446462:AMIR RS06850
gene id: 446462:AMIR_RS06850
uniprot id: C6W9F5
names: Similarity
messages: Belongs to the asparagine synthetase family.

446462:AMIR RS01150
gene id: 446462:AMIR_RS01150
uniprot id: C6WF63
names: Similarity
messages: Belongs to the Dps family.

446462:AMIR RS11465
gene id: 446462:AMIR_RS11465
uniprot id: C6WII3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

446462:AMIR RS32660
gene id: 446462:AMIR_RS32660
uniprot id: C6WM07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

446462:AMIR RS07010
gene id: 446462:AMIR_RS07010
uniprot id: C6W9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

446462:AMIR RS16660
gene id: 446462:AMIR_RS16660
uniprot id: C6W9M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

446462:AMIR RS15510
gene id: 446462:AMIR_RS15510
uniprot id: C6W7Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

446462:AMIR RS00055
gene id: 446462:AMIR_RS00055
uniprot id: C6WCG3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS28005
gene id: 446462:AMIR_RS28005
uniprot id: C6WC77
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

446462:AMIR RS02220
gene id: 446462:AMIR_RS02220
uniprot id: C6WHV6
names: Subcellular Location Annotation
messages: Cytoplasm

446462:AMIR RS00745
gene id: 446462:AMIR_RS00745
uniprot id: C6WDX2
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

446462:AMIR RS15260
gene id: 446462:AMIR_RS15260
uniprot id: C6WRX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS01675
gene id: 446462:AMIR_RS01675
uniprot id: C6WGI2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS06540
gene id: 446462:AMIR_RS06540
uniprot id: C6WRK3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

446462:AMIR RS10600
gene id: 446462:AMIR_RS10600
uniprot id: C6WGZ1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS12540
gene id: 446462:AMIR_RS12540
uniprot id: C6WL91
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446462:AMIR RS24600
gene id: 446462:AMIR_RS24600
uniprot id: C6WQT9
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

446462:AMIR RS29965
gene id: 446462:AMIR_RS29965
uniprot id: C6WG88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS32595
gene id: 446462:AMIR_RS32595
uniprot id: C6WLZ3
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS30125
gene id: 446462:AMIR_RS30125
uniprot id: C6WGC1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS04005
gene id: 446462:AMIR_RS04005
uniprot id: C6WL04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

446462:AMIR RS29900
gene id: 446462:AMIR_RS29900
uniprot id: C6WG75
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

446462:AMIR RS24550
gene id: 446462:AMIR_RS24550
uniprot id: C6WQS9
names: Similarity
messages: Belongs to the SurE nucleotidase family.

446462:AMIR RS01750
gene id: 446462:AMIR_RS01750
uniprot id: C6WGJ7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

446462:AMIR RS32535
gene id: 446462:AMIR_RS32535
uniprot id: C6WLY1
names: Similarity
messages: Belongs to the WXG100 family.

446462:AMIR RS31350
gene id: 446462:AMIR_RS31350
uniprot id: C6WJ50
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

446462:AMIR RS28255
gene id: 446462:AMIR_RS28255
uniprot id: C6WCC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

446462:AMIR RS17025
gene id: 446462:AMIR_RS17025
uniprot id: C6W9U2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS16820
gene id: 446462:AMIR_RS16820
uniprot id: C6W9Q1
names: Similarity
messages: Belongs to the XFP family.

446462:AMIR RS01870
gene id: 446462:AMIR_RS01870
uniprot id: C6WGM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS26955
gene id: 446462:AMIR_RS26955
uniprot id: C6WA69
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

446462:AMIR RS24955
gene id: 446462:AMIR_RS24955
uniprot id: C6WS32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

446462:AMIR RS05815
gene id: 446462:AMIR_RS05815
uniprot id: C6WQ56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

446462:AMIR RS34400
gene id: 446462:AMIR_RS34400
uniprot id: C6WR45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

446462:AMIR RS31685
gene id: 446462:AMIR_RS31685
uniprot id: C6WKE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

446462:AMIR RS29790
gene id: 446462:AMIR_RS29790
uniprot id: C6WG52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446462:AMIR RS26615
gene id: 446462:AMIR_RS26615
uniprot id: C6WA00
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS32705
gene id: 446462:AMIR_RS32705
uniprot id: C6WM16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

446462:AMIR RS14605
gene id: 446462:AMIR_RS14605
uniprot id: C6WQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS07130
gene id: 446462:AMIR_RS07130
uniprot id: C6WAA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

446462:AMIR RS08645
gene id: 446462:AMIR_RS08645
uniprot id: C6WCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

446462:AMIR RS02270
gene id: 446462:AMIR_RS02270
uniprot id: C6WHW6
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS01655
gene id: 446462:AMIR_RS01655
uniprot id: C6WGH8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

446462:AMIR RS34545
gene id: 446462:AMIR_RS34545
uniprot id: C6WR74
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446462:AMIR RS03045
gene id: 446462:AMIR_RS03045
uniprot id: C6WJD8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

446462:AMIR RS17995
gene id: 446462:AMIR_RS17995
uniprot id: C6WBT3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS26475
gene id: 446462:AMIR_RS26475
uniprot id: C6W990
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

446462:AMIR RS05690
gene id: 446462:AMIR_RS05690
uniprot id: C6WQ33
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446462:AMIR RS32815
gene id: 446462:AMIR_RS32815
uniprot id: C6WN59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446462:AMIR RS10105
gene id: 446462:AMIR_RS10105
uniprot id: C6WFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

446462:AMIR RS27305
gene id: 446462:AMIR_RS27305
uniprot id: C6WB37
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

446462:AMIR RS01730
gene id: 446462:AMIR_RS01730
uniprot id: C6WGJ3
names: Similarity
messages: Belongs to the peptidase M1 family.

446462:AMIR RS09610
gene id: 446462:AMIR_RS09610
uniprot id: C6WEC3
names: Similarity
messages: Belongs to the XFP family.

446462:AMIR RS25660
gene id: 446462:AMIR_RS25660
uniprot id: C6W8E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446462:AMIR RS01005
gene id: 446462:AMIR_RS01005
uniprot id: C6WF37
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446462:AMIR RS33785
gene id: 446462:AMIR_RS33785
uniprot id: C6WPR1
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS29400
gene id: 446462:AMIR_RS29400
uniprot id: C6WEW6
names: Similarity
messages: Belongs to the P(II) protein family.

446462:AMIR RS18800
gene id: 446462:AMIR_RS18800
uniprot id: C6WD33
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS03350
gene id: 446462:AMIR_RS03350
uniprot id: C6WJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

446462:AMIR RS28015
gene id: 446462:AMIR_RS28015
uniprot id: C6WC79
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS21340
gene id: 446462:AMIR_RS21340
uniprot id: C6WIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446462:AMIR RS26040
gene id: 446462:AMIR_RS26040
uniprot id: C6W901
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

446462:AMIR RS01125
gene id: 446462:AMIR_RS01125
uniprot id: C6WF58
names: Similarity
messages: Belongs to the FGGY kinase family.

446462:AMIR RS32110
gene id: 446462:AMIR_RS32110
uniprot id: C6WKM8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

446462:AMIR RS00095
gene id: 446462:AMIR_RS00095
uniprot id: C6WCH2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

446462:AMIR RS27270
gene id: 446462:AMIR_RS27270
uniprot id: C6WB30
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

446462:AMIR RS32635
gene id: 446462:AMIR_RS32635
uniprot id: C6WM01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

446462:AMIR RS32785
gene id: 446462:AMIR_RS32785
uniprot id: C6WN53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

446462:AMIR RS31210
gene id: 446462:AMIR_RS31210
uniprot id: C6WJ23
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

446462:AMIR RS24425
gene id: 446462:AMIR_RS24425
uniprot id: C6WQQ4
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

446462:AMIR RS07020
gene id: 446462:AMIR_RS07020
uniprot id: C6W9I9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

446462:AMIR RS11145
gene id: 446462:AMIR_RS11145
uniprot id: C6WIC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

446462:AMIR RS18940
gene id: 446462:AMIR_RS18940
uniprot id: C6WD59
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS07490
gene id: 446462:AMIR_RS07490
uniprot id: C6WAH7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

446462:AMIR RS04960
gene id: 446462:AMIR_RS04960
uniprot id: C6WNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

446462:AMIR RS02280
gene id: 446462:AMIR_RS02280
uniprot id: C6WHW8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

446462:AMIR RS09550
gene id: 446462:AMIR_RS09550
uniprot id: C6WEB0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS34180
gene id: 446462:AMIR_RS34180
uniprot id: C6WQZ9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS02155
gene id: 446462:AMIR_RS02155
uniprot id: C6WHU3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

446462:AMIR RS03300
gene id: 446462:AMIR_RS03300
uniprot id: C6WJI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

446462:AMIR RS01585
gene id: 446462:AMIR_RS01585
uniprot id: C6WGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

446462:AMIR RS04365
gene id: 446462:AMIR_RS04365
uniprot id: C6WM99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

446462:AMIR RS11825
gene id: 446462:AMIR_RS11825
uniprot id: C6WJS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

446462:AMIR RS33250
gene id: 446462:AMIR_RS33250
uniprot id: C6WNE5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS03890
gene id: 446462:AMIR_RS03890
uniprot id: C6WKY2
names: Similarity
messages: Belongs to the LOG family.

446462:AMIR RS28670
gene id: 446462:AMIR_RS28670
uniprot id: C6WDG2
names: Similarity
messages: Belongs to the glutamine synthetase family.

446462:AMIR RS34835
gene id: 446462:AMIR_RS34835
uniprot id: C6WSF3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

446462:AMIR RS24665
gene id: 446462:AMIR_RS24665
uniprot id: C6WQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

446462:AMIR RS30440
gene id: 446462:AMIR_RS30440
uniprot id: C6WHJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

446462:AMIR RS28660
gene id: 446462:AMIR_RS28660
uniprot id: C6WDG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

446462:AMIR RS19675
gene id: 446462:AMIR_RS19675
uniprot id: C6WEL7
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS01115
gene id: 446462:AMIR_RS01115
uniprot id: C6WF56
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

446462:AMIR RS04635
gene id: 446462:AMIR_RS04635
uniprot id: C6WMF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

446462:AMIR RS17900
gene id: 446462:AMIR_RS17900
uniprot id: C6WBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

446462:AMIR RS00740
gene id: 446462:AMIR_RS00740
uniprot id: C6WDX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS14440
gene id: 446462:AMIR_RS14440
uniprot id: C6WQG1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06720
gene id: 446462:AMIR_RS06720
uniprot id: C6W9C9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

446462:AMIR RS19370
gene id: 446462:AMIR_RS19370
uniprot id: C6WEG2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS32925
gene id: 446462:AMIR_RS32925
uniprot id: C6WN80
names: Similarity
messages: Belongs to the UPF0336 family.

446462:AMIR RS04820
gene id: 446462:AMIR_RS04820
uniprot id: C6WNJ8
names: Similarity
messages: Belongs to the HsdR family.

446462:AMIR RS33040
gene id: 446462:AMIR_RS33040
uniprot id: C6WNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446462:AMIR RS06510
gene id: 446462:AMIR_RS06510
uniprot id: C6WRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

446462:AMIR RS27085
gene id: 446462:AMIR_RS27085
uniprot id: C6WA93
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

446462:AMIR RS14695
gene id: 446462:AMIR_RS14695
uniprot id: C6WRL7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

446462:AMIR RS23120
gene id: 446462:AMIR_RS23120
uniprot id: C6WMW5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS03630
gene id: 446462:AMIR_RS03630
uniprot id: C6WKS9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS26715
gene id: 446462:AMIR_RS26715
uniprot id: C6WA21
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

446462:AMIR RS00345
gene id: 446462:AMIR_RS00345
uniprot id: C6WDP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446462:AMIR RS32695
gene id: 446462:AMIR_RS32695
uniprot id: C6WM14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

446462:AMIR RS10025
gene id: 446462:AMIR_RS10025
uniprot id: C6WFL5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

446462:AMIR RS29335
gene id: 446462:AMIR_RS29335
uniprot id: C6WEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

446462:AMIR RS25800
gene id: 446462:AMIR_RS25800
uniprot id: C6W8H7
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

446462:AMIR RS34880
gene id: 446462:AMIR_RS34880
uniprot id: C6WSG2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS29355
gene id: 446462:AMIR_RS29355
uniprot id: C6WEV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

446462:AMIR RS11975
gene id: 446462:AMIR_RS11975
uniprot id: C6WJV5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS20945
gene id: 446462:AMIR_RS20945
uniprot id: C6WHE2
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

446462:AMIR RS07185
gene id: 446462:AMIR_RS07185
uniprot id: C6WAB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

446462:AMIR RS11110
gene id: 446462:AMIR_RS11110
uniprot id: C6WIB5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS27050
gene id: 446462:AMIR_RS27050
uniprot id: C6WA86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

446462:AMIR RS02525
gene id: 446462:AMIR_RS02525
uniprot id: C6WI17
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS25080
gene id: 446462:AMIR_RS25080
uniprot id: C6WS59
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS29210
gene id: 446462:AMIR_RS29210
uniprot id: C6WES9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS07015
gene id: 446462:AMIR_RS07015
uniprot id: C6W9I8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

446462:AMIR RS09670
gene id: 446462:AMIR_RS09670
uniprot id: C6WFE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

446462:AMIR RS34820
gene id: 446462:AMIR_RS34820
uniprot id: C6WSF0
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS34305
gene id: 446462:AMIR_RS34305
uniprot id: C6WR26
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

446462:AMIR RS31965
gene id: 446462:AMIR_RS31965
uniprot id: C6WKJ9
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

446462:AMIR RS22395
gene id: 446462:AMIR_RS22395
uniprot id: C6WLF0
names: Similarity
messages: Belongs to the threonine aldolase family.

446462:AMIR RS20875
gene id: 446462:AMIR_RS20875
uniprot id: C6WHC7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446462:AMIR RS34890
gene id: 446462:AMIR_RS34890
uniprot id: C6WSG4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

446462:AMIR RS05440
gene id: 446462:AMIR_RS05440
uniprot id: C6WPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

446462:AMIR RS27150
gene id: 446462:AMIR_RS27150
uniprot id: C6WB04
names: Similarity
messages: Belongs to the RutC family.

446462:AMIR RS33335
gene id: 446462:AMIR_RS33335
uniprot id: C6WNG2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

446462:AMIR RS19115
gene id: 446462:AMIR_RS19115
uniprot id: C6WD94
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

446462:AMIR RS25715
gene id: 446462:AMIR_RS25715
uniprot id: C6W8F9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

446462:AMIR RS06645
gene id: 446462:AMIR_RS06645
uniprot id: C6W9B4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

446462:AMIR RS25970
gene id: 446462:AMIR_RS25970
uniprot id: C6W8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

446462:AMIR RS09110
gene id: 446462:AMIR_RS09110
uniprot id: C6WE21
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446462:AMIR RS35080
gene id: 446462:AMIR_RS35080
uniprot id: C6WSK0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446462:AMIR RS20310
gene id: 446462:AMIR_RS20310
uniprot id: C6WFZ6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

446462:AMIR RS05955
gene id: 446462:AMIR_RS05955
uniprot id: C6WR89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS26050
gene id: 446462:AMIR_RS26050
uniprot id: C6W903
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446462:AMIR RS22905
gene id: 446462:AMIR_RS22905
uniprot id: C6WLP4
names: Function
names: Similarity
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.
messages: In the C-terminal section; belongs to the NRP synthetase family.

446462:AMIR RS04335
gene id: 446462:AMIR_RS04335
uniprot id: C6WM93
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446462:AMIR RS06520
gene id: 446462:AMIR_RS06520
uniprot id: C6WRJ9
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446462:AMIR RS16500
gene id: 446462:AMIR_RS16500
uniprot id: C6W8W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the faeC family.
messages: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.
messages: Secreted

446462:AMIR RS32525
gene id: 446462:AMIR_RS32525
uniprot id: C6WLX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

446462:AMIR RS32070
gene id: 446462:AMIR_RS32070
uniprot id: C6WKM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS28435
gene id: 446462:AMIR_RS28435
uniprot id: C6WDB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS29275
gene id: 446462:AMIR_RS29275
uniprot id: C6WEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

446462:AMIR RS09895
gene id: 446462:AMIR_RS09895
uniprot id: C6WFI9
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446462:AMIR RS21100
gene id: 446462:AMIR_RS21100
uniprot id: C6WIK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

446462:AMIR RS31055
gene id: 446462:AMIR_RS31055
uniprot id: C6WIZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

446462:AMIR RS23345
gene id: 446462:AMIR_RS23345
uniprot id: C6WN12
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS32250
gene id: 446462:AMIR_RS32250
uniprot id: C6WLS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

446462:AMIR RS19430
gene id: 446462:AMIR_RS19430
uniprot id: C6WEH4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS06815
gene id: 446462:AMIR_RS06815
uniprot id: C6W9E8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

446462:AMIR RS03885
gene id: 446462:AMIR_RS03885
uniprot id: C6WKY1
names: Similarity
messages: Belongs to the LOG family.

446462:AMIR RS31835
gene id: 446462:AMIR_RS31835
uniprot id: C6WKH2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446462:AMIR RS06860
gene id: 446462:AMIR_RS06860
uniprot id: C6W9F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

446462:AMIR RS21485
gene id: 446462:AMIR_RS21485
uniprot id: C6WIS6
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

446462:AMIR RS18635
gene id: 446462:AMIR_RS18635
uniprot id: C6WD02
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS30115
gene id: 446462:AMIR_RS30115
uniprot id: C6WGB9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS13020
gene id: 446462:AMIR_RS13020
uniprot id: C6WML3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS21090
gene id: 446462:AMIR_RS21090
uniprot id: C6WIK0
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS07755
gene id: 446462:AMIR_RS07755
uniprot id: C6WAM7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446462:AMIR RS08530
gene id: 446462:AMIR_RS08530
uniprot id: C6WCN0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

446462:AMIR RS17940
gene id: 446462:AMIR_RS17940
uniprot id: C6WBS2
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS30805
gene id: 446462:AMIR_RS30805
uniprot id: C6WHS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS24885
gene id: 446462:AMIR_RS24885
uniprot id: C6WS17
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS17275
gene id: 446462:AMIR_RS17275
uniprot id: C6WAN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS11220
gene id: 446462:AMIR_RS11220
uniprot id: C6WID5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS29970
gene id: 446462:AMIR_RS29970
uniprot id: C6WG89
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

446462:AMIR RS34080
gene id: 446462:AMIR_RS34080
uniprot id: C6WQX9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446462:AMIR RS02055
gene id: 446462:AMIR_RS02055
uniprot id: C6WGQ7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

446462:AMIR RS25785
gene id: 446462:AMIR_RS25785
uniprot id: C6W8H3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

446462:AMIR RS22870
gene id: 446462:AMIR_RS22870
uniprot id: C6WLN8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

446462:AMIR RS10565
gene id: 446462:AMIR_RS10565
uniprot id: C6WGY4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

446462:AMIR RS13460
gene id: 446462:AMIR_RS13460
uniprot id: C6WNV7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS26245
gene id: 446462:AMIR_RS26245
uniprot id: C6W943
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

446462:AMIR RS30495
gene id: 446462:AMIR_RS30495
uniprot id: C6WHK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

446462:AMIR RS15370
gene id: 446462:AMIR_RS15370
uniprot id: C6W7W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS30960
gene id: 446462:AMIR_RS30960
uniprot id: C6WIX4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

446462:AMIR RS26915
gene id: 446462:AMIR_RS26915
uniprot id: C6WA61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

446462:AMIR RS32965
gene id: 446462:AMIR_RS32965
uniprot id: C6WN86
names: Similarity
messages: Belongs to the UPF0234 family.

446462:AMIR RS20360
gene id: 446462:AMIR_RS20360
uniprot id: C6WG06
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS31345
gene id: 446462:AMIR_RS31345
uniprot id: C6WJ49
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS07555
gene id: 446462:AMIR_RS07555
uniprot id: C6WAJ0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446462:AMIR RS06000
gene id: 446462:AMIR_RS06000
uniprot id: C6WR98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

446462:AMIR RS07965
gene id: 446462:AMIR_RS07965
uniprot id: C6WBG7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS31740
gene id: 446462:AMIR_RS31740
uniprot id: C6WKF4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

446462:AMIR RS06165
gene id: 446462:AMIR_RS06165
uniprot id: C6WRD0
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

446462:AMIR RS22370
gene id: 446462:AMIR_RS22370
uniprot id: C6WLE5
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS03255
gene id: 446462:AMIR_RS03255
uniprot id: C6WJI0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

446462:AMIR RS16170
gene id: 446462:AMIR_RS16170
uniprot id: C6W8P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

446462:AMIR RS26175
gene id: 446462:AMIR_RS26175
uniprot id: C6W929
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446462:AMIR RS29445
gene id: 446462:AMIR_RS29445
uniprot id: C6WEX5
names: Similarity
messages: Belongs to the malate synthase family.

446462:AMIR RS11475
gene id: 446462:AMIR_RS11475
uniprot id: C6WII5
names: Similarity
messages: Belongs to the AHA1 family.

446462:AMIR RS23080
gene id: 446462:AMIR_RS23080
uniprot id: C6WMV8
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS30470
gene id: 446462:AMIR_RS30470
uniprot id: C6WHK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

446462:AMIR RS11035
gene id: 446462:AMIR_RS11035
uniprot id: C6WIA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

446462:AMIR RS13400
gene id: 446462:AMIR_RS13400
uniprot id: C6WNU6
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32820
gene id: 446462:AMIR_RS32820
uniprot id: C6WN60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446462:AMIR RS29470
gene id: 446462:AMIR_RS29470
uniprot id: C6WEY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446462:AMIR RS27355
gene id: 446462:AMIR_RS27355
uniprot id: C6WB47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

446462:AMIR RS10425
gene id: 446462:AMIR_RS10425
uniprot id: C6WGV6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446462:AMIR RS29015
gene id: 446462:AMIR_RS29015
uniprot id: C6WDM9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446462:AMIR RS20145
gene id: 446462:AMIR_RS20145
uniprot id: C6WFW8
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

446462:AMIR RS13870
gene id: 446462:AMIR_RS13870
uniprot id: C6WP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

446462:AMIR RS18245
gene id: 446462:AMIR_RS18245
uniprot id: C6WBX9
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS11270
gene id: 446462:AMIR_RS11270
uniprot id: C6WIE5
names: Similarity
messages: Belongs to the AHA1 family.

446462:AMIR RS08545
gene id: 446462:AMIR_RS08545
uniprot id: C6WCN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS10660
gene id: 446462:AMIR_RS10660
uniprot id: C6WH02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

446462:AMIR RS08025
gene id: 446462:AMIR_RS08025
uniprot id: C6WBH9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS14130
gene id: 446462:AMIR_RS14130
uniprot id: C6WQA1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446462:AMIR RS16750
gene id: 446462:AMIR_RS16750
uniprot id: C6W9N7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

446462:AMIR RS33920
gene id: 446462:AMIR_RS33920
uniprot id: C6WPU1
names: Similarity
messages: Belongs to the TPP enzyme family.

446462:AMIR RS33815
gene id: 446462:AMIR_RS33815
uniprot id: C6WPR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

446462:AMIR RS34390
gene id: 446462:AMIR_RS34390
uniprot id: C6WR43
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS05070
gene id: 446462:AMIR_RS05070
uniprot id: C6WNP8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

446462:AMIR RS04265
gene id: 446462:AMIR_RS04265
uniprot id: C6WM79
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446462:AMIR RS10160
gene id: 446462:AMIR_RS10160
uniprot id: C6WFN7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS15480
gene id: 446462:AMIR_RS15480
uniprot id: C6W7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446462:AMIR RS02475
gene id: 446462:AMIR_RS02475
uniprot id: C6WI07
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS18475
gene id: 446462:AMIR_RS18475
uniprot id: C6WC23
names: Similarity
messages: Belongs to the YciI family.

446462:AMIR RS32530
gene id: 446462:AMIR_RS32530
uniprot id: C6WLY0
names: Similarity
messages: Belongs to the WXG100 family.

446462:AMIR RS26000
gene id: 446462:AMIR_RS26000
uniprot id: C6W8Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

446462:AMIR RS04380
gene id: 446462:AMIR_RS04380
uniprot id: C6WMA2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

446462:AMIR RS25155
gene id: 446462:AMIR_RS25155
uniprot id: C6WS74
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446462:AMIR RS05820
gene id: 446462:AMIR_RS05820
uniprot id: C6WQ57
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS26840
gene id: 446462:AMIR_RS26840
uniprot id: C6WA46
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

446462:AMIR RS16390
gene id: 446462:AMIR_RS16390
uniprot id: C6W8T8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS12245
gene id: 446462:AMIR_RS12245
uniprot id: C6WL33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS17280
gene id: 446462:AMIR_RS17280
uniprot id: C6WAP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS03250
gene id: 446462:AMIR_RS03250
uniprot id: C6WJH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

446462:AMIR RS32770
gene id: 446462:AMIR_RS32770
uniprot id: C6WM29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

446462:AMIR RS03870
gene id: 446462:AMIR_RS03870
uniprot id: C6WKX8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS30100
gene id: 446462:AMIR_RS30100
uniprot id: C6WGB6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

446462:AMIR RS13855
gene id: 446462:AMIR_RS13855
uniprot id: C6WP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446462:AMIR RS21085
gene id: 446462:AMIR_RS21085
uniprot id: C6WIJ9
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

446462:AMIR RS26965
gene id: 446462:AMIR_RS26965
uniprot id: C6WA71
names: Similarity
messages: Belongs to the TlyA family.

446462:AMIR RS34905
gene id: 446462:AMIR_RS34905
uniprot id: C6WSG6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS28845
gene id: 446462:AMIR_RS28845
uniprot id: C6WDJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

446462:AMIR RS29990
gene id: 446462:AMIR_RS29990
uniprot id: C6WG93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

446462:AMIR RS28350
gene id: 446462:AMIR_RS28350
uniprot id: C6WCE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

446462:AMIR RS15745
gene id: 446462:AMIR_RS15745
uniprot id: C6W841
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS09010
gene id: 446462:AMIR_RS09010
uniprot id: C6WCX7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

446462:AMIR RS32750
gene id: 446462:AMIR_RS32750
uniprot id: C6WM25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

446462:AMIR RS04910
gene id: 446462:AMIR_RS04910
uniprot id: C6WNL6
names: Similarity
messages: Belongs to the terpene synthase family.

446462:AMIR RS32095
gene id: 446462:AMIR_RS32095
uniprot id: C6WKM5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

446462:AMIR RS05390
gene id: 446462:AMIR_RS05390
uniprot id: C6WPX4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

446462:AMIR RS32670
gene id: 446462:AMIR_RS32670
uniprot id: C6WM09
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

446462:AMIR RS23725
gene id: 446462:AMIR_RS23725
uniprot id: C6WP99
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

446462:AMIR RS23300
gene id: 446462:AMIR_RS23300
uniprot id: C6WN02
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446462:AMIR RS12880
gene id: 446462:AMIR_RS12880
uniprot id: C6WMI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

446462:AMIR RS05655
gene id: 446462:AMIR_RS05655
uniprot id: C6WQ26
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

446462:AMIR RS18575
gene id: 446462:AMIR_RS18575
uniprot id: C6WCZ0
names: Similarity
messages: Belongs to the LuxC family.

446462:AMIR RS05230
gene id: 446462:AMIR_RS05230
uniprot id: C6WNS9
names: Subcellular Location Annotation
messages: Cytoplasm

446462:AMIR RS19555
gene id: 446462:AMIR_RS19555
uniprot id: C6WEJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446462:AMIR RS24910
gene id: 446462:AMIR_RS24910
uniprot id: C6WS22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

446462:AMIR RS19510
gene id: 446462:AMIR_RS19510
uniprot id: C6WEI8
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS00355
gene id: 446462:AMIR_RS00355
uniprot id: C6WDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446462:AMIR RS33060
gene id: 446462:AMIR_RS33060
uniprot id: C6WNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446462:AMIR RS21825
gene id: 446462:AMIR_RS21825
uniprot id: C6WK20
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS11705
gene id: 446462:AMIR_RS11705
uniprot id: C6WJQ1
names: Similarity
messages: Belongs to the MotB family.

446462:AMIR RS29915
gene id: 446462:AMIR_RS29915
uniprot id: C6WG78
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

446462:AMIR RS05945
gene id: 446462:AMIR_RS05945
uniprot id: C6WR87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

446462:AMIR RS07520
gene id: 446462:AMIR_RS07520
uniprot id: C6WAI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

446462:AMIR RS42145
gene id: 446462:AMIR_RS42145
uniprot id: C6WJZ9
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

446462:AMIR RS15220
gene id: 446462:AMIR_RS15220
uniprot id: C6WRX0
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS25815
gene id: 446462:AMIR_RS25815
uniprot id: C6W8I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

446462:AMIR RS17150
gene id: 446462:AMIR_RS17150
uniprot id: C6W9W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446462:AMIR RS28675
gene id: 446462:AMIR_RS28675
uniprot id: C6WDG3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS05270
gene id: 446462:AMIR_RS05270
uniprot id: C6WNT7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

446462:AMIR RS28775
gene id: 446462:AMIR_RS28775
uniprot id: C6WDI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

446462:AMIR RS32970
gene id: 446462:AMIR_RS32970
uniprot id: C6WN87
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

446462:AMIR RS01925
gene id: 446462:AMIR_RS01925
uniprot id: C6WGN1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS30605
gene id: 446462:AMIR_RS30605
uniprot id: C6WHN0
names: Similarity
messages: Belongs to the AHA1 family.

446462:AMIR RS29360
gene id: 446462:AMIR_RS29360
uniprot id: C6WEV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

446462:AMIR RS02075
gene id: 446462:AMIR_RS02075
uniprot id: C6WGR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

446462:AMIR RS26635
gene id: 446462:AMIR_RS26635
uniprot id: C6WA04
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

446462:AMIR RS11325
gene id: 446462:AMIR_RS11325
uniprot id: C6WIF5
names: Similarity
messages: Belongs to the peptidase M24B family.

446462:AMIR RS29860
gene id: 446462:AMIR_RS29860
uniprot id: C6WG67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS25870
gene id: 446462:AMIR_RS25870
uniprot id: C6W8J1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

446462:AMIR RS03520
gene id: 446462:AMIR_RS03520
uniprot id: C6WKQ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446462:AMIR RS00170
gene id: 446462:AMIR_RS00170
uniprot id: C6WCI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

446462:AMIR RS29315
gene id: 446462:AMIR_RS29315
uniprot id: C6WEU9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

446462:AMIR RS11235
gene id: 446462:AMIR_RS11235
uniprot id: C6WID8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

446462:AMIR RS12105
gene id: 446462:AMIR_RS12105
uniprot id: C6WJY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

446462:AMIR RS29120
gene id: 446462:AMIR_RS29120
uniprot id: C6WER1
names: Similarity
messages: Belongs to the UPF0098 family.

446462:AMIR RS10990
gene id: 446462:AMIR_RS10990
uniprot id: C6WI93
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

446462:AMIR RS26315
gene id: 446462:AMIR_RS26315
uniprot id: C6W957
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS03035
gene id: 446462:AMIR_RS03035
uniprot id: C6WJD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

446462:AMIR RS22475
gene id: 446462:AMIR_RS22475
uniprot id: C6WLG6
names: Similarity
messages: Belongs to the peptidase S1 family.

446462:AMIR RS15965
gene id: 446462:AMIR_RS15965
uniprot id: C6W8K7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS26045
gene id: 446462:AMIR_RS26045
uniprot id: C6W902
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

446462:AMIR RS23135
gene id: 446462:AMIR_RS23135
uniprot id: C6WMW8
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32725
gene id: 446462:AMIR_RS32725
uniprot id: C6WM20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

446462:AMIR RS26775
gene id: 446462:AMIR_RS26775
uniprot id: C6WA33
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS25260
gene id: 446462:AMIR_RS25260
uniprot id: C6WS97
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS24525
gene id: 446462:AMIR_RS24525
uniprot id: C6WQS4
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06800
gene id: 446462:AMIR_RS06800
uniprot id: C6W9E5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS01950
gene id: 446462:AMIR_RS01950
uniprot id: C6WGN6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446462:AMIR RS10550
gene id: 446462:AMIR_RS10550
uniprot id: C6WGY1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS28595
gene id: 446462:AMIR_RS28595
uniprot id: C6WDE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

446462:AMIR RS11540
gene id: 446462:AMIR_RS11540
uniprot id: C6WJL7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS07095
gene id: 446462:AMIR_RS07095
uniprot id: C6W9K4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

446462:AMIR RS11355
gene id: 446462:AMIR_RS11355
uniprot id: C6WIG1
names: Similarity
messages: Belongs to the peptidase S58 family.

446462:AMIR RS21360
gene id: 446462:AMIR_RS21360
uniprot id: C6WIQ2
names: Similarity
messages: Belongs to the EfeM/EfeO family.

446462:AMIR RS19665
gene id: 446462:AMIR_RS19665
uniprot id: C6WEL5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS31130
gene id: 446462:AMIR_RS31130
uniprot id: C6WJ08
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

446462:AMIR RS13290
gene id: 446462:AMIR_RS13290
uniprot id: C6WMR6
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

446462:AMIR RS34615
gene id: 446462:AMIR_RS34615
uniprot id: C6WSA9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

446462:AMIR RS14435
gene id: 446462:AMIR_RS14435
uniprot id: C6WQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS11700
gene id: 446462:AMIR_RS11700
uniprot id: C6WJQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

446462:AMIR RS13060
gene id: 446462:AMIR_RS13060
uniprot id: C6WMM1
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS18950
gene id: 446462:AMIR_RS18950
uniprot id: C6WD61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

446462:AMIR RS29140
gene id: 446462:AMIR_RS29140
uniprot id: C6WER5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS10140
gene id: 446462:AMIR_RS10140
uniprot id: C6WFN3
names: Similarity
messages: Belongs to the amidinotransferase family.

446462:AMIR RS33065
gene id: 446462:AMIR_RS33065
uniprot id: C6WNA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446462:AMIR RS11775
gene id: 446462:AMIR_RS11775
uniprot id: C6WJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

446462:AMIR RS06640
gene id: 446462:AMIR_RS06640
uniprot id: C6W9B3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

446462:AMIR RS29215
gene id: 446462:AMIR_RS29215
uniprot id: C6WET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS27090
gene id: 446462:AMIR_RS27090
uniprot id: C6WA94
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

446462:AMIR RS28920
gene id: 446462:AMIR_RS28920
uniprot id: C6WDL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

446462:AMIR RS01630
gene id: 446462:AMIR_RS01630
uniprot id: C6WGH3
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

446462:AMIR RS04715
gene id: 446462:AMIR_RS04715
uniprot id: C6WNI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

446462:AMIR RS25065
gene id: 446462:AMIR_RS25065
uniprot id: C6WS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS21475
gene id: 446462:AMIR_RS21475
uniprot id: C6WIS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS25950
gene id: 446462:AMIR_RS25950
uniprot id: C6W8Y3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS06355
gene id: 446462:AMIR_RS06355
uniprot id: C6WRG8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

446462:AMIR RS25245
gene id: 446462:AMIR_RS25245
uniprot id: C6WS94
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS19225
gene id: 446462:AMIR_RS19225
uniprot id: C6WED5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS09230
gene id: 446462:AMIR_RS09230
uniprot id: C6WE45
names: Similarity
messages: Belongs to the alkaline phosphatase family.

446462:AMIR RS01285
gene id: 446462:AMIR_RS01285
uniprot id: C6WF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

446462:AMIR RS19240
gene id: 446462:AMIR_RS19240
uniprot id: C6WED8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446462:AMIR RS03295
gene id: 446462:AMIR_RS03295
uniprot id: C6WJI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

446462:AMIR RS25730
gene id: 446462:AMIR_RS25730
uniprot id: C6W8G2
names: Similarity
messages: Belongs to the GPI family.

446462:AMIR RS04935
gene id: 446462:AMIR_RS04935
uniprot id: C6WNM2
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

446462:AMIR RS08105
gene id: 446462:AMIR_RS08105
uniprot id: C6WBJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

446462:AMIR RS29545
gene id: 446462:AMIR_RS29545
uniprot id: C6WEZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

446462:AMIR RS32870
gene id: 446462:AMIR_RS32870
uniprot id: C6WN70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

446462:AMIR RS29530
gene id: 446462:AMIR_RS29530
uniprot id: C6WEZ2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

446462:AMIR RS23670
gene id: 446462:AMIR_RS23670
uniprot id: C6WP88
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

446462:AMIR RS11670
gene id: 446462:AMIR_RS11670
uniprot id: C6WJP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

446462:AMIR RS01860
gene id: 446462:AMIR_RS01860
uniprot id: C6WGL9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

446462:AMIR RS07355
gene id: 446462:AMIR_RS07355
uniprot id: C6WAF2
names: Similarity
messages: Belongs to the histone deacetylase family.

446462:AMIR RS05435
gene id: 446462:AMIR_RS05435
uniprot id: C6WPY3
names: Similarity
messages: Belongs to the CdaR family.

446462:AMIR RS29125
gene id: 446462:AMIR_RS29125
uniprot id: C6WER2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

446462:AMIR RS27095
gene id: 446462:AMIR_RS27095
uniprot id: C6WA95
names: Similarity
messages: Belongs to the heat shock protein 90 family.

446462:AMIR RS13335
gene id: 446462:AMIR_RS13335
uniprot id: C6WMS5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS11085
gene id: 446462:AMIR_RS11085
uniprot id: C6WIB0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

446462:AMIR RS33180
gene id: 446462:AMIR_RS33180
uniprot id: C6WND1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

446462:AMIR RS11690
gene id: 446462:AMIR_RS11690
uniprot id: C6WJP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

446462:AMIR RS33735
gene id: 446462:AMIR_RS33735
uniprot id: C6WPQ2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS30420
gene id: 446462:AMIR_RS30420
uniprot id: C6WHJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

446462:AMIR RS16495
gene id: 446462:AMIR_RS16495
uniprot id: C6W8V9
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446462:AMIR RS18065
gene id: 446462:AMIR_RS18065
uniprot id: C6WBU7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS06870
gene id: 446462:AMIR_RS06870
uniprot id: C6W9F9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS29460
gene id: 446462:AMIR_RS29460
uniprot id: C6WEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

446462:AMIR RS20440
gene id: 446462:AMIR_RS20440
uniprot id: C6WG22
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS14920
gene id: 446462:AMIR_RS14920
uniprot id: C6WRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS07650
gene id: 446462:AMIR_RS07650
uniprot id: C6WAK9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

446462:AMIR RS10265
gene id: 446462:AMIR_RS10265
uniprot id: C6WGS4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

446462:AMIR RS22190
gene id: 446462:AMIR_RS22190
uniprot id: C6WK89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS09320
gene id: 446462:AMIR_RS09320
uniprot id: C6WE62
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

446462:AMIR RS01640
gene id: 446462:AMIR_RS01640
uniprot id: C6WGH5
names: Subcellular Location Annotation
messages: Mitochondrion

446462:AMIR RS28060
gene id: 446462:AMIR_RS28060
uniprot id: C6WC88
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446462:AMIR RS31870
gene id: 446462:AMIR_RS31870
uniprot id: C6WKH9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

446462:AMIR RS06345
gene id: 446462:AMIR_RS06345
uniprot id: C6WRG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS02365
gene id: 446462:AMIR_RS02365
uniprot id: C6WHY5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

446462:AMIR RS23920
gene id: 446462:AMIR_RS23920
uniprot id: C6WPD8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

446462:AMIR RS03030
gene id: 446462:AMIR_RS03030
uniprot id: C6WJD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

446462:AMIR RS30490
gene id: 446462:AMIR_RS30490
uniprot id: C6WHK8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

446462:AMIR RS07395
gene id: 446462:AMIR_RS07395
uniprot id: C6WAG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS29825
gene id: 446462:AMIR_RS29825
uniprot id: C6WG60
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

446462:AMIR RS07025
gene id: 446462:AMIR_RS07025
uniprot id: C6W9J0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

446462:AMIR RS02350
gene id: 446462:AMIR_RS02350
uniprot id: C6WHY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

446462:AMIR RS33540
gene id: 446462:AMIR_RS33540
uniprot id: C6WPL6
names: Similarity
messages: Belongs to the peptidase C56 family.

446462:AMIR RS18995
gene id: 446462:AMIR_RS18995
uniprot id: C6WD70
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

446462:AMIR RS03145
gene id: 446462:AMIR_RS03145
uniprot id: C6WJF9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

446462:AMIR RS07330
gene id: 446462:AMIR_RS07330
uniprot id: C6WAE7
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

446462:AMIR RS00070
gene id: 446462:AMIR_RS00070
uniprot id: C6WCG6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

446462:AMIR RS28275
gene id: 446462:AMIR_RS28275
uniprot id: C6WCD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

446462:AMIR RS00385
gene id: 446462:AMIR_RS00385
uniprot id: C6WDQ6
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS31195
gene id: 446462:AMIR_RS31195
uniprot id: C6WJ20
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS32380
gene id: 446462:AMIR_RS32380
uniprot id: C6WLV0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

446462:AMIR RS00715
gene id: 446462:AMIR_RS00715
uniprot id: C6WDW7
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

446462:AMIR RS23715
gene id: 446462:AMIR_RS23715
uniprot id: C6WP97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS14780
gene id: 446462:AMIR_RS14780
uniprot id: C6WRN6
names: Similarity
messages: Belongs to the universal stress protein A family.

446462:AMIR RS28470
gene id: 446462:AMIR_RS28470
uniprot id: C6WDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS29040
gene id: 446462:AMIR_RS29040
uniprot id: C6WEP5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

446462:AMIR RS29630
gene id: 446462:AMIR_RS29630
uniprot id: C6WF11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

446462:AMIR RS13470
gene id: 446462:AMIR_RS13470
uniprot id: C6WNV9
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS28380
gene id: 446462:AMIR_RS28380
uniprot id: C6WCF3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

446462:AMIR RS11810
gene id: 446462:AMIR_RS11810
uniprot id: C6WJS2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

446462:AMIR RS28760
gene id: 446462:AMIR_RS28760
uniprot id: C6WDI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

446462:AMIR RS31260
gene id: 446462:AMIR_RS31260
uniprot id: C6WJ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

446462:AMIR RS06210
gene id: 446462:AMIR_RS06210
uniprot id: C6WRD9
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

446462:AMIR RS14465
gene id: 446462:AMIR_RS14465
uniprot id: C6WQG7
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS26060
gene id: 446462:AMIR_RS26060
uniprot id: C6W905
names: Similarity
messages: Belongs to the peptidase A24 family.

446462:AMIR RS05465
gene id: 446462:AMIR_RS05465
uniprot id: C6WPY9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446462:AMIR RS28390
gene id: 446462:AMIR_RS28390
uniprot id: C6WDA6
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

446462:AMIR RS24285
gene id: 446462:AMIR_RS24285
uniprot id: C6WQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS00010
gene id: 446462:AMIR_RS00010
uniprot id: C6WCF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

446462:AMIR RS01320
gene id: 446462:AMIR_RS01320
uniprot id: C6WF95
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS10525
gene id: 446462:AMIR_RS10525
uniprot id: C6WGX6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

446462:AMIR RS05495
gene id: 446462:AMIR_RS05495
uniprot id: C6WPZ5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

446462:AMIR RS04545
gene id: 446462:AMIR_RS04545
uniprot id: C6WMD5
names: Similarity
messages: Belongs to the glutamine synthetase family.

446462:AMIR RS15810
gene id: 446462:AMIR_RS15810
uniprot id: C6W854
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS19060
gene id: 446462:AMIR_RS19060
uniprot id: C6WD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

446462:AMIR RS32580
gene id: 446462:AMIR_RS32580
uniprot id: C6WLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

446462:AMIR RS08515
gene id: 446462:AMIR_RS08515
uniprot id: C6WCM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446462:AMIR RS27315
gene id: 446462:AMIR_RS27315
uniprot id: C6WB39
names: Similarity
messages: Belongs to the peptidase S9C family.

446462:AMIR RS14455
gene id: 446462:AMIR_RS14455
uniprot id: C6WQG5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446462:AMIR RS07340
gene id: 446462:AMIR_RS07340
uniprot id: C6WAE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS23485
gene id: 446462:AMIR_RS23485
uniprot id: C6WN40
names: Similarity
messages: Belongs to the DapA family.

446462:AMIR RS02480
gene id: 446462:AMIR_RS02480
uniprot id: C6WI08
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

446462:AMIR RS11725
gene id: 446462:AMIR_RS11725
uniprot id: C6WJQ5
names: Similarity
messages: Belongs to the FlgD family.

446462:AMIR RS31235
gene id: 446462:AMIR_RS31235
uniprot id: C6WJ28
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

446462:AMIR RS02145
gene id: 446462:AMIR_RS02145
uniprot id: C6WHU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

446462:AMIR RS32780
gene id: 446462:AMIR_RS32780
uniprot id: C6WN52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

446462:AMIR RS03800
gene id: 446462:AMIR_RS03800
uniprot id: C6WKW3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

446462:AMIR RS16985
gene id: 446462:AMIR_RS16985
uniprot id: C6W9T4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS01885
gene id: 446462:AMIR_RS01885
uniprot id: C6WGM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

446462:AMIR RS13920
gene id: 446462:AMIR_RS13920
uniprot id: C6WP46
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS29430
gene id: 446462:AMIR_RS29430
uniprot id: C6WEX2
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

446462:AMIR RS27445
gene id: 446462:AMIR_RS27445
uniprot id: C6WB65
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS15995
gene id: 446462:AMIR_RS15995
uniprot id: C6W8L2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS01510
gene id: 446462:AMIR_RS01510
uniprot id: C6WGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS30860
gene id: 446462:AMIR_RS30860
uniprot id: C6WHT1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS28970
gene id: 446462:AMIR_RS28970
uniprot id: C6WDM0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS22875
gene id: 446462:AMIR_RS22875
uniprot id: C6WLN9
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS11755
gene id: 446462:AMIR_RS11755
uniprot id: C6WJR1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

446462:AMIR RS28360
gene id: 446462:AMIR_RS28360
uniprot id: C6WCE9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS18990
gene id: 446462:AMIR_RS18990
uniprot id: C6WD69
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

446462:AMIR RS03825
gene id: 446462:AMIR_RS03825
uniprot id: C6WKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS18530
gene id: 446462:AMIR_RS18530
uniprot id: C6WCY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

446462:AMIR RS11315
gene id: 446462:AMIR_RS11315
uniprot id: C6WIF3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

446462:AMIR RS23780
gene id: 446462:AMIR_RS23780
uniprot id: C6WPB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS33115
gene id: 446462:AMIR_RS33115
uniprot id: C6WNB7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

446462:AMIR RS30510
gene id: 446462:AMIR_RS30510
uniprot id: C6WHL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

446462:AMIR RS17310
gene id: 446462:AMIR_RS17310
uniprot id: C6WAP6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446462:AMIR RS06050
gene id: 446462:AMIR_RS06050
uniprot id: C6WRA7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

446462:AMIR RS09325
gene id: 446462:AMIR_RS09325
uniprot id: C6WE63
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446462:AMIR RS06955
gene id: 446462:AMIR_RS06955
uniprot id: C6W9H6
names: Similarity
messages: Belongs to the arsA ATPase family.

446462:AMIR RS04070
gene id: 446462:AMIR_RS04070
uniprot id: C6WM38
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS10015
gene id: 446462:AMIR_RS10015
uniprot id: C6WFL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sugar phosphate cyclases superfamily. EVS family.
messages: Binds 1 divalent metal cation per subunit. Co(2+) is the preferred cofactor.
messages: Catalyzes the conversion of sedoheptulose 7-phosphate to 2-epi-valiolone, which may serve as an alternative precursor for aminocyclitol biosynthesis.

446462:AMIR RS13910
gene id: 446462:AMIR_RS13910
uniprot id: C6WP44
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32775
gene id: 446462:AMIR_RS32775
uniprot id: C6WM30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

446462:AMIR RS32325
gene id: 446462:AMIR_RS32325
uniprot id: C6WLT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

446462:AMIR RS30095
gene id: 446462:AMIR_RS30095
uniprot id: C6WGB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

446462:AMIR RS01215
gene id: 446462:AMIR_RS01215
uniprot id: C6WF73
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446462:AMIR RS00410
gene id: 446462:AMIR_RS00410
uniprot id: C6WDR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

446462:AMIR RS03945
gene id: 446462:AMIR_RS03945
uniprot id: C6WKZ3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

446462:AMIR RS34570
gene id: 446462:AMIR_RS34570
uniprot id: C6WR77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS30370
gene id: 446462:AMIR_RS30370
uniprot id: C6WHI5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

446462:AMIR RS10605
gene id: 446462:AMIR_RS10605
uniprot id: C6WGZ2
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS29055
gene id: 446462:AMIR_RS29055
uniprot id: C6WEP8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS10655
gene id: 446462:AMIR_RS10655
uniprot id: C6WH01
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

446462:AMIR RS29560
gene id: 446462:AMIR_RS29560
uniprot id: C6WEZ8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

446462:AMIR RS34865
gene id: 446462:AMIR_RS34865
uniprot id: C6WSF9
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

446462:AMIR RS32280
gene id: 446462:AMIR_RS32280
uniprot id: C6WLT0
names: Similarity
messages: Belongs to the histone deacetylase family.

446462:AMIR RS04750
gene id: 446462:AMIR_RS04750
uniprot id: C6WNI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

446462:AMIR RS15135
gene id: 446462:AMIR_RS15135
uniprot id: C6WRV4
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

446462:AMIR RS34085
gene id: 446462:AMIR_RS34085
uniprot id: C6WQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446462:AMIR RS32610
gene id: 446462:AMIR_RS32610
uniprot id: C6WLZ6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

446462:AMIR RS08440
gene id: 446462:AMIR_RS08440
uniprot id: C6WCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS24155
gene id: 446462:AMIR_RS24155
uniprot id: C6WQJ7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

446462:AMIR RS29755
gene id: 446462:AMIR_RS29755
uniprot id: C6WG48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

446462:AMIR RS09395
gene id: 446462:AMIR_RS09395
uniprot id: C6WE77
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

446462:AMIR RS05930
gene id: 446462:AMIR_RS05930
uniprot id: C6WR84
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS05920
gene id: 446462:AMIR_RS05920
uniprot id: C6WQ77
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS19860
gene id: 446462:AMIR_RS19860
uniprot id: C6WFR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

446462:AMIR RS00205
gene id: 446462:AMIR_RS00205
uniprot id: C6WCJ3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS25170
gene id: 446462:AMIR_RS25170
uniprot id: C6WS77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS26005
gene id: 446462:AMIR_RS26005
uniprot id: C6W8Z4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

446462:AMIR RS30530
gene id: 446462:AMIR_RS30530
uniprot id: C6WHL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS09075
gene id: 446462:AMIR_RS09075
uniprot id: C6WE14
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

446462:AMIR RS32885
gene id: 446462:AMIR_RS32885
uniprot id: C6WN73
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

446462:AMIR RS28260
gene id: 446462:AMIR_RS28260
uniprot id: C6WCC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

446462:AMIR RS03325
gene id: 446462:AMIR_RS03325
uniprot id: C6WJJ1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS30690
gene id: 446462:AMIR_RS30690
uniprot id: C6WHP8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446462:AMIR RS05790
gene id: 446462:AMIR_RS05790
uniprot id: C6WQ51
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

446462:AMIR RS03230
gene id: 446462:AMIR_RS03230
uniprot id: C6WJH5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

446462:AMIR RS05965
gene id: 446462:AMIR_RS05965
uniprot id: C6WR91
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS16975
gene id: 446462:AMIR_RS16975
uniprot id: C6W9T2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS28420
gene id: 446462:AMIR_RS28420
uniprot id: C6WDB2
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

446462:AMIR RS01555
gene id: 446462:AMIR_RS01555
uniprot id: C6WGF9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS33325
gene id: 446462:AMIR_RS33325
uniprot id: C6WNG0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

446462:AMIR RS32230
gene id: 446462:AMIR_RS32230
uniprot id: C6WLR9
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS15790
gene id: 446462:AMIR_RS15790
uniprot id: C6W850
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

446462:AMIR RS31465
gene id: 446462:AMIR_RS31465
uniprot id: C6WJ73
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

446462:AMIR RS12465
gene id: 446462:AMIR_RS12465
uniprot id: C6WL76
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS15380
gene id: 446462:AMIR_RS15380
uniprot id: C6W7X1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS02210
gene id: 446462:AMIR_RS02210
uniprot id: C6WHV4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

446462:AMIR RS29505
gene id: 446462:AMIR_RS29505
uniprot id: C6WEY7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS21840
gene id: 446462:AMIR_RS21840
uniprot id: C6WK23
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS25030
gene id: 446462:AMIR_RS25030
uniprot id: C6WS49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS06380
gene id: 446462:AMIR_RS06380
uniprot id: C6WRH3
names: Similarity
messages: Belongs to the peptidase S51 family.

446462:AMIR RS07570
gene id: 446462:AMIR_RS07570
uniprot id: C6WAJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

446462:AMIR RS02775
gene id: 446462:AMIR_RS02775
uniprot id: C6WI66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS01610
gene id: 446462:AMIR_RS01610
uniprot id: C6WGG9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

446462:AMIR RS26105
gene id: 446462:AMIR_RS26105
uniprot id: C6W914
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

446462:AMIR RS22340
gene id: 446462:AMIR_RS22340
uniprot id: C6WLD9
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

446462:AMIR RS25965
gene id: 446462:AMIR_RS25965
uniprot id: C6W8Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

446462:AMIR RS11790
gene id: 446462:AMIR_RS11790
uniprot id: C6WJR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

446462:AMIR RS30620
gene id: 446462:AMIR_RS30620
uniprot id: C6WHN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

446462:AMIR RS29245
gene id: 446462:AMIR_RS29245
uniprot id: C6WET6
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

446462:AMIR RS06130
gene id: 446462:AMIR_RS06130
uniprot id: C6WRC3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06895
gene id: 446462:AMIR_RS06895
uniprot id: C6W9G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

446462:AMIR RS32710
gene id: 446462:AMIR_RS32710
uniprot id: C6WM17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

446462:AMIR RS07335
gene id: 446462:AMIR_RS07335
uniprot id: C6WAE8
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

446462:AMIR RS06135
gene id: 446462:AMIR_RS06135
uniprot id: C6WRC4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

446462:AMIR RS35030
gene id: 446462:AMIR_RS35030
uniprot id: C6WSJ1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

446462:AMIR RS17660
gene id: 446462:AMIR_RS17660
uniprot id: C6WAW4
names: Subunit
messages: Monomer.

446462:AMIR RS29350
gene id: 446462:AMIR_RS29350
uniprot id: C6WEV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

446462:AMIR RS04190
gene id: 446462:AMIR_RS04190
uniprot id: C6WM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

446462:AMIR RS00590
gene id: 446462:AMIR_RS00590
uniprot id: C6WDU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

446462:AMIR RS07265
gene id: 446462:AMIR_RS07265
uniprot id: C6WAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS03245
gene id: 446462:AMIR_RS03245
uniprot id: C6WJH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS32665
gene id: 446462:AMIR_RS32665
uniprot id: C6WM08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

446462:AMIR RS28170
gene id: 446462:AMIR_RS28170
uniprot id: C6WCB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

446462:AMIR RS29840
gene id: 446462:AMIR_RS29840
uniprot id: C6WG63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

446462:AMIR RS11370
gene id: 446462:AMIR_RS11370
uniprot id: C6WIG4
names: Similarity
messages: Belongs to the DEAD box helicase family.

446462:AMIR RS31770
gene id: 446462:AMIR_RS31770
uniprot id: C6WKF9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS25205
gene id: 446462:AMIR_RS25205
uniprot id: C6WS86
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

446462:AMIR RS29365
gene id: 446462:AMIR_RS29365
uniprot id: C6WEV9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

446462:AMIR RS04520
gene id: 446462:AMIR_RS04520
uniprot id: C6WMD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

446462:AMIR RS27125
gene id: 446462:AMIR_RS27125
uniprot id: C6WAA1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

446462:AMIR RS21380
gene id: 446462:AMIR_RS21380
uniprot id: C6WIQ6
names: Similarity
messages: Belongs to the peptidase S33 family.

446462:AMIR RS35050
gene id: 446462:AMIR_RS35050
uniprot id: C6WSJ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS25145
gene id: 446462:AMIR_RS25145
uniprot id: C6WS72
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

446462:AMIR RS26920
gene id: 446462:AMIR_RS26920
uniprot id: C6WA62
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32435
gene id: 446462:AMIR_RS32435
uniprot id: C6WLW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

446462:AMIR RS34495
gene id: 446462:AMIR_RS34495
uniprot id: C6WR63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446462:AMIR RS10940
gene id: 446462:AMIR_RS10940
uniprot id: C6WI83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

446462:AMIR RS11955
gene id: 446462:AMIR_RS11955
uniprot id: C6WJV1
names: Similarity
messages: Belongs to the peptidase M7 family.

446462:AMIR RS30760
gene id: 446462:AMIR_RS30760
uniprot id: C6WHR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

446462:AMIR RS05755
gene id: 446462:AMIR_RS05755
uniprot id: C6WQ46
names: Similarity
messages: Belongs to the FPG family.

446462:AMIR RS10890
gene id: 446462:AMIR_RS10890
uniprot id: C6WI73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS14770
gene id: 446462:AMIR_RS14770
uniprot id: C6WRN3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446462:AMIR RS11125
gene id: 446462:AMIR_RS11125
uniprot id: C6WIB8
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS00600
gene id: 446462:AMIR_RS00600
uniprot id: C6WDU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

446462:AMIR RS22975
gene id: 446462:AMIR_RS22975
uniprot id: C6WMT8
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS35700
gene id: 446462:AMIR_RS35700
uniprot id: C6WQI9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

446462:AMIR RS00680
gene id: 446462:AMIR_RS00680
uniprot id: C6WDW0
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS15290
gene id: 446462:AMIR_RS15290
uniprot id: C6WRY3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS20010
gene id: 446462:AMIR_RS20010
uniprot id: C6WFU3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446462:AMIR RS09615
gene id: 446462:AMIR_RS09615
uniprot id: C6WFD2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

446462:AMIR RS08455
gene id: 446462:AMIR_RS08455
uniprot id: C6WCL5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

446462:AMIR RS32485
gene id: 446462:AMIR_RS32485
uniprot id: C6WLX1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS09285
gene id: 446462:AMIR_RS09285
uniprot id: C6WE55
names: Similarity
messages: Belongs to the peptidase S1 family.

446462:AMIR RS09045
gene id: 446462:AMIR_RS09045
uniprot id: C6WE08
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS42030
gene id: 446462:AMIR_RS42030
uniprot id: C6WEL1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446462:AMIR RS28615
gene id: 446462:AMIR_RS28615
uniprot id: C6WDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

446462:AMIR RS01665
gene id: 446462:AMIR_RS01665
uniprot id: C6WGI0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS28900
gene id: 446462:AMIR_RS28900
uniprot id: C6WDK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

446462:AMIR RS03595
gene id: 446462:AMIR_RS03595
uniprot id: C6WKS2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS32655
gene id: 446462:AMIR_RS32655
uniprot id: C6WM06
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446462:AMIR RS02230
gene id: 446462:AMIR_RS02230
uniprot id: C6WHV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

446462:AMIR RS24670
gene id: 446462:AMIR_RS24670
uniprot id: C6WQV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 62 family.
messages: Involved in the degradation of xylan and is a key enzyme in the complete degradation of the plant cell wall. It has a specific arabinofuranose-debranching activity on xylan from gramineae. Acts synergistically with the xylanases and binds specifically to xylan. From small arabinoxylo-oligosides (ranging from arabinoxylotriose to arabinoxylohexaose), it liberates arabinose and, after prolonged incubation, the purified enzyme exhibits some xylanolytic activity as well.
messages: Secreted

446462:AMIR RS06225
gene id: 446462:AMIR_RS06225
uniprot id: C6WRE2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

446462:AMIR RS06310
gene id: 446462:AMIR_RS06310
uniprot id: C6WRF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS33100
gene id: 446462:AMIR_RS33100
uniprot id: C6WNB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446462:AMIR RS06215
gene id: 446462:AMIR_RS06215
uniprot id: C6WRE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

446462:AMIR RS02200
gene id: 446462:AMIR_RS02200
uniprot id: C6WHV2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

446462:AMIR RS05880
gene id: 446462:AMIR_RS05880
uniprot id: C6WQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

446462:AMIR RS15895
gene id: 446462:AMIR_RS15895
uniprot id: C6W871
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

446462:AMIR RS09535
gene id: 446462:AMIR_RS09535
uniprot id: C6WEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

446462:AMIR RS30355
gene id: 446462:AMIR_RS30355
uniprot id: C6WHI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

446462:AMIR RS09190
gene id: 446462:AMIR_RS09190
uniprot id: C6WE37
names: Similarity
messages: Belongs to the YciI family.

446462:AMIR RS32315
gene id: 446462:AMIR_RS32315
uniprot id: C6WLT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS20035
gene id: 446462:AMIR_RS20035
uniprot id: C6WFU8
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

446462:AMIR RS05530
gene id: 446462:AMIR_RS05530
uniprot id: C6WQ03
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446462:AMIR RS32065
gene id: 446462:AMIR_RS32065
uniprot id: C6WKL9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS04290
gene id: 446462:AMIR_RS04290
uniprot id: C6WM84
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS34190
gene id: 446462:AMIR_RS34190
uniprot id: C6WR01
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS11185
gene id: 446462:AMIR_RS11185
uniprot id: C6WIC8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

446462:AMIR RS07495
gene id: 446462:AMIR_RS07495
uniprot id: C6WAH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS28225
gene id: 446462:AMIR_RS28225
uniprot id: C6WCC1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS18680
gene id: 446462:AMIR_RS18680
uniprot id: C6WD11
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

446462:AMIR RS16155
gene id: 446462:AMIR_RS16155
uniprot id: C6W8P0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

446462:AMIR RS25960
gene id: 446462:AMIR_RS25960
uniprot id: C6W8Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS07880
gene id: 446462:AMIR_RS07880
uniprot id: C6WBF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS25990
gene id: 446462:AMIR_RS25990
uniprot id: C6W8Z1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

446462:AMIR RS18805
gene id: 446462:AMIR_RS18805
uniprot id: C6WD34
names: Similarity
messages: Belongs to the group II decarboxylase family.

446462:AMIR RS25540
gene id: 446462:AMIR_RS25540
uniprot id: C6W8C5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

446462:AMIR RS32245
gene id: 446462:AMIR_RS32245
uniprot id: C6WLS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

446462:AMIR RS33330
gene id: 446462:AMIR_RS33330
uniprot id: C6WNG1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446462:AMIR RS09640
gene id: 446462:AMIR_RS09640
uniprot id: C6WFD7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS03285
gene id: 446462:AMIR_RS03285
uniprot id: C6WJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

446462:AMIR RS01340
gene id: 446462:AMIR_RS01340
uniprot id: C6WF99
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS31545
gene id: 446462:AMIR_RS31545
uniprot id: C6WKB6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS19715
gene id: 446462:AMIR_RS19715
uniprot id: C6WEM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

446462:AMIR RS32545
gene id: 446462:AMIR_RS32545
uniprot id: C6WLY3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

446462:AMIR RS09690
gene id: 446462:AMIR_RS09690
uniprot id: C6WFE7
names: Similarity
messages: Belongs to the universal stress protein A family.

446462:AMIR RS09695
gene id: 446462:AMIR_RS09695
uniprot id: C6WFE8
names: Similarity
messages: Belongs to the universal stress protein A family.

446462:AMIR RS00260
gene id: 446462:AMIR_RS00260
uniprot id: C6WDN1
names: Subcellular Location Annotation
messages: Periplasm

446462:AMIR RS02180
gene id: 446462:AMIR_RS02180
uniprot id: C6WHU8
names: Similarity
messages: Belongs to the AAA ATPase family.

446462:AMIR RS03140
gene id: 446462:AMIR_RS03140
uniprot id: C6WJF8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

446462:AMIR RS07235
gene id: 446462:AMIR_RS07235
uniprot id: C6WAC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS13935
gene id: 446462:AMIR_RS13935
uniprot id: C6WP49
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446462:AMIR RS16070
gene id: 446462:AMIR_RS16070
uniprot id: C6W8M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446462:AMIR RS17740
gene id: 446462:AMIR_RS17740
uniprot id: C6WAY0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS31485
gene id: 446462:AMIR_RS31485
uniprot id: C6WJ77
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06230
gene id: 446462:AMIR_RS06230
uniprot id: C6WRE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

446462:AMIR RS32685
gene id: 446462:AMIR_RS32685
uniprot id: C6WM12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

446462:AMIR RS33695
gene id: 446462:AMIR_RS33695
uniprot id: C6WPP5
names: Subcellular Location Annotation
messages: Cytoplasm

446462:AMIR RS20785
gene id: 446462:AMIR_RS20785
uniprot id: C6WHA9
names: Similarity
messages: Belongs to the peptidase S51 family.

446462:AMIR RS28220
gene id: 446462:AMIR_RS28220
uniprot id: C6WCC0
names: Similarity
messages: Belongs to the glutamate synthase family.

446462:AMIR RS20175
gene id: 446462:AMIR_RS20175
uniprot id: C6WFX3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS05330
gene id: 446462:AMIR_RS05330
uniprot id: C6WPW0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

446462:AMIR RS02565
gene id: 446462:AMIR_RS02565
uniprot id: C6WI25
names: Similarity
messages: Belongs to the citrate synthase family.

446462:AMIR RS15390
gene id: 446462:AMIR_RS15390
uniprot id: C6W7X3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

446462:AMIR RS27320
gene id: 446462:AMIR_RS27320
uniprot id: C6WB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

446462:AMIR RS35135
gene id: 446462:AMIR_RS35135
uniprot id: C6WSL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

446462:AMIR RS12305
gene id: 446462:AMIR_RS12305
uniprot id: C6WL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS06035
gene id: 446462:AMIR_RS06035
uniprot id: C6WRA5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

446462:AMIR RS31040
gene id: 446462:AMIR_RS31040
uniprot id: C6WIZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

446462:AMIR RS28095
gene id: 446462:AMIR_RS28095
uniprot id: C6WC95
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446462:AMIR RS28690
gene id: 446462:AMIR_RS28690
uniprot id: C6WDG6
names: Similarity
messages: Belongs to the FPG family.

446462:AMIR RS29290
gene id: 446462:AMIR_RS29290
uniprot id: C6WEU5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

446462:AMIR RS17745
gene id: 446462:AMIR_RS17745
uniprot id: C6WAY1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446462:AMIR RS07800
gene id: 446462:AMIR_RS07800
uniprot id: C6WBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

446462:AMIR RS29100
gene id: 446462:AMIR_RS29100
uniprot id: C6WEQ7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

446462:AMIR RS21005
gene id: 446462:AMIR_RS21005
uniprot id: C6WHF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS24365
gene id: 446462:AMIR_RS24365
uniprot id: C6WQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS07080
gene id: 446462:AMIR_RS07080
uniprot id: C6W9K1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

446462:AMIR RS16525
gene id: 446462:AMIR_RS16525
uniprot id: C6W8W5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446462:AMIR RS10285
gene id: 446462:AMIR_RS10285
uniprot id: C6WGS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS31470
gene id: 446462:AMIR_RS31470
uniprot id: C6WJ74
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446462:AMIR RS02325
gene id: 446462:AMIR_RS02325
uniprot id: C6WHX7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

446462:AMIR RS12695
gene id: 446462:AMIR_RS12695
uniprot id: C6WLC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

446462:AMIR RS10535
gene id: 446462:AMIR_RS10535
uniprot id: C6WGX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

446462:AMIR RS16420
gene id: 446462:AMIR_RS16420
uniprot id: C6W8U4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

446462:AMIR RS16065
gene id: 446462:AMIR_RS16065
uniprot id: C6W8M2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446462:AMIR RS05370
gene id: 446462:AMIR_RS05370
uniprot id: C6WPW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

446462:AMIR RS03645
gene id: 446462:AMIR_RS03645
uniprot id: C6WKT2
names: Similarity
messages: Belongs to the FBPase class 2 family.

446462:AMIR RS17320
gene id: 446462:AMIR_RS17320
uniprot id: C6WAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS34410
gene id: 446462:AMIR_RS34410
uniprot id: C6WR47
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS09580
gene id: 446462:AMIR_RS09580
uniprot id: C6WEB7
names: Similarity
messages: Belongs to the universal stress protein A family.

446462:AMIR RS26485
gene id: 446462:AMIR_RS26485
uniprot id: C6W992
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS23480
gene id: 446462:AMIR_RS23480
uniprot id: C6WN39
names: Similarity
messages: Belongs to the proline racemase family.

446462:AMIR RS10320
gene id: 446462:AMIR_RS10320
uniprot id: C6WGT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS01355
gene id: 446462:AMIR_RS01355
uniprot id: C6WFA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS12690
gene id: 446462:AMIR_RS12690
uniprot id: C6WLC0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS00120
gene id: 446462:AMIR_RS00120
uniprot id: C6WCH7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS25980
gene id: 446462:AMIR_RS25980
uniprot id: C6W8Y9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

446462:AMIR RS29045
gene id: 446462:AMIR_RS29045
uniprot id: C6WEP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS08965
gene id: 446462:AMIR_RS08965
uniprot id: C6WCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS26490
gene id: 446462:AMIR_RS26490
uniprot id: C6W993
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS05210
gene id: 446462:AMIR_RS05210
uniprot id: C6WNS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

446462:AMIR RS01025
gene id: 446462:AMIR_RS01025
uniprot id: C6WF41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

446462:AMIR RS22940
gene id: 446462:AMIR_RS22940
uniprot id: C6WLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS24105
gene id: 446462:AMIR_RS24105
uniprot id: C6WPH6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

446462:AMIR RS33085
gene id: 446462:AMIR_RS33085
uniprot id: C6WNB1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

446462:AMIR RS35025
gene id: 446462:AMIR_RS35025
uniprot id: C6WSJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

446462:AMIR RS01985
gene id: 446462:AMIR_RS01985
uniprot id: C6WGP3
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS09275
gene id: 446462:AMIR_RS09275
uniprot id: C6WE53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

446462:AMIR RS14470
gene id: 446462:AMIR_RS14470
uniprot id: C6WQG8
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS33070
gene id: 446462:AMIR_RS33070
uniprot id: C6WNA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

446462:AMIR RS10195
gene id: 446462:AMIR_RS10195
uniprot id: C6WFP4
names: Similarity
messages: Belongs to the peptidase S26 family.

446462:AMIR RS33855
gene id: 446462:AMIR_RS33855
uniprot id: C6WPS6
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

446462:AMIR RS18930
gene id: 446462:AMIR_RS18930
uniprot id: C6WD57
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

446462:AMIR RS05115
gene id: 446462:AMIR_RS05115
uniprot id: C6WNQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

446462:AMIR RS05155
gene id: 446462:AMIR_RS05155
uniprot id: C6WNR5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

446462:AMIR RS31220
gene id: 446462:AMIR_RS31220
uniprot id: C6WJ25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

446462:AMIR RS34325
gene id: 446462:AMIR_RS34325
uniprot id: C6WR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS32350
gene id: 446462:AMIR_RS32350
uniprot id: C6WLU4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

446462:AMIR RS13835
gene id: 446462:AMIR_RS13835
uniprot id: C6WP29
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446462:AMIR RS03735
gene id: 446462:AMIR_RS03735
uniprot id: C6WKV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

446462:AMIR RS00005
gene id: 446462:AMIR_RS00005
uniprot id: C6WCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

446462:AMIR RS01415
gene id: 446462:AMIR_RS01415
uniprot id: C6WFB3
names: Similarity
messages: Belongs to the GSP E family.

446462:AMIR RS21145
gene id: 446462:AMIR_RS21145
uniprot id: C6WIL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS07690
gene id: 446462:AMIR_RS07690
uniprot id: C6WAL5
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS03705
gene id: 446462:AMIR_RS03705
uniprot id: C6WKU4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

446462:AMIR RS34065
gene id: 446462:AMIR_RS34065
uniprot id: C6WQX6
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

446462:AMIR RS09365
gene id: 446462:AMIR_RS09365
uniprot id: C6WE71
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS11040
gene id: 446462:AMIR_RS11040
uniprot id: C6WIA1
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS18785
gene id: 446462:AMIR_RS18785
uniprot id: C6WD30
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS08710
gene id: 446462:AMIR_RS08710
uniprot id: C6WCR5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

446462:AMIR RS16185
gene id: 446462:AMIR_RS16185
uniprot id: C6W8P5
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS01130
gene id: 446462:AMIR_RS01130
uniprot id: C6WF59
names: Subcellular Location Annotation
messages: Cytoplasm

446462:AMIR RS10490
gene id: 446462:AMIR_RS10490
uniprot id: C6WGW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446462:AMIR RS03625
gene id: 446462:AMIR_RS03625
uniprot id: C6WKS8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

446462:AMIR RS02030
gene id: 446462:AMIR_RS02030
uniprot id: C6WGQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS28535
gene id: 446462:AMIR_RS28535
uniprot id: C6WDD4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

446462:AMIR RS17260
gene id: 446462:AMIR_RS17260
uniprot id: C6WAN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS14895
gene id: 446462:AMIR_RS14895
uniprot id: C6WRQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

446462:AMIR RS00405
gene id: 446462:AMIR_RS00405
uniprot id: C6WDR0
names: Similarity
messages: Belongs to the heme-containing dehydratase family.

446462:AMIR RS01030
gene id: 446462:AMIR_RS01030
uniprot id: C6WF42
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

446462:AMIR RS11745
gene id: 446462:AMIR_RS11745
uniprot id: C6WJQ9
names: Subcellular Location Annotation
messages: Cytoplasm

446462:AMIR RS05950
gene id: 446462:AMIR_RS05950
uniprot id: C6WR88
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

446462:AMIR RS11765
gene id: 446462:AMIR_RS11765
uniprot id: C6WJR3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

446462:AMIR RS11770
gene id: 446462:AMIR_RS11770
uniprot id: C6WJR4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

446462:AMIR RS13590
gene id: 446462:AMIR_RS13590
uniprot id: C6WNY3
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

446462:AMIR RS07260
gene id: 446462:AMIR_RS07260
uniprot id: C6WAD3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

446462:AMIR RS32565
gene id: 446462:AMIR_RS32565
uniprot id: C6WLY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446462:AMIR RS07110
gene id: 446462:AMIR_RS07110
uniprot id: C6WAA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

446462:AMIR RS34365
gene id: 446462:AMIR_RS34365
uniprot id: C6WR38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS22295
gene id: 446462:AMIR_RS22295
uniprot id: C6WKB0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS13125
gene id: 446462:AMIR_RS13125
uniprot id: C6WMN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS10385
gene id: 446462:AMIR_RS10385
uniprot id: C6WGU8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

446462:AMIR RS26025
gene id: 446462:AMIR_RS26025
uniprot id: C6W8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

446462:AMIR RS30105
gene id: 446462:AMIR_RS30105
uniprot id: C6WGB7
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

446462:AMIR RS23055
gene id: 446462:AMIR_RS23055
uniprot id: C6WMV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

446462:AMIR RS31125
gene id: 446462:AMIR_RS31125
uniprot id: C6WJ07
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

446462:AMIR RS03845
gene id: 446462:AMIR_RS03845
uniprot id: C6WKX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

446462:AMIR RS10350
gene id: 446462:AMIR_RS10350
uniprot id: C6WGU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

446462:AMIR RS12370
gene id: 446462:AMIR_RS12370
uniprot id: C6WL59
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS28085
gene id: 446462:AMIR_RS28085
uniprot id: C6WC93
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS23700
gene id: 446462:AMIR_RS23700
uniprot id: C6WP94
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

446462:AMIR RS25535
gene id: 446462:AMIR_RS25535
uniprot id: C6W8C4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

446462:AMIR RS15355
gene id: 446462:AMIR_RS15355
uniprot id: C6W7W6
names: Similarity
messages: Belongs to the asparagine synthetase family.

446462:AMIR RS29300
gene id: 446462:AMIR_RS29300
uniprot id: C6WEU7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

446462:AMIR RS32515
gene id: 446462:AMIR_RS32515
uniprot id: C6WLX7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

446462:AMIR RS21370
gene id: 446462:AMIR_RS21370
uniprot id: C6WIQ4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

446462:AMIR RS32040
gene id: 446462:AMIR_RS32040
uniprot id: C6WKL4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

446462:AMIR RS30200
gene id: 446462:AMIR_RS30200
uniprot id: C6WGD6
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS21830
gene id: 446462:AMIR_RS21830
uniprot id: C6WK21
names: Similarity
messages: Belongs to the terpene synthase family.

446462:AMIR RS30685
gene id: 446462:AMIR_RS30685
uniprot id: C6WHP7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

446462:AMIR RS27010
gene id: 446462:AMIR_RS27010
uniprot id: C6WA78
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

446462:AMIR RS22095
gene id: 446462:AMIR_RS22095
uniprot id: C6WK70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS09005
gene id: 446462:AMIR_RS09005
uniprot id: C6WCX6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS22510
gene id: 446462:AMIR_RS22510
uniprot id: C6WLH3
names: Similarity
messages: Belongs to the peptidase S1B family.

446462:AMIR RS15775
gene id: 446462:AMIR_RS15775
uniprot id: C6W847
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

446462:AMIR RS28550
gene id: 446462:AMIR_RS28550
uniprot id: C6WDD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

446462:AMIR RS07515
gene id: 446462:AMIR_RS07515
uniprot id: C6WAI2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

446462:AMIR RS35140
gene id: 446462:AMIR_RS35140
uniprot id: C6WSL2
names: Similarity
messages: Belongs to the ParB family.

446462:AMIR RS10895
gene id: 446462:AMIR_RS10895
uniprot id: C6WI74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS28125
gene id: 446462:AMIR_RS28125
uniprot id: C6WCA1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS23530
gene id: 446462:AMIR_RS23530
uniprot id: C6WN49
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446462:AMIR RS32715
gene id: 446462:AMIR_RS32715
uniprot id: C6WM18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

446462:AMIR RS20820
gene id: 446462:AMIR_RS20820
uniprot id: C6WHB6
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

446462:AMIR RS32995
gene id: 446462:AMIR_RS32995
uniprot id: C6WN92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS33475
gene id: 446462:AMIR_RS33475
uniprot id: C6WPK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

446462:AMIR RS30765
gene id: 446462:AMIR_RS30765
uniprot id: C6WHR3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

446462:AMIR RS28620
gene id: 446462:AMIR_RS28620
uniprot id: C6WDF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

446462:AMIR RS40505
gene id: 446462:AMIR_RS40505
uniprot id: C6WKB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

446462:AMIR RS30565
gene id: 446462:AMIR_RS30565
uniprot id: C6WHM2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

446462:AMIR RS15800
gene id: 446462:AMIR_RS15800
uniprot id: C6W852
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS02285
gene id: 446462:AMIR_RS02285
uniprot id: C6WHW9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

446462:AMIR RS06770
gene id: 446462:AMIR_RS06770
uniprot id: C6W9D9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446462:AMIR RS12645
gene id: 446462:AMIR_RS12645
uniprot id: C6WLB1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

446462:AMIR RS21055
gene id: 446462:AMIR_RS21055
uniprot id: C6WIJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

446462:AMIR RS19035
gene id: 446462:AMIR_RS19035
uniprot id: C6WD78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS33200
gene id: 446462:AMIR_RS33200
uniprot id: C6WND5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

446462:AMIR RS28510
gene id: 446462:AMIR_RS28510
uniprot id: C6WDC9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

446462:AMIR RS10575
gene id: 446462:AMIR_RS10575
uniprot id: C6WGY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

446462:AMIR RS33045
gene id: 446462:AMIR_RS33045
uniprot id: C6WNA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

446462:AMIR RS11225
gene id: 446462:AMIR_RS11225
uniprot id: C6WID6
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

446462:AMIR RS17645
gene id: 446462:AMIR_RS17645
uniprot id: C6WAW1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

446462:AMIR RS35155
gene id: 446462:AMIR_RS35155
uniprot id: C6WSL5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446462:AMIR RS01360
gene id: 446462:AMIR_RS01360
uniprot id: C6WFA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS04950
gene id: 446462:AMIR_RS04950
uniprot id: C6WNM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

446462:AMIR RS24820
gene id: 446462:AMIR_RS24820
uniprot id: C6WS04
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446462:AMIR RS07270
gene id: 446462:AMIR_RS07270
uniprot id: C6WAD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS01145
gene id: 446462:AMIR_RS01145
uniprot id: C6WF62
names: Similarity
messages: Belongs to the OsmC/Ohr family.

446462:AMIR RS33075
gene id: 446462:AMIR_RS33075
uniprot id: C6WNA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446462:AMIR RS34110
gene id: 446462:AMIR_RS34110
uniprot id: C6WQY5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

446462:AMIR RS29130
gene id: 446462:AMIR_RS29130
uniprot id: C6WER3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS35465
gene id: 446462:AMIR_RS35465
uniprot id: C6WGZ5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

446462:AMIR RS33055
gene id: 446462:AMIR_RS33055
uniprot id: C6WNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446462:AMIR RS40875
gene id: 446462:AMIR_RS40875
uniprot id: C6WKQ9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS11020
gene id: 446462:AMIR_RS11020
uniprot id: C6WI99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

446462:AMIR RS22910
gene id: 446462:AMIR_RS22910
uniprot id: C6WLP5
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS23440
gene id: 446462:AMIR_RS23440
uniprot id: C6WN31
names: Similarity
messages: Belongs to the peptidase S33 family.

446462:AMIR RS33095
gene id: 446462:AMIR_RS33095
uniprot id: C6WNB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446462:AMIR RS29005
gene id: 446462:AMIR_RS29005
uniprot id: C6WDM7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446462:AMIR RS11215
gene id: 446462:AMIR_RS11215
uniprot id: C6WID4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446462:AMIR RS28295
gene id: 446462:AMIR_RS28295
uniprot id: C6WCD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

446462:AMIR RS27745
gene id: 446462:AMIR_RS27745
uniprot id: C6WBC5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446462:AMIR RS29285
gene id: 446462:AMIR_RS29285
uniprot id: C6WEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

446462:AMIR RS13540
gene id: 446462:AMIR_RS13540
uniprot id: C6WNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS19815
gene id: 446462:AMIR_RS19815
uniprot id: C6WFQ7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS29940
gene id: 446462:AMIR_RS29940
uniprot id: C6WG83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS06055
gene id: 446462:AMIR_RS06055
uniprot id: C6WRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS09130
gene id: 446462:AMIR_RS09130
uniprot id: C6WE25
names: Similarity
messages: Belongs to the peptidase C40 family.

446462:AMIR RS29855
gene id: 446462:AMIR_RS29855
uniprot id: C6WG66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

446462:AMIR RS03080
gene id: 446462:AMIR_RS03080
uniprot id: C6WJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS29405
gene id: 446462:AMIR_RS29405
uniprot id: C6WEW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS19020
gene id: 446462:AMIR_RS19020
uniprot id: C6WD75
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS14415
gene id: 446462:AMIR_RS14415
uniprot id: C6WQF6
names: Similarity
messages: Belongs to the TrpF family.

446462:AMIR RS19355
gene id: 446462:AMIR_RS19355
uniprot id: C6WEG0
names: Similarity
messages: Belongs to the acyltransferase PapA5 family.

446462:AMIR RS13860
gene id: 446462:AMIR_RS13860
uniprot id: C6WP34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446462:AMIR RS28050
gene id: 446462:AMIR_RS28050
uniprot id: C6WC86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS07730
gene id: 446462:AMIR_RS07730
uniprot id: C6WAM2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446462:AMIR RS22860
gene id: 446462:AMIR_RS22860
uniprot id: C6WLN6
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS09855
gene id: 446462:AMIR_RS09855
uniprot id: C6WFI1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS05730
gene id: 446462:AMIR_RS05730
uniprot id: C6WQ41
names: Similarity
messages: Belongs to the peptidase M1 family.

446462:AMIR RS23745
gene id: 446462:AMIR_RS23745
uniprot id: C6WPA3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS20845
gene id: 446462:AMIR_RS20845
uniprot id: C6WHC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

446462:AMIR RS14395
gene id: 446462:AMIR_RS14395
uniprot id: C6WQF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS32630
gene id: 446462:AMIR_RS32630
uniprot id: C6WM00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

446462:AMIR RS01710
gene id: 446462:AMIR_RS01710
uniprot id: C6WGI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

446462:AMIR RS34290
gene id: 446462:AMIR_RS34290
uniprot id: C6WR23
names: Similarity
messages: Belongs to the YciI family.

446462:AMIR RS35180
gene id: 446462:AMIR_RS35180
uniprot id: C6WSM0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

446462:AMIR RS29185
gene id: 446462:AMIR_RS29185
uniprot id: C6WES4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS09085
gene id: 446462:AMIR_RS09085
uniprot id: C6WE16
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

446462:AMIR RS32910
gene id: 446462:AMIR_RS32910
uniprot id: C6WN77
names: Similarity
messages: Belongs to the MmpS family.

446462:AMIR RS13180
gene id: 446462:AMIR_RS13180
uniprot id: C6WMP4
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

446462:AMIR RS04795
gene id: 446462:AMIR_RS04795
uniprot id: C6WNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

446462:AMIR RS24520
gene id: 446462:AMIR_RS24520
uniprot id: C6WQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

446462:AMIR RS11265
gene id: 446462:AMIR_RS11265
uniprot id: C6WIE4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

446462:AMIR RS12390
gene id: 446462:AMIR_RS12390
uniprot id: C6WL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

446462:AMIR RS13300
gene id: 446462:AMIR_RS13300
uniprot id: C6WMR8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

446462:AMIR RS04010
gene id: 446462:AMIR_RS04010
uniprot id: C6WL05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

446462:AMIR RS19400
gene id: 446462:AMIR_RS19400
uniprot id: C6WEG8
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS17800
gene id: 446462:AMIR_RS17800
uniprot id: C6WAZ2
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446462:AMIR RS21525
gene id: 446462:AMIR_RS21525
uniprot id: C6WIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS32620
gene id: 446462:AMIR_RS32620
uniprot id: C6WLZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

446462:AMIR RS26960
gene id: 446462:AMIR_RS26960
uniprot id: C6WA70
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS04295
gene id: 446462:AMIR_RS04295
uniprot id: C6WM85
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS20910
gene id: 446462:AMIR_RS20910
uniprot id: C6WHD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

446462:AMIR RS07390
gene id: 446462:AMIR_RS07390
uniprot id: C6WAF9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

446462:AMIR RS05630
gene id: 446462:AMIR_RS05630
uniprot id: C6WQ21
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

446462:AMIR RS02530
gene id: 446462:AMIR_RS02530
uniprot id: C6WI18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

446462:AMIR RS13815
gene id: 446462:AMIR_RS13815
uniprot id: C6WP24
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS30965
gene id: 446462:AMIR_RS30965
uniprot id: C6WIX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446462:AMIR RS04390
gene id: 446462:AMIR_RS04390
uniprot id: C6WMA5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS03805
gene id: 446462:AMIR_RS03805
uniprot id: C6WKW4
names: Similarity
messages: Belongs to the YciI family.

446462:AMIR RS24175
gene id: 446462:AMIR_RS24175
uniprot id: C6WQK1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS29385
gene id: 446462:AMIR_RS29385
uniprot id: C6WEW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

446462:AMIR RS12830
gene id: 446462:AMIR_RS12830
uniprot id: C6WMH3
names: Similarity
messages: Belongs to the DSD1 family.

446462:AMIR RS13430
gene id: 446462:AMIR_RS13430
uniprot id: C6WNV1
names: Similarity
messages: Belongs to the peptidase S33 family.

446462:AMIR RS01580
gene id: 446462:AMIR_RS01580
uniprot id: C6WGG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

446462:AMIR RS31460
gene id: 446462:AMIR_RS31460
uniprot id: C6WJ72
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

446462:AMIR RS20675
gene id: 446462:AMIR_RS20675
uniprot id: C6WH88
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

446462:AMIR RS34070
gene id: 446462:AMIR_RS34070
uniprot id: C6WQX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

446462:AMIR RS23840
gene id: 446462:AMIR_RS23840
uniprot id: C6WPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

446462:AMIR RS09825
gene id: 446462:AMIR_RS09825
uniprot id: C6WFH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

446462:AMIR RS25555
gene id: 446462:AMIR_RS25555
uniprot id: C6W8C8
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

446462:AMIR RS28315
gene id: 446462:AMIR_RS28315
uniprot id: C6WCD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

446462:AMIR RS11240
gene id: 446462:AMIR_RS11240
uniprot id: C6WID9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

446462:AMIR RS00420
gene id: 446462:AMIR_RS00420
uniprot id: C6WDR3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS04760
gene id: 446462:AMIR_RS04760
uniprot id: C6WNI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

446462:AMIR RS28590
gene id: 446462:AMIR_RS28590
uniprot id: C6WDE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

446462:AMIR RS29415
gene id: 446462:AMIR_RS29415
uniprot id: C6WEW9
names: Similarity
messages: Belongs to the allantoicase family.

446462:AMIR RS15040
gene id: 446462:AMIR_RS15040
uniprot id: C6WRT5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS21520
gene id: 446462:AMIR_RS21520
uniprot id: C6WIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS31780
gene id: 446462:AMIR_RS31780
uniprot id: C6WKG1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

446462:AMIR RS06320
gene id: 446462:AMIR_RS06320
uniprot id: C6WRG1
names: Similarity
messages: Belongs to the Fur family.

446462:AMIR RS05120
gene id: 446462:AMIR_RS05120
uniprot id: C6WNQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

446462:AMIR RS00180
gene id: 446462:AMIR_RS00180
uniprot id: C6WCI8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS11640
gene id: 446462:AMIR_RS11640
uniprot id: C6WJN8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446462:AMIR RS11230
gene id: 446462:AMIR_RS11230
uniprot id: C6WID7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

446462:AMIR RS02560
gene id: 446462:AMIR_RS02560
uniprot id: C6WI24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

446462:AMIR RS29835
gene id: 446462:AMIR_RS29835
uniprot id: C6WG62
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS08650
gene id: 446462:AMIR_RS08650
uniprot id: C6WCQ3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06670
gene id: 446462:AMIR_RS06670
uniprot id: C6W9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

446462:AMIR RS32680
gene id: 446462:AMIR_RS32680
uniprot id: C6WM11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

446462:AMIR RS30425
gene id: 446462:AMIR_RS30425
uniprot id: C6WHJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

446462:AMIR RS02195
gene id: 446462:AMIR_RS02195
uniprot id: C6WHV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

446462:AMIR RS12205
gene id: 446462:AMIR_RS12205
uniprot id: C6WL25
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

446462:AMIR RS30090
gene id: 446462:AMIR_RS30090
uniprot id: C6WGB4
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

446462:AMIR RS02555
gene id: 446462:AMIR_RS02555
uniprot id: C6WI23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

446462:AMIR RS02755
gene id: 446462:AMIR_RS02755
uniprot id: C6WI62
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS11720
gene id: 446462:AMIR_RS11720
uniprot id: C6WJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

446462:AMIR RS05520
gene id: 446462:AMIR_RS05520
uniprot id: C6WPZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

446462:AMIR RS21405
gene id: 446462:AMIR_RS21405
uniprot id: C6WIR1
names: Similarity
messages: Belongs to the peptidase S1 family.

446462:AMIR RS18460
gene id: 446462:AMIR_RS18460
uniprot id: C6WC20
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

446462:AMIR RS07640
gene id: 446462:AMIR_RS07640
uniprot id: C6WAK7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

446462:AMIR RS27680
gene id: 446462:AMIR_RS27680
uniprot id: C6WBB2
names: Similarity
messages: Belongs to the DprA/Smf family.

446462:AMIR RS00630
gene id: 446462:AMIR_RS00630
uniprot id: C6WDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

446462:AMIR RS03710
gene id: 446462:AMIR_RS03710
uniprot id: C6WKU5
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

446462:AMIR RS06890
gene id: 446462:AMIR_RS06890
uniprot id: C6W9G3
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

446462:AMIR RS05705
gene id: 446462:AMIR_RS05705
uniprot id: C6WQ36
names: Similarity
messages: Belongs to the peptidase S9A family.

446462:AMIR RS04885
gene id: 446462:AMIR_RS04885
uniprot id: C6WNL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS06295
gene id: 446462:AMIR_RS06295
uniprot id: C6WRF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

446462:AMIR RS05090
gene id: 446462:AMIR_RS05090
uniprot id: C6WNQ2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

446462:AMIR RS28545
gene id: 446462:AMIR_RS28545
uniprot id: C6WDD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

446462:AMIR RS08630
gene id: 446462:AMIR_RS08630
uniprot id: C6WCP9
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS02240
gene id: 446462:AMIR_RS02240
uniprot id: C6WHW0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS12300
gene id: 446462:AMIR_RS12300
uniprot id: C6WL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS24480
gene id: 446462:AMIR_RS24480
uniprot id: C6WQR5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS34270
gene id: 446462:AMIR_RS34270
uniprot id: C6WR19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

446462:AMIR RS20880
gene id: 446462:AMIR_RS20880
uniprot id: C6WHC8
names: Similarity
messages: Belongs to the Fur family.

446462:AMIR RS02460
gene id: 446462:AMIR_RS02460
uniprot id: C6WI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

446462:AMIR RS33090
gene id: 446462:AMIR_RS33090
uniprot id: C6WNB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

446462:AMIR RS24305
gene id: 446462:AMIR_RS24305
uniprot id: C6WQM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS26100
gene id: 446462:AMIR_RS26100
uniprot id: C6W913
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

446462:AMIR RS01800
gene id: 446462:AMIR_RS01800
uniprot id: C6WGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS19795
gene id: 446462:AMIR_RS19795
uniprot id: C6WEN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

446462:AMIR RS00725
gene id: 446462:AMIR_RS00725
uniprot id: C6WDW9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

446462:AMIR RS33160
gene id: 446462:AMIR_RS33160
uniprot id: C6WNC7
names: Similarity
messages: Belongs to the isochorismate synthase family.

446462:AMIR RS04280
gene id: 446462:AMIR_RS04280
uniprot id: C6WM82
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS31930
gene id: 446462:AMIR_RS31930
uniprot id: C6WKJ2
names: Similarity
messages: Belongs to the peptidase C40 family.

446462:AMIR RS34885
gene id: 446462:AMIR_RS34885
uniprot id: C6WSG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

446462:AMIR RS10900
gene id: 446462:AMIR_RS10900
uniprot id: C6WI75
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446462:AMIR RS03685
gene id: 446462:AMIR_RS03685
uniprot id: C6WKU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

446462:AMIR RS07195
gene id: 446462:AMIR_RS07195
uniprot id: C6WAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

446462:AMIR RS32740
gene id: 446462:AMIR_RS32740
uniprot id: C6WM23
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

446462:AMIR RS09525
gene id: 446462:AMIR_RS09525
uniprot id: C6WEA4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

446462:AMIR RS01775
gene id: 446462:AMIR_RS01775
uniprot id: C6WGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS30240
gene id: 446462:AMIR_RS30240
uniprot id: C6WGE4
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

446462:AMIR RS33615
gene id: 446462:AMIR_RS33615
uniprot id: C6WPN2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS23470
gene id: 446462:AMIR_RS23470
uniprot id: C6WN37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS03570
gene id: 446462:AMIR_RS03570
uniprot id: C6WKR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

446462:AMIR RS11495
gene id: 446462:AMIR_RS11495
uniprot id: C6WII9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS16370
gene id: 446462:AMIR_RS16370
uniprot id: C6W8T4
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS13660
gene id: 446462:AMIR_RS13660
uniprot id: C6WNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS01370
gene id: 446462:AMIR_RS01370
uniprot id: C6WFA5
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

446462:AMIR RS26970
gene id: 446462:AMIR_RS26970
uniprot id: C6WA73
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

446462:AMIR RS35110
gene id: 446462:AMIR_RS35110
uniprot id: C6WSK6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

446462:AMIR RS28950
gene id: 446462:AMIR_RS28950
uniprot id: C6WDL6
names: Similarity
messages: Belongs to the UPF0047 family.

446462:AMIR RS06740
gene id: 446462:AMIR_RS06740
uniprot id: C6W9D3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS04745
gene id: 446462:AMIR_RS04745
uniprot id: C6WNI4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

446462:AMIR RS18620
gene id: 446462:AMIR_RS18620
uniprot id: C6WCZ9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS05890
gene id: 446462:AMIR_RS05890
uniprot id: C6WQ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS06390
gene id: 446462:AMIR_RS06390
uniprot id: C6WRH5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

446462:AMIR RS30925
gene id: 446462:AMIR_RS30925
uniprot id: C6WIW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

446462:AMIR RS27045
gene id: 446462:AMIR_RS27045
uniprot id: C6WA85
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

446462:AMIR RS24765
gene id: 446462:AMIR_RS24765
uniprot id: C6WRZ3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

446462:AMIR RS16075
gene id: 446462:AMIR_RS16075
uniprot id: C6W8M4
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

446462:AMIR RS32760
gene id: 446462:AMIR_RS32760
uniprot id: C6WM27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

446462:AMIR RS32865
gene id: 446462:AMIR_RS32865
uniprot id: C6WN69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

446462:AMIR RS16855
gene id: 446462:AMIR_RS16855
uniprot id: C6W9Q9
names: Similarity
messages: Belongs to the TPP enzyme family.

446462:AMIR RS12345
gene id: 446462:AMIR_RS12345
uniprot id: C6WL54
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

446462:AMIR RS05850
gene id: 446462:AMIR_RS05850
uniprot id: C6WQ64
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

446462:AMIR RS07150
gene id: 446462:AMIR_RS07150
uniprot id: C6WAB2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

446462:AMIR RS06775
gene id: 446462:AMIR_RS06775
uniprot id: C6W9E0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

446462:AMIR RS00770
gene id: 446462:AMIR_RS00770
uniprot id: C6WDX7
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS14235
gene id: 446462:AMIR_RS14235
uniprot id: C6WQC1
names: Similarity
messages: Belongs to the TPP enzyme family.

446462:AMIR RS29085
gene id: 446462:AMIR_RS29085
uniprot id: C6WEQ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

446462:AMIR RS23990
gene id: 446462:AMIR_RS23990
uniprot id: C6WPF2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

446462:AMIR RS22935
gene id: 446462:AMIR_RS22935
uniprot id: C6WLQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS32225
gene id: 446462:AMIR_RS32225
uniprot id: C6WLR8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

446462:AMIR RS18435
gene id: 446462:AMIR_RS18435
uniprot id: C6WC15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS03990
gene id: 446462:AMIR_RS03990
uniprot id: C6WL01
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS06200
gene id: 446462:AMIR_RS06200
uniprot id: C6WRD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

446462:AMIR RS22915
gene id: 446462:AMIR_RS22915
uniprot id: C6WLP6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

446462:AMIR RS25735
gene id: 446462:AMIR_RS25735
uniprot id: C6W8G3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS01010
gene id: 446462:AMIR_RS01010
uniprot id: C6WF38
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446462:AMIR RS11630
gene id: 446462:AMIR_RS11630
uniprot id: C6WJN6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

446462:AMIR RS13040
gene id: 446462:AMIR_RS13040
uniprot id: C6WML7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

446462:AMIR RS29730
gene id: 446462:AMIR_RS29730
uniprot id: C6WG43
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

446462:AMIR RS05810
gene id: 446462:AMIR_RS05810
uniprot id: C6WQ55
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

446462:AMIR RS34075
gene id: 446462:AMIR_RS34075
uniprot id: C6WQX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

446462:AMIR RS08635
gene id: 446462:AMIR_RS08635
uniprot id: C6WCQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS22355
gene id: 446462:AMIR_RS22355
uniprot id: C6WLE2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS05180
gene id: 446462:AMIR_RS05180
uniprot id: C6WNR9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS29370
gene id: 446462:AMIR_RS29370
uniprot id: C6WEW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

446462:AMIR RS28355
gene id: 446462:AMIR_RS28355
uniprot id: C6WCE8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

446462:AMIR RS36390
gene id: 446462:AMIR_RS36390
uniprot id: C6WG68
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS35150
gene id: 446462:AMIR_RS35150
uniprot id: C6WSL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

446462:AMIR RS06985
gene id: 446462:AMIR_RS06985
uniprot id: C6W9I2
names: Caution
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS25725
gene id: 446462:AMIR_RS25725
uniprot id: C6W8G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

446462:AMIR RS32400
gene id: 446462:AMIR_RS32400
uniprot id: C6WLV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS34425
gene id: 446462:AMIR_RS34425
uniprot id: C6WR50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

446462:AMIR RS34430
gene id: 446462:AMIR_RS34430
uniprot id: C6WR51
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

446462:AMIR RS19025
gene id: 446462:AMIR_RS19025
uniprot id: C6WD76
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS02575
gene id: 446462:AMIR_RS02575
uniprot id: C6WI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS21920
gene id: 446462:AMIR_RS21920
uniprot id: C6WK38
names: Similarity
messages: Belongs to the UPF0098 family.

446462:AMIR RS30020
gene id: 446462:AMIR_RS30020
uniprot id: C6WGA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

446462:AMIR RS34590
gene id: 446462:AMIR_RS34590
uniprot id: C6WR81
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

446462:AMIR RS10960
gene id: 446462:AMIR_RS10960
uniprot id: C6WI87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS29345
gene id: 446462:AMIR_RS29345
uniprot id: C6WEV5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

446462:AMIR RS22445
gene id: 446462:AMIR_RS22445
uniprot id: C6WLG0
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32605
gene id: 446462:AMIR_RS32605
uniprot id: C6WLZ5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

446462:AMIR RS08725
gene id: 446462:AMIR_RS08725
uniprot id: C6WCR8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

446462:AMIR RS29810
gene id: 446462:AMIR_RS29810
uniprot id: C6WG56
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

446462:AMIR RS05835
gene id: 446462:AMIR_RS05835
uniprot id: C6WQ61
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

446462:AMIR RS30820
gene id: 446462:AMIR_RS30820
uniprot id: C6WHS4
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS27075
gene id: 446462:AMIR_RS27075
uniprot id: C6WA91
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

446462:AMIR RS33605
gene id: 446462:AMIR_RS33605
uniprot id: C6WPM9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06995
gene id: 446462:AMIR_RS06995
uniprot id: C6W9I4
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

446462:AMIR RS15285
gene id: 446462:AMIR_RS15285
uniprot id: C6WRY2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS25985
gene id: 446462:AMIR_RS25985
uniprot id: C6W8Z0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS01660
gene id: 446462:AMIR_RS01660
uniprot id: C6WGH9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

446462:AMIR RS13175
gene id: 446462:AMIR_RS13175
uniprot id: C6WMP3
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

446462:AMIR RS24145
gene id: 446462:AMIR_RS24145
uniprot id: C6WPI3
names: Similarity
messages: Belongs to the TPP enzyme family.

446462:AMIR RS17885
gene id: 446462:AMIR_RS17885
uniprot id: C6WBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

446462:AMIR RS03830
gene id: 446462:AMIR_RS03830
uniprot id: C6WKX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS03220
gene id: 446462:AMIR_RS03220
uniprot id: C6WJH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

446462:AMIR RS11785
gene id: 446462:AMIR_RS11785
uniprot id: C6WJR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

446462:AMIR RS22830
gene id: 446462:AMIR_RS22830
uniprot id: C6WLN0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

446462:AMIR RS30060
gene id: 446462:AMIR_RS30060
uniprot id: C6WGA8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

446462:AMIR RS30140
gene id: 446462:AMIR_RS30140
uniprot id: C6WGC4
names: Similarity
messages: Belongs to the UPF0045 family.

446462:AMIR RS03810
gene id: 446462:AMIR_RS03810
uniprot id: C6WKW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS06285
gene id: 446462:AMIR_RS06285
uniprot id: C6WRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS10740
gene id: 446462:AMIR_RS10740
uniprot id: C6WH18
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS21980
gene id: 446462:AMIR_RS21980
uniprot id: C6WK49
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

446462:AMIR RS32745
gene id: 446462:AMIR_RS32745
uniprot id: C6WM24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

446462:AMIR RS25855
gene id: 446462:AMIR_RS25855
uniprot id: C6W8I8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS03660
gene id: 446462:AMIR_RS03660
uniprot id: C6WKT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

446462:AMIR RS17890
gene id: 446462:AMIR_RS17890
uniprot id: C6WBR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

446462:AMIR RS17895
gene id: 446462:AMIR_RS17895
uniprot id: C6WBR3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS12525
gene id: 446462:AMIR_RS12525
uniprot id: C6WL88
names: Similarity
messages: Belongs to the YciI family.

446462:AMIR RS25630
gene id: 446462:AMIR_RS25630
uniprot id: C6W8E2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS08860
gene id: 446462:AMIR_RS08860
uniprot id: C6WCU6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

446462:AMIR RS02520
gene id: 446462:AMIR_RS02520
uniprot id: C6WI16
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

446462:AMIR RS32690
gene id: 446462:AMIR_RS32690
uniprot id: C6WM13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

446462:AMIR RS17790
gene id: 446462:AMIR_RS17790
uniprot id: C6WAZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446462:AMIR RS31050
gene id: 446462:AMIR_RS31050
uniprot id: C6WIZ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

446462:AMIR RS28585
gene id: 446462:AMIR_RS28585
uniprot id: C6WDE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

446462:AMIR RS34655
gene id: 446462:AMIR_RS34655
uniprot id: C6WSB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

446462:AMIR RS00675
gene id: 446462:AMIR_RS00675
uniprot id: C6WDV9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

446462:AMIR RS10645
gene id: 446462:AMIR_RS10645
uniprot id: C6WGZ9
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

446462:AMIR RS04060
gene id: 446462:AMIR_RS04060
uniprot id: C6WM36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS03150
gene id: 446462:AMIR_RS03150
uniprot id: C6WJG0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

446462:AMIR RS05385
gene id: 446462:AMIR_RS05385
uniprot id: C6WPX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446462:AMIR RS24940
gene id: 446462:AMIR_RS24940
uniprot id: C6WS29
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS10240
gene id: 446462:AMIR_RS10240
uniprot id: C6WFQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

446462:AMIR RS16990
gene id: 446462:AMIR_RS16990
uniprot id: C6W9T5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446462:AMIR RS32425
gene id: 446462:AMIR_RS32425
uniprot id: C6WLV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

446462:AMIR RS24780
gene id: 446462:AMIR_RS24780
uniprot id: C6WRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS00020
gene id: 446462:AMIR_RS00020
uniprot id: C6WCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

446462:AMIR RS14600
gene id: 446462:AMIR_RS14600
uniprot id: C6WQI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS26770
gene id: 446462:AMIR_RS26770
uniprot id: C6WA32
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

446462:AMIR RS03095
gene id: 446462:AMIR_RS03095
uniprot id: C6WJE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

446462:AMIR RS25745
gene id: 446462:AMIR_RS25745
uniprot id: C6W8G5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

446462:AMIR RS30400
gene id: 446462:AMIR_RS30400
uniprot id: C6WHJ1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

446462:AMIR RS01120
gene id: 446462:AMIR_RS01120
uniprot id: C6WF57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS20885
gene id: 446462:AMIR_RS20885
uniprot id: C6WHC9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS12860
gene id: 446462:AMIR_RS12860
uniprot id: C6WMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 3 family.
messages: Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action. In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.
messages: Secreted

446462:AMIR RS28525
gene id: 446462:AMIR_RS28525
uniprot id: C6WDD2
names: Similarity
messages: Belongs to the YggT family.

446462:AMIR RS22050
gene id: 446462:AMIR_RS22050
uniprot id: C6WK62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS00030
gene id: 446462:AMIR_RS00030
uniprot id: C6WCF9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

446462:AMIR RS15925
gene id: 446462:AMIR_RS15925
uniprot id: C6W877
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS29675
gene id: 446462:AMIR_RS29675
uniprot id: C6WG31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

446462:AMIR RS14265
gene id: 446462:AMIR_RS14265
uniprot id: C6WQC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS29660
gene id: 446462:AMIR_RS29660
uniprot id: C6WG28
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

446462:AMIR RS29575
gene id: 446462:AMIR_RS29575
uniprot id: C6WF01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

446462:AMIR RS19590
gene id: 446462:AMIR_RS19590
uniprot id: C6WEK2
names: Similarity
messages: Belongs to the NodU/CmcH family.

446462:AMIR RS10755
gene id: 446462:AMIR_RS10755
uniprot id: C6WH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

446462:AMIR RS05040
gene id: 446462:AMIR_RS05040
uniprot id: C6WNP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

446462:AMIR RS32700
gene id: 446462:AMIR_RS32700
uniprot id: C6WM15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

446462:AMIR RS10050
gene id: 446462:AMIR_RS10050
uniprot id: C6WFM0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

446462:AMIR RS07810
gene id: 446462:AMIR_RS07810
uniprot id: C6WBD7
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS10410
gene id: 446462:AMIR_RS10410
uniprot id: C6WGV3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS08700
gene id: 446462:AMIR_RS08700
uniprot id: C6WCR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

446462:AMIR RS24275
gene id: 446462:AMIR_RS24275
uniprot id: C6WQM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS12055
gene id: 446462:AMIR_RS12055
uniprot id: C6WJX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS05740
gene id: 446462:AMIR_RS05740
uniprot id: C6WQ43
names: Similarity
messages: Belongs to the ComB family.

446462:AMIR RS34680
gene id: 446462:AMIR_RS34680
uniprot id: C6WSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446462:AMIR RS22500
gene id: 446462:AMIR_RS22500
uniprot id: C6WLH1
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS06025
gene id: 446462:AMIR_RS06025
uniprot id: C6WRA3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS28145
gene id: 446462:AMIR_RS28145
uniprot id: C6WCA5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446462:AMIR RS06220
gene id: 446462:AMIR_RS06220
uniprot id: C6WRE1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

446462:AMIR RS35000
gene id: 446462:AMIR_RS35000
uniprot id: C6WSI5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

446462:AMIR RS14375
gene id: 446462:AMIR_RS14375
uniprot id: C6WQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS29600
gene id: 446462:AMIR_RS29600
uniprot id: C6WF06
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

446462:AMIR RS35165
gene id: 446462:AMIR_RS35165
uniprot id: C6WSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

446462:AMIR RS19825
gene id: 446462:AMIR_RS19825
uniprot id: C6WFQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

446462:AMIR RS18085
gene id: 446462:AMIR_RS18085
uniprot id: C6WBV1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS14170
gene id: 446462:AMIR_RS14170
uniprot id: C6WQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS11735
gene id: 446462:AMIR_RS11735
uniprot id: C6WJQ7
names: Similarity
messages: Belongs to the peptidase C40 family.
messages: Belongs to the transglycosylase Slt family.

446462:AMIR RS01425
gene id: 446462:AMIR_RS01425
uniprot id: C6WFB5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS34185
gene id: 446462:AMIR_RS34185
uniprot id: C6WR00
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS06805
gene id: 446462:AMIR_RS06805
uniprot id: C6W9E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446462:AMIR RS15215
gene id: 446462:AMIR_RS15215
uniprot id: C6WRW9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS30520
gene id: 446462:AMIR_RS30520
uniprot id: C6WHL4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

446462:AMIR RS09715
gene id: 446462:AMIR_RS09715
uniprot id: C6WFF2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS33340
gene id: 446462:AMIR_RS33340
uniprot id: C6WNG3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

446462:AMIR RS08920
gene id: 446462:AMIR_RS08920
uniprot id: C6WCV9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446462:AMIR RS03380
gene id: 446462:AMIR_RS03380
uniprot id: C6WJK2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

446462:AMIR RS28140
gene id: 446462:AMIR_RS28140
uniprot id: C6WCA4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446462:AMIR RS03535
gene id: 446462:AMIR_RS03535
uniprot id: C6WKR0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446462:AMIR RS27040
gene id: 446462:AMIR_RS27040
uniprot id: C6WA84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

446462:AMIR RS35100
gene id: 446462:AMIR_RS35100
uniprot id: C6WSK4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS32395
gene id: 446462:AMIR_RS32395
uniprot id: C6WLV3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS06810
gene id: 446462:AMIR_RS06810
uniprot id: C6W9E7
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

446462:AMIR RS00650
gene id: 446462:AMIR_RS00650
uniprot id: C6WDV4
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

446462:AMIR RS28165
gene id: 446462:AMIR_RS28165
uniprot id: C6WCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

446462:AMIR RS18695
gene id: 446462:AMIR_RS18695
uniprot id: C6WD14
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

446462:AMIR RS33405
gene id: 446462:AMIR_RS33405
uniprot id: C6WPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

446462:AMIR RS17230
gene id: 446462:AMIR_RS17230
uniprot id: C6WAN2
names: Similarity
messages: Belongs to the peptidase S66 family.

446462:AMIR RS18035
gene id: 446462:AMIR_RS18035
uniprot id: C6WBU1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06365
gene id: 446462:AMIR_RS06365
uniprot id: C6WRH0
names: Similarity
messages: Belongs to the serpin family.

446462:AMIR RS31475
gene id: 446462:AMIR_RS31475
uniprot id: C6WJ75
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

446462:AMIR RS09340
gene id: 446462:AMIR_RS09340
uniprot id: C6WE66
names: Similarity
messages: Belongs to the ribulokinase family.

446462:AMIR RS13710
gene id: 446462:AMIR_RS13710
uniprot id: C6WP03
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

446462:AMIR RS21990
gene id: 446462:AMIR_RS21990
uniprot id: C6WK51
names: Similarity
messages: Belongs to the catalase family.

446462:AMIR RS01840
gene id: 446462:AMIR_RS01840
uniprot id: C6WGL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS07885
gene id: 446462:AMIR_RS07885
uniprot id: C6WBF1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS27120
gene id: 446462:AMIR_RS27120
uniprot id: C6WAA0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

446462:AMIR RS06150
gene id: 446462:AMIR_RS06150
uniprot id: C6WRC7
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

446462:AMIR RS00085
gene id: 446462:AMIR_RS00085
uniprot id: C6WCG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

446462:AMIR RS18565
gene id: 446462:AMIR_RS18565
uniprot id: C6WCY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

446462:AMIR RS30310
gene id: 446462:AMIR_RS30310
uniprot id: C6WHH3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

446462:AMIR RS06650
gene id: 446462:AMIR_RS06650
uniprot id: C6W9B5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

446462:AMIR RS11010
gene id: 446462:AMIR_RS11010
uniprot id: C6WI97
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446462:AMIR RS30475
gene id: 446462:AMIR_RS30475
uniprot id: C6WHK6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

446462:AMIR RS03670
gene id: 446462:AMIR_RS03670
uniprot id: C6WKT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

446462:AMIR RS09260
gene id: 446462:AMIR_RS09260
uniprot id: C6WE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS31730
gene id: 446462:AMIR_RS31730
uniprot id: C6WKF2
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS26385
gene id: 446462:AMIR_RS26385
uniprot id: C6W971
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446462:AMIR RS03040
gene id: 446462:AMIR_RS03040
uniprot id: C6WJD7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

446462:AMIR RS08615
gene id: 446462:AMIR_RS08615
uniprot id: C6WCP5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS00240
gene id: 446462:AMIR_RS00240
uniprot id: C6WCK0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS08935
gene id: 446462:AMIR_RS08935
uniprot id: C6WCW2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446462:AMIR RS33080
gene id: 446462:AMIR_RS33080
uniprot id: C6WNB0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

446462:AMIR RS30430
gene id: 446462:AMIR_RS30430
uniprot id: C6WHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

446462:AMIR RS11290
gene id: 446462:AMIR_RS11290
uniprot id: C6WIE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

446462:AMIR RS30435
gene id: 446462:AMIR_RS30435
uniprot id: C6WHJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

446462:AMIR RS32495
gene id: 446462:AMIR_RS32495
uniprot id: C6WLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

446462:AMIR RS30410
gene id: 446462:AMIR_RS30410
uniprot id: C6WHJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

446462:AMIR RS32180
gene id: 446462:AMIR_RS32180
uniprot id: C6WLQ8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

446462:AMIR RS05410
gene id: 446462:AMIR_RS05410
uniprot id: C6WPX8
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

446462:AMIR RS16060
gene id: 446462:AMIR_RS16060
uniprot id: C6W8M1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

446462:AMIR RS13615
gene id: 446462:AMIR_RS13615
uniprot id: C6WNY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS18015
gene id: 446462:AMIR_RS18015
uniprot id: C6WBT7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS28530
gene id: 446462:AMIR_RS28530
uniprot id: C6WDD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

446462:AMIR RS29320
gene id: 446462:AMIR_RS29320
uniprot id: C6WEV0
names: Similarity
messages: Belongs to the UPF0102 family.

446462:AMIR RS21115
gene id: 446462:AMIR_RS21115
uniprot id: C6WIK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS28395
gene id: 446462:AMIR_RS28395
uniprot id: C6WDA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

446462:AMIR RS21635
gene id: 446462:AMIR_RS21635
uniprot id: C6WIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS09255
gene id: 446462:AMIR_RS09255
uniprot id: C6WE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS32895
gene id: 446462:AMIR_RS32895
uniprot id: C6WN75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

446462:AMIR RS24170
gene id: 446462:AMIR_RS24170
uniprot id: C6WQK0
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS02650
gene id: 446462:AMIR_RS02650
uniprot id: C6WI41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS03900
gene id: 446462:AMIR_RS03900
uniprot id: C6WKY4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

446462:AMIR RS15465
gene id: 446462:AMIR_RS15465
uniprot id: C6W7Y7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06545
gene id: 446462:AMIR_RS06545
uniprot id: C6WRK4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

446462:AMIR RS18645
gene id: 446462:AMIR_RS18645
uniprot id: C6WD04
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS33810
gene id: 446462:AMIR_RS33810
uniprot id: C6WPR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

446462:AMIR RS17565
gene id: 446462:AMIR_RS17565
uniprot id: C6WAU5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

446462:AMIR RS26525
gene id: 446462:AMIR_RS26525
uniprot id: C6W9Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446462:AMIR RS28250
gene id: 446462:AMIR_RS28250
uniprot id: C6WCC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

446462:AMIR RS23595
gene id: 446462:AMIR_RS23595
uniprot id: C6WP72
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS28565
gene id: 446462:AMIR_RS28565
uniprot id: C6WDE0
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32375
gene id: 446462:AMIR_RS32375
uniprot id: C6WLU9
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

446462:AMIR RS14925
gene id: 446462:AMIR_RS14925
uniprot id: C6WRR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS18815
gene id: 446462:AMIR_RS18815
uniprot id: C6WD36
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32720
gene id: 446462:AMIR_RS32720
uniprot id: C6WM19
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

446462:AMIR RS11795
gene id: 446462:AMIR_RS11795
uniprot id: C6WJR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

446462:AMIR RS00720
gene id: 446462:AMIR_RS00720
uniprot id: C6WDW8
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS30705
gene id: 446462:AMIR_RS30705
uniprot id: C6WHQ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS29995
gene id: 446462:AMIR_RS29995
uniprot id: C6WG94
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

446462:AMIR RS08090
gene id: 446462:AMIR_RS08090
uniprot id: C6WBJ2
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS10295
gene id: 446462:AMIR_RS10295
uniprot id: C6WGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS33285
gene id: 446462:AMIR_RS33285
uniprot id: C6WNF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS02345
gene id: 446462:AMIR_RS02345
uniprot id: C6WHY1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

446462:AMIR RS33195
gene id: 446462:AMIR_RS33195
uniprot id: C6WND4
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS25210
gene id: 446462:AMIR_RS25210
uniprot id: C6WS87
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

446462:AMIR RS28910
gene id: 446462:AMIR_RS28910
uniprot id: C6WDK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

446462:AMIR RS04575
gene id: 446462:AMIR_RS04575
uniprot id: C6WMD9
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

446462:AMIR RS34855
gene id: 446462:AMIR_RS34855
uniprot id: C6WSF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

446462:AMIR RS05870
gene id: 446462:AMIR_RS05870
uniprot id: C6WQ68
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446462:AMIR RS04565
gene id: 446462:AMIR_RS04565
uniprot id: C6WMD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

446462:AMIR RS04940
gene id: 446462:AMIR_RS04940
uniprot id: C6WNM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

446462:AMIR RS26095
gene id: 446462:AMIR_RS26095
uniprot id: C6W912
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

446462:AMIR RS34135
gene id: 446462:AMIR_RS34135
uniprot id: C6WQZ0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

446462:AMIR RS07310
gene id: 446462:AMIR_RS07310
uniprot id: C6WAE3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

446462:AMIR RS06765
gene id: 446462:AMIR_RS06765
uniprot id: C6W9D8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

446462:AMIR RS04540
gene id: 446462:AMIR_RS04540
uniprot id: C6WMD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS08560
gene id: 446462:AMIR_RS08560
uniprot id: C6WCN6
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

446462:AMIR RS27995
gene id: 446462:AMIR_RS27995
uniprot id: C6WC75
names: Similarity
messages: Belongs to the CsoR family.

446462:AMIR RS10650
gene id: 446462:AMIR_RS10650
uniprot id: C6WH00
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

446462:AMIR RS31815
gene id: 446462:AMIR_RS31815
uniprot id: C6WKG8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

446462:AMIR RS00685
gene id: 446462:AMIR_RS00685
uniprot id: C6WDW1
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

446462:AMIR RS27625
gene id: 446462:AMIR_RS27625
uniprot id: C6WBA1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

446462:AMIR RS29910
gene id: 446462:AMIR_RS29910
uniprot id: C6WG77
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

446462:AMIR RS19465
gene id: 446462:AMIR_RS19465
uniprot id: C6WEI1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

446462:AMIR RS24135
gene id: 446462:AMIR_RS24135
uniprot id: C6WPI1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

446462:AMIR RS08980
gene id: 446462:AMIR_RS08980
uniprot id: C6WCX1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

446462:AMIR RS31800
gene id: 446462:AMIR_RS31800
uniprot id: C6WKG5
names: Similarity
messages: Belongs to the peptidase M20A family.

446462:AMIR RS22990
gene id: 446462:AMIR_RS22990
uniprot id: C6WMU1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

446462:AMIR RS11815
gene id: 446462:AMIR_RS11815
uniprot id: C6WJS3
names: Similarity
messages: Belongs to the bacterial flagellin family.

446462:AMIR RS31810
gene id: 446462:AMIR_RS31810
uniprot id: C6WKG7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

446462:AMIR RS29510
gene id: 446462:AMIR_RS29510
uniprot id: C6WEY8
names: Similarity
messages: Belongs to the acylphosphatase family.

446462:AMIR RS33370
gene id: 446462:AMIR_RS33370
uniprot id: C6WNG9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS29620
gene id: 446462:AMIR_RS29620
uniprot id: C6WF09
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

446462:AMIR RS09350
gene id: 446462:AMIR_RS09350
uniprot id: C6WE68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

446462:AMIR RS31335
gene id: 446462:AMIR_RS31335
uniprot id: C6WJ47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

446462:AMIR RS03680
gene id: 446462:AMIR_RS03680
uniprot id: C6WKT9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

446462:AMIR RS32730
gene id: 446462:AMIR_RS32730
uniprot id: C6WM21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

446462:AMIR RS32735
gene id: 446462:AMIR_RS32735
uniprot id: C6WM22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

446462:AMIR RS11015
gene id: 446462:AMIR_RS11015
uniprot id: C6WI98
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446462:AMIR RS02765
gene id: 446462:AMIR_RS02765
uniprot id: C6WI64
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS06660
gene id: 446462:AMIR_RS06660
uniprot id: C6W9B7
names: Similarity
messages: Belongs to the CdaR family.

446462:AMIR RS01975
gene id: 446462:AMIR_RS01975
uniprot id: C6WGP1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS33940
gene id: 446462:AMIR_RS33940
uniprot id: C6WPU5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32625
gene id: 446462:AMIR_RS32625
uniprot id: C6WLZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

446462:AMIR RS12100
gene id: 446462:AMIR_RS12100
uniprot id: C6WJY1
names: Similarity
messages: Belongs to the universal stress protein A family.

446462:AMIR RS11900
gene id: 446462:AMIR_RS11900
uniprot id: C6WJU0
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS35115
gene id: 446462:AMIR_RS35115
uniprot id: C6WSK7
names: Similarity
messages: Belongs to the thioredoxin family.

446462:AMIR RS07175
gene id: 446462:AMIR_RS07175
uniprot id: C6WAB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

446462:AMIR RS26555
gene id: 446462:AMIR_RS26555
uniprot id: C6W9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

446462:AMIR RS21745
gene id: 446462:AMIR_RS21745
uniprot id: C6WK04
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS29025
gene id: 446462:AMIR_RS29025
uniprot id: C6WEP2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446462:AMIR RS28520
gene id: 446462:AMIR_RS28520
uniprot id: C6WDD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

446462:AMIR RS05795
gene id: 446462:AMIR_RS05795
uniprot id: C6WQ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

446462:AMIR RS23855
gene id: 446462:AMIR_RS23855
uniprot id: C6WPC5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

446462:AMIR RS28860
gene id: 446462:AMIR_RS28860
uniprot id: C6WDJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

446462:AMIR RS02255
gene id: 446462:AMIR_RS02255
uniprot id: C6WHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS31180
gene id: 446462:AMIR_RS31180
uniprot id: C6WJ17
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446462:AMIR RS02060
gene id: 446462:AMIR_RS02060
uniprot id: C6WGQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS28855
gene id: 446462:AMIR_RS28855
uniprot id: C6WDJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

446462:AMIR RS18755
gene id: 446462:AMIR_RS18755
uniprot id: C6WD24
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

446462:AMIR RS05800
gene id: 446462:AMIR_RS05800
uniprot id: C6WQ53
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

446462:AMIR RS13475
gene id: 446462:AMIR_RS13475
uniprot id: C6WNW0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446462:AMIR RS01845
gene id: 446462:AMIR_RS01845
uniprot id: C6WGL6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

446462:AMIR RS01070
gene id: 446462:AMIR_RS01070
uniprot id: C6WF47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS25875
gene id: 446462:AMIR_RS25875
uniprot id: C6W8J2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

446462:AMIR RS31355
gene id: 446462:AMIR_RS31355
uniprot id: C6WJ51
names: Similarity
messages: Belongs to the PGI/PMI family.

446462:AMIR RS25085
gene id: 446462:AMIR_RS25085
uniprot id: C6WS60
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS31655
gene id: 446462:AMIR_RS31655
uniprot id: C6WKD7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

446462:AMIR RS15450
gene id: 446462:AMIR_RS15450
uniprot id: C6W7Y4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS09985
gene id: 446462:AMIR_RS09985
uniprot id: C6WFK7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS00440
gene id: 446462:AMIR_RS00440
uniprot id: C6WDR7
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

446462:AMIR RS06790
gene id: 446462:AMIR_RS06790
uniprot id: C6W9E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

446462:AMIR RS32975
gene id: 446462:AMIR_RS32975
uniprot id: C6WN88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

446462:AMIR RS01135
gene id: 446462:AMIR_RS01135
uniprot id: C6WF60
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32755
gene id: 446462:AMIR_RS32755
uniprot id: C6WM26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

446462:AMIR RS29750
gene id: 446462:AMIR_RS29750
uniprot id: C6WG47
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

446462:AMIR RS19230
gene id: 446462:AMIR_RS19230
uniprot id: C6WED6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

446462:AMIR RS27030
gene id: 446462:AMIR_RS27030
uniprot id: C6WA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

446462:AMIR RS25805
gene id: 446462:AMIR_RS25805
uniprot id: C6W8H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

446462:AMIR RS16655
gene id: 446462:AMIR_RS16655
uniprot id: C6W9M2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS04305
gene id: 446462:AMIR_RS04305
uniprot id: C6WM87
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

446462:AMIR RS35170
gene id: 446462:AMIR_RS35170
uniprot id: C6WSL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

446462:AMIR RS09765
gene id: 446462:AMIR_RS09765
uniprot id: C6WFG3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

446462:AMIR RS30665
gene id: 446462:AMIR_RS30665
uniprot id: C6WHP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS23810
gene id: 446462:AMIR_RS23810
uniprot id: C6WPB6
names: Similarity
messages: Belongs to the type IB topoisomerase family.

446462:AMIR RS32890
gene id: 446462:AMIR_RS32890
uniprot id: C6WN74
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

446462:AMIR RS28185
gene id: 446462:AMIR_RS28185
uniprot id: C6WCB3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

446462:AMIR RS03550
gene id: 446462:AMIR_RS03550
uniprot id: C6WKR3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

446462:AMIR RS32490
gene id: 446462:AMIR_RS32490
uniprot id: C6WLX2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS34120
gene id: 446462:AMIR_RS34120
uniprot id: C6WQY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS06820
gene id: 446462:AMIR_RS06820
uniprot id: C6W9E9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

446462:AMIR RS12135
gene id: 446462:AMIR_RS12135
uniprot id: C6WL10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS10415
gene id: 446462:AMIR_RS10415
uniprot id: C6WGV4
names: Similarity
messages: Belongs to the glutamine synthetase family.

446462:AMIR RS20825
gene id: 446462:AMIR_RS20825
uniprot id: C6WHB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446462:AMIR RS12885
gene id: 446462:AMIR_RS12885
uniprot id: C6WMI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

446462:AMIR RS20935
gene id: 446462:AMIR_RS20935
uniprot id: C6WHE0
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

446462:AMIR RS05895
gene id: 446462:AMIR_RS05895
uniprot id: C6WQ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS18970
gene id: 446462:AMIR_RS18970
uniprot id: C6WD65
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS34505
gene id: 446462:AMIR_RS34505
uniprot id: C6WR65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS01820
gene id: 446462:AMIR_RS01820
uniprot id: C6WGL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

446462:AMIR RS08365
gene id: 446462:AMIR_RS08365
uniprot id: C6WBP6
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

446462:AMIR RS10045
gene id: 446462:AMIR_RS10045
uniprot id: C6WFL9
names: Cofactor
messages: Can also use Mn(2+) ion.

446462:AMIR RS11680
gene id: 446462:AMIR_RS11680
uniprot id: C6WJP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

446462:AMIR RS34420
gene id: 446462:AMIR_RS34420
uniprot id: C6WR49
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

446462:AMIR RS10545
gene id: 446462:AMIR_RS10545
uniprot id: C6WGY0
names: Similarity
messages: Belongs to the CdaR family.

446462:AMIR RS07315
gene id: 446462:AMIR_RS07315
uniprot id: C6WAE4
names: Similarity
messages: Belongs to the peptidase S15 family.

446462:AMIR RS02245
gene id: 446462:AMIR_RS02245
uniprot id: C6WHW1
names: Similarity
messages: Belongs to the CutC family.

446462:AMIR RS23240
gene id: 446462:AMIR_RS23240
uniprot id: C6WMY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

446462:AMIR RS22135
gene id: 446462:AMIR_RS22135
uniprot id: C6WK78
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS28885
gene id: 446462:AMIR_RS28885
uniprot id: C6WDK3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS29815
gene id: 446462:AMIR_RS29815
uniprot id: C6WG57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS30070
gene id: 446462:AMIR_RS30070
uniprot id: C6WGB0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446462:AMIR RS13235
gene id: 446462:AMIR_RS13235
uniprot id: C6WMQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

446462:AMIR RS27500
gene id: 446462:AMIR_RS27500
uniprot id: C6WB76
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

446462:AMIR RS07170
gene id: 446462:AMIR_RS07170
uniprot id: C6WAB5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

446462:AMIR RS30680
gene id: 446462:AMIR_RS30680
uniprot id: C6WHP5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446462:AMIR RS02665
gene id: 446462:AMIR_RS02665
uniprot id: C6WI44
names: Similarity
messages: Belongs to the citrate synthase family.

446462:AMIR RS25290
gene id: 446462:AMIR_RS25290
uniprot id: C6W878
names: Similarity
messages: Belongs to the peptidase S66 family.

446462:AMIR RS20895
gene id: 446462:AMIR_RS20895
uniprot id: C6WHD1
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS04965
gene id: 446462:AMIR_RS04965
uniprot id: C6WNM8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

446462:AMIR RS10460
gene id: 446462:AMIR_RS10460
uniprot id: C6WGW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446462:AMIR RS31365
gene id: 446462:AMIR_RS31365
uniprot id: C6WJ53
names: Similarity
messages: Belongs to the phosphohexose mutase family.

446462:AMIR RS23125
gene id: 446462:AMIR_RS23125
uniprot id: C6WMW6
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32765
gene id: 446462:AMIR_RS32765
uniprot id: C6WM28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

446462:AMIR RS41185
gene id: 446462:AMIR_RS41185
uniprot id: C6WHC0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446462:AMIR RS25580
gene id: 446462:AMIR_RS25580
uniprot id: C6W8D3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS24405
gene id: 446462:AMIR_RS24405
uniprot id: C6WQP9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

446462:AMIR RS01595
gene id: 446462:AMIR_RS01595
uniprot id: C6WGG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

446462:AMIR RS02035
gene id: 446462:AMIR_RS02035
uniprot id: C6WGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS09295
gene id: 446462:AMIR_RS09295
uniprot id: C6WE57
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS30395
gene id: 446462:AMIR_RS30395
uniprot id: C6WHJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS39260
gene id: 446462:AMIR_RS39260
uniprot id: C6W9X3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

446462:AMIR RS25945
gene id: 446462:AMIR_RS25945
uniprot id: C6W8Y2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS08625
gene id: 446462:AMIR_RS08625
uniprot id: C6WCP8
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS28055
gene id: 446462:AMIR_RS28055
uniprot id: C6WC87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

446462:AMIR RS30930
gene id: 446462:AMIR_RS30930
uniprot id: C6WIW8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

446462:AMIR RS15700
gene id: 446462:AMIR_RS15700
uniprot id: C6W833
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS20425
gene id: 446462:AMIR_RS20425
uniprot id: C6WG19
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS21150
gene id: 446462:AMIR_RS21150
uniprot id: C6WIL2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS25770
gene id: 446462:AMIR_RS25770
uniprot id: C6W8H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446462:AMIR RS15490
gene id: 446462:AMIR_RS15490
uniprot id: C6W7Z2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446462:AMIR RS32560
gene id: 446462:AMIR_RS32560
uniprot id: C6WLY6
names: Similarity
messages: Belongs to the EccD/Snm4 family.

446462:AMIR RS31555
gene id: 446462:AMIR_RS31555
uniprot id: C6WKB8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS08405
gene id: 446462:AMIR_RS08405
uniprot id: C6WCK5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS07795
gene id: 446462:AMIR_RS07795
uniprot id: C6WBD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS34995
gene id: 446462:AMIR_RS34995
uniprot id: C6WSI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

446462:AMIR RS05215
gene id: 446462:AMIR_RS05215
uniprot id: C6WNS6
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS10945
gene id: 446462:AMIR_RS10945
uniprot id: C6WI84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS31775
gene id: 446462:AMIR_RS31775
uniprot id: C6WKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

446462:AMIR RS34165
gene id: 446462:AMIR_RS34165
uniprot id: C6WQZ6
names: Similarity
messages: Belongs to the threonine aldolase family.

446462:AMIR RS17825
gene id: 446462:AMIR_RS17825
uniprot id: C6WAZ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS28030
gene id: 446462:AMIR_RS28030
uniprot id: C6WC82
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

446462:AMIR RS12255
gene id: 446462:AMIR_RS12255
uniprot id: C6WL35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

446462:AMIR RS23960
gene id: 446462:AMIR_RS23960
uniprot id: C6WPE6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

446462:AMIR RS04470
gene id: 446462:AMIR_RS04470
uniprot id: C6WMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

446462:AMIR RS08495
gene id: 446462:AMIR_RS08495
uniprot id: C6WCM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

446462:AMIR RS33455
gene id: 446462:AMIR_RS33455
uniprot id: C6WPJ9
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

446462:AMIR RS30710
gene id: 446462:AMIR_RS30710
uniprot id: C6WHQ2
names: Similarity
messages: Belongs to the YciI family.

446462:AMIR RS28795
gene id: 446462:AMIR_RS28795
uniprot id: C6WDI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

446462:AMIR RS09995
gene id: 446462:AMIR_RS09995
uniprot id: C6WFK9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS07695
gene id: 446462:AMIR_RS07695
uniprot id: C6WAL6
names: Similarity
messages: Belongs to the mycobacterial PPE family.

446462:AMIR RS04090
gene id: 446462:AMIR_RS04090
uniprot id: C6WM43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

446462:AMIR RS26055
gene id: 446462:AMIR_RS26055
uniprot id: C6W904
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

446462:AMIR RS04995
gene id: 446462:AMIR_RS04995
uniprot id: C6WNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

446462:AMIR RS13595
gene id: 446462:AMIR_RS13595
uniprot id: C6WNY4
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS01880
gene id: 446462:AMIR_RS01880
uniprot id: C6WGM3
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

446462:AMIR RS15340
gene id: 446462:AMIR_RS15340
uniprot id: C6W7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS22365
gene id: 446462:AMIR_RS22365
uniprot id: C6WLE4
names: Similarity
messages: Belongs to the thioesterase family.

446462:AMIR RS33685
gene id: 446462:AMIR_RS33685
uniprot id: C6WPP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

446462:AMIR RS01065
gene id: 446462:AMIR_RS01065
uniprot id: C6WF46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS26305
gene id: 446462:AMIR_RS26305
uniprot id: C6W955
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS09300
gene id: 446462:AMIR_RS09300
uniprot id: C6WE58
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS25340
gene id: 446462:AMIR_RS25340
uniprot id: C6W889
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446462:AMIR RS08925
gene id: 446462:AMIR_RS08925
uniprot id: C6WCW0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446462:AMIR RS03465
gene id: 446462:AMIR_RS03465
uniprot id: C6WKP6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

446462:AMIR RS20710
gene id: 446462:AMIR_RS20710
uniprot id: C6WH94
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

446462:AMIR RS05635
gene id: 446462:AMIR_RS05635
uniprot id: C6WQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS33515
gene id: 446462:AMIR_RS33515
uniprot id: C6WPL1
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

446462:AMIR RS03415
gene id: 446462:AMIR_RS03415
uniprot id: C6WJK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS07580
gene id: 446462:AMIR_RS07580
uniprot id: C6WAJ5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

446462:AMIR RS08810
gene id: 446462:AMIR_RS08810
uniprot id: C6WCT6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446462:AMIR RS02260
gene id: 446462:AMIR_RS02260
uniprot id: C6WHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS32045
gene id: 446462:AMIR_RS32045
uniprot id: C6WKL5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

446462:AMIR RS35060
gene id: 446462:AMIR_RS35060
uniprot id: C6WSJ7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

446462:AMIR RS18470
gene id: 446462:AMIR_RS18470
uniprot id: C6WC22
names: Subcellular Location Annotation
messages: Cytoplasm

446462:AMIR RS23045
gene id: 446462:AMIR_RS23045
uniprot id: C6WMV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS34020
gene id: 446462:AMIR_RS34020
uniprot id: C6WQW9
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS13955
gene id: 446462:AMIR_RS13955
uniprot id: C6WP53
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS23350
gene id: 446462:AMIR_RS23350
uniprot id: C6WN13
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS34620
gene id: 446462:AMIR_RS34620
uniprot id: C6WSB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS10580
gene id: 446462:AMIR_RS10580
uniprot id: C6WGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

446462:AMIR RS23980
gene id: 446462:AMIR_RS23980
uniprot id: C6WPF0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS30110
gene id: 446462:AMIR_RS30110
uniprot id: C6WGB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

446462:AMIR RS30970
gene id: 446462:AMIR_RS30970
uniprot id: C6WIX6
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

446462:AMIR RS36035
gene id: 446462:AMIR_RS36035
uniprot id: C6WLH0
names: Similarity
messages: Belongs to the mycobacterial PPE family.

446462:AMIR RS01140
gene id: 446462:AMIR_RS01140
uniprot id: C6WF61
names: Similarity
messages: Belongs to the catalase family.

446462:AMIR RS24385
gene id: 446462:AMIR_RS24385
uniprot id: C6WQP5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS25705
gene id: 446462:AMIR_RS25705
uniprot id: C6W8F7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS31215
gene id: 446462:AMIR_RS31215
uniprot id: C6WJ24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446462:AMIR RS07100
gene id: 446462:AMIR_RS07100
uniprot id: C6W9K5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS30630
gene id: 446462:AMIR_RS30630
uniprot id: C6WHN6
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

446462:AMIR RS08480
gene id: 446462:AMIR_RS08480
uniprot id: C6WCM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

446462:AMIR RS29190
gene id: 446462:AMIR_RS29190
uniprot id: C6WES5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

446462:AMIR RS14930
gene id: 446462:AMIR_RS14930
uniprot id: C6WRR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

446462:AMIR RS07115
gene id: 446462:AMIR_RS07115
uniprot id: C6WAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

446462:AMIR RS33610
gene id: 446462:AMIR_RS33610
uniprot id: C6WPN1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS09965
gene id: 446462:AMIR_RS09965
uniprot id: C6WFK3
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

446462:AMIR RS21395
gene id: 446462:AMIR_RS21395
uniprot id: C6WIQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

446462:AMIR RS03865
gene id: 446462:AMIR_RS03865
uniprot id: C6WKX7
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446462:AMIR RS11170
gene id: 446462:AMIR_RS11170
uniprot id: C6WIC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

446462:AMIR RS34210
gene id: 446462:AMIR_RS34210
uniprot id: C6WR05
names: Similarity
messages: Belongs to the GARS family.

446462:AMIR RS05425
gene id: 446462:AMIR_RS05425
uniprot id: C6WPY1
names: Cofactor
messages: Binds 1 FAD per subunit.

446462:AMIR RS32880
gene id: 446462:AMIR_RS32880
uniprot id: C6WN72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

446462:AMIR RS31265
gene id: 446462:AMIR_RS31265
uniprot id: C6WJ34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

446462:AMIR RS15120
gene id: 446462:AMIR_RS15120
uniprot id: C6WRV1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

446462:AMIR RS31980
gene id: 446462:AMIR_RS31980
uniprot id: C6WKK2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS31340
gene id: 446462:AMIR_RS31340
uniprot id: C6WJ48
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS14260
gene id: 446462:AMIR_RS14260
uniprot id: C6WQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS16940
gene id: 446462:AMIR_RS16940
uniprot id: C6W9S5
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS34145
gene id: 446462:AMIR_RS34145
uniprot id: C6WQZ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS09760
gene id: 446462:AMIR_RS09760
uniprot id: C6WFG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

446462:AMIR RS08115
gene id: 446462:AMIR_RS08115
uniprot id: C6WBJ7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

446462:AMIR RS26585
gene id: 446462:AMIR_RS26585
uniprot id: C6W9Z4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446462:AMIR RS32085
gene id: 446462:AMIR_RS32085
uniprot id: C6WKM3
names: Similarity
messages: Belongs to the HepT RNase toxin family.

446462:AMIR RS34235
gene id: 446462:AMIR_RS34235
uniprot id: C6WR10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

446462:AMIR RS24720
gene id: 446462:AMIR_RS24720
uniprot id: C6WQW3
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS17710
gene id: 446462:AMIR_RS17710
uniprot id: C6WAX3
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS31060
gene id: 446462:AMIR_RS31060
uniprot id: C6WIZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

446462:AMIR RS24475
gene id: 446462:AMIR_RS24475
uniprot id: C6WQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS28915
gene id: 446462:AMIR_RS28915
uniprot id: C6WDK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

446462:AMIR RS30525
gene id: 446462:AMIR_RS30525
uniprot id: C6WHL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

446462:AMIR RS06290
gene id: 446462:AMIR_RS06290
uniprot id: C6WRF5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

446462:AMIR RS07465
gene id: 446462:AMIR_RS07465
uniprot id: C6WAH2
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

446462:AMIR RS25505
gene id: 446462:AMIR_RS25505
uniprot id: C6W8B8
names: Similarity
messages: Belongs to the lycopene cyclase family.

446462:AMIR RS20920
gene id: 446462:AMIR_RS20920
uniprot id: C6WHD7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

446462:AMIR RS10180
gene id: 446462:AMIR_RS10180
uniprot id: C6WFP1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS07635
gene id: 446462:AMIR_RS07635
uniprot id: C6WAK6
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS12350
gene id: 446462:AMIR_RS12350
uniprot id: C6WL55
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS28180
gene id: 446462:AMIR_RS28180
uniprot id: C6WCB2
names: Similarity
messages: Belongs to the group II decarboxylase family.

446462:AMIR RS18285
gene id: 446462:AMIR_RS18285
uniprot id: C6WBY6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

446462:AMIR RS22105
gene id: 446462:AMIR_RS22105
uniprot id: C6WK72
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

446462:AMIR RS32650
gene id: 446462:AMIR_RS32650
uniprot id: C6WM05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446462:AMIR RS17765
gene id: 446462:AMIR_RS17765
uniprot id: C6WAY5
names: Similarity
messages: Belongs to the peptidase S8 family.

446462:AMIR RS28695
gene id: 446462:AMIR_RS28695
uniprot id: C6WDG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

446462:AMIR RS01935
gene id: 446462:AMIR_RS01935
uniprot id: C6WGN3
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

446462:AMIR RS29690
gene id: 446462:AMIR_RS29690
uniprot id: C6WG34
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS14555
gene id: 446462:AMIR_RS14555
uniprot id: C6WQH8
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

446462:AMIR RS20955
gene id: 446462:AMIR_RS20955
uniprot id: C6WHE4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

446462:AMIR RS12770
gene id: 446462:AMIR_RS12770
uniprot id: C6WMG1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS08735
gene id: 446462:AMIR_RS08735
uniprot id: C6WCS0
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS24070
gene id: 446462:AMIR_RS24070
uniprot id: C6WPG7
names: Similarity
messages: Belongs to the peptidase S9A family.

446462:AMIR RS30875
gene id: 446462:AMIR_RS30875
uniprot id: C6WHT4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

446462:AMIR RS06535
gene id: 446462:AMIR_RS06535
uniprot id: C6WRK2
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS05785
gene id: 446462:AMIR_RS05785
uniprot id: C6WQ50
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS11520
gene id: 446462:AMIR_RS11520
uniprot id: C6WJL3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446462:AMIR RS26825
gene id: 446462:AMIR_RS26825
uniprot id: C6WA43
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS13155
gene id: 446462:AMIR_RS13155
uniprot id: C6WMN9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS13785
gene id: 446462:AMIR_RS13785
uniprot id: C6WP18
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS04445
gene id: 446462:AMIR_RS04445
uniprot id: C6WMB6
names: Similarity
messages: Belongs to the peptidase C40 family.

446462:AMIR RS32905
gene id: 446462:AMIR_RS32905
uniprot id: C6WN76
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS31830
gene id: 446462:AMIR_RS31830
uniprot id: C6WKH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

446462:AMIR RS06360
gene id: 446462:AMIR_RS06360
uniprot id: C6WRG9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS03875
gene id: 446462:AMIR_RS03875
uniprot id: C6WKX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS00545
gene id: 446462:AMIR_RS00545
uniprot id: C6WDT6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

446462:AMIR RS00965
gene id: 446462:AMIR_RS00965
uniprot id: C6WF30
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

446462:AMIR RS00460
gene id: 446462:AMIR_RS00460
uniprot id: C6WDS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

446462:AMIR RS03765
gene id: 446462:AMIR_RS03765
uniprot id: C6WKV6
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS24490
gene id: 446462:AMIR_RS24490
uniprot id: C6WQR7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06920
gene id: 446462:AMIR_RS06920
uniprot id: C6W9G9
names: Similarity
messages: Belongs to the peptidase C40 family.

446462:AMIR RS34445
gene id: 446462:AMIR_RS34445
uniprot id: C6WR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS07215
gene id: 446462:AMIR_RS07215
uniprot id: C6WAC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446462:AMIR RS05140
gene id: 446462:AMIR_RS05140
uniprot id: C6WNR2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

446462:AMIR RS32270
gene id: 446462:AMIR_RS32270
uniprot id: C6WLS8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

446462:AMIR RS02550
gene id: 446462:AMIR_RS02550
uniprot id: C6WI22
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

446462:AMIR RS08520
gene id: 446462:AMIR_RS08520
uniprot id: C6WCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

446462:AMIR RS04660
gene id: 446462:AMIR_RS04660
uniprot id: C6WMF5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: Nucleus
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446462:AMIR RS06725
gene id: 446462:AMIR_RS06725
uniprot id: C6W9D0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

446462:AMIR RS11710
gene id: 446462:AMIR_RS11710
uniprot id: C6WJQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

446462:AMIR RS11675
gene id: 446462:AMIR_RS11675
uniprot id: C6WJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

446462:AMIR RS16785
gene id: 446462:AMIR_RS16785
uniprot id: C6W9P4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS03410
gene id: 446462:AMIR_RS03410
uniprot id: C6WJK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

446462:AMIR RS21975
gene id: 446462:AMIR_RS21975
uniprot id: C6WK48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

446462:AMIR RS10220
gene id: 446462:AMIR_RS10220
uniprot id: C6WFP8
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS18290
gene id: 446462:AMIR_RS18290
uniprot id: C6WBY7
names: Similarity
messages: Belongs to the NodU/CmcH family.

446462:AMIR RS15375
gene id: 446462:AMIR_RS15375
uniprot id: C6W7X0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS25515
gene id: 446462:AMIR_RS25515
uniprot id: C6W8C0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

446462:AMIR RS13230
gene id: 446462:AMIR_RS13230
uniprot id: C6WMQ4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

446462:AMIR RS23815
gene id: 446462:AMIR_RS23815
uniprot id: C6WPB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

446462:AMIR RS22305
gene id: 446462:AMIR_RS22305
uniprot id: C6WLD2
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS05855
gene id: 446462:AMIR_RS05855
uniprot id: C6WQ65
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

446462:AMIR RS29555
gene id: 446462:AMIR_RS29555
uniprot id: C6WEZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

446462:AMIR RS29175
gene id: 446462:AMIR_RS29175
uniprot id: C6WES2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

446462:AMIR RS30955
gene id: 446462:AMIR_RS30955
uniprot id: C6WIX3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

446462:AMIR RS35875
gene id: 446462:AMIR_RS35875
uniprot id: C6WBS7
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

446462:AMIR RS03955
gene id: 446462:AMIR_RS03955
uniprot id: C6WKZ6
names: Similarity
messages: Belongs to the peptidase M17 family.

446462:AMIR RS27025
gene id: 446462:AMIR_RS27025
uniprot id: C6WA81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

446462:AMIR RS32470
gene id: 446462:AMIR_RS32470
uniprot id: C6WLW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

446462:AMIR RS05990
gene id: 446462:AMIR_RS05990
uniprot id: C6WR96
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

446462:AMIR RS24905
gene id: 446462:AMIR_RS24905
uniprot id: C6WS21
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

446462:AMIR RS19655
gene id: 446462:AMIR_RS19655
uniprot id: C6WEL3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS32615
gene id: 446462:AMIR_RS32615
uniprot id: C6WLZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

446462:AMIR RS25780
gene id: 446462:AMIR_RS25780
uniprot id: C6W8H2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

446462:AMIR RS32080
gene id: 446462:AMIR_RS32080
uniprot id: C6WKM2
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

446462:AMIR RS30325
gene id: 446462:AMIR_RS30325
uniprot id: C6WHH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

446462:AMIR RS19745
gene id: 446462:AMIR_RS19745
uniprot id: C6WEN1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

446462:AMIR RS11760
gene id: 446462:AMIR_RS11760
uniprot id: C6WJR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

446462:AMIR RS02590
gene id: 446462:AMIR_RS02590
uniprot id: C6WI30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS17785
gene id: 446462:AMIR_RS17785
uniprot id: C6WAY9
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

446462:AMIR RS13990
gene id: 446462:AMIR_RS13990
uniprot id: C6WP60
names: Similarity
messages: Belongs to the asp23 family.

446462:AMIR RS25455
gene id: 446462:AMIR_RS25455
uniprot id: C6W8B1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS17070
gene id: 446462:AMIR_RS17070
uniprot id: C6W9V1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06575
gene id: 446462:AMIR_RS06575
uniprot id: C6W999
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

446462:AMIR RS05670
gene id: 446462:AMIR_RS05670
uniprot id: C6WQ29
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

446462:AMIR RS12935
gene id: 446462:AMIR_RS12935
uniprot id: C6WMJ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

446462:AMIR RS31725
gene id: 446462:AMIR_RS31725
uniprot id: C6WKF1
names: Similarity
messages: Belongs to the mycobacterial PPE family.

446462:AMIR RS02540
gene id: 446462:AMIR_RS02540
uniprot id: C6WI20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

446462:AMIR RS28865
gene id: 446462:AMIR_RS28865
uniprot id: C6WDJ9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

446462:AMIR RS08535
gene id: 446462:AMIR_RS08535
uniprot id: C6WCN1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

446462:AMIR RS10040
gene id: 446462:AMIR_RS10040
uniprot id: C6WFL8
names: Similarity
messages: Belongs to the malate synthase family.

446462:AMIR RS26020
gene id: 446462:AMIR_RS26020
uniprot id: C6W8Z7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

446462:AMIR RS09660
gene id: 446462:AMIR_RS09660
uniprot id: C6WFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS15720
gene id: 446462:AMIR_RS15720
uniprot id: C6W837
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS01095
gene id: 446462:AMIR_RS01095
uniprot id: C6WF52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

446462:AMIR RS32675
gene id: 446462:AMIR_RS32675
uniprot id: C6WM10
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

446462:AMIR RS13495
gene id: 446462:AMIR_RS13495
uniprot id: C6WNW4
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS03745
gene id: 446462:AMIR_RS03745
uniprot id: C6WKV2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

446462:AMIR RS27640
gene id: 446462:AMIR_RS27640
uniprot id: C6WBA4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

446462:AMIR RS33780
gene id: 446462:AMIR_RS33780
uniprot id: C6WPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

446462:AMIR RS24085
gene id: 446462:AMIR_RS24085
uniprot id: C6WPH0
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS03195
gene id: 446462:AMIR_RS03195
uniprot id: C6WJG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

446462:AMIR RS23520
gene id: 446462:AMIR_RS23520
uniprot id: C6WN47
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

446462:AMIR RS33800
gene id: 446462:AMIR_RS33800
uniprot id: C6WPR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

446462:AMIR RS01490
gene id: 446462:AMIR_RS01490
uniprot id: C6WFD0
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

446462:AMIR RS30670
gene id: 446462:AMIR_RS30670
uniprot id: C6WHP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS25125
gene id: 446462:AMIR_RS25125
uniprot id: C6WS68
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

446462:AMIR RS07645
gene id: 446462:AMIR_RS07645
uniprot id: C6WAK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

446462:AMIR RS03305
gene id: 446462:AMIR_RS03305
uniprot id: C6WJI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS31200
gene id: 446462:AMIR_RS31200
uniprot id: C6WJ21
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

446462:AMIR RS20735
gene id: 446462:AMIR_RS20735
uniprot id: C6WH99
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

446462:AMIR RS18400
gene id: 446462:AMIR_RS18400
uniprot id: C6WC08
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS29160
gene id: 446462:AMIR_RS29160
uniprot id: C6WER9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

446462:AMIR RS29680
gene id: 446462:AMIR_RS29680
uniprot id: C6WG32
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

446462:AMIR RS25955
gene id: 446462:AMIR_RS25955
uniprot id: C6W8Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

446462:AMIR RS15505
gene id: 446462:AMIR_RS15505
uniprot id: C6W7Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

446462:AMIR RS06370
gene id: 446462:AMIR_RS06370
uniprot id: C6WRH1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

446462:AMIR RS08010
gene id: 446462:AMIR_RS08010
uniprot id: C6WBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

446462:AMIR RS04195
gene id: 446462:AMIR_RS04195
uniprot id: C6WM65
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

446462:AMIR RS30515
gene id: 446462:AMIR_RS30515
uniprot id: C6WHL3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

446462:AMIR RS33630
gene id: 446462:AMIR_RS33630
uniprot id: C6WPN5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS10380
gene id: 446462:AMIR_RS10380
uniprot id: C6WGU7
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

446462:AMIR RS19210
gene id: 446462:AMIR_RS19210
uniprot id: C6WED2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

446462:AMIR RS17690
gene id: 446462:AMIR_RS17690
uniprot id: C6WAW9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS32455
gene id: 446462:AMIR_RS32455
uniprot id: C6WLW5
names: Similarity
messages: Belongs to the thioredoxin family.

446462:AMIR RS25430
gene id: 446462:AMIR_RS25430
uniprot id: C6W8A6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

446462:AMIR RS04755
gene id: 446462:AMIR_RS04755
uniprot id: C6WNI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

446462:AMIR RS27225
gene id: 446462:AMIR_RS27225
uniprot id: C6WB19
names: Similarity
messages: Belongs to the AHA1 family.

446462:AMIR RS30750
gene id: 446462:AMIR_RS30750
uniprot id: C6WHR0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446462:AMIR RS25775
gene id: 446462:AMIR_RS25775
uniprot id: C6W8H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

446462:AMIR RS16400
gene id: 446462:AMIR_RS16400
uniprot id: C6W8U0
names: Similarity
messages: Belongs to the NodU/CmcH family.

446462:AMIR RS05340
gene id: 446462:AMIR_RS05340
uniprot id: C6WPW2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

446462:AMIR RS23865
gene id: 446462:AMIR_RS23865
uniprot id: C6WPC7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS00845
gene id: 446462:AMIR_RS00845
uniprot id: C6WDZ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

446462:AMIR RS04395
gene id: 446462:AMIR_RS04395
uniprot id: C6WMA6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

446462:AMIR RS28600
gene id: 446462:AMIR_RS28600
uniprot id: C6WDE7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

446462:AMIR RS10170
gene id: 446462:AMIR_RS10170
uniprot id: C6WFN9
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS28485
gene id: 446462:AMIR_RS28485
uniprot id: C6WDC5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

446462:AMIR RS31015
gene id: 446462:AMIR_RS31015
uniprot id: C6WIY5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

446462:AMIR RS34160
gene id: 446462:AMIR_RS34160
uniprot id: C6WQZ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

446462:AMIR RS29180
gene id: 446462:AMIR_RS29180
uniprot id: C6WES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

446462:AMIR RS14110
gene id: 446462:AMIR_RS14110
uniprot id: C6WQ97
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

446462:AMIR RS28415
gene id: 446462:AMIR_RS28415
uniprot id: C6WDB1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS06265
gene id: 446462:AMIR_RS06265
uniprot id: C6WRF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

446462:AMIR RS23605
gene id: 446462:AMIR_RS23605
uniprot id: C6WP74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

446462:AMIR RS28720
gene id: 446462:AMIR_RS28720
uniprot id: C6WDH2
names: Similarity
messages: Belongs to the PspA/IM30 family.

446462:AMIR RS29645
gene id: 446462:AMIR_RS29645
uniprot id: C6WF14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

446462:AMIR RS29760
gene id: 446462:AMIR_RS29760
uniprot id: C6WG49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

446462:AMIR RS25905
gene id: 446462:AMIR_RS25905
uniprot id: C6W8J8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

446462:AMIR RS25330
gene id: 446462:AMIR_RS25330
uniprot id: C6W887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

446462:AMIR RS22310
gene id: 446462:AMIR_RS22310
uniprot id: C6WLD3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

446462:AMIR RS16365
gene id: 446462:AMIR_RS16365
uniprot id: C6W8T3
names: Similarity
messages: Belongs to the cytochrome P450 family.

446462:AMIR RS24295
gene id: 446462:AMIR_RS24295
uniprot id: C6WQM7
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

446462:AMIR RS19625
gene id: 446462:AMIR_RS19625
uniprot id: C6WEK7
names: Similarity
messages: Belongs to the AHA1 family.

446462:AMIR RS07600
gene id: 446462:AMIR_RS07600
uniprot id: C6WAJ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

446462:AMIR RS19940
gene id: 446462:AMIR_RS19940
uniprot id: C6WFT1
names: Similarity
messages: Belongs to the thioesterase family.

446462:AMIR RS27035
gene id: 446462:AMIR_RS27035
uniprot id: C6WA83
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

446462:AMIR RS24495
gene id: 446462:AMIR_RS24495
uniprot id: C6WQR8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

446462:AMIR RS05315
gene id: 446462:AMIR_RS05315
uniprot id: C6WPV7
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS29720
gene id: 446462:AMIR_RS29720
uniprot id: C6WG41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

446462:AMIR RS31610
gene id: 446462:AMIR_RS31610
uniprot id: C6WKC9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

446462:AMIR RS03620
gene id: 446462:AMIR_RS03620
uniprot id: C6WKS7
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

446462:AMIR RS32420
gene id: 446462:AMIR_RS32420
uniprot id: C6WLV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

446462:AMIR RS25910
gene id: 446462:AMIR_RS25910
uniprot id: C6W8J9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

446462:AMIR RS15900
gene id: 446462:AMIR_RS15900
uniprot id: C6W872
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

446462:AMIR RS06095
gene id: 446462:AMIR_RS06095
uniprot id: C6WRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

446462:AMIR RS15525
gene id: 446462:AMIR_RS15525
uniprot id: C6W7Z9
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

446462:AMIR RS05085
gene id: 446462:AMIR_RS05085
uniprot id: C6WNQ1
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS19160
gene id: 446462:AMIR_RS19160
uniprot id: C6WDA3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

446462:AMIR RS21200
gene id: 446462:AMIR_RS21200
uniprot id: C6WIL8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

446462:AMIR RS01780
gene id: 446462:AMIR_RS01780
uniprot id: C6WGK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

446462:AMIR RS10235
gene id: 446462:AMIR_RS10235
uniprot id: C6WFQ1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

446462:AMIR RS18320
gene id: 446462:AMIR_RS18320
uniprot id: C6WBZ3
names: Similarity
messages: Belongs to the asparagine synthetase family.

446462:AMIR RS05020
gene id: 446462:AMIR_RS05020
uniprot id: C6WNN8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

446462:AMIR RS17365
gene id: 446462:AMIR_RS17365
uniprot id: C6WAQ7
names: Similarity
messages: Belongs to the EspG family.

446462:AMIR RS33380
gene id: 446462:AMIR_RS33380
uniprot id: C6WPI4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

446462:AMIR RS15445
gene id: 446462:AMIR_RS15445
uniprot id: C6W7Y3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

446462:AMIR RS01560
gene id: 446462:AMIR_RS01560
uniprot id: C6WGG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

446462:AMIR RS01420
gene id: 446462:AMIR_RS01420
uniprot id: C6WFB4
names: Subcellular Location Annotation
messages: Membrane

446462:AMIR RS33345
gene id: 446462:AMIR_RS33345
uniprot id: C6WNG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

446462:AMIR RS04530
gene id: 446462:AMIR_RS04530
uniprot id: C6WMD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

446462:AMIR RS08940
gene id: 446462:AMIR_RS08940
uniprot id: C6WCW3
names: Similarity
messages: Belongs to the CobH/CbiC family.

446462:AMIR RS31690
gene id: 446462:AMIR_RS31690
uniprot id: C6WKE4
names: Subcellular Location Annotation
messages: Membrane