429009:ADEG RS10305
gene id: 429009:ADEG_RS10305
uniprot id: C9R9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS03360
gene id: 429009:ADEG_RS03360
uniprot id: C9RC27
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

429009:ADEG RS08440
gene id: 429009:ADEG_RS08440
uniprot id: C9R8Y8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

429009:ADEG RS05115
gene id: 429009:ADEG_RS05115
uniprot id: C9RD15
names: Similarity
messages: Belongs to the histone deacetylase family.

429009:ADEG RS05555
gene id: 429009:ADEG_RS05555
uniprot id: C9RD96
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

429009:ADEG RS01495
gene id: 429009:ADEG_RS01495
uniprot id: C9RB32
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

429009:ADEG RS04590
gene id: 429009:ADEG_RS04590
uniprot id: C9RCR3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

429009:ADEG RS10805
gene id: 429009:ADEG_RS10805
uniprot id: C9RAG8
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

429009:ADEG RS02215
gene id: 429009:ADEG_RS02215
uniprot id: C9RBG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

429009:ADEG RS03035
gene id: 429009:ADEG_RS03035
uniprot id: C9RBX0
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

429009:ADEG RS03295
gene id: 429009:ADEG_RS03295
uniprot id: C9RC20
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

429009:ADEG RS07875
gene id: 429009:ADEG_RS07875
uniprot id: C9R8M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS05835
gene id: 429009:ADEG_RS05835
uniprot id: C9RDE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

429009:ADEG RS07760
gene id: 429009:ADEG_RS07760
uniprot id: C9R8K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

429009:ADEG RS00025
gene id: 429009:ADEG_RS00025
uniprot id: C9RA73
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

429009:ADEG RS09275
gene id: 429009:ADEG_RS09275
uniprot id: C9R9E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS03415
gene id: 429009:ADEG_RS03415
uniprot id: C9RC38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

429009:ADEG RS07610
gene id: 429009:ADEG_RS07610
uniprot id: C9R8H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

429009:ADEG RS10240
gene id: 429009:ADEG_RS10240
uniprot id: C9R9X6
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

429009:ADEG RS00320
gene id: 429009:ADEG_RS00320
uniprot id: C9RAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

429009:ADEG RS00125
gene id: 429009:ADEG_RS00125
uniprot id: C9RA97
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

429009:ADEG RS04205
gene id: 429009:ADEG_RS04205
uniprot id: C9RCJ0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

429009:ADEG RS00220
gene id: 429009:ADEG_RS00220
uniprot id: C9RAB5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

429009:ADEG RS02955
gene id: 429009:ADEG_RS02955
uniprot id: C9RBV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

429009:ADEG RS02900
gene id: 429009:ADEG_RS02900
uniprot id: C9RBU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

429009:ADEG RS03400
gene id: 429009:ADEG_RS03400
uniprot id: C9RC35
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

429009:ADEG RS08995
gene id: 429009:ADEG_RS08995
uniprot id: C9R990
names: Similarity
messages: Belongs to the manganese catalase family.

429009:ADEG RS06490
gene id: 429009:ADEG_RS06490
uniprot id: C9R7W4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

429009:ADEG RS05250
gene id: 429009:ADEG_RS05250
uniprot id: C9RD40
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS01815
gene id: 429009:ADEG_RS01815
uniprot id: C9RB93
names: Similarity
messages: Belongs to the UPF0236 family.

429009:ADEG RS02235
gene id: 429009:ADEG_RS02235
uniprot id: C9RBG7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

429009:ADEG RS08025
gene id: 429009:ADEG_RS08025
uniprot id: C9R8Q7
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS03500
gene id: 429009:ADEG_RS03500
uniprot id: C9RC56
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

429009:ADEG RS01015
gene id: 429009:ADEG_RS01015
uniprot id: C9RAU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

429009:ADEG RS08815
gene id: 429009:ADEG_RS08815
uniprot id: C9R953
names: Similarity
messages: Belongs to the AOR/FOR family.

429009:ADEG RS09945
gene id: 429009:ADEG_RS09945
uniprot id: C9R9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS06620
gene id: 429009:ADEG_RS06620
uniprot id: C9R7Y8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

429009:ADEG RS04510
gene id: 429009:ADEG_RS04510
uniprot id: C9RCP8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

429009:ADEG RS09640
gene id: 429009:ADEG_RS09640
uniprot id: C9R9L1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

429009:ADEG RS02380
gene id: 429009:ADEG_RS02380
uniprot id: C9RBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

429009:ADEG RS02190
gene id: 429009:ADEG_RS02190
uniprot id: C9RBF9
names: Similarity
messages: Belongs to the peptidase C40 family.

429009:ADEG RS10005
gene id: 429009:ADEG_RS10005
uniprot id: C9R9T0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

429009:ADEG RS07600
gene id: 429009:ADEG_RS07600
uniprot id: C9R8H2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

429009:ADEG RS01040
gene id: 429009:ADEG_RS01040
uniprot id: C9RAV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

429009:ADEG RS07470
gene id: 429009:ADEG_RS07470
uniprot id: C9R8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

429009:ADEG RS08190
gene id: 429009:ADEG_RS08190
uniprot id: C9R8T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

429009:ADEG RS00055
gene id: 429009:ADEG_RS00055
uniprot id: C9RA79
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS01565
gene id: 429009:ADEG_RS01565
uniprot id: C9RB47
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

429009:ADEG RS01145
gene id: 429009:ADEG_RS01145
uniprot id: C9RAW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

429009:ADEG RS06000
gene id: 429009:ADEG_RS06000
uniprot id: C9R7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

429009:ADEG RS05830
gene id: 429009:ADEG_RS05830
uniprot id: C9RDE5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

429009:ADEG RS11180
gene id: 429009:ADEG_RS11180
uniprot id: C9RC24
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

429009:ADEG RS03355
gene id: 429009:ADEG_RS03355
uniprot id: C9RC26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

429009:ADEG RS00285
gene id: 429009:ADEG_RS00285
uniprot id: C9RAC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

429009:ADEG RS08220
gene id: 429009:ADEG_RS08220
uniprot id: C9R8U4
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

429009:ADEG RS00315
gene id: 429009:ADEG_RS00315
uniprot id: C9RAD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

429009:ADEG RS04875
gene id: 429009:ADEG_RS04875
uniprot id: C9RCX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

429009:ADEG RS03005
gene id: 429009:ADEG_RS03005
uniprot id: C9RBW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS08430
gene id: 429009:ADEG_RS08430
uniprot id: C9R8Y6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

429009:ADEG RS02760
gene id: 429009:ADEG_RS02760
uniprot id: C9RBR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

429009:ADEG RS00165
gene id: 429009:ADEG_RS00165
uniprot id: C9RAA5
names: Similarity
messages: Belongs to the CutA family.

429009:ADEG RS00635
gene id: 429009:ADEG_RS00635
uniprot id: C9RAM5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

429009:ADEG RS00725
gene id: 429009:ADEG_RS00725
uniprot id: C9RAP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

429009:ADEG RS04355
gene id: 429009:ADEG_RS04355
uniprot id: C9RCM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

429009:ADEG RS04850
gene id: 429009:ADEG_RS04850
uniprot id: C9RCW5
names: Similarity
messages: Belongs to the fabD family.

429009:ADEG RS10065
gene id: 429009:ADEG_RS10065
uniprot id: C9R9U2
names: Similarity
messages: Belongs to the UPF0236 family.

429009:ADEG RS03110
gene id: 429009:ADEG_RS03110
uniprot id: C9RBY5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

429009:ADEG RS09085
gene id: 429009:ADEG_RS09085
uniprot id: C9R9A7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

429009:ADEG RS02580
gene id: 429009:ADEG_RS02580
uniprot id: C9RBN1
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS07050
gene id: 429009:ADEG_RS07050
uniprot id: C9R869
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS08365
gene id: 429009:ADEG_RS08365
uniprot id: C9R8X3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

429009:ADEG RS06165
gene id: 429009:ADEG_RS06165
uniprot id: C9R7Q2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

429009:ADEG RS08380
gene id: 429009:ADEG_RS08380
uniprot id: C9R8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

429009:ADEG RS03020
gene id: 429009:ADEG_RS03020
uniprot id: C9RBW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

429009:ADEG RS00390
gene id: 429009:ADEG_RS00390
uniprot id: C9RAE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

429009:ADEG RS10600
gene id: 429009:ADEG_RS10600
uniprot id: C9RA46
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS04860
gene id: 429009:ADEG_RS04860
uniprot id: C9RCW7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

429009:ADEG RS03090
gene id: 429009:ADEG_RS03090
uniprot id: C9RBY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

429009:ADEG RS06130
gene id: 429009:ADEG_RS06130
uniprot id: C9R7P3
names: Similarity
messages: Belongs to the UPF0047 family.

429009:ADEG RS08640
gene id: 429009:ADEG_RS08640
uniprot id: C9R924
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

429009:ADEG RS00460
gene id: 429009:ADEG_RS00460
uniprot id: C9RAJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

429009:ADEG RS07700
gene id: 429009:ADEG_RS07700
uniprot id: C9R8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

429009:ADEG RS06085
gene id: 429009:ADEG_RS06085
uniprot id: C9R7N4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS02345
gene id: 429009:ADEG_RS02345
uniprot id: C9RBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

429009:ADEG RS02700
gene id: 429009:ADEG_RS02700
uniprot id: C9RBQ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS08070
gene id: 429009:ADEG_RS08070
uniprot id: C9R8R6
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

429009:ADEG RS00675
gene id: 429009:ADEG_RS00675
uniprot id: C9RAN3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

429009:ADEG RS09900
gene id: 429009:ADEG_RS09900
uniprot id: C9R9Q9
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS06370
gene id: 429009:ADEG_RS06370
uniprot id: C9R7U1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

429009:ADEG RS00330
gene id: 429009:ADEG_RS00330
uniprot id: C9RAD7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

429009:ADEG RS05605
gene id: 429009:ADEG_RS05605
uniprot id: C9RDA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

429009:ADEG RS03030
gene id: 429009:ADEG_RS03030
uniprot id: C9RBW9
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS08140
gene id: 429009:ADEG_RS08140
uniprot id: C9R8S8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

429009:ADEG RS06690
gene id: 429009:ADEG_RS06690
uniprot id: C9R802
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

429009:ADEG RS07360
gene id: 429009:ADEG_RS07360
uniprot id: C9R8C6
names: Similarity
messages: Belongs to the universal stress protein A family.

429009:ADEG RS09110
gene id: 429009:ADEG_RS09110
uniprot id: C9R9B2
names: Similarity
messages: Belongs to the universal stress protein A family.

429009:ADEG RS06580
gene id: 429009:ADEG_RS06580
uniprot id: C9R7Y1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

429009:ADEG RS02185
gene id: 429009:ADEG_RS02185
uniprot id: C9RBF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS01935
gene id: 429009:ADEG_RS01935
uniprot id: C9RBB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

429009:ADEG RS10795
gene id: 429009:ADEG_RS10795
uniprot id: C9RAG6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

429009:ADEG RS00170
gene id: 429009:ADEG_RS00170
uniprot id: C9RAA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

429009:ADEG RS10250
gene id: 429009:ADEG_RS10250
uniprot id: C9R9X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

429009:ADEG RS08880
gene id: 429009:ADEG_RS08880
uniprot id: C9R967
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

429009:ADEG RS01515
gene id: 429009:ADEG_RS01515
uniprot id: C9RB36
names: Similarity
messages: Belongs to the UPF0173 family.

429009:ADEG RS02720
gene id: 429009:ADEG_RS02720
uniprot id: C9RBQ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

429009:ADEG RS08415
gene id: 429009:ADEG_RS08415
uniprot id: C9R8Y3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

429009:ADEG RS07845
gene id: 429009:ADEG_RS07845
uniprot id: C9R8M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

429009:ADEG RS09485
gene id: 429009:ADEG_RS09485
uniprot id: C9R9I1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS04840
gene id: 429009:ADEG_RS04840
uniprot id: C9RCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

429009:ADEG RS02925
gene id: 429009:ADEG_RS02925
uniprot id: C9RBU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

429009:ADEG RS07540
gene id: 429009:ADEG_RS07540
uniprot id: C9R8G0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS08305
gene id: 429009:ADEG_RS08305
uniprot id: C9R8W1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

429009:ADEG RS07850
gene id: 429009:ADEG_RS07850
uniprot id: C9R8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

429009:ADEG RS07010
gene id: 429009:ADEG_RS07010
uniprot id: C9R861
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS10145
gene id: 429009:ADEG_RS10145
uniprot id: C9R9V7
names: Similarity
messages: Belongs to the HupF/HypC family.

429009:ADEG RS07480
gene id: 429009:ADEG_RS07480
uniprot id: C9R8F0
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS07145
gene id: 429009:ADEG_RS07145
uniprot id: C9R887
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

429009:ADEG RS05160
gene id: 429009:ADEG_RS05160
uniprot id: C9RD24
names: Similarity
messages: Belongs to the YggT family.

429009:ADEG RS07300
gene id: 429009:ADEG_RS07300
uniprot id: C9R8B5
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS09965
gene id: 429009:ADEG_RS09965
uniprot id: C9R9S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

429009:ADEG RS00385
gene id: 429009:ADEG_RS00385
uniprot id: C9RAE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

429009:ADEG RS03410
gene id: 429009:ADEG_RS03410
uniprot id: C9RC37
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS08250
gene id: 429009:ADEG_RS08250
uniprot id: C9R8V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

429009:ADEG RS10170
gene id: 429009:ADEG_RS10170
uniprot id: C9R9W2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

429009:ADEG RS05180
gene id: 429009:ADEG_RS05180
uniprot id: C9RD28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

429009:ADEG RS10290
gene id: 429009:ADEG_RS10290
uniprot id: C9R9Y6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

429009:ADEG RS08870
gene id: 429009:ADEG_RS08870
uniprot id: C9R965
names: Similarity
messages: Belongs to the peptidase C40 family.

429009:ADEG RS01130
gene id: 429009:ADEG_RS01130
uniprot id: C9RAW6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

429009:ADEG RS11120
gene id: 429009:ADEG_RS11120
uniprot id: C9RBA5
names: Similarity
messages: Belongs to the RecJ family.

429009:ADEG RS08775
gene id: 429009:ADEG_RS08775
uniprot id: C9R948
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

429009:ADEG RS02275
gene id: 429009:ADEG_RS02275
uniprot id: C9RBH5
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

429009:ADEG RS04380
gene id: 429009:ADEG_RS04380
uniprot id: C9RCM5
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

429009:ADEG RS02630
gene id: 429009:ADEG_RS02630
uniprot id: C9RBP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

429009:ADEG RS05150
gene id: 429009:ADEG_RS05150
uniprot id: C9RD22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

429009:ADEG RS00715
gene id: 429009:ADEG_RS00715
uniprot id: C9RAP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

429009:ADEG RS04680
gene id: 429009:ADEG_RS04680
uniprot id: C9RCT1
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

429009:ADEG RS07685
gene id: 429009:ADEG_RS07685
uniprot id: C9R8I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

429009:ADEG RS10295
gene id: 429009:ADEG_RS10295
uniprot id: C9R9Y7
names: Similarity
messages: Belongs to the FlgD family.

429009:ADEG RS08565
gene id: 429009:ADEG_RS08565
uniprot id: C9R909
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

429009:ADEG RS09235
gene id: 429009:ADEG_RS09235
uniprot id: C9R9D5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS07675
gene id: 429009:ADEG_RS07675
uniprot id: C9R8I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

429009:ADEG RS02010
gene id: 429009:ADEG_RS02010
uniprot id: C9RBC6
names: Similarity
messages: Belongs to the ycf81 family.

429009:ADEG RS02715
gene id: 429009:ADEG_RS02715
uniprot id: C9RBQ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

429009:ADEG RS07950
gene id: 429009:ADEG_RS07950
uniprot id: C9R8P2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

429009:ADEG RS01550
gene id: 429009:ADEG_RS01550
uniprot id: C9RB44
names: Similarity
messages: Belongs to the SAICAR synthetase family.

429009:ADEG RS09460
gene id: 429009:ADEG_RS09460
uniprot id: C9R9H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

429009:ADEG RS09070
gene id: 429009:ADEG_RS09070
uniprot id: C9R9A4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

429009:ADEG RS02365
gene id: 429009:ADEG_RS02365
uniprot id: C9RBJ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

429009:ADEG RS06155
gene id: 429009:ADEG_RS06155
uniprot id: C9R7P8
names: Similarity
messages: Belongs to the Fur family.

429009:ADEG RS02075
gene id: 429009:ADEG_RS02075
uniprot id: C9RBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

429009:ADEG RS04270
gene id: 429009:ADEG_RS04270
uniprot id: C9RCK2
names: Similarity
messages: Belongs to the RemA family.

429009:ADEG RS00240
gene id: 429009:ADEG_RS00240
uniprot id: C9RAB9
names: Similarity
messages: Belongs to the peptidase S49 family.

429009:ADEG RS07070
gene id: 429009:ADEG_RS07070
uniprot id: C9R873
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

429009:ADEG RS04780
gene id: 429009:ADEG_RS04780
uniprot id: C9RCV1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

429009:ADEG RS04825
gene id: 429009:ADEG_RS04825
uniprot id: C9RCW1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

429009:ADEG RS10135
gene id: 429009:ADEG_RS10135
uniprot id: C9R9V5
names: Similarity
messages: Belongs to the HypE family.

429009:ADEG RS07905
gene id: 429009:ADEG_RS07905
uniprot id: C9R8N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

429009:ADEG RS02430
gene id: 429009:ADEG_RS02430
uniprot id: C9RBK5
names: Similarity
messages: Belongs to the UPF0236 family.

429009:ADEG RS08405
gene id: 429009:ADEG_RS08405
uniprot id: C9R8Y1
names: Similarity
messages: Belongs to the thioredoxin family.

429009:ADEG RS02970
gene id: 429009:ADEG_RS02970
uniprot id: C9RBV7
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

429009:ADEG RS05665
gene id: 429009:ADEG_RS05665
uniprot id: C9RDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS09410
gene id: 429009:ADEG_RS09410
uniprot id: C9R9G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

429009:ADEG RS03055
gene id: 429009:ADEG_RS03055
uniprot id: C9RBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

429009:ADEG RS10155
gene id: 429009:ADEG_RS10155
uniprot id: C9R9V9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

429009:ADEG RS02355
gene id: 429009:ADEG_RS02355
uniprot id: C9RBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

429009:ADEG RS00805
gene id: 429009:ADEG_RS00805
uniprot id: C9RAQ7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

429009:ADEG RS03895
gene id: 429009:ADEG_RS03895
uniprot id: C9RCD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

429009:ADEG RS01290
gene id: 429009:ADEG_RS01290
uniprot id: C9RAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

429009:ADEG RS10000
gene id: 429009:ADEG_RS10000
uniprot id: C9R9S9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

429009:ADEG RS06185
gene id: 429009:ADEG_RS06185
uniprot id: C9R7Q6
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

429009:ADEG RS08375
gene id: 429009:ADEG_RS08375
uniprot id: C9R8X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

429009:ADEG RS02245
gene id: 429009:ADEG_RS02245
uniprot id: C9RBG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

429009:ADEG RS09260
gene id: 429009:ADEG_RS09260
uniprot id: C9R9E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

429009:ADEG RS06575
gene id: 429009:ADEG_RS06575
uniprot id: C9R7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS06215
gene id: 429009:ADEG_RS06215
uniprot id: C9R7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

429009:ADEG RS07855
gene id: 429009:ADEG_RS07855
uniprot id: C9R8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

429009:ADEG RS09730
gene id: 429009:ADEG_RS09730
uniprot id: C9R9M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

429009:ADEG RS09030
gene id: 429009:ADEG_RS09030
uniprot id: C9R996
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

429009:ADEG RS05165
gene id: 429009:ADEG_RS05165
uniprot id: C9RD25
names: Similarity
messages: Belongs to the UPF0235 family.

429009:ADEG RS03365
gene id: 429009:ADEG_RS03365
uniprot id: C9RC28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

429009:ADEG RS01150
gene id: 429009:ADEG_RS01150
uniprot id: C9RAX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

429009:ADEG RS00230
gene id: 429009:ADEG_RS00230
uniprot id: C9RAB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

429009:ADEG RS06635
gene id: 429009:ADEG_RS06635
uniprot id: C9R7Z1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

429009:ADEG RS10845
gene id: 429009:ADEG_RS10845
uniprot id: C9RAH6
names: Similarity
messages: Belongs to the ParB family.

429009:ADEG RS02395
gene id: 429009:ADEG_RS02395
uniprot id: C9RBJ8
names: Similarity
messages: Belongs to the peptidase S41A family.

429009:ADEG RS07895
gene id: 429009:ADEG_RS07895
uniprot id: C9R8N1
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS02735
gene id: 429009:ADEG_RS02735
uniprot id: C9RBR1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

429009:ADEG RS09470
gene id: 429009:ADEG_RS09470
uniprot id: C9R9H8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

429009:ADEG RS00425
gene id: 429009:ADEG_RS00425
uniprot id: C9RAI8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

429009:ADEG RS01870
gene id: 429009:ADEG_RS01870
uniprot id: C9RBA0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS02260
gene id: 429009:ADEG_RS02260
uniprot id: C9RBH2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

429009:ADEG RS01345
gene id: 429009:ADEG_RS01345
uniprot id: C9RB08
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

429009:ADEG RS09465
gene id: 429009:ADEG_RS09465
uniprot id: C9R9H7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

429009:ADEG RS09115
gene id: 429009:ADEG_RS09115
uniprot id: C9R9B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

429009:ADEG RS10810
gene id: 429009:ADEG_RS10810
uniprot id: C9RAG9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

429009:ADEG RS04315
gene id: 429009:ADEG_RS04315
uniprot id: C9RCL1
names: Subcellular Location Annotation
messages: Cytoplasm

429009:ADEG RS00910
gene id: 429009:ADEG_RS00910
uniprot id: C9RAS8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

429009:ADEG RS07590
gene id: 429009:ADEG_RS07590
uniprot id: C9R8H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

429009:ADEG RS01860
gene id: 429009:ADEG_RS01860
uniprot id: C9RB98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

429009:ADEG RS00035
gene id: 429009:ADEG_RS00035
uniprot id: C9RA75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

429009:ADEG RS07565
gene id: 429009:ADEG_RS07565
uniprot id: C9R8G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

429009:ADEG RS01875
gene id: 429009:ADEG_RS01875
uniprot id: C9RBA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

429009:ADEG RS10035
gene id: 429009:ADEG_RS10035
uniprot id: C9R9T6
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS09450
gene id: 429009:ADEG_RS09450
uniprot id: C9R9H4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

429009:ADEG RS01490
gene id: 429009:ADEG_RS01490
uniprot id: C9RB31
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

429009:ADEG RS09230
gene id: 429009:ADEG_RS09230
uniprot id: C9R9D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

429009:ADEG RS01750
gene id: 429009:ADEG_RS01750
uniprot id: C9RB83
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS02150
gene id: 429009:ADEG_RS02150
uniprot id: C9RBF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

429009:ADEG RS02895
gene id: 429009:ADEG_RS02895
uniprot id: C9RBU2
names: Similarity
messages: Belongs to the DprA/Smf family.

429009:ADEG RS06520
gene id: 429009:ADEG_RS06520
uniprot id: C9R7W9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

429009:ADEG RS10265
gene id: 429009:ADEG_RS10265
uniprot id: C9R9Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

429009:ADEG RS06295
gene id: 429009:ADEG_RS06295
uniprot id: C9R7S7
names: Similarity
messages: Belongs to the GerABKA family.

429009:ADEG RS02295
gene id: 429009:ADEG_RS02295
uniprot id: C9RBH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

429009:ADEG RS00300
gene id: 429009:ADEG_RS00300
uniprot id: C9RAD1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

429009:ADEG RS00235
gene id: 429009:ADEG_RS00235
uniprot id: C9RAB8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS00795
gene id: 429009:ADEG_RS00795
uniprot id: C9RAQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

429009:ADEG RS08625
gene id: 429009:ADEG_RS08625
uniprot id: C9R921
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

429009:ADEG RS10780
gene id: 429009:ADEG_RS10780
uniprot id: C9RAG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

429009:ADEG RS06040
gene id: 429009:ADEG_RS06040
uniprot id: C9R7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

429009:ADEG RS05595
gene id: 429009:ADEG_RS05595
uniprot id: C9RDA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS01030
gene id: 429009:ADEG_RS01030
uniprot id: C9RAU8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

429009:ADEG RS00810
gene id: 429009:ADEG_RS00810
uniprot id: C9RAQ8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

429009:ADEG RS05725
gene id: 429009:ADEG_RS05725
uniprot id: C9RDC4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS01560
gene id: 429009:ADEG_RS01560
uniprot id: C9RB46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

429009:ADEG RS03175
gene id: 429009:ADEG_RS03175
uniprot id: C9RBZ8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS07595
gene id: 429009:ADEG_RS07595
uniprot id: C9R8H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

429009:ADEG RS01555
gene id: 429009:ADEG_RS01555
uniprot id: C9RB45
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

429009:ADEG RS02420
gene id: 429009:ADEG_RS02420
uniprot id: C9RBK3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

429009:ADEG RS02485
gene id: 429009:ADEG_RS02485
uniprot id: C9RBL3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

429009:ADEG RS08920
gene id: 429009:ADEG_RS08920
uniprot id: C9R975
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

429009:ADEG RS10300
gene id: 429009:ADEG_RS10300
uniprot id: C9R9Y8
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

429009:ADEG RS00615
gene id: 429009:ADEG_RS00615
uniprot id: C9RAM2
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

429009:ADEG RS02480
gene id: 429009:ADEG_RS02480
uniprot id: C9RBL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

429009:ADEG RS08710
gene id: 429009:ADEG_RS08710
uniprot id: C9R938
names: Similarity
messages: Belongs to the GSP E family.

429009:ADEG RS03370
gene id: 429009:ADEG_RS03370
uniprot id: C9RC29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS01570
gene id: 429009:ADEG_RS01570
uniprot id: C9RB48
names: Similarity
messages: Belongs to the GARS family.

429009:ADEG RS00495
gene id: 429009:ADEG_RS00495
uniprot id: C9RAK2
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS05795
gene id: 429009:ADEG_RS05795
uniprot id: C9RDD8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

429009:ADEG RS09955
gene id: 429009:ADEG_RS09955
uniprot id: C9R9S0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

429009:ADEG RS10285
gene id: 429009:ADEG_RS10285
uniprot id: C9R9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

429009:ADEG RS10310
gene id: 429009:ADEG_RS10310
uniprot id: C9R9Z0
names: Subcellular Location Annotation
messages: Cytoplasm

429009:ADEG RS00445
gene id: 429009:ADEG_RS00445
uniprot id: C9RAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

429009:ADEG RS00045
gene id: 429009:ADEG_RS00045
uniprot id: C9RA77
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

429009:ADEG RS02605
gene id: 429009:ADEG_RS02605
uniprot id: C9RBN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

429009:ADEG RS09210
gene id: 429009:ADEG_RS09210
uniprot id: C9R9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

429009:ADEG RS07550
gene id: 429009:ADEG_RS07550
uniprot id: C9R8G2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

429009:ADEG RS01430
gene id: 429009:ADEG_RS01430
uniprot id: C9RB21
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

429009:ADEG RS07715
gene id: 429009:ADEG_RS07715
uniprot id: C9R8J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

429009:ADEG RS02270
gene id: 429009:ADEG_RS02270
uniprot id: C9RBH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

429009:ADEG RS01595
gene id: 429009:ADEG_RS01595
uniprot id: C9RB53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

429009:ADEG RS02225
gene id: 429009:ADEG_RS02225
uniprot id: C9RBG5
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

429009:ADEG RS08510
gene id: 429009:ADEG_RS08510
uniprot id: C9R903
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS08850
gene id: 429009:ADEG_RS08850
uniprot id: C9R961
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

429009:ADEG RS06360
gene id: 429009:ADEG_RS06360
uniprot id: C9R7T9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

429009:ADEG RS09515
gene id: 429009:ADEG_RS09515
uniprot id: C9R9I7
names: Similarity
messages: Belongs to the HdrA family.

429009:ADEG RS08885
gene id: 429009:ADEG_RS08885
uniprot id: C9R968
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

429009:ADEG RS01170
gene id: 429009:ADEG_RS01170
uniprot id: C9RAX4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

429009:ADEG RS01775
gene id: 429009:ADEG_RS01775
uniprot id: C9RB88
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

429009:ADEG RS07115
gene id: 429009:ADEG_RS07115
uniprot id: C9R881
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

429009:ADEG RS09545
gene id: 429009:ADEG_RS09545
uniprot id: C9R9J2
names: Similarity
messages: Belongs to the glutamine synthetase family.

429009:ADEG RS08930
gene id: 429009:ADEG_RS08930
uniprot id: C9R977
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

429009:ADEG RS07780
gene id: 429009:ADEG_RS07780
uniprot id: C9R8K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

429009:ADEG RS01330
gene id: 429009:ADEG_RS01330
uniprot id: C9RB04
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

429009:ADEG RS07160
gene id: 429009:ADEG_RS07160
uniprot id: C9R890
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

429009:ADEG RS08765
gene id: 429009:ADEG_RS08765
uniprot id: C9R946
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

429009:ADEG RS10160
gene id: 429009:ADEG_RS10160
uniprot id: C9R9W0
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

429009:ADEG RS07665
gene id: 429009:ADEG_RS07665
uniprot id: C9R8I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

429009:ADEG RS00305
gene id: 429009:ADEG_RS00305
uniprot id: C9RAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

429009:ADEG RS02785
gene id: 429009:ADEG_RS02785
uniprot id: C9RBS1
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS09615
gene id: 429009:ADEG_RS09615
uniprot id: C9R9K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

429009:ADEG RS04795
gene id: 429009:ADEG_RS04795
uniprot id: C9RCV4
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

429009:ADEG RS02965
gene id: 429009:ADEG_RS02965
uniprot id: C9RBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

429009:ADEG RS00680
gene id: 429009:ADEG_RS00680
uniprot id: C9RAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

429009:ADEG RS04565
gene id: 429009:ADEG_RS04565
uniprot id: C9RCQ8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS07920
gene id: 429009:ADEG_RS07920
uniprot id: C9R8N6
names: Similarity
messages: Belongs to the transpeptidase family.

429009:ADEG RS06660
gene id: 429009:ADEG_RS06660
uniprot id: C9R7Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

429009:ADEG RS02845
gene id: 429009:ADEG_RS02845
uniprot id: C9RBT2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

429009:ADEG RS07730
gene id: 429009:ADEG_RS07730
uniprot id: C9R8J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

429009:ADEG RS10335
gene id: 429009:ADEG_RS10335
uniprot id: C9R9Z5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

429009:ADEG RS03905
gene id: 429009:ADEG_RS03905
uniprot id: C9RCD5
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS00905
gene id: 429009:ADEG_RS00905
uniprot id: C9RAS7
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

429009:ADEG RS01475
gene id: 429009:ADEG_RS01475
uniprot id: C9RB28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

429009:ADEG RS06715
gene id: 429009:ADEG_RS06715
uniprot id: C9R807
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

429009:ADEG RS07930
gene id: 429009:ADEG_RS07930
uniprot id: C9R8N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

429009:ADEG RS02385
gene id: 429009:ADEG_RS02385
uniprot id: C9RBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

429009:ADEG RS08310
gene id: 429009:ADEG_RS08310
uniprot id: C9R8W2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

429009:ADEG RS04885
gene id: 429009:ADEG_RS04885
uniprot id: C9RCX2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

429009:ADEG RS07575
gene id: 429009:ADEG_RS07575
uniprot id: C9R8G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

429009:ADEG RS00210
gene id: 429009:ADEG_RS00210
uniprot id: C9RAB3
names: Similarity
messages: Belongs to the UPF0236 family.

429009:ADEG RS05025
gene id: 429009:ADEG_RS05025
uniprot id: C9RCZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

429009:ADEG RS01155
gene id: 429009:ADEG_RS01155
uniprot id: C9RAX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

429009:ADEG RS08330
gene id: 429009:ADEG_RS08330
uniprot id: C9R8W6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

429009:ADEG RS02455
gene id: 429009:ADEG_RS02455
uniprot id: C9RBK7
names: Similarity
messages: Belongs to the EamA transporter family.

429009:ADEG RS10510
gene id: 429009:ADEG_RS10510
uniprot id: C9RA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

429009:ADEG RS10800
gene id: 429009:ADEG_RS10800
uniprot id: C9RAG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

429009:ADEG RS02135
gene id: 429009:ADEG_RS02135
uniprot id: C9RBE7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS09735
gene id: 429009:ADEG_RS09735
uniprot id: C9R9M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

429009:ADEG RS08145
gene id: 429009:ADEG_RS08145
uniprot id: C9R8S9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

429009:ADEG RS07725
gene id: 429009:ADEG_RS07725
uniprot id: C9R8J7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

429009:ADEG RS01985
gene id: 429009:ADEG_RS01985
uniprot id: C9RBC2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

429009:ADEG RS02800
gene id: 429009:ADEG_RS02800
uniprot id: C9RBS4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

429009:ADEG RS06665
gene id: 429009:ADEG_RS06665
uniprot id: C9R7Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

429009:ADEG RS05810
gene id: 429009:ADEG_RS05810
uniprot id: C9RDE1
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

429009:ADEG RS07135
gene id: 429009:ADEG_RS07135
uniprot id: C9R885
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

429009:ADEG RS09255
gene id: 429009:ADEG_RS09255
uniprot id: C9R9D9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

429009:ADEG RS10215
gene id: 429009:ADEG_RS10215
uniprot id: C9R9X1
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

429009:ADEG RS08090
gene id: 429009:ADEG_RS08090
uniprot id: C9R8S0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

429009:ADEG RS07900
gene id: 429009:ADEG_RS07900
uniprot id: C9R8N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

429009:ADEG RS05465
gene id: 429009:ADEG_RS05465
uniprot id: C9RD79
names: Similarity
messages: Belongs to the HdrA family.

429009:ADEG RS07125
gene id: 429009:ADEG_RS07125
uniprot id: C9R883
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

429009:ADEG RS04740
gene id: 429009:ADEG_RS04740
uniprot id: C9RCU3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

429009:ADEG RS05280
gene id: 429009:ADEG_RS05280
uniprot id: C9RD46
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS02080
gene id: 429009:ADEG_RS02080
uniprot id: C9RBD6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS07660
gene id: 429009:ADEG_RS07660
uniprot id: C9R8I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

429009:ADEG RS04670
gene id: 429009:ADEG_RS04670
uniprot id: C9RCS9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

429009:ADEG RS00785
gene id: 429009:ADEG_RS00785
uniprot id: C9RAQ3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

429009:ADEG RS07755
gene id: 429009:ADEG_RS07755
uniprot id: C9R8K3
names: Similarity
messages: Belongs to the transpeptidase family.

429009:ADEG RS07640
gene id: 429009:ADEG_RS07640
uniprot id: C9R8I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

429009:ADEG RS08560
gene id: 429009:ADEG_RS08560
uniprot id: C9R908
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

429009:ADEG RS09500
gene id: 429009:ADEG_RS09500
uniprot id: C9R9I4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: In the N-terminal section; belongs to the DHNA family.

429009:ADEG RS07340
gene id: 429009:ADEG_RS07340
uniprot id: C9R8C3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

429009:ADEG RS04890
gene id: 429009:ADEG_RS04890
uniprot id: C9RCX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

429009:ADEG RS10245
gene id: 429009:ADEG_RS10245
uniprot id: C9R9X7
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

429009:ADEG RS05405
gene id: 429009:ADEG_RS05405
uniprot id: C9RD69
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS06440
gene id: 429009:ADEG_RS06440
uniprot id: C9R7V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

429009:ADEG RS01855
gene id: 429009:ADEG_RS01855
uniprot id: C9RB97
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

429009:ADEG RS02880
gene id: 429009:ADEG_RS02880
uniprot id: C9RBT9
names: Similarity
messages: Belongs to the threonine synthase family.

429009:ADEG RS01575
gene id: 429009:ADEG_RS01575
uniprot id: C9RB49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

429009:ADEG RS02770
gene id: 429009:ADEG_RS02770
uniprot id: C9RBR8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

429009:ADEG RS11275
gene id: 429009:ADEG_RS11275
uniprot id: C9RCT8
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS09745
gene id: 429009:ADEG_RS09745
uniprot id: C9R9N1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

429009:ADEG RS10745
gene id: 429009:ADEG_RS10745
uniprot id: C9RAG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

429009:ADEG RS07750
gene id: 429009:ADEG_RS07750
uniprot id: C9R8K2
names: Similarity
messages: Belongs to the Fur family.

429009:ADEG RS10450
gene id: 429009:ADEG_RS10450
uniprot id: C9RA18
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

429009:ADEG RS08395
gene id: 429009:ADEG_RS08395
uniprot id: C9R8X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

429009:ADEG RS09185
gene id: 429009:ADEG_RS09185
uniprot id: C9R9C5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

429009:ADEG RS06380
gene id: 429009:ADEG_RS06380
uniprot id: C9R7U3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

429009:ADEG RS00015
gene id: 429009:ADEG_RS00015
uniprot id: C9RA71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

429009:ADEG RS10790
gene id: 429009:ADEG_RS10790
uniprot id: C9RAG5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

429009:ADEG RS09805
gene id: 429009:ADEG_RS09805
uniprot id: C9R9P2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

429009:ADEG RS01885
gene id: 429009:ADEG_RS01885
uniprot id: C9RBA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

429009:ADEG RS09940
gene id: 429009:ADEG_RS09940
uniprot id: C9R9R7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

429009:ADEG RS06485
gene id: 429009:ADEG_RS06485
uniprot id: C9R7W3
names: Similarity
messages: Belongs to the asp23 family.

429009:ADEG RS01460
gene id: 429009:ADEG_RS01460
uniprot id: C9RB25
names: Similarity
messages: Belongs to the peptidase A31 family.

429009:ADEG RS08700
gene id: 429009:ADEG_RS08700
uniprot id: C9R936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

429009:ADEG RS00720
gene id: 429009:ADEG_RS00720
uniprot id: C9RAP1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

429009:ADEG RS07775
gene id: 429009:ADEG_RS07775
uniprot id: C9R8K7
names: Similarity
messages: Belongs to the UPF0758 family.

429009:ADEG RS01760
gene id: 429009:ADEG_RS01760
uniprot id: C9RB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS08255
gene id: 429009:ADEG_RS08255
uniprot id: C9R8V2
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS07150
gene id: 429009:ADEG_RS07150
uniprot id: C9R888
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

429009:ADEG RS07820
gene id: 429009:ADEG_RS07820
uniprot id: C9R8L5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

429009:ADEG RS00670
gene id: 429009:ADEG_RS00670
uniprot id: C9RAN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

429009:ADEG RS05140
gene id: 429009:ADEG_RS05140
uniprot id: C9RD20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

429009:ADEG RS00935
gene id: 429009:ADEG_RS00935
uniprot id: C9RAT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

429009:ADEG RS05175
gene id: 429009:ADEG_RS05175
uniprot id: C9RD27
names: Similarity
messages: Belongs to the transglycosylase Slt family.

429009:ADEG RS05610
gene id: 429009:ADEG_RS05610
uniprot id: C9RDA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

429009:ADEG RS10195
gene id: 429009:ADEG_RS10195
uniprot id: C9R9W7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

429009:ADEG RS07625
gene id: 429009:ADEG_RS07625
uniprot id: C9R8H7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

429009:ADEG RS07680
gene id: 429009:ADEG_RS07680
uniprot id: C9R8I8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

429009:ADEG RS01065
gene id: 429009:ADEG_RS01065
uniprot id: C9RAV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

429009:ADEG RS10650
gene id: 429009:ADEG_RS10650
uniprot id: C9RA59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

429009:ADEG RS02120
gene id: 429009:ADEG_RS02120
uniprot id: C9RBE5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

429009:ADEG RS11055
gene id: 429009:ADEG_RS11055
uniprot id: C9RAC0
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS04855
gene id: 429009:ADEG_RS04855
uniprot id: C9RCW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

429009:ADEG RS08180
gene id: 429009:ADEG_RS08180
uniprot id: C9R8T6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

429009:ADEG RS09560
gene id: 429009:ADEG_RS09560
uniprot id: C9R9J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

429009:ADEG RS09075
gene id: 429009:ADEG_RS09075
uniprot id: C9R9A5
names: Similarity
messages: Belongs to the acylphosphatase family.

429009:ADEG RS07910
gene id: 429009:ADEG_RS07910
uniprot id: C9R8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

429009:ADEG RS09445
gene id: 429009:ADEG_RS09445
uniprot id: C9R9H3
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS05030
gene id: 429009:ADEG_RS05030
uniprot id: C9RD00
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS01980
gene id: 429009:ADEG_RS01980
uniprot id: C9RBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

429009:ADEG RS07585
gene id: 429009:ADEG_RS07585
uniprot id: C9R8G9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

429009:ADEG RS06450
gene id: 429009:ADEG_RS06450
uniprot id: C9R7V7
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS11440
gene id: 429009:ADEG_RS11440
uniprot id: C9R9G6
names: Similarity
messages: Belongs to the phosphoribulokinase family.

429009:ADEG RS02960
gene id: 429009:ADEG_RS02960
uniprot id: C9RBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

429009:ADEG RS11235
gene id: 429009:ADEG_RS11235
uniprot id: C9RCF7
names: Similarity
messages: Belongs to the peptidase A24 family.

429009:ADEG RS09340
gene id: 429009:ADEG_RS09340
uniprot id: C9R9F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

429009:ADEG RS05545
gene id: 429009:ADEG_RS05545
uniprot id: C9RD94
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

429009:ADEG RS04485
gene id: 429009:ADEG_RS04485
uniprot id: C9RCP3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

429009:ADEG RS04940
gene id: 429009:ADEG_RS04940
uniprot id: C9RCY3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

429009:ADEG RS08735
gene id: 429009:ADEG_RS08735
uniprot id: C9R940
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

429009:ADEG RS10020
gene id: 429009:ADEG_RS10020
uniprot id: C9R9T3
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS10200
gene id: 429009:ADEG_RS10200
uniprot id: C9R9W8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS02300
gene id: 429009:ADEG_RS02300
uniprot id: C9RBI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

429009:ADEG RS10185
gene id: 429009:ADEG_RS10185
uniprot id: C9R9W5
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS05570
gene id: 429009:ADEG_RS05570
uniprot id: C9RD99
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

429009:ADEG RS01060
gene id: 429009:ADEG_RS01060
uniprot id: C9RAV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

429009:ADEG RS10695
gene id: 429009:ADEG_RS10695
uniprot id: C9RA68
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

429009:ADEG RS09885
gene id: 429009:ADEG_RS09885
uniprot id: C9R9Q6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

429009:ADEG RS07275
gene id: 429009:ADEG_RS07275
uniprot id: C9R8B1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

429009:ADEG RS10140
gene id: 429009:ADEG_RS10140
uniprot id: C9R9V6
names: Similarity
messages: Belongs to the HypD family.

429009:ADEG RS00325
gene id: 429009:ADEG_RS00325
uniprot id: C9RAD6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

429009:ADEG RS01880
gene id: 429009:ADEG_RS01880
uniprot id: C9RBA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS09540
gene id: 429009:ADEG_RS09540
uniprot id: C9R9J1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS02980
gene id: 429009:ADEG_RS02980
uniprot id: C9RBV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

429009:ADEG RS06710
gene id: 429009:ADEG_RS06710
uniprot id: C9R806
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

429009:ADEG RS02030
gene id: 429009:ADEG_RS02030
uniprot id: C9RBD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS01215
gene id: 429009:ADEG_RS01215
uniprot id: C9RAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

429009:ADEG RS09350
gene id: 429009:ADEG_RS09350
uniprot id: C9R9F7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS10470
gene id: 429009:ADEG_RS10470
uniprot id: C9RA22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

429009:ADEG RS01175
gene id: 429009:ADEG_RS01175
uniprot id: C9RAX5
names: Similarity
messages: Belongs to the manganese catalase family.

429009:ADEG RS07835
gene id: 429009:ADEG_RS07835
uniprot id: C9R8L8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

429009:ADEG RS10165
gene id: 429009:ADEG_RS10165
uniprot id: C9R9W1
names: Similarity
messages: Belongs to the peptidase A31 family.

429009:ADEG RS01265
gene id: 429009:ADEG_RS01265
uniprot id: C9RAZ1
names: Similarity
messages: Belongs to the bacterial flagellin family.

429009:ADEG RS09855
gene id: 429009:ADEG_RS09855
uniprot id: C9R9Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

429009:ADEG RS10275
gene id: 429009:ADEG_RS10275
uniprot id: C9R9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

429009:ADEG RS02910
gene id: 429009:ADEG_RS02910
uniprot id: C9RBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

429009:ADEG RS09430
gene id: 429009:ADEG_RS09430
uniprot id: C9R9H1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS03515
gene id: 429009:ADEG_RS03515
uniprot id: C9RC59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

429009:ADEG RS01000
gene id: 429009:ADEG_RS01000
uniprot id: C9RAU3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

429009:ADEG RS10875
gene id: 429009:ADEG_RS10875
uniprot id: C9RAI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

429009:ADEG RS06585
gene id: 429009:ADEG_RS06585
uniprot id: C9R7Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

429009:ADEG RS05540
gene id: 429009:ADEG_RS05540
uniprot id: C9RD93
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

429009:ADEG RS07995
gene id: 429009:ADEG_RS07995
uniprot id: C9R8Q1
names: Similarity
messages: Belongs to the universal stress protein A family.

429009:ADEG RS07490
gene id: 429009:ADEG_RS07490
uniprot id: C9R8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS07570
gene id: 429009:ADEG_RS07570
uniprot id: C9R8G6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

429009:ADEG RS05425
gene id: 429009:ADEG_RS05425
uniprot id: C9RD71
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS00825
gene id: 429009:ADEG_RS00825
uniprot id: C9RAR1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

429009:ADEG RS08770
gene id: 429009:ADEG_RS08770
uniprot id: C9R947
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

429009:ADEG RS09630
gene id: 429009:ADEG_RS09630
uniprot id: C9R9K9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

429009:ADEG RS07765
gene id: 429009:ADEG_RS07765
uniprot id: C9R8K5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

429009:ADEG RS05865
gene id: 429009:ADEG_RS05865
uniprot id: C9RDF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

429009:ADEG RS09575
gene id: 429009:ADEG_RS09575
uniprot id: C9R9J8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS07330
gene id: 429009:ADEG_RS07330
uniprot id: C9R8C1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

429009:ADEG RS00850
gene id: 429009:ADEG_RS00850
uniprot id: C9RAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

429009:ADEG RS09315
gene id: 429009:ADEG_RS09315
uniprot id: C9R9F0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

429009:ADEG RS04900
gene id: 429009:ADEG_RS04900
uniprot id: C9RCX5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS06975
gene id: 429009:ADEG_RS06975
uniprot id: C9R854
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

429009:ADEG RS05295
gene id: 429009:ADEG_RS05295
uniprot id: C9RD49
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS06965
gene id: 429009:ADEG_RS06965
uniprot id: C9R852
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

429009:ADEG RS07045
gene id: 429009:ADEG_RS07045
uniprot id: C9R868
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

429009:ADEG RS00890
gene id: 429009:ADEG_RS00890
uniprot id: C9RAS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

429009:ADEG RS03140
gene id: 429009:ADEG_RS03140
uniprot id: C9RBZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

429009:ADEG RS07705
gene id: 429009:ADEG_RS07705
uniprot id: C9R8J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

429009:ADEG RS00865
gene id: 429009:ADEG_RS00865
uniprot id: C9RAR9
names: Similarity
messages: Belongs to the universal stress protein A family.

429009:ADEG RS06610
gene id: 429009:ADEG_RS06610
uniprot id: C9R7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

429009:ADEG RS08360
gene id: 429009:ADEG_RS08360
uniprot id: C9R8X2
names: Similarity
messages: Belongs to the ribF family.

429009:ADEG RS07690
gene id: 429009:ADEG_RS07690
uniprot id: C9R8J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

429009:ADEG RS04615
gene id: 429009:ADEG_RS04615
uniprot id: C9RCR8
names: Similarity
messages: Belongs to the HdrA family.

429009:ADEG RS03065
gene id: 429009:ADEG_RS03065
uniprot id: C9RBX6
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

429009:ADEG RS05090
gene id: 429009:ADEG_RS05090
uniprot id: C9RD10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

429009:ADEG RS03935
gene id: 429009:ADEG_RS03935
uniprot id: C9RCD9
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS02170
gene id: 429009:ADEG_RS02170
uniprot id: C9RBF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

429009:ADEG RS08435
gene id: 429009:ADEG_RS08435
uniprot id: C9R8Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

429009:ADEG RS02825
gene id: 429009:ADEG_RS02825
uniprot id: C9RBS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS07710
gene id: 429009:ADEG_RS07710
uniprot id: C9R8J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

429009:ADEG RS06065
gene id: 429009:ADEG_RS06065
uniprot id: C9R7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

429009:ADEG RS11020
gene id: 429009:ADEG_RS11020
uniprot id: C9RDI4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

429009:ADEG RS04790
gene id: 429009:ADEG_RS04790
uniprot id: C9RCV3
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

429009:ADEG RS03375
gene id: 429009:ADEG_RS03375
uniprot id: C9RC30
names: Similarity
messages: Belongs to the peptidase U62 family.

429009:ADEG RS05260
gene id: 429009:ADEG_RS05260
uniprot id: C9RD42
names: Similarity
messages: Belongs to the peptidase A24 family.

429009:ADEG RS05185
gene id: 429009:ADEG_RS05185
uniprot id: C9RD29
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

429009:ADEG RS03085
gene id: 429009:ADEG_RS03085
uniprot id: C9RBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

429009:ADEG RS06220
gene id: 429009:ADEG_RS06220
uniprot id: C9R7R3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

429009:ADEG RS01840
gene id: 429009:ADEG_RS01840
uniprot id: C9RB95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

429009:ADEG RS08050
gene id: 429009:ADEG_RS08050
uniprot id: C9R8R2
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS08705
gene id: 429009:ADEG_RS08705
uniprot id: C9R937
names: Similarity
messages: Belongs to the GSP E family.

429009:ADEG RS06335
gene id: 429009:ADEG_RS06335
uniprot id: C9R7T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

429009:ADEG RS04490
gene id: 429009:ADEG_RS04490
uniprot id: C9RCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

429009:ADEG RS01225
gene id: 429009:ADEG_RS01225
uniprot id: C9RAY3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

429009:ADEG RS00395
gene id: 429009:ADEG_RS00395
uniprot id: C9RAF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

429009:ADEG RS03510
gene id: 429009:ADEG_RS03510
uniprot id: C9RC58
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

429009:ADEG RS04880
gene id: 429009:ADEG_RS04880
uniprot id: C9RCX1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

429009:ADEG RS08890
gene id: 429009:ADEG_RS08890
uniprot id: C9R969
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS00350
gene id: 429009:ADEG_RS00350
uniprot id: C9RAE1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

429009:ADEG RS00815
gene id: 429009:ADEG_RS00815
uniprot id: C9RAQ9
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

429009:ADEG RS00050
gene id: 429009:ADEG_RS00050
uniprot id: C9RA78
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

429009:ADEG RS00295
gene id: 429009:ADEG_RS00295
uniprot id: C9RAD0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

429009:ADEG RS09935
gene id: 429009:ADEG_RS09935
uniprot id: C9R9R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

429009:ADEG RS05445
gene id: 429009:ADEG_RS05445
uniprot id: C9RD75
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

429009:ADEG RS08730
gene id: 429009:ADEG_RS08730
uniprot id: C9R939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

429009:ADEG RS11030
gene id: 429009:ADEG_RS11030
uniprot id: C9RDI6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

429009:ADEG RS08335
gene id: 429009:ADEG_RS08335
uniprot id: C9R8W7
names: Similarity
messages: Belongs to the peptidase M16 family.

429009:ADEG RS03190
gene id: 429009:ADEG_RS03190
uniprot id: C9RC01
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

429009:ADEG RS01990
gene id: 429009:ADEG_RS01990
uniprot id: C9RBC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

429009:ADEG RS04585
gene id: 429009:ADEG_RS04585
uniprot id: C9RCR2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

429009:ADEG RS08925
gene id: 429009:ADEG_RS08925
uniprot id: C9R976
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

429009:ADEG RS04865
gene id: 429009:ADEG_RS04865
uniprot id: C9RCW8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

429009:ADEG RS03075
gene id: 429009:ADEG_RS03075
uniprot id: C9RBX8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

429009:ADEG RS01865
gene id: 429009:ADEG_RS01865
uniprot id: C9RB99
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

429009:ADEG RS04180
gene id: 429009:ADEG_RS04180
uniprot id: C9RCI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

429009:ADEG RS07650
gene id: 429009:ADEG_RS07650
uniprot id: C9R8I2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

429009:ADEG RS06735
gene id: 429009:ADEG_RS06735
uniprot id: C9R811
names: Similarity
messages: Belongs to the HdrA family.

429009:ADEG RS00945
gene id: 429009:ADEG_RS00945
uniprot id: C9RAT5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

429009:ADEG RS04765
gene id: 429009:ADEG_RS04765
uniprot id: C9RCU8
names: Similarity
messages: Belongs to the CobH/CbiC family.

429009:ADEG RS02905
gene id: 429009:ADEG_RS02905
uniprot id: C9RBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

429009:ADEG RS02220
gene id: 429009:ADEG_RS02220
uniprot id: C9RBG4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS04410
gene id: 429009:ADEG_RS04410
uniprot id: C9RCN1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

429009:ADEG RS01755
gene id: 429009:ADEG_RS01755
uniprot id: C9RB84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

429009:ADEG RS08040
gene id: 429009:ADEG_RS08040
uniprot id: C9R8R0
names: Similarity
messages: Belongs to the leucine-binding protein family.

429009:ADEG RS05320
gene id: 429009:ADEG_RS05320
uniprot id: C9RD54
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

429009:ADEG RS08245
gene id: 429009:ADEG_RS08245
uniprot id: C9R8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

429009:ADEG RS01590
gene id: 429009:ADEG_RS01590
uniprot id: C9RB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

429009:ADEG RS00515
gene id: 429009:ADEG_RS00515
uniprot id: C9RAK5
names: Similarity
messages: Belongs to the threonine synthase family.

429009:ADEG RS10280
gene id: 429009:ADEG_RS10280
uniprot id: C9R9Y4
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

429009:ADEG RS00560
gene id: 429009:ADEG_RS00560
uniprot id: C9RAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

429009:ADEG RS00540
gene id: 429009:ADEG_RS00540
uniprot id: C9RAL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

429009:ADEG RS01045
gene id: 429009:ADEG_RS01045
uniprot id: C9RAV1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

429009:ADEG RS07860
gene id: 429009:ADEG_RS07860
uniprot id: C9R8M3
names: Similarity
messages: Belongs to the UPF0749 family.

429009:ADEG RS07645
gene id: 429009:ADEG_RS07645
uniprot id: C9R8I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

429009:ADEG RS06470
gene id: 429009:ADEG_RS06470
uniprot id: C9R7W0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

429009:ADEG RS03395
gene id: 429009:ADEG_RS03395
uniprot id: C9RC34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

429009:ADEG RS01140
gene id: 429009:ADEG_RS01140
uniprot id: C9RAW8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS06250
gene id: 429009:ADEG_RS06250
uniprot id: C9R7R9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

429009:ADEG RS06210
gene id: 429009:ADEG_RS06210
uniprot id: C9R7R1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

429009:ADEG RS05245
gene id: 429009:ADEG_RS05245
uniprot id: C9RD39
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

429009:ADEG RS00265
gene id: 429009:ADEG_RS00265
uniprot id: C9RAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

429009:ADEG RS03380
gene id: 429009:ADEG_RS03380
uniprot id: C9RC31
names: Similarity
messages: Belongs to the peptidase U62 family.

429009:ADEG RS10190
gene id: 429009:ADEG_RS10190
uniprot id: C9R9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

429009:ADEG RS02250
gene id: 429009:ADEG_RS02250
uniprot id: C9RBH0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

429009:ADEG RS00365
gene id: 429009:ADEG_RS00365
uniprot id: C9RAE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

429009:ADEG RS05125
gene id: 429009:ADEG_RS05125
uniprot id: C9RD17
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS07740
gene id: 429009:ADEG_RS07740
uniprot id: C9R8K0
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

429009:ADEG RS01005
gene id: 429009:ADEG_RS01005
uniprot id: C9RAU4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

429009:ADEG RS03440
gene id: 429009:ADEG_RS03440
uniprot id: C9RC43
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

429009:ADEG RS05615
gene id: 429009:ADEG_RS05615
uniprot id: C9RDA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

429009:ADEG RS04365
gene id: 429009:ADEG_RS04365
uniprot id: C9RCM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

429009:ADEG RS08160
gene id: 429009:ADEG_RS08160
uniprot id: C9R8T2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

429009:ADEG RS04360
gene id: 429009:ADEG_RS04360
uniprot id: C9RCM1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

429009:ADEG RS05450
gene id: 429009:ADEG_RS05450
uniprot id: C9RD76
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

429009:ADEG RS02495
gene id: 429009:ADEG_RS02495
uniprot id: C9RBL5
names: Similarity
messages: Belongs to the peptidase S16 family.

429009:ADEG RS05840
gene id: 429009:ADEG_RS05840
uniprot id: C9RDE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

429009:ADEG RS09505
gene id: 429009:ADEG_RS09505
uniprot id: C9R9I5
names: Similarity
messages: Belongs to the DHPS family.

429009:ADEG RS08225
gene id: 429009:ADEG_RS08225
uniprot id: C9R8U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

429009:ADEG RS03010
gene id: 429009:ADEG_RS03010
uniprot id: C9RBW5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

429009:ADEG RS00995
gene id: 429009:ADEG_RS00995
uniprot id: C9RAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

429009:ADEG RS01735
gene id: 429009:ADEG_RS01735
uniprot id: C9RB80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

429009:ADEG RS10320
gene id: 429009:ADEG_RS10320
uniprot id: C9R9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

429009:ADEG RS04815
gene id: 429009:ADEG_RS04815
uniprot id: C9RCV9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

429009:ADEG RS10505
gene id: 429009:ADEG_RS10505
uniprot id: C9RA29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

429009:ADEG RS05290
gene id: 429009:ADEG_RS05290
uniprot id: C9RD48
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS03970
gene id: 429009:ADEG_RS03970
uniprot id: C9RCE6
names: Similarity
messages: Belongs to the GSP E family.

429009:ADEG RS05565
gene id: 429009:ADEG_RS05565
uniprot id: C9RD98
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

429009:ADEG RS06365
gene id: 429009:ADEG_RS06365
uniprot id: C9R7U0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

429009:ADEG RS08750
gene id: 429009:ADEG_RS08750
uniprot id: C9R943
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

429009:ADEG RS04560
gene id: 429009:ADEG_RS04560
uniprot id: C9RCQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

429009:ADEG RS00145
gene id: 429009:ADEG_RS00145
uniprot id: C9RAA1
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS00070
gene id: 429009:ADEG_RS00070
uniprot id: C9RA80
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

429009:ADEG RS10045
gene id: 429009:ADEG_RS10045
uniprot id: C9R9T7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS01160
gene id: 429009:ADEG_RS01160
uniprot id: C9RAX2
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

429009:ADEG RS08355
gene id: 429009:ADEG_RS08355
uniprot id: C9R8X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

429009:ADEG RS07245
gene id: 429009:ADEG_RS07245
uniprot id: C9R8A5
names: Similarity
messages: Belongs to the transpeptidase family.

429009:ADEG RS07695
gene id: 429009:ADEG_RS07695
uniprot id: C9R8J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

429009:ADEG RS01925
gene id: 429009:ADEG_RS01925
uniprot id: C9RBB1
names: Similarity
messages: Belongs to the glutamate synthase family.

429009:ADEG RS04385
gene id: 429009:ADEG_RS04385
uniprot id: C9RCM6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

429009:ADEG RS00155
gene id: 429009:ADEG_RS00155
uniprot id: C9RAA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

429009:ADEG RS01400
gene id: 429009:ADEG_RS01400
uniprot id: C9RB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

429009:ADEG RS03215
gene id: 429009:ADEG_RS03215
uniprot id: C9RC06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

429009:ADEG RS05675
gene id: 429009:ADEG_RS05675
uniprot id: C9RDB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

429009:ADEG RS08230
gene id: 429009:ADEG_RS08230
uniprot id: C9R8U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

429009:ADEG RS05190
gene id: 429009:ADEG_RS05190
uniprot id: C9RD30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

429009:ADEG RS08095
gene id: 429009:ADEG_RS08095
uniprot id: C9R8S1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

429009:ADEG RS07030
gene id: 429009:ADEG_RS07030
uniprot id: C9R865
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS04275
gene id: 429009:ADEG_RS04275
uniprot id: C9RCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

429009:ADEG RS10870
gene id: 429009:ADEG_RS10870
uniprot id: C9RAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

429009:ADEG RS10330
gene id: 429009:ADEG_RS10330
uniprot id: C9R9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

429009:ADEG RS06340
gene id: 429009:ADEG_RS06340
uniprot id: C9R7T5
names: Similarity
messages: Belongs to the Ahb/Nir family.

429009:ADEG RS03080
gene id: 429009:ADEG_RS03080
uniprot id: C9RBX9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

429009:ADEG RS09995
gene id: 429009:ADEG_RS09995
uniprot id: C9R9S8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

429009:ADEG RS07520
gene id: 429009:ADEG_RS07520
uniprot id: C9R8F6
names: Similarity
messages: Belongs to the leucine-binding protein family.

429009:ADEG RS02975
gene id: 429009:ADEG_RS02975
uniprot id: C9RBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

429009:ADEG RS06230
gene id: 429009:ADEG_RS06230
uniprot id: C9R7R5
names: Similarity
messages: Belongs to the peptidase A31 family.

429009:ADEG RS03050
gene id: 429009:ADEG_RS03050
uniprot id: C9RBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

429009:ADEG RS05220
gene id: 429009:ADEG_RS05220
uniprot id: C9RD34
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS11090
gene id: 429009:ADEG_RS11090
uniprot id: C9RAZ0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

429009:ADEG RS10350
gene id: 429009:ADEG_RS10350
uniprot id: C9R9Z8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

429009:ADEG RS10480
gene id: 429009:ADEG_RS10480
uniprot id: C9RA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

429009:ADEG RS08185
gene id: 429009:ADEG_RS08185
uniprot id: C9R8T7
names: Similarity
messages: Belongs to the GPI family.

429009:ADEG RS06430
gene id: 429009:ADEG_RS06430
uniprot id: C9R7V3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

429009:ADEG RS07560
gene id: 429009:ADEG_RS07560
uniprot id: C9R8G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

429009:ADEG RS09725
gene id: 429009:ADEG_RS09725
uniprot id: C9R9M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

429009:ADEG RS03070
gene id: 429009:ADEG_RS03070
uniprot id: C9RBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

429009:ADEG RS02930
gene id: 429009:ADEG_RS02930
uniprot id: C9RBU9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

429009:ADEG RS07170
gene id: 429009:ADEG_RS07170
uniprot id: C9R892
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

429009:ADEG RS07175
gene id: 429009:ADEG_RS07175
uniprot id: C9R893
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

429009:ADEG RS08150
gene id: 429009:ADEG_RS08150
uniprot id: C9R8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

429009:ADEG RS05535
gene id: 429009:ADEG_RS05535
uniprot id: C9RD92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS05745
gene id: 429009:ADEG_RS05745
uniprot id: C9RDC8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

429009:ADEG RS06150
gene id: 429009:ADEG_RS06150
uniprot id: C9R7P7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

429009:ADEG RS07555
gene id: 429009:ADEG_RS07555
uniprot id: C9R8G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

429009:ADEG RS07405
gene id: 429009:ADEG_RS07405
uniprot id: C9R8D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

429009:ADEG RS03635
gene id: 429009:ADEG_RS03635
uniprot id: C9RC82
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

429009:ADEG RS06545
gene id: 429009:ADEG_RS06545
uniprot id: C9R7X4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

429009:ADEG RS10030
gene id: 429009:ADEG_RS10030
uniprot id: C9R9T5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

429009:ADEG RS02340
gene id: 429009:ADEG_RS02340
uniprot id: C9RBI7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS06875
gene id: 429009:ADEG_RS06875
uniprot id: C9R835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

429009:ADEG RS10735
gene id: 429009:ADEG_RS10735
uniprot id: C9RAF9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

429009:ADEG RS05155
gene id: 429009:ADEG_RS05155
uniprot id: C9RD23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

429009:ADEG RS05790
gene id: 429009:ADEG_RS05790
uniprot id: C9RDD7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

429009:ADEG RS09705
gene id: 429009:ADEG_RS09705
uniprot id: C9R9M3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

429009:ADEG RS00800
gene id: 429009:ADEG_RS00800
uniprot id: C9RAQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

429009:ADEG RS06205
gene id: 429009:ADEG_RS06205
uniprot id: C9R7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

429009:ADEG RS00895
gene id: 429009:ADEG_RS00895
uniprot id: C9RAS5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

429009:ADEG RS06645
gene id: 429009:ADEG_RS06645
uniprot id: C9R7Z3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS09840
gene id: 429009:ADEG_RS09840
uniprot id: C9R9P9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS02685
gene id: 429009:ADEG_RS02685
uniprot id: C9RBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS09740
gene id: 429009:ADEG_RS09740
uniprot id: C9R9N0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

429009:ADEG RS05170
gene id: 429009:ADEG_RS05170
uniprot id: C9RD26
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

429009:ADEG RS07505
gene id: 429009:ADEG_RS07505
uniprot id: C9R8F3
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS10400
gene id: 429009:ADEG_RS10400
uniprot id: C9RA08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS00740
gene id: 429009:ADEG_RS00740
uniprot id: C9RAP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

429009:ADEG RS10680
gene id: 429009:ADEG_RS10680
uniprot id: C9RA65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

429009:ADEG RS01125
gene id: 429009:ADEG_RS01125
uniprot id: C9RAW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS09215
gene id: 429009:ADEG_RS09215
uniprot id: C9R9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

429009:ADEG RS09455
gene id: 429009:ADEG_RS09455
uniprot id: C9R9H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

429009:ADEG RS05850
gene id: 429009:ADEG_RS05850
uniprot id: C9RDE9
names: Similarity
messages: Belongs to the TrpC family.

429009:ADEG RS07265
gene id: 429009:ADEG_RS07265
uniprot id: C9R8A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

429009:ADEG RS01295
gene id: 429009:ADEG_RS01295
uniprot id: C9RAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

429009:ADEG RS06345
gene id: 429009:ADEG_RS06345
uniprot id: C9R7T6
names: Similarity
messages: Belongs to the Ahb/Nir family.

429009:ADEG RS08895
gene id: 429009:ADEG_RS08895
uniprot id: C9R970
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

429009:ADEG RS09775
gene id: 429009:ADEG_RS09775
uniprot id: C9R9N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS00880
gene id: 429009:ADEG_RS00880
uniprot id: C9RAS2
names: Similarity
messages: Belongs to the peptidase S16 family.

429009:ADEG RS07545
gene id: 429009:ADEG_RS07545
uniprot id: C9R8G1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

429009:ADEG RS07080
gene id: 429009:ADEG_RS07080
uniprot id: C9R875
names: Similarity
messages: Belongs to the UPF0251 family.

429009:ADEG RS07975
gene id: 429009:ADEG_RS07975
uniprot id: C9R8P7
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS11345
gene id: 429009:ADEG_RS11345
uniprot id: C9R7Y4
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS09835
gene id: 429009:ADEG_RS09835
uniprot id: C9R9P8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

429009:ADEG RS06530
gene id: 429009:ADEG_RS06530
uniprot id: C9R7X1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

429009:ADEG RS09530
gene id: 429009:ADEG_RS09530
uniprot id: C9R9I9
names: Similarity
messages: Belongs to the P(II) protein family.

429009:ADEG RS08745
gene id: 429009:ADEG_RS08745
uniprot id: C9R942
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

429009:ADEG RS00870
gene id: 429009:ADEG_RS00870
uniprot id: C9RAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS07670
gene id: 429009:ADEG_RS07670
uniprot id: C9R8I6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

429009:ADEG RS00160
gene id: 429009:ADEG_RS00160
uniprot id: C9RAA4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

429009:ADEG RS01940
gene id: 429009:ADEG_RS01940
uniprot id: C9RBB4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

429009:ADEG RS00925
gene id: 429009:ADEG_RS00925
uniprot id: C9RAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

429009:ADEG RS12410
gene id: 429009:ADEG_RS12410
uniprot id: C9RC04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

429009:ADEG RS09755
gene id: 429009:ADEG_RS09755
uniprot id: C9R9N3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

429009:ADEG RS09375
gene id: 429009:ADEG_RS09375
uniprot id: C9R9G1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

429009:ADEG RS03420
gene id: 429009:ADEG_RS03420
uniprot id: C9RC39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

429009:ADEG RS00610
gene id: 429009:ADEG_RS00610
uniprot id: C9RAM1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

429009:ADEG RS04495
gene id: 429009:ADEG_RS04495
uniprot id: C9RCP5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

429009:ADEG RS09720
gene id: 429009:ADEG_RS09720
uniprot id: C9R9M6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

429009:ADEG RS09090
gene id: 429009:ADEG_RS09090
uniprot id: C9R9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS01890
gene id: 429009:ADEG_RS01890
uniprot id: C9RBA4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS00685
gene id: 429009:ADEG_RS00685
uniprot id: C9RAN5
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS01600
gene id: 429009:ADEG_RS01600
uniprot id: C9RB54
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

429009:ADEG RS06355
gene id: 429009:ADEG_RS06355
uniprot id: C9R7T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

429009:ADEG RS03220
gene id: 429009:ADEG_RS03220
uniprot id: C9RC07
names: Similarity
messages: Belongs to the UPF0751 family.

429009:ADEG RS10260
gene id: 429009:ADEG_RS10260
uniprot id: C9R9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

429009:ADEG RS00750
gene id: 429009:ADEG_RS00750
uniprot id: C9RAP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity.

429009:ADEG RS00340
gene id: 429009:ADEG_RS00340
uniprot id: C9RAD9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

429009:ADEG RS09690
gene id: 429009:ADEG_RS09690
uniprot id: C9R9M0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

429009:ADEG RS10395
gene id: 429009:ADEG_RS10395
uniprot id: C9RA07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

429009:ADEG RS07040
gene id: 429009:ADEG_RS07040
uniprot id: C9R867
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

429009:ADEG RS01245
gene id: 429009:ADEG_RS01245
uniprot id: C9RAY7
names: Similarity
messages: Belongs to the FlgM family.

429009:ADEG RS02130
gene id: 429009:ADEG_RS02130
uniprot id: C9RBE6
names: Similarity
messages: Belongs to the UPF0236 family.

429009:ADEG RS01105
gene id: 429009:ADEG_RS01105
uniprot id: C9RAW3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

429009:ADEG RS07105
gene id: 429009:ADEG_RS07105
uniprot id: C9R879
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

429009:ADEG RS04370
gene id: 429009:ADEG_RS04370
uniprot id: C9RCM3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

429009:ADEG RS10515
gene id: 429009:ADEG_RS10515
uniprot id: C9RA31
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

429009:ADEG RS09385
gene id: 429009:ADEG_RS09385
uniprot id: C9R9G3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS06235
gene id: 429009:ADEG_RS06235
uniprot id: C9R7R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS03165
gene id: 429009:ADEG_RS03165
uniprot id: C9RBZ6
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

429009:ADEG RS00260
gene id: 429009:ADEG_RS00260
uniprot id: C9RAC3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

429009:ADEG RS08200
gene id: 429009:ADEG_RS08200
uniprot id: C9R8U0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

429009:ADEG RS09700
gene id: 429009:ADEG_RS09700
uniprot id: C9R9M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

429009:ADEG RS00860
gene id: 429009:ADEG_RS00860
uniprot id: C9RAR8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

429009:ADEG RS00205
gene id: 429009:ADEG_RS00205
uniprot id: C9RAB2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

429009:ADEG RS05530
gene id: 429009:ADEG_RS05530
uniprot id: C9RD91
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

429009:ADEG RS08165
gene id: 429009:ADEG_RS08165
uniprot id: C9R8T3
names: Similarity
messages: Belongs to the sigma-54 factor family.

429009:ADEG RS00380
gene id: 429009:ADEG_RS00380
uniprot id: C9RAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

429009:ADEG RS07655
gene id: 429009:ADEG_RS07655
uniprot id: C9R8I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

429009:ADEG RS05600
gene id: 429009:ADEG_RS05600
uniprot id: C9RDA5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

429009:ADEG RS09055
gene id: 429009:ADEG_RS09055
uniprot id: C9R9A1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

429009:ADEG RS00790
gene id: 429009:ADEG_RS00790
uniprot id: C9RAQ4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

429009:ADEG RS09715
gene id: 429009:ADEG_RS09715
uniprot id: C9R9M5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

429009:ADEG RS00620
gene id: 429009:ADEG_RS00620
uniprot id: C9RAM3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

429009:ADEG RS07055
gene id: 429009:ADEG_RS07055
uniprot id: C9R870
names: Similarity
messages: Belongs to the TlyA family.

429009:ADEG RS09220
gene id: 429009:ADEG_RS09220
uniprot id: C9R9D2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

429009:ADEG RS08740
gene id: 429009:ADEG_RS08740
uniprot id: C9R941
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

429009:ADEG RS01135
gene id: 429009:ADEG_RS01135
uniprot id: C9RAW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

429009:ADEG RS02830
gene id: 429009:ADEG_RS02830
uniprot id: C9RBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS07980
gene id: 429009:ADEG_RS07980
uniprot id: C9R8P8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

429009:ADEG RS05845
gene id: 429009:ADEG_RS05845
uniprot id: C9RDE8
names: Similarity
messages: Belongs to the TrpF family.

429009:ADEG RS01580
gene id: 429009:ADEG_RS01580
uniprot id: C9RB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

429009:ADEG RS03385
gene id: 429009:ADEG_RS03385
uniprot id: C9RC32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

429009:ADEG RS03265
gene id: 429009:ADEG_RS03265
uniprot id: C9RC13
names: Similarity
messages: Belongs to the UPF0236 family.

429009:ADEG RS07315
gene id: 429009:ADEG_RS07315
uniprot id: C9R8B8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

429009:ADEG RS00470
gene id: 429009:ADEG_RS00470
uniprot id: C9RAJ7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

429009:ADEG RS01070
gene id: 429009:ADEG_RS01070
uniprot id: C9RAV6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

429009:ADEG RS02595
gene id: 429009:ADEG_RS02595
uniprot id: C9RBN4
names: Similarity
messages: Belongs to the UPF0236 family.

429009:ADEG RS04735
gene id: 429009:ADEG_RS04735
uniprot id: C9RCU2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

429009:ADEG RS07325
gene id: 429009:ADEG_RS07325
uniprot id: C9R8C0
names: Similarity
messages: Belongs to the UbiD family.

429009:ADEG RS04775
gene id: 429009:ADEG_RS04775
uniprot id: C9RCV0
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS05100
gene id: 429009:ADEG_RS05100
uniprot id: C9RD12
names: Similarity
messages: Belongs to the AOR/FOR family.

429009:ADEG RS07810
gene id: 429009:ADEG_RS07810
uniprot id: C9R8L3
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

429009:ADEG RS08155
gene id: 429009:ADEG_RS08155
uniprot id: C9R8T1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

429009:ADEG RS02510
gene id: 429009:ADEG_RS02510
uniprot id: C9RBL8
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

429009:ADEG RS07970
gene id: 429009:ADEG_RS07970
uniprot id: C9R8P6
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

429009:ADEG RS04295
gene id: 429009:ADEG_RS04295
uniprot id: C9RCK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

429009:ADEG RS10465
gene id: 429009:ADEG_RS10465
uniprot id: C9RA21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

429009:ADEG RS12145
gene id: 429009:ADEG_RS12145
uniprot id: C9RCD2
names: Similarity
messages: Belongs to the peptidase A24 family.

429009:ADEG RS02265
gene id: 429009:ADEG_RS02265
uniprot id: C9RBH3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

429009:ADEG RS02425
gene id: 429009:ADEG_RS02425
uniprot id: C9RBK4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

429009:ADEG RS08020
gene id: 429009:ADEG_RS08020
uniprot id: C9R8Q6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

429009:ADEG RS01520
gene id: 429009:ADEG_RS01520
uniprot id: C9RB37
names: Similarity
messages: Belongs to the class-I fumarase family.

429009:ADEG RS07370
gene id: 429009:ADEG_RS07370
uniprot id: C9R8C8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

429009:ADEG RS02780
gene id: 429009:ADEG_RS02780
uniprot id: C9RBS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

429009:ADEG RS07465
gene id: 429009:ADEG_RS07465
uniprot id: C9R8E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

429009:ADEG RS00030
gene id: 429009:ADEG_RS00030
uniprot id: C9RA74
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

429009:ADEG RS06970
gene id: 429009:ADEG_RS06970
uniprot id: C9R853
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

429009:ADEG RS00010
gene id: 429009:ADEG_RS00010
uniprot id: C9RA70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

429009:ADEG RS07460
gene id: 429009:ADEG_RS07460
uniprot id: C9R8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

429009:ADEG RS07400
gene id: 429009:ADEG_RS07400
uniprot id: C9R8D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

429009:ADEG RS02280
gene id: 429009:ADEG_RS02280
uniprot id: C9RBH6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

429009:ADEG RS00840
gene id: 429009:ADEG_RS00840
uniprot id: C9RAR4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

429009:ADEG RS01900
gene id: 429009:ADEG_RS01900
uniprot id: C9RBA6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

429009:ADEG RS00920
gene id: 429009:ADEG_RS00920
uniprot id: C9RAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

429009:ADEG RS09405
gene id: 429009:ADEG_RS09405
uniprot id: C9R9G7
names: Similarity
messages: Belongs to the RuBisCO large chain family.

429009:ADEG RS04870
gene id: 429009:ADEG_RS04870
uniprot id: C9RCW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

429009:ADEG RS01505
gene id: 429009:ADEG_RS01505
uniprot id: C9RB34
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

429009:ADEG RS01055
gene id: 429009:ADEG_RS01055
uniprot id: C9RAV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

429009:ADEG RS06420
gene id: 429009:ADEG_RS06420
uniprot id: C9R7V1
names: Similarity
messages: Belongs to the UPF0237 family.

429009:ADEG RS01210
gene id: 429009:ADEG_RS01210
uniprot id: C9RAY0
names: Similarity
messages: Belongs to the MotB family.

429009:ADEG RS10375
gene id: 429009:ADEG_RS10375
uniprot id: C9RA03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

429009:ADEG RS09910
gene id: 429009:ADEG_RS09910
uniprot id: C9R9R1
names: Subcellular Location Annotation
messages: Membrane

429009:ADEG RS01165
gene id: 429009:ADEG_RS01165
uniprot id: C9RAX3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

429009:ADEG RS09425
gene id: 429009:ADEG_RS09425
uniprot id: C9R9H0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

429009:ADEG RS05870
gene id: 429009:ADEG_RS05870
uniprot id: C9RDF3
names: Similarity
messages: Belongs to the UPF0236 family.

429009:ADEG RS07960
gene id: 429009:ADEG_RS07960
uniprot id: C9R8P4
names: Similarity
messages: Belongs to the UPF0045 family.

429009:ADEG RS01810
gene id: 429009:ADEG_RS01810
uniprot id: C9RB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

429009:ADEG RS08620
gene id: 429009:ADEG_RS08620
uniprot id: C9R920
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

429009:ADEG RS03170
gene id: 429009:ADEG_RS03170
uniprot id: C9RBZ7
names: Similarity
messages: Belongs to the CinA family.

429009:ADEG RS02860
gene id: 429009:ADEG_RS02860
uniprot id: C9RBT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

429009:ADEG RS07615
gene id: 429009:ADEG_RS07615
uniprot id: C9R8H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

429009:ADEG RS08005
gene id: 429009:ADEG_RS08005
uniprot id: C9R8Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

429009:ADEG RS05805
gene id: 429009:ADEG_RS05805
uniprot id: C9RDE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

429009:ADEG RS01905
gene id: 429009:ADEG_RS01905
uniprot id: C9RBA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.