445932:EMIN RS03690
gene id: 445932:EMIN_RS03690
uniprot id: B2KCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

445932:EMIN RS07130
gene id: 445932:EMIN_RS07130
uniprot id: B2KEK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

445932:EMIN RS02990
gene id: 445932:EMIN_RS02990
uniprot id: B2KC06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

445932:EMIN RS06640
gene id: 445932:EMIN_RS06640
uniprot id: B2KEA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

445932:EMIN RS03250
gene id: 445932:EMIN_RS03250
uniprot id: B2KC58
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

445932:EMIN RS02080
gene id: 445932:EMIN_RS02080
uniprot id: B2KBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

445932:EMIN RS05690
gene id: 445932:EMIN_RS05690
uniprot id: B2KDS3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

445932:EMIN RS00615
gene id: 445932:EMIN_RS00615
uniprot id: B2KAZ0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

445932:EMIN RS00010
gene id: 445932:EMIN_RS00010
uniprot id: B2KAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

445932:EMIN RS02735
gene id: 445932:EMIN_RS02735
uniprot id: B2KCG1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

445932:EMIN RS05210
gene id: 445932:EMIN_RS05210
uniprot id: B2KDH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

445932:EMIN RS00270
gene id: 445932:EMIN_RS00270
uniprot id: B2KAS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

445932:EMIN RS05250
gene id: 445932:EMIN_RS05250
uniprot id: B2KDI4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

445932:EMIN RS07260
gene id: 445932:EMIN_RS07260
uniprot id: B2KEN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

445932:EMIN RS06345
gene id: 445932:EMIN_RS06345
uniprot id: B2KE50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

445932:EMIN RS07715
gene id: 445932:EMIN_RS07715
uniprot id: B2KEW3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS06950
gene id: 445932:EMIN_RS06950
uniprot id: B2KEG9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

445932:EMIN RS07820
gene id: 445932:EMIN_RS07820
uniprot id: B2KEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

445932:EMIN RS05765
gene id: 445932:EMIN_RS05765
uniprot id: B2KDT8
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

445932:EMIN RS05795
gene id: 445932:EMIN_RS05795
uniprot id: B2KDU4
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS01455
gene id: 445932:EMIN_RS01455
uniprot id: B2KBU4
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

445932:EMIN RS03635
gene id: 445932:EMIN_RS03635
uniprot id: B2KCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

445932:EMIN RS06490
gene id: 445932:EMIN_RS06490
uniprot id: B2KE79
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS06900
gene id: 445932:EMIN_RS06900
uniprot id: B2KEF9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

445932:EMIN RS00715
gene id: 445932:EMIN_RS00715
uniprot id: B2KBL7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

445932:EMIN RS05190
gene id: 445932:EMIN_RS05190
uniprot id: B2KDH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS01055
gene id: 445932:EMIN_RS01055
uniprot id: B2KB10
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

445932:EMIN RS05550
gene id: 445932:EMIN_RS05550
uniprot id: B2KDP4
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS06300
gene id: 445932:EMIN_RS06300
uniprot id: B2KE42
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

445932:EMIN RS00170
gene id: 445932:EMIN_RS00170
uniprot id: B2KAQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

445932:EMIN RS01845
gene id: 445932:EMIN_RS01845
uniprot id: B2KB97
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS08215
gene id: 445932:EMIN_RS08215
uniprot id: B2KCK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

445932:EMIN RS06705
gene id: 445932:EMIN_RS06705
uniprot id: B2KEC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

445932:EMIN RS03820
gene id: 445932:EMIN_RS03820
uniprot id: B2KCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

445932:EMIN RS06365
gene id: 445932:EMIN_RS06365
uniprot id: B2KE54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

445932:EMIN RS04025
gene id: 445932:EMIN_RS04025
uniprot id: B2KCU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS07190
gene id: 445932:EMIN_RS07190
uniprot id: B2KEL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

445932:EMIN RS03365
gene id: 445932:EMIN_RS03365
uniprot id: B2KC80
names: Similarity
messages: Belongs to the NAD synthetase family.

445932:EMIN RS03895
gene id: 445932:EMIN_RS03895
uniprot id: B2KCR4
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

445932:EMIN RS00670
gene id: 445932:EMIN_RS00670
uniprot id: B2KB01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

445932:EMIN RS02890
gene id: 445932:EMIN_RS02890
uniprot id: B2KCJ2
names: Similarity
messages: Belongs to the pyruvate kinase family.

445932:EMIN RS07155
gene id: 445932:EMIN_RS07155
uniprot id: B2KEL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

445932:EMIN RS06910
gene id: 445932:EMIN_RS06910
uniprot id: B2KEG1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS04340
gene id: 445932:EMIN_RS04340
uniprot id: B2KD05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

445932:EMIN RS00350
gene id: 445932:EMIN_RS00350
uniprot id: B2KAU0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

445932:EMIN RS02165
gene id: 445932:EMIN_RS02165
uniprot id: B2KBF5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

445932:EMIN RS06070
gene id: 445932:EMIN_RS06070
uniprot id: B2KDZ6
names: Similarity
messages: Belongs to the peptidase M29 family.

445932:EMIN RS04650
gene id: 445932:EMIN_RS04650
uniprot id: B2KD63
names: Similarity
messages: Belongs to the CTP synthase family.

445932:EMIN RS03395
gene id: 445932:EMIN_RS03395
uniprot id: B2KC86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

445932:EMIN RS08430
gene id: 445932:EMIN_RS08430
uniprot id: B2KE99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

445932:EMIN RS00220
gene id: 445932:EMIN_RS00220
uniprot id: B2KAR5
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS01195
gene id: 445932:EMIN_RS01195
uniprot id: B2KB39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

445932:EMIN RS06860
gene id: 445932:EMIN_RS06860
uniprot id: B2KEF1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

445932:EMIN RS05405
gene id: 445932:EMIN_RS05405
uniprot id: B2KDL4
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS06720
gene id: 445932:EMIN_RS06720
uniprot id: B2KEC5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

445932:EMIN RS02725
gene id: 445932:EMIN_RS02725
uniprot id: B2KCF9
names: Similarity
messages: Belongs to the DtxR/MntR family.

445932:EMIN RS00295
gene id: 445932:EMIN_RS00295
uniprot id: B2KAS9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS00665
gene id: 445932:EMIN_RS00665
uniprot id: B2KB00
names: Subcellular Location Annotation
messages: Cytoplasm

445932:EMIN RS05970
gene id: 445932:EMIN_RS05970
uniprot id: B2KDX7
names: Subcellular Location Annotation
messages: Cytoplasm

445932:EMIN RS03140
gene id: 445932:EMIN_RS03140
uniprot id: B2KC37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

445932:EMIN RS02670
gene id: 445932:EMIN_RS02670
uniprot id: B2KCE9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

445932:EMIN RS07085
gene id: 445932:EMIN_RS07085
uniprot id: B2KEJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

445932:EMIN RS01985
gene id: 445932:EMIN_RS01985
uniprot id: B2KBC2
names: Similarity
messages: Belongs to the RutC family.

445932:EMIN RS05365
gene id: 445932:EMIN_RS05365
uniprot id: B2KDK6
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS06865
gene id: 445932:EMIN_RS06865
uniprot id: B2KEF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS07265
gene id: 445932:EMIN_RS07265
uniprot id: B2KEN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

445932:EMIN RS07685
gene id: 445932:EMIN_RS07685
uniprot id: B2KEV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

445932:EMIN RS02915
gene id: 445932:EMIN_RS02915
uniprot id: B2KBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

445932:EMIN RS06730
gene id: 445932:EMIN_RS06730
uniprot id: B2KEC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

445932:EMIN RS01115
gene id: 445932:EMIN_RS01115
uniprot id: B2KB21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

445932:EMIN RS00945
gene id: 445932:EMIN_RS00945
uniprot id: B2KBR2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

445932:EMIN RS07805
gene id: 445932:EMIN_RS07805
uniprot id: B2KEY0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

445932:EMIN RS02810
gene id: 445932:EMIN_RS02810
uniprot id: B2KCH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

445932:EMIN RS02695
gene id: 445932:EMIN_RS02695
uniprot id: B2KCF3
names: Similarity
messages: Belongs to the GARS family.

445932:EMIN RS06620
gene id: 445932:EMIN_RS06620
uniprot id: B2KEA5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

445932:EMIN RS00775
gene id: 445932:EMIN_RS00775
uniprot id: B2KBM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

445932:EMIN RS05740
gene id: 445932:EMIN_RS05740
uniprot id: B2KDT3
names: Similarity
messages: Belongs to the peptidase A31 family.

445932:EMIN RS02575
gene id: 445932:EMIN_RS02575
uniprot id: B2KCD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS01230
gene id: 445932:EMIN_RS01230
uniprot id: B2KB46
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

445932:EMIN RS01235
gene id: 445932:EMIN_RS01235
uniprot id: B2KB47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

445932:EMIN RS01920
gene id: 445932:EMIN_RS01920
uniprot id: B2KBA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

445932:EMIN RS00420
gene id: 445932:EMIN_RS00420
uniprot id: B2KAV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

445932:EMIN RS03345
gene id: 445932:EMIN_RS03345
uniprot id: B2KC76
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

445932:EMIN RS05570
gene id: 445932:EMIN_RS05570
uniprot id: B2KDP8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

445932:EMIN RS00120
gene id: 445932:EMIN_RS00120
uniprot id: B2KAP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

445932:EMIN RS06920
gene id: 445932:EMIN_RS06920
uniprot id: B2KEG3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

445932:EMIN RS04425
gene id: 445932:EMIN_RS04425
uniprot id: B2KD23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

445932:EMIN RS00635
gene id: 445932:EMIN_RS00635
uniprot id: B2KAZ4
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

445932:EMIN RS00755
gene id: 445932:EMIN_RS00755
uniprot id: B2KBM5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

445932:EMIN RS03685
gene id: 445932:EMIN_RS03685
uniprot id: B2KCM5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

445932:EMIN RS02815
gene id: 445932:EMIN_RS02815
uniprot id: B2KCH7
names: Similarity
messages: Belongs to the GSP E family.

445932:EMIN RS03645
gene id: 445932:EMIN_RS03645
uniprot id: B2KCL7
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS02705
gene id: 445932:EMIN_RS02705
uniprot id: B2KCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

445932:EMIN RS02210
gene id: 445932:EMIN_RS02210
uniprot id: B2KBG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS04400
gene id: 445932:EMIN_RS04400
uniprot id: B2KD18
names: Similarity
messages: Belongs to the threonine synthase family.

445932:EMIN RS02710
gene id: 445932:EMIN_RS02710
uniprot id: B2KCF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS04305
gene id: 445932:EMIN_RS04305
uniprot id: B2KCZ8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

445932:EMIN RS06290
gene id: 445932:EMIN_RS06290
uniprot id: B2KE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

445932:EMIN RS08010
gene id: 445932:EMIN_RS08010
uniprot id: B2KBT6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

445932:EMIN RS03145
gene id: 445932:EMIN_RS03145
uniprot id: B2KC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

445932:EMIN RS04610
gene id: 445932:EMIN_RS04610
uniprot id: B2KD56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

445932:EMIN RS02660
gene id: 445932:EMIN_RS02660
uniprot id: B2KCE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

445932:EMIN RS01665
gene id: 445932:EMIN_RS01665
uniprot id: B2KBY2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

445932:EMIN RS05805
gene id: 445932:EMIN_RS05805
uniprot id: B2KDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

445932:EMIN RS04430
gene id: 445932:EMIN_RS04430
uniprot id: B2KD24
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

445932:EMIN RS04165
gene id: 445932:EMIN_RS04165
uniprot id: B2KCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

445932:EMIN RS04110
gene id: 445932:EMIN_RS04110
uniprot id: B2KCV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS02015
gene id: 445932:EMIN_RS02015
uniprot id: B2KBC8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

445932:EMIN RS00710
gene id: 445932:EMIN_RS00710
uniprot id: B2KBL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

445932:EMIN RS05545
gene id: 445932:EMIN_RS05545
uniprot id: B2KDP3
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS08195
gene id: 445932:EMIN_RS08195
uniprot id: B2KC81
names: Similarity
messages: Belongs to the peptidase S8 family.

445932:EMIN RS03480
gene id: 445932:EMIN_RS03480
uniprot id: B2KCA4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

445932:EMIN RS02720
gene id: 445932:EMIN_RS02720
uniprot id: B2KCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

445932:EMIN RS05750
gene id: 445932:EMIN_RS05750
uniprot id: B2KDT5
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS03540
gene id: 445932:EMIN_RS03540
uniprot id: B2KCJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

445932:EMIN RS06735
gene id: 445932:EMIN_RS06735
uniprot id: B2KEC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

445932:EMIN RS03745
gene id: 445932:EMIN_RS03745
uniprot id: B2KCN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

445932:EMIN RS07895
gene id: 445932:EMIN_RS07895
uniprot id: B2KEZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

445932:EMIN RS04655
gene id: 445932:EMIN_RS04655
uniprot id: B2KD64
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

445932:EMIN RS06195
gene id: 445932:EMIN_RS06195
uniprot id: B2KE21
names: Similarity
messages: Belongs to the peptidase S41A family.

445932:EMIN RS05280
gene id: 445932:EMIN_RS05280
uniprot id: B2KDI9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

445932:EMIN RS07250
gene id: 445932:EMIN_RS07250
uniprot id: B2KEN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

445932:EMIN RS07195
gene id: 445932:EMIN_RS07195
uniprot id: B2KEL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

445932:EMIN RS05455
gene id: 445932:EMIN_RS05455
uniprot id: B2KDM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

445932:EMIN RS00200
gene id: 445932:EMIN_RS00200
uniprot id: B2KAR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

445932:EMIN RS00515
gene id: 445932:EMIN_RS00515
uniprot id: B2KAX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

445932:EMIN RS05285
gene id: 445932:EMIN_RS05285
uniprot id: B2KDJ0
names: Similarity
messages: Belongs to the CarB family.

445932:EMIN RS00435
gene id: 445932:EMIN_RS00435
uniprot id: B2KAV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

445932:EMIN RS06575
gene id: 445932:EMIN_RS06575
uniprot id: B2KE96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS04660
gene id: 445932:EMIN_RS04660
uniprot id: B2KD65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

445932:EMIN RS03975
gene id: 445932:EMIN_RS03975
uniprot id: B2KCS9
names: Similarity
messages: Belongs to the glutamine synthetase family.

445932:EMIN RS01380
gene id: 445932:EMIN_RS01380
uniprot id: B2KBT0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

445932:EMIN RS02295
gene id: 445932:EMIN_RS02295
uniprot id: B2KBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

445932:EMIN RS07465
gene id: 445932:EMIN_RS07465
uniprot id: B2KER6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

445932:EMIN RS06020
gene id: 445932:EMIN_RS06020
uniprot id: B2KDY7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

445932:EMIN RS07635
gene id: 445932:EMIN_RS07635
uniprot id: B2KEU9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

445932:EMIN RS08075
gene id: 445932:EMIN_RS08075
uniprot id: B2KBE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

445932:EMIN RS06510
gene id: 445932:EMIN_RS06510
uniprot id: B2KE83
names: Subcellular Location Annotation
messages: Periplasm

445932:EMIN RS06745
gene id: 445932:EMIN_RS06745
uniprot id: B2KED0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

445932:EMIN RS01660
gene id: 445932:EMIN_RS01660
uniprot id: B2KBY1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

445932:EMIN RS03405
gene id: 445932:EMIN_RS03405
uniprot id: B2KC88
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

445932:EMIN RS00875
gene id: 445932:EMIN_RS00875
uniprot id: B2KBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

445932:EMIN RS07230
gene id: 445932:EMIN_RS07230
uniprot id: B2KEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

445932:EMIN RS03550
gene id: 445932:EMIN_RS03550
uniprot id: B2KCJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

445932:EMIN RS05630
gene id: 445932:EMIN_RS05630
uniprot id: B2KDR0
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS01805
gene id: 445932:EMIN_RS01805
uniprot id: B2KB90
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

445932:EMIN RS06410
gene id: 445932:EMIN_RS06410
uniprot id: B2KE63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

445932:EMIN RS04675
gene id: 445932:EMIN_RS04675
uniprot id: B2KD68
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05785
gene id: 445932:EMIN_RS05785
uniprot id: B2KDU2
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05920
gene id: 445932:EMIN_RS05920
uniprot id: B2KDW8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

445932:EMIN RS07875
gene id: 445932:EMIN_RS07875
uniprot id: B2KEZ3
names: Similarity
messages: Belongs to the ParB family.

445932:EMIN RS00940
gene id: 445932:EMIN_RS00940
uniprot id: B2KBR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

445932:EMIN RS07065
gene id: 445932:EMIN_RS07065
uniprot id: B2KEJ2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

445932:EMIN RS03660
gene id: 445932:EMIN_RS03660
uniprot id: B2KCM0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

445932:EMIN RS01935
gene id: 445932:EMIN_RS01935
uniprot id: B2KBB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

445932:EMIN RS04420
gene id: 445932:EMIN_RS04420
uniprot id: B2KD22
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

445932:EMIN RS06915
gene id: 445932:EMIN_RS06915
uniprot id: B2KEG2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

445932:EMIN RS07835
gene id: 445932:EMIN_RS07835
uniprot id: B2KEY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

445932:EMIN RS05305
gene id: 445932:EMIN_RS05305
uniprot id: B2KDJ4
names: Similarity
messages: Belongs to the Fur family.

445932:EMIN RS05950
gene id: 445932:EMIN_RS05950
uniprot id: B2KDX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

445932:EMIN RS07150
gene id: 445932:EMIN_RS07150
uniprot id: B2KEL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

445932:EMIN RS04680
gene id: 445932:EMIN_RS04680
uniprot id: B2KD69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

445932:EMIN RS07595
gene id: 445932:EMIN_RS07595
uniprot id: B2KEU2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

445932:EMIN RS07745
gene id: 445932:EMIN_RS07745
uniprot id: B2KEW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

445932:EMIN RS03780
gene id: 445932:EMIN_RS03780
uniprot id: B2KCP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

445932:EMIN RS04665
gene id: 445932:EMIN_RS04665
uniprot id: B2KD66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

445932:EMIN RS07640
gene id: 445932:EMIN_RS07640
uniprot id: B2KEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

445932:EMIN RS00025
gene id: 445932:EMIN_RS00025
uniprot id: B2KAM7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

445932:EMIN RS03630
gene id: 445932:EMIN_RS03630
uniprot id: B2KCL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

445932:EMIN RS03430
gene id: 445932:EMIN_RS03430
uniprot id: B2KC93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

445932:EMIN RS06700
gene id: 445932:EMIN_RS06700
uniprot id: B2KEC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

445932:EMIN RS06370
gene id: 445932:EMIN_RS06370
uniprot id: B2KE55
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS06145
gene id: 445932:EMIN_RS06145
uniprot id: B2KE11
names: Similarity
messages: Belongs to the bacterial secretin family.

445932:EMIN RS01980
gene id: 445932:EMIN_RS01980
uniprot id: B2KBC1
names: Similarity
messages: Belongs to the disproportionating enzyme family.

445932:EMIN RS02690
gene id: 445932:EMIN_RS02690
uniprot id: B2KCF2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS08795
gene id: 445932:EMIN_RS08795
uniprot id: B2KEJ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

445932:EMIN RS01815
gene id: 445932:EMIN_RS01815
uniprot id: B2KB92
names: Similarity
messages: Belongs to the transketolase family.

445932:EMIN RS00730
gene id: 445932:EMIN_RS00730
uniprot id: B2KBM0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

445932:EMIN RS01440
gene id: 445932:EMIN_RS01440
uniprot id: B2KBU1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

445932:EMIN RS06210
gene id: 445932:EMIN_RS06210
uniprot id: B2KE24
names: Similarity
messages: Belongs to the alkaline phosphatase family.

445932:EMIN RS06825
gene id: 445932:EMIN_RS06825
uniprot id: B2KEE5
names: Similarity
messages: Belongs to the UPF0235 family.

445932:EMIN RS02510
gene id: 445932:EMIN_RS02510
uniprot id: B2KCC0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

445932:EMIN RS06940
gene id: 445932:EMIN_RS06940
uniprot id: B2KEG7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

445932:EMIN RS00320
gene id: 445932:EMIN_RS00320
uniprot id: B2KAT4
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

445932:EMIN RS07720
gene id: 445932:EMIN_RS07720
uniprot id: B2KEW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

445932:EMIN RS00315
gene id: 445932:EMIN_RS00315
uniprot id: B2KAT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

445932:EMIN RS03985
gene id: 445932:EMIN_RS03985
uniprot id: B2KCT1
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

445932:EMIN RS03195
gene id: 445932:EMIN_RS03195
uniprot id: B2KC48
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

445932:EMIN RS04725
gene id: 445932:EMIN_RS04725
uniprot id: B2KD77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

445932:EMIN RS02630
gene id: 445932:EMIN_RS02630
uniprot id: B2KCE3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS01450
gene id: 445932:EMIN_RS01450
uniprot id: B2KBU3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

445932:EMIN RS05180
gene id: 445932:EMIN_RS05180
uniprot id: B2KDH0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

445932:EMIN RS03110
gene id: 445932:EMIN_RS03110
uniprot id: B2KC31
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

445932:EMIN RS06235
gene id: 445932:EMIN_RS06235
uniprot id: B2KE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

445932:EMIN RS01070
gene id: 445932:EMIN_RS01070
uniprot id: B2KB12
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

445932:EMIN RS07660
gene id: 445932:EMIN_RS07660
uniprot id: B2KEV2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

445932:EMIN RS03435
gene id: 445932:EMIN_RS03435
uniprot id: B2KC94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

445932:EMIN RS03400
gene id: 445932:EMIN_RS03400
uniprot id: B2KC87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

445932:EMIN RS05295
gene id: 445932:EMIN_RS05295
uniprot id: B2KDJ2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

445932:EMIN RS02190
gene id: 445932:EMIN_RS02190
uniprot id: B2KBF8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

445932:EMIN RS02125
gene id: 445932:EMIN_RS02125
uniprot id: B2KBE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

445932:EMIN RS04395
gene id: 445932:EMIN_RS04395
uniprot id: B2KD17
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

445932:EMIN RS07235
gene id: 445932:EMIN_RS07235
uniprot id: B2KEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

445932:EMIN RS05655
gene id: 445932:EMIN_RS05655
uniprot id: B2KDR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

445932:EMIN RS06870
gene id: 445932:EMIN_RS06870
uniprot id: B2KEF3
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS07775
gene id: 445932:EMIN_RS07775
uniprot id: B2KEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

445932:EMIN RS05820
gene id: 445932:EMIN_RS05820
uniprot id: B2KDU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

445932:EMIN RS00510
gene id: 445932:EMIN_RS00510
uniprot id: B2KAX0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

445932:EMIN RS08020
gene id: 445932:EMIN_RS08020
uniprot id: B2KBV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS00960
gene id: 445932:EMIN_RS00960
uniprot id: B2KBR5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

445932:EMIN RS02865
gene id: 445932:EMIN_RS02865
uniprot id: B2KCI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS02140
gene id: 445932:EMIN_RS02140
uniprot id: B2KBF0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

445932:EMIN RS00520
gene id: 445932:EMIN_RS00520
uniprot id: B2KAX2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

445932:EMIN RS07510
gene id: 445932:EMIN_RS07510
uniprot id: B2KES5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

445932:EMIN RS03755
gene id: 445932:EMIN_RS03755
uniprot id: B2KCN7
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

445932:EMIN RS01900
gene id: 445932:EMIN_RS01900
uniprot id: B2KBA5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

445932:EMIN RS05445
gene id: 445932:EMIN_RS05445
uniprot id: B2KDM3
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05380
gene id: 445932:EMIN_RS05380
uniprot id: B2KDK9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

445932:EMIN RS06470
gene id: 445932:EMIN_RS06470
uniprot id: B2KE75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

445932:EMIN RS07025
gene id: 445932:EMIN_RS07025
uniprot id: B2KEI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

445932:EMIN RS01520
gene id: 445932:EMIN_RS01520
uniprot id: B2KBV4
names: Similarity
messages: Belongs to the class-I fumarase family.

445932:EMIN RS07160
gene id: 445932:EMIN_RS07160
uniprot id: B2KEL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

445932:EMIN RS06955
gene id: 445932:EMIN_RS06955
uniprot id: B2KEH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

445932:EMIN RS05830
gene id: 445932:EMIN_RS05830
uniprot id: B2KDV1
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS03075
gene id: 445932:EMIN_RS03075
uniprot id: B2KC24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

445932:EMIN RS03535
gene id: 445932:EMIN_RS03535
uniprot id: B2KCJ5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

445932:EMIN RS07630
gene id: 445932:EMIN_RS07630
uniprot id: B2KEU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

445932:EMIN RS00780
gene id: 445932:EMIN_RS00780
uniprot id: B2KBN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

445932:EMIN RS06710
gene id: 445932:EMIN_RS06710
uniprot id: B2KEC3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS02005
gene id: 445932:EMIN_RS02005
uniprot id: B2KBC6
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

445932:EMIN RS02265
gene id: 445932:EMIN_RS02265
uniprot id: B2KBH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

445932:EMIN RS05665
gene id: 445932:EMIN_RS05665
uniprot id: B2KDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

445932:EMIN RS06285
gene id: 445932:EMIN_RS06285
uniprot id: B2KE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

445932:EMIN RS04295
gene id: 445932:EMIN_RS04295
uniprot id: B2KCZ6
names: Similarity
messages: Belongs to the guanylate kinase family.

445932:EMIN RS02205
gene id: 445932:EMIN_RS02205
uniprot id: B2KBG1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

445932:EMIN RS01240
gene id: 445932:EMIN_RS01240
uniprot id: B2KB48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

445932:EMIN RS07440
gene id: 445932:EMIN_RS07440
uniprot id: B2KER1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

445932:EMIN RS06250
gene id: 445932:EMIN_RS06250
uniprot id: B2KE32
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

445932:EMIN RS07095
gene id: 445932:EMIN_RS07095
uniprot id: B2KEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

445932:EMIN RS05265
gene id: 445932:EMIN_RS05265
uniprot id: B2KDI6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS01445
gene id: 445932:EMIN_RS01445
uniprot id: B2KBU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

445932:EMIN RS04050
gene id: 445932:EMIN_RS04050
uniprot id: B2KCU5
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS06560
gene id: 445932:EMIN_RS06560
uniprot id: B2KE93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

445932:EMIN RS07360
gene id: 445932:EMIN_RS07360
uniprot id: B2KEP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

445932:EMIN RS05580
gene id: 445932:EMIN_RS05580
uniprot id: B2KDQ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

445932:EMIN RS00345
gene id: 445932:EMIN_RS00345
uniprot id: B2KAT9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

445932:EMIN RS03825
gene id: 445932:EMIN_RS03825
uniprot id: B2KCQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

445932:EMIN RS04715
gene id: 445932:EMIN_RS04715
uniprot id: B2KD75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

445932:EMIN RS04590
gene id: 445932:EMIN_RS04590
uniprot id: B2KD53
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

445932:EMIN RS05360
gene id: 445932:EMIN_RS05360
uniprot id: B2KDK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

445932:EMIN RS04210
gene id: 445932:EMIN_RS04210
uniprot id: B2KCX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

445932:EMIN RS00100
gene id: 445932:EMIN_RS00100
uniprot id: B2KAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

445932:EMIN RS02135
gene id: 445932:EMIN_RS02135
uniprot id: B2KBE9
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS00855
gene id: 445932:EMIN_RS00855
uniprot id: B2KBP5
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

445932:EMIN RS07500
gene id: 445932:EMIN_RS07500
uniprot id: B2KES3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

445932:EMIN RS06190
gene id: 445932:EMIN_RS06190
uniprot id: B2KE20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

445932:EMIN RS07695
gene id: 445932:EMIN_RS07695
uniprot id: B2KEV9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

445932:EMIN RS04065
gene id: 445932:EMIN_RS04065
uniprot id: B2KCU8
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

445932:EMIN RS01180
gene id: 445932:EMIN_RS01180
uniprot id: B2KB36
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

445932:EMIN RS01850
gene id: 445932:EMIN_RS01850
uniprot id: B2KB98
names: Similarity
messages: Belongs to the UPF0162 family.

445932:EMIN RS03725
gene id: 445932:EMIN_RS03725
uniprot id: B2KCN1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

445932:EMIN RS00375
gene id: 445932:EMIN_RS00375
uniprot id: B2KAU5
names: Similarity
messages: Belongs to the Skp family.

445932:EMIN RS07110
gene id: 445932:EMIN_RS07110
uniprot id: B2KEK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

445932:EMIN RS03185
gene id: 445932:EMIN_RS03185
uniprot id: B2KC46
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

445932:EMIN RS02150
gene id: 445932:EMIN_RS02150
uniprot id: B2KBF2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS04200
gene id: 445932:EMIN_RS04200
uniprot id: B2KCX6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

445932:EMIN RS03865
gene id: 445932:EMIN_RS03865
uniprot id: B2KCQ8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

445932:EMIN RS06820
gene id: 445932:EMIN_RS06820
uniprot id: B2KEE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

445932:EMIN RS06610
gene id: 445932:EMIN_RS06610
uniprot id: B2KEA3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

445932:EMIN RS04645
gene id: 445932:EMIN_RS04645
uniprot id: B2KD62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

445932:EMIN RS03285
gene id: 445932:EMIN_RS03285
uniprot id: B2KC64
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

445932:EMIN RS02285
gene id: 445932:EMIN_RS02285
uniprot id: B2KBH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

445932:EMIN RS00805
gene id: 445932:EMIN_RS00805
uniprot id: B2KBN5
names: Similarity
messages: Belongs to the DprA/Smf family.

445932:EMIN RS05350
gene id: 445932:EMIN_RS05350
uniprot id: B2KDK3
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05650
gene id: 445932:EMIN_RS05650
uniprot id: B2KDR5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

445932:EMIN RS04735
gene id: 445932:EMIN_RS04735
uniprot id: B2KD79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

445932:EMIN RS03655
gene id: 445932:EMIN_RS03655
uniprot id: B2KCL9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

445932:EMIN RS00550
gene id: 445932:EMIN_RS00550
uniprot id: B2KAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

445932:EMIN RS07365
gene id: 445932:EMIN_RS07365
uniprot id: B2KEP6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

445932:EMIN RS01770
gene id: 445932:EMIN_RS01770
uniprot id: B2KB84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

445932:EMIN RS05755
gene id: 445932:EMIN_RS05755
uniprot id: B2KDT6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

445932:EMIN RS00650
gene id: 445932:EMIN_RS00650
uniprot id: B2KAZ7
names: Subcellular Location Annotation
messages: Cytoplasm

445932:EMIN RS03485
gene id: 445932:EMIN_RS03485
uniprot id: B2KCA5
names: Similarity
messages: Belongs to the ribF family.

445932:EMIN RS01420
gene id: 445932:EMIN_RS01420
uniprot id: B2KBT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

445932:EMIN RS01355
gene id: 445932:EMIN_RS01355
uniprot id: B2KBS7
names: Similarity
messages: Belongs to the LOG family.

445932:EMIN RS07020
gene id: 445932:EMIN_RS07020
uniprot id: B2KEI4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

445932:EMIN RS06230
gene id: 445932:EMIN_RS06230
uniprot id: B2KE28
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

445932:EMIN RS07770
gene id: 445932:EMIN_RS07770
uniprot id: B2KEX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

445932:EMIN RS05670
gene id: 445932:EMIN_RS05670
uniprot id: B2KDR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

445932:EMIN RS01650
gene id: 445932:EMIN_RS01650
uniprot id: B2KBX9
names: Similarity
messages: Belongs to the CapA family.

445932:EMIN RS00580
gene id: 445932:EMIN_RS00580
uniprot id: B2KAY4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

445932:EMIN RS00165
gene id: 445932:EMIN_RS00165
uniprot id: B2KAQ4
names: Similarity
messages: Belongs to the peptidase S49 family.

445932:EMIN RS07620
gene id: 445932:EMIN_RS07620
uniprot id: B2KEU6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

445932:EMIN RS01995
gene id: 445932:EMIN_RS01995
uniprot id: B2KBC4
names: Similarity
messages: Belongs to the HypD family.

445932:EMIN RS03620
gene id: 445932:EMIN_RS03620
uniprot id: B2KCL2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

445932:EMIN RS04630
gene id: 445932:EMIN_RS04630
uniprot id: B2KD59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

445932:EMIN RS07505
gene id: 445932:EMIN_RS07505
uniprot id: B2KES4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

445932:EMIN RS03000
gene id: 445932:EMIN_RS03000
uniprot id: B2KC08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

445932:EMIN RS05275
gene id: 445932:EMIN_RS05275
uniprot id: B2KDI8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

445932:EMIN RS03570
gene id: 445932:EMIN_RS03570
uniprot id: B2KCK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

445932:EMIN RS08420
gene id: 445932:EMIN_RS08420
uniprot id: B2KE67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

445932:EMIN RS00145
gene id: 445932:EMIN_RS00145
uniprot id: B2KAQ0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

445932:EMIN RS06960
gene id: 445932:EMIN_RS06960
uniprot id: B2KEH1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

445932:EMIN RS02565
gene id: 445932:EMIN_RS02565
uniprot id: B2KCD1
names: Similarity
messages: Belongs to the thioredoxin family.

445932:EMIN RS01515
gene id: 445932:EMIN_RS01515
uniprot id: B2KBV3
names: Similarity
messages: Belongs to the class-I fumarase family.

445932:EMIN RS00455
gene id: 445932:EMIN_RS00455
uniprot id: B2KAW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

445932:EMIN RS00265
gene id: 445932:EMIN_RS00265
uniprot id: B2KAS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

445932:EMIN RS01990
gene id: 445932:EMIN_RS01990
uniprot id: B2KBC3
names: Similarity
messages: Belongs to the HupF/HypC family.

445932:EMIN RS02910
gene id: 445932:EMIN_RS02910
uniprot id: B2KBZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

445932:EMIN RS00275
gene id: 445932:EMIN_RS00275
uniprot id: B2KAS5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

445932:EMIN RS01745
gene id: 445932:EMIN_RS01745
uniprot id: B2KB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

445932:EMIN RS06350
gene id: 445932:EMIN_RS06350
uniprot id: B2KE51
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

445932:EMIN RS04925
gene id: 445932:EMIN_RS04925
uniprot id: B2KDB6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

445932:EMIN RS01350
gene id: 445932:EMIN_RS01350
uniprot id: B2KBS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

445932:EMIN RS07890
gene id: 445932:EMIN_RS07890
uniprot id: B2KEZ6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

445932:EMIN RS07180
gene id: 445932:EMIN_RS07180
uniprot id: B2KEL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

445932:EMIN RS06715
gene id: 445932:EMIN_RS06715
uniprot id: B2KEC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

445932:EMIN RS06875
gene id: 445932:EMIN_RS06875
uniprot id: B2KEF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

445932:EMIN RS02435
gene id: 445932:EMIN_RS02435
uniprot id: B2KBK4
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

445932:EMIN RS04730
gene id: 445932:EMIN_RS04730
uniprot id: B2KD78
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS07495
gene id: 445932:EMIN_RS07495
uniprot id: B2KES2
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS00280
gene id: 445932:EMIN_RS00280
uniprot id: B2KAS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

445932:EMIN RS07005
gene id: 445932:EMIN_RS07005
uniprot id: B2KEI1
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS00225
gene id: 445932:EMIN_RS00225
uniprot id: B2KAR6
names: Similarity
messages: Belongs to the UPF0111 family.

445932:EMIN RS00810
gene id: 445932:EMIN_RS00810
uniprot id: B2KBN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

445932:EMIN RS04370
gene id: 445932:EMIN_RS04370
uniprot id: B2KD12
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05395
gene id: 445932:EMIN_RS05395
uniprot id: B2KDL2
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

445932:EMIN RS06010
gene id: 445932:EMIN_RS06010
uniprot id: B2KDY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

445932:EMIN RS03845
gene id: 445932:EMIN_RS03845
uniprot id: B2KCQ4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

445932:EMIN RS07015
gene id: 445932:EMIN_RS07015
uniprot id: B2KEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

445932:EMIN RS06405
gene id: 445932:EMIN_RS06405
uniprot id: B2KE62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

445932:EMIN RS04745
gene id: 445932:EMIN_RS04745
uniprot id: B2KD81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

445932:EMIN RS04750
gene id: 445932:EMIN_RS04750
uniprot id: B2KD82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

445932:EMIN RS02745
gene id: 445932:EMIN_RS02745
uniprot id: B2KCG3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

445932:EMIN RS04150
gene id: 445932:EMIN_RS04150
uniprot id: B2KCW5
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

445932:EMIN RS04405
gene id: 445932:EMIN_RS04405
uniprot id: B2KD19
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

445932:EMIN RS07460
gene id: 445932:EMIN_RS07460
uniprot id: B2KER5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS07960
gene id: 445932:EMIN_RS07960
uniprot id: B2KAZ9
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS00570
gene id: 445932:EMIN_RS00570
uniprot id: B2KAY2
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS07540
gene id: 445932:EMIN_RS07540
uniprot id: B2KET1
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS03390
gene id: 445932:EMIN_RS03390
uniprot id: B2KC85
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

445932:EMIN RS07490
gene id: 445932:EMIN_RS07490
uniprot id: B2KES1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

445932:EMIN RS01140
gene id: 445932:EMIN_RS01140
uniprot id: B2KB27
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

445932:EMIN RS03440
gene id: 445932:EMIN_RS03440
uniprot id: B2KC95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

445932:EMIN RS07575
gene id: 445932:EMIN_RS07575
uniprot id: B2KET8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

445932:EMIN RS05370
gene id: 445932:EMIN_RS05370
uniprot id: B2KDK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

445932:EMIN RS05415
gene id: 445932:EMIN_RS05415
uniprot id: B2KDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

445932:EMIN RS02920
gene id: 445932:EMIN_RS02920
uniprot id: B2KBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

445932:EMIN RS07060
gene id: 445932:EMIN_RS07060
uniprot id: B2KEJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

445932:EMIN RS02030
gene id: 445932:EMIN_RS02030
uniprot id: B2KBD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS06500
gene id: 445932:EMIN_RS06500
uniprot id: B2KE81
names: Similarity
messages: Belongs to the Pal lipoprotein family.

445932:EMIN RS06245
gene id: 445932:EMIN_RS06245
uniprot id: B2KE31
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

445932:EMIN RS01275
gene id: 445932:EMIN_RS01275
uniprot id: B2KB56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

445932:EMIN RS02805
gene id: 445932:EMIN_RS02805
uniprot id: B2KCH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

445932:EMIN RS08915
gene id: 445932:EMIN_RS08915
uniprot id: B2KDC6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

445932:EMIN RS00675
gene id: 445932:EMIN_RS00675
uniprot id: B2KB02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

445932:EMIN RS03270
gene id: 445932:EMIN_RS03270
uniprot id: B2KC61
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

445932:EMIN RS01975
gene id: 445932:EMIN_RS01975
uniprot id: B2KBC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS02320
gene id: 445932:EMIN_RS02320
uniprot id: B2KBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell inner membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

445932:EMIN RS04030
gene id: 445932:EMIN_RS04030
uniprot id: B2KCU1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

445932:EMIN RS03245
gene id: 445932:EMIN_RS03245
uniprot id: B2KC57
names: Similarity
messages: Belongs to the UPF0102 family.

445932:EMIN RS01830
gene id: 445932:EMIN_RS01830
uniprot id: B2KB94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

445932:EMIN RS01680
gene id: 445932:EMIN_RS01680
uniprot id: B2KBY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

445932:EMIN RS01410
gene id: 445932:EMIN_RS01410
uniprot id: B2KBT5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

445932:EMIN RS00770
gene id: 445932:EMIN_RS00770
uniprot id: B2KBM8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

445932:EMIN RS00620
gene id: 445932:EMIN_RS00620
uniprot id: B2KAZ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

445932:EMIN RS01010
gene id: 445932:EMIN_RS01010
uniprot id: B2KB03
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

445932:EMIN RS02405
gene id: 445932:EMIN_RS02405
uniprot id: B2KBJ8
names: Similarity
messages: Belongs to the barstar family.

445932:EMIN RS05995
gene id: 445932:EMIN_RS05995
uniprot id: B2KDY2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

445932:EMIN RS03465
gene id: 445932:EMIN_RS03465
uniprot id: B2KCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

445932:EMIN RS00640
gene id: 445932:EMIN_RS00640
uniprot id: B2KAZ5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

445932:EMIN RS00870
gene id: 445932:EMIN_RS00870
uniprot id: B2KBP8
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS03680
gene id: 445932:EMIN_RS03680
uniprot id: B2KCM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

445932:EMIN RS06665
gene id: 445932:EMIN_RS06665
uniprot id: B2KEB4
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS04285
gene id: 445932:EMIN_RS04285
uniprot id: B2KCZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

445932:EMIN RS01890
gene id: 445932:EMIN_RS01890
uniprot id: B2KBA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

445932:EMIN RS07450
gene id: 445932:EMIN_RS07450
uniprot id: B2KER3
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

445932:EMIN RS08275
gene id: 445932:EMIN_RS08275
uniprot id: B2KD55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

445932:EMIN RS07170
gene id: 445932:EMIN_RS07170
uniprot id: B2KEL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

445932:EMIN RS00075
gene id: 445932:EMIN_RS00075
uniprot id: B2KAN6
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

445932:EMIN RS06835
gene id: 445932:EMIN_RS06835
uniprot id: B2KEE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS00385
gene id: 445932:EMIN_RS00385
uniprot id: B2KAU7
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

445932:EMIN RS07455
gene id: 445932:EMIN_RS07455
uniprot id: B2KER4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

445932:EMIN RS07755
gene id: 445932:EMIN_RS07755
uniprot id: B2KEX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

445932:EMIN RS08495
gene id: 445932:EMIN_RS08495
uniprot id: B2KES0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

445932:EMIN RS05875
gene id: 445932:EMIN_RS05875
uniprot id: B2KDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

445932:EMIN RS01460
gene id: 445932:EMIN_RS01460
uniprot id: B2KBU5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

445932:EMIN RS07205
gene id: 445932:EMIN_RS07205
uniprot id: B2KEM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

445932:EMIN RS06435
gene id: 445932:EMIN_RS06435
uniprot id: B2KE68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

445932:EMIN RS01945
gene id: 445932:EMIN_RS01945
uniprot id: B2KBB4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

445932:EMIN RS07765
gene id: 445932:EMIN_RS07765
uniprot id: B2KEX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

445932:EMIN RS02465
gene id: 445932:EMIN_RS02465
uniprot id: B2KBL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

445932:EMIN RS06395
gene id: 445932:EMIN_RS06395
uniprot id: B2KE60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

445932:EMIN RS07135
gene id: 445932:EMIN_RS07135
uniprot id: B2KEK6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

445932:EMIN RS00540
gene id: 445932:EMIN_RS00540
uniprot id: B2KAX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

445932:EMIN RS02045
gene id: 445932:EMIN_RS02045
uniprot id: B2KBD3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

445932:EMIN RS04785
gene id: 445932:EMIN_RS04785
uniprot id: B2KD89
names: Similarity
messages: Belongs to the beta-eliminating lyase family.

445932:EMIN RS07175
gene id: 445932:EMIN_RS07175
uniprot id: B2KEL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

445932:EMIN RS01600
gene id: 445932:EMIN_RS01600
uniprot id: B2KBX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

445932:EMIN RS03900
gene id: 445932:EMIN_RS03900
uniprot id: B2KCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

445932:EMIN RS03315
gene id: 445932:EMIN_RS03315
uniprot id: B2KC70
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

445932:EMIN RS01925
gene id: 445932:EMIN_RS01925
uniprot id: B2KBB0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

445932:EMIN RS00445
gene id: 445932:EMIN_RS00445
uniprot id: B2KAV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS07070
gene id: 445932:EMIN_RS07070
uniprot id: B2KEJ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

445932:EMIN RS07035
gene id: 445932:EMIN_RS07035
uniprot id: B2KEI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

445932:EMIN RS01940
gene id: 445932:EMIN_RS01940
uniprot id: B2KBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

445932:EMIN RS05885
gene id: 445932:EMIN_RS05885
uniprot id: B2KDW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

445932:EMIN RS06415
gene id: 445932:EMIN_RS06415
uniprot id: B2KE64
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS00655
gene id: 445932:EMIN_RS00655
uniprot id: B2KAZ8
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS07075
gene id: 445932:EMIN_RS07075
uniprot id: B2KEJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

445932:EMIN RS02700
gene id: 445932:EMIN_RS02700
uniprot id: B2KCF4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

445932:EMIN RS02995
gene id: 445932:EMIN_RS02995
uniprot id: B2KC07
names: Similarity
messages: Belongs to the GSP E family.

445932:EMIN RS01765
gene id: 445932:EMIN_RS01765
uniprot id: B2KB83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

445932:EMIN RS02590
gene id: 445932:EMIN_RS02590
uniprot id: B2KCD6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

445932:EMIN RS01810
gene id: 445932:EMIN_RS01810
uniprot id: B2KB91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

445932:EMIN RS03055
gene id: 445932:EMIN_RS03055
uniprot id: B2KC19
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

445932:EMIN RS07700
gene id: 445932:EMIN_RS07700
uniprot id: B2KEW0
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

445932:EMIN RS05935
gene id: 445932:EMIN_RS05935
uniprot id: B2KDX1
names: Caution
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS08090
gene id: 445932:EMIN_RS08090
uniprot id: B2KBH3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

445932:EMIN RS00240
gene id: 445932:EMIN_RS00240
uniprot id: B2KAR9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

445932:EMIN RS00705
gene id: 445932:EMIN_RS00705
uniprot id: B2KBL5
names: Similarity
messages: Belongs to the UPF0234 family.

445932:EMIN RS03525
gene id: 445932:EMIN_RS03525
uniprot id: B2KCB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS03605
gene id: 445932:EMIN_RS03605
uniprot id: B2KCK9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

445932:EMIN RS00030
gene id: 445932:EMIN_RS00030
uniprot id: B2KAM8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

445932:EMIN RS00830
gene id: 445932:EMIN_RS00830
uniprot id: B2KBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

445932:EMIN RS03470
gene id: 445932:EMIN_RS03470
uniprot id: B2KCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

445932:EMIN RS02275
gene id: 445932:EMIN_RS02275
uniprot id: B2KBH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

445932:EMIN RS01125
gene id: 445932:EMIN_RS01125
uniprot id: B2KB23
names: Similarity
messages: Belongs to the SAICAR synthetase family.

445932:EMIN RS05835
gene id: 445932:EMIN_RS05835
uniprot id: B2KDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

445932:EMIN RS06925
gene id: 445932:EMIN_RS06925
uniprot id: B2KEG4
names: Function
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

445932:EMIN RS03930
gene id: 445932:EMIN_RS03930
uniprot id: B2KCS0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

445932:EMIN RS04905
gene id: 445932:EMIN_RS04905
uniprot id: B2KDB1
names: Similarity
messages: Belongs to the peptidase S14 family.

445932:EMIN RS02965
gene id: 445932:EMIN_RS02965
uniprot id: B2KC01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

445932:EMIN RS01375
gene id: 445932:EMIN_RS01375
uniprot id: B2KBS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS01025
gene id: 445932:EMIN_RS01025
uniprot id: B2KB05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

445932:EMIN RS02625
gene id: 445932:EMIN_RS02625
uniprot id: B2KCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

445932:EMIN RS06935
gene id: 445932:EMIN_RS06935
uniprot id: B2KEG6
names: Similarity
messages: Belongs to the UPF0758 family.

445932:EMIN RS07565
gene id: 445932:EMIN_RS07565
uniprot id: B2KET6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

445932:EMIN RS05330
gene id: 445932:EMIN_RS05330
uniprot id: B2KDJ9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

445932:EMIN RS02610
gene id: 445932:EMIN_RS02610
uniprot id: B2KCD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

445932:EMIN RS03240
gene id: 445932:EMIN_RS03240
uniprot id: B2KC56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

445932:EMIN RS05685
gene id: 445932:EMIN_RS05685
uniprot id: B2KDS2
names: Similarity
messages: Belongs to the GPI family.

445932:EMIN RS05375
gene id: 445932:EMIN_RS05375
uniprot id: B2KDK8
names: Similarity
messages: Belongs to the hemerythrin family.

445932:EMIN RS05575
gene id: 445932:EMIN_RS05575
uniprot id: B2KDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

445932:EMIN RS00185
gene id: 445932:EMIN_RS00185
uniprot id: B2KAQ8
names: Similarity
messages: Belongs to the DapB family.

445932:EMIN RS06475
gene id: 445932:EMIN_RS06475
uniprot id: B2KE76
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

445932:EMIN RS02040
gene id: 445932:EMIN_RS02040
uniprot id: B2KBD2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

445932:EMIN RS02755
gene id: 445932:EMIN_RS02755
uniprot id: B2KCG5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

445932:EMIN RS01330
gene id: 445932:EMIN_RS01330
uniprot id: B2KB67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

445932:EMIN RS01540
gene id: 445932:EMIN_RS01540
uniprot id: B2KBV8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

445932:EMIN RS07255
gene id: 445932:EMIN_RS07255
uniprot id: B2KEN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

445932:EMIN RS04495
gene id: 445932:EMIN_RS04495
uniprot id: B2KD37
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

445932:EMIN RS06380
gene id: 445932:EMIN_RS06380
uniprot id: B2KE57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS02035
gene id: 445932:EMIN_RS02035
uniprot id: B2KBD1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

445932:EMIN RS03760
gene id: 445932:EMIN_RS03760
uniprot id: B2KCN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS07370
gene id: 445932:EMIN_RS07370
uniprot id: B2KEP7
names: Similarity
messages: Belongs to the UPF0047 family.

445932:EMIN RS07165
gene id: 445932:EMIN_RS07165
uniprot id: B2KEL3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

445932:EMIN RS03615
gene id: 445932:EMIN_RS03615
uniprot id: B2KCL1
names: Similarity
messages: Belongs to the peptidase S13 family.

445932:EMIN RS07200
gene id: 445932:EMIN_RS07200
uniprot id: B2KEM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

445932:EMIN RS03555
gene id: 445932:EMIN_RS03555
uniprot id: B2KCJ9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

445932:EMIN RS07045
gene id: 445932:EMIN_RS07045
uniprot id: B2KEI8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

445932:EMIN RS05865
gene id: 445932:EMIN_RS05865
uniprot id: B2KDV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

445932:EMIN RS03350
gene id: 445932:EMIN_RS03350
uniprot id: B2KC77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

445932:EMIN RS00015
gene id: 445932:EMIN_RS00015
uniprot id: B2KAM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

445932:EMIN RS03640
gene id: 445932:EMIN_RS03640
uniprot id: B2KCL6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS01000
gene id: 445932:EMIN_RS01000
uniprot id: B2KBS3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

445932:EMIN RS00360
gene id: 445932:EMIN_RS00360
uniprot id: B2KAU2
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS06460
gene id: 445932:EMIN_RS06460
uniprot id: B2KE73
names: Similarity
messages: Belongs to the phosphohexose mutase family.

445932:EMIN RS02615
gene id: 445932:EMIN_RS02615
uniprot id: B2KCE0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

445932:EMIN RS06570
gene id: 445932:EMIN_RS06570
uniprot id: B2KE95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

445932:EMIN RS04410
gene id: 445932:EMIN_RS04410
uniprot id: B2KD20
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

445932:EMIN RS06890
gene id: 445932:EMIN_RS06890
uniprot id: B2KEF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

445932:EMIN RS00815
gene id: 445932:EMIN_RS00815
uniprot id: B2KBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

445932:EMIN RS02930
gene id: 445932:EMIN_RS02930
uniprot id: B2KBZ4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS07185
gene id: 445932:EMIN_RS07185
uniprot id: B2KEL7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

445932:EMIN RS06130
gene id: 445932:EMIN_RS06130
uniprot id: B2KE08
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05980
gene id: 445932:EMIN_RS05980
uniprot id: B2KDX9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

445932:EMIN RS07790
gene id: 445932:EMIN_RS07790
uniprot id: B2KEX7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

445932:EMIN RS04315
gene id: 445932:EMIN_RS04315
uniprot id: B2KD00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS08070
gene id: 445932:EMIN_RS08070
uniprot id: B2KBD4
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05695
gene id: 445932:EMIN_RS05695
uniprot id: B2KDS4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

445932:EMIN RS00215
gene id: 445932:EMIN_RS00215
uniprot id: B2KAR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

445932:EMIN RS07785
gene id: 445932:EMIN_RS07785
uniprot id: B2KEX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

445932:EMIN RS04310
gene id: 445932:EMIN_RS04310
uniprot id: B2KCZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

445932:EMIN RS06215
gene id: 445932:EMIN_RS06215
uniprot id: B2KE25
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

445932:EMIN RS05160
gene id: 445932:EMIN_RS05160
uniprot id: B2KDG6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

445932:EMIN RS05170
gene id: 445932:EMIN_RS05170
uniprot id: B2KDG8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

445932:EMIN RS04620
gene id: 445932:EMIN_RS04620
uniprot id: B2KD57
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

445932:EMIN RS07030
gene id: 445932:EMIN_RS07030
uniprot id: B2KEI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

445932:EMIN RS02065
gene id: 445932:EMIN_RS02065
uniprot id: B2KBD7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

445932:EMIN RS07935
gene id: 445932:EMIN_RS07935
uniprot id: B2KAN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

445932:EMIN RS07245
gene id: 445932:EMIN_RS07245
uniprot id: B2KEM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

445932:EMIN RS04320
gene id: 445932:EMIN_RS04320
uniprot id: B2KD01
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

445932:EMIN RS04280
gene id: 445932:EMIN_RS04280
uniprot id: B2KCZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

445932:EMIN RS04355
gene id: 445932:EMIN_RS04355
uniprot id: B2KD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

445932:EMIN RS03120
gene id: 445932:EMIN_RS03120
uniprot id: B2KC33
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS00785
gene id: 445932:EMIN_RS00785
uniprot id: B2KBN1
names: Function
names: Similarity
messages: Belongs to the DnaA family.
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

445932:EMIN RS01590
gene id: 445932:EMIN_RS01590
uniprot id: B2KBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

445932:EMIN RS05115
gene id: 445932:EMIN_RS05115
uniprot id: B2KDF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

445932:EMIN RS05945
gene id: 445932:EMIN_RS05945
uniprot id: B2KDX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

445932:EMIN RS00380
gene id: 445932:EMIN_RS00380
uniprot id: B2KAU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

445932:EMIN RS01750
gene id: 445932:EMIN_RS01750
uniprot id: B2KB80
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05870
gene id: 445932:EMIN_RS05870
uniprot id: B2KDV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

445932:EMIN RS03130
gene id: 445932:EMIN_RS03130
uniprot id: B2KC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

445932:EMIN RS06005
gene id: 445932:EMIN_RS06005
uniprot id: B2KDY4
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS07750
gene id: 445932:EMIN_RS07750
uniprot id: B2KEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

445932:EMIN RS05085
gene id: 445932:EMIN_RS05085
uniprot id: B2KDF1
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS01095
gene id: 445932:EMIN_RS01095
uniprot id: B2KB17
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

445932:EMIN RS07605
gene id: 445932:EMIN_RS07605
uniprot id: B2KEU4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

445932:EMIN RS00330
gene id: 445932:EMIN_RS00330
uniprot id: B2KAT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

445932:EMIN RS03925
gene id: 445932:EMIN_RS03925
uniprot id: B2KCR9
names: Similarity
messages: Belongs to the CapA family.

445932:EMIN RS00430
gene id: 445932:EMIN_RS00430
uniprot id: B2KAV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

445932:EMIN RS05770
gene id: 445932:EMIN_RS05770
uniprot id: B2KDT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

445932:EMIN RS06135
gene id: 445932:EMIN_RS06135
uniprot id: B2KE09
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05560
gene id: 445932:EMIN_RS05560
uniprot id: B2KDP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

445932:EMIN RS07120
gene id: 445932:EMIN_RS07120
uniprot id: B2KEK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

445932:EMIN RS06255
gene id: 445932:EMIN_RS06255
uniprot id: B2KE33
names: Similarity
messages: Belongs to the threonine synthase family.

445932:EMIN RS04515
gene id: 445932:EMIN_RS04515
uniprot id: B2KD41
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05925
gene id: 445932:EMIN_RS05925
uniprot id: B2KDW9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

445932:EMIN RS02260
gene id: 445932:EMIN_RS02260
uniprot id: B2KBH1
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

445932:EMIN RS08455
gene id: 445932:EMIN_RS08455
uniprot id: B2KEH2
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05195
gene id: 445932:EMIN_RS05195
uniprot id: B2KDH3
names: Similarity
messages: Belongs to the thioredoxin family.

445932:EMIN RS03830
gene id: 445932:EMIN_RS03830
uniprot id: B2KCQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

445932:EMIN RS06625
gene id: 445932:EMIN_RS06625
uniprot id: B2KEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

445932:EMIN RS07515
gene id: 445932:EMIN_RS07515
uniprot id: B2KES6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

445932:EMIN RS00065
gene id: 445932:EMIN_RS00065
uniprot id: B2KAN4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

445932:EMIN RS07115
gene id: 445932:EMIN_RS07115
uniprot id: B2KEK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

445932:EMIN RS03705
gene id: 445932:EMIN_RS03705
uniprot id: B2KCM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

445932:EMIN RS07795
gene id: 445932:EMIN_RS07795
uniprot id: B2KEX8
names: Similarity
messages: Belongs to the NDK family.

445932:EMIN RS03860
gene id: 445932:EMIN_RS03860
uniprot id: B2KCQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

445932:EMIN RS03060
gene id: 445932:EMIN_RS03060
uniprot id: B2KC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

445932:EMIN RS01595
gene id: 445932:EMIN_RS01595
uniprot id: B2KBW9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

445932:EMIN RS07675
gene id: 445932:EMIN_RS07675
uniprot id: B2KEV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

445932:EMIN RS05355
gene id: 445932:EMIN_RS05355
uniprot id: B2KDK4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

445932:EMIN RS03765
gene id: 445932:EMIN_RS03765
uniprot id: B2KCN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

445932:EMIN RS05910
gene id: 445932:EMIN_RS05910
uniprot id: B2KDW6
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05790
gene id: 445932:EMIN_RS05790
uniprot id: B2KDU3
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS07310
gene id: 445932:EMIN_RS07310
uniprot id: B2KEP2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

445932:EMIN RS07240
gene id: 445932:EMIN_RS07240
uniprot id: B2KEM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

445932:EMIN RS02570
gene id: 445932:EMIN_RS02570
uniprot id: B2KCD2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

445932:EMIN RS01290
gene id: 445932:EMIN_RS01290
uniprot id: B2KB59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

445932:EMIN RS01970
gene id: 445932:EMIN_RS01970
uniprot id: B2KBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

445932:EMIN RS03105
gene id: 445932:EMIN_RS03105
uniprot id: B2KC30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

445932:EMIN RS04175
gene id: 445932:EMIN_RS04175
uniprot id: B2KCX0
names: Similarity
messages: Belongs to the UPF0597 family.

445932:EMIN RS03740
gene id: 445932:EMIN_RS03740
uniprot id: B2KCN4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

445932:EMIN RS03295
gene id: 445932:EMIN_RS03295
uniprot id: B2KC66
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

445932:EMIN RS01655
gene id: 445932:EMIN_RS01655
uniprot id: B2KBY0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

445932:EMIN RS07140
gene id: 445932:EMIN_RS07140
uniprot id: B2KEK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

445932:EMIN RS03175
gene id: 445932:EMIN_RS03175
uniprot id: B2KC44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

445932:EMIN RS00925
gene id: 445932:EMIN_RS00925
uniprot id: B2KBQ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

445932:EMIN RS03695
gene id: 445932:EMIN_RS03695
uniprot id: B2KCM7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

445932:EMIN RS07920
gene id: 445932:EMIN_RS07920
uniprot id: B2KF01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

445932:EMIN RS07590
gene id: 445932:EMIN_RS07590
uniprot id: B2KEU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

445932:EMIN RS01345
gene id: 445932:EMIN_RS01345
uniprot id: B2KBS5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

445932:EMIN RS00800
gene id: 445932:EMIN_RS00800
uniprot id: B2KBN4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

445932:EMIN RS05150
gene id: 445932:EMIN_RS05150
uniprot id: B2KDG4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

445932:EMIN RS01100
gene id: 445932:EMIN_RS01100
uniprot id: B2KB18
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

445932:EMIN RS07100
gene id: 445932:EMIN_RS07100
uniprot id: B2KEJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

445932:EMIN RS06495
gene id: 445932:EMIN_RS06495
uniprot id: B2KE80
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

445932:EMIN RS03135
gene id: 445932:EMIN_RS03135
uniprot id: B2KC36
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

445932:EMIN RS00700
gene id: 445932:EMIN_RS00700
uniprot id: B2KBL4
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS05775
gene id: 445932:EMIN_RS05775
uniprot id: B2KDU0
names: Subcellular Location Annotation
messages: Membrane

445932:EMIN RS06885
gene id: 445932:EMIN_RS06885
uniprot id: B2KEF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

445932:EMIN RS00110
gene id: 445932:EMIN_RS00110
uniprot id: B2KAP3
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

445932:EMIN RS03675
gene id: 445932:EMIN_RS03675
uniprot id: B2KCM3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

445932:EMIN RS08080
gene id: 445932:EMIN_RS08080
uniprot id: B2KBE8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

445932:EMIN RS01775
gene id: 445932:EMIN_RS01775
uniprot id: B2KB85
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

445932:EMIN RS05990
gene id: 445932:EMIN_RS05990
uniprot id: B2KDY1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

445932:EMIN RS00840
gene id: 445932:EMIN_RS00840
uniprot id: B2KBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

445932:EMIN RS06905
gene id: 445932:EMIN_RS06905
uniprot id: B2KEG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

445932:EMIN RS03955
gene id: 445932:EMIN_RS03955
uniprot id: B2KCS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

445932:EMIN RS05895
gene id: 445932:EMIN_RS05895
uniprot id: B2KDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

445932:EMIN RS00060
gene id: 445932:EMIN_RS00060
uniprot id: B2KAN3
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.