43179:Vma21
gene id: 43179:Vma21
uniprot id: I3MGT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

43179:Slc25a43
gene id: 43179:Slc25a43
uniprot id: I3M503
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

43179:ACI67 gp13
gene id: 43179:ACI67_gp13
uniprot id: A0A0U2CJR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Membrane
messages: Mitochondrion inner membrane

43179:LOC101963529
gene id: 43179:LOC101963529
uniprot id: I3LW16
names: Subcellular Location Annotation
messages: Membrane

43179:Ndufa1
gene id: 43179:Ndufa1
uniprot id: I3N4A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

43179:Naa10
gene id: 43179:Naa10
uniprot id: I3MF35
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

43179:Abcd1
gene id: 43179:Abcd1
uniprot id: I3MB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

43179:Ube2a
gene id: 43179:Ube2a
uniprot id: A0A287D4F9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

43179:Ubqln2
gene id: 43179:Ubqln2
uniprot id: I3MM66
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus
messages: autophagosome

43179:Eif1ax
gene id: 43179:Eif1ax
uniprot id: A0A287CZN7
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

43179:LOC101958683
gene id: 43179:LOC101958683
uniprot id: I3NEB3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

43179:Atp1b4
gene id: 43179:Atp1b4
uniprot id: I3M065
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

43179:Usp11
gene id: 43179:Usp11
uniprot id: I3N6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

43179:Fmr1
gene id: 43179:Fmr1
uniprot id: A0A287CX40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

43179:Hcfc1
gene id: 43179:Hcfc1
uniprot id: I3N3V9
names: Subcellular Location Annotation
messages: Nucleus

43179:Gpkow
gene id: 43179:Gpkow
uniprot id: I3MN80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus

43179:Vbp1
gene id: 43179:Vbp1
uniprot id: I3M8C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

43179:ACI67 gp11
gene id: 43179:ACI67_gp11
uniprot id: A0A0U2CKE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

43179:Klhl15
gene id: 43179:Klhl15
uniprot id: I3LZY7
names: Subcellular Location Annotation
messages: Nucleus

43179:Trappc2
gene id: 43179:Trappc2
uniprot id: A0A287D123
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

43179:Dipk2b
gene id: 43179:Dipk2b
uniprot id: I3M073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

43179:Utp14a
gene id: 43179:Utp14a
uniprot id: I3MBB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

43179:Apoo
gene id: 43179:Apoo
uniprot id: I3LZP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

43179:Ssr4
gene id: 43179:Ssr4
uniprot id: I3MBB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

43179:LOC101969868
gene id: 43179:LOC101969868
uniprot id: I3MD22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

43179:Gata1
gene id: 43179:Gata1
uniprot id: I3NB53
names: Subcellular Location Annotation
messages: Nucleus

43179:Kcnd1
gene id: 43179:Kcnd1
uniprot id: I3N2W9
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

43179:Alas2
gene id: 43179:Alas2
uniprot id: I3MAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

43179:Uba1
gene id: 43179:Uba1
uniprot id: I3MGC1
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

43179:Fgd1
gene id: 43179:Fgd1
uniprot id: A0A287CZR1
names: Subcellular Location Annotation
messages: cytoskeleton

43179:Aff2
gene id: 43179:Aff2
uniprot id: A0A287DA17
uniprot id: I3M4X8
names: Similarity
messages: Belongs to the AF4 family.

43179:ACI67 gp08
gene id: 43179:ACI67_gp08
uniprot id: A0A0U2CIH7
uniprot id: Q94UY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MK and ATP5MJ (By similarity). Interacts with DNAJC30; interaction is direct (By similarity).
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

43179:Rbm10
gene id: 43179:Rbm10
uniprot id: A0A287CY21
uniprot id: A0A287D6N3
names: Subcellular Location Annotation
messages: Nucleus

43179:Mid2
gene id: 43179:Mid2
uniprot id: A0A287D3Y2
names: Subcellular Location Annotation
messages: cytoskeleton

43179:Sh3bgrl
gene id: 43179:Sh3bgrl
uniprot id: I3MKK4
names: Similarity
messages: Belongs to the SH3BGR family.

43179:Wnk3
gene id: 43179:Wnk3
uniprot id: I3LWC3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

43179:Pin4
gene id: 43179:Pin4
uniprot id: I3MPK8
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

43179:Atp2b3
gene id: 43179:Atp2b3
uniprot id: A0A287DAQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

43179:Zic3
gene id: 43179:Zic3
uniprot id: I3N6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

43179:Tsr2
gene id: 43179:Tsr2
uniprot id: A0A287D7G0
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

43179:Fam199x
gene id: 43179:Fam199x
uniprot id: I3MCK2
names: Similarity
messages: Belongs to the FAM199 family.

43179:Septin6
gene id: 43179:Septin6
uniprot id: A0A287D365
uniprot id: A0A287DGI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

43179:Usp51
gene id: 43179:Usp51
uniprot id: I3MRB9
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

43179:Pcyt1b
gene id: 43179:Pcyt1b
uniprot id: I3MNS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
messages: Endoplasmic reticulum

43179:LOC101964999
gene id: 43179:LOC101964999
uniprot id: I3LXV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

43179:Chm
gene id: 43179:Chm
uniprot id: I3NCP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

43179:Atrx
gene id: 43179:Atrx
uniprot id: A0A287CYU5
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

43179:LOC101955349
gene id: 43179:LOC101955349
uniprot id: I3N5X7
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

43179:Rp2
gene id: 43179:Rp2
uniprot id: I3MDP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

43179:Yipf6
gene id: 43179:Yipf6
uniprot id: I3NAT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

43179:Armcx3
gene id: 43179:Armcx3
uniprot id: I3MCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane
messages: Mitochondrion outer membrane

43179:Tspan7
gene id: 43179:Tspan7
uniprot id: I3MZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

43179:LOC101974254
gene id: 43179:LOC101974254
uniprot id: I3M2E8
names: Similarity
messages: Belongs to the IAP family.

43179:Prickle3
gene id: 43179:Prickle3
uniprot id: I3MN81
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

43179:Elk1
gene id: 43179:Elk1
uniprot id: I3MEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

43179:LOC101967631
gene id: 43179:LOC101967631
uniprot id: I3NG02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

43179:Ppef1
gene id: 43179:Ppef1
uniprot id: I3N6F4
names: Similarity
messages: Belongs to the PPP phosphatase family.

43179:Rab33a
gene id: 43179:Rab33a
uniprot id: I3MBJ6
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

43179:ACI67 gp02
gene id: 43179:ACI67_gp02
uniprot id: A0A0U2CJS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

43179:Rps6ka3
gene id: 43179:Rps6ka3
uniprot id: I3MFL8
uniprot id: I3MVR1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

43179:Atg4a
gene id: 43179:Atg4a
uniprot id: I3M307
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

43179:Hmgb3
gene id: 43179:Hmgb3
uniprot id: I3N9R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

43179:Uxt
gene id: 43179:Uxt
uniprot id: I3MEI9
names: Similarity
messages: Belongs to the UXT family.

43179:Bhlhb9
gene id: 43179:Bhlhb9
uniprot id: I3N6P5
names: Similarity
messages: Belongs to the GPRASP family.

43179:Tmsb4x
gene id: 43179:Tmsb4x
uniprot id: A0A287CVS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

43179:Apln
gene id: 43179:Apln
uniprot id: A0A287D3D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

43179:Gria3
gene id: 43179:Gria3
uniprot id: A0A287D2U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

43179:Smpx
gene id: 43179:Smpx
uniprot id: I3M0M1
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

43179:Zfx
gene id: 43179:Zfx
uniprot id: I3M974
names: Subcellular Location Annotation
messages: Nucleus

43179:Cited1
gene id: 43179:Cited1
uniprot id: I3MBL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

43179:Bex5
gene id: 43179:Bex5
uniprot id: I3NAB4
names: Similarity
messages: Belongs to the BEX family.

43179:Txlng
gene id: 43179:Txlng
uniprot id: I3M142
names: Similarity
messages: Belongs to the taxilin family.

43179:ACI67 gp05
gene id: 43179:ACI67_gp05
uniprot id: A0A0U2CK51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

43179:LOC101976085
gene id: 43179:LOC101976085
uniprot id: I3MWG8
names: Similarity
messages: Belongs to the profilin family.

43179:Ar
gene id: 43179:Ar
uniprot id: I3MT20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

43179:Heph
gene id: 43179:Heph
uniprot id: I3MPJ1
names: Similarity
messages: Belongs to the multicopper oxidase family.

43179:Stag2
gene id: 43179:Stag2
uniprot id: A0A287D4D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

43179:Cstf2
gene id: 43179:Cstf2
uniprot id: I3NAF8
names: Subcellular Location Annotation
messages: Nucleus

43179:Taf1
gene id: 43179:Taf1
uniprot id: I3MQI9
uniprot id: I3N3C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

43179:Maob
gene id: 43179:Maob
uniprot id: I3M590
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

43179:Timp1
gene id: 43179:Timp1
uniprot id: I3M740
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

43179:Ubl4a
gene id: 43179:Ubl4a
uniprot id: I3NES4
names: Subcellular Location Annotation
messages: cytosol

43179:Asb11
gene id: 43179:Asb11
uniprot id: A0A287DCW3
names: Similarity
messages: Belongs to the ankyrin SOCS box (ASB) family.

43179:Rbm3
gene id: 43179:Rbm3
uniprot id: I3MY48
names: Subcellular Location Annotation
messages: Cytoplasm

43179:Gspt2
gene id: 43179:Gspt2
uniprot id: I3NGZ5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

43179:Fgf13
gene id: 43179:Fgf13
uniprot id: I3MLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

43179:Mbtps2
gene id: 43179:Mbtps2
uniprot id: A0A287DFQ7
names: Similarity
messages: Belongs to the peptidase M50A family.

43179:Kdm5c
gene id: 43179:Kdm5c
uniprot id: I3LY73
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

43179:Actrt1
gene id: 43179:Actrt1
uniprot id: I3N424
names: Similarity
messages: Belongs to the actin family.

43179:Atp6ap2
gene id: 43179:Atp6ap2
uniprot id: I3M634
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

43179:Cxcr3
gene id: 43179:Cxcr3
uniprot id: I3MC56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

43179:Rap2c
gene id: 43179:Rap2c
uniprot id: I3N0C5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

43179:Gpr119
gene id: 43179:Gpr119
uniprot id: I3MPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

43179:LOC101967565
gene id: 43179:LOC101967565
uniprot id: I3N3L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

43179:Rgn
gene id: 43179:Rgn
uniprot id: I3MMS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

43179:Xkrx
gene id: 43179:Xkrx
uniprot id: I3M5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

43179:ACI67 gp03
gene id: 43179:ACI67_gp03
uniprot id: A0A0U2CJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

43179:Mtmr1
gene id: 43179:Mtmr1
uniprot id: I3MQE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

43179:Kif4a
gene id: 43179:Kif4a
uniprot id: I3MDW4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

43179:Slc35a2
gene id: 43179:Slc35a2
uniprot id: I3NC40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

43179:Zdhhc15
gene id: 43179:Zdhhc15
uniprot id: A0A287D1Z8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

43179:Vamp7
gene id: 43179:Vamp7
uniprot id: I3NDB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

43179:Slc25a14
gene id: 43179:Slc25a14
uniprot id: A0A287CVL2
uniprot id: I3MPM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

43179:Gpm6b
gene id: 43179:Gpm6b
uniprot id: A0A287D8N1
uniprot id: A0A287DDW8
uniprot id: A0A287DG39
uniprot id: I3M219
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

43179:Flna
gene id: 43179:Flna
uniprot id: A0A287CWL8
uniprot id: I3M5H3
names: Similarity
messages: Belongs to the filamin family.

43179:Tafazzin
gene id: 43179:Tafazzin
uniprot id: A0A287CTI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

43179:Spin4
gene id: 43179:Spin4
uniprot id: I3MVG9
names: Similarity
messages: Belongs to the SPIN/STSY family.

43179:Dynlt3
gene id: 43179:Dynlt3
uniprot id: I3MXA2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

43179:Apex2
gene id: 43179:Apex2
uniprot id: I3NB59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

43179:Upf3b
gene id: 43179:Upf3b
uniprot id: I3LXZ0
names: Similarity
messages: Belongs to the RENT3 family.

43179:Tceal1
gene id: 43179:Tceal1
uniprot id: I3MU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family. TFA subfamily.
messages: Nucleus

43179:Aifm1
gene id: 43179:Aifm1
uniprot id: I3MBI5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

43179:Xk
gene id: 43179:Xk
uniprot id: I3N3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

43179:ACI67 gp12
gene id: 43179:ACI67_gp12
uniprot id: A0A0U2CL62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

43179:Pir
gene id: 43179:Pir
uniprot id: I3M831
names: Similarity
messages: Belongs to the pirin family.

43179:Ace2
gene id: 43179:Ace2
uniprot id: I3M887
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

43179:S100g
gene id: 43179:S100g
uniprot id: I3LZ85
names: Similarity
messages: Belongs to the S-100 family.

43179:Smc1a
gene id: 43179:Smc1a
uniprot id: I3M666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

43179:Mtm1
gene id: 43179:Mtm1
uniprot id: A0A287CWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

43179:Syn1
gene id: 43179:Syn1
uniprot id: I3MWD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synapsin family.
messages: Golgi apparatus
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: synaptic vesicle

43179:Kcne5
gene id: 43179:Kcne5
uniprot id: I3MJ37
names: Similarity
messages: Belongs to the potassium channel KCNE family.

43179:Brcc3
gene id: 43179:Brcc3
uniprot id: I3N470
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the BRCA1-A complex. Component of the BRISC complex. Both the BRCA1-A complex and the BRISC complex bind polyubiquitin.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

43179:Gdi1
gene id: 43179:Gdi1
uniprot id: I3M479
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

43179:Brs3
gene id: 43179:Brs3
uniprot id: I3MJ93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

43179:Grpr
gene id: 43179:Grpr
uniprot id: I3NBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

43179:Msn
gene id: 43179:Msn
uniprot id: I3MKT8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

43179:Gpr34
gene id: 43179:Gpr34
uniprot id: I3LYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

43179:Gla
gene id: 43179:Gla
uniprot id: I3M4U4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

43179:Awat1
gene id: 43179:Awat1
uniprot id: I3MHD2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

43179:G6pd
gene id: 43179:G6pd
uniprot id: I3N7W5
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

43179:LOC106144991
gene id: 43179:LOC106144991
uniprot id: I3NC25
names: Similarity
messages: Belongs to the SH3BGR family.

43179:LOC101973700
gene id: 43179:LOC101973700
uniprot id: Q5IR82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Monomer. Homodimer. Homotetramer.
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. May increase spectral sensitivity in dim light.

43179:Apool
gene id: 43179:Apool
uniprot id: I3M5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

43179:Rpl10
gene id: 43179:Rpl10
uniprot id: I3MI39
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

43179:ACI67 gp04
gene id: 43179:ACI67_gp04
uniprot id: A0A0U2CJ30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

43179:Plp2
gene id: 43179:Plp2
uniprot id: I3MN84
names: Subcellular Location Annotation
messages: Membrane

43179:Ftsj1
gene id: 43179:Ftsj1
uniprot id: I3N522
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

43179:LOC101959306
gene id: 43179:LOC101959306
uniprot id: I3MUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

43179:Slc7a3
gene id: 43179:Slc7a3
uniprot id: I3MMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

43179:Cnksr2
gene id: 43179:Cnksr2
uniprot id: I3MH95
names: Similarity
messages: Belongs to the CNKSR family.

43179:ACI67 gp10
gene id: 43179:ACI67_gp10
uniprot id: A0A0U2CKU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity). Found in a complex with TMEM177, COA6, COX18, COX20, SCO1 and SCO2. Interacts with TMEM177 in a COX20-dependent manner. Interacts with COX20. Interacts with COX16.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

43179:Bex3
gene id: 43179:Bex3
uniprot id: A0A287CXT3
names: Similarity
messages: Belongs to the BEX family.

43179:Nexmif
gene id: 43179:Nexmif
uniprot id: A0A287CWN9
names: Subcellular Location Annotation
messages: Nucleus

43179:Ctps2
gene id: 43179:Ctps2
uniprot id: I3LZ83
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

43179:Bcap31
gene id: 43179:Bcap31
uniprot id: I3MB38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

43179:Tenm1
gene id: 43179:Tenm1
uniprot id: A0A287D5J4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

43179:Znf449
gene id: 43179:Znf449
uniprot id: I3MU45
names: Subcellular Location Annotation
messages: Nucleus

43179:Ribc1
gene id: 43179:Ribc1
uniprot id: I3M675
names: Similarity
messages: Belongs to the RIB43A family.

43179:Lamp2
gene id: 43179:Lamp2
uniprot id: I3MS28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lysosome membrane

43179:Mid1ip1
gene id: 43179:Mid1ip1
uniprot id: I3N5H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

43179:LOC101975550
gene id: 43179:LOC101975550
uniprot id: I3M427
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane
messages: synaptic vesicle membrane
messages: synaptosome

43179:Rbbp7
gene id: 43179:Rbbp7
uniprot id: I3M161
names: Subcellular Location Annotation
messages: Nucleus

43179:Gpr174
gene id: 43179:Gpr174
uniprot id: I3MF58
names: Subcellular Location Annotation
messages: Membrane

43179:Pou3f4
gene id: 43179:Pou3f4
uniprot id: I3MX42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

43179:Mid1
gene id: 43179:Mid1
uniprot id: I3MKI3
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

43179:Hnrnph2
gene id: 43179:Hnrnph2
uniprot id: I3N5Y0
names: Subcellular Location Annotation
messages: nucleoplasm

43179:Trpc5
gene id: 43179:Trpc5
uniprot id: I3LYD3
names: Subcellular Location Annotation
messages: Membrane

43179:LOC101955644
gene id: 43179:LOC101955644
uniprot id: I3LY16
names: Similarity
messages: Belongs to the NKAP family.

43179:Usp9x
gene id: 43179:Usp9x
uniprot id: I3LXD2
names: Similarity
messages: Belongs to the peptidase C19 family.

43179:Htr2c
gene id: 43179:Htr2c
uniprot id: I3N622
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

43179:Pgk1
gene id: 43179:Pgk1
uniprot id: I3LZI7
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

43179:Nap1l3
gene id: 43179:Nap1l3
uniprot id: A0A287DB88
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

43179:Cldn2
gene id: 43179:Cldn2
uniprot id: I3N275
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

43179:Mecp2
gene id: 43179:Mecp2
uniprot id: A0A287CY93
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

43179:Ids
gene id: 43179:Ids
uniprot id: I3MHX1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

43179:Agtr2
gene id: 43179:Agtr2
uniprot id: I3MJB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

43179:Timm8a
gene id: 43179:Timm8a
uniprot id: I3M4Q9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

43179:F9
gene id: 43179:F9
uniprot id: I3MG53
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

43179:Bgn
gene id: 43179:Bgn
uniprot id: I3MAY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

43179:Morf4l2
gene id: 43179:Morf4l2
uniprot id: I3NA99
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the KAT5/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the MSIN3A histone deacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. Interacts with MRFAP1 and RB1. May also interact with one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of transcriptional repressors.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
messages: Nucleus

43179:Acsl4
gene id: 43179:Acsl4
uniprot id: I3M5T6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

43179:Amer1
gene id: 43179:Amer1
uniprot id: I3MMD2
names: Similarity
messages: Belongs to the Amer family.

43179:Egfl6
gene id: 43179:Egfl6
uniprot id: I3MT28
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

43179:Efnb1
gene id: 43179:Efnb1
uniprot id: I3N370
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

43179:Nr0b1
gene id: 43179:Nr0b1
uniprot id: I3NE22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.

43179:Araf
gene id: 43179:Araf
uniprot id: I3M383
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

43179:LOC101978619
gene id: 43179:LOC101978619
uniprot id: I3MM59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

43179:Prps1
gene id: 43179:Prps1
uniprot id: I3MA44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

43179:LOC101971758
gene id: 43179:LOC101971758
uniprot id: I3MF53
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

43179:LOC101965899
gene id: 43179:LOC101965899
uniprot id: I3MYN5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

43179:Slitrk4
gene id: 43179:Slitrk4
uniprot id: I3NA70
names: Similarity
messages: Belongs to the SLITRK family.

43179:Ogt
gene id: 43179:Ogt
uniprot id: I3MIG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

43179:Rps6ka6
gene id: 43179:Rps6ka6
uniprot id: A0A287CWW4
uniprot id: I3M055
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

43179:Fgf16
gene id: 43179:Fgf16
uniprot id: I3MNJ1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

43179:Ca5b
gene id: 43179:Ca5b
uniprot id: I3MBP7
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

43179:Mospd1
gene id: 43179:Mospd1
uniprot id: I3MB45
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

43179:Dnaaf6
gene id: 43179:Dnaaf6
uniprot id: I3LYR6
names: Similarity
messages: Belongs to the PIH1 family.

43179:Bex4
gene id: 43179:Bex4
uniprot id: I3M3M2
names: Similarity
messages: Belongs to the BEX family.

43179:Sat1
gene id: 43179:Sat1
uniprot id: I3N290
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

43179:Cask
gene id: 43179:Cask
uniprot id: I3N909
names: Similarity
messages: Belongs to the MAGUK family.

43179:Mcts1
gene id: 43179:Mcts1
uniprot id: A0A287CYW1
uniprot id: I3MHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

43179:Gabra3
gene id: 43179:Gabra3
uniprot id: A0A287CSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

43179:LOC101978234
gene id: 43179:LOC101978234
uniprot id: I3N321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

43179:Trex2
gene id: 43179:Trex2
uniprot id: I3N417
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

43179:Smarca1
gene id: 43179:Smarca1
uniprot id: A0A287CVX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

43179:Nap1l2
gene id: 43179:Nap1l2
uniprot id: I3MTA0
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

43179:Hsd17b10
gene id: 43179:Hsd17b10
uniprot id: I3M679
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

43179:Med14
gene id: 43179:Med14
uniprot id: A0A287CYU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

43179:Cdx4
gene id: 43179:Cdx4
uniprot id: I3NCH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

43179:Cdk16
gene id: 43179:Cdk16
uniprot id: A0A287CTJ4
names: Similarity
messages: Belongs to the protein kinase superfamily.

43179:LOC101955809
gene id: 43179:LOC101955809
uniprot id: I3MVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

43179:Suv39h1
gene id: 43179:Suv39h1
uniprot id: I3MPK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

43179:Mpc1l
gene id: 43179:Mpc1l
uniprot id: I3NF13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

43179:Tmem35a
gene id: 43179:Tmem35a
uniprot id: I3M5M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

43179:Srpx
gene id: 43179:Srpx
uniprot id: A0A287DEL2
uniprot id: I3MAD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

43179:Amot
gene id: 43179:Amot
uniprot id: I3MY15
names: Similarity
messages: Belongs to the angiomotin family.

43179:Fundc1
gene id: 43179:Fundc1
uniprot id: I3MVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

43179:Arr3
gene id: 43179:Arr3
uniprot id: Q5DRQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the arrestin family.
messages: Homodimer; disulfide-linked in response to retinal illumination (By similarity). Interacts with CXCR4; the interaction is dependent on the C-terminal phosphorylation of CXCR4 and modulates the calcium ion mobilization activity of CXCR4 (By similarity).
messages: May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins (By similarity).
messages: Photoreceptor inner segment
messages: photoreceptor outer segment

43179:Tent5d
gene id: 43179:Tent5d
uniprot id: I3LX05
names: Similarity
messages: Belongs to the TENT family.

43179:Pfkfb1
gene id: 43179:Pfkfb1
uniprot id: A0A287CUC5
uniprot id: I3MQX9
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

43179:Plxna3
gene id: 43179:Plxna3
uniprot id: I3M2C0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

43179:Cmc4
gene id: 43179:Cmc4
uniprot id: I3NAL5
names: Similarity
messages: Belongs to the CMC4 family.

43179:Gk
gene id: 43179:Gk
uniprot id: A0A287CVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

43179:Gpc3
gene id: 43179:Gpc3
uniprot id: I3MES6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

43179:Zdhhc9
gene id: 43179:Zdhhc9
uniprot id: I3N9M6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

43179:Prps2
gene id: 43179:Prps2
uniprot id: I3M773
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

43179:Tfe3
gene id: 43179:Tfe3
uniprot id: A0A287DDQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

43179:Znf75d
gene id: 43179:Znf75d
uniprot id: I3MKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

43179:Steep1
gene id: 43179:Steep1
uniprot id: A0A287CYQ7
names: Similarity
messages: Belongs to the STEEP1 family.

43179:Cd40lg
gene id: 43179:Cd40lg
uniprot id: I3M7D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

43179:Fam3a
gene id: 43179:Fam3a
uniprot id: I3MY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

43179:Mmgt1
gene id: 43179:Mmgt1
uniprot id: I3M4V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

43179:Nox1
gene id: 43179:Nox1
uniprot id: A0A287CWA3
names: Subcellular Location Annotation
messages: Membrane

43179:Mtmr8
gene id: 43179:Mtmr8
uniprot id: I3N578
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

43179:Foxo4
gene id: 43179:Foxo4
uniprot id: I3NDY8
names: Subcellular Location Annotation
messages: Nucleus

43179:Hprt1
gene id: 43179:Hprt1
uniprot id: A0A287CU32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.
messages: Cytoplasm
messages: Homotetramer.

43179:LOC101955168
gene id: 43179:LOC101955168
uniprot id: I3MTL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

43179:Slc25a5
gene id: 43179:Slc25a5
uniprot id: I3NHB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

43179:Dusp9
gene id: 43179:Dusp9
uniprot id: I3MB09
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

43179:Cltrn
gene id: 43179:Cltrn
uniprot id: I3MC89
names: Subcellular Location Annotation
messages: Membrane

43179:Bclaf3
gene id: 43179:Bclaf3
uniprot id: A0A287DA98
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

43179:Clic2
gene id: 43179:Clic2
uniprot id: I3N2E0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

43179:Zc3h12b
gene id: 43179:Zc3h12b
uniprot id: I3N705
names: Similarity
messages: Belongs to the ZC3H12 family.

43179:LOC101974816
gene id: 43179:LOC101974816
uniprot id: I3MXQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

43179:Gdpd2
gene id: 43179:Gdpd2
uniprot id: I3M4B0
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

43179:Porcn
gene id: 43179:Porcn
uniprot id: I3LXV4
names: Subcellular Location Annotation
messages: Membrane

43179:Gpc4
gene id: 43179:Gpc4
uniprot id: I3MKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

43179:Pdha1
gene id: 43179:Pdha1
uniprot id: I3MPQ9
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

43179:ACI67 gp06
gene id: 43179:ACI67_gp06
uniprot id: A0A0U2CJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with TMEM186. Interacts with TMEM242.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

43179:Lancl3
gene id: 43179:Lancl3
uniprot id: I3MJJ2
names: Similarity
messages: Belongs to the LanC-like protein family.

43179:Slitrk2
gene id: 43179:Slitrk2
uniprot id: I3M1M0
names: Similarity
messages: Belongs to the SLITRK family.

43179:Btk
gene id: 43179:Btk
uniprot id: I3M4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cytoplasm

43179:ACI67 gp01
gene id: 43179:ACI67_gp01
uniprot id: U5IB27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.

43179:Itm2a
gene id: 43179:Itm2a
uniprot id: I3MEW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

43179:Pnck
gene id: 43179:Pnck
uniprot id: I3MB26
names: Similarity
messages: Belongs to the protein kinase superfamily.

43179:Idh3g
gene id: 43179:Idh3g
uniprot id: I3MBB2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

43179:Pabir2
gene id: 43179:Pabir2
uniprot id: A0A287CXT2
uniprot id: A0A287D460
uniprot id: I3M7J5
names: Similarity
messages: Belongs to the FAM122 family.

43179:Praf2
gene id: 43179:Praf2
uniprot id: I3ME07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

43179:Mtcp1
gene id: 43179:Mtcp1
uniprot id: I3M4U7
names: Similarity
messages: Belongs to the TCL1 family.

43179:Ndufb11
gene id: 43179:Ndufb11
uniprot id: I3N3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB11 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane

43179:Wdr45
gene id: 43179:Wdr45
uniprot id: A0A287D8B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure

43179:Gjb1
gene id: 43179:Gjb1
uniprot id: I3NEZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

43179:Tnmd
gene id: 43179:Tnmd
uniprot id: I3NFL5
names: Similarity
messages: Belongs to the chondromodulin-1 family.

43179:Tspan6
gene id: 43179:Tspan6
uniprot id: I3MUR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

43179:Bmx
gene id: 43179:Bmx
uniprot id: A0A287D7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cytoplasm

43179:Msl3
gene id: 43179:Msl3
uniprot id: A0A287D2M6
names: Subcellular Location Annotation
messages: Nucleus

43179:Rragb
gene id: 43179:Rragb
uniprot id: I3M4N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

43179:Otc
gene id: 43179:Otc
uniprot id: I3M3I5
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

43179:ACI67 gp07
gene id: 43179:ACI67_gp07
uniprot id: A0A0U2CK93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane

43179:Tsc22d3
gene id: 43179:Tsc22d3
uniprot id: I3N4Q2
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

43179:Mpp1
gene id: 43179:Mpp1
uniprot id: I3LXX7
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: stereocilium

43179:Phex
gene id: 43179:Phex
uniprot id: I3M8M6
names: Subcellular Location Annotation
messages: Membrane

43179:Cetn2
gene id: 43179:Cetn2
uniprot id: I3N8D8
names: Similarity
messages: Belongs to the centrin family.

43179:Slc16a2
gene id: 43179:Slc16a2
uniprot id: I3MXZ7
names: Subcellular Location Annotation
messages: Membrane

43179:Awat2
gene id: 43179:Awat2
uniprot id: I3LYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

43179:LOC101974845
gene id: 43179:LOC101974845
uniprot id: A0A287DA66
names: Similarity
messages: Belongs to the pro/parathymosin family.

43179:Tmem255a
gene id: 43179:Tmem255a
uniprot id: A0A287CZX5
uniprot id: I3M061
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

43179:Thoc2
gene id: 43179:Thoc2
uniprot id: I3NFC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THOC2 family.
messages: Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.
messages: Nucleus

43179:LOC101967701
gene id: 43179:LOC101967701
uniprot id: I3MA89
names: Similarity
messages: Belongs to the TGF-beta family.

43179:Tmsb15b
gene id: 43179:Tmsb15b
uniprot id: A0A287D9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

43179:Atp6ap1
gene id: 43179:Atp6ap1
uniprot id: A0A287D5Z8
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

43179:Htatsf1
gene id: 43179:Htatsf1
uniprot id: A0A287D7C1
names: Similarity
messages: Belongs to the HTATSF1 family.

43179:Srpx2
gene id: 43179:Srpx2
uniprot id: I3M616
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

43179:Chst7
gene id: 43179:Chst7
uniprot id: I3MX57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

43179:LOC101967130
gene id: 43179:LOC101967130
uniprot id: A0A287CYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

43179:LOC101964462
gene id: 43179:LOC101964462
uniprot id: I3NES9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

43179:Nsdhl
gene id: 43179:Nsdhl
uniprot id: I3N7T2
names: Similarity
messages: Belongs to the 3-beta-HSD family.

43179:Alg13
gene id: 43179:Alg13
uniprot id: A0A287CYM3
uniprot id: A0A287D4N9
uniprot id: I3M8J8
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

43179:Rab39b
gene id: 43179:Rab39b
uniprot id: I3MGX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

43179:Dnase1l1
gene id: 43179:Dnase1l1
uniprot id: I3MI44
names: Similarity
messages: Belongs to the DNase I family.

43179:Phka1
gene id: 43179:Phka1
uniprot id: A0A287CWW5
uniprot id: A0A287D3U1
uniprot id: A0A287D8H3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

43179:Plp1
gene id: 43179:Plp1
uniprot id: I3M3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

43179:LOC101970136
gene id: 43179:LOC101970136
uniprot id: I3M1K0
names: Similarity
messages: Belongs to the GPRASP family.

43179:Nono
gene id: 43179:Nono
uniprot id: I3MQH7
names: Subcellular Location Annotation
messages: Nucleus speckle

43179:Pdk3
gene id: 43179:Pdk3
uniprot id: I3MNR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

43179:Maoa
gene id: 43179:Maoa
uniprot id: I3M574
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

43179:Sh2d1a
gene id: 43179:Sh2d1a
uniprot id: I3MM40
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

43179:Hs6st2
gene id: 43179:Hs6st2
uniprot id: A0A287D1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

43179:LOC101973251
gene id: 43179:LOC101973251
uniprot id: I3MV85
names: Similarity
messages: Belongs to the BEX family.

43179:Glra2
gene id: 43179:Glra2
uniprot id: I3M311
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

43179:LOC101977951
gene id: 43179:LOC101977951
uniprot id: I3MS85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

43179:Lpar4
gene id: 43179:Lpar4
uniprot id: I3N939
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

43179:Nlgn3
gene id: 43179:Nlgn3
uniprot id: A0A287D494
uniprot id: I3MQG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

43179:Pwwp3b
gene id: 43179:Pwwp3b
uniprot id: I3MX44
names: Similarity
messages: Belongs to the PWWP3A family.

43179:LOC101974547
gene id: 43179:LOC101974547
uniprot id: I3MGF2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

43179:Rab9a
gene id: 43179:Rab9a
uniprot id: I3MXS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

43179:Arhgef9
gene id: 43179:Arhgef9
uniprot id: A0A287CTU2
uniprot id: A0A287DB25
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

43179:Gpr173
gene id: 43179:Gpr173
uniprot id: I3MSP5
names: Subcellular Location Annotation
messages: Membrane

43179:Slc9a6
gene id: 43179:Slc9a6
uniprot id: I3MVN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

43179:ACI67 gp09
gene id: 43179:ACI67_gp09
uniprot id: A0A0U2CJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase protein 8 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion membrane

43179:Slc10a3
gene id: 43179:Slc10a3
uniprot id: I3NDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane