoxin family.

446469:SKED RS09405
gene id: 446469:SKED_RS09405
uniprot id: D1BHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS10095
gene id: 446469:SKED_RS10095
uniprot id: D1BHR2
names: Similarity
messages: Belongs to the leucine-binding protein family.

446469:SKED RS08145
gene id: 446469:SKED_RS08145
uniprot id: D1BGM1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446469:SKED RS11495
gene id: 446469:SKED_RS11495
uniprot id: D1BJ63
names: Similarity
messages: Belongs to the ribF family.

446469:SKED RS10490
gene id: 446469:SKED_RS10490
uniprot id: D1BHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

446469:SKED RS04645
gene id: 446469:SKED_RS04645
uniprot id: D1BCQ3
names: Similarity
messages: Belongs to the GSP E family.

446469:SKED RS18425
gene id: 446469:SKED_RS18425
uniprot id: D1BGB2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS18120
gene id: 446469:SKED_RS18120
uniprot id: D1BG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS10820
gene id: 446469:SKED_RS10820
uniprot id: D1BIE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

446469:SKED RS07125
gene id: 446469:SKED_RS07125
uniprot id: D1BF93
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

446469:SKED RS00735
gene id: 446469:SKED_RS00735
uniprot id: D1BIT4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS03525
gene id: 446469:SKED_RS03525
uniprot id: D1BBB3
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS15835
gene id: 446469:SKED_RS15835
uniprot id: D1BDB5
names: Similarity
messages: Belongs to the UPF0045 family.

446469:SKED RS18040
gene id: 446469:SKED_RS18040
uniprot id: D1BG39
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS02555
gene id: 446469:SKED_RS02555
uniprot id: D1BAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS09885
gene id: 446469:SKED_RS09885
uniprot id: D1BHM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

446469:SKED RS06960
gene id: 446469:SKED_RS06960
uniprot id: D1BF59
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446469:SKED RS02345
gene id: 446469:SKED_RS02345
uniprot id: D1BKG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

446469:SKED RS13940
gene id: 446469:SKED_RS13940
uniprot id: D1BB42
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446469:SKED RS04130
gene id: 446469:SKED_RS04130
uniprot id: D1BC18
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS15275
gene id: 446469:SKED_RS15275
uniprot id: D1BCM1
names: Similarity
messages: Belongs to the MotB family.

446469:SKED RS18005
gene id: 446469:SKED_RS18005
uniprot id: D1BG32
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS11020
gene id: 446469:SKED_RS11020
uniprot id: D1BII4
names: Similarity
messages: Belongs to the catalase family.

446469:SKED RS00230
gene id: 446469:SKED_RS00230
uniprot id: D1BI49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446469:SKED RS04015
gene id: 446469:SKED_RS04015
uniprot id: D1BBZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

446469:SKED RS01020
gene id: 446469:SKED_RS01020
uniprot id: D1BIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11855
gene id: 446469:SKED_RS11855
uniprot id: D1BJD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS17160
gene id: 446469:SKED_RS17160
uniprot id: D1BEU6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

446469:SKED RS00855
gene id: 446469:SKED_RS00855
uniprot id: D1BIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS08370
gene id: 446469:SKED_RS08370
uniprot id: D1BGQ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446469:SKED RS12840
gene id: 446469:SKED_RS12840
uniprot id: D1BKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS10935
gene id: 446469:SKED_RS10935
uniprot id: D1BIG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

446469:SKED RS16010
gene id: 446469:SKED_RS16010
uniprot id: D1BDT3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

446469:SKED RS10930
gene id: 446469:SKED_RS10930
uniprot id: D1BIG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS11470
gene id: 446469:SKED_RS11470
uniprot id: D1BJ58
names: Similarity
messages: Belongs to the peptidase M16 family.

446469:SKED RS15895
gene id: 446469:SKED_RS15895
uniprot id: D1BDC7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS00275
gene id: 446469:SKED_RS00275
uniprot id: D1BI57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

446469:SKED RS01400
gene id: 446469:SKED_RS01400
uniprot id: D1BJJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS14625
gene id: 446469:SKED_RS14625
uniprot id: D1BC95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

446469:SKED RS02450
gene id: 446469:SKED_RS02450
uniprot id: D1BKI8
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS09050
gene id: 446469:SKED_RS09050
uniprot id: D1BH51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

446469:SKED RS11990
gene id: 446469:SKED_RS11990
uniprot id: D1BJU7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

446469:SKED RS07770
gene id: 446469:SKED_RS07770
uniprot id: D1BG11
names: Similarity
messages: Belongs to the universal stress protein A family.

446469:SKED RS11500
gene id: 446469:SKED_RS11500
uniprot id: D1BJ64
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

446469:SKED RS15490
gene id: 446469:SKED_RS15490
uniprot id: D1BD47
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

446469:SKED RS04090
gene id: 446469:SKED_RS04090
uniprot id: D1BC10
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

446469:SKED RS18300
gene id: 446469:SKED_RS18300
uniprot id: D1BG88
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS14530
gene id: 446469:SKED_RS14530
uniprot id: D1BBU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

446469:SKED RS18560
gene id: 446469:SKED_RS18560
uniprot id: D1BGD9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

446469:SKED RS01815
gene id: 446469:SKED_RS01815
uniprot id: D1BJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11565
gene id: 446469:SKED_RS11565
uniprot id: D1BJ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

446469:SKED RS00010
gene id: 446469:SKED_RS00010
uniprot id: D1BI07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

446469:SKED RS02965
gene id: 446469:SKED_RS02965
uniprot id: D1BAL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

446469:SKED RS00555
gene id: 446469:SKED_RS00555
uniprot id: D1BIP6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

446469:SKED RS17805
gene id: 446469:SKED_RS17805
uniprot id: D1BFK7
names: Function
names: Similarity
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

446469:SKED RS03200
gene id: 446469:SKED_RS03200
uniprot id: D1BB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11015
gene id: 446469:SKED_RS11015
uniprot id: D1BII3
names: Similarity
messages: Belongs to the Fur family.

446469:SKED RS00745
gene id: 446469:SKED_RS00745
uniprot id: D1BIT6
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS17320
gene id: 446469:SKED_RS17320
uniprot id: D1BFB2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

446469:SKED RS05405
gene id: 446469:SKED_RS05405
uniprot id: D1BDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

446469:SKED RS15360
gene id: 446469:SKED_RS15360
uniprot id: D1BD21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

446469:SKED RS07735
gene id: 446469:SKED_RS07735
uniprot id: D1BG04
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

446469:SKED RS06315
gene id: 446469:SKED_RS06315
uniprot id: D1BEF3
names: Similarity
messages: Belongs to the thymidine kinase family.

446469:SKED RS02230
gene id: 446469:SKED_RS02230
uniprot id: D1BKE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

446469:SKED RS14055
gene id: 446469:SKED_RS14055
uniprot id: D1BBJ5
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

446469:SKED RS00065
gene id: 446469:SKED_RS00065
uniprot id: D1BI17
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS05460
gene id: 446469:SKED_RS05460
uniprot id: D1BDJ7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446469:SKED RS13185
gene id: 446469:SKED_RS13185
uniprot id: D1BKW4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS09240
gene id: 446469:SKED_RS09240
uniprot id: D1BH88
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

446469:SKED RS12065
gene id: 446469:SKED_RS12065
uniprot id: D1BJW2
names: Similarity
messages: Belongs to the disproportionating enzyme family.

446469:SKED RS05235
gene id: 446469:SKED_RS05235
uniprot id: D1BDF4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS11605
gene id: 446469:SKED_RS11605
uniprot id: D1BJ86
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

446469:SKED RS18655
gene id: 446469:SKED_RS18655
uniprot id: D1BGF8
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS10140
gene id: 446469:SKED_RS10140
uniprot id: D1BHS1
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

446469:SKED RS07855
gene id: 446469:SKED_RS07855
uniprot id: D1BG28
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

446469:SKED RS09960
gene id: 446469:SKED_RS09960
uniprot id: D1BHN4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS15220
gene id: 446469:SKED_RS15220
uniprot id: D1BCL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

446469:SKED RS13980
gene id: 446469:SKED_RS13980
uniprot id: D1BBI0
names: Similarity
messages: Belongs to the XFP family.

446469:SKED RS05085
gene id: 446469:SKED_RS05085
uniprot id: D1BCZ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446469:SKED RS02390
gene id: 446469:SKED_RS02390
uniprot id: D1BKH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

446469:SKED RS18205
gene id: 446469:SKED_RS18205
uniprot id: D1BG72
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446469:SKED RS00945
gene id: 446469:SKED_RS00945
uniprot id: D1BIX4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

446469:SKED RS17905
gene id: 446469:SKED_RS17905
uniprot id: D1BFM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446469:SKED RS03540
gene id: 446469:SKED_RS03540
uniprot id: D1BBB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

446469:SKED RS09900
gene id: 446469:SKED_RS09900
uniprot id: D1BHM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS08540
gene id: 446469:SKED_RS08540
uniprot id: D1BGU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446469:SKED RS02355
gene id: 446469:SKED_RS02355
uniprot id: D1BKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

446469:SKED RS02670
gene id: 446469:SKED_RS02670
uniprot id: D1BAF7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS07630
gene id: 446469:SKED_RS07630
uniprot id: D1BFY3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

446469:SKED RS02880
gene id: 446469:SKED_RS02880
uniprot id: D1BAJ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS01220
gene id: 446469:SKED_RS01220
uniprot id: D1BJG2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

446469:SKED RS11875
gene id: 446469:SKED_RS11875
uniprot id: D1BJE0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

446469:SKED RS13685
gene id: 446469:SKED_RS13685
uniprot id: D1BAZ1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

446469:SKED RS17345
gene id: 446469:SKED_RS17345
uniprot id: D1BFB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446469:SKED RS03710
gene id: 446469:SKED_RS03710
uniprot id: D1BBF0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS14670
gene id: 446469:SKED_RS14670
uniprot id: D1BCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

446469:SKED RS08615
gene id: 446469:SKED_RS08615
uniprot id: D1BGW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS04080
gene id: 446469:SKED_RS04080
uniprot id: D1BC07
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

446469:SKED RS04690
gene id: 446469:SKED_RS04690
uniprot id: D1BCR2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS05350
gene id: 446469:SKED_RS05350
uniprot id: D1BDH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

446469:SKED RS15015
gene id: 446469:SKED_RS15015
uniprot id: D1BCG9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

446469:SKED RS14515
gene id: 446469:SKED_RS14515
uniprot id: D1BBT8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

446469:SKED RS00800
gene id: 446469:SKED_RS00800
uniprot id: D1BIU6
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS07685
gene id: 446469:SKED_RS07685
uniprot id: D1BFZ4
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

446469:SKED RS09065
gene id: 446469:SKED_RS09065
uniprot id: D1BH54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

446469:SKED RS05870
gene id: 446469:SKED_RS05870
uniprot id: D1BE63
names: Similarity
messages: Belongs to the manganese catalase family.

446469:SKED RS09820
gene id: 446469:SKED_RS09820
uniprot id: D1BHK8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

446469:SKED RS18685
gene id: 446469:SKED_RS18685
uniprot id: D1BGG4
names: Similarity
messages: Belongs to the ParB family.

446469:SKED RS12745
gene id: 446469:SKED_RS12745
uniprot id: D1BKM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

446469:SKED RS06525
gene id: 446469:SKED_RS06525
uniprot id: D1BEJ3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

446469:SKED RS04600
gene id: 446469:SKED_RS04600
uniprot id: D1BCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

446469:SKED RS18015
gene id: 446469:SKED_RS18015
uniprot id: D1BG34
names: Similarity
messages: Belongs to the AHA1 family.

446469:SKED RS11530
gene id: 446469:SKED_RS11530
uniprot id: D1BJ71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS08675
gene id: 446469:SKED_RS08675
uniprot id: D1BGX6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

446469:SKED RS09985
gene id: 446469:SKED_RS09985
uniprot id: D1BHN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446469:SKED RS11125
gene id: 446469:SKED_RS11125
uniprot id: D1BIK6
names: Subcellular Location Annotation
messages: Cytoplasm

446469:SKED RS14470
gene id: 446469:SKED_RS14470
uniprot id: D1BBS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

446469:SKED RS12680
gene id: 446469:SKED_RS12680
uniprot id: D1BKL0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

446469:SKED RS10105
gene id: 446469:SKED_RS10105
uniprot id: D1BHR4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS03415
gene id: 446469:SKED_RS03415
uniprot id: D1BB91
names: Similarity
messages: Belongs to the histone deacetylase family.

446469:SKED RS04865
gene id: 446469:SKED_RS04865
uniprot id: D1BCU6
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS07675
gene id: 446469:SKED_RS07675
uniprot id: D1BFZ2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS11045
gene id: 446469:SKED_RS11045
uniprot id: D1BII9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

446469:SKED RS10050
gene id: 446469:SKED_RS10050
uniprot id: D1BHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS04845
gene id: 446469:SKED_RS04845
uniprot id: D1BCU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

446469:SKED RS17145
gene id: 446469:SKED_RS17145
uniprot id: D1BEU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS10670
gene id: 446469:SKED_RS10670
uniprot id: D1BIB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

446469:SKED RS03615
gene id: 446469:SKED_RS03615
uniprot id: D1BBD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446469:SKED RS17765
gene id: 446469:SKED_RS17765
uniprot id: D1BFJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446469:SKED RS14300
gene id: 446469:SKED_RS14300
uniprot id: D1BBP5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

446469:SKED RS12695
gene id: 446469:SKED_RS12695
uniprot id: D1BKL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS18970
gene id: 446469:SKED_RS18970
uniprot id: D1BH31
names: Similarity
messages: Belongs to the UPF0749 family.

446469:SKED RS10475
gene id: 446469:SKED_RS10475
uniprot id: D1BHY4
names: Similarity
messages: Belongs to the UPF0098 family.

446469:SKED RS14465
gene id: 446469:SKED_RS14465
uniprot id: D1BBS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

446469:SKED RS03205
gene id: 446469:SKED_RS03205
uniprot id: D1BB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS03830
gene id: 446469:SKED_RS03830
uniprot id: D1BBH2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

446469:SKED RS14665
gene id: 446469:SKED_RS14665
uniprot id: D1BCA3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

446469:SKED RS01790
gene id: 446469:SKED_RS01790
uniprot id: D1BJS7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS05695
gene id: 446469:SKED_RS05695
uniprot id: D1BDP4
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446469:SKED RS05690
gene id: 446469:SKED_RS05690
uniprot id: D1BDP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS10500
gene id: 446469:SKED_RS10500
uniprot id: D1BHY9
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

446469:SKED RS18925
gene id: 446469:SKED_RS18925
uniprot id: D1BFR7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS12900
gene id: 446469:SKED_RS12900
uniprot id: D1BKQ5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

446469:SKED RS00670
gene id: 446469:SKED_RS00670
uniprot id: D1BIS1
names: Similarity
messages: Belongs to the TPP enzyme family.

446469:SKED RS14510
gene id: 446469:SKED_RS14510
uniprot id: D1BBT7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

446469:SKED RS00455
gene id: 446469:SKED_RS00455
uniprot id: D1BI93
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446469:SKED RS18030
gene id: 446469:SKED_RS18030
uniprot id: D1BG37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

446469:SKED RS15310
gene id: 446469:SKED_RS15310
uniprot id: D1BD11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

446469:SKED RS16765
gene id: 446469:SKED_RS16765
uniprot id: D1BEL9
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS05280
gene id: 446469:SKED_RS05280
uniprot id: D1BDG3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

446469:SKED RS03560
gene id: 446469:SKED_RS03560
uniprot id: D1BBC0
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS14540
gene id: 446469:SKED_RS14540
uniprot id: D1BBU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

446469:SKED RS08650
gene id: 446469:SKED_RS08650
uniprot id: D1BGX1
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS03950
gene id: 446469:SKED_RS03950
uniprot id: D1BBY1
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS09800
gene id: 446469:SKED_RS09800
uniprot id: D1BHK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

446469:SKED RS08585
gene id: 446469:SKED_RS08585
uniprot id: D1BGV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

446469:SKED RS08415
gene id: 446469:SKED_RS08415
uniprot id: D1BGR7
names: Similarity
messages: Belongs to the peptidase C56 family.

446469:SKED RS05090
gene id: 446469:SKED_RS05090
uniprot id: D1BCZ2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

446469:SKED RS10170
gene id: 446469:SKED_RS10170
uniprot id: D1BHS7
names: Similarity
messages: Belongs to the TrpC family.

446469:SKED RS13220
gene id: 446469:SKED_RS13220
uniprot id: D1BKX2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS12675
gene id: 446469:SKED_RS12675
uniprot id: D1BKK9
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

446469:SKED RS01370
gene id: 446469:SKED_RS01370
uniprot id: D1BJJ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

446469:SKED RS18575
gene id: 446469:SKED_RS18575
uniprot id: D1BGE2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS17900
gene id: 446469:SKED_RS17900
uniprot id: D1BFM5
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS00320
gene id: 446469:SKED_RS00320
uniprot id: D1BI66
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS06915
gene id: 446469:SKED_RS06915
uniprot id: D1BF51
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

446469:SKED RS04950
gene id: 446469:SKED_RS04950
uniprot id: D1BCW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446469:SKED RS15515
gene id: 446469:SKED_RS15515
uniprot id: D1BD52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

446469:SKED RS02870
gene id: 446469:SKED_RS02870
uniprot id: D1BAJ6
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS16160
gene id: 446469:SKED_RS16160
uniprot id: D1BDW3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

446469:SKED RS02815
gene id: 446469:SKED_RS02815
uniprot id: D1BAI6
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS06550
gene id: 446469:SKED_RS06550
uniprot id: D1BEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

446469:SKED RS03045
gene id: 446469:SKED_RS03045
uniprot id: D1BAN4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

446469:SKED RS10225
gene id: 446469:SKED_RS10225
uniprot id: D1BHT8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

446469:SKED RS12410
gene id: 446469:SKED_RS12410
uniprot id: D1BK23
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS10460
gene id: 446469:SKED_RS10460
uniprot id: D1BHY1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

446469:SKED RS08135
gene id: 446469:SKED_RS08135
uniprot id: D1BGL9
names: Similarity
messages: Belongs to the SufE family.

446469:SKED RS15200
gene id: 446469:SKED_RS15200
uniprot id: D1BCK6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS14330
gene id: 446469:SKED_RS14330
uniprot id: D1BBQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

446469:SKED RS01365
gene id: 446469:SKED_RS01365
uniprot id: D1BJJ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446469:SKED RS16100
gene id: 446469:SKED_RS16100
uniprot id: D1BDV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

446469:SKED RS11985
gene id: 446469:SKED_RS11985
uniprot id: D1BJU6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

446469:SKED RS02085
gene id: 446469:SKED_RS02085
uniprot id: D1BKB6
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS02765
gene id: 446469:SKED_RS02765
uniprot id: D1BAH7
names: Similarity
messages: Belongs to the ice-binding protein family.

446469:SKED RS12705
gene id: 446469:SKED_RS12705
uniprot id: D1BKL5
names: Similarity
messages: Belongs to the peptidase S1C family.

446469:SKED RS07775
gene id: 446469:SKED_RS07775
uniprot id: D1BG12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

446469:SKED RS11110
gene id: 446469:SKED_RS11110
uniprot id: D1BIK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

446469:SKED RS15230
gene id: 446469:SKED_RS15230
uniprot id: D1BCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

446469:SKED RS17880
gene id: 446469:SKED_RS17880
uniprot id: D1BFM1
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS12530
gene id: 446469:SKED_RS12530
uniprot id: D1BK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

446469:SKED RS10955
gene id: 446469:SKED_RS10955
uniprot id: D1BIH0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

446469:SKED RS15250
gene id: 446469:SKED_RS15250
uniprot id: D1BCL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

446469:SKED RS07400
gene id: 446469:SKED_RS07400
uniprot id: D1BFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS06860
gene id: 446469:SKED_RS06860
uniprot id: D1BF42
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

446469:SKED RS03915
gene id: 446469:SKED_RS03915
uniprot id: D1BBX4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS04630
gene id: 446469:SKED_RS04630
uniprot id: D1BCQ0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS18680
gene id: 446469:SKED_RS18680
uniprot id: D1BGG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

446469:SKED RS03625
gene id: 446469:SKED_RS03625
uniprot id: D1BBD3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

446469:SKED RS17215
gene id: 446469:SKED_RS17215
uniprot id: D1BEV7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446469:SKED RS02920
gene id: 446469:SKED_RS02920
uniprot id: D1BAK7
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

446469:SKED RS15340
gene id: 446469:SKED_RS15340
uniprot id: D1BD17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

446469:SKED RS13445
gene id: 446469:SKED_RS13445
uniprot id: D1BAU3
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS04405
gene id: 446469:SKED_RS04405
uniprot id: D1BC72
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

446469:SKED RS03635
gene id: 446469:SKED_RS03635
uniprot id: D1BBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

446469:SKED RS07435
gene id: 446469:SKED_RS07435
uniprot id: D1BFU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

446469:SKED RS08685
gene id: 446469:SKED_RS08685
uniprot id: D1BGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

446469:SKED RS00625
gene id: 446469:SKED_RS00625
uniprot id: D1BIR2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS01195
gene id: 446469:SKED_RS01195
uniprot id: D1BJF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

446469:SKED RS12985
gene id: 446469:SKED_RS12985
uniprot id: D1BKS3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

446469:SKED RS10220
gene id: 446469:SKED_RS10220
uniprot id: D1BHT7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

446469:SKED RS04790
gene id: 446469:SKED_RS04790
uniprot id: D1BCT1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

446469:SKED RS09810
gene id: 446469:SKED_RS09810
uniprot id: D1BHK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

446469:SKED RS07960
gene id: 446469:SKED_RS07960
uniprot id: D1BGI3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

446469:SKED RS18585
gene id: 446469:SKED_RS18585
uniprot id: D1BGE4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

446469:SKED RS02195
gene id: 446469:SKED_RS02195
uniprot id: D1BKD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

446469:SKED RS17350
gene id: 446469:SKED_RS17350
uniprot id: D1BFB8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

446469:SKED RS02460
gene id: 446469:SKED_RS02460
uniprot id: D1BKJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

446469:SKED RS04340
gene id: 446469:SKED_RS04340
uniprot id: D1BC60
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446469:SKED RS12320
gene id: 446469:SKED_RS12320
uniprot id: D1BK05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

446469:SKED RS03270
gene id: 446469:SKED_RS03270
uniprot id: D1BB65
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

446469:SKED RS18540
gene id: 446469:SKED_RS18540
uniprot id: D1BGD5
names: Similarity
messages: Belongs to the peptidase M18 family.

446469:SKED RS03395
gene id: 446469:SKED_RS03395
uniprot id: D1BB87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

446469:SKED RS05455
gene id: 446469:SKED_RS05455
uniprot id: D1BDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

446469:SKED RS05250
gene id: 446469:SKED_RS05250
uniprot id: D1BDF7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS00510
gene id: 446469:SKED_RS00510
uniprot id: D1BIN7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS12825
gene id: 446469:SKED_RS12825
uniprot id: D1BKP0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS09880
gene id: 446469:SKED_RS09880
uniprot id: D1BHM0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

446469:SKED RS11910
gene id: 446469:SKED_RS11910
uniprot id: D1BJE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

446469:SKED RS00420
gene id: 446469:SKED_RS00420
uniprot id: D1BI85
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

446469:SKED RS17105
gene id: 446469:SKED_RS17105
uniprot id: D1BET5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446469:SKED RS16960
gene id: 446469:SKED_RS16960
uniprot id: D1BEQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

446469:SKED RS08060
gene id: 446469:SKED_RS08060
uniprot id: D1BGK4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

446469:SKED RS03190
gene id: 446469:SKED_RS03190
uniprot id: D1BB49
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446469:SKED RS06830
gene id: 446469:SKED_RS06830
uniprot id: D1BF36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446469:SKED RS13335
gene id: 446469:SKED_RS13335
uniprot id: D1BAS2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

446469:SKED RS07475
gene id: 446469:SKED_RS07475
uniprot id: D1BFU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

446469:SKED RS11000
gene id: 446469:SKED_RS11000
uniprot id: D1BIH9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

446469:SKED RS15435
gene id: 446469:SKED_RS15435
uniprot id: D1BD36
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

446469:SKED RS12535
gene id: 446469:SKED_RS12535
uniprot id: D1BK48
names: Similarity
messages: Belongs to the EfeM/EfeO family.

446469:SKED RS11180
gene id: 446469:SKED_RS11180
uniprot id: D1BIL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

446469:SKED RS04005
gene id: 446469:SKED_RS04005
uniprot id: D1BBZ2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

446469:SKED RS18110
gene id: 446469:SKED_RS18110
uniprot id: D1BG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

446469:SKED RS02480
gene id: 446469:SKED_RS02480
uniprot id: D1BKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

446469:SKED RS17070
gene id: 446469:SKED_RS17070
uniprot id: D1BES8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446469:SKED RS15325
gene id: 446469:SKED_RS15325
uniprot id: D1BD14
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

446469:SKED RS07365
gene id: 446469:SKED_RS07365
uniprot id: D1BFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

446469:SKED RS17720
gene id: 446469:SKED_RS17720
uniprot id: D1BFJ0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

446469:SKED RS02800
gene id: 446469:SKED_RS02800
uniprot id: D1BAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11715
gene id: 446469:SKED_RS11715
uniprot id: D1BJA8
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

446469:SKED RS17920
gene id: 446469:SKED_RS17920
uniprot id: D1BFM9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

446469:SKED RS07170
gene id: 446469:SKED_RS07170
uniprot id: D1BFA2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS06480
gene id: 446469:SKED_RS06480
uniprot id: D1BEI4
names: Similarity
messages: Belongs to the DtxR/MntR family.

446469:SKED RS03640
gene id: 446469:SKED_RS03640
uniprot id: D1BBD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446469:SKED RS15715
gene id: 446469:SKED_RS15715
uniprot id: D1BD91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

446469:SKED RS06170
gene id: 446469:SKED_RS06170
uniprot id: D1BEC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

446469:SKED RS04910
gene id: 446469:SKED_RS04910
uniprot id: D1BCV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

446469:SKED RS17305
gene id: 446469:SKED_RS17305
uniprot id: D1BEX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

446469:SKED RS20810
gene id: 446469:SKED_RS20810
uniprot id: D1BFD4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS10775
gene id: 446469:SKED_RS10775
uniprot id: D1BID7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

446469:SKED RS04905
gene id: 446469:SKED_RS04905
uniprot id: D1BCV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

446469:SKED RS01330
gene id: 446469:SKED_RS01330
uniprot id: D1BJI4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS08590
gene id: 446469:SKED_RS08590
uniprot id: D1BGV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

446469:SKED RS02415
gene id: 446469:SKED_RS02415
uniprot id: D1BKI1
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

446469:SKED RS12105
gene id: 446469:SKED_RS12105
uniprot id: D1BJX0
names: Similarity
messages: Belongs to the type IB topoisomerase family.

446469:SKED RS04245
gene id: 446469:SKED_RS04245
uniprot id: D1BC41
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

446469:SKED RS00995
gene id: 446469:SKED_RS00995
uniprot id: D1BIY3
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS11590
gene id: 446469:SKED_RS11590
uniprot id: D1BJ83
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

446469:SKED RS06240
gene id: 446469:SKED_RS06240
uniprot id: D1BED8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

446469:SKED RS06180
gene id: 446469:SKED_RS06180
uniprot id: D1BEC6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS01530
gene id: 446469:SKED_RS01530
uniprot id: D1BJM3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS02335
gene id: 446469:SKED_RS02335
uniprot id: D1BKG4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

446469:SKED RS04490
gene id: 446469:SKED_RS04490
uniprot id: D1BC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11630
gene id: 446469:SKED_RS11630
uniprot id: D1BJ91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

446469:SKED RS12085
gene id: 446469:SKED_RS12085
uniprot id: D1BJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

446469:SKED RS11735
gene id: 446469:SKED_RS11735
uniprot id: D1BJB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

446469:SKED RS02810
gene id: 446469:SKED_RS02810
uniprot id: D1BAI5
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS14535
gene id: 446469:SKED_RS14535
uniprot id: D1BBU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

446469:SKED RS03060
gene id: 446469:SKED_RS03060
uniprot id: D1BAN7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446469:SKED RS12565
gene id: 446469:SKED_RS12565
uniprot id: D1BK54
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446469:SKED RS10335
gene id: 446469:SKED_RS10335
uniprot id: D1BHW0
names: Similarity
messages: Belongs to the peptidase M1 family.

446469:SKED RS13260
gene id: 446469:SKED_RS13260
uniprot id: D1BKY0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS07280
gene id: 446469:SKED_RS07280
uniprot id: D1BFQ9
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS04500
gene id: 446469:SKED_RS04500
uniprot id: D1BC91
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

446469:SKED RS14570
gene id: 446469:SKED_RS14570
uniprot id: D1BBU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

446469:SKED RS16430
gene id: 446469:SKED_RS16430
uniprot id: D1BE19
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS18760
gene id: 446469:SKED_RS18760
uniprot id: D1BIQ3
names: Similarity
messages: Belongs to the barstar family.

446469:SKED RS07565
gene id: 446469:SKED_RS07565
uniprot id: D1BFX0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446469:SKED RS18615
gene id: 446469:SKED_RS18615
uniprot id: D1BGF0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

446469:SKED RS10230
gene id: 446469:SKED_RS10230
uniprot id: D1BHT9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

446469:SKED RS08405
gene id: 446469:SKED_RS08405
uniprot id: D1BGR5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446469:SKED RS00235
gene id: 446469:SKED_RS00235
uniprot id: D1BI50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446469:SKED RS00465
gene id: 446469:SKED_RS00465
uniprot id: D1BI95
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS02280
gene id: 446469:SKED_RS02280
uniprot id: D1BKF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

446469:SKED RS07480
gene id: 446469:SKED_RS07480
uniprot id: D1BFV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS11050
gene id: 446469:SKED_RS11050
uniprot id: D1BIJ0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

446469:SKED RS04710
gene id: 446469:SKED_RS04710
uniprot id: D1BCR6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446469:SKED RS05495
gene id: 446469:SKED_RS05495
uniprot id: D1BDK4
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

446469:SKED RS17935
gene id: 446469:SKED_RS17935
uniprot id: D1BFN2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

446469:SKED RS10320
gene id: 446469:SKED_RS10320
uniprot id: D1BHV7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

446469:SKED RS06820
gene id: 446469:SKED_RS06820
uniprot id: D1BF34
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

446469:SKED RS03410
gene id: 446469:SKED_RS03410
uniprot id: D1BB90
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS00655
gene id: 446469:SKED_RS00655
uniprot id: D1BIR8
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS06260
gene id: 446469:SKED_RS06260
uniprot id: D1BEE2
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS06615
gene id: 446469:SKED_RS06615
uniprot id: D1BEZ3
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS14645
gene id: 446469:SKED_RS14645
uniprot id: D1BC99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

446469:SKED RS16415
gene id: 446469:SKED_RS16415
uniprot id: D1BE16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

446469:SKED RS08860
gene id: 446469:SKED_RS08860
uniprot id: D1BH14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS05725
gene id: 446469:SKED_RS05725
uniprot id: D1BDQ0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

446469:SKED RS13770
gene id: 446469:SKED_RS13770
uniprot id: D1BB08
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

446469:SKED RS13985
gene id: 446469:SKED_RS13985
uniprot id: D1BBI1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.

446469:SKED RS14285
gene id: 446469:SKED_RS14285
uniprot id: D1BBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11310
gene id: 446469:SKED_RS11310
uniprot id: D1BJ26
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS14780
gene id: 446469:SKED_RS14780
uniprot id: D1BCC5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

446469:SKED RS03590
gene id: 446469:SKED_RS03590
uniprot id: D1BBC6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

446469:SKED RS14070
gene id: 446469:SKED_RS14070
uniprot id: D1BBJ8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

446469:SKED RS05485
gene id: 446469:SKED_RS05485
uniprot id: D1BDK2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

446469:SKED RS12605
gene id: 446469:SKED_RS12605
uniprot id: D1BK62
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

446469:SKED RS13245
gene id: 446469:SKED_RS13245
uniprot id: D1BKX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

446469:SKED RS17205
gene id: 446469:SKED_RS17205
uniprot id: D1BEV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

446469:SKED RS00685
gene id: 446469:SKED_RS00685
uniprot id: D1BIS4
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

446469:SKED RS17355
gene id: 446469:SKED_RS17355
uniprot id: D1BFB9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

446469:SKED RS17670
gene id: 446469:SKED_RS17670
uniprot id: D1BFI0
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

446469:SKED RS10790
gene id: 446469:SKED_RS10790
uniprot id: D1BIE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS03245
gene id: 446469:SKED_RS03245
uniprot id: D1BB60
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

446469:SKED RS15725
gene id: 446469:SKED_RS15725
uniprot id: D1BD93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

446469:SKED RS15620
gene id: 446469:SKED_RS15620
uniprot id: D1BD72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS09780
gene id: 446469:SKED_RS09780
uniprot id: D1BHK0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS07660
gene id: 446469:SKED_RS07660
uniprot id: D1BFY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

446469:SKED RS15860
gene id: 446469:SKED_RS15860
uniprot id: D1BDC0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS08815
gene id: 446469:SKED_RS08815
uniprot id: D1BH04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

446469:SKED RS09875
gene id: 446469:SKED_RS09875
uniprot id: D1BHL9
names: Similarity
messages: Belongs to the YciI family.

446469:SKED RS15650
gene id: 446469:SKED_RS15650
uniprot id: D1BD78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

446469:SKED RS08580
gene id: 446469:SKED_RS08580
uniprot id: D1BGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

446469:SKED RS13885
gene id: 446469:SKED_RS13885
uniprot id: D1BB31
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

446469:SKED RS10685
gene id: 446469:SKED_RS10685
uniprot id: D1BIC0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

446469:SKED RS18390
gene id: 446469:SKED_RS18390
uniprot id: D1BGA6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

446469:SKED RS15080
gene id: 446469:SKED_RS15080
uniprot id: D1BCI2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446469:SKED RS05720
gene id: 446469:SKED_RS05720
uniprot id: D1BDP9
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS12960
gene id: 446469:SKED_RS12960
uniprot id: D1BKR8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

446469:SKED RS07670
gene id: 446469:SKED_RS07670
uniprot id: D1BFZ1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

446469:SKED RS08560
gene id: 446469:SKED_RS08560
uniprot id: D1BGV4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446469:SKED RS10235
gene id: 446469:SKED_RS10235
uniprot id: D1BHU0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

446469:SKED RS00310
gene id: 446469:SKED_RS00310
uniprot id: D1BI64
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

446469:SKED RS02255
gene id: 446469:SKED_RS02255
uniprot id: D1BKE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

446469:SKED RS09805
gene id: 446469:SKED_RS09805
uniprot id: D1BHK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

446469:SKED RS01265
gene id: 446469:SKED_RS01265
uniprot id: D1BJH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446469:SKED RS12950
gene id: 446469:SKED_RS12950
uniprot id: D1BKR6
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS03650
gene id: 446469:SKED_RS03650
uniprot id: D1BBD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446469:SKED RS12765
gene id: 446469:SKED_RS12765
uniprot id: D1BKM8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446469:SKED RS01175
gene id: 446469:SKED_RS01175
uniprot id: D1BJF3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446469:SKED RS08840
gene id: 446469:SKED_RS08840
uniprot id: D1BH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

446469:SKED RS15175
gene id: 446469:SKED_RS15175
uniprot id: D1BCK1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

446469:SKED RS15130
gene id: 446469:SKED_RS15130
uniprot id: D1BCJ2
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

446469:SKED RS01455
gene id: 446469:SKED_RS01455
uniprot id: D1BJK9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

446469:SKED RS06575
gene id: 446469:SKED_RS06575
uniprot id: D1BEY5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446469:SKED RS11695
gene id: 446469:SKED_RS11695
uniprot id: D1BJA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

446469:SKED RS01875
gene id: 446469:SKED_RS01875
uniprot id: D1BK74
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS03330
gene id: 446469:SKED_RS03330
uniprot id: D1BB77
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

446469:SKED RS10150
gene id: 446469:SKED_RS10150
uniprot id: D1BHS3
names: Similarity
messages: Belongs to the glutamate synthase family.

446469:SKED RS08620
gene id: 446469:SKED_RS08620
uniprot id: D1BGW5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

446469:SKED RS16865
gene id: 446469:SKED_RS16865
uniprot id: D1BEN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446469:SKED RS13475
gene id: 446469:SKED_RS13475
uniprot id: D1BAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

446469:SKED RS11190
gene id: 446469:SKED_RS11190
uniprot id: D1BIL9
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS14520
gene id: 446469:SKED_RS14520
uniprot id: D1BBT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

446469:SKED RS07720
gene id: 446469:SKED_RS07720
uniprot id: D1BG01
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS10870
gene id: 446469:SKED_RS10870
uniprot id: D1BIF7
names: Similarity
messages: Belongs to the TlyA family.

446469:SKED RS13840
gene id: 446469:SKED_RS13840
uniprot id: D1BB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

446469:SKED RS13965
gene id: 446469:SKED_RS13965
uniprot id: D1BBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

446469:SKED RS00070
gene id: 446469:SKED_RS00070
uniprot id: D1BI18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

446469:SKED RS15260
gene id: 446469:SKED_RS15260
uniprot id: D1BCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

446469:SKED RS12515
gene id: 446469:SKED_RS12515
uniprot id: D1BK44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

446469:SKED RS05220
gene id: 446469:SKED_RS05220
uniprot id: D1BDF1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

446469:SKED RS05440
gene id: 446469:SKED_RS05440
uniprot id: D1BDJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

446469:SKED RS14475
gene id: 446469:SKED_RS14475
uniprot id: D1BBT0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

446469:SKED RS11645
gene id: 446469:SKED_RS11645
uniprot id: D1BJ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

446469:SKED RS14710
gene id: 446469:SKED_RS14710
uniprot id: D1BCB1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

446469:SKED RS14640
gene id: 446469:SKED_RS14640
uniprot id: D1BC98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446469:SKED RS16475
gene id: 446469:SKED_RS16475
uniprot id: D1BE28
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS10385
gene id: 446469:SKED_RS10385
uniprot id: D1BHW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446469:SKED RS14655
gene id: 446469:SKED_RS14655
uniprot id: D1BCA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

446469:SKED RS18235
gene id: 446469:SKED_RS18235
uniprot id: D1BG78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

446469:SKED RS12630
gene id: 446469:SKED_RS12630
uniprot id: D1BKK0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS10160
gene id: 446469:SKED_RS10160
uniprot id: D1BHS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

446469:SKED RS16480
gene id: 446469:SKED_RS16480
uniprot id: D1BE29
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

446469:SKED RS10415
gene id: 446469:SKED_RS10415
uniprot id: D1BHX4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446469:SKED RS01905
gene id: 446469:SKED_RS01905
uniprot id: D1BK80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS06510
gene id: 446469:SKED_RS06510
uniprot id: D1BEJ0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS08805
gene id: 446469:SKED_RS08805
uniprot id: D1BH02
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

446469:SKED RS15305
gene id: 446469:SKED_RS15305
uniprot id: D1BD10
names: Similarity
messages: Belongs to the peptidase C40 family.

446469:SKED RS14500
gene id: 446469:SKED_RS14500
uniprot id: D1BBT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

446469:SKED RS05475
gene id: 446469:SKED_RS05475
uniprot id: D1BDK0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

446469:SKED RS12835
gene id: 446469:SKED_RS12835
uniprot id: D1BKP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS15680
gene id: 446469:SKED_RS15680
uniprot id: D1BD84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

446469:SKED RS14395
gene id: 446469:SKED_RS14395
uniprot id: D1BBR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

446469:SKED RS14615
gene id: 446469:SKED_RS14615
uniprot id: D1BC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

446469:SKED RS02065
gene id: 446469:SKED_RS02065
uniprot id: D1BKB1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446469:SKED RS17045
gene id: 446469:SKED_RS17045
uniprot id: D1BES2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446469:SKED RS15335
gene id: 446469:SKED_RS15335
uniprot id: D1BD16
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

446469:SKED RS12990
gene id: 446469:SKED_RS12990
uniprot id: D1BKS4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

446469:SKED RS10075
gene id: 446469:SKED_RS10075
uniprot id: D1BHQ7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS00755
gene id: 446469:SKED_RS00755
uniprot id: D1BIT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446469:SKED RS05980
gene id: 446469:SKED_RS05980
uniprot id: D1BE84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS12645
gene id: 446469:SKED_RS12645
uniprot id: D1BKK3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

446469:SKED RS11280
gene id: 446469:SKED_RS11280
uniprot id: D1BJ20
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

446469:SKED RS00970
gene id: 446469:SKED_RS00970
uniprot id: D1BIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

446469:SKED RS14375
gene id: 446469:SKED_RS14375
uniprot id: D1BBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

446469:SKED RS10720
gene id: 446469:SKED_RS10720
uniprot id: D1BIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

446469:SKED RS12975
gene id: 446469:SKED_RS12975
uniprot id: D1BKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

446469:SKED RS09910
gene id: 446469:SKED_RS09910
uniprot id: D1BHM6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

446469:SKED RS11580
gene id: 446469:SKED_RS11580
uniprot id: D1BJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

446469:SKED RS15115
gene id: 446469:SKED_RS15115
uniprot id: D1BCI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS02565
gene id: 446469:SKED_RS02565
uniprot id: D1BAD6
names: Similarity
messages: Belongs to the UxaA family.

446469:SKED RS14685
gene id: 446469:SKED_RS14685
uniprot id: D1BCA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS03325
gene id: 446469:SKED_RS03325
uniprot id: D1BB76
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

446469:SKED RS04840
gene id: 446469:SKED_RS04840
uniprot id: D1BCU1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS17430
gene id: 446469:SKED_RS17430
uniprot id: D1BFD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS12340
gene id: 446469:SKED_RS12340
uniprot id: D1BK09
names: Similarity
messages: Belongs to the peptidase S8 family.

446469:SKED RS14565
gene id: 446469:SKED_RS14565
uniprot id: D1BBU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

446469:SKED RS05685
gene id: 446469:SKED_RS05685
uniprot id: D1BDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS14595
gene id: 446469:SKED_RS14595
uniprot id: D1BBV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

446469:SKED RS03745
gene id: 446469:SKED_RS03745
uniprot id: D1BBF5
names: Similarity
messages: Belongs to the UPF0336 family.

446469:SKED RS13660
gene id: 446469:SKED_RS13660
uniprot id: D1BAY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

446469:SKED RS08910
gene id: 446469:SKED_RS08910
uniprot id: D1BH24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

446469:SKED RS00415
gene id: 446469:SKED_RS00415
uniprot id: D1BI84
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446469:SKED RS11320
gene id: 446469:SKED_RS11320
uniprot id: D1BJ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

446469:SKED RS09215
gene id: 446469:SKED_RS09215
uniprot id: D1BH83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS10185
gene id: 446469:SKED_RS10185
uniprot id: D1BHT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

446469:SKED RS04955
gene id: 446469:SKED_RS04955
uniprot id: D1BCW4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

446469:SKED RS02885
gene id: 446469:SKED_RS02885
uniprot id: D1BAJ9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

446469:SKED RS00730
gene id: 446469:SKED_RS00730
uniprot id: D1BIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

446469:SKED RS17260
gene id: 446469:SKED_RS17260
uniprot id: D1BEW7
names: Similarity
messages: Belongs to the GARS family.

446469:SKED RS10290
gene id: 446469:SKED_RS10290
uniprot id: D1BHV1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

446469:SKED RS03295
gene id: 446469:SKED_RS03295
uniprot id: D1BB70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

446469:SKED RS11570
gene id: 446469:SKED_RS11570
uniprot id: D1BJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

446469:SKED RS14490
gene id: 446469:SKED_RS14490
uniprot id: D1BBT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446469:SKED RS03385
gene id: 446469:SKED_RS03385
uniprot id: D1BB85
names: Similarity
messages: Belongs to the ribulokinase family.

446469:SKED RS06910
gene id: 446469:SKED_RS06910
uniprot id: D1BF50
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

446469:SKED RS16805
gene id: 446469:SKED_RS16805
uniprot id: D1BEM7
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

446469:SKED RS09860
gene id: 446469:SKED_RS09860
uniprot id: D1BHL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

446469:SKED RS07680
gene id: 446469:SKED_RS07680
uniprot id: D1BFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

446469:SKED RS15330
gene id: 446469:SKED_RS15330
uniprot id: D1BD15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

446469:SKED RS03290
gene id: 446469:SKED_RS03290
uniprot id: D1BB69
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS00060
gene id: 446469:SKED_RS00060
uniprot id: D1BI16
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

446469:SKED RS11635
gene id: 446469:SKED_RS11635
uniprot id: D1BJ92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

446469:SKED RS13460
gene id: 446469:SKED_RS13460
uniprot id: D1BAU6
names: Similarity
messages: Belongs to the peptidase S9C family.

446469:SKED RS10155
gene id: 446469:SKED_RS10155
uniprot id: D1BHS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

446469:SKED RS16930
gene id: 446469:SKED_RS16930
uniprot id: D1BEQ0
names: Similarity
messages: Belongs to the peptidase M20A family.

446469:SKED RS18670
gene id: 446469:SKED_RS18670
uniprot id: D1BGG1
names: Similarity
messages: Belongs to the thioredoxin family.

446469:SKED RS15245
gene id: 446469:SKED_RS15245
uniprot id: D1BCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

446469:SKED RS16740
gene id: 446469:SKED_RS16740
uniprot id: D1BEL4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

446469:SKED RS07880
gene id: 446469:SKED_RS07880
uniprot id: D1BGG7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

446469:SKED RS07180
gene id: 446469:SKED_RS07180
uniprot id: D1BFA4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

446469:SKED RS14505
gene id: 446469:SKED_RS14505
uniprot id: D1BBT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

446469:SKED RS07265
gene id: 446469:SKED_RS07265
uniprot id: D1BFQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS17750
gene id: 446469:SKED_RS17750
uniprot id: D1BFJ6
names: Similarity
messages: Belongs to the CsoR family.

446469:SKED RS05595
gene id: 446469:SKED_RS05595
uniprot id: D1BDM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

446469:SKED RS11950
gene id: 446469:SKED_RS11950
uniprot id: D1BJU1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

446469:SKED RS15120
gene id: 446469:SKED_RS15120
uniprot id: D1BCJ0
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS18595
gene id: 446469:SKED_RS18595
uniprot id: D1BGE6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS06440
gene id: 446469:SKED_RS06440
uniprot id: D1BEH6
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

446469:SKED RS15290
gene id: 446469:SKED_RS15290
uniprot id: D1BCM4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

446469:SKED RS07760
gene id: 446469:SKED_RS07760
uniprot id: D1BG09
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

446469:SKED RS05045
gene id: 446469:SKED_RS05045
uniprot id: D1BCY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

446469:SKED RS03665
gene id: 446469:SKED_RS03665
uniprot id: D1BBE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446469:SKED RS08800
gene id: 446469:SKED_RS08800
uniprot id: D1BH01
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS18590
gene id: 446469:SKED_RS18590
uniprot id: D1BGE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

446469:SKED RS03120
gene id: 446469:SKED_RS03120
uniprot id: D1BAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS14630
gene id: 446469:SKED_RS14630
uniprot id: D1BC96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

446469:SKED RS15595
gene id: 446469:SKED_RS15595
uniprot id: D1BD67
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

446469:SKED RS08000
gene id: 446469:SKED_RS08000
uniprot id: D1BGJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS01510
gene id: 446469:SKED_RS01510
uniprot id: D1BJL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS13990
gene id: 446469:SKED_RS13990
uniprot id: D1BBI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

446469:SKED RS14580
gene id: 446469:SKED_RS14580
uniprot id: D1BBV1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

446469:SKED RS13345
gene id: 446469:SKED_RS13345
uniprot id: D1BAS4
names: Similarity
messages: Belongs to the universal stress protein A family.

446469:SKED RS07350
gene id: 446469:SKED_RS07350
uniprot id: D1BFS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

446469:SKED RS03265
gene id: 446469:SKED_RS03265
uniprot id: D1BB64
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

446469:SKED RS16340
gene id: 446469:SKED_RS16340
uniprot id: D1BE01
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

446469:SKED RS15790
gene id: 446469:SKED_RS15790
uniprot id: D1BDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

446469:SKED RS04685
gene id: 446469:SKED_RS04685
uniprot id: D1BCR1
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS08690
gene id: 446469:SKED_RS08690
uniprot id: D1BGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

446469:SKED RS02080
gene id: 446469:SKED_RS02080
uniprot id: D1BKB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

446469:SKED RS00615
gene id: 446469:SKED_RS00615
uniprot id: D1BIQ9
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS15900
gene id: 446469:SKED_RS15900
uniprot id: D1BDC8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS08385
gene id: 446469:SKED_RS08385
uniprot id: D1BGR1
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS01180
gene id: 446469:SKED_RS01180
uniprot id: D1BJF4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS02955
gene id: 446469:SKED_RS02955
uniprot id: D1BAL4
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

446469:SKED RS04120
gene id: 446469:SKED_RS04120
uniprot id: D1BC16
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446469:SKED RS11825
gene id: 446469:SKED_RS11825
uniprot id: D1BJD0
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

446469:SKED RS00220
gene id: 446469:SKED_RS00220
uniprot id: D1BI47
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446469:SKED RS11690
gene id: 446469:SKED_RS11690
uniprot id: D1BJA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

446469:SKED RS13815
gene id: 446469:SKED_RS13815
uniprot id: D1BB17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

446469:SKED RS05230
gene id: 446469:SKED_RS05230
uniprot id: D1BDF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

446469:SKED RS12620
gene id: 446469:SKED_RS12620
uniprot id: D1BKJ8
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

446469:SKED RS08825
gene id: 446469:SKED_RS08825
uniprot id: D1BH06
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

446469:SKED RS11155
gene id: 446469:SKED_RS11155
uniprot id: D1BIL2
names: Similarity
messages: Belongs to the YggT family.

446469:SKED RS12325
gene id: 446469:SKED_RS12325
uniprot id: D1BK06
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

446469:SKED RS11885
gene id: 446469:SKED_RS11885
uniprot id: D1BJE2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446469:SKED RS00245
gene id: 446469:SKED_RS00245
uniprot id: D1BI51
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446469:SKED RS05740
gene id: 446469:SKED_RS05740
uniprot id: D1BDQ3
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

446469:SKED RS14405
gene id: 446469:SKED_RS14405
uniprot id: D1BBR6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

446469:SKED RS18320
gene id: 446469:SKED_RS18320
uniprot id: D1BG92
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446469:SKED RS17835
gene id: 446469:SKED_RS17835
uniprot id: D1BFL2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

446469:SKED RS03080
gene id: 446469:SKED_RS03080
uniprot id: D1BAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS11620
gene id: 446469:SKED_RS11620
uniprot id: D1BJ89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

446469:SKED RS18000
gene id: 446469:SKED_RS18000
uniprot id: D1BFP5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS08940
gene id: 446469:SKED_RS08940
uniprot id: D1BH30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

446469:SKED RS15100
gene id: 446469:SKED_RS15100
uniprot id: D1BCI6
names: Similarity
messages: Belongs to the universal stress protein A family.

446469:SKED RS07955
gene id: 446469:SKED_RS07955
uniprot id: D1BGI2
names: Subcellular Location Annotation
messages: Cell membrane

446469:SKED RS07995
gene id: 446469:SKED_RS07995
uniprot id: D1BGJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

446469:SKED RS03025
gene id: 446469:SKED_RS03025
uniprot id: D1BAM9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

446469:SKED RS18115
gene id: 446469:SKED_RS18115
uniprot id: D1BG54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS11065
gene id: 446469:SKED_RS11065
uniprot id: D1BIJ3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

446469:SKED RS01745
gene id: 446469:SKED_RS01745
uniprot id: D1BJR7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

446469:SKED RS00305
gene id: 446469:SKED_RS00305
uniprot id: D1BI63
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

446469:SKED RS10800
gene id: 446469:SKED_RS10800
uniprot id: D1BIE3
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

446469:SKED RS16510
gene id: 446469:SKED_RS16510
uniprot id: D1BE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

446469:SKED RS12025
gene id: 446469:SKED_RS12025
uniprot id: D1BJV4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

446469:SKED RS11560
gene id: 446469:SKED_RS11560
uniprot id: D1BJ77
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

446469:SKED RS09490
gene id: 446469:SKED_RS09490
uniprot id: D1BHE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS06490
gene id: 446469:SKED_RS06490
uniprot id: D1BEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

446469:SKED RS12370
gene id: 446469:SKED_RS12370
uniprot id: D1BK15
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

446469:SKED RS07410
gene id: 446469:SKED_RS07410
uniprot id: D1BFT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

446469:SKED RS12755
gene id: 446469:SKED_RS12755
uniprot id: D1BKM6
names: Similarity
messages: Belongs to the citrate synthase family.

446469:SKED RS03315
gene id: 446469:SKED_RS03315
uniprot id: D1BB74
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS14660
gene id: 446469:SKED_RS14660
uniprot id: D1BCA2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

446469:SKED RS18710
gene id: 446469:SKED_RS18710
uniprot id: D1BGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

446469:SKED RS18665
gene id: 446469:SKED_RS18665
uniprot id: D1BGG0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

446469:SKED RS05775
gene id: 446469:SKED_RS05775
uniprot id: D1BDR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

446469:SKED RS10280
gene id: 446469:SKED_RS10280
uniprot id: D1BHU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

446469:SKED RS06255
gene id: 446469:SKED_RS06255
uniprot id: D1BEE1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

446469:SKED RS17610
gene id: 446469:SKED_RS17610
uniprot id: D1BFG8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446469:SKED RS12310
gene id: 446469:SKED_RS12310
uniprot id: D1BK03
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

446469:SKED RS06275
gene id: 446469:SKED_RS06275
uniprot id: D1BEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

446469:SKED RS16165
gene id: 446469:SKED_RS16165
uniprot id: D1BDW4
names: Similarity
messages: Belongs to the glycosyl hydrolase.

446469:SKED RS05130
gene id: 446469:SKED_RS05130
uniprot id: D1BD00
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS02315
gene id: 446469:SKED_RS02315
uniprot id: D1BKG0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS13405
gene id: 446469:SKED_RS13405
uniprot id: D1BAT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS13420
gene id: 446469:SKED_RS13420
uniprot id: D1BAT9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446469:SKED RS12655
gene id: 446469:SKED_RS12655
uniprot id: D1BKK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446469:SKED RS00905
gene id: 446469:SKED_RS00905
uniprot id: D1BIW6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS03820
gene id: 446469:SKED_RS03820
uniprot id: D1BBH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

446469:SKED RS06590
gene id: 446469:SKED_RS06590
uniprot id: D1BEY8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

446469:SKED RS06930
gene id: 446469:SKED_RS06930
uniprot id: D1BF54
names: Similarity
messages: Belongs to the CdaR family.

446469:SKED RS14600
gene id: 446469:SKED_RS14600
uniprot id: D1BBV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

446469:SKED RS06380
gene id: 446469:SKED_RS06380
uniprot id: D1BEG5
names: Similarity
messages: Belongs to the MQO family.

446469:SKED RS06610
gene id: 446469:SKED_RS06610
uniprot id: D1BEZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

446469:SKED RS04265
gene id: 446469:SKED_RS04265
uniprot id: D1BC45
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

446469:SKED RS04415
gene id: 446469:SKED_RS04415
uniprot id: D1BC74
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

446469:SKED RS03065
gene id: 446469:SKED_RS03065
uniprot id: D1BAN8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

446469:SKED RS14900
gene id: 446469:SKED_RS14900
uniprot id: D1BCE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446469:SKED RS04900
gene id: 446469:SKED_RS04900
uniprot id: D1BCV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

446469:SKED RS14290
gene id: 446469:SKED_RS14290
uniprot id: D1BBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS03995
gene id: 446469:SKED_RS03995
uniprot id: D1BBZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

446469:SKED RS02455
gene id: 446469:SKED_RS02455
uniprot id: D1BKI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

446469:SKED RS03160
gene id: 446469:SKED_RS03160
uniprot id: D1BAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446469:SKED RS03575
gene id: 446469:SKED_RS03575
uniprot id: D1BBC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

446469:SKED RS05885
gene id: 446469:SKED_RS05885
uniprot id: D1BE66
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

446469:SKED RS00935
gene id: 446469:SKED_RS00935
uniprot id: D1BIX2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

446469:SKED RS11515
gene id: 446469:SKED_RS11515
uniprot id: D1BJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

446469:SKED RS04975
gene id: 446469:SKED_RS04975
uniprot id: D1BCW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

446469:SKED RS01165
gene id: 446469:SKED_RS01165
uniprot id: D1BJF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

446469:SKED RS10165
gene id: 446469:SKED_RS10165
uniprot id: D1BHS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

446469:SKED RS07095
gene id: 446469:SKED_RS07095
uniprot id: D1BF86
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS08870
gene id: 446469:SKED_RS08870
uniprot id: D1BH16
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

446469:SKED RS10550
gene id: 446469:SKED_RS10550
uniprot id: D1BHZ9
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

446469:SKED RS01910
gene id: 446469:SKED_RS01910
uniprot id: D1BK81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS15365
gene id: 446469:SKED_RS15365
uniprot id: D1BD22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

446469:SKED RS13210
gene id: 446469:SKED_RS13210
uniprot id: D1BKX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446469:SKED RS14410
gene id: 446469:SKED_RS14410
uniprot id: D1BBR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

446469:SKED RS13700
gene id: 446469:SKED_RS13700
uniprot id: D1BAZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

446469:SKED RS11520
gene id: 446469:SKED_RS11520
uniprot id: D1BJ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

446469:SKED RS07605
gene id: 446469:SKED_RS07605
uniprot id: D1BFX8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

446469:SKED RS09140
gene id: 446469:SKED_RS09140
uniprot id: D1BH69
names: Similarity
messages: Belongs to the Dps family.

446469:SKED RS08855
gene id: 446469:SKED_RS08855
uniprot id: D1BH13
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS06130
gene id: 446469:SKED_RS06130
uniprot id: D1BEB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446469:SKED RS02205
gene id: 446469:SKED_RS02205
uniprot id: D1BKE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446469:SKED RS11185
gene id: 446469:SKED_RS11185
uniprot id: D1BIL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS12035
gene id: 446469:SKED_RS12035
uniprot id: D1BJV6
names: Similarity
messages: Belongs to the peptidase M13 family.

446469:SKED RS03700
gene id: 446469:SKED_RS03700
uniprot id: D1BBE8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

446469:SKED RS07540
gene id: 446469:SKED_RS07540
uniprot id: D1BFW5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

446469:SKED RS08850
gene id: 446469:SKED_RS08850
uniprot id: D1BH12
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS12615
gene id: 446469:SKED_RS12615
uniprot id: D1BKJ7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS08810
gene id: 446469:SKED_RS08810
uniprot id: D1BH03
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

446469:SKED RS07010
gene id: 446469:SKED_RS07010
uniprot id: D1BF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS00125
gene id: 446469:SKED_RS00125
uniprot id: D1BI28
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

446469:SKED RS10580
gene id: 446469:SKED_RS10580
uniprot id: D1BI05
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS14790
gene id: 446469:SKED_RS14790
uniprot id: D1BCC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

446469:SKED RS02685
gene id: 446469:SKED_RS02685
uniprot id: D1BAG0
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

446469:SKED RS12945
gene id: 446469:SKED_RS12945
uniprot id: D1BKR5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

446469:SKED RS07690
gene id: 446469:SKED_RS07690
uniprot id: D1BFZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

446469:SKED RS04980
gene id: 446469:SKED_RS04980
uniprot id: D1BCW9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

446469:SKED RS11005
gene id: 446469:SKED_RS11005
uniprot id: D1BII0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

446469:SKED RS05335
gene id: 446469:SKED_RS05335
uniprot id: D1BDH4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

446469:SKED RS18055
gene id: 446469:SKED_RS18055
uniprot id: D1BG42
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS02155
gene id: 446469:SKED_RS02155
uniprot id: D1BKD0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

446469:SKED RS04625
gene id: 446469:SKED_RS04625
uniprot id: D1BCP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446469:SKED RS00005
gene id: 446469:SKED_RS00005
uniprot id: D1BI06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

446469:SKED RS17925
gene id: 446469:SKED_RS17925
uniprot id: D1BFN0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

446469:SKED RS01675
gene id: 446469:SKED_RS01675
uniprot id: D1BJQ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

446469:SKED RS13790
gene id: 446469:SKED_RS13790
uniprot id: D1BB12
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

446469:SKED RS11370
gene id: 446469:SKED_RS11370
uniprot id: D1BJ38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

446469:SKED RS04895
gene id: 446469:SKED_RS04895
uniprot id: D1BCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

446469:SKED RS06585
gene id: 446469:SKED_RS06585
uniprot id: D1BEY7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

446469:SKED RS17380
gene id: 446469:SKED_RS17380
uniprot id: D1BFC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

446469:SKED RS07470
gene id: 446469:SKED_RS07470
uniprot id: D1BFU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446469:SKED RS15105
gene id: 446469:SKED_RS15105
uniprot id: D1BCI7
names: Similarity
messages: Belongs to the peptidase C40 family.

446469:SKED RS04160
gene id: 446469:SKED_RS04160
uniprot id: D1BC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

446469:SKED RS06725
gene id: 446469:SKED_RS06725
uniprot id: D1BF15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS03055
gene id: 446469:SKED_RS03055
uniprot id: D1BAN6
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS13995
gene id: 446469:SKED_RS13995
uniprot id: D1BBI3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

446469:SKED RS14430
gene id: 446469:SKED_RS14430
uniprot id: D1BBS1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS06245
gene id: 446469:SKED_RS06245
uniprot id: D1BED9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

446469:SKED RS10060
gene id: 446469:SKED_RS10060
uniprot id: D1BHQ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446469:SKED RS17460
gene id: 446469:SKED_RS17460
uniprot id: D1BFD8
names: Similarity
messages: Belongs to the pirin family.

446469:SKED RS04030
gene id: 446469:SKED_RS04030
uniprot id: D1BBZ7
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS01515
gene id: 446469:SKED_RS01515
uniprot id: D1BJM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS18270
gene id: 446469:SKED_RS18270
uniprot id: D1BG82
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

446469:SKED RS05535
gene id: 446469:SKED_RS05535
uniprot id: D1BDL2
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

446469:SKED RS05610
gene id: 446469:SKED_RS05610
uniprot id: D1BDM8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

446469:SKED RS11295
gene id: 446469:SKED_RS11295
uniprot id: D1BJ23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

446469:SKED RS18395
gene id: 446469:SKED_RS18395
uniprot id: D1BGA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

446469:SKED RS17530
gene id: 446469:SKED_RS17530
uniprot id: D1BFF2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446469:SKED RS09460
gene id: 446469:SKED_RS09460
uniprot id: D1BHD4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446469:SKED RS08830
gene id: 446469:SKED_RS08830
uniprot id: D1BH07
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS10915
gene id: 446469:SKED_RS10915
uniprot id: D1BIG2
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

446469:SKED RS19120
gene id: 446469:SKED_RS19120
uniprot id: D1BB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

446469:SKED RS08090
gene id: 446469:SKED_RS08090
uniprot id: D1BGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446469:SKED RS01160
gene id: 446469:SKED_RS01160
uniprot id: D1BJF0
names: Similarity
messages: Belongs to the peptidase S51 family.

446469:SKED RS16145
gene id: 446469:SKED_RS16145
uniprot id: D1BDW0
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

446469:SKED RS11445
gene id: 446469:SKED_RS11445
uniprot id: D1BJ53
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446469:SKED RS11660
gene id: 446469:SKED_RS11660
uniprot id: D1BJ97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

446469:SKED RS10035
gene id: 446469:SKED_RS10035
uniprot id: D1BHP9
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446469:SKED RS08025
gene id: 446469:SKED_RS08025
uniprot id: D1BGJ6
names: Similarity
messages: Belongs to the FemABX family.

446469:SKED RS11400
gene id: 446469:SKED_RS11400
uniprot id: D1BJ44
names: Similarity
messages: Belongs to the FPG family.

446469:SKED RS09760
gene id: 446469:SKED_RS09760
uniprot id: D1BHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

446469:SKED RS08700
gene id: 446469:SKED_RS08700
uniprot id: D1BGY1
names: Similarity
messages: Belongs to the GSP E family.

446469:SKED RS15090
gene id: 446469:SKED_RS15090
uniprot id: D1BCI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446469:SKED RS16735
gene id: 446469:SKED_RS16735
uniprot id: D1BEL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

446469:SKED RS00315
gene id: 446469:SKED_RS00315
uniprot id: D1BI65
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS10980
gene id: 446469:SKED_RS10980
uniprot id: D1BIH5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

446469:SKED RS15195
gene id: 446469:SKED_RS15195
uniprot id: D1BCK5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446469:SKED RS10805
gene id: 446469:SKED_RS10805
uniprot id: D1BIE4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446469:SKED RS14415
gene id: 446469:SKED_RS14415
uniprot id: D1BBR8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

446469:SKED RS08020
gene id: 446469:SKED_RS08020
uniprot id: D1BGJ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446469:SKED RS00450
gene id: 446469:SKED_RS00450
uniprot id: D1BI92
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

446469:SKED RS04095
gene id: 446469:SKED_RS04095
uniprot id: D1BC11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS09710
gene id: 446469:SKED_RS09710
uniprot id: D1BHI6
names: Similarity
messages: Belongs to the UDPGP type 1 family.

446469:SKED RS18620
gene id: 446469:SKED_RS18620
uniprot id: D1BGF1
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS14740
gene id: 446469:SKED_RS14740
uniprot id: D1BCB7
names: Subcellular Location Annotation
messages: Cell membrane

446469:SKED RS04830
gene id: 446469:SKED_RS04830
uniprot id: D1BCT9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

446469:SKED RS03815
gene id: 446469:SKED_RS03815
uniprot id: D1BBG9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

446469:SKED RS12200
gene id: 446469:SKED_RS12200
uniprot id: D1BJY4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446469:SKED RS05200
gene id: 446469:SKED_RS05200
uniprot id: D1BDE7
names: Similarity
messages: Belongs to the DNA photolyase family.

446469:SKED RS14635
gene id: 446469:SKED_RS14635
uniprot id: D1BC97
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446469:SKED RS07895
gene id: 446469:SKED_RS07895
uniprot id: D1BGH0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

446469:SKED RS02290
gene id: 446469:SKED_RS02290
uniprot id: D1BKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446469:SKED RS10010
gene id: 446469:SKED_RS10010
uniprot id: D1BHP4
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS14705
gene id: 446469:SKED_RS14705
uniprot id: D1BCB0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

446469:SKED RS10940
gene id: 446469:SKED_RS10940
uniprot id: D1BIG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446469:SKED RS14350
gene id: 446469:SKED_RS14350
uniprot id: D1BBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

446469:SKED RS11585
gene id: 446469:SKED_RS11585
uniprot id: D1BJ82
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

446469:SKED RS04325
gene id: 446469:SKED_RS04325
uniprot id: D1BC57
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

446469:SKED RS14930
gene id: 446469:SKED_RS14930
uniprot id: D1BCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

446469:SKED RS14555
gene id: 446469:SKED_RS14555
uniprot id: D1BBU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

446469:SKED RS05575
gene id: 446469:SKED_RS05575
uniprot id: D1BDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

446469:SKED RS04810
gene id: 446469:SKED_RS04810
uniprot id: D1BCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446469:SKED RS12360
gene id: 446469:SKED_RS12360
uniprot id: D1BK13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

446469:SKED RS07025
gene id: 446469:SKED_RS07025
uniprot id: D1BF72
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

446469:SKED RS07070
gene id: 446469:SKED_RS07070
uniprot id: D1BF81
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS03660
gene id: 446469:SKED_RS03660
uniprot id: D1BBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

446469:SKED RS16170
gene id: 446469:SKED_RS16170
uniprot id: D1BDW5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446469:SKED RS15110
gene id: 446469:SKED_RS15110
uniprot id: D1BCI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

446469:SKED RS07240
gene id: 446469:SKED_RS07240
uniprot id: D1BFQ1
names: Subcellular Location Annotation
messages: Membrane

446469:SKED RS04525
gene id: 446469:SKED_RS04525
uniprot id: D1BCM8
names: Subcellular Location Annotation
messages: Membrane