446465:BFAE RS09700
gene id: 446465:BFAE_RS09700
uniprot id: C7MDW6
names: Similarity
messages: Belongs to the FPG family.

446465:BFAE RS04015
gene id: 446465:BFAE_RS04015
uniprot id: C7M9X7
names: Similarity
messages: Belongs to the hyi family.

446465:BFAE RS10070
gene id: 446465:BFAE_RS10070
uniprot id: C7ME33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

446465:BFAE RS00760
gene id: 446465:BFAE_RS00760
uniprot id: C7MFR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS12400
gene id: 446465:BFAE_RS12400
uniprot id: C7MG51
names: Similarity
messages: Belongs to the Fur family.

446465:BFAE RS07400
gene id: 446465:BFAE_RS07400
uniprot id: C7MCM1
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

446465:BFAE RS01920
gene id: 446465:BFAE_RS01920
uniprot id: C7MGS4
names: Similarity
messages: Belongs to the peptidase C40 family.

446465:BFAE RS09925
gene id: 446465:BFAE_RS09925
uniprot id: C7ME05
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

446465:BFAE RS07000
gene id: 446465:BFAE_RS07000
uniprot id: C7MCE2
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

446465:BFAE RS15250
gene id: 446465:BFAE_RS15250
uniprot id: C7MAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS08195
gene id: 446465:BFAE_RS08195
uniprot id: C7MD26
names: Similarity
messages: Belongs to the glutamine synthetase family.

446465:BFAE RS04045
gene id: 446465:BFAE_RS04045
uniprot id: C7M9Y3
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

446465:BFAE RS09455
gene id: 446465:BFAE_RS09455
uniprot id: C7MDR9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

446465:BFAE RS06570
gene id: 446465:BFAE_RS06570
uniprot id: C7MC66
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

446465:BFAE RS14895
gene id: 446465:BFAE_RS14895
uniprot id: C7MA94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS08285
gene id: 446465:BFAE_RS08285
uniprot id: C7MD42
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

446465:BFAE RS03110
gene id: 446465:BFAE_RS03110
uniprot id: C7MI71
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS10580
gene id: 446465:BFAE_RS10580
uniprot id: C7MED5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

446465:BFAE RS05565
gene id: 446465:BFAE_RS05565
uniprot id: C7MBL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

446465:BFAE RS00500
gene id: 446465:BFAE_RS00500
uniprot id: C7MF84
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS05860
gene id: 446465:BFAE_RS05860
uniprot id: C7MBS6
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

446465:BFAE RS07325
gene id: 446465:BFAE_RS07325
uniprot id: C7MCK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

446465:BFAE RS14855
gene id: 446465:BFAE_RS14855
uniprot id: C7MA86
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

446465:BFAE RS14470
gene id: 446465:BFAE_RS14470
uniprot id: C7MA09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS11530
gene id: 446465:BFAE_RS11530
uniprot id: C7MEW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS09285
gene id: 446465:BFAE_RS09285
uniprot id: C7MDN5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

446465:BFAE RS08155
gene id: 446465:BFAE_RS08155
uniprot id: C7MD18
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS02825
gene id: 446465:BFAE_RS02825
uniprot id: C7MI14
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS12910
gene id: 446465:BFAE_RS12910
uniprot id: C7MGE7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

446465:BFAE RS11785
gene id: 446465:BFAE_RS11785
uniprot id: C7MFF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

446465:BFAE RS06115
gene id: 446465:BFAE_RS06115
uniprot id: C7MBX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446465:BFAE RS10850
gene id: 446465:BFAE_RS10850
uniprot id: C7MEI3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

446465:BFAE RS03500
gene id: 446465:BFAE_RS03500
uniprot id: C7M9M7
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS07605
gene id: 446465:BFAE_RS07605
uniprot id: C7MCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS15245
gene id: 446465:BFAE_RS15245
uniprot id: C7MAU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

446465:BFAE RS01240
gene id: 446465:BFAE_RS01240
uniprot id: C7MG13
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

446465:BFAE RS14930
gene id: 446465:BFAE_RS14930
uniprot id: C7MAA1
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

446465:BFAE RS11550
gene id: 446465:BFAE_RS11550
uniprot id: C7MEX3
names: Similarity
messages: Belongs to the GARS family.

446465:BFAE RS14835
gene id: 446465:BFAE_RS14835
uniprot id: C7MA82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

446465:BFAE RS14390
gene id: 446465:BFAE_RS14390
uniprot id: C7MHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS10355
gene id: 446465:BFAE_RS10355
uniprot id: C7ME90
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

446465:BFAE RS01345
gene id: 446465:BFAE_RS01345
uniprot id: C7MG34
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

446465:BFAE RS08000
gene id: 446465:BFAE_RS08000
uniprot id: C7MCY8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

446465:BFAE RS08260
gene id: 446465:BFAE_RS08260
uniprot id: C7MD38
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

446465:BFAE RS11770
gene id: 446465:BFAE_RS11770
uniprot id: C7MFF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

446465:BFAE RS08395
gene id: 446465:BFAE_RS08395
uniprot id: C7MD62
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

446465:BFAE RS06195
gene id: 446465:BFAE_RS06195
uniprot id: C7MBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS01320
gene id: 446465:BFAE_RS01320
uniprot id: C7MG29
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

446465:BFAE RS09750
gene id: 446465:BFAE_RS09750
uniprot id: C7MDX3
names: Similarity
messages: Belongs to the GcvT family.

446465:BFAE RS01230
gene id: 446465:BFAE_RS01230
uniprot id: C7MG11
names: Similarity
messages: Belongs to the TPP enzyme family.

446465:BFAE RS01955
gene id: 446465:BFAE_RS01955
uniprot id: C7MGT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446465:BFAE RS12625
gene id: 446465:BFAE_RS12625
uniprot id: C7MG91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS14285
gene id: 446465:BFAE_RS14285
uniprot id: C7MHX6
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS04985
gene id: 446465:BFAE_RS04985
uniprot id: C7MB85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

446465:BFAE RS08980
gene id: 446465:BFAE_RS08980
uniprot id: C7MDH8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS08690
gene id: 446465:BFAE_RS08690
uniprot id: C7MDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

446465:BFAE RS09810
gene id: 446465:BFAE_RS09810
uniprot id: C7MDY5
names: Similarity
messages: Belongs to the CsoR family.

446465:BFAE RS05005
gene id: 446465:BFAE_RS05005
uniprot id: C7MB89
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS10535
gene id: 446465:BFAE_RS10535
uniprot id: C7MEC6
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS10880
gene id: 446465:BFAE_RS10880
uniprot id: C7MEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

446465:BFAE RS11170
gene id: 446465:BFAE_RS11170
uniprot id: C7MEQ2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446465:BFAE RS07520
gene id: 446465:BFAE_RS07520
uniprot id: C7MCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

446465:BFAE RS13295
gene id: 446465:BFAE_RS13295
uniprot id: C7MH04
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

446465:BFAE RS07310
gene id: 446465:BFAE_RS07310
uniprot id: C7MCK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

446465:BFAE RS09525
gene id: 446465:BFAE_RS09525
uniprot id: C7MDT3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

446465:BFAE RS10575
gene id: 446465:BFAE_RS10575
uniprot id: C7MED4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

446465:BFAE RS14080
gene id: 446465:BFAE_RS14080
uniprot id: C7MHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS11365
gene id: 446465:BFAE_RS11365
uniprot id: C7MET6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

446465:BFAE RS13220
gene id: 446465:BFAE_RS13220
uniprot id: C7MGY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

446465:BFAE RS12980
gene id: 446465:BFAE_RS12980
uniprot id: C7MGF9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

446465:BFAE RS09495
gene id: 446465:BFAE_RS09495
uniprot id: C7MDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

446465:BFAE RS00610
gene id: 446465:BFAE_RS00610
uniprot id: C7MFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS06735
gene id: 446465:BFAE_RS06735
uniprot id: C7MC95
names: Similarity
messages: Belongs to the TlyA family.

446465:BFAE RS00700
gene id: 446465:BFAE_RS00700
uniprot id: C7MFC3
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS12730
gene id: 446465:BFAE_RS12730
uniprot id: C7MGB2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446465:BFAE RS10330
gene id: 446465:BFAE_RS10330
uniprot id: C7ME85
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

446465:BFAE RS04935
gene id: 446465:BFAE_RS04935
uniprot id: C7MB75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

446465:BFAE RS09145
gene id: 446465:BFAE_RS09145
uniprot id: C7MDL0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

446465:BFAE RS13915
gene id: 446465:BFAE_RS13915
uniprot id: C7MHQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS14545
gene id: 446465:BFAE_RS14545
uniprot id: C7MA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS06450
gene id: 446465:BFAE_RS06450
uniprot id: C7MC43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

446465:BFAE RS10420
gene id: 446465:BFAE_RS10420
uniprot id: C7MEA3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

446465:BFAE RS00135
gene id: 446465:BFAE_RS00135
uniprot id: C7MF13
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS09940
gene id: 446465:BFAE_RS09940
uniprot id: C7ME08
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

446465:BFAE RS03620
gene id: 446465:BFAE_RS03620
uniprot id: C7M9Q1
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS08950
gene id: 446465:BFAE_RS08950
uniprot id: C7MDH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446465:BFAE RS01615
gene id: 446465:BFAE_RS01615
uniprot id: C7MGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

446465:BFAE RS05330
gene id: 446465:BFAE_RS05330
uniprot id: C7MBF5
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS10925
gene id: 446465:BFAE_RS10925
uniprot id: C7MEJ9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

446465:BFAE RS13105
gene id: 446465:BFAE_RS13105
uniprot id: C7MGW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446465:BFAE RS03800
gene id: 446465:BFAE_RS03800
uniprot id: C7M9T6
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS08620
gene id: 446465:BFAE_RS08620
uniprot id: C7MDA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

446465:BFAE RS08100
gene id: 446465:BFAE_RS08100
uniprot id: C7MD07
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

446465:BFAE RS03465
gene id: 446465:BFAE_RS03465
uniprot id: C7M9M0
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

446465:BFAE RS11575
gene id: 446465:BFAE_RS11575
uniprot id: C7MEX8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

446465:BFAE RS02560
gene id: 446465:BFAE_RS02560
uniprot id: C7MHH9
names: Similarity
messages: Belongs to the peptidase C69 family.

446465:BFAE RS11710
gene id: 446465:BFAE_RS11710
uniprot id: C7MFD8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

446465:BFAE RS13590
gene id: 446465:BFAE_RS13590
uniprot id: C7MH59
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446465:BFAE RS14045
gene id: 446465:BFAE_RS14045
uniprot id: C7MHS9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS12645
gene id: 446465:BFAE_RS12645
uniprot id: C7MG95
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS00795
gene id: 446465:BFAE_RS00795
uniprot id: C7MFS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446465:BFAE RS11445
gene id: 446465:BFAE_RS11445
uniprot id: C7MEV2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

446465:BFAE RS03550
gene id: 446465:BFAE_RS03550
uniprot id: C7M9N7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS05460
gene id: 446465:BFAE_RS05460
uniprot id: C7MBI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07180
gene id: 446465:BFAE_RS07180
uniprot id: C7MCH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

446465:BFAE RS07370
gene id: 446465:BFAE_RS07370
uniprot id: C7MCL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

446465:BFAE RS00350
gene id: 446465:BFAE_RS00350
uniprot id: C7MF56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS12540
gene id: 446465:BFAE_RS12540
uniprot id: C7MG74
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS10480
gene id: 446465:BFAE_RS10480
uniprot id: C7MEB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

446465:BFAE RS00165
gene id: 446465:BFAE_RS00165
uniprot id: C7MF19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

446465:BFAE RS01680
gene id: 446465:BFAE_RS01680
uniprot id: C7MGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS15535
gene id: 446465:BFAE_RS15535
uniprot id: C7MB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS15485
gene id: 446465:BFAE_RS15485
uniprot id: C7MAZ4
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS14820
gene id: 446465:BFAE_RS14820
uniprot id: C7MA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS13170
gene id: 446465:BFAE_RS13170
uniprot id: C7MGX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446465:BFAE RS04670
gene id: 446465:BFAE_RS04670
uniprot id: C7MAP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

446465:BFAE RS01745
gene id: 446465:BFAE_RS01745
uniprot id: C7MGP0
names: Similarity
messages: Belongs to the Dps family.

446465:BFAE RS13585
gene id: 446465:BFAE_RS13585
uniprot id: C7MH58
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS11980
gene id: 446465:BFAE_RS11980
uniprot id: C7MFJ1
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

446465:BFAE RS08295
gene id: 446465:BFAE_RS08295
uniprot id: C7MD44
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

446465:BFAE RS11480
gene id: 446465:BFAE_RS11480
uniprot id: C7MEV9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

446465:BFAE RS11300
gene id: 446465:BFAE_RS11300
uniprot id: C7MES6
names: Similarity
messages: Belongs to the YjdM family.

446465:BFAE RS12070
gene id: 446465:BFAE_RS12070
uniprot id: C7MFK8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS01685
gene id: 446465:BFAE_RS01685
uniprot id: C7MGM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

446465:BFAE RS13470
gene id: 446465:BFAE_RS13470
uniprot id: C7MH37
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: Belongs to the fatty acyl-CoA reductase family.

446465:BFAE RS09280
gene id: 446465:BFAE_RS09280
uniprot id: C7MDN4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

446465:BFAE RS02865
gene id: 446465:BFAE_RS02865
uniprot id: C7MI22
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS12490
gene id: 446465:BFAE_RS12490
uniprot id: C7MG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS08570
gene id: 446465:BFAE_RS08570
uniprot id: C7MD97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

446465:BFAE RS08240
gene id: 446465:BFAE_RS08240
uniprot id: C7MD34
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

446465:BFAE RS11385
gene id: 446465:BFAE_RS11385
uniprot id: C7MEU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

446465:BFAE RS02735
gene id: 446465:BFAE_RS02735
uniprot id: C7MHL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS06655
gene id: 446465:BFAE_RS06655
uniprot id: C7MC82
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

446465:BFAE RS13270
gene id: 446465:BFAE_RS13270
uniprot id: C7MGZ9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

446465:BFAE RS09000
gene id: 446465:BFAE_RS09000
uniprot id: C7MDI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

446465:BFAE RS02800
gene id: 446465:BFAE_RS02800
uniprot id: C7MI09
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

446465:BFAE RS01225
gene id: 446465:BFAE_RS01225
uniprot id: C7MG10
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS11995
gene id: 446465:BFAE_RS11995
uniprot id: C7MFJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446465:BFAE RS10760
gene id: 446465:BFAE_RS10760
uniprot id: C7MEG5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

446465:BFAE RS14740
gene id: 446465:BFAE_RS14740
uniprot id: C7MA63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS12310
gene id: 446465:BFAE_RS12310
uniprot id: C7MFP9
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

446465:BFAE RS05080
gene id: 446465:BFAE_RS05080
uniprot id: C7MBA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

446465:BFAE RS03510
gene id: 446465:BFAE_RS03510
uniprot id: C7M9M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

446465:BFAE RS14880
gene id: 446465:BFAE_RS14880
uniprot id: C7MA91
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446465:BFAE RS10055
gene id: 446465:BFAE_RS10055
uniprot id: C7ME30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

446465:BFAE RS02465
gene id: 446465:BFAE_RS02465
uniprot id: C7MHG1
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

446465:BFAE RS11495
gene id: 446465:BFAE_RS11495
uniprot id: C7MEW2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS13215
gene id: 446465:BFAE_RS13215
uniprot id: C7MGY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS11015
gene id: 446465:BFAE_RS11015
uniprot id: C7MEM3
names: Similarity
messages: Belongs to the acylphosphatase family.

446465:BFAE RS04525
gene id: 446465:BFAE_RS04525
uniprot id: C7MAL3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446465:BFAE RS14585
gene id: 446465:BFAE_RS14585
uniprot id: C7MA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS13210
gene id: 446465:BFAE_RS13210
uniprot id: C7MGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS04030
gene id: 446465:BFAE_RS04030
uniprot id: C7M9Y0
names: Similarity
messages: Belongs to the malate synthase family.

446465:BFAE RS14770
gene id: 446465:BFAE_RS14770
uniprot id: C7MA69
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446465:BFAE RS09185
gene id: 446465:BFAE_RS09185
uniprot id: C7MDL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

446465:BFAE RS04255
gene id: 446465:BFAE_RS04255
uniprot id: C7MAG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

446465:BFAE RS10315
gene id: 446465:BFAE_RS10315
uniprot id: C7ME82
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446465:BFAE RS11740
gene id: 446465:BFAE_RS11740
uniprot id: C7MFE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

446465:BFAE RS12305
gene id: 446465:BFAE_RS12305
uniprot id: C7MFP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS13605
gene id: 446465:BFAE_RS13605
uniprot id: C7MH62
names: Similarity
messages: Belongs to the AHA1 family.

446465:BFAE RS09520
gene id: 446465:BFAE_RS09520
uniprot id: C7MDT2
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

446465:BFAE RS05320
gene id: 446465:BFAE_RS05320
uniprot id: C7MBF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

446465:BFAE RS14005
gene id: 446465:BFAE_RS14005
uniprot id: C7MHS1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

446465:BFAE RS00205
gene id: 446465:BFAE_RS00205
uniprot id: C7MF27
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446465:BFAE RS15870
gene id: 446465:BFAE_RS15870
uniprot id: C7MBK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

446465:BFAE RS13810
gene id: 446465:BFAE_RS13810
uniprot id: C7MHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS08815
gene id: 446465:BFAE_RS08815
uniprot id: C7MDE5
names: Similarity
messages: Belongs to the UPF0371 family.

446465:BFAE RS04295
gene id: 446465:BFAE_RS04295
uniprot id: C7MAG8
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

446465:BFAE RS10125
gene id: 446465:BFAE_RS10125
uniprot id: C7ME44
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

446465:BFAE RS08470
gene id: 446465:BFAE_RS08470
uniprot id: C7MD77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

446465:BFAE RS11270
gene id: 446465:BFAE_RS11270
uniprot id: C7MES0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

446465:BFAE RS11105
gene id: 446465:BFAE_RS11105
uniprot id: C7MEP2
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

446465:BFAE RS12480
gene id: 446465:BFAE_RS12480
uniprot id: C7MG63
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

446465:BFAE RS09785
gene id: 446465:BFAE_RS09785
uniprot id: C7MDY0
names: Similarity
messages: Belongs to the cytochrome P450 family.

446465:BFAE RS02105
gene id: 446465:BFAE_RS02105
uniprot id: C7MH92
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446465:BFAE RS13580
gene id: 446465:BFAE_RS13580
uniprot id: C7MH57
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

446465:BFAE RS11005
gene id: 446465:BFAE_RS11005
uniprot id: C7MEM1
names: Similarity
messages: Belongs to the XFP family.

446465:BFAE RS09485
gene id: 446465:BFAE_RS09485
uniprot id: C7MDS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

446465:BFAE RS08125
gene id: 446465:BFAE_RS08125
uniprot id: C7MD12
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

446465:BFAE RS11940
gene id: 446465:BFAE_RS11940
uniprot id: C7MFI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

446465:BFAE RS06110
gene id: 446465:BFAE_RS06110
uniprot id: C7MBX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446465:BFAE RS02265
gene id: 446465:BFAE_RS02265
uniprot id: C7MHC2
names: Similarity
messages: Belongs to the DSD1 family.

446465:BFAE RS13995
gene id: 446465:BFAE_RS13995
uniprot id: C7MHR9
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS15325
gene id: 446465:BFAE_RS15325
uniprot id: C7MAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

446465:BFAE RS11355
gene id: 446465:BFAE_RS11355
uniprot id: C7MET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446465:BFAE RS09645
gene id: 446465:BFAE_RS09645
uniprot id: C7MDV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

446465:BFAE RS12015
gene id: 446465:BFAE_RS12015
uniprot id: C7MFJ8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS15660
gene id: 446465:BFAE_RS15660
uniprot id: C7MB29
names: Similarity
messages: Belongs to the peptidase C56 family.

446465:BFAE RS11725
gene id: 446465:BFAE_RS11725
uniprot id: C7MFE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

446465:BFAE RS08710
gene id: 446465:BFAE_RS08710
uniprot id: C7MDC5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446465:BFAE RS02055
gene id: 446465:BFAE_RS02055
uniprot id: C7MGV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS04455
gene id: 446465:BFAE_RS04455
uniprot id: C7MAK0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446465:BFAE RS02320
gene id: 446465:BFAE_RS02320
uniprot id: C7MHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

446465:BFAE RS04090
gene id: 446465:BFAE_RS04090
uniprot id: C7M9Z1
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

446465:BFAE RS06675
gene id: 446465:BFAE_RS06675
uniprot id: C7MC86
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

446465:BFAE RS01035
gene id: 446465:BFAE_RS01035
uniprot id: C7MFX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

446465:BFAE RS00640
gene id: 446465:BFAE_RS00640
uniprot id: C7MFB1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS13880
gene id: 446465:BFAE_RS13880
uniprot id: C7MHP5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

446465:BFAE RS03715
gene id: 446465:BFAE_RS03715
uniprot id: C7M9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

446465:BFAE RS14375
gene id: 446465:BFAE_RS14375
uniprot id: C7MHZ3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

446465:BFAE RS04535
gene id: 446465:BFAE_RS04535
uniprot id: C7MAL5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

446465:BFAE RS07375
gene id: 446465:BFAE_RS07375
uniprot id: C7MCL7
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

446465:BFAE RS14065
gene id: 446465:BFAE_RS14065
uniprot id: C7MHT3
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS02900
gene id: 446465:BFAE_RS02900
uniprot id: C7MI29
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

446465:BFAE RS04305
gene id: 446465:BFAE_RS04305
uniprot id: C7MAH0
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

446465:BFAE RS03735
gene id: 446465:BFAE_RS03735
uniprot id: C7M9S3
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS12505
gene id: 446465:BFAE_RS12505
uniprot id: C7MG68
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS04200
gene id: 446465:BFAE_RS04200
uniprot id: C7MAE9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

446465:BFAE RS02075
gene id: 446465:BFAE_RS02075
uniprot id: C7MGV4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

446465:BFAE RS03665
gene id: 446465:BFAE_RS03665
uniprot id: C7M9R0
names: Similarity
messages: Belongs to the glycosyl hydrolase.

446465:BFAE RS09350
gene id: 446465:BFAE_RS09350
uniprot id: C7MDP8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

446465:BFAE RS11585
gene id: 446465:BFAE_RS11585
uniprot id: C7MEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446465:BFAE RS07535
gene id: 446465:BFAE_RS07535
uniprot id: C7MCP7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS01315
gene id: 446465:BFAE_RS01315
uniprot id: C7MG28
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

446465:BFAE RS15215
gene id: 446465:BFAE_RS15215
uniprot id: C7MAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

446465:BFAE RS08490
gene id: 446465:BFAE_RS08490
uniprot id: C7MD81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

446465:BFAE RS02740
gene id: 446465:BFAE_RS02740
uniprot id: C7MHL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS10935
gene id: 446465:BFAE_RS10935
uniprot id: C7MEK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS13250
gene id: 446465:BFAE_RS13250
uniprot id: C7MGZ5
names: Similarity
messages: Belongs to the peptidase M18 family.

446465:BFAE RS02280
gene id: 446465:BFAE_RS02280
uniprot id: C7MHC5
names: Similarity
messages: Belongs to the proline racemase family.

446465:BFAE RS15220
gene id: 446465:BFAE_RS15220
uniprot id: C7MAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

446465:BFAE RS08550
gene id: 446465:BFAE_RS08550
uniprot id: C7MD93
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

446465:BFAE RS05265
gene id: 446465:BFAE_RS05265
uniprot id: C7MBE2
names: Subcellular Location Annotation
messages: Cytoplasm

446465:BFAE RS01755
gene id: 446465:BFAE_RS01755
uniprot id: C7MGP2
names: Similarity
messages: Belongs to the SufE family.

446465:BFAE RS09835
gene id: 446465:BFAE_RS09835
uniprot id: C7MDZ0
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS07030
gene id: 446465:BFAE_RS07030
uniprot id: C7MCE8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS01510
gene id: 446465:BFAE_RS01510
uniprot id: C7MGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446465:BFAE RS07320
gene id: 446465:BFAE_RS07320
uniprot id: C7MCK6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS15700
gene id: 446465:BFAE_RS15700
uniprot id: C7MB37
names: Similarity
messages: Belongs to the DapA family.

446465:BFAE RS05165
gene id: 446465:BFAE_RS05165
uniprot id: C7MBC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

446465:BFAE RS12495
gene id: 446465:BFAE_RS12495
uniprot id: C7MG66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS12820
gene id: 446465:BFAE_RS12820
uniprot id: C7MGD1
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS08080
gene id: 446465:BFAE_RS08080
uniprot id: C7MD03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

446465:BFAE RS09580
gene id: 446465:BFAE_RS09580
uniprot id: C7MDU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

446465:BFAE RS03970
gene id: 446465:BFAE_RS03970
uniprot id: C7M9W8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

446465:BFAE RS06360
gene id: 446465:BFAE_RS06360
uniprot id: C7MC25
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS09095
gene id: 446465:BFAE_RS09095
uniprot id: C7MDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

446465:BFAE RS15630
gene id: 446465:BFAE_RS15630
uniprot id: C7MB23
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS00140
gene id: 446465:BFAE_RS00140
uniprot id: C7MF14
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

446465:BFAE RS02150
gene id: 446465:BFAE_RS02150
uniprot id: C7MHA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446465:BFAE RS12630
gene id: 446465:BFAE_RS12630
uniprot id: C7MG92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS00045
gene id: 446465:BFAE_RS00045
uniprot id: C7MEZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

446465:BFAE RS09490
gene id: 446465:BFAE_RS09490
uniprot id: C7MDS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

446465:BFAE RS09830
gene id: 446465:BFAE_RS09830
uniprot id: C7MDY9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446465:BFAE RS05230
gene id: 446465:BFAE_RS05230
uniprot id: C7MBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

446465:BFAE RS05115
gene id: 446465:BFAE_RS05115
uniprot id: C7MBB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

446465:BFAE RS08275
gene id: 446465:BFAE_RS08275
uniprot id: C7MD40
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

446465:BFAE RS05000
gene id: 446465:BFAE_RS05000
uniprot id: C7MB88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

446465:BFAE RS11895
gene id: 446465:BFAE_RS11895
uniprot id: C7MFH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

446465:BFAE RS01855
gene id: 446465:BFAE_RS01855
uniprot id: C7MGR1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

446465:BFAE RS11775
gene id: 446465:BFAE_RS11775
uniprot id: C7MFF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

446465:BFAE RS12080
gene id: 446465:BFAE_RS12080
uniprot id: C7MFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

446465:BFAE RS13415
gene id: 446465:BFAE_RS13415
uniprot id: C7MH27
names: Similarity
messages: Belongs to the UPF0749 family.

446465:BFAE RS04950
gene id: 446465:BFAE_RS04950
uniprot id: C7MB78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

446465:BFAE RS08970
gene id: 446465:BFAE_RS08970
uniprot id: C7MDH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

446465:BFAE RS03860
gene id: 446465:BFAE_RS03860
uniprot id: C7M9U8
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

446465:BFAE RS14890
gene id: 446465:BFAE_RS14890
uniprot id: C7MA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS04175
gene id: 446465:BFAE_RS04175
uniprot id: C7MAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS11505
gene id: 446465:BFAE_RS11505
uniprot id: C7MEW4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

446465:BFAE RS11070
gene id: 446465:BFAE_RS11070
uniprot id: C7MEN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

446465:BFAE RS01250
gene id: 446465:BFAE_RS01250
uniprot id: C7MG15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446465:BFAE RS04220
gene id: 446465:BFAE_RS04220
uniprot id: C7MAF3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

446465:BFAE RS02835
gene id: 446465:BFAE_RS02835
uniprot id: C7MI16
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

446465:BFAE RS01965
gene id: 446465:BFAE_RS01965
uniprot id: C7MGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS01925
gene id: 446465:BFAE_RS01925
uniprot id: C7MGS5
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

446465:BFAE RS11685
gene id: 446465:BFAE_RS11685
uniprot id: C7MFD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446465:BFAE RS01070
gene id: 446465:BFAE_RS01070
uniprot id: C7MFY0
names: Similarity
messages: Belongs to the YciI family.

446465:BFAE RS10740
gene id: 446465:BFAE_RS10740
uniprot id: C7MEG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

446465:BFAE RS15640
gene id: 446465:BFAE_RS15640
uniprot id: C7MB25
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS13380
gene id: 446465:BFAE_RS13380
uniprot id: C7MH20
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS07880
gene id: 446465:BFAE_RS07880
uniprot id: C7MCW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS05705
gene id: 446465:BFAE_RS05705
uniprot id: C7MBP5
names: Similarity
messages: Belongs to the peptidase M1 family.

446465:BFAE RS10080
gene id: 446465:BFAE_RS10080
uniprot id: C7ME35
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

446465:BFAE RS06305
gene id: 446465:BFAE_RS06305
uniprot id: C7MC14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

446465:BFAE RS06230
gene id: 446465:BFAE_RS06230
uniprot id: C7MBZ9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS14780
gene id: 446465:BFAE_RS14780
uniprot id: C7MA71
names: Similarity
messages: Belongs to the LacAB/RpiB family.

446465:BFAE RS09335
gene id: 446465:BFAE_RS09335
uniprot id: C7MDP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS02165
gene id: 446465:BFAE_RS02165
uniprot id: C7MHA5
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS11265
gene id: 446465:BFAE_RS11265
uniprot id: C7MER9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS12800
gene id: 446465:BFAE_RS12800
uniprot id: C7MGC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446465:BFAE RS14250
gene id: 446465:BFAE_RS14250
uniprot id: C7MHW9
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS03765
gene id: 446465:BFAE_RS03765
uniprot id: C7M9S9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

446465:BFAE RS14970
gene id: 446465:BFAE_RS14970
uniprot id: C7MAA9
names: Similarity
messages: Belongs to the AHA1 family.

446465:BFAE RS03360
gene id: 446465:BFAE_RS03360
uniprot id: C7MIB9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

446465:BFAE RS14875
gene id: 446465:BFAE_RS14875
uniprot id: C7MA90
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446465:BFAE RS03070
gene id: 446465:BFAE_RS03070
uniprot id: C7MI63
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

446465:BFAE RS04050
gene id: 446465:BFAE_RS04050
uniprot id: C7M9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

446465:BFAE RS11840
gene id: 446465:BFAE_RS11840
uniprot id: C7MFG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

446465:BFAE RS11675
gene id: 446465:BFAE_RS11675
uniprot id: C7MFD1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

446465:BFAE RS07890
gene id: 446465:BFAE_RS07890
uniprot id: C7MCW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

446465:BFAE RS13495
gene id: 446465:BFAE_RS13495
uniprot id: C7MH42
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

446465:BFAE RS06710
gene id: 446465:BFAE_RS06710
uniprot id: C7MC90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07970
gene id: 446465:BFAE_RS07970
uniprot id: C7MCY2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

446465:BFAE RS09025
gene id: 446465:BFAE_RS09025
uniprot id: C7MDI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

446465:BFAE RS09420
gene id: 446465:BFAE_RS09420
uniprot id: C7MDR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446465:BFAE RS05040
gene id: 446465:BFAE_RS05040
uniprot id: C7MB97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

446465:BFAE RS03255
gene id: 446465:BFAE_RS03255
uniprot id: C7MIA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

446465:BFAE RS06395
gene id: 446465:BFAE_RS06395
uniprot id: C7MC32
names: Similarity
messages: Belongs to the MQO family.

446465:BFAE RS03470
gene id: 446465:BFAE_RS03470
uniprot id: C7M9M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS12715
gene id: 446465:BFAE_RS12715
uniprot id: C7MGA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

446465:BFAE RS08475
gene id: 446465:BFAE_RS08475
uniprot id: C7MD78
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

446465:BFAE RS11405
gene id: 446465:BFAE_RS11405
uniprot id: C7MEU4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

446465:BFAE RS05675
gene id: 446465:BFAE_RS05675
uniprot id: C7MBN9
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

446465:BFAE RS04395
gene id: 446465:BFAE_RS04395
uniprot id: C7MAI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

446465:BFAE RS15530
gene id: 446465:BFAE_RS15530
uniprot id: C7MB03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS02845
gene id: 446465:BFAE_RS02845
uniprot id: C7MI18
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

446465:BFAE RS07445
gene id: 446465:BFAE_RS07445
uniprot id: C7MCN0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

446465:BFAE RS04835
gene id: 446465:BFAE_RS04835
uniprot id: C7MB56
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS14565
gene id: 446465:BFAE_RS14565
uniprot id: C7MA28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS10270
gene id: 446465:BFAE_RS10270
uniprot id: C7ME73
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS08390
gene id: 446465:BFAE_RS08390
uniprot id: C7MD61
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

446465:BFAE RS07620
gene id: 446465:BFAE_RS07620
uniprot id: C7MCR4
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

446465:BFAE RS14550
gene id: 446465:BFAE_RS14550
uniprot id: C7MA25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS09570
gene id: 446465:BFAE_RS09570
uniprot id: C7MDU2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

446465:BFAE RS06740
gene id: 446465:BFAE_RS06740
uniprot id: C7MC96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS03740
gene id: 446465:BFAE_RS03740
uniprot id: C7M9S4
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

446465:BFAE RS05920
gene id: 446465:BFAE_RS05920
uniprot id: C7MBT7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

446465:BFAE RS15670
gene id: 446465:BFAE_RS15670
uniprot id: C7MB31
names: Similarity
messages: Belongs to the proline racemase family.

446465:BFAE RS02025
gene id: 446465:BFAE_RS02025
uniprot id: C7MGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS13860
gene id: 446465:BFAE_RS13860
uniprot id: C7MHP1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

446465:BFAE RS15320
gene id: 446465:BFAE_RS15320
uniprot id: C7MAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

446465:BFAE RS06075
gene id: 446465:BFAE_RS06075
uniprot id: C7MBW8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

446465:BFAE RS08780
gene id: 446465:BFAE_RS08780
uniprot id: C7MDD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07850
gene id: 446465:BFAE_RS07850
uniprot id: C7MCV8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS03955
gene id: 446465:BFAE_RS03955
uniprot id: C7M9W5
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS09380
gene id: 446465:BFAE_RS09380
uniprot id: C7MDQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS05915
gene id: 446465:BFAE_RS05915
uniprot id: C7MBT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS01775
gene id: 446465:BFAE_RS01775
uniprot id: C7MGP6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

446465:BFAE RS01300
gene id: 446465:BFAE_RS01300
uniprot id: C7MG25
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS00870
gene id: 446465:BFAE_RS00870
uniprot id: C7MFT9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446465:BFAE RS11845
gene id: 446465:BFAE_RS11845
uniprot id: C7MFG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

446465:BFAE RS15665
gene id: 446465:BFAE_RS15665
uniprot id: C7MB30
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

446465:BFAE RS04420
gene id: 446465:BFAE_RS04420
uniprot id: C7MAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

446465:BFAE RS11205
gene id: 446465:BFAE_RS11205
uniprot id: C7MEQ7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

446465:BFAE RS01765
gene id: 446465:BFAE_RS01765
uniprot id: C7MGP4
names: Similarity
messages: Belongs to the asparaginase 1 family.

446465:BFAE RS05465
gene id: 446465:BFAE_RS05465
uniprot id: C7MBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS05440
gene id: 446465:BFAE_RS05440
uniprot id: C7MBH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS07010
gene id: 446465:BFAE_RS07010
uniprot id: C7MCE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS02705
gene id: 446465:BFAE_RS02705
uniprot id: C7MHK7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446465:BFAE RS01335
gene id: 446465:BFAE_RS01335
uniprot id: C7MG32
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

446465:BFAE RS05065
gene id: 446465:BFAE_RS05065
uniprot id: C7MBA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS05370
gene id: 446465:BFAE_RS05370
uniprot id: C7MBG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

446465:BFAE RS06310
gene id: 446465:BFAE_RS06310
uniprot id: C7MC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

446465:BFAE RS09330
gene id: 446465:BFAE_RS09330
uniprot id: C7MDP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS09595
gene id: 446465:BFAE_RS09595
uniprot id: C7MDU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

446465:BFAE RS06325
gene id: 446465:BFAE_RS06325
uniprot id: C7MC18
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

446465:BFAE RS03625
gene id: 446465:BFAE_RS03625
uniprot id: C7M9Q2
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

446465:BFAE RS08430
gene id: 446465:BFAE_RS08430
uniprot id: C7MD69
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446465:BFAE RS15865
gene id: 446465:BFAE_RS15865
uniprot id: C7MBK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

446465:BFAE RS01990
gene id: 446465:BFAE_RS01990
uniprot id: C7MGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446465:BFAE RS03645
gene id: 446465:BFAE_RS03645
uniprot id: C7M9Q6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS03090
gene id: 446465:BFAE_RS03090
uniprot id: C7MI67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS06505
gene id: 446465:BFAE_RS06505
uniprot id: C7MC53
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

446465:BFAE RS12970
gene id: 446465:BFAE_RS12970
uniprot id: C7MGF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS02795
gene id: 446465:BFAE_RS02795
uniprot id: C7MI08
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS02010
gene id: 446465:BFAE_RS02010
uniprot id: C7MGU2
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

446465:BFAE RS03655
gene id: 446465:BFAE_RS03655
uniprot id: C7M9Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS06910
gene id: 446465:BFAE_RS06910
uniprot id: C7MCC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS00395
gene id: 446465:BFAE_RS00395
uniprot id: C7MF63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS05175
gene id: 446465:BFAE_RS05175
uniprot id: C7MBC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

446465:BFAE RS03480
gene id: 446465:BFAE_RS03480
uniprot id: C7M9M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

446465:BFAE RS05315
gene id: 446465:BFAE_RS05315
uniprot id: C7MBF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS08500
gene id: 446465:BFAE_RS08500
uniprot id: C7MD83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446465:BFAE RS10770
gene id: 446465:BFAE_RS10770
uniprot id: C7MEG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

446465:BFAE RS08305
gene id: 446465:BFAE_RS08305
uniprot id: C7MD46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

446465:BFAE RS05995
gene id: 446465:BFAE_RS05995
uniprot id: C7MBV2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

446465:BFAE RS00815
gene id: 446465:BFAE_RS00815
uniprot id: C7MFS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS06615
gene id: 446465:BFAE_RS06615
uniprot id: C7MC74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

446465:BFAE RS06945
gene id: 446465:BFAE_RS06945
uniprot id: C7MCD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS07855
gene id: 446465:BFAE_RS07855
uniprot id: C7MCV9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

446465:BFAE RS02985
gene id: 446465:BFAE_RS02985
uniprot id: C7MI46
names: Similarity
messages: Belongs to the glutathione peroxidase family.

446465:BFAE RS10830
gene id: 446465:BFAE_RS10830
uniprot id: C7MEH9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

446465:BFAE RS04720
gene id: 446465:BFAE_RS04720
uniprot id: C7MAQ0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

446465:BFAE RS11560
gene id: 446465:BFAE_RS11560
uniprot id: C7MEX5
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS14225
gene id: 446465:BFAE_RS14225
uniprot id: C7MHW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446465:BFAE RS01770
gene id: 446465:BFAE_RS01770
uniprot id: C7MGP5
names: Similarity
messages: Belongs to the AHA1 family.

446465:BFAE RS10505
gene id: 446465:BFAE_RS10505
uniprot id: C7MEC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

446465:BFAE RS11830
gene id: 446465:BFAE_RS11830
uniprot id: C7MFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

446465:BFAE RS05160
gene id: 446465:BFAE_RS05160
uniprot id: C7MBC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

446465:BFAE RS13160
gene id: 446465:BFAE_RS13160
uniprot id: C7MGX7
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Siderophore-Fe(3+) uptake transporter (SIUT) (TC 3.A.1.21) family.
messages: Forms a heterodimer with IrtB.

446465:BFAE RS06405
gene id: 446465:BFAE_RS06405
uniprot id: C7MC34
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

446465:BFAE RS11280
gene id: 446465:BFAE_RS11280
uniprot id: C7MES2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

446465:BFAE RS06860
gene id: 446465:BFAE_RS06860
uniprot id: C7MCB4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS00005
gene id: 446465:BFAE_RS00005
uniprot id: C7MEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

446465:BFAE RS07565
gene id: 446465:BFAE_RS07565
uniprot id: C7MCQ3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

446465:BFAE RS14840
gene id: 446465:BFAE_RS14840
uniprot id: C7MA83
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS05485
gene id: 446465:BFAE_RS05485
uniprot id: C7MBI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

446465:BFAE RS08485
gene id: 446465:BFAE_RS08485
uniprot id: C7MD80
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

446465:BFAE RS08460
gene id: 446465:BFAE_RS08460
uniprot id: C7MD75
names: Similarity
messages: Belongs to the Fur family.

446465:BFAE RS00740
gene id: 446465:BFAE_RS00740
uniprot id: C7MFR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS02815
gene id: 446465:BFAE_RS02815
uniprot id: C7MI12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS08455
gene id: 446465:BFAE_RS08455
uniprot id: C7MD74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS09465
gene id: 446465:BFAE_RS09465
uniprot id: C7MDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane

446465:BFAE RS09300
gene id: 446465:BFAE_RS09300
uniprot id: C7MDN8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS15695
gene id: 446465:BFAE_RS15695
uniprot id: C7MB36
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446465:BFAE RS05610
gene id: 446465:BFAE_RS05610
uniprot id: C7MBM5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446465:BFAE RS02820
gene id: 446465:BFAE_RS02820
uniprot id: C7MI13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS14195
gene id: 446465:BFAE_RS14195
uniprot id: C7MHV9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

446465:BFAE RS09195
gene id: 446465:BFAE_RS09195
uniprot id: C7MDM0
names: Similarity
messages: Belongs to the universal stress protein A family.

446465:BFAE RS10745
gene id: 446465:BFAE_RS10745
uniprot id: C7MEG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS15845
gene id: 446465:BFAE_RS15845
uniprot id: C7MBJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

446465:BFAE RS07930
gene id: 446465:BFAE_RS07930
uniprot id: C7MCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

446465:BFAE RS06555
gene id: 446465:BFAE_RS06555
uniprot id: C7MC63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

446465:BFAE RS14580
gene id: 446465:BFAE_RS14580
uniprot id: C7MA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS12340
gene id: 446465:BFAE_RS12340
uniprot id: C7MFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

446465:BFAE RS09180
gene id: 446465:BFAE_RS09180
uniprot id: C7MDL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

446465:BFAE RS00745
gene id: 446465:BFAE_RS00745
uniprot id: C7MFR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

446465:BFAE RS09430
gene id: 446465:BFAE_RS09430
uniprot id: C7MDR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

446465:BFAE RS06070
gene id: 446465:BFAE_RS06070
uniprot id: C7MBW7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

446465:BFAE RS10765
gene id: 446465:BFAE_RS10765
uniprot id: C7MEG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

446465:BFAE RS01840
gene id: 446465:BFAE_RS01840
uniprot id: C7MGQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

446465:BFAE RS06355
gene id: 446465:BFAE_RS06355
uniprot id: C7MC24
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

446465:BFAE RS01105
gene id: 446465:BFAE_RS01105
uniprot id: C7MFY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07905
gene id: 446465:BFAE_RS07905
uniprot id: C7MCW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

446465:BFAE RS09690
gene id: 446465:BFAE_RS09690
uniprot id: C7MDW4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

446465:BFAE RS06635
gene id: 446465:BFAE_RS06635
uniprot id: C7MC78
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

446465:BFAE RS04995
gene id: 446465:BFAE_RS04995
uniprot id: C7MB87
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

446465:BFAE RS04480
gene id: 446465:BFAE_RS04480
uniprot id: C7MAK5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

446465:BFAE RS01610
gene id: 446465:BFAE_RS01610
uniprot id: C7MGL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

446465:BFAE RS09500
gene id: 446465:BFAE_RS09500
uniprot id: C7MDS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

446465:BFAE RS11525
gene id: 446465:BFAE_RS11525
uniprot id: C7MEW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

446465:BFAE RS08440
gene id: 446465:BFAE_RS08440
uniprot id: C7MD71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS14020
gene id: 446465:BFAE_RS14020
uniprot id: C7MHS4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446465:BFAE RS09160
gene id: 446465:BFAE_RS09160
uniprot id: C7MDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

446465:BFAE RS08650
gene id: 446465:BFAE_RS08650
uniprot id: C7MDB3
names: Similarity
messages: Belongs to the thymidine kinase family.

446465:BFAE RS11925
gene id: 446465:BFAE_RS11925
uniprot id: C7MFI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

446465:BFAE RS11875
gene id: 446465:BFAE_RS11875
uniprot id: C7MFH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

446465:BFAE RS03660
gene id: 446465:BFAE_RS03660
uniprot id: C7M9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS14955
gene id: 446465:BFAE_RS14955
uniprot id: C7MAA6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

446465:BFAE RS12570
gene id: 446465:BFAE_RS12570
uniprot id: C7MG80
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

446465:BFAE RS05800
gene id: 446465:BFAE_RS05800
uniprot id: C7MBR4
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS05130
gene id: 446465:BFAE_RS05130
uniprot id: C7MBB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

446465:BFAE RS07355
gene id: 446465:BFAE_RS07355
uniprot id: C7MCL3
names: Similarity
messages: Belongs to the TrpC family.

446465:BFAE RS00935
gene id: 446465:BFAE_RS00935
uniprot id: C7MFV3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS08600
gene id: 446465:BFAE_RS08600
uniprot id: C7MDA3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

446465:BFAE RS04705
gene id: 446465:BFAE_RS04705
uniprot id: C7MAP7
names: Similarity
messages: Belongs to the peptidase C40 family.

446465:BFAE RS07410
gene id: 446465:BFAE_RS07410
uniprot id: C7MCM3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

446465:BFAE RS07785
gene id: 446465:BFAE_RS07785
uniprot id: C7MCU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

446465:BFAE RS02550
gene id: 446465:BFAE_RS02550
uniprot id: C7MHH7
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

446465:BFAE RS10585
gene id: 446465:BFAE_RS10585
uniprot id: C7MED6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

446465:BFAE RS10205
gene id: 446465:BFAE_RS10205
uniprot id: C7ME60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

446465:BFAE RS00255
gene id: 446465:BFAE_RS00255
uniprot id: C7MF37
names: Similarity
messages: Belongs to the LacAB/RpiB family.

446465:BFAE RS14220
gene id: 446465:BFAE_RS14220
uniprot id: C7MHW4
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS04745
gene id: 446465:BFAE_RS04745
uniprot id: C7MAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

446465:BFAE RS03350
gene id: 446465:BFAE_RS03350
uniprot id: C7MIB7
names: Similarity
messages: Belongs to the universal stress protein A family.

446465:BFAE RS13125
gene id: 446465:BFAE_RS13125
uniprot id: C7MGX0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446465:BFAE RS06930
gene id: 446465:BFAE_RS06930
uniprot id: C7MCC8
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

446465:BFAE RS12600
gene id: 446465:BFAE_RS12600
uniprot id: C7MG86
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446465:BFAE RS08845
gene id: 446465:BFAE_RS08845
uniprot id: C7MDF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS02420
gene id: 446465:BFAE_RS02420
uniprot id: C7MHF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07270
gene id: 446465:BFAE_RS07270
uniprot id: C7MCJ6
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

446465:BFAE RS09030
gene id: 446465:BFAE_RS09030
uniprot id: C7MDI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

446465:BFAE RS11860
gene id: 446465:BFAE_RS11860
uniprot id: C7MFG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446465:BFAE RS01060
gene id: 446465:BFAE_RS01060
uniprot id: C7MFX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446465:BFAE RS13420
gene id: 446465:BFAE_RS13420
uniprot id: C7MH28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

446465:BFAE RS12720
gene id: 446465:BFAE_RS12720
uniprot id: C7MGB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

446465:BFAE RS06875
gene id: 446465:BFAE_RS06875
uniprot id: C7MCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

446465:BFAE RS10895
gene id: 446465:BFAE_RS10895
uniprot id: C7MEJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

446465:BFAE RS08545
gene id: 446465:BFAE_RS08545
uniprot id: C7MD92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

446465:BFAE RS05280
gene id: 446465:BFAE_RS05280
uniprot id: C7MBE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

446465:BFAE RS05635
gene id: 446465:BFAE_RS05635
uniprot id: C7MBN0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446465:BFAE RS13055
gene id: 446465:BFAE_RS13055
uniprot id: C7MGV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

446465:BFAE RS15280
gene id: 446465:BFAE_RS15280
uniprot id: C7MAV3
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS12370
gene id: 446465:BFAE_RS12370
uniprot id: C7MG45
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

446465:BFAE RS01520
gene id: 446465:BFAE_RS01520
uniprot id: C7MGJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS10120
gene id: 446465:BFAE_RS10120
uniprot id: C7ME43
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS14150
gene id: 446465:BFAE_RS14150
uniprot id: C7MHV0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

446465:BFAE RS00050
gene id: 446465:BFAE_RS00050
uniprot id: C7MEZ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

446465:BFAE RS04920
gene id: 446465:BFAE_RS04920
uniprot id: C7MB72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

446465:BFAE RS04005
gene id: 446465:BFAE_RS04005
uniprot id: C7M9X5
names: Similarity
messages: Belongs to the TPP enzyme family.

446465:BFAE RS09950
gene id: 446465:BFAE_RS09950
uniprot id: C7ME10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

446465:BFAE RS03900
gene id: 446465:BFAE_RS03900
uniprot id: C7M9V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

446465:BFAE RS05700
gene id: 446465:BFAE_RS05700
uniprot id: C7MBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

446465:BFAE RS09655
gene id: 446465:BFAE_RS09655
uniprot id: C7MDV8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

446465:BFAE RS11795
gene id: 446465:BFAE_RS11795
uniprot id: C7MFF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

446465:BFAE RS07760
gene id: 446465:BFAE_RS07760
uniprot id: C7MCU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

446465:BFAE RS04975
gene id: 446465:BFAE_RS04975
uniprot id: C7MB83
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

446465:BFAE RS06030
gene id: 446465:BFAE_RS06030
uniprot id: C7MBV9
names: Similarity
messages: Belongs to the UPF0098 family.

446465:BFAE RS06445
gene id: 446465:BFAE_RS06445
uniprot id: C7MC42
names: Similarity
messages: Belongs to the Nth/MutY family.

446465:BFAE RS10750
gene id: 446465:BFAE_RS10750
uniprot id: C7MEG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

446465:BFAE RS11790
gene id: 446465:BFAE_RS11790
uniprot id: C7MFF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

446465:BFAE RS00230
gene id: 446465:BFAE_RS00230
uniprot id: C7MF32
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446465:BFAE RS03730
gene id: 446465:BFAE_RS03730
uniprot id: C7M9S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

446465:BFAE RS09125
gene id: 446465:BFAE_RS09125
uniprot id: C7MDK6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

446465:BFAE RS05240
gene id: 446465:BFAE_RS05240
uniprot id: C7MBD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

446465:BFAE RS11765
gene id: 446465:BFAE_RS11765
uniprot id: C7MFE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

446465:BFAE RS10985
gene id: 446465:BFAE_RS10985
uniprot id: C7MEL7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

446465:BFAE RS02200
gene id: 446465:BFAE_RS02200
uniprot id: C7MHB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

446465:BFAE RS08210
gene id: 446465:BFAE_RS08210
uniprot id: C7MD29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

446465:BFAE RS00025
gene id: 446465:BFAE_RS00025
uniprot id: C7MEL1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

446465:BFAE RS09510
gene id: 446465:BFAE_RS09510
uniprot id: C7MDT0
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS05100
gene id: 446465:BFAE_RS05100
uniprot id: C7MBA9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

446465:BFAE RS11780
gene id: 446465:BFAE_RS11780
uniprot id: C7MFF2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

446465:BFAE RS09805
gene id: 446465:BFAE_RS09805
uniprot id: C7MDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446465:BFAE RS04370
gene id: 446465:BFAE_RS04370
uniprot id: C7MAI3
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

446465:BFAE RS07495
gene id: 446465:BFAE_RS07495
uniprot id: C7MCN9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

446465:BFAE RS05505
gene id: 446465:BFAE_RS05505
uniprot id: C7MBK5
names: Similarity
messages: Belongs to the citrate synthase family.

446465:BFAE RS01650
gene id: 446465:BFAE_RS01650
uniprot id: C7MGM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07160
gene id: 446465:BFAE_RS07160
uniprot id: C7MCH4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

446465:BFAE RS15765
gene id: 446465:BFAE_RS15765
uniprot id: C7MB48
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS08525
gene id: 446465:BFAE_RS08525
uniprot id: C7MD88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

446465:BFAE RS09250
gene id: 446465:BFAE_RS09250
uniprot id: C7MDM8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS09085
gene id: 446465:BFAE_RS09085
uniprot id: C7MDJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

446465:BFAE RS11635
gene id: 446465:BFAE_RS11635
uniprot id: C7MEZ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446465:BFAE RS06625
gene id: 446465:BFAE_RS06625
uniprot id: C7MC76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

446465:BFAE RS10345
gene id: 446465:BFAE_RS10345
uniprot id: C7ME88
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446465:BFAE RS05090
gene id: 446465:BFAE_RS05090
uniprot id: C7MBA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

446465:BFAE RS07765
gene id: 446465:BFAE_RS07765
uniprot id: C7MCU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

446465:BFAE RS02100
gene id: 446465:BFAE_RS02100
uniprot id: C7MH91
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS11885
gene id: 446465:BFAE_RS11885
uniprot id: C7MFH3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

446465:BFAE RS11760
gene id: 446465:BFAE_RS11760
uniprot id: C7MFE8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

446465:BFAE RS11175
gene id: 446465:BFAE_RS11175
uniprot id: C7MEQ3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

446465:BFAE RS12695
gene id: 446465:BFAE_RS12695
uniprot id: C7MGA5
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS11490
gene id: 446465:BFAE_RS11490
uniprot id: C7MEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

446465:BFAE RS12815
gene id: 446465:BFAE_RS12815
uniprot id: C7MGD0
names: Similarity
messages: Belongs to the GSP E family.

446465:BFAE RS10690
gene id: 446465:BFAE_RS10690
uniprot id: C7MEF4
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS13950
gene id: 446465:BFAE_RS13950
uniprot id: C7MHQ9
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Tetramer of two alpha and two beta subunits.

446465:BFAE RS14665
gene id: 446465:BFAE_RS14665
uniprot id: C7MA48
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

446465:BFAE RS05780
gene id: 446465:BFAE_RS05780
uniprot id: C7MBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

446465:BFAE RS10570
gene id: 446465:BFAE_RS10570
uniprot id: C7MED3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

446465:BFAE RS07365
gene id: 446465:BFAE_RS07365
uniprot id: C7MCL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

446465:BFAE RS14600
gene id: 446465:BFAE_RS14600
uniprot id: C7MA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07440
gene id: 446465:BFAE_RS07440
uniprot id: C7MCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

446465:BFAE RS00630
gene id: 446465:BFAE_RS00630
uniprot id: C7MFA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS15385
gene id: 446465:BFAE_RS15385
uniprot id: C7MAX4
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

446465:BFAE RS12710
gene id: 446465:BFAE_RS12710
uniprot id: C7MGA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

446465:BFAE RS04625
gene id: 446465:BFAE_RS04625
uniprot id: C7MAN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

446465:BFAE RS02345
gene id: 446465:BFAE_RS02345
uniprot id: C7MHD7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

446465:BFAE RS05340
gene id: 446465:BFAE_RS05340
uniprot id: C7MBF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

446465:BFAE RS11715
gene id: 446465:BFAE_RS11715
uniprot id: C7MFD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

446465:BFAE RS10115
gene id: 446465:BFAE_RS10115
uniprot id: C7ME42
names: Similarity
messages: Belongs to the GSP E family.

446465:BFAE RS10530
gene id: 446465:BFAE_RS10530
uniprot id: C7MEC5
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS03125
gene id: 446465:BFAE_RS03125
uniprot id: C7MI74
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS01545
gene id: 446465:BFAE_RS01545
uniprot id: C7MGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

446465:BFAE RS13165
gene id: 446465:BFAE_RS13165
uniprot id: C7MGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446465:BFAE RS09340
gene id: 446465:BFAE_RS09340
uniprot id: C7MDP6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

446465:BFAE RS12515
gene id: 446465:BFAE_RS12515
uniprot id: C7MG70
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS13290
gene id: 446465:BFAE_RS13290
uniprot id: C7MH03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS14915
gene id: 446465:BFAE_RS14915
uniprot id: C7MA98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS04490
gene id: 446465:BFAE_RS04490
uniprot id: C7MAK7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS12180
gene id: 446465:BFAE_RS12180
uniprot id: C7MFM6
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS08145
gene id: 446465:BFAE_RS08145
uniprot id: C7MD16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

446465:BFAE RS01700
gene id: 446465:BFAE_RS01700
uniprot id: C7MGN1
names: Similarity
messages: Belongs to the peptidase S9A family.

446465:BFAE RS03775
gene id: 446465:BFAE_RS03775
uniprot id: C7M9T1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

446465:BFAE RS09735
gene id: 446465:BFAE_RS09735
uniprot id: C7MDX1
names: Similarity
messages: Belongs to the UPF0045 family.

446465:BFAE RS13980
gene id: 446465:BFAE_RS13980
uniprot id: C7MHR6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

446465:BFAE RS05250
gene id: 446465:BFAE_RS05250
uniprot id: C7MBD9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

446465:BFAE RS13755
gene id: 446465:BFAE_RS13755
uniprot id: C7MHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS09575
gene id: 446465:BFAE_RS09575
uniprot id: C7MDU3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

446465:BFAE RS11680
gene id: 446465:BFAE_RS11680
uniprot id: C7MFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

446465:BFAE RS15180
gene id: 446465:BFAE_RS15180
uniprot id: C7MAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

446465:BFAE RS03820
gene id: 446465:BFAE_RS03820
uniprot id: C7M9U0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

446465:BFAE RS12805
gene id: 446465:BFAE_RS12805
uniprot id: C7MGC8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

446465:BFAE RS07175
gene id: 446465:BFAE_RS07175
uniprot id: C7MCH7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

446465:BFAE RS15145
gene id: 446465:BFAE_RS15145
uniprot id: C7MAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446465:BFAE RS07275
gene id: 446465:BFAE_RS07275
uniprot id: C7MCJ7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

446465:BFAE RS11910
gene id: 446465:BFAE_RS11910
uniprot id: C7MFH7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

446465:BFAE RS09120
gene id: 446465:BFAE_RS09120
uniprot id: C7MDK5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

446465:BFAE RS12295
gene id: 446465:BFAE_RS12295
uniprot id: C7MFP7
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS01695
gene id: 446465:BFAE_RS01695
uniprot id: C7MGN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446465:BFAE RS13310
gene id: 446465:BFAE_RS13310
uniprot id: C7MH07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS01970
gene id: 446465:BFAE_RS01970
uniprot id: C7MGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS01850
gene id: 446465:BFAE_RS01850
uniprot id: C7MGR0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

446465:BFAE RS04520
gene id: 446465:BFAE_RS04520
uniprot id: C7MAL2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

446465:BFAE RS15420
gene id: 446465:BFAE_RS15420
uniprot id: C7MAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS05095
gene id: 446465:BFAE_RS05095
uniprot id: C7MBA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

446465:BFAE RS10630
gene id: 446465:BFAE_RS10630
uniprot id: C7MEE2
names: Similarity
messages: Belongs to the UPF0234 family.

446465:BFAE RS15635
gene id: 446465:BFAE_RS15635
uniprot id: C7MB24
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS03910
gene id: 446465:BFAE_RS03910
uniprot id: C7M9V7
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS03995
gene id: 446465:BFAE_RS03995
uniprot id: C7M9X3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

446465:BFAE RS02415
gene id: 446465:BFAE_RS02415
uniprot id: C7MHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS08220
gene id: 446465:BFAE_RS08220
uniprot id: C7MD31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446465:BFAE RS00420
gene id: 446465:BFAE_RS00420
uniprot id: C7MF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS05545
gene id: 446465:BFAE_RS05545
uniprot id: C7MBL1
names: Similarity
messages: Belongs to the LOG family.

446465:BFAE RS14095
gene id: 446465:BFAE_RS14095
uniprot id: C7MHT9
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS03930
gene id: 446465:BFAE_RS03930
uniprot id: C7M9W0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

446465:BFAE RS08420
gene id: 446465:BFAE_RS08420
uniprot id: C7MD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS10500
gene id: 446465:BFAE_RS10500
uniprot id: C7MEB9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446465:BFAE RS07580
gene id: 446465:BFAE_RS07580
uniprot id: C7MCQ6
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS02670
gene id: 446465:BFAE_RS02670
uniprot id: C7MHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

446465:BFAE RS04970
gene id: 446465:BFAE_RS04970
uniprot id: C7MB82
names: Similarity
messages: Belongs to the UPF0102 family.

446465:BFAE RS12005
gene id: 446465:BFAE_RS12005
uniprot id: C7MFJ6
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS06095
gene id: 446465:BFAE_RS06095
uniprot id: C7MBX2
names: Similarity
messages: Belongs to the arginine deiminase family.

446465:BFAE RS02015
gene id: 446465:BFAE_RS02015
uniprot id: C7MGU3
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

446465:BFAE RS05335
gene id: 446465:BFAE_RS05335
uniprot id: C7MBF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS07315
gene id: 446465:BFAE_RS07315
uniprot id: C7MCK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446465:BFAE RS09315
gene id: 446465:BFAE_RS09315
uniprot id: C7MDP1
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

446465:BFAE RS11890
gene id: 446465:BFAE_RS11890
uniprot id: C7MFH4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

446465:BFAE RS04485
gene id: 446465:BFAE_RS04485
uniprot id: C7MAK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

446465:BFAE RS06995
gene id: 446465:BFAE_RS06995
uniprot id: C7MCE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

446465:BFAE RS13890
gene id: 446465:BFAE_RS13890
uniprot id: C7MHP7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446465:BFAE RS11735
gene id: 446465:BFAE_RS11735
uniprot id: C7MFE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

446465:BFAE RS00290
gene id: 446465:BFAE_RS00290
uniprot id: C7MF44
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

446465:BFAE RS09740
gene id: 446465:BFAE_RS09740
uniprot id: C7MDX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

446465:BFAE RS15555
gene id: 446465:BFAE_RS15555
uniprot id: C7MB08
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS11380
gene id: 446465:BFAE_RS11380
uniprot id: C7MET9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

446465:BFAE RS05010
gene id: 446465:BFAE_RS05010
uniprot id: C7MB90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

446465:BFAE RS12195
gene id: 446465:BFAE_RS12195
uniprot id: C7MFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS10320
gene id: 446465:BFAE_RS10320
uniprot id: C7ME83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS08250
gene id: 446465:BFAE_RS08250
uniprot id: C7MD36
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

446465:BFAE RS11695
gene id: 446465:BFAE_RS11695
uniprot id: C7MFD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

446465:BFAE RS10715
gene id: 446465:BFAE_RS10715
uniprot id: C7MEF9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

446465:BFAE RS09630
gene id: 446465:BFAE_RS09630
uniprot id: C7MDV3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446465:BFAE RS14795
gene id: 446465:BFAE_RS14795
uniprot id: C7MA74
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS02295
gene id: 446465:BFAE_RS02295
uniprot id: C7MHC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446465:BFAE RS00755
gene id: 446465:BFAE_RS00755
uniprot id: C7MFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS09555
gene id: 446465:BFAE_RS09555
uniprot id: C7MDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS14200
gene id: 446465:BFAE_RS14200
uniprot id: C7MHW0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446465:BFAE RS01270
gene id: 446465:BFAE_RS01270
uniprot id: C7MG19
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS00040
gene id: 446465:BFAE_RS00040
uniprot id: C7MEZ6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

446465:BFAE RS15580
gene id: 446465:BFAE_RS15580
uniprot id: C7MB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446465:BFAE RS13300
gene id: 446465:BFAE_RS13300
uniprot id: C7MH05
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

446465:BFAE RS06160
gene id: 446465:BFAE_RS06160
uniprot id: C7MBY5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

446465:BFAE RS09530
gene id: 446465:BFAE_RS09530
uniprot id: C7MDT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

446465:BFAE RS12160
gene id: 446465:BFAE_RS12160
uniprot id: C7MFM2
names: Similarity
messages: Belongs to the peptidase S9C family.

446465:BFAE RS06890
gene id: 446465:BFAE_RS06890
uniprot id: C7MCC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

446465:BFAE RS14365
gene id: 446465:BFAE_RS14365
uniprot id: C7MHZ1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

446465:BFAE RS01185
gene id: 446465:BFAE_RS01185
uniprot id: C7MG03
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

446465:BFAE RS09565
gene id: 446465:BFAE_RS09565
uniprot id: C7MDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

446465:BFAE RS09990
gene id: 446465:BFAE_RS09990
uniprot id: C7ME18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07545
gene id: 446465:BFAE_RS07545
uniprot id: C7MCP9
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

446465:BFAE RS07295
gene id: 446465:BFAE_RS07295
uniprot id: C7MCK1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS15520
gene id: 446465:BFAE_RS15520
uniprot id: C7MB01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

446465:BFAE RS09140
gene id: 446465:BFAE_RS09140
uniprot id: C7MDK9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446465:BFAE RS00415
gene id: 446465:BFAE_RS00415
uniprot id: C7MF67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS09765
gene id: 446465:BFAE_RS09765
uniprot id: C7MDX6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

446465:BFAE RS03270
gene id: 446465:BFAE_RS03270
uniprot id: C7MIA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446465:BFAE RS08290
gene id: 446465:BFAE_RS08290
uniprot id: C7MD43
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

446465:BFAE RS07790
gene id: 446465:BFAE_RS07790
uniprot id: C7MCU6
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

446465:BFAE RS15855
gene id: 446465:BFAE_RS15855
uniprot id: C7MBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

446465:BFAE RS03005
gene id: 446465:BFAE_RS03005
uniprot id: C7MI50
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

446465:BFAE RS08580
gene id: 446465:BFAE_RS08580
uniprot id: C7MD99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

446465:BFAE RS08890
gene id: 446465:BFAE_RS08890
uniprot id: C7MDG0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

446465:BFAE RS07775
gene id: 446465:BFAE_RS07775
uniprot id: C7MCU3
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS00035
gene id: 446465:BFAE_RS00035
uniprot id: C7MEL3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

446465:BFAE RS05015
gene id: 446465:BFAE_RS05015
uniprot id: C7MB91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

446465:BFAE RS05035
gene id: 446465:BFAE_RS05035
uniprot id: C7MB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

446465:BFAE RS12345
gene id: 446465:BFAE_RS12345
uniprot id: C7MFQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

446465:BFAE RS04945
gene id: 446465:BFAE_RS04945
uniprot id: C7MB77
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

446465:BFAE RS13805
gene id: 446465:BFAE_RS13805
uniprot id: C7MHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS07815
gene id: 446465:BFAE_RS07815
uniprot id: C7MCV1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446465:BFAE RS01845
gene id: 446465:BFAE_RS01845
uniprot id: C7MGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

446465:BFAE RS00840
gene id: 446465:BFAE_RS00840
uniprot id: C7MFT3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

446465:BFAE RS02305
gene id: 446465:BFAE_RS02305
uniprot id: C7MHD0
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS01875
gene id: 446465:BFAE_RS01875
uniprot id: C7MGR5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

446465:BFAE RS15015
gene id: 446465:BFAE_RS15015
uniprot id: C7MAB8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446465:BFAE RS11645
gene id: 446465:BFAE_RS11645
uniprot id: C7MEZ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

446465:BFAE RS13555
gene id: 446465:BFAE_RS13555
uniprot id: C7MH54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

446465:BFAE RS03580
gene id: 446465:BFAE_RS03580
uniprot id: C7M9P3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

446465:BFAE RS07635
gene id: 446465:BFAE_RS07635
uniprot id: C7MCR7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446465:BFAE RS06180
gene id: 446465:BFAE_RS06180
uniprot id: C7MBY9
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

446465:BFAE RS11815
gene id: 446465:BFAE_RS11815
uniprot id: C7MFF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07280
gene id: 446465:BFAE_RS07280
uniprot id: C7MCJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS11230
gene id: 446465:BFAE_RS11230
uniprot id: C7MER2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

446465:BFAE RS10155
gene id: 446465:BFAE_RS10155
uniprot id: C7ME50
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446465:BFAE RS15675
gene id: 446465:BFAE_RS15675
uniprot id: C7MB32
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS03940
gene id: 446465:BFAE_RS03940
uniprot id: C7M9W2
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS15045
gene id: 446465:BFAE_RS15045
uniprot id: C7MAC4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS11600
gene id: 446465:BFAE_RS11600
uniprot id: C7MEY3
names: Similarity
messages: Belongs to the pirin family.

446465:BFAE RS05940
gene id: 446465:BFAE_RS05940
uniprot id: C7MBU1
names: Similarity
messages: Belongs to the PrpD family.

446465:BFAE RS04035
gene id: 446465:BFAE_RS04035
uniprot id: C7M9Y1
names: Similarity
messages: Belongs to the malic enzymes family.

446465:BFAE RS07190
gene id: 446465:BFAE_RS07190
uniprot id: C7MCI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446465:BFAE RS12735
gene id: 446465:BFAE_RS12735
uniprot id: C7MGB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

446465:BFAE RS11670
gene id: 446465:BFAE_RS11670
uniprot id: C7MFD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

446465:BFAE RS06525
gene id: 446465:BFAE_RS06525
uniprot id: C7MC57
names: Similarity
messages: Belongs to the disproportionating enzyme family.

446465:BFAE RS12955
gene id: 446465:BFAE_RS12955
uniprot id: C7MGF4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

446465:BFAE RS06665
gene id: 446465:BFAE_RS06665
uniprot id: C7MC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

446465:BFAE RS09020
gene id: 446465:BFAE_RS09020
uniprot id: C7MDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

446465:BFAE RS05665
gene id: 446465:BFAE_RS05665
uniprot id: C7MBN7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

446465:BFAE RS15235
gene id: 446465:BFAE_RS15235
uniprot id: C7MAU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

446465:BFAE RS04060
gene id: 446465:BFAE_RS04060
uniprot id: C7M9Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

446465:BFAE RS02480
gene id: 446465:BFAE_RS02480
uniprot id: C7MHG4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

446465:BFAE RS10595
gene id: 446465:BFAE_RS10595
uniprot id: C7MED8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

446465:BFAE RS05325
gene id: 446465:BFAE_RS05325
uniprot id: C7MBF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

446465:BFAE RS11745
gene id: 446465:BFAE_RS11745
uniprot id: C7MFE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

446465:BFAE RS14845
gene id: 446465:BFAE_RS14845
uniprot id: C7MA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

446465:BFAE RS09295
gene id: 446465:BFAE_RS09295
uniprot id: C7MDN7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

446465:BFAE RS10435
gene id: 446465:BFAE_RS10435
uniprot id: C7MEA6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

446465:BFAE RS05400
gene id: 446465:BFAE_RS05400
uniprot id: C7MBG9
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

446465:BFAE RS07960
gene id: 446465:BFAE_RS07960
uniprot id: C7MCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

446465:BFAE RS11755
gene id: 446465:BFAE_RS11755
uniprot id: C7MFE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

446465:BFAE RS10565
gene id: 446465:BFAE_RS10565
uniprot id: C7MED2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

446465:BFAE RS06975
gene id: 446465:BFAE_RS06975
uniprot id: C7MCD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

446465:BFAE RS09720
gene id: 446465:BFAE_RS09720
uniprot id: C7MDW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

446465:BFAE RS01640
gene id: 446465:BFAE_RS01640
uniprot id: C7MGL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

446465:BFAE RS12585
gene id: 446465:BFAE_RS12585
uniprot id: C7MG83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446465:BFAE RS05020
gene id: 446465:BFAE_RS05020
uniprot id: C7MB92
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

446465:BFAE RS14500
gene id: 446465:BFAE_RS14500
uniprot id: C7MA15
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446465:BFAE RS08410
gene id: 446465:BFAE_RS08410
uniprot id: C7MD65
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS06900
gene id: 446465:BFAE_RS06900
uniprot id: C7MCC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446465:BFAE RS09470
gene id: 446465:BFAE_RS09470
uniprot id: C7MDS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

446465:BFAE RS10840
gene id: 446465:BFAE_RS10840
uniprot id: C7MEI1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446465:BFAE RS14135
gene id: 446465:BFAE_RS14135
uniprot id: C7MHU7
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS05295
gene id: 446465:BFAE_RS05295
uniprot id: C7MBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

446465:BFAE RS00545
gene id: 446465:BFAE_RS00545
uniprot id: C7MF93
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

446465:BFAE RS05200
gene id: 446465:BFAE_RS05200
uniprot id: C7MBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

446465:BFAE RS10755
gene id: 446465:BFAE_RS10755
uniprot id: C7MEG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

446465:BFAE RS09080
gene id: 446465:BFAE_RS09080
uniprot id: C7MDJ7
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

446465:BFAE RS14255
gene id: 446465:BFAE_RS14255
uniprot id: C7MHX0
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS05350
gene id: 446465:BFAE_RS05350
uniprot id: C7MBF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

446465:BFAE RS00405
gene id: 446465:BFAE_RS00405
uniprot id: C7MF65
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

446465:BFAE RS06745
gene id: 446465:BFAE_RS06745
uniprot id: C7MC97
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

446465:BFAE RS15825
gene id: 446465:BFAE_RS15825
uniprot id: C7MBJ5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

446465:BFAE RS15745
gene id: 446465:BFAE_RS15745
uniprot id: C7MB44
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS06105
gene id: 446465:BFAE_RS06105
uniprot id: C7MBX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446465:BFAE RS07550
gene id: 446465:BFAE_RS07550
uniprot id: C7MCQ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

446465:BFAE RS06815
gene id: 446465:BFAE_RS06815
uniprot id: C7MCB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

446465:BFAE RS01605
gene id: 446465:BFAE_RS01605
uniprot id: C7MGL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

446465:BFAE RS06940
gene id: 446465:BFAE_RS06940
uniprot id: C7MCD0
names: Similarity
messages: Belongs to the DEAD box helicase family.

446465:BFAE RS08140
gene id: 446465:BFAE_RS08140
uniprot id: C7MD15
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

446465:BFAE RS10975
gene id: 446465:BFAE_RS10975
uniprot id: C7MEL5
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS08010
gene id: 446465:BFAE_RS08010
uniprot id: C7MCZ0
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

446465:BFAE RS06660
gene id: 446465:BFAE_RS06660
uniprot id: C7MC83
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS02510
gene id: 446465:BFAE_RS02510
uniprot id: C7MHH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS02945
gene id: 446465:BFAE_RS02945
uniprot id: C7MI38
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446465:BFAE RS09035
gene id: 446465:BFAE_RS09035
uniprot id: C7MDI8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

446465:BFAE RS03490
gene id: 446465:BFAE_RS03490
uniprot id: C7M9M5
names: Subcellular Location Annotation
messages: Cytoplasm

446465:BFAE RS11690
gene id: 446465:BFAE_RS11690
uniprot id: C7MFD4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446465:BFAE RS08685
gene id: 446465:BFAE_RS08685
uniprot id: C7MDC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

446465:BFAE RS07005
gene id: 446465:BFAE_RS07005
uniprot id: C7MCE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS14395
gene id: 446465:BFAE_RS14395
uniprot id: C7MHZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS09930
gene id: 446465:BFAE_RS09930
uniprot id: C7ME06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

446465:BFAE RS03095
gene id: 446465:BFAE_RS03095
uniprot id: C7MI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS04335
gene id: 446465:BFAE_RS04335
uniprot id: C7MAH6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

446465:BFAE RS00480
gene id: 446465:BFAE_RS00480
uniprot id: C7MF80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

446465:BFAE RS11165
gene id: 446465:BFAE_RS11165
uniprot id: C7MEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

446465:BFAE RS07965
gene id: 446465:BFAE_RS07965
uniprot id: C7MCY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

446465:BFAE RS05415
gene id: 446465:BFAE_RS05415
uniprot id: C7MBH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS12115
gene id: 446465:BFAE_RS12115
uniprot id: C7MFL6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

446465:BFAE RS05355
gene id: 446465:BFAE_RS05355
uniprot id: C7MBG0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

446465:BFAE RS15275
gene id: 446465:BFAE_RS15275
uniprot id: C7MAV2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

446465:BFAE RS07265
gene id: 446465:BFAE_RS07265
uniprot id: C7MCJ5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

446465:BFAE RS02385
gene id: 446465:BFAE_RS02385
uniprot id: C7MHE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07985
gene id: 446465:BFAE_RS07985
uniprot id: C7MCY5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

446465:BFAE RS04280
gene id: 446465:BFAE_RS04280
uniprot id: C7MAG5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

446465:BFAE RS15615
gene id: 446465:BFAE_RS15615
uniprot id: C7MB20
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

446465:BFAE RS15195
gene id: 446465:BFAE_RS15195
uniprot id: C7MAT7
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS02325
gene id: 446465:BFAE_RS02325
uniprot id: C7MHD4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

446465:BFAE RS07330
gene id: 446465:BFAE_RS07330
uniprot id: C7MCK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS00615
gene id: 446465:BFAE_RS00615
uniprot id: C7MFA7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS03460
gene id: 446465:BFAE_RS03460
uniprot id: C7M9L9
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

446465:BFAE RS08090
gene id: 446465:BFAE_RS08090
uniprot id: C7MD05
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

446465:BFAE RS10855
gene id: 446465:BFAE_RS10855
uniprot id: C7MEI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

446465:BFAE RS03850
gene id: 446465:BFAE_RS03850
uniprot id: C7M9U6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446465:BFAE RS05410
gene id: 446465:BFAE_RS05410
uniprot id: C7MBH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS03450
gene id: 446465:BFAE_RS03450
uniprot id: C7M9L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

446465:BFAE RS05495
gene id: 446465:BFAE_RS05495
uniprot id: C7MBI7
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446465:BFAE RS15810
gene id: 446465:BFAE_RS15810
uniprot id: C7MBJ2
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS10775
gene id: 446465:BFAE_RS10775
uniprot id: C7MEG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

446465:BFAE RS04205
gene id: 446465:BFAE_RS04205
uniprot id: C7MAF0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.

446465:BFAE RS03760
gene id: 446465:BFAE_RS03760
uniprot id: C7M9S8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS04640
gene id: 446465:BFAE_RS04640
uniprot id: C7MAN6
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS03675
gene id: 446465:BFAE_RS03675
uniprot id: C7M9R2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

446465:BFAE RS04110
gene id: 446465:BFAE_RS04110
uniprot id: C7M9Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS11655
gene id: 446465:BFAE_RS11655
uniprot id: C7MEZ4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

446465:BFAE RS15590
gene id: 446465:BFAE_RS15590
uniprot id: C7MB15
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

446465:BFAE RS06020
gene id: 446465:BFAE_RS06020
uniprot id: C7MBV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS00830
gene id: 446465:BFAE_RS00830
uniprot id: C7MFT1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS00115
gene id: 446465:BFAE_RS00115
uniprot id: C7MF09
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446465:BFAE RS01260
gene id: 446465:BFAE_RS01260
uniprot id: C7MG17
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS06605
gene id: 446465:BFAE_RS06605
uniprot id: C7MC73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

446465:BFAE RS07500
gene id: 446465:BFAE_RS07500
uniprot id: C7MCP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

446465:BFAE RS03780
gene id: 446465:BFAE_RS03780
uniprot id: C7M9T2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

446465:BFAE RS01305
gene id: 446465:BFAE_RS01305
uniprot id: C7MG26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

446465:BFAE RS04785
gene id: 446465:BFAE_RS04785
uniprot id: C7MAR1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

446465:BFAE RS05075
gene id: 446465:BFAE_RS05075
uniprot id: C7MBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

446465:BFAE RS04405
gene id: 446465:BFAE_RS04405
uniprot id: C7MAJ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

446465:BFAE RS07200
gene id: 446465:BFAE_RS07200
uniprot id: C7MCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

446465:BFAE RS11500
gene id: 446465:BFAE_RS11500
uniprot id: C7MEW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

446465:BFAE RS15310
gene id: 446465:BFAE_RS15310
uniprot id: C7MAV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS05365
gene id: 446465:BFAE_RS05365
uniprot id: C7MBG2
names: Similarity
messages: Belongs to the YggT family.

446465:BFAE RS01085
gene id: 446465:BFAE_RS01085
uniprot id: C7MFY3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446465:BFAE RS08775
gene id: 446465:BFAE_RS08775
uniprot id: C7MDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS02675
gene id: 446465:BFAE_RS02675
uniprot id: C7MHK1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

446465:BFAE RS11390
gene id: 446465:BFAE_RS11390
uniprot id: C7MEU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

446465:BFAE RS04615
gene id: 446465:BFAE_RS04615
uniprot id: C7MAN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

446465:BFAE RS04605
gene id: 446465:BFAE_RS04605
uniprot id: C7MAM9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS14025
gene id: 446465:BFAE_RS14025
uniprot id: C7MHS5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446465:BFAE RS06885
gene id: 446465:BFAE_RS06885
uniprot id: C7MCB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

446465:BFAE RS06435
gene id: 446465:BFAE_RS06435
uniprot id: C7MC40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446465:BFAE RS08085
gene id: 446465:BFAE_RS08085
uniprot id: C7MD04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

446465:BFAE RS00015
gene id: 446465:BFAE_RS00015
uniprot id: C7MEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

446465:BFAE RS06260
gene id: 446465:BFAE_RS06260
uniprot id: C7MC05
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

446465:BFAE RS09475
gene id: 446465:BFAE_RS09475
uniprot id: C7MDS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

446465:BFAE RS08555
gene id: 446465:BFAE_RS08555
uniprot id: C7MD94
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

446465:BFAE RS03220
gene id: 446465:BFAE_RS03220
uniprot id: C7MI94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

446465:BFAE RS02890
gene id: 446465:BFAE_RS02890
uniprot id: C7MI27
names: Similarity
messages: Belongs to the peptidase S33 family.

446465:BFAE RS10520
gene id: 446465:BFAE_RS10520
uniprot id: C7MEC3
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

446465:BFAE RS09450
gene id: 446465:BFAE_RS09450
uniprot id: C7MDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

446465:BFAE RS09985
gene id: 446465:BFAE_RS09985
uniprot id: C7ME17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS14105
gene id: 446465:BFAE_RS14105
uniprot id: C7MHU1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

446465:BFAE RS12220
gene id: 446465:BFAE_RS12220
uniprot id: C7MFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS11650
gene id: 446465:BFAE_RS11650
uniprot id: C7MEZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446465:BFAE RS11435
gene id: 446465:BFAE_RS11435
uniprot id: C7MEV0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

446465:BFAE RS11235
gene id: 446465:BFAE_RS11235
uniprot id: C7MER3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

446465:BFAE RS05630
gene id: 446465:BFAE_RS05630
uniprot id: C7MBM9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446465:BFAE RS14075
gene id: 446465:BFAE_RS14075
uniprot id: C7MHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS01785
gene id: 446465:BFAE_RS01785
uniprot id: C7MGP8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS06575
gene id: 446465:BFAE_RS06575
uniprot id: C7MC68
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

446465:BFAE RS04315
gene id: 446465:BFAE_RS04315
uniprot id: C7MAH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

446465:BFAE RS10380
gene id: 446465:BFAE_RS10380
uniprot id: C7ME95
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

446465:BFAE RS03560
gene id: 446465:BFAE_RS03560
uniprot id: C7M9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS08670
gene id: 446465:BFAE_RS08670
uniprot id: C7MDB7
names: Similarity
messages: Belongs to the UDPGP type 1 family.

446465:BFAE RS11800
gene id: 446465:BFAE_RS11800
uniprot id: C7MFF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

446465:BFAE RS12315
gene id: 446465:BFAE_RS12315
uniprot id: C7MFQ0
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

446465:BFAE RS11210
gene id: 446465:BFAE_RS11210
uniprot id: C7MEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

446465:BFAE RS02000
gene id: 446465:BFAE_RS02000
uniprot id: C7MGU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS00950
gene id: 446465:BFAE_RS00950
uniprot id: C7MFV6
names: Similarity
messages: Belongs to the FBPase class 2 family.

446465:BFAE RS11420
gene id: 446465:BFAE_RS11420
uniprot id: C7MEU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS01420
gene id: 446465:BFAE_RS01420
uniprot id: C7MGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

446465:BFAE RS09130
gene id: 446465:BFAE_RS09130
uniprot id: C7MDK7
names: Similarity
messages: Belongs to the peptidase S51 family.

446465:BFAE RS11865
gene id: 446465:BFAE_RS11865
uniprot id: C7MFG9
names: Similarity
messages: Belongs to the peptidase S8 family.

446465:BFAE RS06520
gene id: 446465:BFAE_RS06520
uniprot id: C7MC56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

446465:BFAE RS04750
gene id: 446465:BFAE_RS04750
uniprot id: C7MAQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

446465:BFAE RS01330
gene id: 446465:BFAE_RS01330
uniprot id: C7MG31
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

446465:BFAE RS07505
gene id: 446465:BFAE_RS07505
uniprot id: C7MCP1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

446465:BFAE RS06905
gene id: 446465:BFAE_RS06905
uniprot id: C7MCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446465:BFAE RS08035
gene id: 446465:BFAE_RS08035
uniprot id: C7MCZ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

446465:BFAE RS03575
gene id: 446465:BFAE_RS03575
uniprot id: C7M9P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

446465:BFAE RS13490
gene id: 446465:BFAE_RS13490
uniprot id: C7MH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS13280
gene id: 446465:BFAE_RS13280
uniprot id: C7MH01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

446465:BFAE RS10910
gene id: 446465:BFAE_RS10910
uniprot id: C7MEJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

446465:BFAE RS00560
gene id: 446465:BFAE_RS00560
uniprot id: C7MF96
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

446465:BFAE RS02175
gene id: 446465:BFAE_RS02175
uniprot id: C7MHA7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

446465:BFAE RS07570
gene id: 446465:BFAE_RS07570
uniprot id: C7MCQ4
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

446465:BFAE RS09270
gene id: 446465:BFAE_RS09270
uniprot id: C7MDN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

446465:BFAE RS11705
gene id: 446465:BFAE_RS11705
uniprot id: C7MFD7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

446465:BFAE RS10825
gene id: 446465:BFAE_RS10825
uniprot id: C7MEH8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

446465:BFAE RS11700
gene id: 446465:BFAE_RS11700
uniprot id: C7MFD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

446465:BFAE RS12510
gene id: 446465:BFAE_RS12510
uniprot id: C7MG69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446465:BFAE RS08520
gene id: 446465:BFAE_RS08520
uniprot id: C7MD87
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS10065
gene id: 446465:BFAE_RS10065
uniprot id: C7ME32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

446465:BFAE RS07925
gene id: 446465:BFAE_RS07925
uniprot id: C7MCX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

446465:BFAE RS06465
gene id: 446465:BFAE_RS06465
uniprot id: C7MC46
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

446465:BFAE RS12320
gene id: 446465:BFAE_RS12320
uniprot id: C7MFQ1
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

446465:BFAE RS05145
gene id: 446465:BFAE_RS05145
uniprot id: C7MBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

446465:BFAE RS04055
gene id: 446465:BFAE_RS04055
uniprot id: C7M9Y5
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

446465:BFAE RS15780
gene id: 446465:BFAE_RS15780
uniprot id: C7MB51
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS10510
gene id: 446465:BFAE_RS10510
uniprot id: C7MEC1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446465:BFAE RS12065
gene id: 446465:BFAE_RS12065
uniprot id: C7MFK7
names: Similarity
messages: Belongs to the histone deacetylase family.

446465:BFAE RS10545
gene id: 446465:BFAE_RS10545
uniprot id: C7MEC8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

446465:BFAE RS09480
gene id: 446465:BFAE_RS09480
uniprot id: C7MDS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

446465:BFAE RS14735
gene id: 446465:BFAE_RS14735
uniprot id: C7MA62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS05360
gene id: 446465:BFAE_RS05360
uniprot id: C7MBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

446465:BFAE RS09585
gene id: 446465:BFAE_RS09585
uniprot id: C7MDU5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

446465:BFAE RS08030
gene id: 446465:BFAE_RS08030
uniprot id: C7MCZ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

446465:BFAE RS15305
gene id: 446465:BFAE_RS15305
uniprot id: C7MAV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS12395
gene id: 446465:BFAE_RS12395
uniprot id: C7MG50
names: Similarity
messages: Belongs to the catalase family.

446465:BFAE RS06895
gene id: 446465:BFAE_RS06895
uniprot id: C7MCC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

446465:BFAE RS08855
gene id: 446465:BFAE_RS08855
uniprot id: C7MDF3
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

446465:BFAE RS00890
gene id: 446465:BFAE_RS00890
uniprot id: C7MFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS00720
gene id: 446465:BFAE_RS00720
uniprot id: C7MFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

446465:BFAE RS07660
gene id: 446465:BFAE_RS07660
uniprot id: C7MCS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

446465:BFAE RS04780
gene id: 446465:BFAE_RS04780
uniprot id: C7MAR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

446465:BFAE RS00250
gene id: 446465:BFAE_RS00250
uniprot id: C7MF36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS02255
gene id: 446465:BFAE_RS02255
uniprot id: C7MHC0
names: Similarity
messages: Belongs to the RutC family.

446465:BFAE RS09305
gene id: 446465:BFAE_RS09305
uniprot id: C7MDN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

446465:BFAE RS10495
gene id: 446465:BFAE_RS10495
uniprot id: C7MEB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

446465:BFAE RS07235
gene id: 446465:BFAE_RS07235
uniprot id: C7MCI9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

446465:BFAE RS07975
gene id: 446465:BFAE_RS07975
uniprot id: C7MCY3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

446465:BFAE RS09325
gene id: 446465:BFAE_RS09325
uniprot id: C7MDP3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446465:BFAE RS05935
gene id: 446465:BFAE_RS05935
uniprot id: C7MBU0
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

446465:BFAE RS11985
gene id: 446465:BFAE_RS11985
uniprot id: C7MFJ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS06565
gene id: 446465:BFAE_RS06565
uniprot id: C7MC65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

446465:BFAE RS08755
gene id: 446465:BFAE_RS08755
uniprot id: C7MDD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS00390
gene id: 446465:BFAE_RS00390
uniprot id: C7MF62
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

446465:BFAE RS06320
gene id: 446465:BFAE_RS06320
uniprot id: C7MC17
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

446465:BFAE RS02005
gene id: 446465:BFAE_RS02005
uniprot id: C7MGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS13070
gene id: 446465:BFAE_RS13070
uniprot id: C7MGW1
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

446465:BFAE RS04010
gene id: 446465:BFAE_RS04010
uniprot id: C7M9X6
names: Similarity
messages: Belongs to the HIBADH-related family.

446465:BFAE RS00735
gene id: 446465:BFAE_RS00735
uniprot id: C7MFR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS15755
gene id: 446465:BFAE_RS15755
uniprot id: C7MB46
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

446465:BFAE RS01355
gene id: 446465:BFAE_RS01355
uniprot id: C7MG36
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446465:BFAE RS03855
gene id: 446465:BFAE_RS03855
uniprot id: C7M9U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

446465:BFAE RS11905
gene id: 446465:BFAE_RS11905
uniprot id: C7MFH6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446465:BFAE RS00655
gene id: 446465:BFAE_RS00655
uniprot id: C7MFB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS09345
gene id: 446465:BFAE_RS09345
uniprot id: C7MDP7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

446465:BFAE RS01340
gene id: 446465:BFAE_RS01340
uniprot id: C7MG33
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

446465:BFAE RS15020
gene id: 446465:BFAE_RS15020
uniprot id: C7MAB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446465:BFAE RS09290
gene id: 446465:BFAE_RS09290
uniprot id: C7MDN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS06620
gene id: 446465:BFAE_RS06620
uniprot id: C7MC75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

446465:BFAE RS07075
gene id: 446465:BFAE_RS07075
uniprot id: C7MCF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

446465:BFAE RS01030
gene id: 446465:BFAE_RS01030
uniprot id: C7MFX2
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS00685
gene id: 446465:BFAE_RS00685
uniprot id: C7MFC0
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

446465:BFAE RS01620
gene id: 446465:BFAE_RS01620
uniprot id: C7MGL5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

446465:BFAE RS01000
gene id: 446465:BFAE_RS01000
uniprot id: C7MFW6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

446465:BFAE RS07245
gene id: 446465:BFAE_RS07245
uniprot id: C7MCJ1
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

446465:BFAE RS15230
gene id: 446465:BFAE_RS15230
uniprot id: C7MAU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

446465:BFAE RS08515
gene id: 446465:BFAE_RS08515
uniprot id: C7MD86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

446465:BFAE RS04865
gene id: 446465:BFAE_RS04865
uniprot id: C7MB62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

446465:BFAE RS10735
gene id: 446465:BFAE_RS10735
uniprot id: C7MEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS00810
gene id: 446465:BFAE_RS00810
uniprot id: C7MFS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS08120
gene id: 446465:BFAE_RS08120
uniprot id: C7MD11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

446465:BFAE RS00835
gene id: 446465:BFAE_RS00835
uniprot id: C7MFT2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS05030
gene id: 446465:BFAE_RS05030
uniprot id: C7MB95
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS11225
gene id: 446465:BFAE_RS11225
uniprot id: C7MER1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

446465:BFAE RS04380
gene id: 446465:BFAE_RS04380
uniprot id: C7MAI5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

446465:BFAE RS11485
gene id: 446465:BFAE_RS11485
uniprot id: C7MEW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS00125
gene id: 446465:BFAE_RS00125
uniprot id: C7MF11
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

446465:BFAE RS12560
gene id: 446465:BFAE_RS12560
uniprot id: C7MG78
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446465:BFAE RS08935
gene id: 446465:BFAE_RS08935
uniprot id: C7MDG9
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS09155
gene id: 446465:BFAE_RS09155
uniprot id: C7MDL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

446465:BFAE RS10145
gene id: 446465:BFAE_RS10145
uniprot id: C7ME48
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS13545
gene id: 446465:BFAE_RS13545
uniprot id: C7MH52
names: Similarity
messages: Belongs to the thiolase-like superfamily. FabH family.

446465:BFAE RS06295
gene id: 446465:BFAE_RS06295
uniprot id: C7MC12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

446465:BFAE RS03285
gene id: 446465:BFAE_RS03285
uniprot id: C7MIA5
names: Similarity
messages: Belongs to the glutaminase family.

446465:BFAE RS11665
gene id: 446465:BFAE_RS11665
uniprot id: C7MFC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

446465:BFAE RS09310
gene id: 446465:BFAE_RS09310
uniprot id: C7MDP0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

446465:BFAE RS12675
gene id: 446465:BFAE_RS12675
uniprot id: C7MGA1
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

446465:BFAE RS07665
gene id: 446465:BFAE_RS07665
uniprot id: C7MCS2
names: Similarity
messages: Belongs to the UPF0749 family.

446465:BFAE RS12500
gene id: 446465:BFAE_RS12500
uniprot id: C7MG67
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS01715
gene id: 446465:BFAE_RS01715
uniprot id: C7MGN5
names: Similarity
messages: Belongs to the universal stress protein A family.

446465:BFAE RS05195
gene id: 446465:BFAE_RS05195
uniprot id: C7MBC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

446465:BFAE RS14070
gene id: 446465:BFAE_RS14070
uniprot id: C7MHT4
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

446465:BFAE RS14350
gene id: 446465:BFAE_RS14350
uniprot id: C7MHY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS07185
gene id: 446465:BFAE_RS07185
uniprot id: C7MCH9
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

446465:BFAE RS04545
gene id: 446465:BFAE_RS04545
uniprot id: C7MAL7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS06330
gene id: 446465:BFAE_RS06330
uniprot id: C7MC19
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

446465:BFAE RS01635
gene id: 446465:BFAE_RS01635
uniprot id: C7MGL8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

446465:BFAE RS04100
gene id: 446465:BFAE_RS04100
uniprot id: C7M9Z3
names: Similarity
messages: Belongs to the DapA family.

446465:BFAE RS06915
gene id: 446465:BFAE_RS06915
uniprot id: C7MCC5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

446465:BFAE RS11475
gene id: 446465:BFAE_RS11475
uniprot id: C7MEV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

446465:BFAE RS04540
gene id: 446465:BFAE_RS04540
uniprot id: C7MAL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

446465:BFAE RS14595
gene id: 446465:BFAE_RS14595
uniprot id: C7MA34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS00895
gene id: 446465:BFAE_RS00895
uniprot id: C7MFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS12795
gene id: 446465:BFAE_RS12795
uniprot id: C7MGC6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS07610
gene id: 446465:BFAE_RS07610
uniprot id: C7MCR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS08965
gene id: 446465:BFAE_RS08965
uniprot id: C7MDH5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

446465:BFAE RS06765
gene id: 446465:BFAE_RS06765
uniprot id: C7MCA1
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS00650
gene id: 446465:BFAE_RS00650
uniprot id: C7MFB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS09550
gene id: 446465:BFAE_RS09550
uniprot id: C7MDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS06970
gene id: 446465:BFAE_RS06970
uniprot id: C7MCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

446465:BFAE RS14575
gene id: 446465:BFAE_RS14575
uniprot id: C7MA30
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446465:BFAE RS11880
gene id: 446465:BFAE_RS11880
uniprot id: C7MFH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

446465:BFAE RS01630
gene id: 446465:BFAE_RS01630
uniprot id: C7MGL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

446465:BFAE RS07490
gene id: 446465:BFAE_RS07490
uniprot id: C7MCN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

446465:BFAE RS15050
gene id: 446465:BFAE_RS15050
uniprot id: C7MAC5
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

446465:BFAE RS05380
gene id: 446465:BFAE_RS05380
uniprot id: C7MBG5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

446465:BFAE RS13930
gene id: 446465:BFAE_RS13930
uniprot id: C7MHQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

446465:BFAE RS05155
gene id: 446465:BFAE_RS05155
uniprot id: C7MBC0
names: Similarity
messages: Belongs to the asparagine synthetase family.

446465:BFAE RS00010
gene id: 446465:BFAE_RS00010
uniprot id: C7MEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

446465:BFAE RS10210
gene id: 446465:BFAE_RS10210
uniprot id: C7ME61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

446465:BFAE RS10785
gene id: 446465:BFAE_RS10785
uniprot id: C7MEH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07260
gene id: 446465:BFAE_RS07260
uniprot id: C7MCJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

446465:BFAE RS04910
gene id: 446465:BFAE_RS04910
uniprot id: C7MB70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

446465:BFAE RS03890
gene id: 446465:BFAE_RS03890
uniprot id: C7M9V4
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

446465:BFAE RS04115
gene id: 446465:BFAE_RS04115
uniprot id: C7M9Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS01820
gene id: 446465:BFAE_RS01820
uniprot id: C7MGQ4
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS15545
gene id: 446465:BFAE_RS15545
uniprot id: C7MB06
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

446465:BFAE RS04885
gene id: 446465:BFAE_RS04885
uniprot id: C7MB66
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

446465:BFAE RS11050
gene id: 446465:BFAE_RS11050
uniprot id: C7MEN1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

446465:BFAE RS07415
gene id: 446465:BFAE_RS07415
uniprot id: C7MCM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

446465:BFAE RS13465
gene id: 446465:BFAE_RS13465
uniprot id: C7MH36
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446465:BFAE RS05290
gene id: 446465:BFAE_RS05290
uniprot id: C7MBE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

446465:BFAE RS15370
gene id: 446465:BFAE_RS15370
uniprot id: C7MAX1
names: Similarity
messages: Belongs to the universal stress protein A family.

446465:BFAE RS10915
gene id: 446465:BFAE_RS10915
uniprot id: C7MEJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

446465:BFAE RS07485
gene id: 446465:BFAE_RS07485
uniprot id: C7MCN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

446465:BFAE RS14610
gene id: 446465:BFAE_RS14610
uniprot id: C7MA37
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS12590
gene id: 446465:BFAE_RS12590
uniprot id: C7MG84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

446465:BFAE RS15770
gene id: 446465:BFAE_RS15770
uniprot id: C7MB49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

446465:BFAE RS03525
gene id: 446465:BFAE_RS03525
uniprot id: C7M9N2
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

446465:BFAE RS12525
gene id: 446465:BFAE_RS12525
uniprot id: C7MG72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS04250
gene id: 446465:BFAE_RS04250
uniprot id: C7MAF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

446465:BFAE RS12010
gene id: 446465:BFAE_RS12010
uniprot id: C7MFJ7
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS12650
gene id: 446465:BFAE_RS12650
uniprot id: C7MG96
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS05685
gene id: 446465:BFAE_RS05685
uniprot id: C7MBP1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

446465:BFAE RS05110
gene id: 446465:BFAE_RS05110
uniprot id: C7MBB1
names: Similarity
messages: Belongs to the ribF family.

446465:BFAE RS05475
gene id: 446465:BFAE_RS05475
uniprot id: C7MBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

446465:BFAE RS14910
gene id: 446465:BFAE_RS14910
uniprot id: C7MA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS04940
gene id: 446465:BFAE_RS04940
uniprot id: C7MB76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

446465:BFAE RS11520
gene id: 446465:BFAE_RS11520
uniprot id: C7MEW7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

446465:BFAE RS00990
gene id: 446465:BFAE_RS00990
uniprot id: C7MFW4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

446465:BFAE RS14190
gene id: 446465:BFAE_RS14190
uniprot id: C7MHV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS06190
gene id: 446465:BFAE_RS06190
uniprot id: C7MBZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS13955
gene id: 446465:BFAE_RS13955
uniprot id: C7MHR0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

446465:BFAE RS15095
gene id: 446465:BFAE_RS15095
uniprot id: C7MAD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

446465:BFAE RS04895
gene id: 446465:BFAE_RS04895
uniprot id: C7MB68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

446465:BFAE RS08160
gene id: 446465:BFAE_RS08160
uniprot id: C7MD19
names: Similarity
messages: Belongs to the glutamine synthetase family.

446465:BFAE RS09175
gene id: 446465:BFAE_RS09175
uniprot id: C7MDL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS07300
gene id: 446465:BFAE_RS07300
uniprot id: C7MCK2
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

446465:BFAE RS10105
gene id: 446465:BFAE_RS10105
uniprot id: C7ME40
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS13885
gene id: 446465:BFAE_RS13885
uniprot id: C7MHP6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446465:BFAE RS06050
gene id: 446465:BFAE_RS06050
uniprot id: C7MBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07105
gene id: 446465:BFAE_RS07105
uniprot id: C7MCG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

446465:BFAE RS02350
gene id: 446465:BFAE_RS02350
uniprot id: C7MHD8
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

446465:BFAE RS01360
gene id: 446465:BFAE_RS01360
uniprot id: C7MG37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

446465:BFAE RS06980
gene id: 446465:BFAE_RS06980
uniprot id: C7MCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

446465:BFAE RS11810
gene id: 446465:BFAE_RS11810
uniprot id: C7MFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS07555
gene id: 446465:BFAE_RS07555
uniprot id: C7MCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

446465:BFAE RS00605
gene id: 446465:BFAE_RS00605
uniprot id: C7MFA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS04955
gene id: 446465:BFAE_RS04955
uniprot id: C7MB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

446465:BFAE RS04980
gene id: 446465:BFAE_RS04980
uniprot id: C7MB84
names: Similarity
messages: Belongs to the DprA/Smf family.

446465:BFAE RS05450
gene id: 446465:BFAE_RS05450
uniprot id: C7MBH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

446465:BFAE RS14480
gene id: 446465:BFAE_RS14480
uniprot id: C7MA11
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

446465:BFAE RS01780
gene id: 446465:BFAE_RS01780
uniprot id: C7MGP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446465:BFAE RS08060
gene id: 446465:BFAE_RS08060
uniprot id: C7MD00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS05760
gene id: 446465:BFAE_RS05760
uniprot id: C7MBQ6
names: Similarity
messages: Belongs to the FPG family.

446465:BFAE RS08610
gene id: 446465:BFAE_RS08610
uniprot id: C7MDA5
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS14355
gene id: 446465:BFAE_RS14355
uniprot id: C7MHY9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

446465:BFAE RS14850
gene id: 446465:BFAE_RS14850
uniprot id: C7MA85
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

446465:BFAE RS14530
gene id: 446465:BFAE_RS14530
uniprot id: C7MA21
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

446465:BFAE RS15140
gene id: 446465:BFAE_RS15140
uniprot id: C7MAS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446465:BFAE RS00960
gene id: 446465:BFAE_RS00960
uniprot id: C7MFV8
names: Similarity
messages: Belongs to the peptidase M20A family.

446465:BFAE RS11805
gene id: 446465:BFAE_RS11805
uniprot id: C7MFF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

446465:BFAE RS13855
gene id: 446465:BFAE_RS13855
uniprot id: C7MHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

446465:BFAE RS02640
gene id: 446465:BFAE_RS02640
uniprot id: C7MHJ4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

446465:BFAE RS12790
gene id: 446465:BFAE_RS12790
uniprot id: C7MGC5
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS11730
gene id: 446465:BFAE_RS11730
uniprot id: C7MFE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

446465:BFAE RS11590
gene id: 446465:BFAE_RS11590
uniprot id: C7MEY1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446465:BFAE RS12365
gene id: 446465:BFAE_RS12365
uniprot id: C7MFR0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

446465:BFAE RS04740
gene id: 446465:BFAE_RS04740
uniprot id: C7MAQ4
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

446465:BFAE RS06200
gene id: 446465:BFAE_RS06200
uniprot id: C7MBZ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

446465:BFAE RS15110
gene id: 446465:BFAE_RS15110
uniprot id: C7MAS0
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS05215
gene id: 446465:BFAE_RS05215
uniprot id: C7MBD2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446465:BFAE RS11915
gene id: 446465:BFAE_RS11915
uniprot id: C7MFH8
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

446465:BFAE RS07080
gene id: 446465:BFAE_RS07080
uniprot id: C7MCF8
names: Similarity
messages: Belongs to the universal stress protein A family.

446465:BFAE RS10610
gene id: 446465:BFAE_RS10610
uniprot id: C7MEE1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

446465:BFAE RS01115
gene id: 446465:BFAE_RS01115
uniprot id: C7MFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

446465:BFAE RS07420
gene id: 446465:BFAE_RS07420
uniprot id: C7MCM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446465:BFAE RS02530
gene id: 446465:BFAE_RS02530
uniprot id: C7MHH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell membrane

446465:BFAE RS02405
gene id: 446465:BFAE_RS02405
uniprot id: C7MHE9
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS02790
gene id: 446465:BFAE_RS02790
uniprot id: C7MI07
names: Similarity
messages: Belongs to the Dps family.

446465:BFAE RS06170
gene id: 446465:BFAE_RS06170
uniprot id: C7MBY7
names: Similarity
messages: Belongs to the HSP15 family.

446465:BFAE RS05125
gene id: 446465:BFAE_RS05125
uniprot id: C7MBB4
names: Similarity
messages: Belongs to the peptidase M16 family.

446465:BFAE RS15760
gene id: 446465:BFAE_RS15760
uniprot id: C7MB47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

446465:BFAE RS13715
gene id: 446465:BFAE_RS13715
uniprot id: C7MH82
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

446465:BFAE RS04415
gene id: 446465:BFAE_RS04415
uniprot id: C7MAJ2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

446465:BFAE RS09050
gene id: 446465:BFAE_RS09050
uniprot id: C7MDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

446465:BFAE RS03215
gene id: 446465:BFAE_RS03215
uniprot id: C7MI93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

446465:BFAE RS04610
gene id: 446465:BFAE_RS04610
uniprot id: C7MAN0
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

446465:BFAE RS04760
gene id: 446465:BFAE_RS04760
uniprot id: C7MAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

446465:BFAE RS00150
gene id: 446465:BFAE_RS00150
uniprot id: C7MF16
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS06680
gene id: 446465:BFAE_RS06680
uniprot id: C7MC87
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

446465:BFAE RS05500
gene id: 446465:BFAE_RS05500
uniprot id: C7MBI8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446465:BFAE RS11660
gene id: 446465:BFAE_RS11660
uniprot id: C7MEZ5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

446465:BFAE RS07290
gene id: 446465:BFAE_RS07290
uniprot id: C7MCK0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

446465:BFAE RS07115
gene id: 446465:BFAE_RS07115
uniprot id: C7MCG5
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

446465:BFAE RS06210
gene id: 446465:BFAE_RS06210
uniprot id: C7MBZ5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

446465:BFAE RS07575
gene id: 446465:BFAE_RS07575
uniprot id: C7MCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

446465:BFAE RS03565
gene id: 446465:BFAE_RS03565
uniprot id: C7M9P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS10110
gene id: 446465:BFAE_RS10110
uniprot id: C7ME41
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS04925
gene id: 446465:BFAE_RS04925
uniprot id: C7MB73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

446465:BFAE RS15415
gene id: 446465:BFAE_RS15415
uniprot id: C7MAY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS03750
gene id: 446465:BFAE_RS03750
uniprot id: C7M9S6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

446465:BFAE RS09010
gene id: 446465:BFAE_RS09010
uniprot id: C7MDI3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

446465:BFAE RS03945
gene id: 446465:BFAE_RS03945
uniprot id: C7M9W3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446465:BFAE RS04600
gene id: 446465:BFAE_RS04600
uniprot id: C7MAM8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446465:BFAE RS15260
gene id: 446465:BFAE_RS15260
uniprot id: C7MAV0
names: Similarity
messages: Belongs to the fructosamine kinase family.

446465:BFAE RS14140
gene id: 446465:BFAE_RS14140
uniprot id: C7MHU8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS01815
gene id: 446465:BFAE_RS01815
uniprot id: C7MGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

446465:BFAE RS11155
gene id: 446465:BFAE_RS11155
uniprot id: C7MEP9
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS01395
gene id: 446465:BFAE_RS01395
uniprot id: C7MG43
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

446465:BFAE RS04590
gene id: 446465:BFAE_RS04590
uniprot id: C7MAM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

446465:BFAE RS05310
gene id: 446465:BFAE_RS05310
uniprot id: C7MBF1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS05930
gene id: 446465:BFAE_RS05930
uniprot id: C7MBT9
names: Similarity
messages: Belongs to the citrate synthase family.

446465:BFAE RS06715
gene id: 446465:BFAE_RS06715
uniprot id: C7MC91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS10815
gene id: 446465:BFAE_RS10815
uniprot id: C7MEH6
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

446465:BFAE RS02170
gene id: 446465:BFAE_RS02170
uniprot id: C7MHA6
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS02235
gene id: 446465:BFAE_RS02235
uniprot id: C7MHB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

446465:BFAE RS04340
gene id: 446465:BFAE_RS04340
uniprot id: C7MAH7
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS14570
gene id: 446465:BFAE_RS14570
uniprot id: C7MA29
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

446465:BFAE RS00535
gene id: 446465:BFAE_RS00535
uniprot id: C7MF91
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446465:BFAE RS11260
gene id: 446465:BFAE_RS11260
uniprot id: C7MER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS03600
gene id: 446465:BFAE_RS03600
uniprot id: C7M9P7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

446465:BFAE RS15345
gene id: 446465:BFAE_RS15345
uniprot id: C7MAW6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

446465:BFAE RS14860
gene id: 446465:BFAE_RS14860
uniprot id: C7MA87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

446465:BFAE RS11870
gene id: 446465:BFAE_RS11870
uniprot id: C7MFH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

446465:BFAE RS05220
gene id: 446465:BFAE_RS05220
uniprot id: C7MBD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS04000
gene id: 446465:BFAE_RS04000
uniprot id: C7M9X4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

446465:BFAE RS11720
gene id: 446465:BFAE_RS11720
uniprot id: C7MFE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

446465:BFAE RS06315
gene id: 446465:BFAE_RS06315
uniprot id: C7MC16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

446465:BFAE RS06825
gene id: 446465:BFAE_RS06825
uniprot id: C7MCB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446465:BFAE RS09385
gene id: 446465:BFAE_RS09385
uniprot id: C7MDQ5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

446465:BFAE RS04635
gene id: 446465:BFAE_RS04635
uniprot id: C7MAN5
names: Similarity
messages: Belongs to the AHA1 family.

446465:BFAE RS15120
gene id: 446465:BFAE_RS15120
uniprot id: C7MAS2
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS06300
gene id: 446465:BFAE_RS06300
uniprot id: C7MC13
names: Similarity
messages: Belongs to the peptidase S13 family.

446465:BFAE RS04825
gene id: 446465:BFAE_RS04825
uniprot id: C7MB54
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS04695
gene id: 446465:BFAE_RS04695
uniprot id: C7MAP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

446465:BFAE RS02020
gene id: 446465:BFAE_RS02020
uniprot id: C7MGU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS15070
gene id: 446465:BFAE_RS15070
uniprot id: C7MAC9
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

446465:BFAE RS07425
gene id: 446465:BFAE_RS07425
uniprot id: C7MCM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS02045
gene id: 446465:BFAE_RS02045
uniprot id: C7MGU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

446465:BFAE RS02470
gene id: 446465:BFAE_RS02470
uniprot id: C7MHG2
names: Similarity
messages: Belongs to the universal stress protein A family.

446465:BFAE RS12775
gene id: 446465:BFAE_RS12775
uniprot id: C7MGC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

446465:BFAE RS15105
gene id: 446465:BFAE_RS15105
uniprot id: C7MAR9
names: Similarity
messages: Belongs to the universal stress protein A family.

446465:BFAE RS10075
gene id: 446465:BFAE_RS10075
uniprot id: C7ME34
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

446465:BFAE RS07720
gene id: 446465:BFAE_RS07720
uniprot id: C7MCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS07655
gene id: 446465:BFAE_RS07655
uniprot id: C7MCS0
names: Similarity
messages: Belongs to the UPF0749 family.

446465:BFAE RS14050
gene id: 446465:BFAE_RS14050
uniprot id: C7MHT0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

446465:BFAE RS08130
gene id: 446465:BFAE_RS08130
uniprot id: C7MD13
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446465:BFAE RS14270
gene id: 446465:BFAE_RS14270
uniprot id: C7MHX3
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS13305
gene id: 446465:BFAE_RS13305
uniprot id: C7MH06
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

446465:BFAE RS08005
gene id: 446465:BFAE_RS08005
uniprot id: C7MCY9
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

446465:BFAE RS07530
gene id: 446465:BFAE_RS07530
uniprot id: C7MCP6
names: Function
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

446465:BFAE RS09040
gene id: 446465:BFAE_RS09040
uniprot id: C7MDI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

446465:BFAE RS12580
gene id: 446465:BFAE_RS12580
uniprot id: C7MG82
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

446465:BFAE RS15525
gene id: 446465:BFAE_RS15525
uniprot id: C7MB02
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446465:BFAE RS04170
gene id: 446465:BFAE_RS04170
uniprot id: C7MAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446465:BFAE RS12225
gene id: 446465:BFAE_RS12225
uniprot id: C7MFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS09560
gene id: 446465:BFAE_RS09560
uniprot id: C7MDU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446465:BFAE RS14655
gene id: 446465:BFAE_RS14655
uniprot id: C7MA46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

446465:BFAE RS06000
gene id: 446465:BFAE_RS06000
uniprot id: C7MBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

446465:BFAE RS15360
gene id: 446465:BFAE_RS15360
uniprot id: C7MAW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm

446465:BFAE RS07065
gene id: 446465:BFAE_RS07065
uniprot id: C7MCF5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

446465:BFAE RS09640
gene id: 446465:BFAE_RS09640
uniprot id: C7MDV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446465:BFAE RS08840
gene id: 446465:BFAE_RS08840
uniprot id: C7MDF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS00715
gene id: 446465:BFAE_RS00715
uniprot id: C7MFC6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

446465:BFAE RS07540
gene id: 446465:BFAE_RS07540
uniprot id: C7MCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

446465:BFAE RS11945
gene id: 446465:BFAE_RS11945
uniprot id: C7MFI4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

446465:BFAE RS14805
gene id: 446465:BFAE_RS14805
uniprot id: C7MA76
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

446465:BFAE RS12150
gene id: 446465:BFAE_RS12150
uniprot id: C7MFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446465:BFAE RS07950
gene id: 446465:BFAE_RS07950
uniprot id: C7MCX8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

446465:BFAE RS13850
gene id: 446465:BFAE_RS13850
uniprot id: C7MHN9
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

446465:BFAE RS05445
gene id: 446465:BFAE_RS05445
uniprot id: C7MBH8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS11055
gene id: 446465:BFAE_RS11055
uniprot id: C7MEN2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

446465:BFAE RS10275
gene id: 446465:BFAE_RS10275
uniprot id: C7ME74
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446465:BFAE RS13985
gene id: 446465:BFAE_RS13985
uniprot id: C7MHR7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446465:BFAE RS11835
gene id: 446465:BFAE_RS11835
uniprot id: C7MFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

446465:BFAE RS08880
gene id: 446465:BFAE_RS08880
uniprot id: C7MDF8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS07995
gene id: 446465:BFAE_RS07995
uniprot id: C7MCY7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

446465:BFAE RS05755
gene id: 446465:BFAE_RS05755
uniprot id: C7MBQ5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

446465:BFAE RS00495
gene id: 446465:BFAE_RS00495
uniprot id: C7MF83
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS06055
gene id: 446465:BFAE_RS06055
uniprot id: C7MBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

446465:BFAE RS06550
gene id: 446465:BFAE_RS06550
uniprot id: C7MC62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

446465:BFAE RS14810
gene id: 446465:BFAE_RS14810
uniprot id: C7MA77
names: Similarity
messages: Belongs to the FGGY kinase family.

446465:BFAE RS11555
gene id: 446465:BFAE_RS11555
uniprot id: C7MEX4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

446465:BFAE RS14460
gene id: 446465:BFAE_RS14460
uniprot id: C7MA07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

446465:BFAE RS08095
gene id: 446465:BFAE_RS08095
uniprot id: C7MD06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

446465:BFAE RS13575
gene id: 446465:BFAE_RS13575
uniprot id: C7MH56
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS07510
gene id: 446465:BFAE_RS07510
uniprot id: C7MCP2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

446465:BFAE RS01080
gene id: 446465:BFAE_RS01080
uniprot id: C7MFY2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446465:BFAE RS04960
gene id: 446465:BFAE_RS04960
uniprot id: C7MB80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

446465:BFAE RS11425
gene id: 446465:BFAE_RS11425
uniprot id: C7MEU8
names: Subcellular Location Annotation
messages: Membrane

446465:BFAE RS15405
gene id: 446465:BFAE_RS15405
uniprot id: C7MAX8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

446465:BFAE RS09425
gene id: 446465:BFAE_RS09425
uniprot id: C7MDR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

446465:BFAE RS08425
gene id: 446465:BFAE_RS08425
uniprot id: C7MD68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446465:BFAE RS00170
gene id: 446465:BFAE_RS00170
uniprot id: C7MF20
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446465:BFAE RS02285
gene id: 446465:BFAE_RS02285
uniprot id: C7MHC6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

446465:BFAE RS02195
gene id: 446465:BFAE_RS02195
uniprot id: C7MHB1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.