444178:BOV RS12325
gene id: 444178:BOV_RS12325
uniprot id: A0A0H3ASV4
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS01730
gene id: 444178:BOV_RS01730
uniprot id: A0A0H3AQJ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS02270
gene id: 444178:BOV_RS02270
uniprot id: A0A0H3AQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

444178:BOV RS15245
gene id: 444178:BOV_RS15245
uniprot id: A0A0H3AU13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

444178:BOV RS13860
gene id: 444178:BOV_RS13860
uniprot id: A0A0H3ASX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS13285
gene id: 444178:BOV_RS13285
uniprot id: A0A0H3AVI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

444178:BOV RS08125
gene id: 444178:BOV_RS08125
uniprot id: A0A0H3APL9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

444178:BOV RS09855
gene id: 444178:BOV_RS09855
uniprot id: A5VT42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

444178:BOV RS02560
gene id: 444178:BOV_RS02560
uniprot id: A5VP72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

444178:BOV RS05940
gene id: 444178:BOV_RS05940
uniprot id: A5VR08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

444178:BOV RS11600
gene id: 444178:BOV_RS11600
uniprot id: A0A0H3AUF4
names: Similarity
messages: Belongs to the FGGY kinase family.

444178:BOV RS00075
gene id: 444178:BOV_RS00075
uniprot id: A0A0H3AP39
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

444178:BOV RS10195
gene id: 444178:BOV_RS10195
uniprot id: A0A0H3ARH2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

444178:BOV RS10010
gene id: 444178:BOV_RS10010
uniprot id: A0A0H3AQT6
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS03270
gene id: 444178:BOV_RS03270
uniprot id: A0A0H3ARF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

444178:BOV RS02695
gene id: 444178:BOV_RS02695
uniprot id: A0A0H3AQB8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

444178:BOV RS04650
gene id: 444178:BOV_RS04650
uniprot id: A0A0H3AQ95
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

444178:BOV RS11695
gene id: 444178:BOV_RS11695
uniprot id: A0A0H3AUZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

444178:BOV RS04955
gene id: 444178:BOV_RS04955
uniprot id: A5VQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane

444178:BOV RS09320
gene id: 444178:BOV_RS09320
uniprot id: A0A0H3ANN6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

444178:BOV RS11890
gene id: 444178:BOV_RS11890
uniprot id: A0A0H3AQY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS10465
gene id: 444178:BOV_RS10465
uniprot id: A0A0H3ATH4
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS04125
gene id: 444178:BOV_RS04125
uniprot id: A0A0H3ARX1
names: Similarity
messages: Belongs to the BolA/IbaG family.

444178:BOV RS05405
gene id: 444178:BOV_RS05405
uniprot id: A0A0H3AP80
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

444178:BOV RS05825
gene id: 444178:BOV_RS05825
uniprot id: A5VQY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

444178:BOV RS12460
gene id: 444178:BOV_RS12460
uniprot id: A0A0H3ASG9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

444178:BOV RS02190
gene id: 444178:BOV_RS02190
uniprot id: A5VP02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

444178:BOV RS15330
gene id: 444178:BOV_RS15330
uniprot id: A5VVU6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

444178:BOV RS03750
gene id: 444178:BOV_RS03750
uniprot id: A0A0H3APZ3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

444178:BOV RS01990
gene id: 444178:BOV_RS01990
uniprot id: A0A0H3AT36
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

444178:BOV RS09430
gene id: 444178:BOV_RS09430
uniprot id: A0A0H3AS36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

444178:BOV RS14555
gene id: 444178:BOV_RS14555
uniprot id: A0A0H3AT23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS01655
gene id: 444178:BOV_RS01655
uniprot id: A5VNQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

444178:BOV RS06910
gene id: 444178:BOV_RS06910
uniprot id: A0A0H3ATX4
names: Similarity
messages: Belongs to the virb1 family.

444178:BOV RS11350
gene id: 444178:BOV_RS11350
uniprot id: A0A0H3AVQ5
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS02555
gene id: 444178:BOV_RS02555
uniprot id: A0A0H3AM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

444178:BOV RS04815
gene id: 444178:BOV_RS04815
uniprot id: A0A0H3ANK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

444178:BOV RS13500
gene id: 444178:BOV_RS13500
uniprot id: A0A0H3ATA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

444178:BOV RS04455
gene id: 444178:BOV_RS04455
uniprot id: A5VQ81
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

444178:BOV RS10945
gene id: 444178:BOV_RS10945
uniprot id: A0A0H3ATV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

444178:BOV RS13935
gene id: 444178:BOV_RS13935
uniprot id: A0A0H3AV52
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

444178:BOV RS03980
gene id: 444178:BOV_RS03980
uniprot id: A5VPY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

444178:BOV RS03215
gene id: 444178:BOV_RS03215
uniprot id: A0A0H3AR53
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

444178:BOV RS03210
gene id: 444178:BOV_RS03210
uniprot id: A5VPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

444178:BOV RS05210
gene id: 444178:BOV_RS05210
uniprot id: A0A0H3APZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS04605
gene id: 444178:BOV_RS04605
uniprot id: A0A0H3APY9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

444178:BOV RS11960
gene id: 444178:BOV_RS11960
uniprot id: A0A0H3ASE2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

444178:BOV RS05440
gene id: 444178:BOV_RS05440
uniprot id: A5VQQ9
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

444178:BOV RS13480
gene id: 444178:BOV_RS13480
uniprot id: A0A0H3ASD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

444178:BOV RS06635
gene id: 444178:BOV_RS06635
uniprot id: A5VRD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

444178:BOV RS02010
gene id: 444178:BOV_RS02010
uniprot id: A5VNW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

444178:BOV RS09600
gene id: 444178:BOV_RS09600
uniprot id: A0A0H3AR67
names: Similarity
messages: Belongs to the YkuD family.

444178:BOV RS00360
gene id: 444178:BOV_RS00360
uniprot id: A5VN19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

444178:BOV RS07145
gene id: 444178:BOV_RS07145
uniprot id: A0A0H3ASG4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

444178:BOV RS07765
gene id: 444178:BOV_RS07765
uniprot id: A0A0H3APX2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS04270
gene id: 444178:BOV_RS04270
uniprot id: A5VQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

444178:BOV RS02745
gene id: 444178:BOV_RS02745
uniprot id: A0A0H3APL8
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

444178:BOV RS10035
gene id: 444178:BOV_RS10035
uniprot id: A0A0H3AM27
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

444178:BOV RS11290
gene id: 444178:BOV_RS11290
uniprot id: A0A0H3AUW4
names: Similarity
messages: Belongs to the peptidase M16 family.

444178:BOV RS08700
gene id: 444178:BOV_RS08700
uniprot id: A5VSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

444178:BOV RS07365
gene id: 444178:BOV_RS07365
uniprot id: A0A0H3AP25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

444178:BOV RS15290
gene id: 444178:BOV_RS15290
uniprot id: A5VVT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

444178:BOV RS08090
gene id: 444178:BOV_RS08090
uniprot id: A5VS59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

444178:BOV RS12405
gene id: 444178:BOV_RS12405
uniprot id: A0A0H3AV58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS05890
gene id: 444178:BOV_RS05890
uniprot id: A5VQZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

444178:BOV RS04155
gene id: 444178:BOV_RS04155
uniprot id: A5VQ20
names: Similarity
messages: Belongs to the SAICAR synthetase family.

444178:BOV RS10235
gene id: 444178:BOV_RS10235
uniprot id: A5VTB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

444178:BOV RS11025
gene id: 444178:BOV_RS11025
uniprot id: A0A0H3AU71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.

444178:BOV RS06690
gene id: 444178:BOV_RS06690
uniprot id: A0A0H3AQ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

444178:BOV RS07150
gene id: 444178:BOV_RS07150
uniprot id: A0A0H3APF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS05640
gene id: 444178:BOV_RS05640
uniprot id: A0A0H3AR71
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

444178:BOV RS09865
gene id: 444178:BOV_RS09865
uniprot id: A5VT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

444178:BOV RS08400
gene id: 444178:BOV_RS08400
uniprot id: A0A0H3AT87
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

444178:BOV RS08150
gene id: 444178:BOV_RS08150
uniprot id: A5VS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

444178:BOV RS09910
gene id: 444178:BOV_RS09910
uniprot id: A5VT52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

444178:BOV RS04510
gene id: 444178:BOV_RS04510
uniprot id: A0A0H3ARY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

444178:BOV RS03470
gene id: 444178:BOV_RS03470
uniprot id: A0A0H3AP23
names: Similarity
messages: Belongs to the RNase T2 family.

444178:BOV RS11855
gene id: 444178:BOV_RS11855
uniprot id: A0A0H3AT49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

444178:BOV RS06155
gene id: 444178:BOV_RS06155
uniprot id: A5VR48
names: Similarity
messages: Belongs to the SfsA family.

444178:BOV RS01995
gene id: 444178:BOV_RS01995
uniprot id: A5VNW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

444178:BOV RS05745
gene id: 444178:BOV_RS05745
uniprot id: A5VQW7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

444178:BOV RS07490
gene id: 444178:BOV_RS07490
uniprot id: A0A0H3APC0
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS08875
gene id: 444178:BOV_RS08875
uniprot id: A0A0H3AS32
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

444178:BOV RS15400
gene id: 444178:BOV_RS15400
uniprot id: A0A0H3ASM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

444178:BOV RS15305
gene id: 444178:BOV_RS15305
uniprot id: A0A0H3AV41
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

444178:BOV RS10145
gene id: 444178:BOV_RS10145
uniprot id: A0A0H3APJ3
names: Similarity
messages: Belongs to the Dps family.

444178:BOV RS04160
gene id: 444178:BOV_RS04160
uniprot id: A0A0H3AMQ2
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

444178:BOV RS12130
gene id: 444178:BOV_RS12130
uniprot id: A5VU90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane (By similarity).
messages: The complex is composed of two ATP-binding proteins (BOV_A0347 and BOV_A0348), two transmembrane proteins (BOV_A0350 and BOV_A0351) and a solute-binding protein (BOV_A0352).

444178:BOV RS14910
gene id: 444178:BOV_RS14910
uniprot id: A0A0H3AUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

444178:BOV RS08475
gene id: 444178:BOV_RS08475
uniprot id: A5VSD5
names: Function
names: Similarity
names: Subunit
messages: Allows intracellular utilization of 4-hydroxyproline, one of the major constituents of host collagen, by converting 4-hydroxy-L-proline to 4-hydroxy-D-proline, which can be further metabolized by intracellular 4-hydroxy-D-proline oxidases. Strong B-cell mitogen. Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways (By similarity).
messages: Belongs to the proline racemase family.
messages: Homodimer.

444178:BOV RS05435
gene id: 444178:BOV_RS05435
uniprot id: A5VQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

444178:BOV RS08715
gene id: 444178:BOV_RS08715
uniprot id: A5VSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

444178:BOV RS03890
gene id: 444178:BOV_RS03890
uniprot id: A5VPX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.

444178:BOV RS10125
gene id: 444178:BOV_RS10125
uniprot id: A0A0H3ASK7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

444178:BOV RS06965
gene id: 444178:BOV_RS06965
uniprot id: A5VRJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

444178:BOV RS15360
gene id: 444178:BOV_RS15360
uniprot id: A0A0H3ASQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

444178:BOV RS12680
gene id: 444178:BOV_RS12680
uniprot id: A0A0H3ATB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.

444178:BOV RS09840
gene id: 444178:BOV_RS09840
uniprot id: A5VT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

444178:BOV RS06695
gene id: 444178:BOV_RS06695
uniprot id: A0A0H3ARM3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

444178:BOV RS08920
gene id: 444178:BOV_RS08920
uniprot id: A5VSL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

444178:BOV RS05815
gene id: 444178:BOV_RS05815
uniprot id: A5VQY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

444178:BOV RS01795
gene id: 444178:BOV_RS01795
uniprot id: A0A0H3AQW1
names: Function
messages: Multidrug efflux pump.

444178:BOV RS03095
gene id: 444178:BOV_RS03095
uniprot id: A0A0H3ASL9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

444178:BOV RS13115
gene id: 444178:BOV_RS13115
uniprot id: A0A0H3AV09
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

444178:BOV RS05895
gene id: 444178:BOV_RS05895
uniprot id: A5VQZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

444178:BOV RS07630
gene id: 444178:BOV_RS07630
uniprot id: A5VRX4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn regulates CtrA, a transcriptional regulator of the minB operon. The asymmetrical localization of this protein is probably required for cells to enter a new division cycle (By similarity).
messages: Interacts with DivK.

444178:BOV RS13820
gene id: 444178:BOV_RS13820
uniprot id: A5VV34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BA14k family.
messages: Cell membrane
messages: Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport (By similarity).

444178:BOV RS05795
gene id: 444178:BOV_RS05795
uniprot id: A0A0H3AQD5
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

444178:BOV RS11495
gene id: 444178:BOV_RS11495
uniprot id: A0A0H3AVA1
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS13355
gene id: 444178:BOV_RS13355
uniprot id: A0A0H3AUK4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

444178:BOV RS13780
gene id: 444178:BOV_RS13780
uniprot id: A0A0H3AUI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

444178:BOV RS06930
gene id: 444178:BOV_RS06930
uniprot id: A0A0H3ANE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

444178:BOV RS08540
gene id: 444178:BOV_RS08540
uniprot id: A5VSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

444178:BOV RS00850
gene id: 444178:BOV_RS00850
uniprot id: A0A0H3AQ27
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

444178:BOV RS06860
gene id: 444178:BOV_RS06860
uniprot id: A5VRH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

444178:BOV RS04760
gene id: 444178:BOV_RS04760
uniprot id: A0A0H3APG7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

444178:BOV RS15210
gene id: 444178:BOV_RS15210
uniprot id: A0A0H3ATT0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS06810
gene id: 444178:BOV_RS06810
uniprot id: A0A0H3AN65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

444178:BOV RS03910
gene id: 444178:BOV_RS03910
uniprot id: A5VPX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

444178:BOV RS01365
gene id: 444178:BOV_RS01365
uniprot id: A0A0H3ASX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

444178:BOV RS00555
gene id: 444178:BOV_RS00555
uniprot id: A0A0H3AQ85
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

444178:BOV RS02495
gene id: 444178:BOV_RS02495
uniprot id: A0A0H3ANV9
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

444178:BOV RS14150
gene id: 444178:BOV_RS14150
uniprot id: A0A0H3AVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS04935
gene id: 444178:BOV_RS04935
uniprot id: A0A0H3AMY7
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

444178:BOV RS10230
gene id: 444178:BOV_RS10230
uniprot id: A5VTB4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

444178:BOV RS14765
gene id: 444178:BOV_RS14765
uniprot id: A5VVJ6
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

444178:BOV RS00225
gene id: 444178:BOV_RS00225
uniprot id: A0A0H3AS69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

444178:BOV RS12310
gene id: 444178:BOV_RS12310
uniprot id: A5VUC1
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

444178:BOV RS00170
gene id: 444178:BOV_RS00170
uniprot id: A5VMY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

444178:BOV RS06940
gene id: 444178:BOV_RS06940
uniprot id: A0A0H3ASE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

444178:BOV RS14160
gene id: 444178:BOV_RS14160
uniprot id: A0A0H3AV06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

444178:BOV RS02910
gene id: 444178:BOV_RS02910
uniprot id: A0A0H3AR66
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

444178:BOV RS00520
gene id: 444178:BOV_RS00520
uniprot id: A0A0H3AP05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

444178:BOV RS09570
gene id: 444178:BOV_RS09570
uniprot id: A0A0H3AR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

444178:BOV RS07890
gene id: 444178:BOV_RS07890
uniprot id: A5VS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

444178:BOV RS09790
gene id: 444178:BOV_RS09790
uniprot id: A0A0H3APM0
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

444178:BOV RS02355
gene id: 444178:BOV_RS02355
uniprot id: A0A0H3AP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

444178:BOV RS12605
gene id: 444178:BOV_RS12605
uniprot id: A0A0H3ASU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

444178:BOV RS03375
gene id: 444178:BOV_RS03375
uniprot id: A0A0H3ASF3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

444178:BOV RS07350
gene id: 444178:BOV_RS07350
uniprot id: A0A0H3ANX4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

444178:BOV RS10660
gene id: 444178:BOV_RS10660
uniprot id: A0A0H3ATU4
names: Similarity
messages: Belongs to the virb1 family.

444178:BOV RS00960
gene id: 444178:BOV_RS00960
uniprot id: A0A0H3AST8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS04015
gene id: 444178:BOV_RS04015
uniprot id: A5VPZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

444178:BOV RS04870
gene id: 444178:BOV_RS04870
uniprot id: A5VQF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

444178:BOV RS09135
gene id: 444178:BOV_RS09135
uniprot id: A5VSR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

444178:BOV RS05860
gene id: 444178:BOV_RS05860
uniprot id: A5VQZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

444178:BOV RS00415
gene id: 444178:BOV_RS00415
uniprot id: A0A0H3ASU0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS01010
gene id: 444178:BOV_RS01010
uniprot id: A5VNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

444178:BOV RS09735
gene id: 444178:BOV_RS09735
uniprot id: A5VT19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

444178:BOV RS12115
gene id: 444178:BOV_RS12115
uniprot id: A5VU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system (By similarity).
messages: The complex is composed of two ATP-binding proteins (BOV_A0347 and BOV_A0348), two transmembrane proteins (BOV_A0350 and BOV_A0351) and a solute-binding protein (BOV_A0352).

444178:BOV RS11345
gene id: 444178:BOV_RS11345
uniprot id: A5VTW1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

444178:BOV RS05235
gene id: 444178:BOV_RS05235
uniprot id: A0A0H3ARE5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS04225
gene id: 444178:BOV_RS04225
uniprot id: A0A0H3AR31
names: Similarity
messages: Belongs to the aldose epimerase family.

444178:BOV RS13940
gene id: 444178:BOV_RS13940
uniprot id: A5VV55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

444178:BOV RS05185
gene id: 444178:BOV_RS05185
uniprot id: A0A0H3ARL2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS08990
gene id: 444178:BOV_RS08990
uniprot id: A0A0H3ANH9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

444178:BOV RS03090
gene id: 444178:BOV_RS03090
uniprot id: A0A0H3APS3
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS09010
gene id: 444178:BOV_RS09010
uniprot id: A5VSN4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

444178:BOV RS06790
gene id: 444178:BOV_RS06790
uniprot id: A0A0H3AP48
names: Similarity
messages: Belongs to the peptidase M24B family.

444178:BOV RS05800
gene id: 444178:BOV_RS05800
uniprot id: A0A0H3AT15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

444178:BOV RS14670
gene id: 444178:BOV_RS14670
uniprot id: A5VVH9
names: Similarity
messages: Belongs to the UPF0309 family.

444178:BOV RS09940
gene id: 444178:BOV_RS09940
uniprot id: A0A0H3ARK2
names: Similarity
messages: Belongs to the thioredoxin family.

444178:BOV RS05550
gene id: 444178:BOV_RS05550
uniprot id: A0A0H3APY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

444178:BOV RS10415
gene id: 444178:BOV_RS10415
uniprot id: A0A0H3AVE0
names: Similarity
messages: Belongs to the isochorismate synthase family.

444178:BOV RS11305
gene id: 444178:BOV_RS11305
uniprot id: A0A0H3AW21
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

444178:BOV RS13425
gene id: 444178:BOV_RS13425
uniprot id: A0A0H3ARF3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

444178:BOV RS10120
gene id: 444178:BOV_RS10120
uniprot id: A0A0H3ANS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

444178:BOV RS00760
gene id: 444178:BOV_RS00760
uniprot id: A0A0H3AMT6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

444178:BOV RS03245
gene id: 444178:BOV_RS03245
uniprot id: A0A0H3AR42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

444178:BOV RS13850
gene id: 444178:BOV_RS13850
uniprot id: A0A0H3ATH1
names: Similarity
messages: Belongs to the DSD1 family.

444178:BOV RS09780
gene id: 444178:BOV_RS09780
uniprot id: A5VT27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

444178:BOV RS10525
gene id: 444178:BOV_RS10525
uniprot id: A0A0H3AU40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane
messages: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase.

444178:BOV RS03785
gene id: 444178:BOV_RS03785
uniprot id: A0A0H3AQP5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

444178:BOV RS02215
gene id: 444178:BOV_RS02215
uniprot id: A0A0H3ASX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

444178:BOV RS12635
gene id: 444178:BOV_RS12635
uniprot id: A0A0H3AW74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS14480
gene id: 444178:BOV_RS14480
uniprot id: A0A0H3ATF9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

444178:BOV RS15610
gene id: 444178:BOV_RS15610
uniprot id: A0A0H3AWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

444178:BOV RS02290
gene id: 444178:BOV_RS02290
uniprot id: A0A0H3AQC0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

444178:BOV RS10255
gene id: 444178:BOV_RS10255
uniprot id: A0A0H3AN86
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

444178:BOV RS00910
gene id: 444178:BOV_RS00910
uniprot id: A5VNC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

444178:BOV RS07515
gene id: 444178:BOV_RS07515
uniprot id: A0A0H3ANT3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS14875
gene id: 444178:BOV_RS14875
uniprot id: A0A0H3AT28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS13785
gene id: 444178:BOV_RS13785
uniprot id: A0A0H3ARW9
names: Similarity
messages: Belongs to the GcvT family.

444178:BOV RS06800
gene id: 444178:BOV_RS06800
uniprot id: A5VRG5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

444178:BOV RS14190
gene id: 444178:BOV_RS14190
uniprot id: A0A0H3ATU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

444178:BOV RS02055
gene id: 444178:BOV_RS02055
uniprot id: A5VNX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

444178:BOV RS05480
gene id: 444178:BOV_RS05480
uniprot id: A0A0H3ANW2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

444178:BOV RS14135
gene id: 444178:BOV_RS14135
uniprot id: A0A0H3AWE9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

444178:BOV RS09535
gene id: 444178:BOV_RS09535
uniprot id: A0A0H3ASJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

444178:BOV RS07315
gene id: 444178:BOV_RS07315
uniprot id: A5VRR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

444178:BOV RS15070
gene id: 444178:BOV_RS15070
uniprot id: A0A0H3AUX3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

444178:BOV RS14340
gene id: 444178:BOV_RS14340
uniprot id: A0A0H3AVF9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

444178:BOV RS04780
gene id: 444178:BOV_RS04780
uniprot id: A0A0H3AMS6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

444178:BOV RS05290
gene id: 444178:BOV_RS05290
uniprot id: A0A0H3AQA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

444178:BOV RS10865
gene id: 444178:BOV_RS10865
uniprot id: A0A0H3ARA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS04645
gene id: 444178:BOV_RS04645
uniprot id: A0A0H3ANL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

444178:BOV RS13610
gene id: 444178:BOV_RS13610
uniprot id: A0A0H3AT90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS09055
gene id: 444178:BOV_RS09055
uniprot id: A0A0H3AP36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

444178:BOV RS09005
gene id: 444178:BOV_RS09005
uniprot id: A5VSN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

444178:BOV RS12665
gene id: 444178:BOV_RS12665
uniprot id: A0A0H3AS44
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

444178:BOV RS00245
gene id: 444178:BOV_RS00245
uniprot id: A0A0H3APA1
names: Similarity
messages: Belongs to the YkuD family.

444178:BOV RS15295
gene id: 444178:BOV_RS15295
uniprot id: A5VVU0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

444178:BOV RS11935
gene id: 444178:BOV_RS11935
uniprot id: A0A0H3ARQ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS09050
gene id: 444178:BOV_RS09050
uniprot id: A5VSP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

444178:BOV RS14215
gene id: 444178:BOV_RS14215
uniprot id: A0A0H3AU10
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

444178:BOV RS12565
gene id: 444178:BOV_RS12565
uniprot id: A0A0H3ASG5
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS02525
gene id: 444178:BOV_RS02525
uniprot id: A0A0H3AQY2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

444178:BOV RS07460
gene id: 444178:BOV_RS07460
uniprot id: A0A0H3ASR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

444178:BOV RS02830
gene id: 444178:BOV_RS02830
uniprot id: A0A0H3AP46
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

444178:BOV RS10185
gene id: 444178:BOV_RS10185
uniprot id: A0A0H3ARV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS06450
gene id: 444178:BOV_RS06450
uniprot id: A0A0H3AMN7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS13595
gene id: 444178:BOV_RS13595
uniprot id: A5VUZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

444178:BOV RS07200
gene id: 444178:BOV_RS07200
uniprot id: A0A0H3AQZ6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

444178:BOV RS03830
gene id: 444178:BOV_RS03830
uniprot id: A5VPV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

444178:BOV RS00130
gene id: 444178:BOV_RS00130
uniprot id: A0A0H3AT76
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

444178:BOV RS04025
gene id: 444178:BOV_RS04025
uniprot id: A5VPZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

444178:BOV RS12860
gene id: 444178:BOV_RS12860
uniprot id: A0A0H3ASR1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

444178:BOV RS11255
gene id: 444178:BOV_RS11255
uniprot id: A0A0H3AW96
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

444178:BOV RS09245
gene id: 444178:BOV_RS09245
uniprot id: A0A0H3ART1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS11010
gene id: 444178:BOV_RS11010
uniprot id: A0A0H3AQZ5
names: Similarity
messages: Belongs to the hyi family.

444178:BOV RS08965
gene id: 444178:BOV_RS08965
uniprot id: A0A0H3AR98
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

444178:BOV RS14570
gene id: 444178:BOV_RS14570
uniprot id: A0A0H3AUL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS06315
gene id: 444178:BOV_RS06315
uniprot id: A0A0H3AP66
names: Similarity
messages: Belongs to the HIBADH-related family.

444178:BOV RS06590
gene id: 444178:BOV_RS06590
uniprot id: A0A0H3ARS6
names: Similarity
messages: Belongs to the PhzF family.

444178:BOV RS00765
gene id: 444178:BOV_RS00765
uniprot id: A0A0H3ANR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

444178:BOV RS05380
gene id: 444178:BOV_RS05380
uniprot id: A5VQP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

444178:BOV RS08160
gene id: 444178:BOV_RS08160
uniprot id: A0A0H3AT92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

444178:BOV RS11770
gene id: 444178:BOV_RS11770
uniprot id: A0A0H3ATJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS00890
gene id: 444178:BOV_RS00890
uniprot id: A0A0H3ANV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BA14k family.
messages: Cell membrane
messages: Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.
messages: Membrane

444178:BOV RS10225
gene id: 444178:BOV_RS10225
uniprot id: A5VTB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

444178:BOV RS14735
gene id: 444178:BOV_RS14735
uniprot id: A5VVJ0
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

444178:BOV RS08720
gene id: 444178:BOV_RS08720
uniprot id: A5VSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

444178:BOV RS05525
gene id: 444178:BOV_RS05525
uniprot id: A5VQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

444178:BOV RS01805
gene id: 444178:BOV_RS01805
uniprot id: A0A0H3AP81
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS10625
gene id: 444178:BOV_RS10625
uniprot id: A0A0H3AV82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the virB8 family.
messages: Membrane

444178:BOV RS06900
gene id: 444178:BOV_RS06900
uniprot id: A5VRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

444178:BOV RS01780
gene id: 444178:BOV_RS01780
uniprot id: A0A0H3AR54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS09440
gene id: 444178:BOV_RS09440
uniprot id: A0A0H3APH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Membrane

444178:BOV RS13810
gene id: 444178:BOV_RS13810
uniprot id: A0A0H3ASP6
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

444178:BOV RS13265
gene id: 444178:BOV_RS13265
uniprot id: A0A0H3ARA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS05830
gene id: 444178:BOV_RS05830
uniprot id: A0A0H3ANK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

444178:BOV RS11085
gene id: 444178:BOV_RS11085
uniprot id: A0A0H3ATA1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS13375
gene id: 444178:BOV_RS13375
uniprot id: A0A0H3ATG1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

444178:BOV RS02700
gene id: 444178:BOV_RS02700
uniprot id: A0A0H3ANZ2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

444178:BOV RS04030
gene id: 444178:BOV_RS04030
uniprot id: A0A0H3ARI6
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

444178:BOV RS10030
gene id: 444178:BOV_RS10030
uniprot id: A5VT73
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

444178:BOV RS06060
gene id: 444178:BOV_RS06060
uniprot id: A0A0H3ASL3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

444178:BOV RS01905
gene id: 444178:BOV_RS01905
uniprot id: A0A0H3AR12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. FixP subunit is required for transferring electrons from donor cytochrome c via its heme groups to FixO subunit. From there, electrons are shuttled to the catalytic binuclear center of FixN subunit where oxygen reduction takes place. The complex also functions as a proton pump.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase at least composed of FixN, FixO, FixQ and FixP.
messages: Membrane

444178:BOV RS01790
gene id: 444178:BOV_RS01790
uniprot id: A5VNS7
names: Similarity
messages: Belongs to the proline racemase family.

444178:BOV RS04880
gene id: 444178:BOV_RS04880
uniprot id: A0A0H3AMY3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

444178:BOV RS05965
gene id: 444178:BOV_RS05965
uniprot id: A5VR14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

444178:BOV RS06685
gene id: 444178:BOV_RS06685
uniprot id: A0A0H3ANH8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

444178:BOV RS09575
gene id: 444178:BOV_RS09575
uniprot id: A5VSZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

444178:BOV RS13525
gene id: 444178:BOV_RS13525
uniprot id: A0A0H3AUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

444178:BOV RS06620
gene id: 444178:BOV_RS06620
uniprot id: A5VRC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

444178:BOV RS12715
gene id: 444178:BOV_RS12715
uniprot id: A0A0H3AVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

444178:BOV RS13195
gene id: 444178:BOV_RS13195
uniprot id: A5VUS8
names: Similarity
messages: Belongs to the UPF0173 family.

444178:BOV RS05500
gene id: 444178:BOV_RS05500
uniprot id: A5VQR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

444178:BOV RS12765
gene id: 444178:BOV_RS12765
uniprot id: A0A0H3AU60
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

444178:BOV RS07850
gene id: 444178:BOV_RS07850
uniprot id: A5VS09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Monomer.

444178:BOV RS10310
gene id: 444178:BOV_RS10310
uniprot id: A5VTD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

444178:BOV RS11225
gene id: 444178:BOV_RS11225
uniprot id: A0A0H3ATK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

444178:BOV RS02565
gene id: 444178:BOV_RS02565
uniprot id: A0A0H3ANC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

444178:BOV RS10165
gene id: 444178:BOV_RS10165
uniprot id: A5VTA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

444178:BOV RS06185
gene id: 444178:BOV_RS06185
uniprot id: A0A0H3AT45
names: Similarity
messages: Belongs to the CobH/CbiC family.

444178:BOV RS05865
gene id: 444178:BOV_RS05865
uniprot id: A5VQZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

444178:BOV RS02315
gene id: 444178:BOV_RS02315
uniprot id: A5VP26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

444178:BOV RS03780
gene id: 444178:BOV_RS03780
uniprot id: A5VPU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

444178:BOV RS09955
gene id: 444178:BOV_RS09955
uniprot id: A5VT61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

444178:BOV RS10495
gene id: 444178:BOV_RS10495
uniprot id: A0A0H3AWK2
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

444178:BOV RS02000
gene id: 444178:BOV_RS02000
uniprot id: A0A0H3ANH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

444178:BOV RS03230
gene id: 444178:BOV_RS03230
uniprot id: A5VPI9
names: Function
names: Similarity
messages: Belongs to the RelA/SpoT family.
messages: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. Plays a role in adaptation of Brucella to its intracellular host environment (By similarity).

444178:BOV RS11100
gene id: 444178:BOV_RS11100
uniprot id: A0A0H3AV93
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

444178:BOV RS06240
gene id: 444178:BOV_RS06240
uniprot id: A5VR64
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

444178:BOV RS10860
gene id: 444178:BOV_RS10860
uniprot id: A0A0H3AUF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

444178:BOV RS13755
gene id: 444178:BOV_RS13755
uniprot id: A0A0H3ASW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS06540
gene id: 444178:BOV_RS06540
uniprot id: A0A0H3ARA1
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00375
gene id: 444178:BOV_RS00375
uniprot id: A5VN22
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

444178:BOV RS05805
gene id: 444178:BOV_RS05805
uniprot id: A5VQY1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

444178:BOV RS13035
gene id: 444178:BOV_RS13035
uniprot id: A0A0H3AU00
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

444178:BOV RS00045
gene id: 444178:BOV_RS00045
uniprot id: A0A0H3ANJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

444178:BOV RS14935
gene id: 444178:BOV_RS14935
uniprot id: A5VVM8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

444178:BOV RS04115
gene id: 444178:BOV_RS04115
uniprot id: A0A0H3APG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS12390
gene id: 444178:BOV_RS12390
uniprot id: A0A0H3AUG7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS04565
gene id: 444178:BOV_RS04565
uniprot id: A0A0H3ATI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS02390
gene id: 444178:BOV_RS02390
uniprot id: A5VP42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

444178:BOV RS10300
gene id: 444178:BOV_RS10300
uniprot id: A0A0H3APW1
names: Similarity
messages: Belongs to the peptidase M17 family.

444178:BOV RS04885
gene id: 444178:BOV_RS04885
uniprot id: A0A0H3AP82
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

444178:BOV RS08855
gene id: 444178:BOV_RS08855
uniprot id: A5VSK3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

444178:BOV RS11860
gene id: 444178:BOV_RS11860
uniprot id: A0A0H3AUP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

444178:BOV RS05245
gene id: 444178:BOV_RS05245
uniprot id: A0A0H3API8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

444178:BOV RS16045
gene id: 444178:BOV_RS16045
uniprot id: A0A0H3AMM8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

444178:BOV RS13775
gene id: 444178:BOV_RS13775
uniprot id: A5VV25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

444178:BOV RS14920
gene id: 444178:BOV_RS14920
uniprot id: A0A0H3AV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS12690
gene id: 444178:BOV_RS12690
uniprot id: A0A0H3ASE7
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS10090
gene id: 444178:BOV_RS10090
uniprot id: A0A0H3AP61
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

444178:BOV RS13660
gene id: 444178:BOV_RS13660
uniprot id: A0A0H3AQN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

444178:BOV RS00175
gene id: 444178:BOV_RS00175
uniprot id: A0A0H3AQC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

444178:BOV RS15865
gene id: 444178:BOV_RS15865
uniprot id: A0A0H3ASS4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

444178:BOV RS14110
gene id: 444178:BOV_RS14110
uniprot id: A0A0H3AUQ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

444178:BOV RS03985
gene id: 444178:BOV_RS03985
uniprot id: A5VPY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

444178:BOV RS04850
gene id: 444178:BOV_RS04850
uniprot id: A0A0H3AQX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

444178:BOV RS14240
gene id: 444178:BOV_RS14240
uniprot id: A0A0H3AUB9
names: Similarity
messages: Belongs to the UPF0166 family.

444178:BOV RS14915
gene id: 444178:BOV_RS14915
uniprot id: A0A0H3ATT6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS04940
gene id: 444178:BOV_RS04940
uniprot id: A0A0H3ALX4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

444178:BOV RS12645
gene id: 444178:BOV_RS12645
uniprot id: A0A0H3AUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS13165
gene id: 444178:BOV_RS13165
uniprot id: A0A0H3AV66
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

444178:BOV RS08085
gene id: 444178:BOV_RS08085
uniprot id: A5VS58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

444178:BOV RS15190
gene id: 444178:BOV_RS15190
uniprot id: A0A0H3AUQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane.

444178:BOV RS10405
gene id: 444178:BOV_RS10405
uniprot id: A0A0H3AVX8
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

444178:BOV RS15280
gene id: 444178:BOV_RS15280
uniprot id: A5VVT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

444178:BOV RS15370
gene id: 444178:BOV_RS15370
uniprot id: A0A0H3ASZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

444178:BOV RS12330
gene id: 444178:BOV_RS12330
uniprot id: A0A0H3AV31
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

444178:BOV RS11205
gene id: 444178:BOV_RS11205
uniprot id: A5VTT5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

444178:BOV RS14960
gene id: 444178:BOV_RS14960
uniprot id: A0A0H3ATF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

444178:BOV RS02510
gene id: 444178:BOV_RS02510
uniprot id: A0A0H3ARN3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

444178:BOV RS04775
gene id: 444178:BOV_RS04775
uniprot id: A0A0H3APY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

444178:BOV RS05555
gene id: 444178:BOV_RS05555
uniprot id: A5VQT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

444178:BOV RS11800
gene id: 444178:BOV_RS11800
uniprot id: A0A0H3AUQ2
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS10260
gene id: 444178:BOV_RS10260
uniprot id: A5VTB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

444178:BOV RS07845
gene id: 444178:BOV_RS07845
uniprot id: A0A0H3AP13
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

444178:BOV RS14575
gene id: 444178:BOV_RS14575
uniprot id: A5VVG4
names: Similarity
messages: Belongs to the UPF0434 family.

444178:BOV RS12600
gene id: 444178:BOV_RS12600
uniprot id: A0A0H3AVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS04310
gene id: 444178:BOV_RS04310
uniprot id: A0A0H3APD2
names: Similarity
messages: Belongs to the HesB/IscA family.

444178:BOV RS11910
gene id: 444178:BOV_RS11910
uniprot id: A0A0H3ATC8
names: Function
names: Similarity
messages: Belongs to the group II decarboxylase family.
messages: Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria.

444178:BOV RS12900
gene id: 444178:BOV_RS12900
uniprot id: A0A0H3AVJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane.

444178:BOV RS01375
gene id: 444178:BOV_RS01375
uniprot id: A5VNK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

444178:BOV RS14505
gene id: 444178:BOV_RS14505
uniprot id: A0A0H3AVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

444178:BOV RS11820
gene id: 444178:BOV_RS11820
uniprot id: A0A0H3AUY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

444178:BOV RS13560
gene id: 444178:BOV_RS13560
uniprot id: A0A0H3ARU3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS09370
gene id: 444178:BOV_RS09370
uniprot id: A0A0H3ANR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

444178:BOV RS01495
gene id: 444178:BOV_RS01495
uniprot id: A0A0H3AQK0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

444178:BOV RS05920
gene id: 444178:BOV_RS05920
uniprot id: A5VR04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

444178:BOV RS12570
gene id: 444178:BOV_RS12570
uniprot id: A0A0H3AR92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

444178:BOV RS15815
gene id: 444178:BOV_RS15815
uniprot id: A0A0H3AU98
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS15050
gene id: 444178:BOV_RS15050
uniprot id: A0A0H3AUU0
names: Similarity
messages: Belongs to the creatininase superfamily.

444178:BOV RS03265
gene id: 444178:BOV_RS03265
uniprot id: A5VPJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

444178:BOV RS13890
gene id: 444178:BOV_RS13890
uniprot id: A0A0H3ASZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

444178:BOV RS07605
gene id: 444178:BOV_RS07605
uniprot id: A0A0H3AN40
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

444178:BOV RS14165
gene id: 444178:BOV_RS14165
uniprot id: A5VV94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

444178:BOV RS02155
gene id: 444178:BOV_RS02155
uniprot id: A0A0H3AT30
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

444178:BOV RS02575
gene id: 444178:BOV_RS02575
uniprot id: A0A0H3ANX1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

444178:BOV RS06120
gene id: 444178:BOV_RS06120
uniprot id: A0A0H3AQ84
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

444178:BOV RS12745
gene id: 444178:BOV_RS12745
uniprot id: A0A0H3ASR6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

444178:BOV RS09520
gene id: 444178:BOV_RS09520
uniprot id: A5VSY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

444178:BOV RS00680
gene id: 444178:BOV_RS00680
uniprot id: A0A0H3ANE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS12430
gene id: 444178:BOV_RS12430
uniprot id: A0A0H3ATV2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

444178:BOV RS05345
gene id: 444178:BOV_RS05345
uniprot id: A0A0H3ATW5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

444178:BOV RS10385
gene id: 444178:BOV_RS10385
uniprot id: A0A0H3AVC7
names: Similarity
messages: Belongs to the BMP lipoprotein family.

444178:BOV RS03740
gene id: 444178:BOV_RS03740
uniprot id: A5VPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

444178:BOV RS03080
gene id: 444178:BOV_RS03080
uniprot id: A0A0H3AND1
names: Similarity
messages: Belongs to the peptidase M1 family.

444178:BOV RS05765
gene id: 444178:BOV_RS05765
uniprot id: A0A0H3ASH0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

444178:BOV RS15720
gene id: 444178:BOV_RS15720
uniprot id: A0A0H3AT22
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

444178:BOV RS02040
gene id: 444178:BOV_RS02040
uniprot id: A0A0H3AR81
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

444178:BOV RS03845
gene id: 444178:BOV_RS03845
uniprot id: A0A0H3APN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

444178:BOV RS12305
gene id: 444178:BOV_RS12305
uniprot id: A0A0H3AUH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

444178:BOV RS08275
gene id: 444178:BOV_RS08275
uniprot id: A5VS98
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

444178:BOV RS08980
gene id: 444178:BOV_RS08980
uniprot id: A0A0H3ARB8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

444178:BOV RS13240
gene id: 444178:BOV_RS13240
uniprot id: A0A0H3AUN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

444178:BOV RS12490
gene id: 444178:BOV_RS12490
uniprot id: A0A0H3ATE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS06365
gene id: 444178:BOV_RS06365
uniprot id: A0A0H3ANR9
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS03520
gene id: 444178:BOV_RS03520
uniprot id: A0A0H3ASD1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

444178:BOV RS05530
gene id: 444178:BOV_RS05530
uniprot id: A5VQS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

444178:BOV RS01045
gene id: 444178:BOV_RS01045
uniprot id: A0A0H3AQ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS11335
gene id: 444178:BOV_RS11335
uniprot id: A5VTV9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

444178:BOV RS08095
gene id: 444178:BOV_RS08095
uniprot id: A5VS60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

444178:BOV RS07905
gene id: 444178:BOV_RS07905
uniprot id: A0A0H3AN70
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

444178:BOV RS00465
gene id: 444178:BOV_RS00465
uniprot id: A0A0H3AQT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

444178:BOV RS08570
gene id: 444178:BOV_RS08570
uniprot id: A5VSF5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

444178:BOV RS10395
gene id: 444178:BOV_RS10395
uniprot id: A0A0H3AVL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

444178:BOV RS15635
gene id: 444178:BOV_RS15635
uniprot id: A0A0H3AUH4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

444178:BOV RS14585
gene id: 444178:BOV_RS14585
uniprot id: A0A0H3AV56
names: Similarity
messages: Belongs to the thioredoxin family.

444178:BOV RS07595
gene id: 444178:BOV_RS07595
uniprot id: A5VRW9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes.

444178:BOV RS15600
gene id: 444178:BOV_RS15600
uniprot id: A0A0H3ATW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

444178:BOV RS05900
gene id: 444178:BOV_RS05900
uniprot id: A5VR00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

444178:BOV RS12185
gene id: 444178:BOV_RS12185
uniprot id: A0A0H3AW26
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS06845
gene id: 444178:BOV_RS06845
uniprot id: A0A0H3APB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

444178:BOV RS15645
gene id: 444178:BOV_RS15645
uniprot id: A5VW00
names: Caution
names: Function
names: Miscellaneous
messages: Lacks the conserved Asp residue in position 50 usually required for phosphorylation.
messages: Required for transcription of flagellar genes.
messages: There is no cognate histidine kinase partner identified so far for FtcR.

444178:BOV RS07280
gene id: 444178:BOV_RS07280
uniprot id: A0A0H3AQ23
names: Subcellular Location Annotation
messages: Mitochondrion

444178:BOV RS05270
gene id: 444178:BOV_RS05270
uniprot id: A0A0H3ALU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS01930
gene id: 444178:BOV_RS01930
uniprot id: A0A0H3APB9
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

444178:BOV RS09360
gene id: 444178:BOV_RS09360
uniprot id: A0A0H3ASP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

444178:BOV RS15325
gene id: 444178:BOV_RS15325
uniprot id: A0A0H3AVX0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

444178:BOV RS05080
gene id: 444178:BOV_RS05080
uniprot id: A0A0H3AP64
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS02295
gene id: 444178:BOV_RS02295
uniprot id: A0A0H3AS30
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

444178:BOV RS10075
gene id: 444178:BOV_RS10075
uniprot id: A0A0H3ATS7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

444178:BOV RS04920
gene id: 444178:BOV_RS04920
uniprot id: A0A0H3AN74
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

444178:BOV RS07535
gene id: 444178:BOV_RS07535
uniprot id: A0A0H3APK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

444178:BOV RS08870
gene id: 444178:BOV_RS08870
uniprot id: A0A0H3ASC4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

444178:BOV RS06560
gene id: 444178:BOV_RS06560
uniprot id: A0A0H3APQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

444178:BOV RS04080
gene id: 444178:BOV_RS04080
uniprot id: A0A0H3AR65
names: Subcellular Location Annotation
messages: Cytoplasm

444178:BOV RS02115
gene id: 444178:BOV_RS02115
uniprot id: A0A0H3ARX0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

444178:BOV RS08080
gene id: 444178:BOV_RS08080
uniprot id: A0A0H3AN38
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

444178:BOV RS01340
gene id: 444178:BOV_RS01340
uniprot id: A0A0H3AS04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

444178:BOV RS05215
gene id: 444178:BOV_RS05215
uniprot id: A0A0H3ANL6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

444178:BOV RS05905
gene id: 444178:BOV_RS05905
uniprot id: A0A0H3ASS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

444178:BOV RS05320
gene id: 444178:BOV_RS05320
uniprot id: A5VQN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

444178:BOV RS03420
gene id: 444178:BOV_RS03420
uniprot id: A0A0H3AP45
names: Similarity
messages: Belongs to the DinB family.

444178:BOV RS07160
gene id: 444178:BOV_RS07160
uniprot id: A0A0H3AMW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

444178:BOV RS08015
gene id: 444178:BOV_RS08015
uniprot id: A0A0H3AS46
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

444178:BOV RS03855
gene id: 444178:BOV_RS03855
uniprot id: A0A0H3ARF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

444178:BOV RS02450
gene id: 444178:BOV_RS02450
uniprot id: A0A0H3AQV0
names: Similarity
messages: Belongs to the threonine synthase family.

444178:BOV RS08420
gene id: 444178:BOV_RS08420
uniprot id: A0A0H3AN32
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

444178:BOV RS02085
gene id: 444178:BOV_RS02085
uniprot id: A0A0H3AQR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

444178:BOV RS03280
gene id: 444178:BOV_RS03280
uniprot id: A0A0H3AS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

444178:BOV RS02530
gene id: 444178:BOV_RS02530
uniprot id: A0A0H3AT31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

444178:BOV RS06755
gene id: 444178:BOV_RS06755
uniprot id: A5VRF8
names: Similarity
messages: Belongs to the UPF0303 family.

444178:BOV RS13450
gene id: 444178:BOV_RS13450
uniprot id: A0A0H3AVD4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS12410
gene id: 444178:BOV_RS12410
uniprot id: A0A0H3AV16
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS05250
gene id: 444178:BOV_RS05250
uniprot id: A0A0H3ANU3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

444178:BOV RS14560
gene id: 444178:BOV_RS14560
uniprot id: A0A0H3AT97
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS02135
gene id: 444178:BOV_RS02135
uniprot id: A0A0H3AM58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

444178:BOV RS01480
gene id: 444178:BOV_RS01480
uniprot id: A0A0H3ASN5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

444178:BOV RS03285
gene id: 444178:BOV_RS03285
uniprot id: A0A0H3AQU2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

444178:BOV RS11640
gene id: 444178:BOV_RS11640
uniprot id: A0A0H3AV14
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS04185
gene id: 444178:BOV_RS04185
uniprot id: A0A0H3AND3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

444178:BOV RS08075
gene id: 444178:BOV_RS08075
uniprot id: A0A0H3ASY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

444178:BOV RS08970
gene id: 444178:BOV_RS08970
uniprot id: A0A0H3ANX8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

444178:BOV RS03395
gene id: 444178:BOV_RS03395
uniprot id: A0A0H3ANI0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

444178:BOV RS14745
gene id: 444178:BOV_RS14745
uniprot id: A0A0H3AQT1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

444178:BOV RS05455
gene id: 444178:BOV_RS05455
uniprot id: A0A0H3AQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

444178:BOV RS12035
gene id: 444178:BOV_RS12035
uniprot id: A0A0H3ATT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

444178:BOV RS05880
gene id: 444178:BOV_RS05880
uniprot id: A5VQZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

444178:BOV RS10370
gene id: 444178:BOV_RS10370
uniprot id: A0A0H3ASN3
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS04315
gene id: 444178:BOV_RS04315
uniprot id: A5VQ53
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

444178:BOV RS02720
gene id: 444178:BOV_RS02720
uniprot id: A0A0H3AT42
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS02430
gene id: 444178:BOV_RS02430
uniprot id: A5VP50
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

444178:BOV RS08445
gene id: 444178:BOV_RS08445
uniprot id: A0A0H3ARP1
names: Function
names: Similarity
messages: Belongs to the leucine-binding protein family.
messages: Component of an amino-acid transport system.

444178:BOV RS09300
gene id: 444178:BOV_RS09300
uniprot id: A0A0H3AQC3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

444178:BOV RS06405
gene id: 444178:BOV_RS06405
uniprot id: A0A0H3ATR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

444178:BOV RS05115
gene id: 444178:BOV_RS05115
uniprot id: A0A0H3AN29
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

444178:BOV RS13200
gene id: 444178:BOV_RS13200
uniprot id: A5VUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

444178:BOV RS05470
gene id: 444178:BOV_RS05470
uniprot id: A5VQR5
names: Similarity
messages: Belongs to the TrpC family.

444178:BOV RS03200
gene id: 444178:BOV_RS03200
uniprot id: A0A0H3AS63
names: Similarity
messages: Belongs to the virb1 family.

444178:BOV RS04585
gene id: 444178:BOV_RS04585
uniprot id: A0A0H3AP12
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

444178:BOV RS06700
gene id: 444178:BOV_RS06700
uniprot id: A5VRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS02230
gene id: 444178:BOV_RS02230
uniprot id: A5VP09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

444178:BOV RS09950
gene id: 444178:BOV_RS09950
uniprot id: A5VT60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

444178:BOV RS00830
gene id: 444178:BOV_RS00830
uniprot id: A0A0H3ASJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

444178:BOV RS04010
gene id: 444178:BOV_RS04010
uniprot id: A5VPZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

444178:BOV RS04700
gene id: 444178:BOV_RS04700
uniprot id: A5VQC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

444178:BOV RS07355
gene id: 444178:BOV_RS07355
uniprot id: A0A0H3ARD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

444178:BOV RS08625
gene id: 444178:BOV_RS08625
uniprot id: A0A0H3AQ48
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

444178:BOV RS14895
gene id: 444178:BOV_RS14895
uniprot id: A0A0H3AUG4
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00405
gene id: 444178:BOV_RS00405
uniprot id: A0A0H3APA8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

444178:BOV RS01820
gene id: 444178:BOV_RS01820
uniprot id: A0A0H3ANN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

444178:BOV RS09775
gene id: 444178:BOV_RS09775
uniprot id: A0A0H3AP28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

444178:BOV RS04365
gene id: 444178:BOV_RS04365
uniprot id: A5VQ63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

444178:BOV RS11745
gene id: 444178:BOV_RS11745
uniprot id: A0A0H3AUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

444178:BOV RS00215
gene id: 444178:BOV_RS00215
uniprot id: A0A0H3AR27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

444178:BOV RS08575
gene id: 444178:BOV_RS08575
uniprot id: A0A0H3AQF1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS05375
gene id: 444178:BOV_RS05375
uniprot id: A0A0H3ARL8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

444178:BOV RS03225
gene id: 444178:BOV_RS03225
uniprot id: A5VPI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

444178:BOV RS05450
gene id: 444178:BOV_RS05450
uniprot id: A0A0H3AR99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

444178:BOV RS02420
gene id: 444178:BOV_RS02420
uniprot id: A0A0H3APJ2
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

444178:BOV RS03715
gene id: 444178:BOV_RS03715
uniprot id: A5VPT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS06865
gene id: 444178:BOV_RS06865
uniprot id: A0A0H3AR60
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS05915
gene id: 444178:BOV_RS05915
uniprot id: A5VR03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

444178:BOV RS11040
gene id: 444178:BOV_RS11040
uniprot id: A0A0H3ASJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

444178:BOV RS04835
gene id: 444178:BOV_RS04835
uniprot id: A0A0H3APF0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

444178:BOV RS11070
gene id: 444178:BOV_RS11070
uniprot id: A0A0H3AVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

444178:BOV RS03460
gene id: 444178:BOV_RS03460
uniprot id: Q45335
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Omp25/RopB family.
messages: Cell outer membrane
messages: Has a C-terminal deletion compared to that of other Brucella species.

444178:BOV RS09310
gene id: 444178:BOV_RS09310
uniprot id: A0A0H3ASS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

444178:BOV RS09340
gene id: 444178:BOV_RS09340
uniprot id: A5VSU9
names: Similarity
messages: Belongs to the UPF0178 family.

444178:BOV RS07830
gene id: 444178:BOV_RS07830
uniprot id: A0A0H3AQZ1
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00325
gene id: 444178:BOV_RS00325
uniprot id: A0A0H3APE5
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS15740
gene id: 444178:BOV_RS15740
uniprot id: A0A0H3AVM8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS00035
gene id: 444178:BOV_RS00035
uniprot id: A0A0H3ARK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

444178:BOV RS12890
gene id: 444178:BOV_RS12890
uniprot id: A0A0H3AU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system.

444178:BOV RS14610
gene id: 444178:BOV_RS14610
uniprot id: A0A0H3AUN4
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family.

444178:BOV RS12055
gene id: 444178:BOV_RS12055
uniprot id: A0A0H3AQV7
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS09635
gene id: 444178:BOV_RS09635
uniprot id: A0A0H3AP07
names: Similarity
messages: Belongs to the Gfa family.

444178:BOV RS06495
gene id: 444178:BOV_RS06495
uniprot id: A0A0H3AM67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

444178:BOV RS11260
gene id: 444178:BOV_RS11260
uniprot id: A0A0H3AU65
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

444178:BOV RS05175
gene id: 444178:BOV_RS05175
uniprot id: A5VQL0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

444178:BOV RS14000
gene id: 444178:BOV_RS14000
uniprot id: A0A0H3AQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

444178:BOV RS06125
gene id: 444178:BOV_RS06125
uniprot id: A0A0H3AQ73
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

444178:BOV RS06355
gene id: 444178:BOV_RS06355
uniprot id: A0A0H3APZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

444178:BOV RS08120
gene id: 444178:BOV_RS08120
uniprot id: A5VS65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

444178:BOV RS15405
gene id: 444178:BOV_RS15405
uniprot id: A0A0H3AUC8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS15795
gene id: 444178:BOV_RS15795
uniprot id: A0A0H3ATR5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS00470
gene id: 444178:BOV_RS00470
uniprot id: A0A0H3ASB8
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

444178:BOV RS11895
gene id: 444178:BOV_RS11895
uniprot id: A0A0H3AU28
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

444178:BOV RS02995
gene id: 444178:BOV_RS02995
uniprot id: A0A0H3AN68
names: Similarity
messages: Belongs to the peptidase C40 family.

444178:BOV RS15175
gene id: 444178:BOV_RS15175
uniprot id: A0A0H3ATY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system.

444178:BOV RS02765
gene id: 444178:BOV_RS02765
uniprot id: A5VPA6
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

444178:BOV RS02090
gene id: 444178:BOV_RS02090
uniprot id: A0A0H3AP85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

444178:BOV RS03390
gene id: 444178:BOV_RS03390
uniprot id: A0A0H3AQZ4
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS13040
gene id: 444178:BOV_RS13040
uniprot id: A5VUQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

444178:BOV RS09740
gene id: 444178:BOV_RS09740
uniprot id: A5VT20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

444178:BOV RS14435
gene id: 444178:BOV_RS14435
uniprot id: A0A0H3AU23
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS06850
gene id: 444178:BOV_RS06850
uniprot id: A5VRH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

444178:BOV RS13220
gene id: 444178:BOV_RS13220
uniprot id: A5VUT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

444178:BOV RS05355
gene id: 444178:BOV_RS05355
uniprot id: A0A0H3AR24
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

444178:BOV RS10815
gene id: 444178:BOV_RS10815
uniprot id: A0A0H3ATG7
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00920
gene id: 444178:BOV_RS00920
uniprot id: A0A0H3APH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

444178:BOV RS01870
gene id: 444178:BOV_RS01870
uniprot id: A0A0H3AS79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

444178:BOV RS04590
gene id: 444178:BOV_RS04590
uniprot id: A0A0H3APM4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

444178:BOV RS02205
gene id: 444178:BOV_RS02205
uniprot id: A0A0H3APG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

444178:BOV RS09765
gene id: 444178:BOV_RS09765
uniprot id: A5VT24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS09230
gene id: 444178:BOV_RS09230
uniprot id: A0A0H3APM9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS04765
gene id: 444178:BOV_RS04765
uniprot id: A5VQD7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

444178:BOV RS05870
gene id: 444178:BOV_RS05870
uniprot id: A5VQZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

444178:BOV RS04840
gene id: 444178:BOV_RS04840
uniprot id: A0A0H3APQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

444178:BOV RS10880
gene id: 444178:BOV_RS10880
uniprot id: A0A0H3AU15
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS04705
gene id: 444178:BOV_RS04705
uniprot id: A5VQC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

444178:BOV RS08530
gene id: 444178:BOV_RS08530
uniprot id: A5VSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

444178:BOV RS12885
gene id: 444178:BOV_RS12885
uniprot id: A0A0H3AU79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system.

444178:BOV RS15910
gene id: 444178:BOV_RS15910
uniprot id: A0A0H3ATA8
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00600
gene id: 444178:BOV_RS00600
uniprot id: A0A0H3AN53
names: Similarity
messages: Belongs to the DEAD box helicase family.

444178:BOV RS10110
gene id: 444178:BOV_RS10110
uniprot id: A0A0H3AQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS02265
gene id: 444178:BOV_RS02265
uniprot id: A5VP16
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

444178:BOV RS04575
gene id: 444178:BOV_RS04575
uniprot id: A0A0H3AP86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

444178:BOV RS05925
gene id: 444178:BOV_RS05925
uniprot id: A5VR05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

444178:BOV RS03540
gene id: 444178:BOV_RS03540
uniprot id: A0A0H3AN91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

444178:BOV RS03065
gene id: 444178:BOV_RS03065
uniprot id: A0A0H3APP0
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

444178:BOV RS04970
gene id: 444178:BOV_RS04970
uniprot id: A0A0H3AN54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

444178:BOV RS12005
gene id: 444178:BOV_RS12005
uniprot id: A5VU71
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

444178:BOV RS09945
gene id: 444178:BOV_RS09945
uniprot id: A0A0H3AM72
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

444178:BOV RS10220
gene id: 444178:BOV_RS10220
uniprot id: A5VTB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

444178:BOV RS07335
gene id: 444178:BOV_RS07335
uniprot id: A5VRR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS11510
gene id: 444178:BOV_RS11510
uniprot id: A0A0H3AVK7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

444178:BOV RS09115
gene id: 444178:BOV_RS09115
uniprot id: A0A0H3AQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhizobiaceae omp19 lipoprotein family.
messages: Cell outer membrane
messages: Membrane

444178:BOV RS11060
gene id: 444178:BOV_RS11060
uniprot id: A0A0H3AUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

444178:BOV RS01490
gene id: 444178:BOV_RS01490
uniprot id: A0A0H3ALT2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

444178:BOV RS09235
gene id: 444178:BOV_RS09235
uniprot id: A0A0H3ASA7
names: Similarity
messages: Belongs to the arginase family.

444178:BOV RS10515
gene id: 444178:BOV_RS10515
uniprot id: A0A0H3AW46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

444178:BOV RS05565
gene id: 444178:BOV_RS05565
uniprot id: A5VQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

444178:BOV RS04005
gene id: 444178:BOV_RS04005
uniprot id: A0A0H3APT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

444178:BOV RS05930
gene id: 444178:BOV_RS05930
uniprot id: A5VR06
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

444178:BOV RS09095
gene id: 444178:BOV_RS09095
uniprot id: A0A0H3AQB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

444178:BOV RS09850
gene id: 444178:BOV_RS09850
uniprot id: A0A0H3AQQ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

444178:BOV RS03825
gene id: 444178:BOV_RS03825
uniprot id: A5VPV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

444178:BOV RS13475
gene id: 444178:BOV_RS13475
uniprot id: A0A0H3AQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS13705
gene id: 444178:BOV_RS13705
uniprot id: A0A0H3AV67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS09130
gene id: 444178:BOV_RS09130
uniprot id: A0A0H3AQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

444178:BOV RS05540
gene id: 444178:BOV_RS05540
uniprot id: A0A0H3ANN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS00070
gene id: 444178:BOV_RS00070
uniprot id: A0A0H3AQU5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

444178:BOV RS09190
gene id: 444178:BOV_RS09190
uniprot id: A0A0H3AQU9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

444178:BOV RS11245
gene id: 444178:BOV_RS11245
uniprot id: A5VTU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

444178:BOV RS06675
gene id: 444178:BOV_RS06675
uniprot id: A0A0H3AS15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

444178:BOV RS10695
gene id: 444178:BOV_RS10695
uniprot id: A5VTJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

444178:BOV RS09515
gene id: 444178:BOV_RS09515
uniprot id: A0A0H3ART6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

444178:BOV RS12515
gene id: 444178:BOV_RS12515
uniprot id: A0A0H3AT14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS12720
gene id: 444178:BOV_RS12720
uniprot id: A0A0H3AU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

444178:BOV RS07080
gene id: 444178:BOV_RS07080
uniprot id: A0A0H3ANP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

444178:BOV RS11940
gene id: 444178:BOV_RS11940
uniprot id: A0A0H3AV36
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

444178:BOV RS01450
gene id: 444178:BOV_RS01450
uniprot id: A0A0H3AP44
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

444178:BOV RS11970
gene id: 444178:BOV_RS11970
uniprot id: A0A0H3AW03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS08725
gene id: 444178:BOV_RS08725
uniprot id: A5VSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

444178:BOV RS09565
gene id: 444178:BOV_RS09565
uniprot id: A0A0H3APY4
names: Similarity
messages: Belongs to the BolA/IbaG family.

444178:BOV RS05225
gene id: 444178:BOV_RS05225
uniprot id: A0A0H3AQF0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

444178:BOV RS09410
gene id: 444178:BOV_RS09410
uniprot id: A0A0H3ATH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

444178:BOV RS03815
gene id: 444178:BOV_RS03815
uniprot id: A0A0H3AP43
names: Similarity
messages: Belongs to the UPF0174 family.

444178:BOV RS03045
gene id: 444178:BOV_RS03045
uniprot id: A0A0H3AQ98
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

444178:BOV RS12395
gene id: 444178:BOV_RS12395
uniprot id: A0A0H3AS55
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS10740
gene id: 444178:BOV_RS10740
uniprot id: A0A0H3AV24
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

444178:BOV RS10810
gene id: 444178:BOV_RS10810
uniprot id: A0A0H3AUR2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

444178:BOV RS05990
gene id: 444178:BOV_RS05990
uniprot id: A5VR19
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

444178:BOV RS10685
gene id: 444178:BOV_RS10685
uniprot id: A0A0H3ATA6
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00985
gene id: 444178:BOV_RS00985
uniprot id: A0A0H3ASV7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS01980
gene id: 444178:BOV_RS01980
uniprot id: A0A0H3ASN0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

444178:BOV RS01460
gene id: 444178:BOV_RS01460
uniprot id: A5VNL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

444178:BOV RS14055
gene id: 444178:BOV_RS14055
uniprot id: A0A0H3ATW8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS10645
gene id: 444178:BOV_RS10645
uniprot id: A0A0H3ARL1
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

444178:BOV RS01600
gene id: 444178:BOV_RS01600
uniprot id: A5VNP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

444178:BOV RS12740
gene id: 444178:BOV_RS12740
uniprot id: A0A0H3AUV8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

444178:BOV RS02740
gene id: 444178:BOV_RS02740
uniprot id: A5VPA1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

444178:BOV RS04425
gene id: 444178:BOV_RS04425
uniprot id: A5VQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

444178:BOV RS11330
gene id: 444178:BOV_RS11330
uniprot id: A0A0H3ASM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

444178:BOV RS02100
gene id: 444178:BOV_RS02100
uniprot id: A0A0H3API6
names: Similarity
messages: Belongs to the RelE toxin family.

444178:BOV RS06470
gene id: 444178:BOV_RS06470
uniprot id: A0A0H3ANG0
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS15055
gene id: 444178:BOV_RS15055
uniprot id: A0A0H3ATV6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

444178:BOV RS06230
gene id: 444178:BOV_RS06230
uniprot id: A5VR62
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

444178:BOV RS15375
gene id: 444178:BOV_RS15375
uniprot id: A5VVV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

444178:BOV RS15415
gene id: 444178:BOV_RS15415
uniprot id: A0A0H3AUU6
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Membrane
messages: Secreted

444178:BOV RS08010
gene id: 444178:BOV_RS08010
uniprot id: A0A0H3APN0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

444178:BOV RS04485
gene id: 444178:BOV_RS04485
uniprot id: A0A0H3AQ65
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

444178:BOV RS08510
gene id: 444178:BOV_RS08510
uniprot id: A5VSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

444178:BOV RS10375
gene id: 444178:BOV_RS10375
uniprot id: A0A0H3AUT1
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00805
gene id: 444178:BOV_RS00805
uniprot id: A0A0H3AP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

444178:BOV RS10720
gene id: 444178:BOV_RS10720
uniprot id: A0A0H3AWJ7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

444178:BOV RS02415
gene id: 444178:BOV_RS02415
uniprot id: A5VP47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

444178:BOV RS08745
gene id: 444178:BOV_RS08745
uniprot id: A5VSI8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

444178:BOV RS13210
gene id: 444178:BOV_RS13210
uniprot id: A5VUT1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

444178:BOV RS00965
gene id: 444178:BOV_RS00965
uniprot id: A0A0H3APG4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

444178:BOV RS03305
gene id: 444178:BOV_RS03305
uniprot id: A0A0H3AT47
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

444178:BOV RS04665
gene id: 444178:BOV_RS04665
uniprot id: A0A0H3AR93
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

444178:BOV RS08680
gene id: 444178:BOV_RS08680
uniprot id: A5VSH6
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

444178:BOV RS12150
gene id: 444178:BOV_RS12150
uniprot id: A5VU94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NanM family.
messages: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
messages: Homodimer.
messages: Periplasm

444178:BOV RS08300
gene id: 444178:BOV_RS08300
uniprot id: A5VSA3
names: Similarity
messages: Belongs to the UPF0335 family.

444178:BOV RS00455
gene id: 444178:BOV_RS00455
uniprot id: A0A0H3AMJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

444178:BOV RS06555
gene id: 444178:BOV_RS06555
uniprot id: A0A0H3AQ89
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS08415
gene id: 444178:BOV_RS08415
uniprot id: A0A0H3ALS7
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS15805
gene id: 444178:BOV_RS15805
uniprot id: A0A0H3ATK1
names: Function
messages: Component of an amino-acid transport system.

444178:BOV RS08985
gene id: 444178:BOV_RS08985
uniprot id: A0A0H3ARU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS10290
gene id: 444178:BOV_RS10290
uniprot id: A0A0H3ANW8
names: Similarity
messages: Belongs to the peptidase C40 family.

444178:BOV RS08285
gene id: 444178:BOV_RS08285
uniprot id: A0A0H3ARS8
names: Similarity
messages: Belongs to the pyruvate kinase family.

444178:BOV RS03510
gene id: 444178:BOV_RS03510
uniprot id: A0A0H3AP38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

444178:BOV RS08045
gene id: 444178:BOV_RS08045
uniprot id: A0A0H3AR70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

444178:BOV RS03680
gene id: 444178:BOV_RS03680
uniprot id: A0A0H3ANX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

444178:BOV RS10585
gene id: 444178:BOV_RS10585
uniprot id: A0A0H3AU05
names: Similarity
messages: Belongs to the glutamate synthase family.

444178:BOV RS13160
gene id: 444178:BOV_RS13160
uniprot id: A5VUS1
names: Function
names: PTM
messages: FMN binds covalently to cysteine after exposure to blue light and this bond is spontaneously broken in the dark.
messages: Photosensitive kinase that is involved in increased bacterial virulence upon exposure to light. Once ejected from an infected animal host, sunlight acts as an environmental signal that increases the virulence of the bacterium, preparing it for infection of the next host. This photoreceptor protein is directly related to the bacterium's survival and replication within host macrophages (By similarity).

444178:BOV RS01445
gene id: 444178:BOV_RS01445
uniprot id: A0A0H3ARH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

444178:BOV RS12710
gene id: 444178:BOV_RS12710
uniprot id: A0A0H3AUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane.

444178:BOV RS05970
gene id: 444178:BOV_RS05970
uniprot id: A5VR15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

444178:BOV RS14105
gene id: 444178:BOV_RS14105
uniprot id: A0A0H3AVJ4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

444178:BOV RS11555
gene id: 444178:BOV_RS11555
uniprot id: A0A0H3ARZ1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.
messages: Periplasm

444178:BOV RS10595
gene id: 444178:BOV_RS10595
uniprot id: A0A0H3AUD2
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS11065
gene id: 444178:BOV_RS11065
uniprot id: A0A0H3ATE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

444178:BOV RS06780
gene id: 444178:BOV_RS06780
uniprot id: A0A0H3AQD3
names: Similarity
messages: Belongs to the SCO1/2 family.

444178:BOV RS10315
gene id: 444178:BOV_RS10315
uniprot id: A0A0H3AQK6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

444178:BOV RS03710
gene id: 444178:BOV_RS03710
uniprot id: A0A0H3AT24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

444178:BOV RS02285
gene id: 444178:BOV_RS02285
uniprot id: A0A0H3ATI3
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS13435
gene id: 444178:BOV_RS13435
uniprot id: A0A0H3AR39
names: Function
names: Similarity
messages: Belongs to the leucine-binding protein family.
messages: Component of an amino-acid transport system.

444178:BOV RS11730
gene id: 444178:BOV_RS11730
uniprot id: A0A0H3AWB8
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS01035
gene id: 444178:BOV_RS01035
uniprot id: A0A0H3APX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

444178:BOV RS12560
gene id: 444178:BOV_RS12560
uniprot id: A0A0H3AUH7
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS02340
gene id: 444178:BOV_RS02340
uniprot id: A0A0H3ATS0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

444178:BOV RS09595
gene id: 444178:BOV_RS09595
uniprot id: A5VSZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

444178:BOV RS09770
gene id: 444178:BOV_RS09770
uniprot id: A5VT25
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

444178:BOV RS06805
gene id: 444178:BOV_RS06805
uniprot id: A0A0H3AP60
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

444178:BOV RS02325
gene id: 444178:BOV_RS02325
uniprot id: A0A0H3AP06
names: Similarity
messages: Belongs to the fabD family.

444178:BOV RS08890
gene id: 444178:BOV_RS08890
uniprot id: A0A0H3APM7
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS05995
gene id: 444178:BOV_RS05995
uniprot id: A0A0H3APV4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

444178:BOV RS07880
gene id: 444178:BOV_RS07880
uniprot id: A0A0H3AS67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS04945
gene id: 444178:BOV_RS04945
uniprot id: A0A0H3AQH2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

444178:BOV RS13125
gene id: 444178:BOV_RS13125
uniprot id: A0A0H3AUB6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS07345
gene id: 444178:BOV_RS07345
uniprot id: A0A0H3APZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

444178:BOV RS11035
gene id: 444178:BOV_RS11035
uniprot id: A5VTQ7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

444178:BOV RS06520
gene id: 444178:BOV_RS06520
uniprot id: A5VRB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

444178:BOV RS15680
gene id: 444178:BOV_RS15680
uniprot id: A0A0H3ATI7
names: Subcellular Location Annotation
messages: Secreted

444178:BOV RS14485
gene id: 444178:BOV_RS14485
uniprot id: A0A0H3AR58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

444178:BOV RS08500
gene id: 444178:BOV_RS08500
uniprot id: A5VSE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

444178:BOV RS13445
gene id: 444178:BOV_RS13445
uniprot id: A0A0H3AUF7
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS11015
gene id: 444178:BOV_RS11015
uniprot id: A0A0H3ARC8
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

444178:BOV RS02760
gene id: 444178:BOV_RS02760
uniprot id: A5VPA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.

444178:BOV RS00150
gene id: 444178:BOV_RS00150
uniprot id: A0A0H3ARB1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS13270
gene id: 444178:BOV_RS13270
uniprot id: A5VUU3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Essential protein that is involved in the control of cell division, probably through the regulation of ctrA. Its phosphorylation status is regulated by PdhS (By similarity).
messages: Interacts with DivL, PleC, DivJ and PdhS.

444178:BOV RS14180
gene id: 444178:BOV_RS14180
uniprot id: A0A0H3AST9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS08930
gene id: 444178:BOV_RS08930
uniprot id: A0A0H3AQX0
names: Similarity
messages: Belongs to the YciI family.

444178:BOV RS09670
gene id: 444178:BOV_RS09670
uniprot id: A0A0H3AQD0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

444178:BOV RS13555
gene id: 444178:BOV_RS13555
uniprot id: A0A0H3ASW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

444178:BOV RS09015
gene id: 444178:BOV_RS09015
uniprot id: A0A0H3APH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

444178:BOV RS06505
gene id: 444178:BOV_RS06505
uniprot id: A0A0H3APX6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

444178:BOV RS05300
gene id: 444178:BOV_RS05300
uniprot id: A0A0H3ARD0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

444178:BOV RS09290
gene id: 444178:BOV_RS09290
uniprot id: A0A0H3AP91
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

444178:BOV RS01920
gene id: 444178:BOV_RS01920
uniprot id: A0A0H3APU1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Cell membrane
messages: Membrane

444178:BOV RS15180
gene id: 444178:BOV_RS15180
uniprot id: A0A0H3ASB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system.

444178:BOV RS03125
gene id: 444178:BOV_RS03125
uniprot id: A0A0H3AS09
names: Similarity
messages: Belongs to the GST superfamily.

444178:BOV RS15395
gene id: 444178:BOV_RS15395
uniprot id: A0A0H3AU02
names: Similarity
messages: Belongs to the universal stress protein A family.

444178:BOV RS05255
gene id: 444178:BOV_RS05255
uniprot id: A5VQM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

444178:BOV RS07275
gene id: 444178:BOV_RS07275
uniprot id: A5VRQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

444178:BOV RS08470
gene id: 444178:BOV_RS08470
uniprot id: A0A0H3APD6
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS14230
gene id: 444178:BOV_RS14230
uniprot id: A0A0H3AUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

444178:BOV RS15890
gene id: 444178:BOV_RS15890
uniprot id: A5VW32
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Heme transporter.
messages: Induced in absence of iron.

444178:BOV RS14815
gene id: 444178:BOV_RS14815
uniprot id: A0A0H3AVF3
names: Similarity
messages: Belongs to the IlvD/Edd family.

444178:BOV RS05775
gene id: 444178:BOV_RS05775
uniprot id: A5VQX4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

444178:BOV RS04370
gene id: 444178:BOV_RS04370
uniprot id: A0A0H3AQ47
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

444178:BOV RS03895
gene id: 444178:BOV_RS03895
uniprot id: A5VPX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

444178:BOV RS14665
gene id: 444178:BOV_RS14665
uniprot id: A0A0H3AV34
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

444178:BOV RS06830
gene id: 444178:BOV_RS06830
uniprot id: A0A0H3ASK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

444178:BOV RS08055
gene id: 444178:BOV_RS08055
uniprot id: A0A0H3ASH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

444178:BOV RS05395
gene id: 444178:BOV_RS05395
uniprot id: A0A0H3ANB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

444178:BOV RS09590
gene id: 444178:BOV_RS09590
uniprot id: A0A0H3AQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

444178:BOV RS02235
gene id: 444178:BOV_RS02235
uniprot id: A0A0H3APP5
names: Similarity
messages: Belongs to the TlyA family.

444178:BOV RS04825
gene id: 444178:BOV_RS04825
uniprot id: A0A0H3ASF8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS08565
gene id: 444178:BOV_RS08565
uniprot id: A0A0H3ANV3
names: Similarity
messages: Belongs to the SDHAF4 family.

444178:BOV RS14510
gene id: 444178:BOV_RS14510
uniprot id: A0A0H3ASL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

444178:BOV RS02130
gene id: 444178:BOV_RS02130
uniprot id: A0A0H3ASI4
names: Similarity
messages: Belongs to the GARS family.

444178:BOV RS07320
gene id: 444178:BOV_RS07320
uniprot id: A0A0H3AQK5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

444178:BOV RS01705
gene id: 444178:BOV_RS01705
uniprot id: A0A0H3AR15
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

444178:BOV RS11990
gene id: 444178:BOV_RS11990
uniprot id: A0A0H3AS65
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS09305
gene id: 444178:BOV_RS09305
uniprot id: A5VSU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

444178:BOV RS13225
gene id: 444178:BOV_RS13225
uniprot id: A0A0H3AS68
names: Similarity
messages: Belongs to the DprA/Smf family.

444178:BOV RS15185
gene id: 444178:BOV_RS15185
uniprot id: A0A0H3AQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS04065
gene id: 444178:BOV_RS04065
uniprot id: A5VQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS00995
gene id: 444178:BOV_RS00995
uniprot id: A0A0H3AT03
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

444178:BOV RS08545
gene id: 444178:BOV_RS08545
uniprot id: A0A0H3AT71
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

444178:BOV RS11925
gene id: 444178:BOV_RS11925
uniprot id: A5VU57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HdeA family.
messages: Periplasm
messages: Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins.

444178:BOV RS05875
gene id: 444178:BOV_RS05875
uniprot id: A5VQZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

444178:BOV RS10475
gene id: 444178:BOV_RS10475
uniprot id: A0A0H3AUK9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS08200
gene id: 444178:BOV_RS08200
uniprot id: A0A0H3APK7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

444178:BOV RS10895
gene id: 444178:BOV_RS10895
uniprot id: A5VTN1
names: Function
messages: Transcriptional regulator involved in the global control of Brucella gene expression. Mediates the effects of the quorum sensing autoinducer C12-HSL (N-dodecanoyl-homoserine lactone) on a large and diverse number of genes.

444178:BOV RS05685
gene id: 444178:BOV_RS05685
uniprot id: A5VQV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

444178:BOV RS05275
gene id: 444178:BOV_RS05275
uniprot id: A0A0H3AS52
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

444178:BOV RS14530
gene id: 444178:BOV_RS14530
uniprot id: A0A0H3AWC9
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

444178:BOV RS07860
gene id: 444178:BOV_RS07860
uniprot id: A0A0H3AQ77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

444178:BOV RS03700
gene id: 444178:BOV_RS03700
uniprot id: A0A0H3AR20
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

444178:BOV RS12095
gene id: 444178:BOV_RS12095
uniprot id: A0A0H3AU46
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

444178:BOV RS12675
gene id: 444178:BOV_RS12675
uniprot id: A0A0H3AU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

444178:BOV RS03180
gene id: 444178:BOV_RS03180
uniprot id: A5VPH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alphaproteobacteria porin family.
messages: Cell outer membrane
messages: Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.
messages: Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.
messages: Homotrimer.

444178:BOV RS15905
gene id: 444178:BOV_RS15905
uniprot id: A0A0H3ASL1
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS12285
gene id: 444178:BOV_RS12285
uniprot id: A0A0H3AUE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

444178:BOV RS04860
gene id: 444178:BOV_RS04860
uniprot id: A0A0H3AQ87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

444178:BOV RS01735
gene id: 444178:BOV_RS01735
uniprot id: A0A0H3AN96
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00015
gene id: 444178:BOV_RS00015
uniprot id: A0A0H3AT82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

444178:BOV RS05810
gene id: 444178:BOV_RS05810
uniprot id: A5VQY2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

444178:BOV RS03035
gene id: 444178:BOV_RS03035
uniprot id: A5VPF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

444178:BOV RS07120
gene id: 444178:BOV_RS07120
uniprot id: A0A0H3AQ60
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS13750
gene id: 444178:BOV_RS13750
uniprot id: A0A0H3ARQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

444178:BOV RS01125
gene id: 444178:BOV_RS01125
uniprot id: A0A0H3AQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

444178:BOV RS02840
gene id: 444178:BOV_RS02840
uniprot id: A0A0H3AQP3
names: Similarity
messages: Belongs to the peptidase S9A family.

444178:BOV RS15255
gene id: 444178:BOV_RS15255
uniprot id: A5VVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

444178:BOV RS15085
gene id: 444178:BOV_RS15085
uniprot id: A0A0H3ATV9
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS05520
gene id: 444178:BOV_RS05520
uniprot id: A5VQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

444178:BOV RS04750
gene id: 444178:BOV_RS04750
uniprot id: A0A0H3APR2
names: Similarity
messages: Belongs to the ArsC family.

444178:BOV RS00195
gene id: 444178:BOV_RS00195
uniprot id: A5VMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

444178:BOV RS13690
gene id: 444178:BOV_RS13690
uniprot id: A0A0H3ARI0
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS12685
gene id: 444178:BOV_RS12685
uniprot id: A0A0H3AUF2
names: Similarity
messages: Belongs to the peptidase S58 family.

444178:BOV RS09120
gene id: 444178:BOV_RS09120
uniprot id: A5VSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS02870
gene id: 444178:BOV_RS02870
uniprot id: A0A0H3ANS1
names: Similarity
messages: Belongs to the SufE family.

444178:BOV RS00220
gene id: 444178:BOV_RS00220
uniprot id: A0A0H3ARW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

444178:BOV RS04130
gene id: 444178:BOV_RS04130
uniprot id: A5VQ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

444178:BOV RS14615
gene id: 444178:BOV_RS14615
uniprot id: A0A0H3ATM6
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

444178:BOV RS03500
gene id: 444178:BOV_RS03500
uniprot id: A0A0H3APG5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

444178:BOV RS07225
gene id: 444178:BOV_RS07225
uniprot id: A0A0H3ANM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BA14k family.
messages: Cell membrane
messages: Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.
messages: Membrane

444178:BOV RS03490
gene id: 444178:BOV_RS03490
uniprot id: A0A0H3ANX5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

444178:BOV RS06400
gene id: 444178:BOV_RS06400
uniprot id: A0A0H3AN75
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

444178:BOV RS06880
gene id: 444178:BOV_RS06880
uniprot id: A0A0H3APH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

444178:BOV RS15620
gene id: 444178:BOV_RS15620
uniprot id: A5VVZ5
names: Function
names: Similarity
messages: Belongs to the FlbT family.
messages: Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation.

444178:BOV RS11950
gene id: 444178:BOV_RS11950
uniprot id: A0A0H3AUC4
names: Similarity
messages: Belongs to the peptidase S58 family.

444178:BOV RS15555
gene id: 444178:BOV_RS15555
uniprot id: A0A0H3ASV5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

444178:BOV RS08505
gene id: 444178:BOV_RS08505
uniprot id: A5VSE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

444178:BOV RS12625
gene id: 444178:BOV_RS12625
uniprot id: A0A0H3ATD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

444178:BOV RS02375
gene id: 444178:BOV_RS02375
uniprot id: A0A0H3AQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

444178:BOV RS15565
gene id: 444178:BOV_RS15565
uniprot id: A0A0H3AVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

444178:BOV RS10905
gene id: 444178:BOV_RS10905
uniprot id: A0A0H3ARC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

444178:BOV RS00835
gene id: 444178:BOV_RS00835
uniprot id: A0A0H3ARX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

444178:BOV RS11545
gene id: 444178:BOV_RS11545
uniprot id: A0A0H3AVV6
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS09225
gene id: 444178:BOV_RS09225
uniprot id: A0A0H3AQ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

444178:BOV RS00460
gene id: 444178:BOV_RS00460
uniprot id: A0A0H3AR09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

444178:BOV RS11700
gene id: 444178:BOV_RS11700
uniprot id: A0A0H3ASC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

444178:BOV RS06835
gene id: 444178:BOV_RS06835
uniprot id: A0A0H3AT19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

444178:BOV RS08455
gene id: 444178:BOV_RS08455
uniprot id: A0A0H3ASJ3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS15640
gene id: 444178:BOV_RS15640
uniprot id: A0A0H3AWD9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

444178:BOV RS13385
gene id: 444178:BOV_RS13385
uniprot id: A0A0H3AVD7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

444178:BOV RS03975
gene id: 444178:BOV_RS03975
uniprot id: A0A0H3ARL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

444178:BOV RS07465
gene id: 444178:BOV_RS07465
uniprot id: A0A0H3ANM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

444178:BOV RS03205
gene id: 444178:BOV_RS03205
uniprot id: A5VPI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

444178:BOV RS06855
gene id: 444178:BOV_RS06855
uniprot id: A5VRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

444178:BOV RS08845
gene id: 444178:BOV_RS08845
uniprot id: A0A0H3AR44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

444178:BOV RS04480
gene id: 444178:BOV_RS04480
uniprot id: A0A0H3ARS9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

444178:BOV RS13520
gene id: 444178:BOV_RS13520
uniprot id: A0A0H3AS97
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

444178:BOV RS08710
gene id: 444178:BOV_RS08710
uniprot id: A0A0H3AT57
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

444178:BOV RS09175
gene id: 444178:BOV_RS09175
uniprot id: A5VSR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

444178:BOV RS04690
gene id: 444178:BOV_RS04690
uniprot id: A0A0H3APD8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

444178:BOV RS02240
gene id: 444178:BOV_RS02240
uniprot id: A0A0H3AP35
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

444178:BOV RS00665
gene id: 444178:BOV_RS00665
uniprot id: A0A0H3ARQ1
names: Similarity
messages: Belongs to the YkuD family.

444178:BOV RS01430
gene id: 444178:BOV_RS01430
uniprot id: A5VNL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

444178:BOV RS00445
gene id: 444178:BOV_RS00445
uniprot id: A0A0H3ATZ1
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

444178:BOV RS04820
gene id: 444178:BOV_RS04820
uniprot id: A0A0H3AQD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

444178:BOV RS12060
gene id: 444178:BOV_RS12060
uniprot id: A0A0H3ASF2
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS13630
gene id: 444178:BOV_RS13630
uniprot id: A0A0H3AV26
names: Caution
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS14025
gene id: 444178:BOV_RS14025
uniprot id: A0A0H3ATZ9
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

444178:BOV RS14490
gene id: 444178:BOV_RS14490
uniprot id: A5VVE8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

444178:BOV RS11675
gene id: 444178:BOV_RS11675
uniprot id: A0A0H3AU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS00690
gene id: 444178:BOV_RS00690
uniprot id: A5VN81
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

444178:BOV RS05885
gene id: 444178:BOV_RS05885
uniprot id: A5VQZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

444178:BOV RS00165
gene id: 444178:BOV_RS00165
uniprot id: A5VMY2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

444178:BOV RS06215
gene id: 444178:BOV_RS06215
uniprot id: A0A0H3AP95
names: Function
messages: Component of an amino-acid transport system.

444178:BOV RS01020
gene id: 444178:BOV_RS01020
uniprot id: A0A0H3ALZ4
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

444178:BOV RS07285
gene id: 444178:BOV_RS07285
uniprot id: A0A0H3APW8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

444178:BOV RS09805
gene id: 444178:BOV_RS09805
uniprot id: A0A0H3APH1
names: Similarity
messages: Belongs to the Tim44 family.

444178:BOV RS14805
gene id: 444178:BOV_RS14805
uniprot id: A0A0H3ASS7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

444178:BOV RS03445
gene id: 444178:BOV_RS03445
uniprot id: A0A0H3AQQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

444178:BOV RS04020
gene id: 444178:BOV_RS04020
uniprot id: A0A0H3APB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

444178:BOV RS00895
gene id: 444178:BOV_RS00895
uniprot id: A0A0H3ARK8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

444178:BOV RS07445
gene id: 444178:BOV_RS07445
uniprot id: A0A0H3AP87
names: Similarity
messages: Belongs to the OmpW/AlkL family.

444178:BOV RS05075
gene id: 444178:BOV_RS05075
uniprot id: A0A0H3ATZ5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

444178:BOV RS05430
gene id: 444178:BOV_RS05430
uniprot id: A5VQQ7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

444178:BOV RS05305
gene id: 444178:BOV_RS05305
uniprot id: A5VQN3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

444178:BOV RS00475
gene id: 444178:BOV_RS00475
uniprot id: A5VN43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

444178:BOV RS05165
gene id: 444178:BOV_RS05165
uniprot id: A5VQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

444178:BOV RS14175
gene id: 444178:BOV_RS14175
uniprot id: A0A0H3AT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS13260
gene id: 444178:BOV_RS13260
uniprot id: A5VUU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

444178:BOV RS02300
gene id: 444178:BOV_RS02300
uniprot id: A0A0H3AQH7
names: Similarity
messages: Belongs to the CFA/CMAS family.

444178:BOV RS13840
gene id: 444178:BOV_RS13840
uniprot id: A0A0H3ARG5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS02400
gene id: 444178:BOV_RS02400
uniprot id: A0A0H3ANB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

444178:BOV RS15455
gene id: 444178:BOV_RS15455
uniprot id: A5VVX1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

444178:BOV RS03440
gene id: 444178:BOV_RS03440
uniprot id: A0A0H3AR59
names: Similarity
messages: Belongs to the MoaD family.

444178:BOV RS06380
gene id: 444178:BOV_RS06380
uniprot id: A0A0H3ANW0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

444178:BOV RS14475
gene id: 444178:BOV_RS14475
uniprot id: A0A0H3AVB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS15930
gene id: 444178:BOV_RS15930
uniprot id: A0A0H3AUE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

444178:BOV RS14660
gene id: 444178:BOV_RS14660
uniprot id: A0A0H3ATD3
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

444178:BOV RS03235
gene id: 444178:BOV_RS03235
uniprot id: A5VPJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

444178:BOV RS13350
gene id: 444178:BOV_RS13350
uniprot id: A0A0H3AU63
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

444178:BOV RS03905
gene id: 444178:BOV_RS03905
uniprot id: A5VPX4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

444178:BOV RS14775
gene id: 444178:BOV_RS14775
uniprot id: A5VVJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

444178:BOV RS05485
gene id: 444178:BOV_RS05485
uniprot id: A5VQR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

444178:BOV RS01940
gene id: 444178:BOV_RS01940
uniprot id: A0A0H3AR14
names: Cofactor
messages: Binds 1 zinc ion per subunit.

444178:BOV RS07960
gene id: 444178:BOV_RS07960
uniprot id: A0A0H3AMD1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

444178:BOV RS06710
gene id: 444178:BOV_RS06710
uniprot id: A0A0H3AS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS15355
gene id: 444178:BOV_RS15355
uniprot id: A5VVV1
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

444178:BOV RS05955
gene id: 444178:BOV_RS05955
uniprot id: A5VR11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

444178:BOV RS08960
gene id: 444178:BOV_RS08960
uniprot id: A0A0H3APD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

444178:BOV RS14115
gene id: 444178:BOV_RS14115
uniprot id: A0A0H3AQS7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

444178:BOV RS13185
gene id: 444178:BOV_RS13185
uniprot id: A5VUS6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

444178:BOV RS05295
gene id: 444178:BOV_RS05295
uniprot id: A0A0H3ANL9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

444178:BOV RS04075
gene id: 444178:BOV_RS04075
uniprot id: A0A0H3AQA5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS00320
gene id: 444178:BOV_RS00320
uniprot id: A0A0H3ASW0
names: Similarity
messages: Belongs to the virb1 family.

444178:BOV RS05605
gene id: 444178:BOV_RS05605
uniprot id: A0A0H3AQ57
names: Similarity
messages: Belongs to the ClpA/ClpB family.

444178:BOV RS03705
gene id: 444178:BOV_RS03705
uniprot id: A0A0H3ANH1
names: Similarity
messages: Belongs to the GppA/Ppx family.

444178:BOV RS15870
gene id: 444178:BOV_RS15870
uniprot id: A0A0H3AUX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

444178:BOV RS13650
gene id: 444178:BOV_RS13650
uniprot id: A0A0H3AUH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS06875
gene id: 444178:BOV_RS06875
uniprot id: A5VRI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

444178:BOV RS06190
gene id: 444178:BOV_RS06190
uniprot id: A0A0H3ARE2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

444178:BOV RS15270
gene id: 444178:BOV_RS15270
uniprot id: A5VVT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

444178:BOV RS06870
gene id: 444178:BOV_RS06870
uniprot id: A0A0H3AR61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

444178:BOV RS10105
gene id: 444178:BOV_RS10105
uniprot id: A0A0H3ARP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

444178:BOV RS00735
gene id: 444178:BOV_RS00735
uniprot id: A5VN89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

444178:BOV RS07940
gene id: 444178:BOV_RS07940
uniprot id: A0A0H3ANY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

444178:BOV RS02410
gene id: 444178:BOV_RS02410
uniprot id: A5VP46
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

444178:BOV RS08585
gene id: 444178:BOV_RS08585
uniprot id: A5VSF8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

444178:BOV RS02200
gene id: 444178:BOV_RS02200
uniprot id: A0A0H3ANN3
names: Similarity
messages: Belongs to the histone deacetylase family.

444178:BOV RS02195
gene id: 444178:BOV_RS02195
uniprot id: A0A0H3AS01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

444178:BOV RS11605
gene id: 444178:BOV_RS11605
uniprot id: A0A0H3AUZ5
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

444178:BOV RS00865
gene id: 444178:BOV_RS00865
uniprot id: A0A0H3ARD1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

444178:BOV RS07820
gene id: 444178:BOV_RS07820
uniprot id: A0A0H3ARW7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS06285
gene id: 444178:BOV_RS06285
uniprot id: A0A0H3AMF3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

444178:BOV RS04145
gene id: 444178:BOV_RS04145
uniprot id: A0A0H3AT08
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

444178:BOV RS05615
gene id: 444178:BOV_RS05615
uniprot id: A0A0H3ASE6
names: Similarity
messages: Belongs to the peptidase S11 family.

444178:BOV RS01835
gene id: 444178:BOV_RS01835
uniprot id: A0A0H3APS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

444178:BOV RS10855
gene id: 444178:BOV_RS10855
uniprot id: A0A0H3AUI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

444178:BOV RS08365
gene id: 444178:BOV_RS08365
uniprot id: A0A0H3ANN4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

444178:BOV RS14965
gene id: 444178:BOV_RS14965
uniprot id: A0A0H3AS73
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

444178:BOV RS05755
gene id: 444178:BOV_RS05755
uniprot id: A0A0H3AQ86
names: Similarity
messages: Belongs to the peptidase C56 family.

444178:BOV RS13730
gene id: 444178:BOV_RS13730
uniprot id: A0A0H3ATN5
names: Similarity
messages: Belongs to the TPP enzyme family.

444178:BOV RS05950
gene id: 444178:BOV_RS05950
uniprot id: A5VR10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

444178:BOV RS12335
gene id: 444178:BOV_RS12335
uniprot id: A0A0H3ARG1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

444178:BOV RS06660
gene id: 444178:BOV_RS06660
uniprot id: A5VRD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

444178:BOV RS11985
gene id: 444178:BOV_RS11985
uniprot id: A0A0H3AVM2
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS04040
gene id: 444178:BOV_RS04040
uniprot id: A0A0H3AP55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

444178:BOV RS11475
gene id: 444178:BOV_RS11475
uniprot id: A0A0H3AVU1
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS01710
gene id: 444178:BOV_RS01710
uniprot id: A0A0H3AQ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

444178:BOV RS02260
gene id: 444178:BOV_RS02260
uniprot id: A0A0H3AQG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

444178:BOV RS13880
gene id: 444178:BOV_RS13880
uniprot id: A0A0H3AUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS02330
gene id: 444178:BOV_RS02330
uniprot id: A0A0H3ATA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

444178:BOV RS04100
gene id: 444178:BOV_RS04100
uniprot id: A5VQ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

444178:BOV RS08145
gene id: 444178:BOV_RS08145
uniprot id: A5VS71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

444178:BOV RS13485
gene id: 444178:BOV_RS13485
uniprot id: A0A0H3AUN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS14040
gene id: 444178:BOV_RS14040
uniprot id: A0A0H3ATB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

444178:BOV RS14795
gene id: 444178:BOV_RS14795
uniprot id: A0A0H3AUT4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS08155
gene id: 444178:BOV_RS08155
uniprot id: A0A0H3ANL4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS01350
gene id: 444178:BOV_RS01350
uniprot id: A5VNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

444178:BOV RS01740
gene id: 444178:BOV_RS01740
uniprot id: A0A0H3ARB0
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS10940
gene id: 444178:BOV_RS10940
uniprot id: A0A0H3AUV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

444178:BOV RS12700
gene id: 444178:BOV_RS12700
uniprot id: A0A0H3AVH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system.

444178:BOV RS10990
gene id: 444178:BOV_RS10990
uniprot id: A0A0H3ATE6
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS10910
gene id: 444178:BOV_RS10910
uniprot id: A0A0H3AR68
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

444178:BOV RS13255
gene id: 444178:BOV_RS13255
uniprot id: A0A0H3ATV8
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS06650
gene id: 444178:BOV_RS06650
uniprot id: A0A0H3APP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

444178:BOV RS13910
gene id: 444178:BOV_RS13910
uniprot id: A0A0H3AU94
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

444178:BOV RS07540
gene id: 444178:BOV_RS07540
uniprot id: A0A0H3AQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane.

444178:BOV RS04405
gene id: 444178:BOV_RS04405
uniprot id: A0A0H3ANK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

444178:BOV RS02305
gene id: 444178:BOV_RS02305
uniprot id: A5VP24
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

444178:BOV RS08250
gene id: 444178:BOV_RS08250
uniprot id: A0A0H3APX8
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS10045
gene id: 444178:BOV_RS10045
uniprot id: Q05981
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By heat shock.

444178:BOV RS11210
gene id: 444178:BOV_RS11210
uniprot id: A5VTT6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

444178:BOV RS01140
gene id: 444178:BOV_RS01140
uniprot id: A0A0H3AP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS09105
gene id: 444178:BOV_RS09105
uniprot id: A5VSQ4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

444178:BOV RS05840
gene id: 444178:BOV_RS05840
uniprot id: A5VQY8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

444178:BOV RS13885
gene id: 444178:BOV_RS13885
uniprot id: A0A0H3ATQ6
names: Similarity
messages: Belongs to the RutC family.

444178:BOV RS05975
gene id: 444178:BOV_RS05975
uniprot id: A5VR16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

444178:BOV RS15235
gene id: 444178:BOV_RS15235
uniprot id: A5VVS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

444178:BOV RS14890
gene id: 444178:BOV_RS14890
uniprot id: A0A0H3AUE2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS08020
gene id: 444178:BOV_RS08020
uniprot id: A0A0H3AP68
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS09555
gene id: 444178:BOV_RS09555
uniprot id: A0A0H3AS20
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

444178:BOV RS09760
gene id: 444178:BOV_RS09760
uniprot id: A0A0H3ASV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

444178:BOV RS08070
gene id: 444178:BOV_RS08070
uniprot id: A0A0H3ALX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

444178:BOV RS10200
gene id: 444178:BOV_RS10200
uniprot id: A0A0H3AQE0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS01345
gene id: 444178:BOV_RS01345
uniprot id: A0A0H3APU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

444178:BOV RS00630
gene id: 444178:BOV_RS00630
uniprot id: A0A0H3AP15
names: Similarity
messages: Belongs to the FrmR/RcnR family.

444178:BOV RS08140
gene id: 444178:BOV_RS08140
uniprot id: A0A0H3ASD6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS13235
gene id: 444178:BOV_RS13235
uniprot id: A0A0H3ASC9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

444178:BOV RS11625
gene id: 444178:BOV_RS11625
uniprot id: A0A0H3AUQ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

444178:BOV RS03110
gene id: 444178:BOV_RS03110
uniprot id: A0A0H3ANY1
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

444178:BOV RS03400
gene id: 444178:BOV_RS03400
uniprot id: A5VPM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

444178:BOV RS15560
gene id: 444178:BOV_RS15560
uniprot id: A0A0H3AV96
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS07090
gene id: 444178:BOV_RS07090
uniprot id: A0A0H3ARV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

444178:BOV RS06565
gene id: 444178:BOV_RS06565
uniprot id: A0A0H3AQI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

444178:BOV RS13060
gene id: 444178:BOV_RS13060
uniprot id: A0A0H3AVG1
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00285
gene id: 444178:BOV_RS00285
uniprot id: A0A0H3AQ59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS03435
gene id: 444178:BOV_RS03435
uniprot id: A0A0H3ANB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

444178:BOV RS12110
gene id: 444178:BOV_RS12110
uniprot id: A5VU86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system (By similarity).
messages: The complex is composed of two ATP-binding proteins (BOV_A0347 and BOV_A0348), two transmembrane proteins (BOV_A0350 and BOV_A0351) and a solute-binding protein (BOV_A0352).

444178:BOV RS01815
gene id: 444178:BOV_RS01815
uniprot id: A0A0H3APD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

444178:BOV RS04000
gene id: 444178:BOV_RS04000
uniprot id: A0A0H3AP72
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

444178:BOV RS05985
gene id: 444178:BOV_RS05985
uniprot id: A5VR18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

444178:BOV RS04630
gene id: 444178:BOV_RS04630
uniprot id: A0A0H3AMB1
names: Similarity
messages: Belongs to the DEAD box helicase family.

444178:BOV RS05845
gene id: 444178:BOV_RS05845
uniprot id: A5VQY9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

444178:BOV RS06290
gene id: 444178:BOV_RS06290
uniprot id: A0A0H3AS28
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

444178:BOV RS00990
gene id: 444178:BOV_RS00990
uniprot id: A0A0H3AQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS00235
gene id: 444178:BOV_RS00235
uniprot id: A0A0H3AR05
names: Subcellular Location Annotation
messages: Cell outer membrane

444178:BOV RS14565
gene id: 444178:BOV_RS14565
uniprot id: A0A0H3AT02
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS01955
gene id: 444178:BOV_RS01955
uniprot id: A0A0H3ATT1
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS01555
gene id: 444178:BOV_RS01555
uniprot id: A0A0H3APN6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

444178:BOV RS01945
gene id: 444178:BOV_RS01945
uniprot id: A0A0H3AN98
names: Similarity
messages: Belongs to the ArsC family.

444178:BOV RS13405
gene id: 444178:BOV_RS13405
uniprot id: A0A0H3ATZ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

444178:BOV RS12135
gene id: 444178:BOV_RS12135
uniprot id: A5VU91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm
messages: Probably part of an ABC transporter complex that could be involved in peptide import.
messages: The complex is composed of two ATP-binding proteins (BOV_A0347 and BOV_A0348), two transmembrane proteins (BOV_A0350 and BOV_A0351) and a solute-binding protein (BOV_A0352).

444178:BOV RS12030
gene id: 444178:BOV_RS12030
uniprot id: A0A0H3AW15
names: Similarity
messages: Belongs to the XFP family.

444178:BOV RS05340
gene id: 444178:BOV_RS05340
uniprot id: A0A0H3APC7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn regulates CtrA, a transcriptional regulator of the minB operon. The asymmetrical localization of this protein is probably required for cells to enter a new division cycle.
messages: Interacts with DivK.
messages: Membrane

444178:BOV RS11590
gene id: 444178:BOV_RS11590
uniprot id: A0A0H3ASY3
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS12370
gene id: 444178:BOV_RS12370
uniprot id: A0A0H3AUJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS13055
gene id: 444178:BOV_RS13055
uniprot id: A0A0H3AQY3
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS13875
gene id: 444178:BOV_RS13875
uniprot id: A0A0H3AU31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS08465
gene id: 444178:BOV_RS08465
uniprot id: A0A0H3APC2
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS11830
gene id: 444178:BOV_RS11830
uniprot id: A0A0H3ASC2
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

444178:BOV RS11440
gene id: 444178:BOV_RS11440
uniprot id: A0A0H3AQR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

444178:BOV RS09090
gene id: 444178:BOV_RS09090
uniprot id: A5VSQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

444178:BOV RS13675
gene id: 444178:BOV_RS13675
uniprot id: A0A0H3AVP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

444178:BOV RS01505
gene id: 444178:BOV_RS01505
uniprot id: A0A0H3ALS0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

444178:BOV RS10050
gene id: 444178:BOV_RS10050
uniprot id: Q05980
names: Cofactor
names: Domain
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: By heat shock.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

444178:BOV RS10210
gene id: 444178:BOV_RS10210
uniprot id: A0A0H3APE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

444178:BOV RS01595
gene id: 444178:BOV_RS01595
uniprot id: A0A0H3APF1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

444178:BOV RS08320
gene id: 444178:BOV_RS08320
uniprot id: A0A0H3ARM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

444178:BOV RS11835
gene id: 444178:BOV_RS11835
uniprot id: A5VU45
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

444178:BOV RS12905
gene id: 444178:BOV_RS12905
uniprot id: A0A0H3AUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

444178:BOV RS00125
gene id: 444178:BOV_RS00125
uniprot id: A5VMX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

444178:BOV RS09795
gene id: 444178:BOV_RS09795
uniprot id: A5VT30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

444178:BOV RS11045
gene id: 444178:BOV_RS11045
uniprot id: A0A0H3AVC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

444178:BOV RS08925
gene id: 444178:BOV_RS08925
uniprot id: A5VSL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

444178:BOV RS10750
gene id: 444178:BOV_RS10750
uniprot id: A5VTK6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

444178:BOV RS04150
gene id: 444178:BOV_RS04150
uniprot id: A0A0H3AN85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

444178:BOV RS09665
gene id: 444178:BOV_RS09665
uniprot id: A0A0H3ASR9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS08340
gene id: 444178:BOV_RS08340
uniprot id: A0A0H3AN69
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS09610
gene id: 444178:BOV_RS09610
uniprot id: A0A0H3ARJ1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

444178:BOV RS12595
gene id: 444178:BOV_RS12595
uniprot id: A0A0H3AU81
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS10080
gene id: 444178:BOV_RS10080
uniprot id: A0A0H3APB0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

444178:BOV RS08060
gene id: 444178:BOV_RS08060
uniprot id: A5VS52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

444178:BOV RS09265
gene id: 444178:BOV_RS09265
uniprot id: A0A0H3ASU3
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS10760
gene id: 444178:BOV_RS10760
uniprot id: A0A0H3AQW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

444178:BOV RS04320
gene id: 444178:BOV_RS04320
uniprot id: A5VQ54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

444178:BOV RS08040
gene id: 444178:BOV_RS08040
uniprot id: A5VS49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

444178:BOV RS14390
gene id: 444178:BOV_RS14390
uniprot id: A0A0H3AUD7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

444178:BOV RS05055
gene id: 444178:BOV_RS05055
uniprot id: A0A0H3AN07
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

444178:BOV RS13190
gene id: 444178:BOV_RS13190
uniprot id: A5VUS7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

444178:BOV RS02120
gene id: 444178:BOV_RS02120
uniprot id: A0A0H3AN04
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

444178:BOV RS14545
gene id: 444178:BOV_RS14545
uniprot id: A0A0H3AUL9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

444178:BOV RS11310
gene id: 444178:BOV_RS11310
uniprot id: A0A0H3AUV9
names: Similarity
messages: Belongs to the peptidase U62 family.

444178:BOV RS06390
gene id: 444178:BOV_RS06390
uniprot id: A0A0H3ARM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

444178:BOV RS05945
gene id: 444178:BOV_RS05945
uniprot id: A5VR09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

444178:BOV RS06510
gene id: 444178:BOV_RS06510
uniprot id: A0A0H3APC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

444178:BOV RS01580
gene id: 444178:BOV_RS01580
uniprot id: A0A0H3AR74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

444178:BOV RS02360
gene id: 444178:BOV_RS02360
uniprot id: A0A0H3ASM9
names: Similarity
messages: Belongs to the peptidase U62 family.

444178:BOV RS11030
gene id: 444178:BOV_RS11030
uniprot id: A0A0H3AVG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

444178:BOV RS09710
gene id: 444178:BOV_RS09710
uniprot id: A0A0H3APM2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS13585
gene id: 444178:BOV_RS13585
uniprot id: A0A0H3ATH6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS11465
gene id: 444178:BOV_RS11465
uniprot id: A0A0H3ATN0
names: Similarity
messages: Belongs to the DapA family.

444178:BOV RS15445
gene id: 444178:BOV_RS15445
uniprot id: A5VVW9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

444178:BOV RS00715
gene id: 444178:BOV_RS00715
uniprot id: A5VN85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

444178:BOV RS10630
gene id: 444178:BOV_RS10630
uniprot id: P0C538
names: Subcellular Location Annotation
messages: Cell membrane

444178:BOV RS04035
gene id: 444178:BOV_RS04035
uniprot id: A0A0H3APS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

444178:BOV RS06225
gene id: 444178:BOV_RS06225
uniprot id: A0A0H3AS95
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

444178:BOV RS13870
gene id: 444178:BOV_RS13870
uniprot id: A0A0H3ATY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

444178:BOV RS07100
gene id: 444178:BOV_RS07100
uniprot id: A5VRM1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

444178:BOV RS09835
gene id: 444178:BOV_RS09835
uniprot id: A5VT38
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

444178:BOV RS04105
gene id: 444178:BOV_RS04105
uniprot id: A5VQ10
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

444178:BOV RS08000
gene id: 444178:BOV_RS08000
uniprot id: A5VS40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

444178:BOV RS08515
gene id: 444178:BOV_RS08515
uniprot id: A5VSE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

444178:BOV RS01455
gene id: 444178:BOV_RS01455
uniprot id: A0A0H3AN42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

444178:BOV RS06815
gene id: 444178:BOV_RS06815
uniprot id: A5VRG8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

444178:BOV RS10240
gene id: 444178:BOV_RS10240
uniprot id: A5VTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

444178:BOV RS11200
gene id: 444178:BOV_RS11200
uniprot id: A5VTT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS01700
gene id: 444178:BOV_RS01700
uniprot id: A5VNQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

444178:BOV RS03550
gene id: 444178:BOV_RS03550
uniprot id: A0A0H3AQ34
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

444178:BOV RS09260
gene id: 444178:BOV_RS09260
uniprot id: A0A0H3AQR2
names: Similarity
messages: Belongs to the asparaginase 1 family.

444178:BOV RS12275
gene id: 444178:BOV_RS12275
uniprot id: A0A0H3AU76
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

444178:BOV RS14785
gene id: 444178:BOV_RS14785
uniprot id: A0A0H3AUI3
names: Function
messages: Acts on leucine, isoleucine and valine.

444178:BOV RS09250
gene id: 444178:BOV_RS09250
uniprot id: A0A0H3APR7
names: Similarity
messages: Belongs to the asparaginase 1 family.

444178:BOV RS03450
gene id: 444178:BOV_RS03450
uniprot id: A0A0H3ARI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

444178:BOV RS12755
gene id: 444178:BOV_RS12755
uniprot id: A0A0H3AV38
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

444178:BOV RS07670
gene id: 444178:BOV_RS07670
uniprot id: A0A0H3ANK0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

444178:BOV RS10615
gene id: 444178:BOV_RS10615
uniprot id: Q0GK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Cell membrane

444178:BOV RS15125
gene id: 444178:BOV_RS15125
uniprot id: A0A0H3AUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

444178:BOV RS03505
gene id: 444178:BOV_RS03505
uniprot id: A5VPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

444178:BOV RS11240
gene id: 444178:BOV_RS11240
uniprot id: A5VTU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

444178:BOV RS10250
gene id: 444178:BOV_RS10250
uniprot id: A0A0H3ANG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

444178:BOV RS01135
gene id: 444178:BOV_RS01135
uniprot id: A0A0H3AQY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS13615
gene id: 444178:BOV_RS13615
uniprot id: A0A0H3AUT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS03100
gene id: 444178:BOV_RS03100
uniprot id: A0A0H3ASD8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

444178:BOV RS08525
gene id: 444178:BOV_RS08525
uniprot id: A0A0H3ANJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

444178:BOV RS08910
gene id: 444178:BOV_RS08910
uniprot id: A0A0H3ARP5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

444178:BOV RS06525
gene id: 444178:BOV_RS06525
uniprot id: A5VRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

444178:BOV RS12670
gene id: 444178:BOV_RS12670
uniprot id: A0A0H3ATK2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

444178:BOV RS00525
gene id: 444178:BOV_RS00525
uniprot id: A0A0H3ARZ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

444178:BOV RS06630
gene id: 444178:BOV_RS06630
uniprot id: A5VRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

444178:BOV RS15615
gene id: 444178:BOV_RS15615
uniprot id: A0A0H3ASI7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

444178:BOV RS08675
gene id: 444178:BOV_RS08675
uniprot id: A0A0H3ARH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

444178:BOV RS05045
gene id: 444178:BOV_RS05045
uniprot id: A0A0H3ASQ2
names: Similarity
messages: Belongs to the DEAD box helicase family.

444178:BOV RS06010
gene id: 444178:BOV_RS06010
uniprot id: A5VR08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

444178:BOV RS01435
gene id: 444178:BOV_RS01435
uniprot id: A0A0H3APG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

444178:BOV RS14090
gene id: 444178:BOV_RS14090
uniprot id: A0A0H3AQS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

444178:BOV RS03995
gene id: 444178:BOV_RS03995
uniprot id: A0A0H3AS66
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

444178:BOV RS03425
gene id: 444178:BOV_RS03425
uniprot id: A5VPM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

444178:BOV RS10270
gene id: 444178:BOV_RS10270
uniprot id: A0A0H3ANS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

444178:BOV RS12510
gene id: 444178:BOV_RS12510
uniprot id: A0A0H3AV29
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. BioZ family.
messages: Involved in the formation of the biotin precursor pimeloyl-ACP. Catalyzes the condensation of glutaryl-CoA, an intermediate in lysine degradation, with malonyl-ACP to produce 3-oxopimeloyl-ACP.

444178:BOV RS15320
gene id: 444178:BOV_RS15320
uniprot id: A5VVU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

444178:BOV RS11975
gene id: 444178:BOV_RS11975
uniprot id: A0A0H3AUJ4
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

444178:BOV RS00595
gene id: 444178:BOV_RS00595
uniprot id: A0A0H3ASX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

444178:BOV RS09085
gene id: 444178:BOV_RS09085
uniprot id: A0A0H3AR50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

444178:BOV RS02335
gene id: 444178:BOV_RS02335
uniprot id: A5VP30
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

444178:BOV RS14035
gene id: 444178:BOV_RS14035
uniprot id: A5VV73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

444178:BOV RS03250
gene id: 444178:BOV_RS03250
uniprot id: A0A0H3ASV3
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00810
gene id: 444178:BOV_RS00810
uniprot id: A5VNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

444178:BOV RS06665
gene id: 444178:BOV_RS06665
uniprot id: A0A0H3ANT1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

444178:BOV RS05820
gene id: 444178:BOV_RS05820
uniprot id: A5VQY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

444178:BOV RS03385
gene id: 444178:BOV_RS03385
uniprot id: A0A0H3AQP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS00820
gene id: 444178:BOV_RS00820
uniprot id: A5VNA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

444178:BOV RS09830
gene id: 444178:BOV_RS09830
uniprot id: A5VT37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

444178:BOV RS12180
gene id: 444178:BOV_RS12180
uniprot id: A0A0H3AU93
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

444178:BOV RS12895
gene id: 444178:BOV_RS12895
uniprot id: A0A0H3AUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS05025
gene id: 444178:BOV_RS05025
uniprot id: A5VQI8
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

444178:BOV RS15550
gene id: 444178:BOV_RS15550
uniprot id: A0A0H3ARM1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

444178:BOV RS05855
gene id: 444178:BOV_RS05855
uniprot id: A5VQZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

444178:BOV RS01525
gene id: 444178:BOV_RS01525
uniprot id: A5VNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

444178:BOV RS09730
gene id: 444178:BOV_RS09730
uniprot id: A5VT18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

444178:BOV RS01465
gene id: 444178:BOV_RS01465
uniprot id: A5VNL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

444178:BOV RS00515
gene id: 444178:BOV_RS00515
uniprot id: A0A0H3APF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

444178:BOV RS04255
gene id: 444178:BOV_RS04255
uniprot id: A0A0H3ATY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS09720
gene id: 444178:BOV_RS09720
uniprot id: A0A0H3AN90
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

444178:BOV RS05835
gene id: 444178:BOV_RS05835
uniprot id: A5VQY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

444178:BOV RS15950
gene id: 444178:BOV_RS15950
uniprot id: A0A0H3AQM4
names: Similarity
messages: Belongs to the ParB family.

444178:BOV RS09065
gene id: 444178:BOV_RS09065
uniprot id: A0A0H3ASP2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

444178:BOV RS01825
gene id: 444178:BOV_RS01825
uniprot id: A0A0H3ATN3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

444178:BOV RS11680
gene id: 444178:BOV_RS11680
uniprot id: A0A0H3ASX8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS07955
gene id: 444178:BOV_RS07955
uniprot id: A0A0H3ASY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

444178:BOV RS09860
gene id: 444178:BOV_RS09860
uniprot id: A5VT43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

444178:BOV RS01070
gene id: 444178:BOV_RS01070
uniprot id: A0A0H3AQM7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

444178:BOV RS05460
gene id: 444178:BOV_RS05460
uniprot id: A0A0H3ASW7
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

444178:BOV RS08615
gene id: 444178:BOV_RS08615
uniprot id: A5VSG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

444178:BOV RS08180
gene id: 444178:BOV_RS08180
uniprot id: A0A0H3AQL1
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

444178:BOV RS01650
gene id: 444178:BOV_RS01650
uniprot id: A0A0H3ALW2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

444178:BOV RS13700
gene id: 444178:BOV_RS13700
uniprot id: A0A0H3ATR1
names: Subcellular Location Annotation
messages: Cytoplasm

444178:BOV RS05510
gene id: 444178:BOV_RS05510
uniprot id: A0A0H3APV7
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

444178:BOV RS03800
gene id: 444178:BOV_RS03800
uniprot id: A5VPV2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

444178:BOV RS13490
gene id: 444178:BOV_RS13490
uniprot id: A0A0H3AU56
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS14330
gene id: 444178:BOV_RS14330
uniprot id: A0A0H3AUM0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

444178:BOV RS07760
gene id: 444178:BOV_RS07760
uniprot id: A0A0H3AP75
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS06765
gene id: 444178:BOV_RS06765
uniprot id: A0A0H3AP37
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

444178:BOV RS13540
gene id: 444178:BOV_RS13540
uniprot id: A0A0H3ARX5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS13550
gene id: 444178:BOV_RS13550
uniprot id: A0A0H3AUK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

444178:BOV RS12340
gene id: 444178:BOV_RS12340
uniprot id: A0A0H3AU99
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

444178:BOV RS14155
gene id: 444178:BOV_RS14155
uniprot id: A0A0H3ATJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane.

444178:BOV RS00420
gene id: 444178:BOV_RS00420
uniprot id: A0A0H3AQT2
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS02515
gene id: 444178:BOV_RS02515
uniprot id: A0A0H3ASN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

444178:BOV RS05240
gene id: 444178:BOV_RS05240
uniprot id: A5VQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

444178:BOV RS15900
gene id: 444178:BOV_RS15900
uniprot id: A0A0H3ATG0
names: Function
messages: Component of an amino-acid transport system.

444178:BOV RS03775
gene id: 444178:BOV_RS03775
uniprot id: A5VPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS15205
gene id: 444178:BOV_RS15205
uniprot id: A0A0H3AS93
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

444178:BOV RS15845
gene id: 444178:BOV_RS15845
uniprot id: A0A0H3AUM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS12520
gene id: 444178:BOV_RS12520
uniprot id: A5VUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

444178:BOV RS04205
gene id: 444178:BOV_RS04205
uniprot id: A0A0H3ATR4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

444178:BOV RS09705
gene id: 444178:BOV_RS09705
uniprot id: A0A0H3AT55
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS00350
gene id: 444178:BOV_RS00350
uniprot id: A0A0H3ALM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

444178:BOV RS00040
gene id: 444178:BOV_RS00040
uniprot id: A0A0H3APA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS14715
gene id: 444178:BOV_RS14715
uniprot id: A0A0H3AU36
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

444178:BOV RS05465
gene id: 444178:BOV_RS05465
uniprot id: A5VQR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

444178:BOV RS15570
gene id: 444178:BOV_RS15570
uniprot id: A0A0H3ATP2
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

444178:BOV RS04190
gene id: 444178:BOV_RS04190
uniprot id: A0A0H3ARR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

444178:BOV RS00065
gene id: 444178:BOV_RS00065
uniprot id: A0A0H3AR88
names: Function
names: Similarity
messages: Belongs to the leucine-binding protein family.
messages: Component of an amino-acid transport system.

444178:BOV RS01770
gene id: 444178:BOV_RS01770
uniprot id: A0A0H3ASL8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

444178:BOV RS09785
gene id: 444178:BOV_RS09785
uniprot id: A0A0H3ASU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

444178:BOV RS10620
gene id: 444178:BOV_RS10620
uniprot id: A0A0H3AVD0
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

444178:BOV RS06550
gene id: 444178:BOV_RS06550
uniprot id: A0A0H3ARU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

444178:BOV RS07210
gene id: 444178:BOV_RS07210
uniprot id: A0A0H3AT12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

444178:BOV RS05850
gene id: 444178:BOV_RS05850
uniprot id: A5VQZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

444178:BOV RS14850
gene id: 444178:BOV_RS14850
uniprot id: A5VVL2
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S12 family.
messages: Homodimer.
messages: Hydrolyzes N-terminal residues in D-amino acid-containing peptides.
messages: Inhibited by beta-lactam compounds such as 6-aminopenicillic acid, 7-aminocephalosporanic acid, benzylpenicillin and ampicillin. Inhibited by p-chloromercuribenzoate.

444178:BOV RS08265
gene id: 444178:BOV_RS08265
uniprot id: A0A0H3AN64
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

444178:BOV RS12010
gene id: 444178:BOV_RS12010
uniprot id: A0A0H3AU35
names: Similarity
messages: Belongs to the UPF0423 family.

444178:BOV RS06165
gene id: 444178:BOV_RS06165
uniprot id: A0A0H3ARN5
names: Similarity
messages: Belongs to the UPF0758 family.

444178:BOV RS02445
gene id: 444178:BOV_RS02445
uniprot id: A0A0H3AQM8
names: Similarity
messages: Belongs to the peptidase M16 family.

444178:BOV RS04055
gene id: 444178:BOV_RS04055
uniprot id: A0A0H3APC6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

444178:BOV RS03050
gene id: 444178:BOV_RS03050
uniprot id: A0A0H3AQ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

444178:BOV RS03745
gene id: 444178:BOV_RS03745
uniprot id: A0A0H3AQT8
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS03040
gene id: 444178:BOV_RS03040
uniprot id: A0A0H3ARX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS01510
gene id: 444178:BOV_RS01510
uniprot id: A0A0H3APW0
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

444178:BOV RS08560
gene id: 444178:BOV_RS08560
uniprot id: A5VSF3
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

444178:BOV RS14760
gene id: 444178:BOV_RS14760
uniprot id: A5VVJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

444178:BOV RS14060
gene id: 444178:BOV_RS14060
uniprot id: A0A0H3AV47
names: Subcellular Location Annotation
messages: Cell inner membrane

444178:BOV RS13580
gene id: 444178:BOV_RS13580
uniprot id: A0A0H3AV70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

444178:BOV RS14020
gene id: 444178:BOV_RS14020
uniprot id: A0A0H3AVF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS07675
gene id: 444178:BOV_RS07675
uniprot id: A0A0H3ALM9
names: Cofactor
messages: Can also use Mn(2+) ion.

444178:BOV RS04855
gene id: 444178:BOV_RS04855
uniprot id: A0A0H3APN8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

444178:BOV RS02005
gene id: 444178:BOV_RS02005
uniprot id: A5VNW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

444178:BOV RS00915
gene id: 444178:BOV_RS00915
uniprot id: A0A0H3AS38
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

444178:BOV RS10205
gene id: 444178:BOV_RS10205
uniprot id: A5VTA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

444178:BOV RS11780
gene id: 444178:BOV_RS11780
uniprot id: A0A0H3ASG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

444178:BOV RS14905
gene id: 444178:BOV_RS14905
uniprot id: A0A0H3AUA3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

444178:BOV RS05475
gene id: 444178:BOV_RS05475
uniprot id: A5VQR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

444178:BOV RS01760
gene id: 444178:BOV_RS01760
uniprot id: A5VNS0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

444178:BOV RS05285
gene id: 444178:BOV_RS05285
uniprot id: A0A0H3AR03
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

444178:BOV RS04525
gene id: 444178:BOV_RS04525
uniprot id: A0A0H3AQE4
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

444178:BOV RS11810
gene id: 444178:BOV_RS11810
uniprot id: A5VU41
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

444178:BOV RS09170
gene id: 444178:BOV_RS09170
uniprot id: A0A0H3APN1
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

444178:BOV RS10755
gene id: 444178:BOV_RS10755
uniprot id: A0A0H3ASN8
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

444178:BOV RS07155
gene id: 444178:BOV_RS07155
uniprot id: A0A0H3ALM5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

444178:BOV RS05910
gene id: 444178:BOV_RS05910
uniprot id: A5VR02
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

444178:BOV RS08850
gene id: 444178:BOV_RS08850
uniprot id: A0A0H3ANV5
names: Similarity
messages: Belongs to the aspartokinase family.

444178:BOV RS15075
gene id: 444178:BOV_RS15075
uniprot id: A5VVQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

444178:BOV RS09870
gene id: 444178:BOV_RS09870
uniprot id: A5VT45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

444178:BOV RS12575
gene id: 444178:BOV_RS12575
uniprot id: A0A0H3AV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

444178:BOV RS07775
gene id: 444178:BOV_RS07775
uniprot id: A0A0H3AP29
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

444178:BOV RS09100
gene id: 444178:BOV_RS09100
uniprot id: A5VSQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

444178:BOV RS10635
gene id: 444178:BOV_RS10635
uniprot id: A0A0H3AVN3
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

444178:BOV RS06250
gene id: 444178:BOV_RS06250
uniprot id: A0A0H3AQV2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

444178:BOV RS04355
gene id: 444178:BOV_RS04355
uniprot id: A0A0H3ANS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

444178:BOV RS14450
gene id: 444178:BOV_RS14450
uniprot id: A0A0H3AQR0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

444178:BOV RS15430
gene id: 444178:BOV_RS15430
uniprot id: A0A0H3ASE9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

444178:BOV RS01050
gene id: 444178:BOV_RS01050
uniprot id: A0A0H3AQ14
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS14880
gene id: 444178:BOV_RS14880
uniprot id: A0A0H3AUX7
names: Function
messages: Component of an amino-acid transport system.

444178:BOV RS10915
gene id: 444178:BOV_RS10915
uniprot id: A0A0H3ASB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

444178:BOV RS08380
gene id: 444178:BOV_RS08380
uniprot id: A0A0H3AS18
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

444178:BOV RS09275
gene id: 444178:BOV_RS09275
uniprot id: A0A0H3ANI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

444178:BOV RS07380
gene id: 444178:BOV_RS07380
uniprot id: A0A0H3AQE9
names: Subunit
messages: Homodimer.

444178:BOV RS03920
gene id: 444178:BOV_RS03920
uniprot id: A0A0H3ATB6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

444178:BOV RS03990
gene id: 444178:BOV_RS03990
uniprot id: A5VPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

444178:BOV RS06945
gene id: 444178:BOV_RS06945
uniprot id: A0A0H3AN77
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

444178:BOV RS07510
gene id: 444178:BOV_RS07510
uniprot id: A0A0H3AST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

444178:BOV RS14140
gene id: 444178:BOV_RS14140
uniprot id: A0A0H3ASQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA).

444178:BOV RS10020
gene id: 444178:BOV_RS10020
uniprot id: A5VT72
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

444178:BOV RS08610
gene id: 444178:BOV_RS08610
uniprot id: A0A0H3AQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

444178:BOV RS03370
gene id: 444178:BOV_RS03370
uniprot id: A5VPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

444178:BOV RS08305
gene id: 444178:BOV_RS08305
uniprot id: A0A0H3AP78
names: Similarity
messages: Belongs to the ABC transporter superfamily.

444178:BOV RS09335
gene id: 444178:BOV_RS09335
uniprot id: A0A0H3APW4
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS01975
gene id: 444178:BOV_RS01975
uniprot id: A5VNV9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

444178:BOV RS05130
gene id: 444178:BOV_RS05130
uniprot id: A0A0H3APH5
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

444178:BOV RS13960
gene id: 444178:BOV_RS13960
uniprot id: A0A0H3ASJ1
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

444178:BOV RS15855
gene id: 444178:BOV_RS15855
uniprot id: A0A0H3ASI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

444178:BOV RS10555
gene id: 444178:BOV_RS10555
uniprot id: A0A0H3AU61
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

444178:BOV RS06310
gene id: 444178:BOV_RS06310
uniprot id: A0A0H3ASB3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

444178:BOV RS03345
gene id: 444178:BOV_RS03345
uniprot id: A5VPL3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

444178:BOV RS00395
gene id: 444178:BOV_RS00395
uniprot id: A5VN26
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

444178:BOV RS03795
gene id: 444178:BOV_RS03795
uniprot id: A0A0H3AMF8
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

444178:BOV RS00905
gene id: 444178:BOV_RS00905
uniprot id: A0A0H3ATC6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

444178:BOV RS08390
gene id: 444178:BOV_RS08390
uniprot id: A5VSC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

444178:BOV RS14170
gene id: 444178:BOV_RS14170
uniprot id: A0A0H3ATU1
names: Similarity
messages: Belongs to the UxaA family.

444178:BOV RS05935
gene id: 444178:BOV_RS05935
uniprot id: A5VR07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

444178:BOV RS00425
gene id: 444178:BOV_RS00425
uniprot id: A0A0H3AQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

444178:BOV RS02015
gene id: 444178:BOV_RS02015
uniprot id: A5VNW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

444178:BOV RS00390
gene id: 444178:BOV_RS00390
uniprot id: A0A0H3AQS9
names: Subcellular Location Annotation
messages: Membrane

444178:BOV RS08270
gene id: 444178:BOV_RS08270
uniprot id: A0A0H3AQ61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.