42514:nlgn2b
gene id: 42514:nlgn2b
uniprot id: A0A3B4EGJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

42514:atf1
gene id: 42514:atf1
uniprot id: A0A3B4CBL3
names: Subcellular Location Annotation
messages: Nucleus

42514:esrra
gene id: 42514:esrra
uniprot id: A0A3B4DR14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

42514:sec61g
gene id: 42514:sec61g
uniprot id: A0A3B4CLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:pgap1
gene id: 42514:pgap1
uniprot id: A0A3B4DJT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

42514:pelo
gene id: 42514:pelo
uniprot id: A0A3B4DVR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

42514:LOC108435101
gene id: 42514:LOC108435101
uniprot id: A0A3B4C6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:zc3hc1
gene id: 42514:zc3hc1
uniprot id: A0A3B4CTW1
names: Subcellular Location Annotation
messages: Nucleus

42514:pus7l
gene id: 42514:pus7l
uniprot id: A0A3B4D3N2
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

42514:lrrc8c
gene id: 42514:lrrc8c
uniprot id: A0A3B4BT05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

42514:fam189b
gene id: 42514:fam189b
uniprot id: A0A3B4EM77
names: Similarity
messages: Belongs to the ENTREP family.

42514:spry1
gene id: 42514:spry1
uniprot id: A0A3B4D135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

42514:ppp5c
gene id: 42514:ppp5c
uniprot id: A0A3B4BTC9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

42514:thrb
gene id: 42514:thrb
uniprot id: A0A3B4DL61
uniprot id: A0A3B4DNU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

42514:ptprea
gene id: 42514:ptprea
uniprot id: A0A3B4C747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

42514:slc22a21
gene id: 42514:slc22a21
uniprot id: A0A3B4CCQ7
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

42514:lim2.3
gene id: 42514:lim2.3
uniprot id: A0A3B4C7C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

42514:p4ha1a
gene id: 42514:p4ha1a
uniprot id: A0A3B4EIK4
uniprot id: A0A3B4EJW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

42514:alg11
gene id: 42514:alg11
uniprot id: A0A3B4DMT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

42514:LOC108433575
gene id: 42514:LOC108433575
uniprot id: A0A3B4E3A4
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:sod2
gene id: 42514:sod2
uniprot id: A0A3B4E9A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

42514:usp7
gene id: 42514:usp7
uniprot id: A0A3B4ED22
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:pyyb
gene id: 42514:pyyb
uniprot id: A0A1I9HVY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

42514:npnta
gene id: 42514:npnta
uniprot id: A0A3B4CNF9
uniprot id: A0A3B4CQC5
uniprot id: A0A3B4E9B1
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dock4
gene id: 42514:dock4
uniprot id: A0A3B4CMH5
names: Similarity
messages: Belongs to the DOCK family.

42514:nr0b1
gene id: 42514:nr0b1
uniprot id: A0A3B4CAF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus

42514:golph3l
gene id: 42514:golph3l
uniprot id: A0A3B4E834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

42514:ttc26
gene id: 42514:ttc26
uniprot id: A0A3B4D7R7
names: Similarity
messages: Belongs to the IFT56 family.

42514:fam83hb
gene id: 42514:fam83hb
uniprot id: A0A3B4EJ42
names: Similarity
messages: Belongs to the FAM83 family.

42514:selenbp1
gene id: 42514:selenbp1
uniprot id: A0A3B4D458
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

42514:trpt1
gene id: 42514:trpt1
uniprot id: A0A3B4BR18
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

42514:rnft1
gene id: 42514:rnft1
uniprot id: A0A3B4DSD7
names: Subcellular Location Annotation
messages: Membrane

42514:galnt11
gene id: 42514:galnt11
uniprot id: A0A3B4DFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:nr1d4a
gene id: 42514:nr1d4a
uniprot id: A0A3B4EBY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

42514:LOC108416127
gene id: 42514:LOC108416127
uniprot id: A0A3B4CNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

42514:mtnr1al
gene id: 42514:mtnr1al
uniprot id: A0A3B4EIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity.
messages: Membrane

42514:dkk1a
gene id: 42514:dkk1a
uniprot id: A0A3B4ERP9
names: Similarity
messages: Belongs to the dickkopf family.

42514:LOC108429433
gene id: 42514:LOC108429433
uniprot id: A0A3B4D7U1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

42514:LOC108434337
gene id: 42514:LOC108434337
uniprot id: A0A3B4DKT3
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

42514:cplx3b
gene id: 42514:cplx3b
uniprot id: A0A3B4E2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

42514:LOC108443674
gene id: 42514:LOC108443674
uniprot id: A0A3B4BX73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

42514:pcxa
gene id: 42514:pcxa
uniprot id: A0A3B4CQJ7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

42514:alas2
gene id: 42514:alas2
uniprot id: A0A3B4D8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

42514:ror1
gene id: 42514:ror1
uniprot id: A0A3B4DK10
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:phka1a
gene id: 42514:phka1a
uniprot id: A0A3B4CPC2
uniprot id: A0A3B4CT46
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

42514:abcg5
gene id: 42514:abcg5
uniprot id: A0A3B4C883
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

42514:cldn7a
gene id: 42514:cldn7a
uniprot id: A0A3B4DWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:adi1
gene id: 42514:adi1
uniprot id: A0A3B4C0X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

42514:rrp15
gene id: 42514:rrp15
uniprot id: A0A3B4C4Z5
names: Similarity
messages: Belongs to the RRP15 family.

42514:zic5
gene id: 42514:zic5
uniprot id: A0A3B4CZ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

42514:psmb2
gene id: 42514:psmb2
uniprot id: A0A3B4EFY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

42514:afmid
gene id: 42514:afmid
uniprot id: A0A3B4D1N6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

42514:LOC108436105
gene id: 42514:LOC108436105
uniprot id: A0A3B4CYB8
names: Subcellular Location Annotation
messages: Membrane

42514:faah2a
gene id: 42514:faah2a
uniprot id: A0A3B4C9T2
names: Similarity
messages: Belongs to the amidase family.

42514:iqcg
gene id: 42514:iqcg
uniprot id: A0A3B4DEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC9 family.
messages: flagellum
messages: flagellum axoneme

42514:plcd4b
gene id: 42514:plcd4b
uniprot id: A0A3B4C8M5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus

42514:cops4
gene id: 42514:cops4
uniprot id: A0A3B4BZ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

42514:mtx3
gene id: 42514:mtx3
uniprot id: A0A3B4ENL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:med8
gene id: 42514:med8
uniprot id: A0A3B4BLN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
messages: Component of the Mediator complex.
messages: Nucleus

42514:ptges3a
gene id: 42514:ptges3a
uniprot id: A0A3B4EG63
names: Similarity
messages: Belongs to the p23/wos2 family.

42514:cnrip1b
gene id: 42514:cnrip1b
uniprot id: A0A3B4EIQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

42514:desi1a
gene id: 42514:desi1a
uniprot id: A0A3B4E8F6
names: Similarity
messages: Belongs to the DeSI family.

42514:slc8b1
gene id: 42514:slc8b1
uniprot id: A0A3B4D7T7
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108444315
gene id: 42514:LOC108444315
uniprot id: A0A3B4C0T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:cd82a
gene id: 42514:cd82a
uniprot id: A0A3B4CEN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:slc17a7b
gene id: 42514:slc17a7b
uniprot id: A0A3B4BTV6
names: Subcellular Location Annotation
messages: Membrane

42514:abcg4a
gene id: 42514:abcg4a
uniprot id: A0A3B4DS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

42514:cebpa
gene id: 42514:cebpa
uniprot id: A0A3B4EG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

42514:ccdc124
gene id: 42514:ccdc124
uniprot id: A0A3B4EJF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

42514:fnbp1l
gene id: 42514:fnbp1l
uniprot id: A0A3B4CLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Vesicle
messages: cell cortex

42514:esyt3
gene id: 42514:esyt3
uniprot id: A0A3B4DDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:ak4
gene id: 42514:ak4
uniprot id: A0A3B4DHX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

42514:dpy30
gene id: 42514:dpy30
uniprot id: A0A3B4E0B8
names: Similarity
messages: Belongs to the dpy-30 family.

42514:asf1ba
gene id: 42514:asf1ba
uniprot id: A0A3B4CCT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

42514:mylkb
gene id: 42514:mylkb
uniprot id: A0A3B4ED00
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

42514:LOC108413915
gene id: 42514:LOC108413915
uniprot id: A0A3B4CX51
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

42514:LOC108410583
gene id: 42514:LOC108410583
uniprot id: A0A3B4E8W5
names: Similarity
messages: Belongs to the IAP family.

42514:clic1
gene id: 42514:clic1
uniprot id: A0A3B4CBR0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

42514:LOC108414117
gene id: 42514:LOC108414117
uniprot id: A0A3B4DEE0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cul2
gene id: 42514:cul2
uniprot id: A0A3B4DIT9
names: Similarity
messages: Belongs to the cullin family.

42514:fam114a1
gene id: 42514:fam114a1
uniprot id: A0A3B4CG70
names: Similarity
messages: Belongs to the FAM114 family.

42514:LOC108439741
gene id: 42514:LOC108439741
uniprot id: A0A3B4C198
uniprot id: A0A3B4DUC5
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

42514:tk1
gene id: 42514:tk1
uniprot id: A0A3B4CXC8
names: Similarity
messages: Belongs to the thymidine kinase family.

42514:cct3
gene id: 42514:cct3
uniprot id: A0A3B4DE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

42514:brf1b
gene id: 42514:brf1b
uniprot id: A0A3B4BQG9
uniprot id: A0A3B4BQS1
names: Similarity
messages: Belongs to the TFIIB family.

42514:sgo1
gene id: 42514:sgo1
uniprot id: A0A3B4C481
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

42514:ddx52
gene id: 42514:ddx52
uniprot id: A0A3B4CB16
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

42514:rps27.1
gene id: 42514:rps27.1
uniprot id: A0A3B4CM81
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

42514:wars1
gene id: 42514:wars1
uniprot id: A0A3B4DVE6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:amfra
gene id: 42514:amfra
uniprot id: A0A3B4DHP1
names: Subcellular Location Annotation
messages: Membrane

42514:pard6a
gene id: 42514:pard6a
uniprot id: A0A3B4CIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

42514:ccnh
gene id: 42514:ccnh
uniprot id: A0A3B4D577
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

42514:dhrs7b
gene id: 42514:dhrs7b
uniprot id: A0A3B4C7Q8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:rdh8a
gene id: 42514:rdh8a
uniprot id: A0A3B4E2T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

42514:cpxm1a
gene id: 42514:cpxm1a
uniprot id: A0A3B4CMB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

42514:LOC108432182
gene id: 42514:LOC108432182
uniprot id: A0A3B4DHD9
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:uvssa
gene id: 42514:uvssa
uniprot id: A0A3B4CNA5
names: Similarity
messages: Belongs to the UVSSA family.

42514:rdh5
gene id: 42514:rdh5
uniprot id: A0A3B4EPU4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:xk
gene id: 42514:xk
uniprot id: A0A3B4C6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:cdh7a
gene id: 42514:cdh7a
uniprot id: A0A3B4CWI2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:kifbp
gene id: 42514:kifbp
uniprot id: A0A3B4EHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

42514:med19b
gene id: 42514:med19b
uniprot id: A0A3B4DNA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:ltb4r2a
gene id: 42514:ltb4r2a
uniprot id: A0A3B4C0L6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:ube2d1a
gene id: 42514:ube2d1a
uniprot id: A0A3B4D9Z1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:sf1
gene id: 42514:sf1
uniprot id: A0A3B4DX43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

42514:phyhiplb
gene id: 42514:phyhiplb
uniprot id: A0A3B4CPA7
uniprot id: A0A3B4E8L7
names: Similarity
messages: Belongs to the PHYHIP family.

42514:fabp3
gene id: 42514:fabp3
uniprot id: A0A3B4D6R0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:casr
gene id: 42514:casr
uniprot id: A0A3B4BLA2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:hs3st1l2
gene id: 42514:hs3st1l2
uniprot id: A0A3B4E964
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:tcea1
gene id: 42514:tcea1
uniprot id: A0A3B4CME2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

42514:LOC108438708
gene id: 42514:LOC108438708
uniprot id: A0A3B4BVS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

42514:slc6a14
gene id: 42514:slc6a14
uniprot id: A0A3B4C0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:LOC108430263
gene id: 42514:LOC108430263
uniprot id: A0A3B4BV37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

42514:zdhhc5a
gene id: 42514:zdhhc5a
uniprot id: A0A3B4BUH9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:npb
gene id: 42514:npb
uniprot id: A0A3B4EEG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

42514:tjp2a
gene id: 42514:tjp2a
uniprot id: A0A3B4D869
uniprot id: A0A3B4D9A5
uniprot id: A0A3B4EHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:prkcda
gene id: 42514:prkcda
uniprot id: A0A3B4CHJ9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

42514:ndufs2
gene id: 42514:ndufs2
uniprot id: A0A3B4E6F4
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

42514:hyal1
gene id: 42514:hyal1
uniprot id: A0A3B4C4E7
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

42514:gys1
gene id: 42514:gys1
uniprot id: A0A3B4C1N9
uniprot id: A0A3B4DU95
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

42514:laptm4b
gene id: 42514:laptm4b
uniprot id: A0A3B4DT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

42514:sypa
gene id: 42514:sypa
uniprot id: A0A3B4C2U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:ppp3cca
gene id: 42514:ppp3cca
uniprot id: A0A3B4CZV4
uniprot id: A0A3B4EDY9
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

42514:LOC108442945
gene id: 42514:LOC108442945
uniprot id: A0A3B4E3H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

42514:LOC108427721
gene id: 42514:LOC108427721
uniprot id: A0A3B4EDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:hmga1b
gene id: 42514:hmga1b
uniprot id: A0A3B4C4H9
names: Similarity
messages: Belongs to the HMGA family.

42514:slc16a2
gene id: 42514:slc16a2
uniprot id: A0A3B4CWB3
names: Subcellular Location Annotation
messages: Membrane

42514:wnt3
gene id: 42514:wnt3
uniprot id: A0A3B4C0Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:vgll2b
gene id: 42514:vgll2b
uniprot id: A0A3B4C4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

42514:plrg1
gene id: 42514:plrg1
uniprot id: A0A3B4CTZ8
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

42514:mb21d2
gene id: 42514:mb21d2
uniprot id: A0A3B4DDV3
names: Similarity
messages: Belongs to the mab-21 family.

42514:igf2a
gene id: 42514:igf2a
uniprot id: A0A3B4E345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

42514:kctd13
gene id: 42514:kctd13
uniprot id: A0A3B4E638
names: Similarity
messages: Belongs to the BACURD family.

42514:gtf2h5
gene id: 42514:gtf2h5
uniprot id: A0A3B4C8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

42514:ndufc1
gene id: 42514:ndufc1
uniprot id: A0A3B4DF39
names: Similarity
names: Subunit
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.

42514:thada
gene id: 42514:thada
uniprot id: A0A3B4CAD7
uniprot id: A0A3B4DW55
names: Similarity
messages: Belongs to the THADA family.

42514:LOC108436202
gene id: 42514:LOC108436202
uniprot id: A0A3B4E4W9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:LOC108428702
gene id: 42514:LOC108428702
uniprot id: A0A3B4DJL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

42514:rngtt
gene id: 42514:rngtt
uniprot id: A0A3B4CAR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

42514:adrb2a
gene id: 42514:adrb2a
uniprot id: A0A3B4CRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:zgc:136908
gene id: 42514:zgc:136908
uniprot id: A0A3B4D5A1
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:acd
gene id: 42514:acd
uniprot id: A0A3B4BTM1
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

42514:gas8
gene id: 42514:gas8
uniprot id: A0A3B4DDQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

42514:tpmt.1
gene id: 42514:tpmt.1
uniprot id: A0A3B4EHI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

42514:LOC108439508
gene id: 42514:LOC108439508
uniprot id: A0A3B4CNT6
names: Similarity
messages: Belongs to the SH3RF family.

42514:tyw1
gene id: 42514:tyw1
uniprot id: A0A3B4DMY9
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

42514:zic2b
gene id: 42514:zic2b
uniprot id: A0A3B4C1S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

42514:LOC108430611
gene id: 42514:LOC108430611
uniprot id: A0A3B4BX07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:crybb3
gene id: 42514:crybb3
uniprot id: A0A3B4BPQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

42514:LOC108427413
gene id: 42514:LOC108427413
uniprot id: A0A3B4E2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

42514:chpt1
gene id: 42514:chpt1
uniprot id: A0A3B4E343
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

42514:LOC108444394
gene id: 42514:LOC108444394
uniprot id: A0A3B4DM63
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

42514:mphosph10
gene id: 42514:mphosph10
uniprot id: A0A3B4CUM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

42514:arl6
gene id: 42514:arl6
uniprot id: A0A3B4D2Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

42514:LOC108435092
gene id: 42514:LOC108435092
uniprot id: A0A3B4CWL0
uniprot id: A0A3B4CWM4
uniprot id: A0A3B4CX95
uniprot id: A0A3B4EB26
names: Similarity
messages: Belongs to the SEC2 family.

42514:isca2
gene id: 42514:isca2
uniprot id: A0A3B4CM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

42514:cdc42
gene id: 42514:cdc42
uniprot id: A0A3B4DQJ9
uniprot id: A0A3B4DS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

42514:ppp2r5a
gene id: 42514:ppp2r5a
uniprot id: A0A3B4C2I0
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

42514:ero1a
gene id: 42514:ero1a
uniprot id: A0A3B4C8I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

42514:nup58
gene id: 42514:nup58
uniprot id: A0A3B4CZH1
uniprot id: A0A3B4EBM6
names: Subcellular Location Annotation
messages: nuclear pore complex

42514:mvb12a
gene id: 42514:mvb12a
uniprot id: A0A3B4BN38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

42514:foxn3
gene id: 42514:foxn3
uniprot id: A0A3B4D905
names: Subcellular Location Annotation
messages: Nucleus

42514:lmln
gene id: 42514:lmln
uniprot id: A0A3B4C688
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

42514:atp8b4
gene id: 42514:atp8b4
uniprot id: A0A3B4CAP0
uniprot id: A0A3B4CCD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:hlx1
gene id: 42514:hlx1
uniprot id: A0A3B4BVY7
names: Subcellular Location Annotation
messages: Nucleus

42514:mtfr2
gene id: 42514:mtfr2
uniprot id: A0A3B4CLQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

42514:rps6
gene id: 42514:rps6
uniprot id: A0A3B4CLL7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

42514:LOC108438364
gene id: 42514:LOC108438364
uniprot id: A0A3B4D254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:arhgap32b
gene id: 42514:arhgap32b
uniprot id: A0A3B4E5Z3
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

42514:zc3h14
gene id: 42514:zc3h14
uniprot id: A0A3B4CT73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

42514:mcoln1a
gene id: 42514:mcoln1a
uniprot id: A0A3B4EEA1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

42514:ncln
gene id: 42514:ncln
uniprot id: A0A3B4BX35
names: Similarity
messages: Belongs to the nicastrin family.

42514:ihha
gene id: 42514:ihha
uniprot id: A0A3B4C6K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

42514:ltv1
gene id: 42514:ltv1
uniprot id: A0A3B4E361
names: Similarity
messages: Belongs to the LTV1 family.

42514:nxn
gene id: 42514:nxn
uniprot id: A0A3B4E846
names: Similarity
messages: Belongs to the nucleoredoxin family.

42514:raf1b
gene id: 42514:raf1b
uniprot id: A0A3B4DJH7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

42514:LOC108441124
gene id: 42514:LOC108441124
uniprot id: A0A3B4D2I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

42514:ipo13
gene id: 42514:ipo13
uniprot id: A0A3B4DJV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

42514:pcid2
gene id: 42514:pcid2
uniprot id: A0A3B4DSS9
names: Similarity
messages: Belongs to the CSN12 family.

42514:slc7a2
gene id: 42514:slc7a2
uniprot id: A0A3B4CQF0
uniprot id: A0A3B4CST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:rps28
gene id: 42514:rps28
uniprot id: A0A3B4EGG4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

42514:tead1b
gene id: 42514:tead1b
uniprot id: A0A3B4CER4
uniprot id: A0A3B4DX64
uniprot id: A0A3B4DZW3
uniprot id: A0A3B4E101
names: Subcellular Location Annotation
messages: Nucleus

42514:homezb
gene id: 42514:homezb
uniprot id: A0A3B4CXN4
names: Subcellular Location Annotation
messages: Nucleus

42514:srprb
gene id: 42514:srprb
uniprot id: A0A3B4DNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:pros1
gene id: 42514:pros1
uniprot id: A0A3B4DQG4
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:hcn4
gene id: 42514:hcn4
uniprot id: A0A3B4DGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

42514:gpc3
gene id: 42514:gpc3
uniprot id: A0A3B4CQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

42514:fcf1
gene id: 42514:fcf1
uniprot id: A0A3B4BVJ8
uniprot id: A0A3B4BYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

42514:hs6st1a
gene id: 42514:hs6st1a
uniprot id: A0A3B4EHH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

42514:itpr2
gene id: 42514:itpr2
uniprot id: A0A3B4E5B7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

42514:rxrba
gene id: 42514:rxrba
uniprot id: A0A3B4BZB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

42514:txlna
gene id: 42514:txlna
uniprot id: A0A3B4EPQ7
names: Similarity
messages: Belongs to the taxilin family.

42514:cdc14ab
gene id: 42514:cdc14ab
uniprot id: A0A3B4EAJ4
uniprot id: A0A3B4EET6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

42514:grpel2
gene id: 42514:grpel2
uniprot id: A0A3B4DXN3
names: Similarity
messages: Belongs to the GrpE family.

42514:ppp2cab
gene id: 42514:ppp2cab
uniprot id: A0A3B4E0S8
names: Similarity
messages: Belongs to the PPP phosphatase family.

42514:c3h16orf91
gene id: 42514:c3h16orf91
uniprot id: A0A3B4C4C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCSMST1 family.
messages: Membrane

42514:ptk7b
gene id: 42514:ptk7b
uniprot id: A0A3B4DV71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:stat5b
gene id: 42514:stat5b
uniprot id: A0A3B4C5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

42514:mrps7
gene id: 42514:mrps7
uniprot id: A0A3B4CLI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

42514:fbxo31
gene id: 42514:fbxo31
uniprot id: A0A3B4EMY0
uniprot id: A0A3B4EPT8
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

42514:gja4
gene id: 42514:gja4
uniprot id: A0A3B4BWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:LOC108440271
gene id: 42514:LOC108440271
uniprot id: A0A3B4C3W7
names: Similarity
messages: Belongs to the PACS family.

42514:nlgn4xa
gene id: 42514:nlgn4xa
uniprot id: A0A3B4CW20
uniprot id: A0A3B4CW31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

42514:fgd
gene id: 42514:fgd
uniprot id: A0A3B4E8B4
names: Subcellular Location Annotation
messages: cytoskeleton

42514:gbx2
gene id: 42514:gbx2
uniprot id: A0A3B4BSL3
names: Subcellular Location Annotation
messages: Nucleus

42514:vangl2
gene id: 42514:vangl2
uniprot id: A0A3B4CPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

42514:shbg
gene id: 42514:shbg
uniprot id: A0A3B4C1F9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:chico
gene id: 42514:chico
uniprot id: A0A3B4EFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:LOC108413310
gene id: 42514:LOC108413310
uniprot id: A0A3B4EMX8
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:ppcs
gene id: 42514:ppcs
uniprot id: A0A3B4DHE2
names: Similarity
messages: Belongs to the PPC synthetase family.

42514:fam174c
gene id: 42514:fam174c
uniprot id: A0A3B4EGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

42514:cep70
gene id: 42514:cep70
uniprot id: A0A3B4CWU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

42514:LOC108426368
gene id: 42514:LOC108426368
uniprot id: A0A3B4DKG2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:ireb2
gene id: 42514:ireb2
uniprot id: A0A3B4DBM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Cytoplasm
messages: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

42514:psmc5
gene id: 42514:psmc5
uniprot id: A0A3B4C103
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

42514:cdr2a
gene id: 42514:cdr2a
uniprot id: A0A3B4E6L8
names: Similarity
messages: Belongs to the CDR2 family.

42514:LOC108432285
gene id: 42514:LOC108432285
uniprot id: A0A3B4CSM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

42514:LOC108444404
gene id: 42514:LOC108444404
uniprot id: A0A3B4DIK9
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:LOC108434700
gene id: 42514:LOC108434700
uniprot id: A0A3B4E5M6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

42514:dhrs13a.2
gene id: 42514:dhrs13a.2
uniprot id: A0A3B4DAB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108414240
gene id: 42514:LOC108414240
uniprot id: A0A3B4DIH0
names: Similarity
messages: Belongs to the beta-catenin family.

42514:LOC108413555
gene id: 42514:LOC108413555
uniprot id: A0A3B4E0Q9
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

42514:si:ch211-106j24.1
gene id: 42514:si:ch211-106j24.1
uniprot id: A0A3B4CE00
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:LOC108431518
gene id: 42514:LOC108431518
uniprot id: A0A3B4BRZ2
names: Subcellular Location Annotation
messages: Membrane

42514:dnaaf4
gene id: 42514:dnaaf4
uniprot id: A0A3B4D256
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: neuron projection

42514:ptdss2
gene id: 42514:ptdss2
uniprot id: A0A3B4BVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:celf3a
gene id: 42514:celf3a
uniprot id: A0A3B4CL69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

42514:gpr156
gene id: 42514:gpr156
uniprot id: A0A3B4CVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:tpi1b
gene id: 42514:tpi1b
uniprot id: A0A3B4CT32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

42514:si:dkey-94e7.2
gene id: 42514:si:dkey-94e7.2
uniprot id: A0A3B4E8P5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:ntsr1
gene id: 42514:ntsr1
uniprot id: A0A3B4BSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:kin
gene id: 42514:kin
uniprot id: A0A3B4DKN5
names: Similarity
messages: Belongs to the KIN17 family.

42514:tubg1
gene id: 42514:tubg1
uniprot id: A0A3B4CH93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.
messages: centrosome

42514:sntb1
gene id: 42514:sntb1
uniprot id: A0A3B4DPM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

42514:LOC108437875
gene id: 42514:LOC108437875
uniprot id: A0A3B4CME8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

42514:nek7
gene id: 42514:nek7
uniprot id: A0A3B4C8K6
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:neu3.1
gene id: 42514:neu3.1
uniprot id: A0A3B4CKW8
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

42514:pdik1l
gene id: 42514:pdik1l
uniprot id: A0A3B4E8K6
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:tmem33
gene id: 42514:tmem33
uniprot id: A0A3B4D6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

42514:itga3b
gene id: 42514:itga3b
uniprot id: A0A3B4C7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:smarca5
gene id: 42514:smarca5
uniprot id: A0A3B4EJM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

42514:cuedc2
gene id: 42514:cuedc2
uniprot id: A0A3B4BS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

42514:anxa13l
gene id: 42514:anxa13l
uniprot id: A0A3B4E3N6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

42514:txnl4a
gene id: 42514:txnl4a
uniprot id: A0A3B4EFB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

42514:yaf2
gene id: 42514:yaf2
uniprot id: A0A3B4D027
names: Subcellular Location Annotation
messages: Nucleus

42514:timm13
gene id: 42514:timm13
uniprot id: A0A3B4BYT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

42514:LOC108430668
gene id: 42514:LOC108430668
uniprot id: A0A3B4CSX3
names: Similarity
messages: Belongs to the actin family.

42514:npepps
gene id: 42514:npepps
uniprot id: A0A3B4DVB3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:slc4a10b
gene id: 42514:slc4a10b
uniprot id: A0A3B4EF67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

42514:olfml3a
gene id: 42514:olfml3a
uniprot id: A0A3B4EBC2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:lypd6b
gene id: 42514:lypd6b
uniprot id: A0A3B4EN61
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:zgc:172271
gene id: 42514:zgc:172271
uniprot id: A0A3B4E3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted
messages: Transferrins are iron binding transport proteins which bind Fe(3+) ion in association with the binding of an anion, usually bicarbonate.

42514:kif19
gene id: 42514:kif19
uniprot id: A0A3B4DMC6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:tpte
gene id: 42514:tpte
uniprot id: A0A3B4D859
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

42514:acot13
gene id: 42514:acot13
uniprot id: A0A3B4DNS4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

42514:hacd1
gene id: 42514:hacd1
uniprot id: A0A3B4BPC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:sulf1
gene id: 42514:sulf1
uniprot id: A0A3B4CPX6
uniprot id: A0A3B4E7R2
uniprot id: A0A3B4E8Y1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:emg1
gene id: 42514:emg1
uniprot id: A0A3B4CU39
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

42514:abhd16a
gene id: 42514:abhd16a
uniprot id: A0A3B4CU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. ABHD16 family.
messages: Membrane

42514:tafa5b
gene id: 42514:tafa5b
uniprot id: A0A3B4CFH0
names: Similarity
messages: Belongs to the TAFA family.

42514:LOC108442778
gene id: 42514:LOC108442778
uniprot id: A0A3B4DEL8
names: Subcellular Location Annotation
messages: Cytoplasm

42514:lypla1
gene id: 42514:lypla1
uniprot id: A0A3B4ECF8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

42514:plcd4a
gene id: 42514:plcd4a
uniprot id: A0A3B4EEM4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus

42514:bnip1a
gene id: 42514:bnip1a
uniprot id: A0A3B4BYW0
names: Subcellular Location Annotation
messages: Membrane

42514:zgc:55461
gene id: 42514:zgc:55461
uniprot id: A0A3B4EFT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:mdm2
gene id: 42514:mdm2
uniprot id: A0A3B4BWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

42514:sh3bp5a
gene id: 42514:sh3bp5a
uniprot id: A0A3B4C0E9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

42514:ddx31
gene id: 42514:ddx31
uniprot id: A0A3B4ECI6
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:amd1
gene id: 42514:amd1
uniprot id: A0A3B4C2V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

42514:uox
gene id: 42514:uox
uniprot id: A0A3B4CID7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome

42514:cetn2
gene id: 42514:cetn2
uniprot id: A0A3B4E3C3
names: Similarity
messages: Belongs to the centrin family.

42514:gdpd1
gene id: 42514:gdpd1
uniprot id: A0A3B4DLZ1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

42514:urad
gene id: 42514:urad
uniprot id: A0A3B4EHN9
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

42514:llgl1
gene id: 42514:llgl1
uniprot id: A0A3B4EEA0
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

42514:b4galt2
gene id: 42514:b4galt2
uniprot id: A0A3B4BQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:pklr
gene id: 42514:pklr
uniprot id: A0A3B4CYK1
uniprot id: A0A3B4CYL1
names: Similarity
messages: Belongs to the pyruvate kinase family.

42514:smad4
gene id: 42514:smad4
uniprot id: A0A3B4CGU0
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108425945
gene id: 42514:LOC108425945
uniprot id: A0A3B4DFS9
names: Similarity
messages: Belongs to the dynein intermediate chain family.

42514:LOC108423542
gene id: 42514:LOC108423542
uniprot id: A0A3B4BQB2
uniprot id: A0A3B4DK70
names: Similarity
messages: Belongs to the sorting nexin family.

42514:LOC108440363
gene id: 42514:LOC108440363
uniprot id: A0A3B4BRW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:golt1ba
gene id: 42514:golt1ba
uniprot id: A0A3B4CHB8
uniprot id: A0A3B4E3W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

42514:LOC108431959
gene id: 42514:LOC108431959
uniprot id: A0A3B4DDI0
names: Similarity
messages: Belongs to the SELO family.

42514:hadhab
gene id: 42514:hadhab
uniprot id: A0A3B4E3D3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

42514:LOC108440432
gene id: 42514:LOC108440432
uniprot id: A0A3B4DBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: May be involved in sexual development.
messages: Nucleus

42514:slco4a1
gene id: 42514:slco4a1
uniprot id: A0A3B4DH23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:zgc:153441
gene id: 42514:zgc:153441
uniprot id: A0A3B4DCI2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:mrpl3
gene id: 42514:mrpl3
uniprot id: A0A3B4BPD6
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

42514:plaa
gene id: 42514:plaa
uniprot id: A0A3B4DSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

42514:LOC108415234
gene id: 42514:LOC108415234
uniprot id: A0A3B4CXD7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

42514:glud1b
gene id: 42514:glud1b
uniprot id: A0A3B4BY26
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

42514:LOC108430016
gene id: 42514:LOC108430016
uniprot id: A0A3B4D346
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:zgc:101810
gene id: 42514:zgc:101810
uniprot id: A0A3B4C477
names: Similarity
messages: Belongs to the actin family.

42514:LOC108410709
gene id: 42514:LOC108410709
uniprot id: A0A3B4CFN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:ctbs
gene id: 42514:ctbs
uniprot id: A0A3B4E2G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

42514:nme4
gene id: 42514:nme4
uniprot id: A0A3B4DK16
names: Similarity
messages: Belongs to the NDK family.

42514:esco1
gene id: 42514:esco1
uniprot id: A0A3B4EL15
names: Subcellular Location Annotation
messages: Nucleus

42514:zdhhc4
gene id: 42514:zdhhc4
uniprot id: A0A3B4C063
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:mpp3b
gene id: 42514:mpp3b
uniprot id: A0A3B4EG98
uniprot id: A0A3B4EGF7
names: Similarity
messages: Belongs to the MAGUK family.

42514:triqk
gene id: 42514:triqk
uniprot id: A0A3B4C462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:rrp12
gene id: 42514:rrp12
uniprot id: A0A3B4DI42
names: Similarity
messages: Belongs to the RRP12 family.

42514:ube2g1a
gene id: 42514:ube2g1a
uniprot id: A0A3B4DWH3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:tmem86a
gene id: 42514:tmem86a
uniprot id: A0A3B4DR58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

42514:cratb
gene id: 42514:cratb
uniprot id: A0A3B4DY99
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

42514:LOC108431906
gene id: 42514:LOC108431906
uniprot id: A0A3B4C677
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:gfm1
gene id: 42514:gfm1
uniprot id: A0A3B4BVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

42514:tubgcp4
gene id: 42514:tubgcp4
uniprot id: A0A3B4CXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

42514:atp5f1e
gene id: 42514:atp5f1e
uniprot id: A0A3B4DT11
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

42514:arhgef3l
gene id: 42514:arhgef3l
uniprot id: A0A3B4CL38
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

42514:gpbp1l1
gene id: 42514:gpbp1l1
uniprot id: A0A3B4BYU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

42514:st6gal2a
gene id: 42514:st6gal2a
uniprot id: A0A3B4BWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:LOC108440215
gene id: 42514:LOC108440215
uniprot id: A0A3B4C5Q6
names: Similarity
messages: Belongs to the globin family.

42514:cat
gene id: 42514:cat
uniprot id: A0A3B4DEY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

42514:LOC108433529
gene id: 42514:LOC108433529
uniprot id: A0A3B4CJI1
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.
messages: Belongs to the MoaD family. MOCS2A subfamily.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2B).
messages: cytosol

42514:LOC108434482
gene id: 42514:LOC108434482
uniprot id: A0A3B4EH64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

42514:msi2a
gene id: 42514:msi2a
uniprot id: A0A3B4CEX2
uniprot id: A0A3B4E1C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

42514:LOC108411427
gene id: 42514:LOC108411427
uniprot id: A0A3B4BPG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

42514:irx4b
gene id: 42514:irx4b
uniprot id: A0A3B4ENT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

42514:tmem65
gene id: 42514:tmem65
uniprot id: A0A3B4DQ55
uniprot id: A0A3B4DRJ7
names: Subcellular Location Annotation
messages: Membrane

42514:tgfb5
gene id: 42514:tgfb5
uniprot id: A0A3B4ELT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

42514:ttc36
gene id: 42514:ttc36
uniprot id: A0A3B4DMN7
names: Similarity
messages: Belongs to the TTC36 family.

42514:ccdc47
gene id: 42514:ccdc47
uniprot id: A0A3B4CIG1
names: Subcellular Location Annotation
messages: Membrane
messages: Rough endoplasmic reticulum membrane

42514:pcsk6
gene id: 42514:pcsk6
uniprot id: A0A3B4DWS8
names: Similarity
messages: Belongs to the peptidase S8 family.

42514:nim1k
gene id: 42514:nim1k
uniprot id: A0A3B4EHC5
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:fam49a
gene id: 42514:fam49a
uniprot id: A0A3B4DIT3
uniprot id: A0A3B4DMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

42514:prim1
gene id: 42514:prim1
uniprot id: A0A3B4CF51
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

42514:csad
gene id: 42514:csad
uniprot id: A0A3B4ED67
names: Similarity
messages: Belongs to the group II decarboxylase family.

42514:LOC108419124
gene id: 42514:LOC108419124
uniprot id: A0A3B4CU81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:picalma
gene id: 42514:picalma
uniprot id: A0A3B4CNP2
uniprot id: A0A3B4CQZ7
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

42514:hoxd12a
gene id: 42514:hoxd12a
uniprot id: A0A3B4EB81
names: Subcellular Location Annotation
messages: Nucleus

42514:pitrm1
gene id: 42514:pitrm1
uniprot id: A0A3B4CS72
names: Subunit
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

42514:tbx5b
gene id: 42514:tbx5b
uniprot id: A0A3B4BSX8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:psen2
gene id: 42514:psen2
uniprot id: A0A3B4CCI6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

42514:mrpl40
gene id: 42514:mrpl40
uniprot id: A0A3B4BLU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

42514:LOC108415324
gene id: 42514:LOC108415324
uniprot id: A0A3B4CRC3
names: Similarity
messages: Belongs to the MHC class I family.

42514:kif7
gene id: 42514:kif7
uniprot id: A0A3B4C756
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:sgcd
gene id: 42514:sgcd
uniprot id: A0A3B4CLS5
uniprot id: A0A3B4CLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

42514:napbb
gene id: 42514:napbb
uniprot id: A0A3B4E4T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

42514:odad4
gene id: 42514:odad4
uniprot id: A0A3B4DE83
names: Subcellular Location Annotation
messages: cilium axoneme

42514:tmem186
gene id: 42514:tmem186
uniprot id: A0A3B4CJQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

42514:foxd3
gene id: 42514:foxd3
uniprot id: A0A3B4BXE1
names: Subcellular Location Annotation
messages: Nucleus

42514:opn7d
gene id: 42514:opn7d
uniprot id: A0A3B4E3X8
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108425948
gene id: 42514:LOC108425948
uniprot id: A0A3B4DFS3
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:tmpob
gene id: 42514:tmpob
uniprot id: A0A3B4DHG1
names: Similarity
messages: Belongs to the LEM family.

42514:wu:fa11c10
gene id: 42514:wu:fa11c10
uniprot id: A0A3B4C6A2
names: Similarity
messages: Belongs to the FAM110 family.

42514:hs6st3a
gene id: 42514:hs6st3a
uniprot id: A0A3B4DQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

42514:LOC108431611
gene id: 42514:LOC108431611
uniprot id: A0A3B4EQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:si:ch211-168k14.2
gene id: 42514:si:ch211-168k14.2
uniprot id: A0A3B4C6G4
names: Similarity
messages: Belongs to the phospholipase D family.

42514:paqr5b
gene id: 42514:paqr5b
uniprot id: A0A3B4CBJ8
uniprot id: A0A3B4CCQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:sec22bb
gene id: 42514:sec22bb
uniprot id: A0A3B4D4D2
uniprot id: A0A3B4EEX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

42514:suds3
gene id: 42514:suds3
uniprot id: A0A3B4DQI9
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108415880
gene id: 42514:LOC108415880
uniprot id: A0A3B4D3G8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:serinc2l
gene id: 42514:serinc2l
uniprot id: A0A3B4CVZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

42514:ddi2
gene id: 42514:ddi2
uniprot id: A0A3B4CIP9
names: Similarity
messages: Belongs to the DDI1 family.

42514:LOC108440707
gene id: 42514:LOC108440707
uniprot id: A0A3B4CHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:ube2a
gene id: 42514:ube2a
uniprot id: A0A3B4CP09
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:LOC108436226
gene id: 42514:LOC108436226
uniprot id: A0A3B4E5R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Cytoplasm
messages: Nucleus

42514:f7
gene id: 42514:f7
uniprot id: A0A3B4BZD1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:pi4k2a
gene id: 42514:pi4k2a
uniprot id: A0A3B4DSX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

42514:idi1
gene id: 42514:idi1
uniprot id: A0A3B4DDZ2
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

42514:LOC108412896
gene id: 42514:LOC108412896
uniprot id: A0A3B4E4A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

42514:cdh12a
gene id: 42514:cdh12a
uniprot id: A0A3B4CWZ1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:LOC108434745
gene id: 42514:LOC108434745
uniprot id: A0A3B4E201
names: Subcellular Location Annotation
messages: Nucleus

42514:rps2
gene id: 42514:rps2
uniprot id: A0A3B4EKH1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

42514:eno2
gene id: 42514:eno2
uniprot id: A0A3B4DKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

42514:LOC108412219
gene id: 42514:LOC108412219
uniprot id: A0A3B4CN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

42514:napab
gene id: 42514:napab
uniprot id: A0A3B4D689
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

42514:LOC108434377
gene id: 42514:LOC108434377
uniprot id: A0A3B4DGX7
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108430333
gene id: 42514:LOC108430333
uniprot id: A0A3B4BRX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

42514:slc26a5
gene id: 42514:slc26a5
uniprot id: A0A3B4CHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

42514:casc3
gene id: 42514:casc3
uniprot id: A0A3B4CHT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

42514:pus1
gene id: 42514:pus1
uniprot id: A0A3B4EK11
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

42514:LOC108432118
gene id: 42514:LOC108432118
uniprot id: A0A3B4DHA6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:LOC108427489
gene id: 42514:LOC108427489
uniprot id: A0A3B4DQY6
names: Similarity
messages: Belongs to the ZC3H12 family.

42514:LOC108434239
gene id: 42514:LOC108434239
uniprot id: A0A3B4BY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C65 family. Otulin subfamily.
messages: Cytoplasm

42514:cd79a
gene id: 42514:cd79a
uniprot id: A0A3B4D8S4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:glra1
gene id: 42514:glra1
uniprot id: A0A3B4D4Q8
uniprot id: A0A3B4EEB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

42514:laptm4a
gene id: 42514:laptm4a
uniprot id: A0A3B4DTR3
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

42514:tead3b
gene id: 42514:tead3b
uniprot id: A0A3B4DKF4
uniprot id: A0A3B4DKH0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

42514:proza
gene id: 42514:proza
uniprot id: A0A3B4CY37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:celsr1b
gene id: 42514:celsr1b
uniprot id: A0A3B4CTJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

42514:wnt9b
gene id: 42514:wnt9b
uniprot id: A0A3B4CJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:mtus1a
gene id: 42514:mtus1a
uniprot id: A0A3B4CNS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTUS1 family.
messages: Nucleus

42514:trim9
gene id: 42514:trim9
uniprot id: A0A3B4CB70
uniprot id: A0A3B4DWK4
names: Subcellular Location Annotation
messages: cytoskeleton

42514:ywhabl
gene id: 42514:ywhabl
uniprot id: A0A3B4EK91
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:mcm8
gene id: 42514:mcm8
uniprot id: A0A3B4BP21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

42514:slc16a4
gene id: 42514:slc16a4
uniprot id: A0A3B4BKS6
names: Subcellular Location Annotation
messages: Membrane

42514:cpe
gene id: 42514:cpe
uniprot id: A0A3B4C292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

42514:ptprma
gene id: 42514:ptprma
uniprot id: A0A3B4EKV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

42514:LOC108444182
gene id: 42514:LOC108444182
uniprot id: A0A3B4CNK9
names: Similarity
messages: Belongs to the ANKLE2 family.

42514:rnf34a
gene id: 42514:rnf34a
uniprot id: A0A3B4CVW1
uniprot id: A0A3B4CVW8
uniprot id: A0A3B4EBN1
names: Subcellular Location Annotation
messages: Cell membrane

42514:crybb2
gene id: 42514:crybb2
uniprot id: A0A3B4DMH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

42514:papss1
gene id: 42514:papss1
uniprot id: A0A3B4D0X4
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

42514:gpr4
gene id: 42514:gpr4
uniprot id: A0A3B4BWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:foxo1b
gene id: 42514:foxo1b
uniprot id: A0A3B4BPZ6
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108440942
gene id: 42514:LOC108440942
uniprot id: A0A3B4BU16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

42514:tmem170a
gene id: 42514:tmem170a
uniprot id: A0A3B4CJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

42514:si:ch211-107n13.1
gene id: 42514:si:ch211-107n13.1
uniprot id: A0A3B4BXR4
names: Similarity
messages: Belongs to the FAM110 family.

42514:LOC108443671
gene id: 42514:LOC108443671
uniprot id: A0A3B4DMM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tmem11
gene id: 42514:tmem11
uniprot id: A0A3B4C757
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in mitochondrial morphogenesis.

42514:LOC108425188
gene id: 42514:LOC108425188
uniprot id: A0A3B4CE86
uniprot id: A0A3B4E1R2
uniprot id: A0A3B4E1S2
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

42514:ing2
gene id: 42514:ing2
uniprot id: A0A3B4EBP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

42514:prpf38a
gene id: 42514:prpf38a
uniprot id: A0A3B4DQY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

42514:LOC108437088
gene id: 42514:LOC108437088
uniprot id: A0A3B4C096
names: Similarity
messages: Belongs to the TGF-beta family.

42514:slc37a4b
gene id: 42514:slc37a4b
uniprot id: A0A3B4DCK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

42514:zgc:153675
gene id: 42514:zgc:153675
uniprot id: A0A3B4C8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

42514:ppl
gene id: 42514:ppl
uniprot id: A0A3B4DWV7
names: Subcellular Location Annotation
messages: cytoskeleton

42514:snx10a
gene id: 42514:snx10a
uniprot id: A0A3B4BRF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

42514:ninj2
gene id: 42514:ninj2
uniprot id: A0A3B4DNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

42514:calb2a
gene id: 42514:calb2a
uniprot id: A0A3B4C3I0
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

42514:fam8a1b
gene id: 42514:fam8a1b
uniprot id: A0A3B4EJV3
names: Subcellular Location Annotation
messages: Membrane

42514:ntrk3b
gene id: 42514:ntrk3b
uniprot id: A0A3B4C7B3
uniprot id: A0A3B4C970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:si:ch211-119c20.2
gene id: 42514:si:ch211-119c20.2
uniprot id: A0A3B4BWT6
uniprot id: A0A3B4C0B4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:zgc:91976
gene id: 42514:zgc:91976
uniprot id: A0A3B4C9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

42514:tubb4b
gene id: 42514:tubb4b
uniprot id: A0A3B4DBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:nup35
gene id: 42514:nup35
uniprot id: A0A3B4CBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

42514:LOC108430427
gene id: 42514:LOC108430427
uniprot id: A0A3B4BP02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

42514:khdrbs3
gene id: 42514:khdrbs3
uniprot id: A0A3B4DY18
names: Similarity
messages: Belongs to the KHDRBS family.

42514:elavl1a
gene id: 42514:elavl1a
uniprot id: A0A3B4DRH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

42514:slc20a1b
gene id: 42514:slc20a1b
uniprot id: A0A3B4BY99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

42514:jpt1b
gene id: 42514:jpt1b
uniprot id: A0A3B4CHF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

42514:inhbaa
gene id: 42514:inhbaa
uniprot id: A0A3B4DJQ7
names: Similarity
messages: Belongs to the TGF-beta family.

42514:cplx4c
gene id: 42514:cplx4c
uniprot id: A0A3B4D634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

42514:LOC108411062
gene id: 42514:LOC108411062
uniprot id: A0A3B4ECG0
names: Similarity
messages: Belongs to the SLITRK family.

42514:LOC108418701
gene id: 42514:LOC108418701
uniprot id: A0A3B4CY83
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:cacng7b
gene id: 42514:cacng7b
uniprot id: A0A3B4E5Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

42514:pfdn1
gene id: 42514:pfdn1
uniprot id: A0A3B4C825
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

42514:kcnc1a
gene id: 42514:kcnc1a
uniprot id: A0A3B4CGA6
names: Subcellular Location Annotation
messages: Membrane

42514:evpla
gene id: 42514:evpla
uniprot id: A0A3B4DEK5
names: Subcellular Location Annotation
messages: cytoskeleton

42514:snx18b
gene id: 42514:snx18b
uniprot id: A0A3B4CJB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

42514:LOC108411208
gene id: 42514:LOC108411208
uniprot id: A0A3B4C7I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

42514:sema3bl
gene id: 42514:sema3bl
uniprot id: A0A3B4CQU3
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tgm1l1
gene id: 42514:tgm1l1
uniprot id: A0A3B4ENX7
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

42514:snrnp27
gene id: 42514:snrnp27
uniprot id: A0A3B4BNQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNUT3 family.
messages: May play a role in mRNA splicing.
messages: Nucleus
messages: Part of a tri-snRNP complex.

42514:ifitm5
gene id: 42514:ifitm5
uniprot id: A0A3B4BVE4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

42514:uba3
gene id: 42514:uba3
uniprot id: A0A3B4CGH6
uniprot id: A0A3B4E1K8
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

42514:dmbx1b
gene id: 42514:dmbx1b
uniprot id: A0A3B4C5U5
names: Subcellular Location Annotation
messages: Nucleus

42514:ccnyl1
gene id: 42514:ccnyl1
uniprot id: A0A3B4D724
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

42514:clptm1
gene id: 42514:clptm1
uniprot id: A0A3B4BWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

42514:nifk
gene id: 42514:nifk
uniprot id: A0A3B4CLD2
names: Subcellular Location Annotation
messages: nucleolus

42514:ntf3
gene id: 42514:ntf3
uniprot id: A0A3B4DFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

42514:rps8a
gene id: 42514:rps8a
uniprot id: A0A3B4DS56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

42514:atp6v1ba
gene id: 42514:atp6v1ba
uniprot id: A0A3B4D5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

42514:oprd1a
gene id: 42514:oprd1a
uniprot id: A0A3B4DSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:palm3
gene id: 42514:palm3
uniprot id: A0A3B4D884
names: Similarity
messages: Belongs to the paralemmin family.

42514:gfm2
gene id: 42514:gfm2
uniprot id: A0A3B4E623
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

42514:LOC108425447
gene id: 42514:LOC108425447
uniprot id: A0A3B4EI82
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

42514:antxr2a
gene id: 42514:antxr2a
uniprot id: A0A3B4CQ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

42514:grin2ca
gene id: 42514:grin2ca
uniprot id: A0A3B4D4W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

42514:hnf4a
gene id: 42514:hnf4a
uniprot id: A0A3B4CSG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:fgg
gene id: 42514:fgg
uniprot id: A0A3B4BQ91
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

42514:LOC108438993
gene id: 42514:LOC108438993
uniprot id: A0A3B4CMS7
names: Subcellular Location Annotation
messages: Membrane

42514:cd82b
gene id: 42514:cd82b
uniprot id: A0A3B4EFU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:stard5
gene id: 42514:stard5
uniprot id: A0A3B4DUU7
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

42514:ppip5k2
gene id: 42514:ppip5k2
uniprot id: A0A3B4EB57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

42514:zgc:153311
gene id: 42514:zgc:153311
uniprot id: A0A3B4D7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:ppifa
gene id: 42514:ppifa
uniprot id: A0A3B4DFY0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:LOC108414108
gene id: 42514:LOC108414108
uniprot id: A0A3B4EK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:LOC108412875
gene id: 42514:LOC108412875
uniprot id: A0A3B4CGU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

42514:afg1la
gene id: 42514:afg1la
uniprot id: A0A3B4BM81
names: Similarity
messages: Belongs to the AFG1 ATPase family.

42514:hmga2
gene id: 42514:hmga2
uniprot id: A0A3B4DN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

42514:lipf
gene id: 42514:lipf
uniprot id: A0A3B4DN44
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

42514:sst6
gene id: 42514:sst6
uniprot id: A0A3B4EEJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

42514:gba3
gene id: 42514:gba3
uniprot id: A0A3B4BZN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

42514:vipr1b
gene id: 42514:vipr1b
uniprot id: A0A3B4CSN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

42514:raf1a
gene id: 42514:raf1a
uniprot id: A0A3B4CVQ7
uniprot id: A0A3B4CZE9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

42514:tmem35
gene id: 42514:tmem35
uniprot id: A0A3B4CNJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

42514:sh3bgrl3
gene id: 42514:sh3bgrl3
uniprot id: A0A3B4EHF1
names: Similarity
messages: Belongs to the SH3BGR family.

42514:hspb3
gene id: 42514:hspb3
uniprot id: A0A3B4CU67
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:reep2
gene id: 42514:reep2
uniprot id: A0A3B4D5Z4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:ptpn12
gene id: 42514:ptpn12
uniprot id: A0A3B4BTF8
uniprot id: A0A3B4DJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
messages: Cytoplasm
messages: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.

42514:ttc39c
gene id: 42514:ttc39c
uniprot id: A0A3B4CWR1
names: Similarity
messages: Belongs to the TTC39 family.

42514:snx9a
gene id: 42514:snx9a
uniprot id: A0A3B4D7A0
uniprot id: A0A3B4EJV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

42514:sat1b
gene id: 42514:sat1b
uniprot id: A0A3B4D8D2
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

42514:LOC108443808
gene id: 42514:LOC108443808
uniprot id: A0A3B4DHH5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

42514:epn3a
gene id: 42514:epn3a
uniprot id: A0A3B4CCB9
uniprot id: A0A3B4CE56
names: Similarity
messages: Belongs to the epsin family.

42514:mto1
gene id: 42514:mto1
uniprot id: A0A3B4ECX9
names: Function
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

42514:hoxa5a
gene id: 42514:hoxa5a
uniprot id: A0A3B4BMV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:LOC108442518
gene id: 42514:LOC108442518
uniprot id: A0A3B4C442
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

42514:uck2b
gene id: 42514:uck2b
uniprot id: A0A3B4CP50
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

42514:chata
gene id: 42514:chata
uniprot id: A0A3B4BSL9
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

42514:LOC108436205
gene id: 42514:LOC108436205
uniprot id: A0A3B4E576
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

42514:acp7
gene id: 42514:acp7
uniprot id: A0A3B4CUR1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

42514:pafah1b1b
gene id: 42514:pafah1b1b
uniprot id: A0A3B4DXC1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Component of the cytosolic PAF-AH (I) heterotetrameric enzyme, which is composed of PAFAH1B1 (beta), PAFAH1B2 (alpha2) and PAFAH1B3 (alpha1) subunits. The catalytic activity of the enzyme resides in the alpha1 (PAFAH1B3) and alpha2 (PAFAH1B2) subunits, whereas the beta subunit (PAFAH1B1) has regulatory activity. Trimer formation is not essential for the catalytic activity (By similarity). Interacts with dynein, dynactin, nde1 and ndel1.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

42514:si:ch211-157c3.4
gene id: 42514:si:ch211-157c3.4
uniprot id: A0A3B4EGS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

42514:emc10
gene id: 42514:emc10
uniprot id: A0A3B4DSY2
uniprot id: A0A3B4DSY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC10 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

42514:mcm3
gene id: 42514:mcm3
uniprot id: A0A3B4ENS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

42514:piwil1
gene id: 42514:piwil1
uniprot id: A0A3B4C7Y7
names: Similarity
messages: Belongs to the argonaute family.

42514:LOC108414495
gene id: 42514:LOC108414495
uniprot id: A0A3B4D5V2
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108425558
gene id: 42514:LOC108425558
uniprot id: A0A3B4CSW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

42514:LOC108431810
gene id: 42514:LOC108431810
uniprot id: A0A3B4CN01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

42514:LOC108443125
gene id: 42514:LOC108443125
uniprot id: A0A3B4EEK1
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

42514:LOC108438614
gene id: 42514:LOC108438614
uniprot id: A0A3B4CCV3
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

42514:LOC108429324
gene id: 42514:LOC108429324
uniprot id: A0A3B4DD83
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108444070
gene id: 42514:LOC108444070
uniprot id: A0A3B4CZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

42514:idh3g
gene id: 42514:idh3g
uniprot id: A0A3B4EB11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

42514:hpcal4
gene id: 42514:hpcal4
uniprot id: A0A3B4DNM5
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

42514:copz2
gene id: 42514:copz2
uniprot id: A0A3B4CE58
uniprot id: A0A3B4CG08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

42514:birc2
gene id: 42514:birc2
uniprot id: A0A3B4CBP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

42514:dpm3
gene id: 42514:dpm3
uniprot id: A0A3B4CMT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.

42514:LOC108423941
gene id: 42514:LOC108423941
uniprot id: A0A3B4CAP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

42514:ppp1r3b
gene id: 42514:ppp1r3b
uniprot id: A0A3B4DPM3
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

42514:LOC108424737
gene id: 42514:LOC108424737
uniprot id: A0A3B4BPA0
uniprot id: A0A3B4DHC2
names: Similarity
messages: Belongs to the TOM1 family.

42514:tyr
gene id: 42514:tyr
uniprot id: A0A3B4D9D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

42514:mmachc
gene id: 42514:mmachc
uniprot id: A0A3B4BP35
names: Similarity
messages: Belongs to the MMACHC family.

42514:bmpr1aa
gene id: 42514:bmpr1aa
uniprot id: A0A3B4DJJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:csf3a
gene id: 42514:csf3a
uniprot id: A0A3B4BP92
names: Similarity
messages: Belongs to the IL-6 superfamily.

42514:aadac
gene id: 42514:aadac
uniprot id: A0A3B4DL79
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

42514:foxk1
gene id: 42514:foxk1
uniprot id: A0A3B4CXQ9
names: Subcellular Location Annotation
messages: Nucleus

42514:sema3h
gene id: 42514:sema3h
uniprot id: A0A3B4CPR5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:unk
gene id: 42514:unk
uniprot id: A0A3B4C1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

42514:gpt2l
gene id: 42514:gpt2l
uniprot id: A0A3B4DRF2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

42514:postnb
gene id: 42514:postnb
uniprot id: A0A3B4BPT4
names: Subcellular Location Annotation
messages: extracellular matrix

42514:faslg
gene id: 42514:faslg
uniprot id: A0A3B4BNA7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:LOC108442067
gene id: 42514:LOC108442067
uniprot id: A0A3B4BQY9
uniprot id: A0A3B4BR19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

42514:dcps
gene id: 42514:dcps
uniprot id: A0A3B4BQR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

42514:trnt1
gene id: 42514:trnt1
uniprot id: A0A3B4DKG5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

42514:LOC108429917
gene id: 42514:LOC108429917
uniprot id: A0A3B4D5D8
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

42514:osbpl8
gene id: 42514:osbpl8
uniprot id: A0A3B4DQX2
names: Similarity
messages: Belongs to the OSBP family.

42514:LOC108444564
gene id: 42514:LOC108444564
uniprot id: A0A3B4EIF2
names: Similarity
messages: Belongs to the cornifelin family.

42514:snphb
gene id: 42514:snphb
uniprot id: A0A3B4E0Y0
names: Subcellular Location Annotation
messages: Membrane

42514:hbba1
gene id: 42514:hbba1
uniprot id: A0A3B4C712
names: Similarity
messages: Belongs to the globin family.

42514:lsm3
gene id: 42514:lsm3
uniprot id: A0A3B4CYR5
uniprot id: A0A3B4D124
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

42514:kcnk3b
gene id: 42514:kcnk3b
uniprot id: A0A3B4CIY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:tp53i11b
gene id: 42514:tp53i11b
uniprot id: A0A3B4C1I5
names: Subcellular Location Annotation
messages: Membrane

42514:atp1a3b
gene id: 42514:atp1a3b
uniprot id: A0A3B4CVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

42514:fzd8a
gene id: 42514:fzd8a
uniprot id: A0A3B4EPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

42514:eif2s1b
gene id: 42514:eif2s1b
uniprot id: A0A3B4C285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

42514:LOC108428227
gene id: 42514:LOC108428227
uniprot id: A0A3B4D1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

42514:cog6
gene id: 42514:cog6
uniprot id: A0A3B4BZK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.

42514:idua
gene id: 42514:idua
uniprot id: A0A3B4DT80
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

42514:ube2d2
gene id: 42514:ube2d2
uniprot id: A0A3B4BNP4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:odf2a
gene id: 42514:odf2a
uniprot id: A0A3B4BVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

42514:leprotl1
gene id: 42514:leprotl1
uniprot id: A0A3B4DX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

42514:pik3r3b
gene id: 42514:pik3r3b
uniprot id: A0A3B4DQK3
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

42514:orc1
gene id: 42514:orc1
uniprot id: A0A3B4BZY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

42514:efna2a
gene id: 42514:efna2a
uniprot id: A0A3B4C419
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:slc34a2b
gene id: 42514:slc34a2b
uniprot id: A0A3B4D9F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport.
messages: Membrane

42514:fam174b
gene id: 42514:fam174b
uniprot id: A0A3B4CJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

42514:tmem230b
gene id: 42514:tmem230b
uniprot id: A0A3B4BN84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

42514:mfge8b
gene id: 42514:mfge8b
uniprot id: A0A3B4CZS5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108413244
gene id: 42514:LOC108413244
uniprot id: A0A3B4BRZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

42514:LOC108427450
gene id: 42514:LOC108427450
uniprot id: A0A3B4DXL5
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

42514:ankrd13d
gene id: 42514:ankrd13d
uniprot id: A0A3B4D6V9
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

42514:lbh
gene id: 42514:lbh
uniprot id: A0A3B4DS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus

42514:ddx3xb
gene id: 42514:ddx3xb
uniprot id: A0A3B4DQC6
uniprot id: A0A3B4DRD8
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:LOC108424458
gene id: 42514:LOC108424458
uniprot id: A0A3B4E1N3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

42514:ednrab
gene id: 42514:ednrab
uniprot id: A0A3B4EH45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

42514:LOC108427579
gene id: 42514:LOC108427579
uniprot id: A0A3B4BW54
names: Subcellular Location Annotation
messages: Membrane

42514:rpl6
gene id: 42514:rpl6
uniprot id: A0A3B4BLT2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

42514:LOC108418154
gene id: 42514:LOC108418154
uniprot id: A0A3B4EEB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

42514:cct8
gene id: 42514:cct8
uniprot id: A0A3B4CJT5
uniprot id: A0A3B4E1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

42514:brd1a
gene id: 42514:brd1a
uniprot id: A0A3B4DJX3
names: Subcellular Location Annotation
messages: Nucleus

42514:mmp16b
gene id: 42514:mmp16b
uniprot id: A0A3B4DU56
names: Similarity
messages: Belongs to the peptidase M10A family.

42514:mmp19
gene id: 42514:mmp19
uniprot id: A0A3B4BT67
names: Similarity
messages: Belongs to the peptidase M10A family.

42514:ccdc126
gene id: 42514:ccdc126
uniprot id: A0A3B4BMB7
names: Subcellular Location Annotation
messages: Secreted

42514:LOC108415799
gene id: 42514:LOC108415799
uniprot id: A0A3B4EEP5
names: Similarity
messages: Belongs to the asteroid family.

42514:rfc4
gene id: 42514:rfc4
uniprot id: A0A3B4DW66
names: Similarity
messages: Belongs to the activator 1 small subunits family.

42514:tspan5b
gene id: 42514:tspan5b
uniprot id: A0A3B4CD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:si:ch211-149b19.3
gene id: 42514:si:ch211-149b19.3
uniprot id: A0A3B4BQL4
names: Similarity
messages: Belongs to the PP2C family.

42514:parp9
gene id: 42514:parp9
uniprot id: A0A3B4ENW4
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:s1pr3a
gene id: 42514:s1pr3a
uniprot id: A0A3B4DPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:gja8b
gene id: 42514:gja8b
uniprot id: A0A3B4DK64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:atg4a
gene id: 42514:atg4a
uniprot id: A0A3B4D8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

42514:zgc:113333
gene id: 42514:zgc:113333
uniprot id: A0A3B4D828
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

42514:vps25
gene id: 42514:vps25
uniprot id: A0A3B4D5Z3
names: Similarity
messages: Belongs to the VPS25 family.

42514:tfcp2
gene id: 42514:tfcp2
uniprot id: A0A3B4EDS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

42514:mipb
gene id: 42514:mipb
uniprot id: A0A3B4DPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:fgfr2
gene id: 42514:fgfr2
uniprot id: A0A3B4BQX7
uniprot id: A0A3B4BQY2
uniprot id: A0A3B4BUF8
uniprot id: A0A3B4DKT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:stxbp1a
gene id: 42514:stxbp1a
uniprot id: A0A3B4DC95
uniprot id: A0A3B4DGL4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

42514:galr2b
gene id: 42514:galr2b
uniprot id: A0A3B4BY47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:grik1a
gene id: 42514:grik1a
uniprot id: A0A3B4CJC1
uniprot id: A0A3B4CKU7
uniprot id: A0A3B4E175
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:cemip2
gene id: 42514:cemip2
uniprot id: A0A3B4D3H4
names: Similarity
messages: Belongs to the CEMIP family.

42514:tmed1a
gene id: 42514:tmed1a
uniprot id: A0A3B4E8H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

42514:si:ch211-247n2.1
gene id: 42514:si:ch211-247n2.1
uniprot id: A0A3B4CFT9
uniprot id: A0A3B4CFU4
uniprot id: A0A3B4CH80
uniprot id: A0A3B4E2U0
names: Subcellular Location Annotation
messages: Membrane

42514:ric3a
gene id: 42514:ric3a
uniprot id: A0A3B4CJ87
names: Similarity
messages: Belongs to the ric-3 family.

42514:nle1
gene id: 42514:nle1
uniprot id: A0A3B4BWU1
names: Subcellular Location Annotation
messages: nucleolus

42514:plat
gene id: 42514:plat
uniprot id: A0A3B4DHQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:recql
gene id: 42514:recql
uniprot id: A0A3B4EQF1
uniprot id: A0A3B4EQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

42514:brinp3a.1
gene id: 42514:brinp3a.1
uniprot id: A0A3B4C2B8
names: Similarity
messages: Belongs to the BRINP family.

42514:sdr16c5a
gene id: 42514:sdr16c5a
uniprot id: A0A3B4EPP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:gpsm1b
gene id: 42514:gpsm1b
uniprot id: A0A3B4BLH0
uniprot id: A0A3B4BPL0
names: Similarity
messages: Belongs to the GPSM family.

42514:lpcat3
gene id: 42514:lpcat3
uniprot id: A0A3B4CQV8
names: Subcellular Location Annotation
messages: Membrane

42514:mpc2b
gene id: 42514:mpc2b
uniprot id: A0A3B4D1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

42514:stambpb
gene id: 42514:stambpb
uniprot id: A0A3B4EER2
names: Similarity
messages: Belongs to the peptidase M67C family.

42514:sirt4
gene id: 42514:sirt4
uniprot id: A0A3B4CGX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

42514:hdac7a
gene id: 42514:hdac7a
uniprot id: A0A3B4DRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

42514:fitm2
gene id: 42514:fitm2
uniprot id: A0A3B4E809
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108443114
gene id: 42514:LOC108443114
uniprot id: A0A3B4BXR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

42514:LOC108439842
gene id: 42514:LOC108439842
uniprot id: A0A3B4D4Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:aldh4a1
gene id: 42514:aldh4a1
uniprot id: A0A3B4ENF6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:atp8b3
gene id: 42514:atp8b3
uniprot id: A0A3B4EPW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:hpse2
gene id: 42514:hpse2
uniprot id: A0A3B4ERS3
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

42514:crtc3
gene id: 42514:crtc3
uniprot id: A0A3B4EDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

42514:dlat
gene id: 42514:dlat
uniprot id: A0A3B4CDL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

42514:LOC108427823
gene id: 42514:LOC108427823
uniprot id: A0A3B4CXA9
names: Similarity
messages: Belongs to the NKAP family.

42514:jag1a
gene id: 42514:jag1a
uniprot id: A0A3B4CAU1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

42514:snx19b
gene id: 42514:snx19b
uniprot id: A0A3B4EJI2
names: Similarity
messages: Belongs to the sorting nexin family.

42514:toe1
gene id: 42514:toe1
uniprot id: A0A3B4CUR2
uniprot id: A0A3B4CWV8
names: Similarity
messages: Belongs to the CAF1 family.

42514:LOC108424633
gene id: 42514:LOC108424633
uniprot id: A0A3B4BPN2
uniprot id: A0A3B4DIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

42514:vamp5
gene id: 42514:vamp5
uniprot id: A0A3B4D0E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

42514:sez6l2
gene id: 42514:sez6l2
uniprot id: A0A3B4CKU2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:polr1a
gene id: 42514:polr1a
uniprot id: A0A3B4CMN2
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

42514:slc39a5
gene id: 42514:slc39a5
uniprot id: A0A3B4EJM1
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108425092
gene id: 42514:LOC108425092
uniprot id: A0A3B4CLG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

42514:LOC108442591
gene id: 42514:LOC108442591
uniprot id: A0A3B4BQX9
uniprot id: A0A3B4BU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:kcns3a
gene id: 42514:kcns3a
uniprot id: A0A3B4BYI0
names: Subcellular Location Annotation
messages: Membrane

42514:scarb2a
gene id: 42514:scarb2a
uniprot id: A0A3B4EQW6
names: Similarity
messages: Belongs to the CD36 family.

42514:ppp6c
gene id: 42514:ppp6c
uniprot id: A0A3B4DJV5
names: Similarity
messages: Belongs to the PPP phosphatase family.

42514:LOC108413448
gene id: 42514:LOC108413448
uniprot id: A0A3B4E8B7
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

42514:dcp1a
gene id: 42514:dcp1a
uniprot id: A0A3B4DSY1
names: Similarity
messages: Belongs to the DCP1 family.

42514:LOC108424776
gene id: 42514:LOC108424776
uniprot id: A0A3B4ELB8
names: Subcellular Location Annotation
messages: Nucleus

42514:cenpt
gene id: 42514:cenpt
uniprot id: A0A3B4DHM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus

42514:ep300a
gene id: 42514:ep300a
uniprot id: A0A3B4E892
names: Subcellular Location Annotation
messages: Cytoplasm

42514:exosc1
gene id: 42514:exosc1
uniprot id: A0A3B4C3M4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:slc4a10a
gene id: 42514:slc4a10a
uniprot id: A0A3B4C9F6
uniprot id: A0A3B4DYX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

42514:LOC108441721
gene id: 42514:LOC108441721
uniprot id: A0A3B4CNM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:nr1d4b
gene id: 42514:nr1d4b
uniprot id: A0A3B4DFH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:LOC108435091
gene id: 42514:LOC108435091
uniprot id: A0A3B4C8W7
names: Similarity
messages: Belongs to the TGF-beta family.

42514:dtnbb
gene id: 42514:dtnbb
uniprot id: A0A3B4CFC7
uniprot id: A0A3B4DZK6
uniprot id: A0A3B4E3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

42514:hsd17b7
gene id: 42514:hsd17b7
uniprot id: A0A3B4DQZ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

42514:casp23
gene id: 42514:casp23
uniprot id: A0A3B4C1Z8
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:LOC108426823
gene id: 42514:LOC108426823
uniprot id: A0A3B4DYS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

42514:LOC108439989
gene id: 42514:LOC108439989
uniprot id: A0A3B4EFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:enkur
gene id: 42514:enkur
uniprot id: A0A3B4DGA8
names: Subcellular Location Annotation
messages: cilium axoneme

42514:slc35b2
gene id: 42514:slc35b2
uniprot id: A0A3B4C543
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

42514:cacng3b
gene id: 42514:cacng3b
uniprot id: A0A3B4CAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

42514:psmd5
gene id: 42514:psmd5
uniprot id: A0A3B4E6K8
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

42514:chrna4b
gene id: 42514:chrna4b
uniprot id: A0A3B4C520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:tmem245
gene id: 42514:tmem245
uniprot id: A0A3B4D8L6
uniprot id: A0A3B4D910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

42514:LOC108443950
gene id: 42514:LOC108443950
uniprot id: A0A3B4EMT2
names: Similarity
messages: Belongs to the SEC6 family.

42514:LOC108432824
gene id: 42514:LOC108432824
uniprot id: A0A3B4EC51
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:tenm4
gene id: 42514:tenm4
uniprot id: A0A3B4C179
uniprot id: A0A3B4DRU1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:zdhhc6
gene id: 42514:zdhhc6
uniprot id: A0A3B4DCD4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:LOC108440004
gene id: 42514:LOC108440004
uniprot id: A0A3B4D281
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:plppr5b
gene id: 42514:plppr5b
uniprot id: A0A3B4CUG6
uniprot id: A0A3B4CWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:mfsd9
gene id: 42514:mfsd9
uniprot id: A0A3B4BTY2
names: Subcellular Location Annotation
messages: Membrane

42514:adcy3a
gene id: 42514:adcy3a
uniprot id: A0A3B4DPT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:ints7
gene id: 42514:ints7
uniprot id: A0A3B4DRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus

42514:tph1a
gene id: 42514:tph1a
uniprot id: A0A3B4DI33
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

42514:epb41b
gene id: 42514:epb41b
uniprot id: A0A3B4EJK0
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex

42514:fam20a
gene id: 42514:fam20a
uniprot id: A0A3B4C728
names: Similarity
messages: Belongs to the FAM20 family.

42514:pde4d
gene id: 42514:pde4d
uniprot id: A0A3B4CD14
uniprot id: A0A3B4E0S3
uniprot id: A0A3B4E0Z6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:LOC108433151
gene id: 42514:LOC108433151
uniprot id: A0A3B4DQ93
names: Subcellular Location Annotation
messages: Membrane

42514:flot2b
gene id: 42514:flot2b
uniprot id: A0A3B4CN87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

42514:elovl6
gene id: 42514:elovl6
uniprot id: A0A3B4CTC7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

42514:si:ch73-382f3.1
gene id: 42514:si:ch73-382f3.1
uniprot id: A0A3B4CWW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

42514:rpl18a
gene id: 42514:rpl18a
uniprot id: A0A3B4DN18
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

42514:arl3b
gene id: 42514:arl3b
uniprot id: A0A3B4D7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

42514:med13b
gene id: 42514:med13b
uniprot id: A0A3B4CAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:LOC108412458
gene id: 42514:LOC108412458
uniprot id: A0A3B4DPA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

42514:gjc4b
gene id: 42514:gjc4b
uniprot id: A0A3B4CAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:LOC108435610
gene id: 42514:LOC108435610
uniprot id: A0A3B4EFN3
uniprot id: A0A3B4EFN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

42514:gpr183a
gene id: 42514:gpr183a
uniprot id: A0A3B4D190
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:rem1
gene id: 42514:rem1
uniprot id: A0A3B4DK24
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

42514:unkl
gene id: 42514:unkl
uniprot id: A0A3B4BW87
uniprot id: A0A3B4DQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

42514:slc4a1a
gene id: 42514:slc4a1a
uniprot id: A0A3B4CB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

42514:aars2
gene id: 42514:aars2
uniprot id: A0A3B4EJ25
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

42514:LOC108412723
gene id: 42514:LOC108412723
uniprot id: A0A3B4D930
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse

42514:ptger4c
gene id: 42514:ptger4c
uniprot id: A0A3B4BWQ9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:itgae.2
gene id: 42514:itgae.2
uniprot id: A0A3B4D623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:inpp1
gene id: 42514:inpp1
uniprot id: A0A3B4DLD6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

42514:mrps25
gene id: 42514:mrps25
uniprot id: A0A3B4BNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

42514:LOC108413118
gene id: 42514:LOC108413118
uniprot id: A0A3B4DPC3
names: Similarity
messages: Belongs to the intermediate filament family.

42514:ttc21a
gene id: 42514:ttc21a
uniprot id: A0A3B4EKL1
names: Similarity
messages: Belongs to the TTC21 family.

42514:metap2b
gene id: 42514:metap2b
uniprot id: A0A3B4DHE8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

42514:rab18b
gene id: 42514:rab18b
uniprot id: A0A3B4DW63
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

42514:fmoda
gene id: 42514:fmoda
uniprot id: A0A3B4BXI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

42514:edil3b
gene id: 42514:edil3b
uniprot id: A0A3B4BUX4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108436379
gene id: 42514:LOC108436379
uniprot id: A0A3B4C225
uniprot id: A0A3B4C5T4
names: Subcellular Location Annotation
messages: Nucleus

42514:dennd5a
gene id: 42514:dennd5a
uniprot id: A0A3B4EMT5
uniprot id: A0A3B4EN46
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:kif22
gene id: 42514:kif22
uniprot id: A0A3B4C699
uniprot id: A0A3B4DUS0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:pxmp4
gene id: 42514:pxmp4
uniprot id: A0A3B4DHH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

42514:rab3db
gene id: 42514:rab3db
uniprot id: A0A3B4BTJ3
uniprot id: A0A3B4DLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

42514:dner
gene id: 42514:dner
uniprot id: A0A3B4BNG5
uniprot id: A0A3B4BP13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108415319
gene id: 42514:LOC108415319
uniprot id: A0A3B4DLU6
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:rpp14
gene id: 42514:rpp14
uniprot id: A0A3B4DHC6
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

42514:itga6b
gene id: 42514:itga6b
uniprot id: A0A3B4BVC5
uniprot id: A0A3B4DPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:pyya
gene id: 42514:pyya
uniprot id: A0A3B4EPB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

42514:LOC108432943
gene id: 42514:LOC108432943
uniprot id: A0A3B4CSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

42514:kat7b
gene id: 42514:kat7b
uniprot id: A0A3B4DFD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

42514:pim1
gene id: 42514:pim1
uniprot id: A0A3B4CE15
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

42514:pla1a
gene id: 42514:pla1a
uniprot id: A0A3B4C175
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

42514:timm10
gene id: 42514:timm10
uniprot id: A0A3B4E0A1
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

42514:snx33
gene id: 42514:snx33
uniprot id: A0A3B4BQ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

42514:ache
gene id: 42514:ache
uniprot id: A0A3B4E5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

42514:plk3
gene id: 42514:plk3
uniprot id: A0A3B4DZQ9
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

42514:slc9a8
gene id: 42514:slc9a8
uniprot id: A0A3B4D2L7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

42514:LOC108431254
gene id: 42514:LOC108431254
uniprot id: A0A3B4DVB0
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108412991
gene id: 42514:LOC108412991
uniprot id: A0A3B4DYP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

42514:cers4b
gene id: 42514:cers4b
uniprot id: A0A3B4EIY9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

42514:peli1b
gene id: 42514:peli1b
uniprot id: A0A3B4EKL5
names: Similarity
messages: Belongs to the pellino family.

42514:pan2
gene id: 42514:pan2
uniprot id: A0A3B4DB98
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

42514:sigmar1
gene id: 42514:sigmar1
uniprot id: A0A3B4EJB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

42514:ddit3
gene id: 42514:ddit3
uniprot id: A0A3B4E1D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

42514:polr2c
gene id: 42514:polr2c
uniprot id: A0A3B4C2D3
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

42514:LOC108441838
gene id: 42514:LOC108441838
uniprot id: A0A3B4BVA9
uniprot id: A0A3B4DNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

42514:foxf2a
gene id: 42514:foxf2a
uniprot id: A0A3B4DE54
names: Subcellular Location Annotation
messages: Nucleus

42514:atxn2
gene id: 42514:atxn2
uniprot id: A0A3B4DQF9
names: Similarity
messages: Belongs to the ataxin-2 family.

42514:gdf3
gene id: 42514:gdf3
uniprot id: A0A3B4BP05
names: Similarity
messages: Belongs to the TGF-beta family.

42514:tiprl
gene id: 42514:tiprl
uniprot id: A0A3B4E659
names: Similarity
messages: Belongs to the TIP41 family.

42514:vps37c
gene id: 42514:vps37c
uniprot id: A0A3B4E5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

42514:zgc:153409
gene id: 42514:zgc:153409
uniprot id: A0A3B4EQP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:llph
gene id: 42514:llph
uniprot id: A0A3B4BW39
names: Similarity
messages: Belongs to the learning-associated protein family.

42514:fmnl1b
gene id: 42514:fmnl1b
uniprot id: A0A3B4DVV2
uniprot id: A0A3B4DZX4
names: Similarity
messages: Belongs to the formin homology family.

42514:lhx5
gene id: 42514:lhx5
uniprot id: A0A3B4CHV2
names: Subcellular Location Annotation
messages: Nucleus

42514:sema3fa
gene id: 42514:sema3fa
uniprot id: A0A3B4C550
uniprot id: A0A3B4DTW1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tceanc2
gene id: 42514:tceanc2
uniprot id: A0A3B4EMD3
names: Subcellular Location Annotation
messages: Nucleus

42514:zfhx4
gene id: 42514:zfhx4
uniprot id: A0A3B4CYW9
uniprot id: A0A3B4CZJ0
names: Subcellular Location Annotation
messages: Nucleus

42514:mrpl49
gene id: 42514:mrpl49
uniprot id: A0A3B4ENZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

42514:antkmt
gene id: 42514:antkmt
uniprot id: A0A3B4DJS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

42514:amt
gene id: 42514:amt
uniprot id: A0A3B4CJC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvT family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

42514:tmem50a
gene id: 42514:tmem50a
uniprot id: A0A3B4CGJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

42514:ahcyl1
gene id: 42514:ahcyl1
uniprot id: A0A3B4BPN5
uniprot id: A0A3B4BPR1
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

42514:man1b1a
gene id: 42514:man1b1a
uniprot id: A0A3B4ENE2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:zgc:113425
gene id: 42514:zgc:113425
uniprot id: A0A3B4DEG9
names: Similarity
messages: Belongs to the MS4A family.

42514:kdm5ba
gene id: 42514:kdm5ba
uniprot id: A0A3B4E1W0
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

42514:calr3a
gene id: 42514:calr3a
uniprot id: A0A3B4E595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

42514:synpr
gene id: 42514:synpr
uniprot id: A0A3B4CA62
uniprot id: A0A3B4CC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:mboat2b
gene id: 42514:mboat2b
uniprot id: A0A3B4EBG8
names: Subcellular Location Annotation
messages: Membrane

42514:dph6
gene id: 42514:dph6
uniprot id: A0A3B4DLB4
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

42514:aclya
gene id: 42514:aclya
uniprot id: A0A3B4DBL0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

42514:c26h1orf74
gene id: 42514:c26h1orf74
uniprot id: A0A3B4CK69
names: Similarity
messages: Belongs to the UPF0739 family.

42514:LOC108423545
gene id: 42514:LOC108423545
uniprot id: A0A3B4DHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

42514:cln8
gene id: 42514:cln8
uniprot id: A0A3B4D2D4
names: Subcellular Location Annotation
messages: Membrane

42514:avpr1ab
gene id: 42514:avpr1ab
uniprot id: A0A3B4DPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:LOC108442655
gene id: 42514:LOC108442655
uniprot id: A0A3B4DIV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:fgd1
gene id: 42514:fgd1
uniprot id: A0A3B4D464
names: Subcellular Location Annotation
messages: cytoskeleton

42514:sybu
gene id: 42514:sybu
uniprot id: A0A3B4BZC8
names: Subcellular Location Annotation
messages: Membrane

42514:adgrl2a
gene id: 42514:adgrl2a
uniprot id: A0A3B4CF14
names: Subcellular Location Annotation
messages: Membrane

42514:syt2a
gene id: 42514:syt2a
uniprot id: A0A3B4BZ69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

42514:odc1
gene id: 42514:odc1
uniprot id: A0A3B4BZP8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

42514:agxta
gene id: 42514:agxta
uniprot id: A0A3B4EQP5
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

42514:rps19bp1
gene id: 42514:rps19bp1
uniprot id: A0A3B4BNS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

42514:LOC108414084
gene id: 42514:LOC108414084
uniprot id: A0A3B4BP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:mllt11
gene id: 42514:mllt11
uniprot id: A0A3B4BRX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

42514:mfn2
gene id: 42514:mfn2
uniprot id: A0A3B4EKD3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

42514:sgms2a
gene id: 42514:sgms2a
uniprot id: A0A3B4CPZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

42514:bola1
gene id: 42514:bola1
uniprot id: A0A3B4DDV6
names: Similarity
messages: Belongs to the BolA/IbaG family.

42514:ttyh2l
gene id: 42514:ttyh2l
uniprot id: A0A3B4EDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

42514:pa2g4b
gene id: 42514:pa2g4b
uniprot id: A0A3B4CUS1
names: Similarity
messages: Belongs to the peptidase M24 family.

42514:c12h19orf53
gene id: 42514:c12h19orf53
uniprot id: A0A3B4DUL4
names: Similarity
messages: Belongs to the UPF0390 family.

42514:LOC108440860
gene id: 42514:LOC108440860
uniprot id: A0A3B4C281
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:nop58
gene id: 42514:nop58
uniprot id: A0A3B4CXY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

42514:clul1
gene id: 42514:clul1
uniprot id: A0A3B4DA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

42514:fam53b
gene id: 42514:fam53b
uniprot id: A0A3B4DAE1
names: Similarity
messages: Belongs to the FAM53 family.

42514:asip2b
gene id: 42514:asip2b
uniprot id: A0A3B4CLA6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:si:ch73-374l24.1
gene id: 42514:si:ch73-374l24.1
uniprot id: A0A3B4EP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

42514:rspo4
gene id: 42514:rspo4
uniprot id: A0A3B4DVI6
names: Similarity
messages: Belongs to the R-spondin family.

42514:nkiras1
gene id: 42514:nkiras1
uniprot id: A0A3B4BVS1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

42514:adgrv1
gene id: 42514:adgrv1
uniprot id: A0A3B4DW60
names: Subcellular Location Annotation
messages: Membrane

42514:cldn15a
gene id: 42514:cldn15a
uniprot id: A0A3B4E9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:heg1
gene id: 42514:heg1
uniprot id: A0A3B4DVF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:strn3
gene id: 42514:strn3
uniprot id: A0A3B4CQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

42514:rapgef4a
gene id: 42514:rapgef4a
uniprot id: A0A3B4CVJ8
uniprot id: A0A3B4E7C0
names: Similarity
messages: Belongs to the RAPGEF2 family.

42514:rpl23
gene id: 42514:rpl23
uniprot id: A0A3B4EPJ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

42514:gdf10a
gene id: 42514:gdf10a
uniprot id: A0A3B4DIC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

42514:etv5b
gene id: 42514:etv5b
uniprot id: A0A3B4CR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:pycr1b
gene id: 42514:pycr1b
uniprot id: A0A3B4BLG5
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

42514:abi2a
gene id: 42514:abi2a
uniprot id: A0A3B4BXR6
uniprot id: A0A3B4BXW2
uniprot id: A0A3B4C183
uniprot id: A0A3B4DMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

42514:grk5
gene id: 42514:grk5
uniprot id: A0A3B4D851
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:ccka
gene id: 42514:ccka
uniprot id: A0A3B4ECK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

42514:LOC108414446
gene id: 42514:LOC108414446
uniprot id: A0A3B4D5S3
names: Subcellular Location Annotation
messages: Membrane

42514:myod1
gene id: 42514:myod1
uniprot id: A0A3B4ENT0
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

42514:vamp1
gene id: 42514:vamp1
uniprot id: A0A3B4DXA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

42514:fosab
gene id: 42514:fosab
uniprot id: A0A3B4CSV1
names: Similarity
messages: Belongs to the bZIP family. Fos subfamily.

42514:si:dkey-174m14.3
gene id: 42514:si:dkey-174m14.3
uniprot id: A0A3B4BLJ8
names: Subcellular Location Annotation
messages: Membrane

42514:adcyap1b
gene id: 42514:adcyap1b
uniprot id: A0A3B4D6C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

42514:mfng
gene id: 42514:mfng
uniprot id: A0A3B4EBC4
names: Subcellular Location Annotation
messages: Membrane

42514:rab27b
gene id: 42514:rab27b
uniprot id: A0A3B4CPF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

42514:otud7b
gene id: 42514:otud7b
uniprot id: A0A3B4DD99
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:fam20ca
gene id: 42514:fam20ca
uniprot id: A0A3B4CJ58
names: Similarity
messages: Belongs to the FAM20 family.

42514:nat15
gene id: 42514:nat15
uniprot id: A0A3B4EC72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

42514:ube2t
gene id: 42514:ube2t
uniprot id: A0A3B4CV48
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:c7h19orf54
gene id: 42514:c7h19orf54
uniprot id: A0A3B4DCI9
names: Similarity
messages: Belongs to the UPF0692 family.

42514:stx5al
gene id: 42514:stx5al
uniprot id: A0A3B4C214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

42514:LOC108441869
gene id: 42514:LOC108441869
uniprot id: A0A3B4DX33
names: Subcellular Location Annotation
messages: Membrane

42514:ccnb3
gene id: 42514:ccnb3
uniprot id: A0A3B4D759
uniprot id: A0A3B4D830
names: Similarity
messages: Belongs to the cyclin family.

42514:LOC108429244
gene id: 42514:LOC108429244
uniprot id: A0A3B4DP45
uniprot id: A0A3B4DP61
uniprot id: A0A3B4DSQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:trmt2b
gene id: 42514:trmt2b
uniprot id: A0A3B4BRV5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:si:dkey-110c1.10
gene id: 42514:si:dkey-110c1.10
uniprot id: A0A3B4E5P6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:triap1
gene id: 42514:triap1
uniprot id: A0A3B4E7W4
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

42514:st8sia1
gene id: 42514:st8sia1
uniprot id: A0A3B4DDL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:ssh1b
gene id: 42514:ssh1b
uniprot id: A0A3B4BP48
uniprot id: A0A3B4DJP5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

42514:LOC108438107
gene id: 42514:LOC108438107
uniprot id: A0A3B4ECZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

42514:wt1a
gene id: 42514:wt1a
uniprot id: A0A3B4BL58
uniprot id: A0A3B4BPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

42514:chst1
gene id: 42514:chst1
uniprot id: A0A3B4C1S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:ada
gene id: 42514:ada
uniprot id: A0A3B4CRM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

42514:map2k4a
gene id: 42514:map2k4a
uniprot id: A0A3B4CQG9
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108435845
gene id: 42514:LOC108435845
uniprot id: A0A3B4C8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:rab38b
gene id: 42514:rab38b
uniprot id: A0A3B4E1Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

42514:snx9b
gene id: 42514:snx9b
uniprot id: A0A3B4C7U2
uniprot id: A0A3B4C8M8
uniprot id: A0A3B4DUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

42514:slc29a1b
gene id: 42514:slc29a1b
uniprot id: A0A3B4BNB7
uniprot id: A0A3B4BR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

42514:slc35b3
gene id: 42514:slc35b3
uniprot id: A0A3B4D643
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

42514:ptger4b
gene id: 42514:ptger4b
uniprot id: A0A3B4CVU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

42514:LOC108432831
gene id: 42514:LOC108432831
uniprot id: A0A3B4E8Y9
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108437516
gene id: 42514:LOC108437516
uniprot id: A0A3B4CIR9
names: Subcellular Location Annotation
messages: Membrane

42514:ikbkb
gene id: 42514:ikbkb
uniprot id: A0A3B4BLN7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:tcf25
gene id: 42514:tcf25
uniprot id: A0A3B4D9Q6
names: Similarity
messages: Belongs to the TCF25 family.

42514:rpp30
gene id: 42514:rpp30
uniprot id: A0A3B4E0U5
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

42514:tulp4b
gene id: 42514:tulp4b
uniprot id: A0A3B4BN00
names: Similarity
messages: Belongs to the TUB family.

42514:LOC108414844
gene id: 42514:LOC108414844
uniprot id: A0A3B4C8L8
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion intermembrane space
messages: Mitochondrion outer membrane
messages: Rough endoplasmic reticulum
messages: cilium
messages: extracellular exosome
messages: extracellular space

42514:mpg
gene id: 42514:mpg
uniprot id: A0A3B4DTX7
names: Function
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.
messages: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

42514:ogfr
gene id: 42514:ogfr
uniprot id: A0A3B4D585
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

42514:nfe2l1b
gene id: 42514:nfe2l1b
uniprot id: A0A3B4DJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

42514:tomt
gene id: 42514:tomt
uniprot id: A0A3B4BNY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum

42514:ap3m1
gene id: 42514:ap3m1
uniprot id: A0A3B4CC58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.

42514:ccdc103
gene id: 42514:ccdc103
uniprot id: A0A3B4DGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

42514:fam91a1
gene id: 42514:fam91a1
uniprot id: A0A3B4DQ96
names: Similarity
messages: Belongs to the FAM91 family.

42514:dyrk3
gene id: 42514:dyrk3
uniprot id: A0A3B4C0H0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:dnajc18
gene id: 42514:dnajc18
uniprot id: A0A3B4DU45
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108412762
gene id: 42514:LOC108412762
uniprot id: A0A3B4EDF8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

42514:si:ch211-168f7.5
gene id: 42514:si:ch211-168f7.5
uniprot id: A0A3B4D1W6
names: Similarity
messages: Belongs to the dapper family.

42514:LOC108440755
gene id: 42514:LOC108440755
uniprot id: A0A3B4DYB4
names: Subcellular Location Annotation
messages: Nucleus

42514:fbp2
gene id: 42514:fbp2
uniprot id: A0A3B4CBZ5
names: Similarity
messages: Belongs to the FBPase class 1 family.

42514:LOC108441018
gene id: 42514:LOC108441018
uniprot id: A0A3B4BSK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

42514:panx3
gene id: 42514:panx3
uniprot id: A0A3B4CPT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

42514:zgc:110789
gene id: 42514:zgc:110789
uniprot id: A0A3B4CUR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

42514:rpl10
gene id: 42514:rpl10
uniprot id: A0A3B4CB39
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

42514:chaf1a
gene id: 42514:chaf1a
uniprot id: A0A3B4CN46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHAF1A family.
messages: Nucleus

42514:b3galt2
gene id: 42514:b3galt2
uniprot id: A0A3B4DM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:smarcd2
gene id: 42514:smarcd2
uniprot id: A0A3B4C4Q3
names: Similarity
messages: Belongs to the SMARCD family.

42514:LOC108424795
gene id: 42514:LOC108424795
uniprot id: A0A3B4DDG4
uniprot id: A0A3B4EL37
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

42514:adamts18
gene id: 42514:adamts18
uniprot id: A0A3B4CXT6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:vamp8
gene id: 42514:vamp8
uniprot id: A0A3B4D1U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

42514:endou
gene id: 42514:endou
uniprot id: A0A3B4DZQ8
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

42514:sppl2
gene id: 42514:sppl2
uniprot id: A0A3B4DPF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

42514:LOC108414297
gene id: 42514:LOC108414297
uniprot id: A0A3B4BNP8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:LOC108436449
gene id: 42514:LOC108436449
uniprot id: A0A3B4BZ47
uniprot id: A0A3B4BZ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

42514:plppr3a
gene id: 42514:plppr3a
uniprot id: A0A3B4DU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:neil3
gene id: 42514:neil3
uniprot id: A0A3B4EA79
names: Similarity
messages: Belongs to the FPG family.

42514:grk6
gene id: 42514:grk6
uniprot id: A0A3B4CJ72
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:LOC108411422
gene id: 42514:LOC108411422
uniprot id: A0A3B4DIP4
names: Subcellular Location Annotation
messages: Membrane

42514:lin7a
gene id: 42514:lin7a
uniprot id: A0A3B4C6M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

42514:LOC108436452
gene id: 42514:LOC108436452
uniprot id: A0A3B4BUI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

42514:stxbp1b
gene id: 42514:stxbp1b
uniprot id: A0A3B4EC65
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

42514:fam219ab
gene id: 42514:fam219ab
uniprot id: A0A3B4EG08
names: Similarity
messages: Belongs to the FAM219 family.

42514:fbxo9
gene id: 42514:fbxo9
uniprot id: A0A3B4CYZ1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:mrrf
gene id: 42514:mrrf
uniprot id: A0A3B4CKV4
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

42514:cplx3a
gene id: 42514:cplx3a
uniprot id: A0A3B4E8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

42514:anapc16
gene id: 42514:anapc16
uniprot id: A0A3B4BUS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

42514:stmn1a
gene id: 42514:stmn1a
uniprot id: A0A3B4DNS3
names: Similarity
messages: Belongs to the stathmin family.

42514:rbfox3a
gene id: 42514:rbfox3a
uniprot id: A0A3B4C7W7
uniprot id: A0A3B4C9X4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

42514:sec16b
gene id: 42514:sec16b
uniprot id: A0A3B4BR92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

42514:stmn4l
gene id: 42514:stmn4l
uniprot id: A0A3B4DQA5
names: Similarity
messages: Belongs to the stathmin family.

42514:LOC108415398
gene id: 42514:LOC108415398
uniprot id: A0A3B4E6M8
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

42514:rft1
gene id: 42514:rft1
uniprot id: A0A3B4E3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

42514:LOC108412050
gene id: 42514:LOC108412050
uniprot id: A0A3B4DCN6
names: Similarity
messages: Belongs to the CD225/Dispanin family.

42514:arrb2b
gene id: 42514:arrb2b
uniprot id: A0A3B4CN88
names: Similarity
messages: Belongs to the arrestin family.

42514:LOC108429582
gene id: 42514:LOC108429582
uniprot id: A0A3B4E8G8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108443144
gene id: 42514:LOC108443144
uniprot id: A0A3B4DPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

42514:ppa1a
gene id: 42514:ppa1a
uniprot id: A0A3B4BR81
names: Similarity
messages: Belongs to the PPase family.

42514:top2a
gene id: 42514:top2a
uniprot id: A0A3B4DIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

42514:LOC108432876
gene id: 42514:LOC108432876
uniprot id: A0A3B4CYC9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:slc6a6b
gene id: 42514:slc6a6b
uniprot id: A0A3B4D5M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

42514:rgs2
gene id: 42514:rgs2
uniprot id: A0A3B4EQA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

42514:LOC108426241
gene id: 42514:LOC108426241
uniprot id: A0A3B4DX45
names: Similarity
messages: Belongs to the arrestin family.

42514:paqr3a
gene id: 42514:paqr3a
uniprot id: A0A3B4CSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:LOC108429253
gene id: 42514:LOC108429253
uniprot id: A0A3B4BYN2
names: Subcellular Location Annotation
messages: Membrane

42514:hck
gene id: 42514:hck
uniprot id: A0A3B4BT50
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:znf703
gene id: 42514:znf703
uniprot id: A0A3B4BPL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

42514:acmsd
gene id: 42514:acmsd
uniprot id: A0A3B4EKX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

42514:LOC108436233
gene id: 42514:LOC108436233
uniprot id: A0A3B4CIR1
uniprot id: A0A3B4CIS5
uniprot id: A0A3B4E0V1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

42514:LOC108433477
gene id: 42514:LOC108433477
uniprot id: A0A3B4E797
names: Caution
names: Similarity
messages: Belongs to the Ntn-hydrolase family.
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:sf3b4
gene id: 42514:sf3b4
uniprot id: A0A3B4DJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

42514:spast
gene id: 42514:spast
uniprot id: A0A3B4CEM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. Also plays a role in axon growth and the formation of axonal branches.
messages: Belongs to the AAA ATPase family. Spastin subfamily.
messages: Homohexamer. The homohexamer is stabilized by ATP-binding. The homohexamer may adopt a ring conformation through which microtubules pass prior to being severed. Interacts with microtubules.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cytoskeleton
messages: perinuclear region

42514:ptp4a2b
gene id: 42514:ptp4a2b
uniprot id: A0A3B4DNC0
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

42514:csk
gene id: 42514:csk
uniprot id: A0A3B4CTE4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:pabpc1b
gene id: 42514:pabpc1b
uniprot id: A0A3B4D580
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

42514:ldhbb
gene id: 42514:ldhbb
uniprot id: A0A3B4EN28
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

42514:si:ch1073-157b13.1
gene id: 42514:si:ch1073-157b13.1
uniprot id: A0A3B4C5S9
names: Similarity
messages: Belongs to the methyltransferase superfamily.

42514:zfp36l1a
gene id: 42514:zfp36l1a
uniprot id: A0A3B4CI79
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:mcm10
gene id: 42514:mcm10
uniprot id: A0A3B4EPB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

42514:zgc:198371
gene id: 42514:zgc:198371
uniprot id: A0A3B4EC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:slc6a8
gene id: 42514:slc6a8
uniprot id: A0A3B4D4G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:tspan15
gene id: 42514:tspan15
uniprot id: A0A3B4EEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:qsox1
gene id: 42514:qsox1
uniprot id: A0A3B4CL65
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

42514:foxj1a
gene id: 42514:foxj1a
uniprot id: A0A3B4D118
names: Subcellular Location Annotation
messages: Nucleus

42514:nol12
gene id: 42514:nol12
uniprot id: A0A3B4EEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

42514:tipin
gene id: 42514:tipin
uniprot id: A0A3B4DZ05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

42514:barhl1b
gene id: 42514:barhl1b
uniprot id: A0A3B4EFA7
names: Subcellular Location Annotation
messages: Nucleus

42514:avl9
gene id: 42514:avl9
uniprot id: A0A3B4C0S6
names: Subcellular Location Annotation
messages: Endosome
messages: Recycling endosome

42514:tcn2
gene id: 42514:tcn2
uniprot id: A0A3B4C078
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

42514:LOC108441379
gene id: 42514:LOC108441379
uniprot id: A0A3B4C529
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

42514:api5
gene id: 42514:api5
uniprot id: A0A3B4CFR0
names: Similarity
messages: Belongs to the API5 family.

42514:bet1l
gene id: 42514:bet1l
uniprot id: A0A3B4DHP0
names: Subcellular Location Annotation
messages: Membrane

42514:bloc1s5
gene id: 42514:bloc1s5
uniprot id: A0A3B4D3Z3
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

42514:LOC108439021
gene id: 42514:LOC108439021
uniprot id: A0A3B4CLA7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108413049
gene id: 42514:LOC108413049
uniprot id: A0A3B4DRA9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

42514:mapre2
gene id: 42514:mapre2
uniprot id: A0A3B4C4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

42514:alx1
gene id: 42514:alx1
uniprot id: A0A3B4CMQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

42514:LOC108427396
gene id: 42514:LOC108427396
uniprot id: A0A3B4CIT0
names: Similarity
messages: Belongs to the intermediate filament family.

42514:brcc3
gene id: 42514:brcc3
uniprot id: A0A3B4EJ64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M67A family. BRCC36 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Component of the BRCA1-A complex. Component of the BRISC complex. Both the BRCA1-A complex and the BRISC complex bind polyubiquitin.
messages: Cytoplasm
messages: Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1.
messages: Nucleus
messages: spindle pole

42514:efhc2
gene id: 42514:efhc2
uniprot id: A0A3B4EF34
names: Subcellular Location Annotation
messages: cilium axoneme

42514:slc33a1
gene id: 42514:slc33a1
uniprot id: A0A3B4CCS9
names: Subcellular Location Annotation
messages: Membrane

42514:klhl22
gene id: 42514:klhl22
uniprot id: A0A3B4CU76
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

42514:ube2g2
gene id: 42514:ube2g2
uniprot id: A0A3B4DMI2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:foxj1b
gene id: 42514:foxj1b
uniprot id: A0A3B4DP11
names: Subcellular Location Annotation
messages: Nucleus

42514:ccser2b
gene id: 42514:ccser2b
uniprot id: A0A3B4EIY0
names: Similarity
messages: Belongs to the CCSER family.

42514:pane1
gene id: 42514:pane1
uniprot id: A0A3B4C4U8
names: Subcellular Location Annotation
messages: Nucleus

42514:lamp1b
gene id: 42514:lamp1b
uniprot id: A0A3B4EES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

42514:LOC108430556
gene id: 42514:LOC108430556
uniprot id: A0A3B4EFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

42514:mad1l1
gene id: 42514:mad1l1
uniprot id: A0A3B4C4R9
names: Similarity
messages: Belongs to the MAD1 family.

42514:necap1
gene id: 42514:necap1
uniprot id: A0A3B4DAY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

42514:sar1ab
gene id: 42514:sar1ab
uniprot id: A0A3B4BRR0
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

42514:fgfbp1a
gene id: 42514:fgfbp1a
uniprot id: A0A3B4ELV1
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

42514:ldlrad4a
gene id: 42514:ldlrad4a
uniprot id: A0A3B4EK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

42514:senp6a
gene id: 42514:senp6a
uniprot id: A0A3B4CAC5
uniprot id: A0A3B4DYD0
uniprot id: A0A3B4DZZ6
names: Similarity
messages: Belongs to the peptidase C48 family.

42514:snap25a
gene id: 42514:snap25a
uniprot id: A0A3B4EMM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

42514:LOC108427446
gene id: 42514:LOC108427446
uniprot id: A0A3B4CE19
names: Similarity
messages: Belongs to the RASGRP family.

42514:LOC108432685
gene id: 42514:LOC108432685
uniprot id: A0A3B4DJ11
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:hnrnpub
gene id: 42514:hnrnpub
uniprot id: A0A3B4BQK1
names: Subcellular Location Annotation
messages: Nucleus

42514:il2rb
gene id: 42514:il2rb
uniprot id: A0A3B4CP31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane

42514:ckmt2a
gene id: 42514:ckmt2a
uniprot id: A0A3B4C6U3
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

42514:aplp2
gene id: 42514:aplp2
uniprot id: A0A3B4C7D5
uniprot id: A0A3B4C9H8
uniprot id: A0A3B4C9K6
uniprot id: A0A3B4DWY5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:chmp2bb
gene id: 42514:chmp2bb
uniprot id: A0A3B4EI36
names: Similarity
messages: Belongs to the SNF7 family.

42514:tmem254
gene id: 42514:tmem254
uniprot id: A0A3B4C7A0
names: Subcellular Location Annotation
messages: Membrane

42514:sstr2a
gene id: 42514:sstr2a
uniprot id: A0A3B4EEA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

42514:tlcd3a
gene id: 42514:tlcd3a
uniprot id: A0A3B4EQY4
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108432863
gene id: 42514:LOC108432863
uniprot id: A0A3B4EAS5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108436916
gene id: 42514:LOC108436916
uniprot id: A0A3B4E2C2
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

42514:tmed2
gene id: 42514:tmed2
uniprot id: A0A3B4C914
uniprot id: A0A3B4DV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

42514:phf19
gene id: 42514:phf19
uniprot id: A0A3B4D1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

42514:ptgs1
gene id: 42514:ptgs1
uniprot id: A0A3B4D9Z7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108410535
gene id: 42514:LOC108410535
uniprot id: A0A3B4CTA8
names: Subcellular Location Annotation
messages: Membrane

42514:capn9
gene id: 42514:capn9
uniprot id: A0A3B4E5I7
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:enpp5
gene id: 42514:enpp5
uniprot id: A0A3B4ELQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

42514:si:ch73-196l6.5
gene id: 42514:si:ch73-196l6.5
uniprot id: A0A3B4CZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

42514:grb2b
gene id: 42514:grb2b
uniprot id: A0A3B4BP58
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

42514:LOC108443059
gene id: 42514:LOC108443059
uniprot id: A0A3B4C5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:slc48a1a
gene id: 42514:slc48a1a
uniprot id: A0A3B4EDJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment.
messages: Lysosome membrane
messages: Membrane

42514:rnf10
gene id: 42514:rnf10
uniprot id: A0A3B4DW82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF10 family.
messages: Cytoplasm

42514:LOC108439997
gene id: 42514:LOC108439997
uniprot id: A0A3B4EFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:antxr2b
gene id: 42514:antxr2b
uniprot id: A0A3B4CML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

42514:LOC108411836
gene id: 42514:LOC108411836
uniprot id: A0A3B4CCQ2
names: Subcellular Location Annotation
messages: Membrane

42514:mesd
gene id: 42514:mesd
uniprot id: A0A3B4C2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

42514:slc27a4
gene id: 42514:slc27a4
uniprot id: A0A3B4CIQ2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:rspo2
gene id: 42514:rspo2
uniprot id: A0A3B4C1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

42514:uncx4.1
gene id: 42514:uncx4.1
uniprot id: A0A3B4DJI9
names: Subcellular Location Annotation
messages: Nucleus

42514:hoxd4a
gene id: 42514:hoxd4a
uniprot id: A0A3B4E8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:tnfsf14
gene id: 42514:tnfsf14
uniprot id: A0A3B4CP16
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:LOC108438832
gene id: 42514:LOC108438832
uniprot id: A0A3B4D983
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

42514:scamp4
gene id: 42514:scamp4
uniprot id: A0A3B4CIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

42514:LOC108423891
gene id: 42514:LOC108423891
uniprot id: A0A3B4CE61
names: Similarity
messages: Belongs to the beta-catenin family.

42514:tfe3a
gene id: 42514:tfe3a
uniprot id: A0A3B4EIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

42514:timm17a
gene id: 42514:timm17a
uniprot id: A0A3B4CF60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

42514:flcn
gene id: 42514:flcn
uniprot id: A0A3B4CPQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

42514:chrm3a
gene id: 42514:chrm3a
uniprot id: A0A3B4DAG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

42514:LOC108429320
gene id: 42514:LOC108429320
uniprot id: A0A3B4EN67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

42514:mettl1
gene id: 42514:mettl1
uniprot id: A0A3B4DJ31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with WDR4.
messages: Nucleus

42514:tmtc2b
gene id: 42514:tmtc2b
uniprot id: A0A3B4E755
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

42514:panx1a
gene id: 42514:panx1a
uniprot id: A0A3B4E828
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

42514:LOC108429270
gene id: 42514:LOC108429270
uniprot id: A0A3B4DMV0
names: Similarity
messages: Belongs to the SMEK family.

42514:itpkca
gene id: 42514:itpkca
uniprot id: A0A3B4E4K2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:slc6a15
gene id: 42514:slc6a15
uniprot id: A0A3B4CNG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:cflara
gene id: 42514:cflara
uniprot id: A0A3B4DIF7
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:si:dkey-10o6.2
gene id: 42514:si:dkey-10o6.2
uniprot id: A0A3B4DVH7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

42514:LOC108414284
gene id: 42514:LOC108414284
uniprot id: A0A3B4BJT7
uniprot id: A0A3B4DH14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:ccdc107
gene id: 42514:ccdc107
uniprot id: A0A3B4CKU5
names: Similarity
messages: Belongs to the ric-3 family.

42514:LOC108423775
gene id: 42514:LOC108423775
uniprot id: A0A3B4CRR5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:scamp3
gene id: 42514:scamp3
uniprot id: A0A3B4CHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

42514:ptpn4a
gene id: 42514:ptpn4a
uniprot id: A0A3B4D807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

42514:rpl18
gene id: 42514:rpl18
uniprot id: A0A3B4CQZ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

42514:eif3s10
gene id: 42514:eif3s10
uniprot id: A0A3B4E1V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

42514:tmed9
gene id: 42514:tmed9
uniprot id: A0A3B4D5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:siah1
gene id: 42514:siah1
uniprot id: A0A3B4CDJ2
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

42514:ppa2
gene id: 42514:ppa2
uniprot id: A0A3B4D7R5
names: Similarity
messages: Belongs to the PPase family.

42514:dram1
gene id: 42514:dram1
uniprot id: A0A3B4E5H9
names: Subcellular Location Annotation
messages: Membrane

42514:twf2b
gene id: 42514:twf2b
uniprot id: A0A3B4C599
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

42514:prkceb
gene id: 42514:prkceb
uniprot id: A0A3B4DWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

42514:copg2
gene id: 42514:copg2
uniprot id: A0A3B4DH32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

42514:mrps30
gene id: 42514:mrps30
uniprot id: A0A3B4DHU5
names: Subcellular Location Annotation
messages: Mitochondrion

42514:vim
gene id: 42514:vim
uniprot id: A0A3B4CZH0
names: Function
names: Similarity
messages: Belongs to the intermediate filament family.
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

42514:LOC108444261
gene id: 42514:LOC108444261
uniprot id: A0A3B4DWW4
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

42514:srrd
gene id: 42514:srrd
uniprot id: A0A3B4BQJ6
names: Similarity
messages: Belongs to the SRR1 family.

42514:snd1
gene id: 42514:snd1
uniprot id: A0A3B4DMW7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.

42514:LOC108438266
gene id: 42514:LOC108438266
uniprot id: A0A3B4EK84
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

42514:il17ra1a
gene id: 42514:il17ra1a
uniprot id: A0A3B4BUX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:st3gal2
gene id: 42514:st3gal2
uniprot id: A0A3B4E0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:LOC108415193
gene id: 42514:LOC108415193
uniprot id: A0A3B4CY31
names: Similarity
messages: Belongs to the mTERF family.

42514:LOC108423484
gene id: 42514:LOC108423484
uniprot id: A0A3B4BWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

42514:ppip5k1a
gene id: 42514:ppip5k1a
uniprot id: A0A3B4ECC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

42514:nsfa
gene id: 42514:nsfa
uniprot id: A0A3B4BXM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

42514:plcg1
gene id: 42514:plcg1
uniprot id: A0A3B4D1F4
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

42514:tnfaip6
gene id: 42514:tnfaip6
uniprot id: A0A3B4DZC8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:eif3i
gene id: 42514:eif3i
uniprot id: A0A3B4DDA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

42514:mgat1b
gene id: 42514:mgat1b
uniprot id: A0A3B4D9B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

42514:vasnb
gene id: 42514:vasnb
uniprot id: A0A3B4C5R4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ebf1b
gene id: 42514:ebf1b
uniprot id: A0A3B4C8T1
uniprot id: A0A3B4DTC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

42514:nsrp1
gene id: 42514:nsrp1
uniprot id: A0A3B4C8G5
names: Similarity
messages: Belongs to the NSRP1 family.

42514:maptb
gene id: 42514:maptb
uniprot id: A0A3B4C7C0
uniprot id: A0A3B4C983
uniprot id: A0A3B4CA58
uniprot id: A0A3B4CBE1
uniprot id: A0A3B4DU38
names: Subcellular Location Annotation
messages: cytoskeleton

42514:fgfr1a
gene id: 42514:fgfr1a
uniprot id: A0A3B4E9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

42514:serpind1
gene id: 42514:serpind1
uniprot id: A0A3B4C193
names: Similarity
messages: Belongs to the serpin family.

42514:nagk
gene id: 42514:nagk
uniprot id: A0A3B4DQD0
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

42514:aatf
gene id: 42514:aatf
uniprot id: A0A3B4CBF4
names: Similarity
messages: Belongs to the AATF family.

42514:dolpp1
gene id: 42514:dolpp1
uniprot id: A0A3B4CHA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

42514:LOC108441601
gene id: 42514:LOC108441601
uniprot id: A0A3B4DFT0
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108430143
gene id: 42514:LOC108430143
uniprot id: A0A3B4C902
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:duox
gene id: 42514:duox
uniprot id: A0A3B4CLI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

42514:erlin2
gene id: 42514:erlin2
uniprot id: A0A3B4DHL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

42514:LOC108423685
gene id: 42514:LOC108423685
uniprot id: A0A3B4E2E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL.
messages: Secreted

42514:eml2
gene id: 42514:eml2
uniprot id: A0A3B4BTB5
uniprot id: A0A3B4DJR0
names: Similarity
messages: Belongs to the WD repeat EMAP family.

42514:acat2
gene id: 42514:acat2
uniprot id: A0A3B4ED90
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

42514:spi1b
gene id: 42514:spi1b
uniprot id: A0A3B4E0U4
uniprot id: A0A3B4E277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:slc9a6a
gene id: 42514:slc9a6a
uniprot id: A0A3B4CU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

42514:syt16
gene id: 42514:syt16
uniprot id: A0A3B4CPS5
uniprot id: A0A3B4CS55
names: Similarity
messages: Belongs to the synaptotagmin family.

42514:LOC108430443
gene id: 42514:LOC108430443
uniprot id: A0A3B4EMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:pfkfb3
gene id: 42514:pfkfb3
uniprot id: A0A3B4DGL8
uniprot id: A0A3B4DHR1
uniprot id: A0A3B4EPS3
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

42514:atg101
gene id: 42514:atg101
uniprot id: A0A3B4E0S6
names: Similarity
messages: Belongs to the ATG101 family.

42514:hsdl2
gene id: 42514:hsdl2
uniprot id: A0A3B4CHQ8
names: Subcellular Location Annotation
messages: Peroxisome

42514:tmem30aa
gene id: 42514:tmem30aa
uniprot id: A0A3B4DN51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

42514:ndfip1
gene id: 42514:ndfip1
uniprot id: A0A3B4DQY7
names: Subcellular Location Annotation
messages: Membrane

42514:ppp3ccb
gene id: 42514:ppp3ccb
uniprot id: A0A3B4EF52
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

42514:cdip1
gene id: 42514:cdip1
uniprot id: A0A3B4C5B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

42514:LOC108424007
gene id: 42514:LOC108424007
uniprot id: A0A3B4BZP9
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

42514:rnf157
gene id: 42514:rnf157
uniprot id: A0A3B4BWC9
uniprot id: A0A3B4DPE8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

42514:irx4a
gene id: 42514:irx4a
uniprot id: A0A3B4DVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

42514:hint2
gene id: 42514:hint2
uniprot id: A0A3B4EPE9
names: Similarity
messages: Belongs to the HINT family.

42514:nbr1b
gene id: 42514:nbr1b
uniprot id: A0A3B4CAD6
names: Subcellular Location Annotation
messages: autophagosome

42514:pacsin1b
gene id: 42514:pacsin1b
uniprot id: A0A3B4C490
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

42514:stard9
gene id: 42514:stard9
uniprot id: A0A3B4E2C1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:zgc:109889
gene id: 42514:zgc:109889
uniprot id: A0A3B4C671
uniprot id: A0A3B4DW73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

42514:LOC108415734
gene id: 42514:LOC108415734
uniprot id: A0A3B4EPN3
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

42514:hibadha
gene id: 42514:hibadha
uniprot id: A0A3B4BN20
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

42514:nsmce2
gene id: 42514:nsmce2
uniprot id: A0A3B4D8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

42514:glud1a
gene id: 42514:glud1a
uniprot id: A0A3B4BR48
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

42514:paqr5a
gene id: 42514:paqr5a
uniprot id: A0A3B4CAW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:LOC108432642
gene id: 42514:LOC108432642
uniprot id: A0A3B4DG53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

42514:LOC108431926
gene id: 42514:LOC108431926
uniprot id: A0A3B4C579
uniprot id: A0A3B4C6S7
uniprot id: A0A3B4DR82
uniprot id: A0A3B4DTT7
names: Subcellular Location Annotation
messages: Cytoplasm

42514:sec24a
gene id: 42514:sec24a
uniprot id: A0A3B4E0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:arl4cb
gene id: 42514:arl4cb
uniprot id: A0A3B4DEJ8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

42514:trap1
gene id: 42514:trap1
uniprot id: A0A3B4DT77
names: Similarity
messages: Belongs to the heat shock protein 90 family.

42514:psme3ip1
gene id: 42514:psme3ip1
uniprot id: A0A3B4CFR4
names: Subcellular Location Annotation
messages: Nucleus

42514:smg8
gene id: 42514:smg8
uniprot id: A0A3B4DZC4
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

42514:bora
gene id: 42514:bora
uniprot id: A0A3B4BZJ4
names: Similarity
messages: Belongs to the BORA family.

42514:hnrnpaba
gene id: 42514:hnrnpaba
uniprot id: A0A3B4DJX8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:nme5
gene id: 42514:nme5
uniprot id: A0A3B4DIH6
names: Similarity
messages: Belongs to the NDK family.

42514:ndufb5
gene id: 42514:ndufb5
uniprot id: A0A3B4D927
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

42514:sirt5
gene id: 42514:sirt5
uniprot id: A0A3B4EQ37
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-97 and Arg-100) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
messages: Nucleus
messages: cytosol

42514:fto
gene id: 42514:fto
uniprot id: A0A3B4D4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

42514:gcnt7
gene id: 42514:gcnt7
uniprot id: A0A3B4E1K1
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

42514:si:dkey-239i20.4
gene id: 42514:si:dkey-239i20.4
uniprot id: A0A3B4BRW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

42514:ube2l3a
gene id: 42514:ube2l3a
uniprot id: A0A3B4C5H1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:vsnl1a
gene id: 42514:vsnl1a
uniprot id: A0A3B4BVB8
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

42514:hoxb6a
gene id: 42514:hoxb6a
uniprot id: A0A3B4CDI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:LOC108443715
gene id: 42514:LOC108443715
uniprot id: A0A3B4BUW1
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:LOC108427738
gene id: 42514:LOC108427738
uniprot id: A0A3B4CZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

42514:urm1
gene id: 42514:urm1
uniprot id: A0A3B4CHG2
uniprot id: A0A3B4CKT8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

42514:dync2li1
gene id: 42514:dync2li1
uniprot id: A0A3B4DYW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

42514:tmem150c
gene id: 42514:tmem150c
uniprot id: A0A3B4E2J0
names: Subcellular Location Annotation
messages: Membrane

42514:rock1
gene id: 42514:rock1
uniprot id: A0A3B4D2H3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.

42514:LOC108430080
gene id: 42514:LOC108430080
uniprot id: A0A3B4CHP2
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

42514:rbl2
gene id: 42514:rbl2
uniprot id: A0A3B4DDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

42514:hspa5
gene id: 42514:hspa5
uniprot id: A0A3B4EKE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

42514:sept6
gene id: 42514:sept6
uniprot id: A0A3B4E9B5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

42514:ptpn20
gene id: 42514:ptpn20
uniprot id: A0A3B4DI77
uniprot id: A0A3B4DI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

42514:LOC108424738
gene id: 42514:LOC108424738
uniprot id: A0A3B4DEL2
names: Similarity
messages: Belongs to the heme oxygenase family.

42514:ssr3
gene id: 42514:ssr3
uniprot id: A0A3B4CD80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

42514:LOC108437129
gene id: 42514:LOC108437129
uniprot id: A0A3B4BWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:c2h4orf48
gene id: 42514:c2h4orf48
uniprot id: A0A3B4EAH0
names: Subcellular Location Annotation
messages: Secreted

42514:ano9b
gene id: 42514:ano9b
uniprot id: A0A3B4E0B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

42514:LOC108429428
gene id: 42514:LOC108429428
uniprot id: A0A3B4D8J0
uniprot id: A0A3B4EGK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

42514:abcg8
gene id: 42514:abcg8
uniprot id: A0A3B4C8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

42514:ccdc25
gene id: 42514:ccdc25
uniprot id: A0A3B4BZ23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

42514:LOC108437644
gene id: 42514:LOC108437644
uniprot id: A0A3B4BY08
uniprot id: A0A3B4DND6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

42514:rbp2a
gene id: 42514:rbp2a
uniprot id: A0A3B4CYZ7
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:abitram
gene id: 42514:abitram
uniprot id: A0A3B4DKP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

42514:nxt2
gene id: 42514:nxt2
uniprot id: A0A3B4D7Z1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

42514:oxa1l
gene id: 42514:oxa1l
uniprot id: A0A3B4C5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

42514:alkal1
gene id: 42514:alkal1
uniprot id: A0A3B4E3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

42514:sucla2
gene id: 42514:sucla2
uniprot id: A0A3B4CNT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

42514:nid2a
gene id: 42514:nid2a
uniprot id: A0A3B4C9S8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

42514:waplb
gene id: 42514:waplb
uniprot id: A0A3B4EJ10
names: Similarity
messages: Belongs to the WAPL family.

42514:atg4b
gene id: 42514:atg4b
uniprot id: A0A3B4DCB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: autophagosome
messages: cytosol

42514:notum1a
gene id: 42514:notum1a
uniprot id: A0A3B4D0P4
names: Similarity
messages: Belongs to the pectinacetylesterase family. Notum subfamily.

42514:lta
gene id: 42514:lta
uniprot id: A0A3B4E607
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:mtif3
gene id: 42514:mtif3
uniprot id: A0A3B4EPL0
names: Similarity
messages: Belongs to the IF-3 family.

42514:itpa
gene id: 42514:itpa
uniprot id: A0A3B4BMR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

42514:bpgm
gene id: 42514:bpgm
uniprot id: A0A3B4CUY1
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

42514:LOC108433527
gene id: 42514:LOC108433527
uniprot id: A0A3B4CN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:LOC108424863
gene id: 42514:LOC108424863
uniprot id: A0A3B4EJY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

42514:tgfbr1b
gene id: 42514:tgfbr1b
uniprot id: A0A3B4CTY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:ptpn21
gene id: 42514:ptpn21
uniprot id: A0A3B4BPS6
uniprot id: A0A3B4BSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

42514:frem1b
gene id: 42514:frem1b
uniprot id: A0A3B4EB19
names: Similarity
messages: Belongs to the FRAS1 family.

42514:paqr6
gene id: 42514:paqr6
uniprot id: A0A3B4EMQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:ptpn2b
gene id: 42514:ptpn2b
uniprot id: A0A3B4EJZ5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

42514:micos13
gene id: 42514:micos13
uniprot id: A0A3B4DR31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

42514:yju2
gene id: 42514:yju2
uniprot id: A0A3B4D3W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

42514:gadd45bb
gene id: 42514:gadd45bb
uniprot id: A0A3B4CC44
names: Similarity
messages: Belongs to the GADD45 family.

42514:LOC108428921
gene id: 42514:LOC108428921
uniprot id: A0A3B4EDN7
names: Subcellular Location Annotation
messages: Membrane

42514:cax1
gene id: 42514:cax1
uniprot id: A0A3B4DKQ5
names: Subcellular Location Annotation
messages: Membrane

42514:agtr1a
gene id: 42514:agtr1a
uniprot id: A0A3B4EET5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

42514:abl1
gene id: 42514:abl1
uniprot id: A0A3B4DZQ6
uniprot id: A0A3B4E002
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:tagln2
gene id: 42514:tagln2
uniprot id: A0A3B4C454
names: Similarity
messages: Belongs to the calponin family.

42514:nup107
gene id: 42514:nup107
uniprot id: A0A3B4BX01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

42514:gata6
gene id: 42514:gata6
uniprot id: A0A3B4C4F4
names: Subcellular Location Annotation
messages: Nucleus

42514:chuk
gene id: 42514:chuk
uniprot id: A0A3B4CC00
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:chac1
gene id: 42514:chac1
uniprot id: A0A3B4BZ30
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

42514:mchr1b
gene id: 42514:mchr1b
uniprot id: A0A3B4DKV0
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

42514:gatb
gene id: 42514:gatb
uniprot id: A0A3B4CUN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

42514:myoz3a
gene id: 42514:myoz3a
uniprot id: A0A3B4DNU8
names: Similarity
messages: Belongs to the myozenin family.

42514:cd40lg
gene id: 42514:cd40lg
uniprot id: A0A3B4E616
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:rfc5
gene id: 42514:rfc5
uniprot id: A0A3B4E910
names: Similarity
messages: Belongs to the activator 1 small subunits family.

42514:ppp1r14aa
gene id: 42514:ppp1r14aa
uniprot id: A0A3B4D3U6
names: Similarity
messages: Belongs to the PP1 inhibitor family.

42514:syne3
gene id: 42514:syne3
uniprot id: A0A3B4BTT8
names: Similarity
messages: Belongs to the nesprin family.

42514:lgr4
gene id: 42514:lgr4
uniprot id: A0A3B4CEQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:gsk3bb
gene id: 42514:gsk3bb
uniprot id: A0A3B4CHE6
uniprot id: A0A3B4E3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

42514:LOC108426760
gene id: 42514:LOC108426760
uniprot id: A0A3B4E0P8
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

42514:kif21a
gene id: 42514:kif21a
uniprot id: A0A3B4DHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

42514:hoxb3a
gene id: 42514:hoxb3a
uniprot id: A0A3B4CF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

42514:ufc1
gene id: 42514:ufc1
uniprot id: A0A3B4CDA7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

42514:fzr1b
gene id: 42514:fzr1b
uniprot id: A0A3B4E713
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

42514:slc35b4
gene id: 42514:slc35b4
uniprot id: A0A3B4DGC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

42514:LOC108436601
gene id: 42514:LOC108436601
uniprot id: A0A3B4DA55
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:cd44b
gene id: 42514:cd44b
uniprot id: A0A3B4EPB5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

42514:rin3
gene id: 42514:rin3
uniprot id: A0A3B4D7Y3
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

42514:crtc1b
gene id: 42514:crtc1b
uniprot id: A0A3B4CI37
uniprot id: A0A3B4CIB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108436737
gene id: 42514:LOC108436737
uniprot id: A0A3B4ED85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

42514:hsd17b10
gene id: 42514:hsd17b10
uniprot id: A0A3B4C668
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:ldb2a
gene id: 42514:ldb2a
uniprot id: A0A3B4EMV7
names: Similarity
messages: Belongs to the LDB family.

42514:LOC108434036
gene id: 42514:LOC108434036
uniprot id: A0A3B4E3U2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:slc25a43
gene id: 42514:slc25a43
uniprot id: A0A3B4CNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:tmem98
gene id: 42514:tmem98
uniprot id: A0A3B4DLH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: extracellular exosome

42514:shmt1
gene id: 42514:shmt1
uniprot id: A0A3B4EBK0
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

42514:alcama
gene id: 42514:alcama
uniprot id: A0A3B4E6C4
uniprot id: A0A3B4E7P6
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

42514:LOC108429574
gene id: 42514:LOC108429574
uniprot id: A0A3B4CN12
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:slc29a4
gene id: 42514:slc29a4
uniprot id: A0A3B4D0I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

42514:slc30a1a
gene id: 42514:slc30a1a
uniprot id: A0A3B4DU62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

42514:LOC108433251
gene id: 42514:LOC108433251
uniprot id: A0A3B4EMW6
names: Similarity
messages: Belongs to the peptidase M10A family.

42514:htra3a
gene id: 42514:htra3a
uniprot id: A0A3B4DZD1
names: Similarity
messages: Belongs to the peptidase S1C family.

42514:hpgd
gene id: 42514:hpgd
uniprot id: A0A3B4CPA0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108443108
gene id: 42514:LOC108443108
uniprot id: A0A3B4BYF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:kdm5c
gene id: 42514:kdm5c
uniprot id: A0A3B4BQF1
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

42514:ugp2b
gene id: 42514:ugp2b
uniprot id: A0A3B4D8Q1
uniprot id: A0A3B4EH01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

42514:tpst2
gene id: 42514:tpst2
uniprot id: A0A3B4DN74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

42514:grm3
gene id: 42514:grm3
uniprot id: A0A3B4CX63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

42514:spsb3b
gene id: 42514:spsb3b
uniprot id: A0A3B4E849
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

42514:narf
gene id: 42514:narf
uniprot id: A0A3B4DMA3
names: Similarity
messages: Belongs to the NARF family.

42514:LOC108443171
gene id: 42514:LOC108443171
uniprot id: A0A3B4BWE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

42514:pla2g15
gene id: 42514:pla2g15
uniprot id: A0A3B4DU03
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

42514:chst11
gene id: 42514:chst11
uniprot id: A0A3B4DRH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:tssc4
gene id: 42514:tssc4
uniprot id: A0A3B4CFP4
names: Similarity
messages: Belongs to the TSSC4 family.

42514:mrps10
gene id: 42514:mrps10
uniprot id: A0A3B4CVD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

42514:si:dkeyp-69e1.8
gene id: 42514:si:dkeyp-69e1.8
uniprot id: A0A3B4D3W1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108429431
gene id: 42514:LOC108429431
uniprot id: A0A3B4DWR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: spindle pole

42514:maf1a
gene id: 42514:maf1a
uniprot id: A0A3B4C654
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

42514:trim71
gene id: 42514:trim71
uniprot id: A0A3B4CVE9
names: Similarity
messages: Belongs to the TRIM/RBCC family.

42514:fgf13a
gene id: 42514:fgf13a
uniprot id: A0A3B4CNG8
uniprot id: A0A3B4CS70
uniprot id: A0A3B4E865
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

42514:cited4b
gene id: 42514:cited4b
uniprot id: A0A3B4CBS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

42514:wasf3b
gene id: 42514:wasf3b
uniprot id: A0A3B4EIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

42514:camsap2a
gene id: 42514:camsap2a
uniprot id: A0A3B4CAK4
uniprot id: A0A3B4CCT9
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

42514:bnip3lb
gene id: 42514:bnip3lb
uniprot id: A0A3B4D0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

42514:ywhae2
gene id: 42514:ywhae2
uniprot id: A0A3B4D9K9
uniprot id: A0A3B4DC49
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:gcgb
gene id: 42514:gcgb
uniprot id: A0A3B4EGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

42514:LOC108426109
gene id: 42514:LOC108426109
uniprot id: A0A3B4E0W2
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108438093
gene id: 42514:LOC108438093
uniprot id: A0A3B4BWL0
names: Subcellular Location Annotation
messages: Membrane

42514:twsg1a
gene id: 42514:twsg1a
uniprot id: A0A3B4CDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

42514:ldb3b
gene id: 42514:ldb3b
uniprot id: A0A3B4DNW4
uniprot id: A0A3B4DPU3
names: Subcellular Location Annotation
messages: Z line

42514:adamts8a
gene id: 42514:adamts8a
uniprot id: A0A3B4C272
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:mocs3
gene id: 42514:mocs3
uniprot id: A0A3B4CHE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

42514:fcho2
gene id: 42514:fcho2
uniprot id: A0A3B4CVL2
uniprot id: A0A3B4CXX7
uniprot id: A0A3B4ECS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FCHO family.
messages: clathrin-coated pit

42514:tdrd7b
gene id: 42514:tdrd7b
uniprot id: A0A3B4DPS9
names: Subcellular Location Annotation
messages: Cytoplasm

42514:mxra8b
gene id: 42514:mxra8b
uniprot id: A0A3B4CUB7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:tdrd9
gene id: 42514:tdrd9
uniprot id: A0A3B4DM88
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

42514:minar1
gene id: 42514:minar1
uniprot id: A0A3B4C3Y7
names: Similarity
messages: Belongs to the MINAR family.

42514:wrnip1
gene id: 42514:wrnip1
uniprot id: A0A3B4DU16
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

42514:loxl1
gene id: 42514:loxl1
uniprot id: A0A3B4ERZ0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

42514:exoc3l2b
gene id: 42514:exoc3l2b
uniprot id: A0A3B4BXC5
names: Similarity
messages: Belongs to the SEC6 family.

42514:foxr1
gene id: 42514:foxr1
uniprot id: A0A3B4CH87
names: Subcellular Location Annotation
messages: Nucleus

42514:zgc:114200
gene id: 42514:zgc:114200
uniprot id: A0A3B4EC63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

42514:ctnnbip1
gene id: 42514:ctnnbip1
uniprot id: A0A3B4CV10
names: Similarity
messages: Belongs to the CTNNBIP1 family.

42514:edem3
gene id: 42514:edem3
uniprot id: A0A3B4D446
uniprot id: A0A3B4D5X4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:bri3
gene id: 42514:bri3
uniprot id: A0A3B4CKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

42514:slc6a13
gene id: 42514:slc6a13
uniprot id: A0A3B4EGV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:dact1
gene id: 42514:dact1
uniprot id: A0A3B4DJT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dapper family.
messages: Cytoplasm

42514:clstn3
gene id: 42514:clstn3
uniprot id: A0A3B4E5X9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

42514:lctla
gene id: 42514:lctla
uniprot id: A0A3B4CBA1
uniprot id: A0A3B4E021
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

42514:mnx2b
gene id: 42514:mnx2b
uniprot id: A0A3B4CR76
names: Subcellular Location Annotation
messages: Nucleus

42514:cth1
gene id: 42514:cth1
uniprot id: A0A3B4C8S2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:LOC108443093
gene id: 42514:LOC108443093
uniprot id: A0A3B4DVM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:lamp5
gene id: 42514:lamp5
uniprot id: A0A3B4CSL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

42514:pno1
gene id: 42514:pno1
uniprot id: A0A3B4D2G1
names: Similarity
messages: Belongs to the PNO1 family.

42514:sema4d
gene id: 42514:sema4d
uniprot id: A0A3B4BUU1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:mtx1a
gene id: 42514:mtx1a
uniprot id: A0A3B4DJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:dbx1b
gene id: 42514:dbx1b
uniprot id: A0A3B4D4T9
names: Subcellular Location Annotation
messages: Nucleus

42514:cstf1
gene id: 42514:cstf1
uniprot id: A0A3B4CTW2
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108414085
gene id: 42514:LOC108414085
uniprot id: A0A3B4BNK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:pparab
gene id: 42514:pparab
uniprot id: A0A3B4EIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

42514:LOC108424735
gene id: 42514:LOC108424735
uniprot id: A0A3B4BKF5
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

42514:gadd45ba
gene id: 42514:gadd45ba
uniprot id: A0A3B4EGX0
names: Similarity
messages: Belongs to the GADD45 family.

42514:psenen
gene id: 42514:psenen
uniprot id: A0A3B4C8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane

42514:efnb1
gene id: 42514:efnb1
uniprot id: A0A3B4BM39
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:serpinh1b
gene id: 42514:serpinh1b
uniprot id: A0A3B4E2D6
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

42514:polr2a
gene id: 42514:polr2a
uniprot id: A0A3B4C1X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

42514:tnfsf13b
gene id: 42514:tnfsf13b
uniprot id: A0A3B4DJH1
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:ap2a1
gene id: 42514:ap2a1
uniprot id: A0A3B4CM29
uniprot id: A0A3B4CPB5
uniprot id: A0A3B4E5R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

42514:LOC108432284
gene id: 42514:LOC108432284
uniprot id: A0A3B4E9L8
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homomer. Forms heteromers with ACKR4.
messages: Membrane

42514:LOC108435569
gene id: 42514:LOC108435569
uniprot id: A0A3B4D4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

42514:akirin1
gene id: 42514:akirin1
uniprot id: A0A3B4CQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

42514:mief1
gene id: 42514:mief1
uniprot id: A0A3B4CLR3
uniprot id: A0A3B4CNM1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

42514:napgb
gene id: 42514:napgb
uniprot id: A0A3B4E1F0
names: Similarity
messages: Belongs to the SNAP family.

42514:dbr1
gene id: 42514:dbr1
uniprot id: A0A3B4EI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

42514:exosc9
gene id: 42514:exosc9
uniprot id: A0A3B4BRM8
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108435093
gene id: 42514:LOC108435093
uniprot id: A0A3B4CUX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

42514:gdpd4a
gene id: 42514:gdpd4a
uniprot id: A0A3B4CNT0
uniprot id: A0A3B4E5Y4
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

42514:eva1bb
gene id: 42514:eva1bb
uniprot id: A0A3B4DF16
names: Similarity
messages: Belongs to the EVA1 family.

42514:tshz3b
gene id: 42514:tshz3b
uniprot id: A0A3B4CCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

42514:atat1
gene id: 42514:atat1
uniprot id: A0A3B4D964
uniprot id: A0A3B4D978
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. May be involved in neuron development.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

42514:pfkfb2b
gene id: 42514:pfkfb2b
uniprot id: A0A3B4C5K6
uniprot id: A0A3B4C748
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

42514:zgc:162193
gene id: 42514:zgc:162193
uniprot id: A0A3B4DU05
names: Similarity
messages: Belongs to the TCAF family.

42514:slc6a4a
gene id: 42514:slc6a4a
uniprot id: A0A3B4DM74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:usp37
gene id: 42514:usp37
uniprot id: A0A3B4DWK9
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:crx
gene id: 42514:crx
uniprot id: A0A3B4C397
names: Subcellular Location Annotation
messages: Nucleus

42514:znf830
gene id: 42514:znf830
uniprot id: A0A3B4E3S2
names: Subcellular Location Annotation
messages: Nucleus

42514:gmpr
gene id: 42514:gmpr
uniprot id: A0A3B4BX88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

42514:elf1
gene id: 42514:elf1
uniprot id: A0A3B4CPF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:gabbr2
gene id: 42514:gabbr2
uniprot id: A0A3B4DK01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:brinp3b
gene id: 42514:brinp3b
uniprot id: A0A3B4EIL5
names: Similarity
messages: Belongs to the BRINP family.

42514:lasp1
gene id: 42514:lasp1
uniprot id: A0A3B4DVU7
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

42514:zgc:65851
gene id: 42514:zgc:65851
uniprot id: A0A3B4BPL5
names: Similarity
messages: Belongs to the intermediate filament family.

42514:LOC108431635
gene id: 42514:LOC108431635
uniprot id: A0A3B4D9E6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

42514:LOC108425947
gene id: 42514:LOC108425947
uniprot id: A0A3B4DBK5
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:si:dkeyp-61b2.1
gene id: 42514:si:dkeyp-61b2.1
uniprot id: A0A3B4C835
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zgc:114041
gene id: 42514:zgc:114041
uniprot id: A0A3B4DSX0
names: Subcellular Location Annotation
messages: Membrane

42514:fam98a
gene id: 42514:fam98a
uniprot id: A0A3B4BYH8
names: Similarity
messages: Belongs to the FAM98 family.

42514:pla2g4aa
gene id: 42514:pla2g4aa
uniprot id: A0A3B4CMG8
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

42514:pik3c2b
gene id: 42514:pik3c2b
uniprot id: A0A3B4C417
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

42514:LOC108411997
gene id: 42514:LOC108411997
uniprot id: A0A3B4C0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

42514:apooa
gene id: 42514:apooa
uniprot id: A0A3B4CKA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

42514:pusl1
gene id: 42514:pusl1
uniprot id: A0A3B4D3P8
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

42514:trpv4
gene id: 42514:trpv4
uniprot id: A0A3B4BRR7
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108435609
gene id: 42514:LOC108435609
uniprot id: A0A3B4D1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

42514:l1cama
gene id: 42514:l1cama
uniprot id: A0A3B4CXD3
uniprot id: A0A3B4D1M0
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

42514:arpp19a
gene id: 42514:arpp19a
uniprot id: A0A3B4D403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

42514:sec61a1l
gene id: 42514:sec61a1l
uniprot id: A0A3B4CEH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:gpc6a
gene id: 42514:gpc6a
uniprot id: A0A3B4BNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

42514:slc25a46
gene id: 42514:slc25a46
uniprot id: A0A3B4BL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:mrps21
gene id: 42514:mrps21
uniprot id: A0A3B4CJ68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

42514:ppm1la
gene id: 42514:ppm1la
uniprot id: A0A3B4CP32
names: Similarity
messages: Belongs to the PP2C family.

42514:mid1
gene id: 42514:mid1
uniprot id: A0A3B4D7H1
uniprot id: A0A3B4EJR9
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

42514:LOC108442004
gene id: 42514:LOC108442004
uniprot id: A0A3B4BVU8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:pkp4
gene id: 42514:pkp4
uniprot id: A0A3B4D1P1
names: Similarity
messages: Belongs to the beta-catenin family.

42514:im:7151449
gene id: 42514:im:7151449
uniprot id: A0A3B4BZI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:thumpd2
gene id: 42514:thumpd2
uniprot id: A0A3B4EC68
names: Similarity
messages: Belongs to the methyltransferase superfamily.

42514:dcp2
gene id: 42514:dcp2
uniprot id: A0A3B4CSC6
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

42514:xkr5a
gene id: 42514:xkr5a
uniprot id: A0A3B4C6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:csnk1g1
gene id: 42514:csnk1g1
uniprot id: A0A3B4EBV0
uniprot id: A0A3B4ECZ4
uniprot id: A0A3B4ED24
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

42514:kcnj6
gene id: 42514:kcnj6
uniprot id: A0A3B4CP65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

42514:tmem121ab
gene id: 42514:tmem121ab
uniprot id: A0A3B4C3Q2
names: Similarity
messages: Belongs to the TMEM121 family.

42514:cnih3
gene id: 42514:cnih3
uniprot id: A0A3B4CBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

42514:pipox
gene id: 42514:pipox
uniprot id: A0A3B4BUP6
uniprot id: A0A3B4BY04
names: Similarity
messages: Belongs to the MSOX/MTOX family.

42514:ano5a
gene id: 42514:ano5a
uniprot id: A0A3B4BQ79
uniprot id: A0A3B4BQG1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:prkab2
gene id: 42514:prkab2
uniprot id: A0A3B4C4J4
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

42514:kcnk5a
gene id: 42514:kcnk5a
uniprot id: A0A3B4DTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:LOC108410933
gene id: 42514:LOC108410933
uniprot id: A0A3B4ELI6
names: Subcellular Location Annotation
messages: Nucleus

42514:cavin4b
gene id: 42514:cavin4b
uniprot id: A0A3B4C577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

42514:tgfb1b
gene id: 42514:tgfb1b
uniprot id: A0A3B4CKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

42514:rad51d
gene id: 42514:rad51d
uniprot id: A0A3B4CJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
messages: Nucleus

42514:slc16a13
gene id: 42514:slc16a13
uniprot id: A0A3B4D8U8
names: Subcellular Location Annotation
messages: Membrane

42514:rab32a
gene id: 42514:rab32a
uniprot id: A0A3B4DND7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

42514:si:ch73-362m14.4
gene id: 42514:si:ch73-362m14.4
uniprot id: A0A3B4D4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

42514:manbal
gene id: 42514:manbal
uniprot id: A0A3B4D8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

42514:etv1
gene id: 42514:etv1
uniprot id: A0A3B4BRS1
uniprot id: A0A3B4BV56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:pcmtl
gene id: 42514:pcmtl
uniprot id: A0A3B4CQG4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

42514:gria2b
gene id: 42514:gria2b
uniprot id: A0A3B4CDY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:gjd1a
gene id: 42514:gjd1a
uniprot id: A0A3B4C684
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:capza1a
gene id: 42514:capza1a
uniprot id: A0A3B4BY77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

42514:prrx1a
gene id: 42514:prrx1a
uniprot id: A0A3B4DF65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

42514:agxt2
gene id: 42514:agxt2
uniprot id: A0A3B4ECH3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

42514:ntrk3a
gene id: 42514:ntrk3a
uniprot id: A0A3B4CJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:ywhah
gene id: 42514:ywhah
uniprot id: A0A3B4CXZ8
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:tes
gene id: 42514:tes
uniprot id: A0A3B4ELB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

42514:slc12a5a
gene id: 42514:slc12a5a
uniprot id: A0A3B4D9G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:amotl2a
gene id: 42514:amotl2a
uniprot id: A0A3B4DE42
names: Similarity
messages: Belongs to the angiomotin family.

42514:tmem106ba
gene id: 42514:tmem106ba
uniprot id: A0A3B4BRG6
names: Similarity
messages: Belongs to the TMEM106 family.

42514:itm2cb
gene id: 42514:itm2cb
uniprot id: A0A3B4DDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

42514:naa30
gene id: 42514:naa30
uniprot id: A0A3B4E4H6
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

42514:slc31a1
gene id: 42514:slc31a1
uniprot id: A0A3B4BSF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

42514:LOC108412930
gene id: 42514:LOC108412930
uniprot id: A0A3B4CH64
uniprot id: A0A3B4DYR4
names: Similarity
messages: Belongs to the MHC class I family.

42514:gpr161a
gene id: 42514:gpr161a
uniprot id: A0A3B4D225
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:st18
gene id: 42514:st18
uniprot id: A0A3B4CJB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

42514:pthlha
gene id: 42514:pthlha
uniprot id: A0A3B4BSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

42514:hspb15
gene id: 42514:hspb15
uniprot id: A0A3B4D074
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:fgf12a
gene id: 42514:fgf12a
uniprot id: A0A3B4DEU7
uniprot id: A0A3B4DFA5
uniprot id: A0A3B4EPM6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:LOC108434067
gene id: 42514:LOC108434067
uniprot id: A0A3B4CF08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:csnk2b
gene id: 42514:csnk2b
uniprot id: A0A3B4DAJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

42514:si:ch211-127i16.2
gene id: 42514:si:ch211-127i16.2
uniprot id: A0A3B4CLV8
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

42514:rragca
gene id: 42514:rragca
uniprot id: A0A3B4C3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

42514:sys1
gene id: 42514:sys1
uniprot id: A0A3B4C566
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

42514:LOC108439431
gene id: 42514:LOC108439431
uniprot id: A0A3B4EEH8
names: Similarity
messages: Belongs to the multicopper oxidase family.

42514:scfd2
gene id: 42514:scfd2
uniprot id: A0A3B4BV02
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

42514:cd79b
gene id: 42514:cd79b
uniprot id: A0A3B4EIX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:ildr1b
gene id: 42514:ildr1b
uniprot id: A0A3B4D2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

42514:dennd6aa
gene id: 42514:dennd6aa
uniprot id: A0A3B4ELC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

42514:parvg
gene id: 42514:parvg
uniprot id: A0A3B4DEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

42514:LOC108412776
gene id: 42514:LOC108412776
uniprot id: A0A3B4CYU3
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

42514:rpain
gene id: 42514:rpain
uniprot id: A0A3B4BUE4
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108442698
gene id: 42514:LOC108442698
uniprot id: A0A3B4BQ62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:atm
gene id: 42514:atm
uniprot id: A0A3B4C7R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: Nucleus

42514:prdm13
gene id: 42514:prdm13
uniprot id: A0A3B4BJY1
names: Subcellular Location Annotation
messages: Nucleus

42514:ldhba
gene id: 42514:ldhba
uniprot id: A0A3B4CGP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

42514:vipr2
gene id: 42514:vipr2
uniprot id: A0A3B4DES2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

42514:stat4
gene id: 42514:stat4
uniprot id: A0A3B4CU36
uniprot id: A0A3B4CU51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

42514:tsen34
gene id: 42514:tsen34
uniprot id: A0A3B4DEW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

42514:mif
gene id: 42514:mif
uniprot id: A0A3B4DA24
names: Similarity
messages: Belongs to the MIF family.

42514:LOC108431120
gene id: 42514:LOC108431120
uniprot id: A0A3B4EH89
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:LOC108434137
gene id: 42514:LOC108434137
uniprot id: A0A3B4DVN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:zgc:110366
gene id: 42514:zgc:110366
uniprot id: A0A3B4E5J1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

42514:polr2i
gene id: 42514:polr2i
uniprot id: A0A3B4EJP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

42514:LOC108428088
gene id: 42514:LOC108428088
uniprot id: A0A3B4C3J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine gamma family.
messages: Secreted

42514:LOC108413708
gene id: 42514:LOC108413708
uniprot id: A0A3B4DSW2
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:LOC108415529
gene id: 42514:LOC108415529
uniprot id: A0A3B4C711
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

42514:LOC108412782
gene id: 42514:LOC108412782
uniprot id: A0A3B4EC28
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

42514:LOC108415693
gene id: 42514:LOC108415693
uniprot id: A0A3B4EM49
names: Similarity
messages: Belongs to the cystatin family.

42514:pbx3a
gene id: 42514:pbx3a
uniprot id: A0A3B4CWP9
uniprot id: A0A3B4CY91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

42514:skap2
gene id: 42514:skap2
uniprot id: A0A3B4BSB1
names: Similarity
messages: Belongs to the SKAP family.

42514:cpeb3
gene id: 42514:cpeb3
uniprot id: A0A3B4C4J9
uniprot id: A0A3B4DTF4
names: Similarity
messages: Belongs to the RRM CPEB family.

42514:zufsp
gene id: 42514:zufsp
uniprot id: A0A3B4DWC5
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

42514:LOC108431405
gene id: 42514:LOC108431405
uniprot id: A0A3B4C1H1
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:oxsm
gene id: 42514:oxsm
uniprot id: A0A3B4E474
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

42514:rgs14a
gene id: 42514:rgs14a
uniprot id: A0A3B4BVP0
uniprot id: A0A3B4BYT9
names: Subcellular Location Annotation
messages: dendrite

42514:txlng
gene id: 42514:txlng
uniprot id: A0A3B4C5V7
names: Similarity
messages: Belongs to the taxilin family.

42514:vegfab
gene id: 42514:vegfab
uniprot id: A0A3B4CR50
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:rdh12l
gene id: 42514:rdh12l
uniprot id: A0A3B4EDR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:gpr37b
gene id: 42514:gpr37b
uniprot id: A0A3B4D8C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:ap4b1
gene id: 42514:ap4b1
uniprot id: A0A3B4CXI3
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

42514:gli3
gene id: 42514:gli3
uniprot id: A0A3B4DWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

42514:si:ch211-13f8.2
gene id: 42514:si:ch211-13f8.2
uniprot id: A0A3B4CLE4
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

42514:acss2l
gene id: 42514:acss2l
uniprot id: A0A3B4E041
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:dpep2
gene id: 42514:dpep2
uniprot id: A0A3B4D5H4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

42514:f8
gene id: 42514:f8
uniprot id: A0A3B4D0Q0
names: Similarity
messages: Belongs to the multicopper oxidase family.

42514:abr
gene id: 42514:abr
uniprot id: A0A3B4E3X2
uniprot id: A0A3B4E443
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

42514:b3galt6
gene id: 42514:b3galt6
uniprot id: A0A3B4C488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:pigg
gene id: 42514:pigg
uniprot id: A0A3B4D3P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:slc24a4b
gene id: 42514:slc24a4b
uniprot id: A0A3B4DTG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

42514:si:ch211-232m10.6
gene id: 42514:si:ch211-232m10.6
uniprot id: A0A3B4D7L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

42514:ephb2b
gene id: 42514:ephb2b
uniprot id: A0A3B4CSV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:mrs2
gene id: 42514:mrs2
uniprot id: A0A3B4CWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

42514:serbp1a
gene id: 42514:serbp1a
uniprot id: A0A3B4DQZ4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:LOC108438821
gene id: 42514:LOC108438821
uniprot id: A0A3B4DBD3
names: Subcellular Location Annotation
messages: Nucleus

42514:oprk1
gene id: 42514:oprk1
uniprot id: A0A3B4E712
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:ndst3
gene id: 42514:ndst3
uniprot id: A0A3B4DU07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

42514:s1pr2
gene id: 42514:s1pr2
uniprot id: A0A3B4CL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:LOC108437208
gene id: 42514:LOC108437208
uniprot id: A0A3B4DBS0
names: Subcellular Location Annotation
messages: ruffle membrane

42514:nipa2
gene id: 42514:nipa2
uniprot id: A0A3B4C6B0
uniprot id: A0A3B4DVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

42514:acad9
gene id: 42514:acad9
uniprot id: A0A3B4DHE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

42514:kcnh5a
gene id: 42514:kcnh5a
uniprot id: A0A3B4D8P3
names: Subcellular Location Annotation
messages: Membrane

42514:slc24a6a
gene id: 42514:slc24a6a
uniprot id: A0A3B4E7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

42514:LOC108443772
gene id: 42514:LOC108443772
uniprot id: A0A3B4DGH4
uniprot id: A0A3B4DGJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus
messages: telomere

42514:suox
gene id: 42514:suox
uniprot id: A0A3B4BUQ2
names: Function
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.

42514:inpp4ab
gene id: 42514:inpp4ab
uniprot id: A0A3B4CUG7
uniprot id: A0A3B4EAR1
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

42514:taar11
gene id: 42514:taar11
uniprot id: A0A3B4CXS8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108410457
gene id: 42514:LOC108410457
uniprot id: A0A3B4D2D0
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:LOC108439020
gene id: 42514:LOC108439020
uniprot id: A0A3B4CLA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

42514:bcl9l
gene id: 42514:bcl9l
uniprot id: A0A3B4C7M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

42514:dlgap4b
gene id: 42514:dlgap4b
uniprot id: A0A3B4DDD6
uniprot id: A0A3B4EPA2
names: Similarity
messages: Belongs to the SAPAP family.

42514:epg5
gene id: 42514:epg5
uniprot id: A0A3B4DRN4
names: Similarity
messages: Belongs to the EPG5 family.

42514:plk1
gene id: 42514:plk1
uniprot id: A0A3B4DWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Midbody
messages: Nucleus
messages: centrosome

42514:emc9
gene id: 42514:emc9
uniprot id: A0A3B4C0R7
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

42514:tet3
gene id: 42514:tet3
uniprot id: A0A3B4EKG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

42514:shq1
gene id: 42514:shq1
uniprot id: A0A3B4EKD2
names: Similarity
messages: Belongs to the SHQ1 family.

42514:lss
gene id: 42514:lss
uniprot id: A0A3B4C601
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

42514:gmnn
gene id: 42514:gmnn
uniprot id: A0A3B4BYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

42514:chd3
gene id: 42514:chd3
uniprot id: A0A3B4CSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

42514:lck
gene id: 42514:lck
uniprot id: A0A3B4EHU7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:LOC108425194
gene id: 42514:LOC108425194
uniprot id: A0A3B4CAA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

42514:vamp3
gene id: 42514:vamp3
uniprot id: A0A3B4C4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

42514:LOC108427751
gene id: 42514:LOC108427751
uniprot id: A0A3B4D2X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

42514:LOC108411280
gene id: 42514:LOC108411280
uniprot id: A0A3B4ED09
names: Similarity
messages: Belongs to the fl(2)d family.

42514:LOC108436944
gene id: 42514:LOC108436944
uniprot id: A0A3B4DZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:hspa14
gene id: 42514:hspa14
uniprot id: A0A3B4DNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

42514:msh3
gene id: 42514:msh3
uniprot id: A0A3B4DF10
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

42514:egfra
gene id: 42514:egfra
uniprot id: A0A3B4DUA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

42514:lrrc8aa
gene id: 42514:lrrc8aa
uniprot id: A0A3B4CZ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

42514:LOC108437939
gene id: 42514:LOC108437939
uniprot id: A0A3B4CHG1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

42514:anapc10
gene id: 42514:anapc10
uniprot id: A0A3B4BRM7
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

42514:opa3
gene id: 42514:opa3
uniprot id: A0A3B4EQC1
names: Function
names: Similarity
messages: Belongs to the OPA3 family.
messages: May play some role in mitochondrial processes.

42514:fam207a
gene id: 42514:fam207a
uniprot id: A0A3B4CWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

42514:ppp4cb
gene id: 42514:ppp4cb
uniprot id: A0A3B4EFS5
names: Similarity
messages: Belongs to the PPP phosphatase family.

42514:pes
gene id: 42514:pes
uniprot id: A0A3B4EBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

42514:atp1b2b
gene id: 42514:atp1b2b
uniprot id: A0A3B4CAK9
uniprot id: A0A3B4DYZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

42514:erc1a
gene id: 42514:erc1a
uniprot id: A0A3B4CJ04
uniprot id: A0A3B4CKW7
uniprot id: A0A3B4E6A1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108443084
gene id: 42514:LOC108443084
uniprot id: A0A3B4DWG8
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:mfsd3
gene id: 42514:mfsd3
uniprot id: A0A3B4BWF8
names: Subcellular Location Annotation
messages: Membrane

42514:hoxa3a
gene id: 42514:hoxa3a
uniprot id: A0A3B4BNE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

42514:LOC108428495
gene id: 42514:LOC108428495
uniprot id: A0A3B4C8R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Cell membrane
messages: Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill.
messages: Membrane

42514:tgfbr2l
gene id: 42514:tgfbr2l
uniprot id: A0A3B4DX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

42514:LOC108441939
gene id: 42514:LOC108441939
uniprot id: A0A3B4DTH0
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

42514:fam49bb
gene id: 42514:fam49bb
uniprot id: A0A3B4DNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

42514:kcnn4
gene id: 42514:kcnn4
uniprot id: A0A3B4EI48
names: Subcellular Location Annotation
messages: Membrane

42514:prkcea
gene id: 42514:prkcea
uniprot id: A0A3B4DPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

42514:LOC108411438
gene id: 42514:LOC108411438
uniprot id: A0A3B4EMR1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:hhatla
gene id: 42514:hhatla
uniprot id: A0A3B4ELW2
names: Subcellular Location Annotation
messages: Membrane

42514:cpsf3
gene id: 42514:cpsf3
uniprot id: A0A3B4EFC8
names: Subcellular Location Annotation
messages: Nucleus

42514:ccnb2
gene id: 42514:ccnb2
uniprot id: A0A3B4CT40
names: Similarity
messages: Belongs to the cyclin family.

42514:st14b
gene id: 42514:st14b
uniprot id: A0A3B4CI85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Degrades extracellular matrix.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:ano8b
gene id: 42514:ano8b
uniprot id: A0A3B4DRV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108442155
gene id: 42514:LOC108442155
uniprot id: A0A3B4DIH8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:zdhhc14
gene id: 42514:zdhhc14
uniprot id: A0A3B4D574
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:gpx8
gene id: 42514:gpx8
uniprot id: A0A3B4CTK9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

42514:pdyn
gene id: 42514:pdyn
uniprot id: A0A3B4CWC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

42514:efna5a
gene id: 42514:efna5a
uniprot id: A0A3B4CHE9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:si:dkey-190g6.2
gene id: 42514:si:dkey-190g6.2
uniprot id: A0A3B4CY59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

42514:hyou1
gene id: 42514:hyou1
uniprot id: A0A3B4DL52
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:aurkb
gene id: 42514:aurkb
uniprot id: A0A3B4C7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: Chromosome

42514:ppp2r2bb
gene id: 42514:ppp2r2bb
uniprot id: A0A3B4DAY7
uniprot id: A0A3B4DCL0
uniprot id: A0A3B4DCL6
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

42514:LOC108441254
gene id: 42514:LOC108441254
uniprot id: A0A3B4CNM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
messages: Belongs to the actin family. ARP2 subfamily.
messages: Component of the Arp2/3 complex.
messages: cytoskeleton

42514:rbm47
gene id: 42514:rbm47
uniprot id: A0A3B4BR56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Nucleus

42514:rps20
gene id: 42514:rps20
uniprot id: A0A3B4EAE5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

42514:palm1a
gene id: 42514:palm1a
uniprot id: A0A3B4D401
uniprot id: A0A3B4D515
uniprot id: A0A3B4EGU4
names: Similarity
messages: Belongs to the paralemmin family.

42514:LOC108443860
gene id: 42514:LOC108443860
uniprot id: A0A3B4BPV5
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

42514:ndufb2
gene id: 42514:ndufb2
uniprot id: A0A3B4BXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

42514:gnpda2
gene id: 42514:gnpda2
uniprot id: A0A3B4D641
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

42514:dcaf13
gene id: 42514:dcaf13
uniprot id: A0A3B4DPV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

42514:mtmr4
gene id: 42514:mtmr4
uniprot id: A0A3B4CPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

42514:myf6
gene id: 42514:myf6
uniprot id: A0A3B4DRZ6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

42514:kat7a
gene id: 42514:kat7a
uniprot id: A0A3B4C8X0
uniprot id: A0A3B4CCE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

42514:ik
gene id: 42514:ik
uniprot id: A0A3B4CSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

42514:alg9
gene id: 42514:alg9
uniprot id: A0A3B4CBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:lmnl3
gene id: 42514:lmnl3
uniprot id: A0A3B4CH96
uniprot id: A0A3B4E0T1
names: Similarity
messages: Belongs to the intermediate filament family.

42514:lmnb2
gene id: 42514:lmnb2
uniprot id: A0A3B4EED5
names: Similarity
messages: Belongs to the intermediate filament family.

42514:ppil2
gene id: 42514:ppil2
uniprot id: A0A3B4E9Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
messages: Nucleus

42514:snrpg
gene id: 42514:snrpg
uniprot id: A0A3B4CY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

42514:zgc:77849
gene id: 42514:zgc:77849
uniprot id: A0A3B4DWU8
names: Similarity
messages: Belongs to the TAPR1 family.

42514:chpfb
gene id: 42514:chpfb
uniprot id: A0A3B4EBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

42514:glyctk
gene id: 42514:glyctk
uniprot id: A0A3B4BRN5
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

42514:LOC108415657
gene id: 42514:LOC108415657
uniprot id: A0A3B4BX26
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108428931
gene id: 42514:LOC108428931
uniprot id: A0A3B4CVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

42514:LOC108437555
gene id: 42514:LOC108437555
uniprot id: A0A3B4CAF9
names: Similarity
messages: Belongs to the peptidase S9A family.

42514:dlgap1a
gene id: 42514:dlgap1a
uniprot id: A0A3B4CQ67
uniprot id: A0A3B4E7Q9
names: Similarity
messages: Belongs to the SAPAP family.

42514:hoxa2b
gene id: 42514:hoxa2b
uniprot id: A0A3B4DLV6
names: Subcellular Location Annotation
messages: Nucleus

42514:map4l
gene id: 42514:map4l
uniprot id: A0A3B4BS55
uniprot id: A0A3B4BVF0
names: Subcellular Location Annotation
messages: cytoskeleton

42514:zdhhc24
gene id: 42514:zdhhc24
uniprot id: A0A3B4E7K9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:fermt3b
gene id: 42514:fermt3b
uniprot id: A0A3B4BR39
names: Similarity
messages: Belongs to the kindlin family.

42514:s100a10a
gene id: 42514:s100a10a
uniprot id: A0A3B4CK86
names: Function
names: Similarity
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.
messages: Belongs to the S-100 family.

42514:ccr7
gene id: 42514:ccr7
uniprot id: A0A3B4C974
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

42514:pygl
gene id: 42514:pygl
uniprot id: A0A3B4C7E7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

42514:mapre1a
gene id: 42514:mapre1a
uniprot id: A0A3B4CJB7
uniprot id: A0A3B4E165
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: centrosome
messages: spindle pole

42514:atp7a
gene id: 42514:atp7a
uniprot id: A0A3B4EEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

42514:limd1a
gene id: 42514:limd1a
uniprot id: A0A3B4CUH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zyxin/ajuba family.
messages: Cytoplasm
messages: Nucleus

42514:bmp10
gene id: 42514:bmp10
uniprot id: A0A3B4BPK1
names: Similarity
messages: Belongs to the TGF-beta family.

42514:fbp1b
gene id: 42514:fbp1b
uniprot id: A0A3B4CTT9
names: Similarity
messages: Belongs to the FBPase class 1 family.

42514:runx3
gene id: 42514:runx3
uniprot id: A0A3B4CFK1
names: Subcellular Location Annotation
messages: Nucleus

42514:fzd3a
gene id: 42514:fzd3a
uniprot id: A0A3B4DMF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:slc35a4
gene id: 42514:slc35a4
uniprot id: A0A3B4DRZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

42514:nptx2a
gene id: 42514:nptx2a
uniprot id: A0A3B4CIZ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:adra2b
gene id: 42514:adra2b
uniprot id: A0A3B4E845
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:galnt2
gene id: 42514:galnt2
uniprot id: A0A3B4CDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:pclaf
gene id: 42514:pclaf
uniprot id: A0A3B4E1T0
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

42514:fam72a
gene id: 42514:fam72a
uniprot id: A0A3B4C2I7
names: Similarity
messages: Belongs to the FAM72 family.

42514:si:ch211-191a24.4
gene id: 42514:si:ch211-191a24.4
uniprot id: A0A3B4DAX9
names: Subcellular Location Annotation
messages: Membrane

42514:fgf20b
gene id: 42514:fgf20b
uniprot id: A0A3B4E7J9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:grm2a
gene id: 42514:grm2a
uniprot id: A0A3B4E384
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

42514:xkr6b
gene id: 42514:xkr6b
uniprot id: A0A3B4D9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:zgc:109965
gene id: 42514:zgc:109965
uniprot id: A0A3B4D6T5
names: Function
names: Similarity
messages: Belongs to the nicastrin family.
messages: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

42514:rad17
gene id: 42514:rad17
uniprot id: A0A3B4D1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

42514:LOC108427313
gene id: 42514:LOC108427313
uniprot id: A0A3B4E560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

42514:LOC108430306
gene id: 42514:LOC108430306
uniprot id: A0A3B4DJ88
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

42514:gpr158a
gene id: 42514:gpr158a
uniprot id: A0A3B4DD23
uniprot id: A0A3B4DFQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

42514:ube2kb
gene id: 42514:ube2kb
uniprot id: A0A3B4D8A4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:prpf4ba
gene id: 42514:prpf4ba
uniprot id: A0A3B4DKM2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

42514:maco1b
gene id: 42514:maco1b
uniprot id: A0A3B4CEL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

42514:tent5aa
gene id: 42514:tent5aa
uniprot id: A0A3B4BY14
names: Similarity
messages: Belongs to the TENT family.

42514:etfa
gene id: 42514:etfa
uniprot id: A0A3B4C9V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

42514:coro2ba
gene id: 42514:coro2ba
uniprot id: A0A3B4CD18
uniprot id: A0A3B4CEU1
uniprot id: A0A3B4E031
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:zgc:112962
gene id: 42514:zgc:112962
uniprot id: A0A3B4DAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOR1AIP family.
messages: Membrane

42514:LOC108423446
gene id: 42514:LOC108423446
uniprot id: A0A3B4C4U3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:osbpl2b
gene id: 42514:osbpl2b
uniprot id: A0A3B4BUX8
names: Similarity
messages: Belongs to the OSBP family.

42514:adka
gene id: 42514:adka
uniprot id: A0A3B4CB61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

42514:arrdc1a
gene id: 42514:arrdc1a
uniprot id: A0A3B4CUU8
names: Similarity
messages: Belongs to the arrestin family.

42514:LOC108433586
gene id: 42514:LOC108433586
uniprot id: A0A3B4E129
names: Similarity
messages: Belongs to the ZC3H12 family.

42514:cpne2
gene id: 42514:cpne2
uniprot id: A0A3B4CHL0
names: Similarity
messages: Belongs to the copine family.

42514:mospd1
gene id: 42514:mospd1
uniprot id: A0A3B4E979
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

42514:gal3st1a
gene id: 42514:gal3st1a
uniprot id: A0A3B4CVK9
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

42514:aasdhppt
gene id: 42514:aasdhppt
uniprot id: A0A3B4EDR7
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

42514:gpr39
gene id: 42514:gpr39
uniprot id: A0A3B4D3S0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:inhbb
gene id: 42514:inhbb
uniprot id: A0A3B4CK11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

42514:th2
gene id: 42514:th2
uniprot id: A0A3B4CEE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

42514:LOC108439566
gene id: 42514:LOC108439566
uniprot id: A0A3B4E8U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

42514:prdm8
gene id: 42514:prdm8
uniprot id: A0A3B4BLK6
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108424624
gene id: 42514:LOC108424624
uniprot id: A0A3B4DIB7
names: Subcellular Location Annotation
messages: Nucleus

42514:irf1a
gene id: 42514:irf1a
uniprot id: A0A3B4E083
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:pcsk5b
gene id: 42514:pcsk5b
uniprot id: A0A3B4CKH8
names: Similarity
messages: Belongs to the peptidase S8 family.

42514:rab14l
gene id: 42514:rab14l
uniprot id: A0A3B4CBT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

42514:LOC108411142
gene id: 42514:LOC108411142
uniprot id: A0A3B4CFW1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:hcrtr2
gene id: 42514:hcrtr2
uniprot id: A0A3B4D3C3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:anapc4
gene id: 42514:anapc4
uniprot id: A0A3B4BZN6
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

42514:usp30
gene id: 42514:usp30
uniprot id: A0A3B4BVN4
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:man1b1b
gene id: 42514:man1b1b
uniprot id: A0A3B4EB63
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:epb41l5
gene id: 42514:epb41l5
uniprot id: A0A3B4EIZ0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

42514:hoxa13b
gene id: 42514:hoxa13b
uniprot id: A0A3B4BSN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:ldha
gene id: 42514:ldha
uniprot id: A0A3B4DZN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Cytoplasm
messages: Homotetramer.

42514:ap4s1
gene id: 42514:ap4s1
uniprot id: A0A3B4CQT7
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

42514:LOC108411383
gene id: 42514:LOC108411383
uniprot id: A0A3B4BLX1
uniprot id: A0A3B4DJ96
names: Similarity
messages: Belongs to the TAFA family.

42514:sec16a
gene id: 42514:sec16a
uniprot id: A0A3B4CLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

42514:eif1
gene id: 42514:eif1
uniprot id: A0A3B4CW57
names: Similarity
messages: Belongs to the SUI1 family.

42514:si:ch211-283g2.1
gene id: 42514:si:ch211-283g2.1
uniprot id: A0A3B4BUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:LOC108437279
gene id: 42514:LOC108437279
uniprot id: A0A3B4D3M5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:anxa1a
gene id: 42514:anxa1a
uniprot id: A0A3B4BT83
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Cytoplasm
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium

42514:si:ch211-243g18.2
gene id: 42514:si:ch211-243g18.2
uniprot id: A0A3B4CIN1
names: Similarity
messages: Belongs to the intermediate filament family.

42514:med19a
gene id: 42514:med19a
uniprot id: A0A3B4D7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:sfrp5
gene id: 42514:sfrp5
uniprot id: A0A3B4DHV7
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:impa1
gene id: 42514:impa1
uniprot id: A0A3B4ELX4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

42514:LOC108412145
gene id: 42514:LOC108412145
uniprot id: A0A3B4EA74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:kmt2a
gene id: 42514:kmt2a
uniprot id: A0A3B4EEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
messages: Nucleus

42514:LOC108417294
gene id: 42514:LOC108417294
uniprot id: A0A3B4D709
names: Similarity
messages: Belongs to the IAP family.

42514:clic5a
gene id: 42514:clic5a
uniprot id: A0A3B4E973
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

42514:gab2
gene id: 42514:gab2
uniprot id: A0A3B4DS66
names: Similarity
messages: Belongs to the GAB family.

42514:tekt3
gene id: 42514:tekt3
uniprot id: A0A3B4C321
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

42514:LOC108424756
gene id: 42514:LOC108424756
uniprot id: A0A3B4DGE7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108424631
gene id: 42514:LOC108424631
uniprot id: A0A3B4BQP0
uniprot id: A0A3B4DI97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Heterodimer; with an rxr molecule. Binds DNA preferentially as a rar/rxr heterodimer.
messages: Nucleus

42514:LOC108435090
gene id: 42514:LOC108435090
uniprot id: A0A3B4CXD1
uniprot id: A0A3B4CY40
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

42514:tspan12
gene id: 42514:tspan12
uniprot id: A0A3B4DQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:slc2a9l2
gene id: 42514:slc2a9l2
uniprot id: A0A3B4C7S7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:prrx1b
gene id: 42514:prrx1b
uniprot id: A0A3B4ENB1
names: Subcellular Location Annotation
messages: Nucleus

42514:ptx3a
gene id: 42514:ptx3a
uniprot id: A0A3B4C968
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:six2b
gene id: 42514:six2b
uniprot id: A0A3B4BXT2
names: Subcellular Location Annotation
messages: Nucleus

42514:tshz3a
gene id: 42514:tshz3a
uniprot id: A0A3B4CNV8
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

42514:fam131c
gene id: 42514:fam131c
uniprot id: A0A3B4E9X4
names: Similarity
messages: Belongs to the FAM131 family.

42514:mtch2
gene id: 42514:mtch2
uniprot id: A0A3B4D1E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:slc15a4
gene id: 42514:slc15a4
uniprot id: A0A3B4C819
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

42514:si:dkeyp-41f9.4
gene id: 42514:si:dkeyp-41f9.4
uniprot id: A0A3B4E2I5
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108411755
gene id: 42514:LOC108411755
uniprot id: A0A3B4E6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

42514:zic6
gene id: 42514:zic6
uniprot id: A0A3B4CS83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

42514:zic4
gene id: 42514:zic4
uniprot id: A0A3B4DGP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

42514:dvl3a
gene id: 42514:dvl3a
uniprot id: A0A3B4E4L3
names: Similarity
messages: Belongs to the DSH family.

42514:nppa
gene id: 42514:nppa
uniprot id: A0A3B4DAD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

42514:cygb2
gene id: 42514:cygb2
uniprot id: A0A3B4EPL8
names: Similarity
messages: Belongs to the globin family.

42514:ap1s2
gene id: 42514:ap1s2
uniprot id: A0A3B4DR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

42514:gdf6a
gene id: 42514:gdf6a
uniprot id: A0A3B4DNR0
names: Similarity
messages: Belongs to the TGF-beta family.

42514:LOC108427970
gene id: 42514:LOC108427970
uniprot id: A0A3B4CIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

42514:rhot2
gene id: 42514:rhot2
uniprot id: A0A3B4DSH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

42514:ilvbl
gene id: 42514:ilvbl
uniprot id: A0A3B4DY13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPP enzyme family.
messages: Membrane

42514:elovl5
gene id: 42514:elovl5
uniprot id: A0A3B4D380
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

42514:LOC108432978
gene id: 42514:LOC108432978
uniprot id: A0A3B4CFE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

42514:mrpl11
gene id: 42514:mrpl11
uniprot id: A0A3B4E7E6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

42514:letm2
gene id: 42514:letm2
uniprot id: A0A3B4CMX5
names: Subcellular Location Annotation
messages: Membrane

42514:peli2
gene id: 42514:peli2
uniprot id: A0A3B4CKD8
names: Similarity
messages: Belongs to the pellino family.

42514:wnt2
gene id: 42514:wnt2
uniprot id: A0A3B4CAW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:fam234b
gene id: 42514:fam234b
uniprot id: A0A3B4EFQ6
names: Similarity
messages: Belongs to the FAM234 family.

42514:ptpn11a
gene id: 42514:ptpn11a
uniprot id: A0A3B4C7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

42514:LOC108442255
gene id: 42514:LOC108442255
uniprot id: A0A3B4D0A7
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

42514:nmt1b
gene id: 42514:nmt1b
uniprot id: A0A3B4D5P5
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

42514:cadm4
gene id: 42514:cadm4
uniprot id: A0A3B4D8X0
uniprot id: A0A3B4EJ04
names: Similarity
messages: Belongs to the nectin family.

42514:LOC108436838
gene id: 42514:LOC108436838
uniprot id: A0A3B4E7Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:sst2
gene id: 42514:sst2
uniprot id: A0A3B4DB04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

42514:pola2
gene id: 42514:pola2
uniprot id: A0A3B4CPQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

42514:osbpl10b
gene id: 42514:osbpl10b
uniprot id: A0A3B4DRL5
names: Similarity
messages: Belongs to the OSBP family.

42514:b4galt7
gene id: 42514:b4galt7
uniprot id: A0A3B4D4Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:stxbp5b
gene id: 42514:stxbp5b
uniprot id: A0A3B4BLN8
uniprot id: A0A3B4BQ43
uniprot id: A0A3B4DI45
uniprot id: A0A3B4DI50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

42514:stxbp2
gene id: 42514:stxbp2
uniprot id: A0A3B4E3E5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

42514:arpp19b
gene id: 42514:arpp19b
uniprot id: A0A3B4BPQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

42514:mapkapk2b
gene id: 42514:mapkapk2b
uniprot id: A0A3B4DH78
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:zgpat
gene id: 42514:zgpat
uniprot id: A0A3B4DSB6
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108442505
gene id: 42514:LOC108442505
uniprot id: A0A3B4DW25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

42514:kif4
gene id: 42514:kif4
uniprot id: A0A3B4D7J8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:st3gal3b
gene id: 42514:st3gal3b
uniprot id: A0A3B4BWX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:pnpla7b
gene id: 42514:pnpla7b
uniprot id: A0A3B4E9H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:guk1b
gene id: 42514:guk1b
uniprot id: A0A3B4E483
names: Similarity
messages: Belongs to the guanylate kinase family.

42514:ccnt2a
gene id: 42514:ccnt2a
uniprot id: A0A3B4DDF7
names: Similarity
messages: Belongs to the cyclin family.

42514:ddx5
gene id: 42514:ddx5
uniprot id: A0A3B4BPS2
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:zgc:101731
gene id: 42514:zgc:101731
uniprot id: A0A3B4DFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: synaptosome

42514:LOC108436134
gene id: 42514:LOC108436134
uniprot id: A0A3B4CV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:cdkn1a
gene id: 42514:cdkn1a
uniprot id: A0A3B4DLX7
uniprot id: A0A3B4DPJ4
names: Similarity
messages: Belongs to the CDI family.

42514:LOC108418432
gene id: 42514:LOC108418432
uniprot id: A0A3B4EQP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:aldocb
gene id: 42514:aldocb
uniprot id: A0A3B4CCE9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

42514:fscn1a
gene id: 42514:fscn1a
uniprot id: A0A3B4D0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

42514:prune
gene id: 42514:prune
uniprot id: A0A3B4D6P9
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

42514:metrnla
gene id: 42514:metrnla
uniprot id: A0A3B4E410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

42514:LOC108437850
gene id: 42514:LOC108437850
uniprot id: A0A3B4CRP1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:trpc1
gene id: 42514:trpc1
uniprot id: A0A3B4DGJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

42514:shha
gene id: 42514:shha
uniprot id: A0A3B4E4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

42514:LOC108432827
gene id: 42514:LOC108432827
uniprot id: A0A3B4ED62
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:tut4
gene id: 42514:tut4
uniprot id: A0A3B4EBF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

42514:pspc1
gene id: 42514:pspc1
uniprot id: A0A3B4CJ86
names: Subcellular Location Annotation
messages: Nucleus speckle

42514:armc8
gene id: 42514:armc8
uniprot id: A0A3B4D6Q7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:taz
gene id: 42514:taz
uniprot id: A0A3B4EA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

42514:mapk3
gene id: 42514:mapk3
uniprot id: A0A3B4EA36
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

42514:fam189a1
gene id: 42514:fam189a1
uniprot id: A0A3B4DLK8
names: Similarity
messages: Belongs to the ENTREP family.

42514:pkp2
gene id: 42514:pkp2
uniprot id: A0A3B4CMB2
names: Similarity
messages: Belongs to the beta-catenin family.

42514:aqp11
gene id: 42514:aqp11
uniprot id: A0A3B4CKK7
uniprot id: A0A3B4E649
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:gapdhs
gene id: 42514:gapdhs
uniprot id: A0A3B4D954
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

42514:itgb7
gene id: 42514:itgb7
uniprot id: A0A3B4E0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

42514:si:ch211-112c15.8
gene id: 42514:si:ch211-112c15.8
uniprot id: A0A3B4CLG0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ccl20a.3
gene id: 42514:ccl20a.3
uniprot id: A0A3B4CZ16
uniprot id: A0A3B4EC86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

42514:LOC108435795
gene id: 42514:LOC108435795
uniprot id: A0A3B4CG01
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:ormdl2
gene id: 42514:ormdl2
uniprot id: A0A3B4DAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

42514:tpd52l1
gene id: 42514:tpd52l1
uniprot id: A0A3B4BYQ6
uniprot id: A0A3B4BYS7
uniprot id: A0A3B4DQA3
names: Similarity
messages: Belongs to the TPD52 family.

42514:stk35l
gene id: 42514:stk35l
uniprot id: A0A3B4C7V5
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108415768
gene id: 42514:LOC108415768
uniprot id: A0A3B4D4G2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:pgap3
gene id: 42514:pgap3
uniprot id: A0A3B4BWI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Golgi apparatus membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:pdpk1b
gene id: 42514:pdpk1b
uniprot id: A0A3B4DW50
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

42514:csnk1e
gene id: 42514:csnk1e
uniprot id: A0A3B4DSL5
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:scnm1
gene id: 42514:scnm1
uniprot id: A0A3B4DTL2
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

42514:vps26bl
gene id: 42514:vps26bl
uniprot id: A0A3B4CRM8
names: Similarity
messages: Belongs to the VPS26 family.

42514:fgfr3
gene id: 42514:fgfr3
uniprot id: A0A3B4E2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:cse1l
gene id: 42514:cse1l
uniprot id: A0A3B4DVD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

42514:si:rp71-39b20.4
gene id: 42514:si:rp71-39b20.4
uniprot id: A0A3B4EM96
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108429169
gene id: 42514:LOC108429169
uniprot id: A0A3B4C270
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dgkab
gene id: 42514:dgkab
uniprot id: A0A3B4BRL8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

42514:galnt1
gene id: 42514:galnt1
uniprot id: A0A3B4D952
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:aasdh
gene id: 42514:aasdh
uniprot id: A0A3B4DJP7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:LOC108425037
gene id: 42514:LOC108425037
uniprot id: A0A3B4E6X0
names: Subcellular Location Annotation
messages: Membrane

42514:crygs2
gene id: 42514:crygs2
uniprot id: A0A3B4D7S9
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:nfil3
gene id: 42514:nfil3
uniprot id: A0A3B4CQ21
names: Similarity
messages: Belongs to the bZIP family. NFIL3 subfamily.

42514:eya1
gene id: 42514:eya1
uniprot id: A0A3B4D3K3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

42514:ddt
gene id: 42514:ddt
uniprot id: A0A3B4E3H4
names: Similarity
messages: Belongs to the MIF family.

42514:LOC108412190
gene id: 42514:LOC108412190
uniprot id: A0A3B4CSH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:pskh1
gene id: 42514:pskh1
uniprot id: A0A3B4E852
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:ube2r2
gene id: 42514:ube2r2
uniprot id: A0A3B4D0X0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:aplnr2
gene id: 42514:aplnr2
uniprot id: A0A3B4D4W9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:adcy6b
gene id: 42514:adcy6b
uniprot id: A0A3B4EIL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:eef1akmt2
gene id: 42514:eef1akmt2
uniprot id: A0A3B4CVH2
uniprot id: A0A3B4CVI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

42514:hs6st2
gene id: 42514:hs6st2
uniprot id: A0A3B4BRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

42514:LOC108416239
gene id: 42514:LOC108416239
uniprot id: A0A3B4DBR4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

42514:fam214a
gene id: 42514:fam214a
uniprot id: A0A3B4D1Y5
names: Similarity
messages: Belongs to the FAM214 family.

42514:ube2h
gene id: 42514:ube2h
uniprot id: A0A3B4EBL9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:pnpla7a
gene id: 42514:pnpla7a
uniprot id: A0A3B4BTY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:kmt5aa
gene id: 42514:kmt5aa
uniprot id: A0A3B4E2S4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

42514:mfsd14bb
gene id: 42514:mfsd14bb
uniprot id: A0A3B4BSU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

42514:efna3a
gene id: 42514:efna3a
uniprot id: A0A3B4E5Y3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:colgalt2
gene id: 42514:colgalt2
uniprot id: A0A3B4EGK8
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

42514:nhej1
gene id: 42514:nhej1
uniprot id: A0A3B4DS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XLF subfamily.
messages: Nucleus

42514:kdsr
gene id: 42514:kdsr
uniprot id: A0A3B4CH54
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:pfklb
gene id: 42514:pfklb
uniprot id: A0A3B4DK19
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:wasla
gene id: 42514:wasla
uniprot id: A0A3B4CIG0
uniprot id: A0A3B4E255
uniprot id: A0A3B4E3B9
names: Subcellular Location Annotation
messages: Nucleus

42514:calcrlb
gene id: 42514:calcrlb
uniprot id: A0A3B4EF28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

42514:ntrk2a
gene id: 42514:ntrk2a
uniprot id: A0A3B4CM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:loxa
gene id: 42514:loxa
uniprot id: A0A3B4DKA4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Contains 1 lysine tyrosylquinone.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

42514:LOC108412084
gene id: 42514:LOC108412084
uniprot id: A0A3B4CZU7
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

42514:LOC108428585
gene id: 42514:LOC108428585
uniprot id: A0A3B4DR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

42514:opn1sw2
gene id: 42514:opn1sw2
uniprot id: A0A3B4BY98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

42514:rbp7b
gene id: 42514:rbp7b
uniprot id: A0A3B4C4H6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:haus1
gene id: 42514:haus1
uniprot id: A0A3B4CNK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

42514:ndst2a
gene id: 42514:ndst2a
uniprot id: A0A3B4DJ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

42514:si:dkey-251i10.3
gene id: 42514:si:dkey-251i10.3
uniprot id: A0A3B4DJ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

42514:orai1a
gene id: 42514:orai1a
uniprot id: A0A3B4D8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

42514:polg2
gene id: 42514:polg2
uniprot id: A0A3B4DG71
names: Subcellular Location Annotation
messages: Mitochondrion

42514:sfxn1
gene id: 42514:sfxn1
uniprot id: A0A3B4D1T5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

42514:uts2a
gene id: 42514:uts2a
uniprot id: A0A3B4E9B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

42514:hoxc13a
gene id: 42514:hoxc13a
uniprot id: A0A3B4CUS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:si:dkey-51e6.1
gene id: 42514:si:dkey-51e6.1
uniprot id: A0A3B4E1Z3
names: Similarity
messages: Belongs to the janus family.

42514:spsb3a
gene id: 42514:spsb3a
uniprot id: A0A3B4C4L1
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

42514:tlcd2
gene id: 42514:tlcd2
uniprot id: A0A3B4BSG4
names: Subcellular Location Annotation
messages: Membrane

42514:ucn3l
gene id: 42514:ucn3l
uniprot id: A0A3B4DH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

42514:tub
gene id: 42514:tub
uniprot id: A0A3B4CEU8
uniprot id: A0A3B4CG95
uniprot id: A0A3B4CGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

42514:dmbx1a
gene id: 42514:dmbx1a
uniprot id: A0A3B4DMB0
names: Subcellular Location Annotation
messages: Nucleus

42514:cfap53
gene id: 42514:cfap53
uniprot id: A0A3B4CJC4
names: Similarity
messages: Belongs to the CFAP53 family.

42514:gpr137bb
gene id: 42514:gpr137bb
uniprot id: A0A3B4DT65
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

42514:tagln3a
gene id: 42514:tagln3a
uniprot id: A0A3B4EPM9
names: Similarity
messages: Belongs to the calponin family.

42514:b4galt6
gene id: 42514:b4galt6
uniprot id: A0A3B4DDD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:LOC108427135
gene id: 42514:LOC108427135
uniprot id: A0A3B4ENI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:LOC108442150
gene id: 42514:LOC108442150
uniprot id: A0A3B4D923
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:ednraa
gene id: 42514:ednraa
uniprot id: A0A3B4CQR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

42514:tmem132e
gene id: 42514:tmem132e
uniprot id: A0A3B4CFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

42514:utp11
gene id: 42514:utp11
uniprot id: A0A3B4DBL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

42514:sox21b
gene id: 42514:sox21b
uniprot id: A0A3B4EH42
names: Subcellular Location Annotation
messages: Nucleus

42514:oxt
gene id: 42514:oxt
uniprot id: A0A3B4EC25
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

42514:slc12a8
gene id: 42514:slc12a8
uniprot id: A0A3B4C7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:LOC108433150
gene id: 42514:LOC108433150
uniprot id: A0A3B4DMN3
names: Subcellular Location Annotation
messages: Membrane

42514:ca12
gene id: 42514:ca12
uniprot id: A0A3B4C9Z3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:LOC108433756
gene id: 42514:LOC108433756
uniprot id: A0A3B4BXI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

42514:tefm
gene id: 42514:tefm
uniprot id: A0A3B4DBN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEFM family.
messages: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.
messages: mitochondrion nucleoid

42514:chsy1
gene id: 42514:chsy1
uniprot id: A0A3B4DWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

42514:valopb
gene id: 42514:valopb
uniprot id: A0A3B4DKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

42514:zdhhc15b
gene id: 42514:zdhhc15b
uniprot id: A0A3B4CTG0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:kcnq3
gene id: 42514:kcnq3
uniprot id: A0A3B4CQX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:ciao1
gene id: 42514:ciao1
uniprot id: A0A3B4DIM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins.

42514:mtmr12
gene id: 42514:mtmr12
uniprot id: A0A3B4D323
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Sarcoplasmic reticulum
messages: sarcomere

42514:gpc5a
gene id: 42514:gpc5a
uniprot id: A0A3B4CEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

42514:bmp3
gene id: 42514:bmp3
uniprot id: A0A3B4CNH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

42514:usp13
gene id: 42514:usp13
uniprot id: A0A3B4D9P5
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:grk1a
gene id: 42514:grk1a
uniprot id: A0A3B4C1X5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:akt3a
gene id: 42514:akt3a
uniprot id: A0A3B4DV56
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

42514:LOC108431231
gene id: 42514:LOC108431231
uniprot id: A0A3B4DZC7
names: Subcellular Location Annotation
messages: Membrane

42514:irg1l
gene id: 42514:irg1l
uniprot id: A0A3B4E8E6
names: Similarity
messages: Belongs to the PrpD family.

42514:nudcd1
gene id: 42514:nudcd1
uniprot id: A0A3B4CUT5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:LOC108443500
gene id: 42514:LOC108443500
uniprot id: A0A3B4CEW5
names: Subcellular Location Annotation
messages: Membrane

42514:rps15a
gene id: 42514:rps15a
uniprot id: A0A3B4C061
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

42514:LOC108436869
gene id: 42514:LOC108436869
uniprot id: A0A3B4D5B1
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108434667
gene id: 42514:LOC108434667
uniprot id: A0A3B4CJT3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Nucleus outer membrane

42514:exosc2
gene id: 42514:exosc2
uniprot id: A0A3B4DYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

42514:arfgef1
gene id: 42514:arfgef1
uniprot id: A0A3B4CNR2
uniprot id: A0A3B4CQI0
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

42514:LOC108410557
gene id: 42514:LOC108410557
uniprot id: A0A3B4CTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

42514:bzw1a
gene id: 42514:bzw1a
uniprot id: A0A3B4BNN1
names: Similarity
messages: Belongs to the BZW family.

42514:rorc
gene id: 42514:rorc
uniprot id: A0A3B4CUX9
uniprot id: A0A3B4CVK3
uniprot id: A0A3B4E799
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:gins3
gene id: 42514:gins3
uniprot id: A0A3B4C0T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

42514:pdss1
gene id: 42514:pdss1
uniprot id: A0A3B4EMY4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

42514:mogat3b
gene id: 42514:mogat3b
uniprot id: A0A3B4DXX6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:nop14
gene id: 42514:nop14
uniprot id: A0A3B4EKC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

42514:mpc2a
gene id: 42514:mpc2a
uniprot id: A0A3B4D6T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108433597
gene id: 42514:LOC108433597
uniprot id: A0A3B4CEX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

42514:sypl1
gene id: 42514:sypl1
uniprot id: A0A3B4D4R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:LOC108444160
gene id: 42514:LOC108444160
uniprot id: A0A3B4CPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:psmb4
gene id: 42514:psmb4
uniprot id: A0A3B4ENX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

42514:etf1b
gene id: 42514:etf1b
uniprot id: A0A3B4CXK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

42514:pigk
gene id: 42514:pigk
uniprot id: A0A3B4CB68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

42514:syk
gene id: 42514:syk
uniprot id: A0A3B4CS48
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

42514:fbxo45
gene id: 42514:fbxo45
uniprot id: A0A3B4CNY9
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

42514:LOC108410546
gene id: 42514:LOC108410546
uniprot id: A0A3B4E9K8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

42514:psmb10
gene id: 42514:psmb10
uniprot id: A0A3B4D482
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

42514:f3a
gene id: 42514:f3a
uniprot id: A0A3B4CVG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

42514:LOC108444462
gene id: 42514:LOC108444462
uniprot id: A0A3B4BSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

42514:exoc5
gene id: 42514:exoc5
uniprot id: A0A3B4E3A9
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

42514:LOC108413650
gene id: 42514:LOC108413650
uniprot id: A0A3B4E0L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

42514:wdr4
gene id: 42514:wdr4
uniprot id: A0A3B4E1K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit METTL1.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

42514:atp1b1b
gene id: 42514:atp1b1b
uniprot id: A0A3B4D4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

42514:top1
gene id: 42514:top1
uniprot id: A0A3B4EDA2
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

42514:LOC108430275
gene id: 42514:LOC108430275
uniprot id: A0A3B4EPQ3
uniprot id: A0A3B4EQ88
names: Subunit
messages: Interacts with KCNJ11.

42514:LOC108415359
gene id: 42514:LOC108415359
uniprot id: A0A3B4CNC8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

42514:kpna4
gene id: 42514:kpna4
uniprot id: A0A3B4BTG8
names: Similarity
messages: Belongs to the importin alpha family.

42514:LOC108434641
gene id: 42514:LOC108434641
uniprot id: A0A3B4E765
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:arl11
gene id: 42514:arl11
uniprot id: A0A3B4D5M6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

42514:primpol
gene id: 42514:primpol
uniprot id: A0A3B4D5X7
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

42514:rap1gds1
gene id: 42514:rap1gds1
uniprot id: A0A3B4BXS7
uniprot id: A0A3B4C155
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: cytosol

42514:psmb8a
gene id: 42514:psmb8a
uniprot id: A0A3B4DQ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

42514:ruvbl1
gene id: 42514:ruvbl1
uniprot id: A0A3B4CIC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

42514:adma
gene id: 42514:adma
uniprot id: A0A3B4DYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

42514:dnase2b
gene id: 42514:dnase2b
uniprot id: A0A3B4CIB4
names: Similarity
messages: Belongs to the DNase II family.

42514:apln
gene id: 42514:apln
uniprot id: A0A3B4CSG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

42514:timm23a
gene id: 42514:timm23a
uniprot id: A0A3B4ELD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

42514:LOC108414341
gene id: 42514:LOC108414341
uniprot id: A0A3B4DHW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

42514:slc46a1
gene id: 42514:slc46a1
uniprot id: A0A3B4BSW1
names: Subcellular Location Annotation
messages: Membrane

42514:clgn
gene id: 42514:clgn
uniprot id: A0A3B4CCN5
names: Similarity
messages: Belongs to the calreticulin family.

42514:arf3b
gene id: 42514:arf3b
uniprot id: A0A3B4D532
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:snx14
gene id: 42514:snx14
uniprot id: A0A3B4CA77
uniprot id: A0A3B4CCE8
names: Similarity
messages: Belongs to the sorting nexin family.

42514:si:ch211-22d5.2
gene id: 42514:si:ch211-22d5.2
uniprot id: A0A3B4CEM0
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108441388
gene id: 42514:LOC108441388
uniprot id: A0A3B4C8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

42514:tmem41ab
gene id: 42514:tmem41ab
uniprot id: A0A3B4BYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

42514:LOC108432124
gene id: 42514:LOC108432124
uniprot id: A0A3B4DFB2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:nudt15
gene id: 42514:nudt15
uniprot id: A0A3B4CQJ0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

42514:acox3
gene id: 42514:acox3
uniprot id: A0A3B4C3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

42514:LOC108431693
gene id: 42514:LOC108431693
uniprot id: A0A3B4CR80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

42514:mmaa
gene id: 42514:mmaa
uniprot id: A0A3B4CR22
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

42514:cryl1
gene id: 42514:cryl1
uniprot id: A0A3B4BZ40
uniprot id: A0A3B4BZ67
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

42514:ern1
gene id: 42514:ern1
uniprot id: A0A3B4DGS3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108430250
gene id: 42514:LOC108430250
uniprot id: A0A3B4BV08
uniprot id: A0A3B4BV14
uniprot id: A0A3B4BY86
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

42514:LOC108429273
gene id: 42514:LOC108429273
uniprot id: A0A3B4BXE8
uniprot id: A0A3B4C060
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

42514:ptenb
gene id: 42514:ptenb
uniprot id: A0A3B4DNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

42514:slc30a1b
gene id: 42514:slc30a1b
uniprot id: A0A3B4CJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

42514:ppp2r5b
gene id: 42514:ppp2r5b
uniprot id: A0A3B4E7F2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

42514:LOC108438909
gene id: 42514:LOC108438909
uniprot id: A0A3B4CYB9
names: Subcellular Location Annotation
messages: Membrane

42514:adnp2a
gene id: 42514:adnp2a
uniprot id: A0A3B4D9T3
names: Subcellular Location Annotation
messages: Nucleus

42514:eef1da
gene id: 42514:eef1da
uniprot id: A0A3B4BV57
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

42514:hacd2
gene id: 42514:hacd2
uniprot id: A0A3B4DBB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:kynu
gene id: 42514:kynu
uniprot id: A0A3B4EFD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

42514:lgalslb
gene id: 42514:lgalslb
uniprot id: A0A3B4DXU8
names: Function
messages: Does not bind lactose, and may not bind carbohydrates.

42514:smad2
gene id: 42514:smad2
uniprot id: A0A3B4D7F9
uniprot id: A0A3B4DA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:rab3il1
gene id: 42514:rab3il1
uniprot id: A0A3B4EH39
names: Similarity
messages: Belongs to the SEC2 family.

42514:rbp4
gene id: 42514:rbp4
uniprot id: A0A3B4C841
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

42514:shrprbck1r
gene id: 42514:shrprbck1r
uniprot id: A0A3B4DIN6
names: Similarity
messages: Belongs to the RBR family.

42514:xylb
gene id: 42514:xylb
uniprot id: A0A3B4EI44
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

42514:zgc:172270
gene id: 42514:zgc:172270
uniprot id: A0A3B4E3Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

42514:npm3
gene id: 42514:npm3
uniprot id: A0A3B4CFF4
names: Similarity
messages: Belongs to the nucleoplasmin family.

42514:LOC108417048
gene id: 42514:LOC108417048
uniprot id: A0A3B4DDF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:aldh18a1
gene id: 42514:aldh18a1
uniprot id: A0A3B4D9A3
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

42514:eya4
gene id: 42514:eya4
uniprot id: A0A3B4D5N8
uniprot id: A0A3B4EJ87
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Nucleus

42514:mat2b
gene id: 42514:mat2b
uniprot id: A0A3B4DDV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

42514:vegfc
gene id: 42514:vegfc
uniprot id: A0A3B4C6P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

42514:ccdc86
gene id: 42514:ccdc86
uniprot id: A0A3B4DMU6
names: Subcellular Location Annotation
messages: Nucleus

42514:chmp4c
gene id: 42514:chmp4c
uniprot id: A0A3B4DLE8
names: Similarity
messages: Belongs to the SNF7 family.

42514:gpr137c
gene id: 42514:gpr137c
uniprot id: A0A3B4CBI0
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

42514:coro2bb
gene id: 42514:coro2bb
uniprot id: A0A3B4BSN9
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:il10
gene id: 42514:il10
uniprot id: A0A3B4C0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

42514:kcng4a
gene id: 42514:kcng4a
uniprot id: A0A3B4E6A6
names: Subcellular Location Annotation
messages: Membrane

42514:supt20
gene id: 42514:supt20
uniprot id: A0A3B4EBD7
names: Similarity
messages: Belongs to the SPT20 family.

42514:poll
gene id: 42514:poll
uniprot id: A0A3B4DP76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus

42514:fam53c
gene id: 42514:fam53c
uniprot id: A0A3B4C8M3
names: Similarity
messages: Belongs to the FAM53 family.

42514:tmem30b
gene id: 42514:tmem30b
uniprot id: A0A3B4EGK3
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

42514:mfn1b
gene id: 42514:mfn1b
uniprot id: A0A3B4BPJ3
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

42514:LOC108412826
gene id: 42514:LOC108412826
uniprot id: A0A3B4CL74
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

42514:lig3
gene id: 42514:lig3
uniprot id: A0A3B4E3M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

42514:LOC108431411
gene id: 42514:LOC108431411
uniprot id: A0A3B4C3R1
names: Similarity
messages: Belongs to the RBR family.

42514:si:ch211-200p22.4
gene id: 42514:si:ch211-200p22.4
uniprot id: A0A3B4C967
uniprot id: A0A3B4DU82
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

42514:egr3
gene id: 42514:egr3
uniprot id: A0A3B4E9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

42514:txnipa
gene id: 42514:txnipa
uniprot id: A0A3B4DFP2
names: Similarity
messages: Belongs to the arrestin family.

42514:trpm6
gene id: 42514:trpm6
uniprot id: A0A3B4DNN8
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

42514:psd3l
gene id: 42514:psd3l
uniprot id: A0A3B4EBU6
names: Subcellular Location Annotation
messages: ruffle membrane

42514:gpd1l
gene id: 42514:gpd1l
uniprot id: A0A3B4DRK3
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

42514:hnf4g
gene id: 42514:hnf4g
uniprot id: A0A3B4CX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

42514:LOC108430768
gene id: 42514:LOC108430768
uniprot id: A0A3B4CF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle

42514:stat1a
gene id: 42514:stat1a
uniprot id: A0A3B4CSG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108410647
gene id: 42514:LOC108410647
uniprot id: A0A3B4E655
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dda1
gene id: 42514:dda1
uniprot id: A0A3B4DRZ9
names: Similarity
messages: Belongs to the DDA1 family.

42514:LOC108414952
gene id: 42514:LOC108414952
uniprot id: A0A3B4DRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

42514:LOC108424192
gene id: 42514:LOC108424192
uniprot id: A0A3B4EMJ4
uniprot id: A0A3B4EPE3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:wee2
gene id: 42514:wee2
uniprot id: A0A3B4CA31
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

42514:LOC108412772
gene id: 42514:LOC108412772
uniprot id: A0A3B4CXH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

42514:npr3
gene id: 42514:npr3
uniprot id: A0A3B4D528
names: Subcellular Location Annotation
messages: Membrane

42514:slc18a3a
gene id: 42514:slc18a3a
uniprot id: A0A3B4DL37
names: Subcellular Location Annotation
messages: Membrane

42514:rabep1
gene id: 42514:rabep1
uniprot id: A0A3B4E1G1
uniprot id: A0A3B4E1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

42514:LOC108442162
gene id: 42514:LOC108442162
uniprot id: A0A3B4DAA2
uniprot id: A0A3B4EMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

42514:hlfb
gene id: 42514:hlfb
uniprot id: A0A3B4C6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

42514:tbxta
gene id: 42514:tbxta
uniprot id: A0A3B4C4D3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:lpgat1
gene id: 42514:lpgat1
uniprot id: A0A3B4DU01
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:alg14
gene id: 42514:alg14
uniprot id: A0A3B4CXI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG14 family.
messages: Membrane
messages: Nucleus membrane

42514:derl2
gene id: 42514:derl2
uniprot id: A0A3B4E1F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108413599
gene id: 42514:LOC108413599
uniprot id: A0A3B4DZ42
names: Subcellular Location Annotation
messages: Membrane

42514:brms1
gene id: 42514:brms1
uniprot id: A0A3B4DN90
names: Subcellular Location Annotation
messages: Nucleus

42514:casq2
gene id: 42514:casq2
uniprot id: A0A3B4BS22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

42514:axin1
gene id: 42514:axin1
uniprot id: A0A3B4C1L0
uniprot id: A0A3B4DQJ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

42514:ca9
gene id: 42514:ca9
uniprot id: A0A3B4CWX5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:syngr3b
gene id: 42514:syngr3b
uniprot id: A0A3B4C0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

42514:sat1a.2
gene id: 42514:sat1a.2
uniprot id: A0A3B4CPE5
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

42514:LOC108425742
gene id: 42514:LOC108425742
uniprot id: A0A3B4CBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

42514:rab39ba
gene id: 42514:rab39ba
uniprot id: A0A3B4DZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

42514:ppm1bb
gene id: 42514:ppm1bb
uniprot id: A0A3B4DKJ4
uniprot id: A0A3B4DP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

42514:pcyt1bb
gene id: 42514:pcyt1bb
uniprot id: A0A3B4DY06
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

42514:lhx9
gene id: 42514:lhx9
uniprot id: A0A3B4DX99
names: Subcellular Location Annotation
messages: Nucleus

42514:rln3b
gene id: 42514:rln3b
uniprot id: A0A3B4D7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

42514:ackr3a
gene id: 42514:ackr3a
uniprot id: A0A3B4CZN7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:trhrb
gene id: 42514:trhrb
uniprot id: A0A3B4EAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

42514:tdo2a
gene id: 42514:tdo2a
uniprot id: A0A3B4E8P7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:engase
gene id: 42514:engase
uniprot id: A0A3B4C9D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

42514:nsg1
gene id: 42514:nsg1
uniprot id: A0A3B4C4V2
names: Similarity
messages: Belongs to the NSG family.

42514:cavin2a
gene id: 42514:cavin2a
uniprot id: A0A3B4D8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

42514:dmap1
gene id: 42514:dmap1
uniprot id: A0A3B4E6Q3
names: Subcellular Location Annotation
messages: Nucleus

42514:pfdn5
gene id: 42514:pfdn5
uniprot id: A0A3B4CDF9
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

42514:th
gene id: 42514:th
uniprot id: A0A3B4DPT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: axon
messages: perinuclear region

42514:opn7b
gene id: 42514:opn7b
uniprot id: A0A3B4EG34
names: Subcellular Location Annotation
messages: Membrane

42514:ncaph
gene id: 42514:ncaph
uniprot id: A0A3B4D0E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

42514:si:ch211-113j14.1
gene id: 42514:si:ch211-113j14.1
uniprot id: A0A3B4EF23
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:gphnb
gene id: 42514:gphnb
uniprot id: A0A3B4C0S2
uniprot id: A0A3B4C423
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

42514:chmp4ba
gene id: 42514:chmp4ba
uniprot id: A0A3B4DU08
names: Similarity
messages: Belongs to the SNF7 family.

42514:LOC108431543
gene id: 42514:LOC108431543
uniprot id: A0A3B4BSM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Secreted

42514:gstt1a
gene id: 42514:gstt1a
uniprot id: A0A3B4C0H5
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

42514:LOC108441187
gene id: 42514:LOC108441187
uniprot id: A0A3B4C793
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:grik2
gene id: 42514:grik2
uniprot id: A0A3B4CGT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:antxr1c
gene id: 42514:antxr1c
uniprot id: A0A3B4EEQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

42514:fam160a2
gene id: 42514:fam160a2
uniprot id: A0A3B4DJH0
names: Similarity
messages: Belongs to the FHIP family.

42514:LOC108437766
gene id: 42514:LOC108437766
uniprot id: A0A3B4D3U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

42514:rab21
gene id: 42514:rab21
uniprot id: A0A3B4CWL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

42514:fez2
gene id: 42514:fez2
uniprot id: A0A3B4DPQ3
uniprot id: A0A3B4DS88
names: Similarity
messages: Belongs to the zygin family.

42514:LOC108432818
gene id: 42514:LOC108432818
uniprot id: A0A3B4ECA3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:uncx
gene id: 42514:uncx
uniprot id: A0A3B4BYH7
names: Subcellular Location Annotation
messages: Nucleus

42514:plpp5
gene id: 42514:plpp5
uniprot id: A0A3B4D0A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:slc6a11b
gene id: 42514:slc6a11b
uniprot id: A0A3B4BU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:arpc4
gene id: 42514:arpc4
uniprot id: A0A3B4E431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

42514:LOC108443606
gene id: 42514:LOC108443606
uniprot id: A0A3B4C3Z2
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:rgs8
gene id: 42514:rgs8
uniprot id: A0A3B4C3F6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

42514:fntb
gene id: 42514:fntb
uniprot id: A0A3B4C2P8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

42514:mrpl41
gene id: 42514:mrpl41
uniprot id: A0A3B4CUN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

42514:LOC108430825
gene id: 42514:LOC108430825
uniprot id: A0A3B4DZF6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:slitrk3a
gene id: 42514:slitrk3a
uniprot id: A0A3B4E955
names: Similarity
messages: Belongs to the SLITRK family.

42514:tmem115
gene id: 42514:tmem115
uniprot id: A0A3B4E8S0
names: Subcellular Location Annotation
messages: Membrane

42514:syt1a
gene id: 42514:syt1a
uniprot id: A0A3B4DW00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

42514:wdr48b
gene id: 42514:wdr48b
uniprot id: A0A3B4EIC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Endosome
messages: Late endosome

42514:taf9
gene id: 42514:taf9
uniprot id: A0A3B4CG15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

42514:pdss2
gene id: 42514:pdss2
uniprot id: A0A3B4DT08
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

42514:aar2
gene id: 42514:aar2
uniprot id: A0A3B4CYA2
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

42514:LOC108424922
gene id: 42514:LOC108424922
uniprot id: A0A3B4EE24
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

42514:tent5ba
gene id: 42514:tent5ba
uniprot id: A0A3B4CXD4
names: Similarity
messages: Belongs to the TENT family.

42514:slc1a2b
gene id: 42514:slc1a2b
uniprot id: A0A3B4DH86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:unc5c
gene id: 42514:unc5c
uniprot id: A0A3B4CTL1
uniprot id: A0A3B4EAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

42514:lgalsla
gene id: 42514:lgalsla
uniprot id: A0A3B4C618
names: Function
messages: Does not bind lactose, and may not bind carbohydrates.

42514:LOC108411194
gene id: 42514:LOC108411194
uniprot id: A0A3B4DYC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

42514:chrnb3b
gene id: 42514:chrnb3b
uniprot id: A0A3B4DFZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:usp49
gene id: 42514:usp49
uniprot id: A0A3B4C026
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:erap2
gene id: 42514:erap2
uniprot id: A0A3B4DGR8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:naxe
gene id: 42514:naxe
uniprot id: A0A3B4BP77
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted

42514:zgc:66455
gene id: 42514:zgc:66455
uniprot id: A0A3B4DW65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:pla2g4f.1
gene id: 42514:pla2g4f.1
uniprot id: A0A3B4D6H6
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.

42514:atxn1a
gene id: 42514:atxn1a
uniprot id: A0A3B4C018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

42514:apodb
gene id: 42514:apodb
uniprot id: A0A3B4DHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

42514:tnfa
gene id: 42514:tnfa
uniprot id: A0A3B4EMD7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:sfxn5b
gene id: 42514:sfxn5b
uniprot id: A0A3B4D0V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

42514:rrm2b
gene id: 42514:rrm2b
uniprot id: A0A3B4DS93
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

42514:acbd5b
gene id: 42514:acbd5b
uniprot id: A0A3B4E4X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

42514:parp6b
gene id: 42514:parp6b
uniprot id: A0A3B4CEC5
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:gabrr1
gene id: 42514:gabrr1
uniprot id: A0A3B4C9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:dhrs3a
gene id: 42514:dhrs3a
uniprot id: A0A3B4CNM2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:cnksr2b
gene id: 42514:cnksr2b
uniprot id: A0A3B4DZV6
names: Similarity
messages: Belongs to the CNKSR family.

42514:igfbp1b
gene id: 42514:igfbp1b
uniprot id: A0A3B4BUF9
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:ap3s1
gene id: 42514:ap3s1
uniprot id: A0A3B4BRK8
uniprot id: A0A3B4BV15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

42514:LOC108426917
gene id: 42514:LOC108426917
uniprot id: A0A3B4DLA1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:rnf168
gene id: 42514:rnf168
uniprot id: A0A3B4C293
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Nucleus
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).

42514:im:7154036
gene id: 42514:im:7154036
uniprot id: A0A3B4CYP1
names: Similarity
messages: Belongs to the kindlin family.

42514:psat1
gene id: 42514:psat1
uniprot id: A0A3B4C4Z9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

42514:syndig1l
gene id: 42514:syndig1l
uniprot id: A0A3B4BYQ8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

42514:otog
gene id: 42514:otog
uniprot id: A0A3B4EHW5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dgat1a
gene id: 42514:dgat1a
uniprot id: A0A3B4CJQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

42514:tsn
gene id: 42514:tsn
uniprot id: A0A3B4CPA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

42514:trmt2a
gene id: 42514:trmt2a
uniprot id: A0A3B4CHK6
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:reep6
gene id: 42514:reep6
uniprot id: A0A3B4D2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

42514:pgm5
gene id: 42514:pgm5
uniprot id: A0A3B4CDJ8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

42514:LOC108443086
gene id: 42514:LOC108443086
uniprot id: A0A3B4C7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

42514:nkain2
gene id: 42514:nkain2
uniprot id: A0A3B4E056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

42514:brk1
gene id: 42514:brk1
uniprot id: A0A3B4E2U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

42514:isl2a
gene id: 42514:isl2a
uniprot id: A0A3B4DZU2
names: Subcellular Location Annotation
messages: Nucleus

42514:tmem267
gene id: 42514:tmem267
uniprot id: A0A3B4EN60
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108439342
gene id: 42514:LOC108439342
uniprot id: A0A3B4D9R0
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:atg9b
gene id: 42514:atg9b
uniprot id: A0A3B4CFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

42514:cs
gene id: 42514:cs
uniprot id: A0A3B4ECP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

42514:tlr18
gene id: 42514:tlr18
uniprot id: A0A3B4C5S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

42514:tmem126a
gene id: 42514:tmem126a
uniprot id: A0A3B4DJI5
names: Subcellular Location Annotation
messages: Membrane

42514:gpr20
gene id: 42514:gpr20
uniprot id: A0A3B4DBH2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108436432
gene id: 42514:LOC108436432
uniprot id: A0A3B4DSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

42514:zgc:162989
gene id: 42514:zgc:162989
uniprot id: A0A3B4CU86
names: Similarity
messages: Belongs to the PP1 inhibitor family.

42514:sfrp1b
gene id: 42514:sfrp1b
uniprot id: A0A3B4EGZ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:fam193b
gene id: 42514:fam193b
uniprot id: A0A3B4DV94
names: Similarity
messages: Belongs to the FAM193 family.

42514:mpp7a
gene id: 42514:mpp7a
uniprot id: A0A3B4DSJ8
names: Similarity
messages: Belongs to the MAGUK family.

42514:runx2b
gene id: 42514:runx2b
uniprot id: A0A3B4E6I9
names: Subcellular Location Annotation
messages: Nucleus

42514:gpkow
gene id: 42514:gpkow
uniprot id: A0A3B4DK80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus

42514:gabrr3a
gene id: 42514:gabrr3a
uniprot id: A0A3B4DZM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:si:ch211-1i11.3
gene id: 42514:si:ch211-1i11.3
uniprot id: A0A3B4CDU9
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

42514:snx1a
gene id: 42514:snx1a
uniprot id: A0A3B4END3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

42514:LOC108426052
gene id: 42514:LOC108426052
uniprot id: A0A3B4CYX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:smim22
gene id: 42514:smim22
uniprot id: A0A3B4DVB1
names: Subcellular Location Annotation
messages: Membrane

42514:henmt1
gene id: 42514:henmt1
uniprot id: A0A3B4DKY4
names: Similarity
messages: Belongs to the methyltransferase superfamily. HEN1 family.

42514:eef1g
gene id: 42514:eef1g
uniprot id: A0A3B4D5R3
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

42514:zfyve16
gene id: 42514:zfyve16
uniprot id: A0A3B4DUJ4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

42514:sgsm2
gene id: 42514:sgsm2
uniprot id: A0A3B4BY70
uniprot id: A0A3B4C160
names: Similarity
messages: Belongs to the RUTBC family.

42514:eloca
gene id: 42514:eloca
uniprot id: A0A3B4D142
names: Similarity
messages: Belongs to the SKP1 family.

42514:LOC108440226
gene id: 42514:LOC108440226
uniprot id: A0A3B4C331
names: Similarity
messages: Belongs to the globin family.

42514:mvk
gene id: 42514:mvk
uniprot id: A0A3B4BUV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

42514:mipa
gene id: 42514:mipa
uniprot id: A0A3B4EJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:aph1b
gene id: 42514:aph1b
uniprot id: A0A3B4BQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

42514:dnm1l
gene id: 42514:dnm1l
uniprot id: A0A3B4CRT8
uniprot id: A0A3B4CRU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Endomembrane system
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: clathrin-coated pit
messages: cytosol
messages: synaptic vesicle membrane

42514:borcs8
gene id: 42514:borcs8
uniprot id: A0A3B4CS76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

42514:homer1b
gene id: 42514:homer1b
uniprot id: A0A3B4EPV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

42514:slc25a51b
gene id: 42514:slc25a51b
uniprot id: A0A3B4D4S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:LOC108431923
gene id: 42514:LOC108431923
uniprot id: A0A3B4DUK0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

42514:kcnj9
gene id: 42514:kcnj9
uniprot id: A0A3B4C3C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

42514:aig1
gene id: 42514:aig1
uniprot id: A0A3B4D8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

42514:nf2b
gene id: 42514:nf2b
uniprot id: A0A3B4E1Z8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

42514:arhgdia
gene id: 42514:arhgdia
uniprot id: A0A3B4C9Q0
names: Similarity
messages: Belongs to the Rho GDI family.

42514:dharma
gene id: 42514:dharma
uniprot id: A0A3B4EQW7
names: Subcellular Location Annotation
messages: Nucleus

42514:actc2
gene id: 42514:actc2
uniprot id: A0A3B4DE56
names: Similarity
messages: Belongs to the actin family.

42514:exo1
gene id: 42514:exo1
uniprot id: A0A3B4C0G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

42514:LOC108411165
gene id: 42514:LOC108411165
uniprot id: A0A3B4CDC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane

42514:pcxb
gene id: 42514:pcxb
uniprot id: A0A3B4DSE5
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

42514:wipi2
gene id: 42514:wipi2
uniprot id: A0A3B4CZJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure membrane

42514:gtf2h4
gene id: 42514:gtf2h4
uniprot id: A0A3B4DAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB2 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

42514:dipk1c
gene id: 42514:dipk1c
uniprot id: A0A3B4BMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

42514:scrn3
gene id: 42514:scrn3
uniprot id: A0A3B4CS05
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

42514:alkbh8
gene id: 42514:alkbh8
uniprot id: A0A3B4CUB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

42514:ube2ia
gene id: 42514:ube2ia
uniprot id: A0A3B4DM14
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:ccdc153
gene id: 42514:ccdc153
uniprot id: A0A3B4EIU9
names: Similarity
messages: Belongs to the UPF0610 family.

42514:LOC108438923
gene id: 42514:LOC108438923
uniprot id: A0A3B4CZW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:jag1b
gene id: 42514:jag1b
uniprot id: A0A3B4E235
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

42514:LOC108430017
gene id: 42514:LOC108430017
uniprot id: A0A3B4BZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: nucleoplasm

42514:LOC108441353
gene id: 42514:LOC108441353
uniprot id: A0A3B4DZZ2
names: Subcellular Location Annotation
messages: Membrane

42514:clcn5b
gene id: 42514:clcn5b
uniprot id: A0A3B4DXD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

42514:sf3a1
gene id: 42514:sf3a1
uniprot id: A0A3B4CXX8
names: Subcellular Location Annotation
messages: Nucleus

42514:slc5a9
gene id: 42514:slc5a9
uniprot id: A0A3B4CM18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:btf3l4
gene id: 42514:btf3l4
uniprot id: A0A3B4DSK5
names: Similarity
messages: Belongs to the NAC-beta family.

42514:LOC108440017
gene id: 42514:LOC108440017
uniprot id: A0A3B4CX21
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:adrb2b
gene id: 42514:adrb2b
uniprot id: A0A3B4CKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:gabrb1
gene id: 42514:gabrb1
uniprot id: A0A3B4CD53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:rpia
gene id: 42514:rpia
uniprot id: A0A3B4E4B6
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

42514:sorbs2a
gene id: 42514:sorbs2a
uniprot id: A0A3B4BZU6
names: Subcellular Location Annotation
messages: focal adhesion

42514:LOC108440424
gene id: 42514:LOC108440424
uniprot id: A0A3B4ELT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

42514:ppm1g
gene id: 42514:ppm1g
uniprot id: A0A3B4C2X8
names: Similarity
messages: Belongs to the PP2C family.

42514:LOC108427189
gene id: 42514:LOC108427189
uniprot id: A0A3B4D2R5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:map4k2
gene id: 42514:map4k2
uniprot id: A0A3B4C9J1
uniprot id: A0A3B4CB08
uniprot id: A0A3B4DXN7
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

42514:slc17a5
gene id: 42514:slc17a5
uniprot id: A0A3B4DN62
names: Subcellular Location Annotation
messages: Membrane

42514:tegt
gene id: 42514:tegt
uniprot id: A0A3B4BL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

42514:mnat1
gene id: 42514:mnat1
uniprot id: A0A3B4CY66
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

42514:dnmt1
gene id: 42514:dnmt1
uniprot id: A0A3B4CJF5
uniprot id: A0A3B4E434
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

42514:slc35a3a
gene id: 42514:slc35a3a
uniprot id: A0A3B4D6B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

42514:grik4
gene id: 42514:grik4
uniprot id: A0A3B4D4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:guf1
gene id: 42514:guf1
uniprot id: A0A3B4D536
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

42514:rad23ab
gene id: 42514:rad23ab
uniprot id: A0A3B4CLF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Nucleus

42514:LOC108444230
gene id: 42514:LOC108444230
uniprot id: A0A3B4CF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:pfkfb2a
gene id: 42514:pfkfb2a
uniprot id: A0A3B4EC52
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

42514:mrps23
gene id: 42514:mrps23
uniprot id: A0A3B4CHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Mitochondrion

42514:slc8a2b
gene id: 42514:slc8a2b
uniprot id: A0A3B4EEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

42514:atf2
gene id: 42514:atf2
uniprot id: A0A3B4CWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a dimer and can form a homodimer in the absence of DNA.
messages: Nucleus
messages: Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3').

42514:mapk7
gene id: 42514:mapk7
uniprot id: A0A3B4CYC0
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

42514:hdac1
gene id: 42514:hdac1
uniprot id: A0A3B4DHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also functions as deacetylase for non-histone proteins.
messages: Nucleus

42514:mpped2
gene id: 42514:mpped2
uniprot id: A0A3B4CI08
names: Similarity
messages: Belongs to the UPF0046 family.

42514:prkg1b
gene id: 42514:prkg1b
uniprot id: A0A3B4BQF6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

42514:kif13bb
gene id: 42514:kif13bb
uniprot id: A0A3B4BZQ3
uniprot id: A0A3B4BZT6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:gabpa
gene id: 42514:gabpa
uniprot id: A0A3B4E8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:LOC108411940
gene id: 42514:LOC108411940
uniprot id: A0A3B4C4I2
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

42514:gmds
gene id: 42514:gmds
uniprot id: A0A3B4D168
uniprot id: A0A3B4EHS5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

42514:nup210
gene id: 42514:nup210
uniprot id: A0A3B4D0M0
names: Similarity
messages: Belongs to the NUP210 family.

42514:creb1b
gene id: 42514:creb1b
uniprot id: A0A3B4D8S7
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108440197
gene id: 42514:LOC108440197
uniprot id: A0A3B4CG44
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:rbp4l
gene id: 42514:rbp4l
uniprot id: A0A3B4BVU6
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

42514:erg
gene id: 42514:erg
uniprot id: A0A3B4CLM0
uniprot id: A0A3B4E6M4
uniprot id: A0A3B4E6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:thbs3a
gene id: 42514:thbs3a
uniprot id: A0A3B4BSE4
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tnip2
gene id: 42514:tnip2
uniprot id: A0A3B4CKM0
names: Subcellular Location Annotation
messages: Cytoplasm

42514:mrpl32
gene id: 42514:mrpl32
uniprot id: A0A3B4CEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL32 family.
messages: Cytoplasm

42514:plac8.2
gene id: 42514:plac8.2
uniprot id: A0A3B4DLH8
names: Similarity
messages: Belongs to the cornifelin family.

42514:LOC108425535
gene id: 42514:LOC108425535
uniprot id: A0A3B4ECN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

42514:acsl6
gene id: 42514:acsl6
uniprot id: A0A3B4CET8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

42514:LOC108412730
gene id: 42514:LOC108412730
uniprot id: A0A3B4D497
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:irgq1
gene id: 42514:irgq1
uniprot id: A0A3B4EH77
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:LOC108424615
gene id: 42514:LOC108424615
uniprot id: A0A3B4BQY6
uniprot id: A0A3B4DIM1
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:dctn2
gene id: 42514:dctn2
uniprot id: A0A3B4E139
names: Function
names: Similarity
messages: Belongs to the dynactin subunit 2 family.
messages: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

42514:atp10d
gene id: 42514:atp10d
uniprot id: A0A3B4DXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:asphd2
gene id: 42514:asphd2
uniprot id: A0A3B4CEA7
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

42514:LOC108411019
gene id: 42514:LOC108411019
uniprot id: A0A3B4EBD3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

42514:si:ch211-106h11.3
gene id: 42514:si:ch211-106h11.3
uniprot id: A0A3B4CAK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:acp5a
gene id: 42514:acp5a
uniprot id: A0A3B4DMI1
names: Cofactor
messages: Binds 2 iron ions per subunit.

42514:cacna1ha
gene id: 42514:cacna1ha
uniprot id: A0A3B4EG27
names: Subcellular Location Annotation
messages: Membrane

42514:pfn2l
gene id: 42514:pfn2l
uniprot id: A0A3B4CEY2
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

42514:tmem120a
gene id: 42514:tmem120a
uniprot id: A0A3B4CDA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

42514:hapln4
gene id: 42514:hapln4
uniprot id: A0A3B4CU45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:adam15
gene id: 42514:adam15
uniprot id: A0A3B4BNK4
uniprot id: A0A3B4BRS8
uniprot id: A0A3B4DJ41
uniprot id: A0A3B4DK14
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:inpp5l
gene id: 42514:inpp5l
uniprot id: A0A3B4CNU9
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

42514:zeb2a
gene id: 42514:zeb2a
uniprot id: A0A3B4DVW7
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

42514:otub1b
gene id: 42514:otub1b
uniprot id: A0A3B4CSU4
names: Similarity
messages: Belongs to the peptidase C65 family.

42514:LOC108437265
gene id: 42514:LOC108437265
uniprot id: A0A3B4D1V4
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108442659
gene id: 42514:LOC108442659
uniprot id: A0A3B4BRD1
names: Similarity
messages: Belongs to the FAM83 family.

42514:LOC108429853
gene id: 42514:LOC108429853
uniprot id: A0A3B4DLH1
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:vipr1a
gene id: 42514:vipr1a
uniprot id: A0A3B4ENX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

42514:ccr9a
gene id: 42514:ccr9a
uniprot id: A0A3B4DKP5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:npl
gene id: 42514:npl
uniprot id: A0A3B4D476
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

42514:heatr1
gene id: 42514:heatr1
uniprot id: A0A3B4EG87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

42514:mon1a
gene id: 42514:mon1a
uniprot id: A0A3B4D720
names: Function
names: Similarity
messages: Belongs to the MON1/SAND family.
messages: Plays an important role in membrane trafficking through the secretory apparatus.

42514:bmpr2a
gene id: 42514:bmpr2a
uniprot id: A0A3B4CS34
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

42514:dedd1
gene id: 42514:dedd1
uniprot id: A0A3B4E9X9
names: Subcellular Location Annotation
messages: nucleolus

42514:rdh10a
gene id: 42514:rdh10a
uniprot id: A0A3B4D1D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

42514:c6h2orf49
gene id: 42514:c6h2orf49
uniprot id: A0A3B4BWY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

42514:ift20
gene id: 42514:ift20
uniprot id: A0A3B4DQI2
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

42514:top3a
gene id: 42514:top3a
uniprot id: A0A3B4CZI1
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

42514:si:ch211-79m20.1
gene id: 42514:si:ch211-79m20.1
uniprot id: A0A3B4EL63
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:LOC108431121
gene id: 42514:LOC108431121
uniprot id: A0A3B4D5Q5
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:ptafr
gene id: 42514:ptafr
uniprot id: A0A3B4D2U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

42514:LOC108432463
gene id: 42514:LOC108432463
uniprot id: A0A3B4C0D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

42514:ypel3
gene id: 42514:ypel3
uniprot id: A0A3B4CZL4
names: Similarity
messages: Belongs to the yippee family.

42514:LOC108430776
gene id: 42514:LOC108430776
uniprot id: A0A3B4E2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:ppp2r5d
gene id: 42514:ppp2r5d
uniprot id: A0A3B4C3W3
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

42514:LOC108436755
gene id: 42514:LOC108436755
uniprot id: A0A3B4CX76
names: Similarity
messages: Belongs to the DTD family.

42514:oxtrl
gene id: 42514:oxtrl
uniprot id: A0A3B4BYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:clstn2
gene id: 42514:clstn2
uniprot id: A0A3B4D2N2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108430007
gene id: 42514:LOC108430007
uniprot id: A0A3B4CMA5
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:LOC108442564
gene id: 42514:LOC108442564
uniprot id: A0A3B4BSU1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108435155
gene id: 42514:LOC108435155
uniprot id: A0A3B4CMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

42514:dlgap1b
gene id: 42514:dlgap1b
uniprot id: A0A3B4D9U5
uniprot id: A0A3B4DDI6
names: Similarity
messages: Belongs to the SAPAP family.

42514:smad5
gene id: 42514:smad5
uniprot id: A0A3B4D5B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:tspan3b
gene id: 42514:tspan3b
uniprot id: A0A3B4CA14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:ndufc2
gene id: 42514:ndufc2
uniprot id: A0A3B4DR53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane

42514:LOC108440608
gene id: 42514:LOC108440608
uniprot id: A0A3B4CV87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:cltcb
gene id: 42514:cltcb
uniprot id: A0A3B4D4U2
uniprot id: A0A3B4EGZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

42514:tnfsf10l
gene id: 42514:tnfsf10l
uniprot id: A0A3B4D7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

42514:LOC108423609
gene id: 42514:LOC108423609
uniprot id: A0A3B4DIA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

42514:nme3
gene id: 42514:nme3
uniprot id: A0A3B4C6H2
names: Similarity
messages: Belongs to the NDK family.

42514:zranb1b
gene id: 42514:zranb1b
uniprot id: A0A3B4BUX6
names: Similarity
messages: Belongs to the peptidase C64 family.

42514:LOC108435180
gene id: 42514:LOC108435180
uniprot id: A0A3B4E6S3
names: Similarity
messages: Belongs to the BZW family.

42514:nfs1
gene id: 42514:nfs1
uniprot id: A0A3B4DIM2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

42514:napsa
gene id: 42514:napsa
uniprot id: A0A3B4CLV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

42514:mapkap1
gene id: 42514:mapkap1
uniprot id: A0A3B4CYG3
uniprot id: A0A3B4CZ52
names: Similarity
messages: Belongs to the SIN1 family.

42514:polr3h
gene id: 42514:polr3h
uniprot id: A0A3B4C956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

42514:epn2
gene id: 42514:epn2
uniprot id: A0A3B4D147
names: Similarity
messages: Belongs to the epsin family.

42514:prkg3
gene id: 42514:prkg3
uniprot id: A0A3B4E7X9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

42514:LOC108442814
gene id: 42514:LOC108442814
uniprot id: A0A3B4D824
names: Similarity
messages: Belongs to the cornifelin family.

42514:LOC108439344
gene id: 42514:LOC108439344
uniprot id: A0A3B4EL70
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:sec24d
gene id: 42514:sec24d
uniprot id: A0A3B4DR03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:tgfa
gene id: 42514:tgfa
uniprot id: A0A3B4E493
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108436230
gene id: 42514:LOC108436230
uniprot id: A0A3B4CKS8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

42514:LOC108412090
gene id: 42514:LOC108412090
uniprot id: A0A3B4CYV1
uniprot id: A0A3B4EB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:myclb
gene id: 42514:myclb
uniprot id: A0A3B4DMS3
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

42514:dhrs3b
gene id: 42514:dhrs3b
uniprot id: A0A3B4E9U4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:rrp7a
gene id: 42514:rrp7a
uniprot id: A0A3B4DW14
names: Similarity
messages: Belongs to the RRP7 family.

42514:LOC108436390
gene id: 42514:LOC108436390
uniprot id: A0A3B4DSH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:ddx41
gene id: 42514:ddx41
uniprot id: A0A3B4DU66
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

42514:bag6l
gene id: 42514:bag6l
uniprot id: A0A3B4DHU8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
messages: extracellular exosome

42514:rrs1
gene id: 42514:rrs1
uniprot id: A0A3B4CWB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

42514:pdpk1a
gene id: 42514:pdpk1a
uniprot id: A0A3B4DPU2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

42514:map3k10
gene id: 42514:map3k10
uniprot id: A0A3B4CRQ1
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

42514:hoxd10a
gene id: 42514:hoxd10a
uniprot id: A0A3B4ECD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:clip1a
gene id: 42514:clip1a
uniprot id: A0A3B4BW98
names: Subcellular Location Annotation
messages: cytoskeleton

42514:atp2b4
gene id: 42514:atp2b4
uniprot id: A0A3B4C2C4
uniprot id: A0A3B4C2T6
uniprot id: A0A3B4C578
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:extl3
gene id: 42514:extl3
uniprot id: A0A3B4C379
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

42514:zgc:172145
gene id: 42514:zgc:172145
uniprot id: A0A3B4DDM3
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

42514:tmem182b
gene id: 42514:tmem182b
uniprot id: A0A3B4CSG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

42514:LOC108410946
gene id: 42514:LOC108410946
uniprot id: A0A3B4D4F5
uniprot id: A0A3B4D7V2
names: Similarity
messages: Belongs to the MHC class I family.

42514:ercc2
gene id: 42514:ercc2
uniprot id: A0A3B4DQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

42514:med10
gene id: 42514:med10
uniprot id: A0A3B4D5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:kdm5a
gene id: 42514:kdm5a
uniprot id: A0A3B4DFF9
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

42514:sh3rf1
gene id: 42514:sh3rf1
uniprot id: A0A3B4CD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

42514:cdc34a
gene id: 42514:cdc34a
uniprot id: A0A3B4CMD4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:acsf3
gene id: 42514:acsf3
uniprot id: A0A3B4DVN8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:hyal6
gene id: 42514:hyal6
uniprot id: A0A3B4CH52
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

42514:dpf2l
gene id: 42514:dpf2l
uniprot id: A0A3B4D2H5
names: Similarity
messages: Belongs to the requiem/DPF family.

42514:sult1st5
gene id: 42514:sult1st5
uniprot id: A0A3B4E7Z1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:si:ch211-113g11.6
gene id: 42514:si:ch211-113g11.6
uniprot id: A0A3B4C5P6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:elavl3
gene id: 42514:elavl3
uniprot id: A0A3B4EAN4
names: Similarity
messages: Belongs to the RRM elav family.

42514:slc45a1
gene id: 42514:slc45a1
uniprot id: A0A3B4CCV8
names: Subcellular Location Annotation
messages: Membrane

42514:leap2
gene id: 42514:leap2
uniprot id: A0A3B4E605
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

42514:tspan14
gene id: 42514:tspan14
uniprot id: A0A3B4EIU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:ids
gene id: 42514:ids
uniprot id: A0A3B4D4I0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:slc25a19
gene id: 42514:slc25a19
uniprot id: A0A3B4CNL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:acvr2aa
gene id: 42514:acvr2aa
uniprot id: A0A3B4DQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:cylda
gene id: 42514:cylda
uniprot id: A0A3B4D2J9
uniprot id: A0A3B4EGI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

42514:LOC108423898
gene id: 42514:LOC108423898
uniprot id: A0A3B4CHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Membrane

42514:cdr2l
gene id: 42514:cdr2l
uniprot id: A0A3B4DVN0
names: Similarity
messages: Belongs to the CDR2 family.

42514:LOC108442282
gene id: 42514:LOC108442282
uniprot id: A0A3B4EC08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

42514:marf1
gene id: 42514:marf1
uniprot id: A0A3B4EN71
names: Subcellular Location Annotation
messages: Peroxisome

42514:ptges3l
gene id: 42514:ptges3l
uniprot id: A0A3B4DI52
names: Similarity
messages: Belongs to the p23/wos2 family.

42514:sec22a
gene id: 42514:sec22a
uniprot id: A0A3B4EJ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

42514:fars2
gene id: 42514:fars2
uniprot id: A0A3B4BMM2
uniprot id: A0A3B4DJU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

42514:LOC108435911
gene id: 42514:LOC108435911
uniprot id: A0A3B4C564
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:zgc:56095
gene id: 42514:zgc:56095
uniprot id: A0A3B4D7V7
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

42514:rad18
gene id: 42514:rad18
uniprot id: A0A3B4CEX8
uniprot id: A0A3B4E3G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD18 family.
messages: Nucleus

42514:galr1a
gene id: 42514:galr1a
uniprot id: A0A3B4CHM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:tcta
gene id: 42514:tcta
uniprot id: A0A3B4BMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: Membrane

42514:ccng1
gene id: 42514:ccng1
uniprot id: A0A3B4D0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

42514:tecrb
gene id: 42514:tecrb
uniprot id: A0A3B4D688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108411237
gene id: 42514:LOC108411237
uniprot id: A0A3B4C8X7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:ano2b
gene id: 42514:ano2b
uniprot id: A0A3B4DD20
uniprot id: A0A3B4DFN8
uniprot id: A0A3B4DFT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108431517
gene id: 42514:LOC108431517
uniprot id: A0A3B4BS08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

42514:camk2n1b
gene id: 42514:camk2n1b
uniprot id: A0A3B4CXX2
names: Similarity
messages: Belongs to the CAMK2N family.

42514:lpar2a
gene id: 42514:lpar2a
uniprot id: A0A3B4CHN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

42514:spc25
gene id: 42514:spc25
uniprot id: A0A3B4D0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

42514:htra1b
gene id: 42514:htra1b
uniprot id: A0A3B4ELA8
names: Similarity
messages: Belongs to the peptidase S1C family.

42514:anxa4
gene id: 42514:anxa4
uniprot id: A0A3B4E4P8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

42514:opa1
gene id: 42514:opa1
uniprot id: A0A3B4DSD1
uniprot id: A0A3B4DTM0
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

42514:nrp2b
gene id: 42514:nrp2b
uniprot id: A0A3B4C1W9
uniprot id: A0A3B4DSS4
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tgm2b
gene id: 42514:tgm2b
uniprot id: A0A3B4EMQ5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

42514:itpk1a
gene id: 42514:itpk1a
uniprot id: A0A3B4BU37
names: Similarity
messages: Belongs to the ITPK1 family.

42514:chst2a
gene id: 42514:chst2a
uniprot id: A0A3B4CIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:cks1b
gene id: 42514:cks1b
uniprot id: A0A3B4DN58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

42514:cryba1b
gene id: 42514:cryba1b
uniprot id: A0A3B4E102
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:LOC108434972
gene id: 42514:LOC108434972
uniprot id: A0A3B4DDL2
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

42514:dusp6
gene id: 42514:dusp6
uniprot id: A0A3B4D664
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

42514:enpp6
gene id: 42514:enpp6
uniprot id: A0A3B4EIE3
names: Similarity
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

42514:LOC108412396
gene id: 42514:LOC108412396
uniprot id: A0A3B4DTK9
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:grm4
gene id: 42514:grm4
uniprot id: A0A3B4DPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

42514:chmp5a
gene id: 42514:chmp5a
uniprot id: A0A3B4CQQ9
names: Similarity
messages: Belongs to the SNF7 family.

42514:LOC108413265
gene id: 42514:LOC108413265
uniprot id: A0A3B4EP29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

42514:cdnf
gene id: 42514:cdnf
uniprot id: A0A3B4BVM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

42514:spata6
gene id: 42514:spata6
uniprot id: A0A3B4CLZ4
names: Similarity
messages: Belongs to the SPATA6 family.

42514:mki67
gene id: 42514:mki67
uniprot id: A0A3B4C5F1
names: Subcellular Location Annotation
messages: Nucleus

42514:sparc
gene id: 42514:sparc
uniprot id: A0A3B4D543
names: Similarity
messages: Belongs to the SPARC family.

42514:LOC108439621
gene id: 42514:LOC108439621
uniprot id: A0A3B4CIR8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108426519
gene id: 42514:LOC108426519
uniprot id: A0A3B4D9I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

42514:serp2
gene id: 42514:serp2
uniprot id: A0A3B4CL15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

42514:dedd
gene id: 42514:dedd
uniprot id: A0A3B4EB37
names: Subcellular Location Annotation
messages: nucleolus

42514:pold2
gene id: 42514:pold2
uniprot id: A0A3B4EE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Nucleus

42514:med16
gene id: 42514:med16
uniprot id: A0A3B4D5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:dis3l
gene id: 42514:dis3l
uniprot id: A0A3B4DYY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family.
messages: Cytoplasm

42514:mtr
gene id: 42514:mtr
uniprot id: A0A3B4E701
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

42514:pkn2
gene id: 42514:pkn2
uniprot id: A0A3B4BXY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

42514:june
gene id: 42514:june
uniprot id: A0A3B4CAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

42514:smarcad1b
gene id: 42514:smarcad1b
uniprot id: A0A3B4BYU4
names: Subcellular Location Annotation
messages: Chromosome

42514:LOC108426860
gene id: 42514:LOC108426860
uniprot id: A0A3B4C658
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

42514:LOC108413075
gene id: 42514:LOC108413075
uniprot id: A0A3B4C034
uniprot id: A0A3B4DRS8
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108420326
gene id: 42514:LOC108420326
uniprot id: A0A3B4CJF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:orai1b
gene id: 42514:orai1b
uniprot id: A0A3B4CJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

42514:fam20b
gene id: 42514:fam20b
uniprot id: A0A3B4BS21
names: Similarity
messages: Belongs to the FAM20 family.

42514:elapor2a
gene id: 42514:elapor2a
uniprot id: A0A3B4EDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

42514:igf2b
gene id: 42514:igf2b
uniprot id: A0A3B4DM38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

42514:map2k2a
gene id: 42514:map2k2a
uniprot id: A0A3B4E4L6
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:ephb2a
gene id: 42514:ephb2a
uniprot id: A0A3B4E8J6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:tnfsf10
gene id: 42514:tnfsf10
uniprot id: A0A3B4EPK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

42514:agpat9l
gene id: 42514:agpat9l
uniprot id: A0A3B4C159
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:LOC108431241
gene id: 42514:LOC108431241
uniprot id: A0A3B4BSA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:hps5
gene id: 42514:hps5
uniprot id: A0A3B4EFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

42514:zgc:114130
gene id: 42514:zgc:114130
uniprot id: A0A3B4CZR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:otud5a
gene id: 42514:otud5a
uniprot id: A0A3B4EI93
names: Similarity
messages: Belongs to the peptidase C85 family.

42514:specc1la
gene id: 42514:specc1la
uniprot id: A0A3B4DQM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytospin-A family.
messages: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.
messages: May interact with both microtubules and actin cytoskeleton.
messages: cytoskeleton
messages: gap junction
messages: spindle

42514:mmp21
gene id: 42514:mmp21
uniprot id: A0A3B4DFU2
names: Similarity
messages: Belongs to the peptidase M10A family.

42514:ttr
gene id: 42514:ttr
uniprot id: A0A3B4ENL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

42514:slc25a36a
gene id: 42514:slc25a36a
uniprot id: A0A3B4CVF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:pmpcb
gene id: 42514:pmpcb
uniprot id: A0A3B4CHQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

42514:snrpd1
gene id: 42514:snrpd1
uniprot id: A0A3B4CL64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

42514:LOC108440368
gene id: 42514:LOC108440368
uniprot id: A0A3B4DIF4
names: Subcellular Location Annotation
messages: Membrane

42514:tlcd3ba
gene id: 42514:tlcd3ba
uniprot id: A0A3B4CQ48
names: Subcellular Location Annotation
messages: Membrane

42514:znf706
gene id: 42514:znf706
uniprot id: A0A3B4EJ84
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:lrrc51
gene id: 42514:lrrc51
uniprot id: A0A3B4DL11
names: Subcellular Location Annotation
messages: Cytoplasm

42514:tax1bp3
gene id: 42514:tax1bp3
uniprot id: A0A3B4EGT1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

42514:fignl1
gene id: 42514:fignl1
uniprot id: A0A3B4DF19
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:ssbp3b
gene id: 42514:ssbp3b
uniprot id: A0A3B4EFN4
names: Subcellular Location Annotation
messages: Nucleus

42514:cdkn3
gene id: 42514:cdkn3
uniprot id: A0A3B4CVT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

42514:pdgfd
gene id: 42514:pdgfd
uniprot id: A0A3B4DIQ1
names: Caution
names: Subunit
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:nrxn3b
gene id: 42514:nrxn3b
uniprot id: A0A3B4EIN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108440498
gene id: 42514:LOC108440498
uniprot id: A0A3B4D938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:LOC108438552
gene id: 42514:LOC108438552
uniprot id: A0A3B4CJU1
names: Similarity
messages: Belongs to the PROTOR family.

42514:lpcat4
gene id: 42514:lpcat4
uniprot id: A0A3B4EBJ5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:ahsa1a
gene id: 42514:ahsa1a
uniprot id: A0A3B4DKJ2
names: Similarity
messages: Belongs to the AHA1 family.

42514:LOC108415358
gene id: 42514:LOC108415358
uniprot id: A0A3B4E958
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

42514:sema3aa
gene id: 42514:sema3aa
uniprot id: A0A3B4DGC4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:slu7
gene id: 42514:slu7
uniprot id: A0A3B4DFB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

42514:cdh11
gene id: 42514:cdh11
uniprot id: A0A3B4DGX0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:slc35f6
gene id: 42514:slc35f6
uniprot id: A0A3B4C899
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

42514:rpl31
gene id: 42514:rpl31
uniprot id: A0A3B4E7Z7
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

42514:cenph
gene id: 42514:cenph
uniprot id: A0A3B4CRC7
uniprot id: A0A3B4E7M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

42514:mitfa
gene id: 42514:mitfa
uniprot id: A0A3B4BS06
uniprot id: A0A3B4DJ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

42514:zgc:114123
gene id: 42514:zgc:114123
uniprot id: A0A3B4EDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

42514:dkk1b
gene id: 42514:dkk1b
uniprot id: A0A3B4BQH4
names: Similarity
messages: Belongs to the dickkopf family.

42514:LOC108441066
gene id: 42514:LOC108441066
uniprot id: A0A3B4EHY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

42514:LOC108426776
gene id: 42514:LOC108426776
uniprot id: A0A3B4DYQ0
names: Subcellular Location Annotation
messages: Membrane

42514:slc26a10
gene id: 42514:slc26a10
uniprot id: A0A3B4CZS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

42514:oxct1a
gene id: 42514:oxct1a
uniprot id: A0A3B4BP26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

42514:LOC108424028
gene id: 42514:LOC108424028
uniprot id: A0A3B4DLZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:atp2a2a
gene id: 42514:atp2a2a
uniprot id: A0A3B4D2X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

42514:rorca
gene id: 42514:rorca
uniprot id: A0A3B4C2F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:LOC108412047
gene id: 42514:LOC108412047
uniprot id: A0A3B4DCH5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

42514:paqr8
gene id: 42514:paqr8
uniprot id: A0A3B4EQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:megf6a
gene id: 42514:megf6a
uniprot id: A0A3B4CJW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:kcnk6
gene id: 42514:kcnk6
uniprot id: A0A3B4C8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

42514:homeza
gene id: 42514:homeza
uniprot id: A0A3B4CW66
names: Subcellular Location Annotation
messages: Nucleus

42514:isl2b
gene id: 42514:isl2b
uniprot id: A0A3B4DYU5
names: Subcellular Location Annotation
messages: Nucleus

42514:smx5
gene id: 42514:smx5
uniprot id: A0A3B4DCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

42514:prox3
gene id: 42514:prox3
uniprot id: A0A3B4EA20
names: Subcellular Location Annotation
messages: Nucleus

42514:nav2b
gene id: 42514:nav2b
uniprot id: A0A3B4EFU5
names: Similarity
messages: Belongs to the Nav/unc-53 family.

42514:adam17a
gene id: 42514:adam17a
uniprot id: A0A3B4CJR4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108414724
gene id: 42514:LOC108414724
uniprot id: A0A3B4CIA5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:polr1e
gene id: 42514:polr1e
uniprot id: A0A3B4BR86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

42514:pam
gene id: 42514:pam
uniprot id: A0A3B4CRU0
uniprot id: A0A3B4CU02
names: Similarity
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.

42514:zdhhc3b
gene id: 42514:zdhhc3b
uniprot id: A0A3B4E4B8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:emp3b
gene id: 42514:emp3b
uniprot id: A0A3B4DTD0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:dlg3
gene id: 42514:dlg3
uniprot id: A0A3B4CKY2
names: Similarity
messages: Belongs to the MAGUK family.

42514:chrna11
gene id: 42514:chrna11
uniprot id: A0A3B4E480
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:vrk1
gene id: 42514:vrk1
uniprot id: A0A3B4DL58
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108443058
gene id: 42514:LOC108443058
uniprot id: A0A3B4C8Q7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:smarca2
gene id: 42514:smarca2
uniprot id: A0A3B4DWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

42514:parvaa
gene id: 42514:parvaa
uniprot id: A0A3B4BZK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

42514:cux2b
gene id: 42514:cux2b
uniprot id: A0A3B4DJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

42514:LOC108438397
gene id: 42514:LOC108438397
uniprot id: A0A3B4E7W5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:epha7
gene id: 42514:epha7
uniprot id: A0A3B4C7J5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:LOC108424627
gene id: 42514:LOC108424627
uniprot id: A0A3B4BQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:rtca
gene id: 42514:rtca
uniprot id: A0A3B4CXU9
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

42514:dennd10
gene id: 42514:dennd10
uniprot id: A0A3B4C1S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

42514:tsg101a
gene id: 42514:tsg101a
uniprot id: A0A3B4DZK0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

42514:ppib
gene id: 42514:ppib
uniprot id: A0A3B4DBR6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:LOC108442714
gene id: 42514:LOC108442714
uniprot id: A0A3B4DHT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Cell projection
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

42514:gls2a
gene id: 42514:gls2a
uniprot id: A0A3B4D1I7
names: Similarity
messages: Belongs to the glutaminase family.

42514:LOC108424757
gene id: 42514:LOC108424757
uniprot id: A0A3B4ERF9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108439786
gene id: 42514:LOC108439786
uniprot id: A0A3B4DP49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:LOC108432998
gene id: 42514:LOC108432998
uniprot id: A0A3B4CHP5
names: Similarity
messages: Belongs to the WSCD family.

42514:zdhhc3a
gene id: 42514:zdhhc3a
uniprot id: A0A3B4C206
uniprot id: A0A3B4DNT9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:dhx29
gene id: 42514:dhx29
uniprot id: A0A3B4DL91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

42514:tpd52l2b
gene id: 42514:tpd52l2b
uniprot id: A0A3B4CDT1
uniprot id: A0A3B4E1A4
names: Similarity
messages: Belongs to the TPD52 family.

42514:g6pc3
gene id: 42514:g6pc3
uniprot id: A0A3B4EM66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

42514:LOC108440005
gene id: 42514:LOC108440005
uniprot id: A0A3B4D021
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:prkcaa
gene id: 42514:prkcaa
uniprot id: A0A3B4EPR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

42514:nkiras2
gene id: 42514:nkiras2
uniprot id: A0A3B4DDR3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

42514:atp10a
gene id: 42514:atp10a
uniprot id: A0A3B4DVS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:prrt1b
gene id: 42514:prrt1b
uniprot id: A0A3B4DIX3
names: Similarity
messages: Belongs to the CD225/Dispanin family.

42514:si:ch1073-174d20.2
gene id: 42514:si:ch1073-174d20.2
uniprot id: A0A3B4CH69
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

42514:triob
gene id: 42514:triob
uniprot id: A0A3B4C5Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

42514:gpd2
gene id: 42514:gpd2
uniprot id: A0A3B4CG50
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

42514:ube4a
gene id: 42514:ube4a
uniprot id: A0A3B4EIC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

42514:fgf14
gene id: 42514:fgf14
uniprot id: A0A3B4C628
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:nelfe
gene id: 42514:nelfe
uniprot id: A0A3B4C134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus

42514:lamtor4
gene id: 42514:lamtor4
uniprot id: A0A3B4DNE1
names: Similarity
messages: Belongs to the LAMTOR4 family.

42514:si:dkeyp-75b4.8
gene id: 42514:si:dkeyp-75b4.8
uniprot id: A0A3B4DUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

42514:adipor1b
gene id: 42514:adipor1b
uniprot id: A0A3B4CMW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:cplx4a
gene id: 42514:cplx4a
uniprot id: A0A3B4EES7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

42514:rida
gene id: 42514:rida
uniprot id: A0A3B4C1S0
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.

42514:LOC108415751
gene id: 42514:LOC108415751
uniprot id: A0A3B4EHE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
messages: Cytoplasm
messages: Melanosome
messages: Nucleus
messages: lamellipodium
messages: ruffle

42514:LOC108428329
gene id: 42514:LOC108428329
uniprot id: A0A3B4EA18
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:hoxc12a
gene id: 42514:hoxc12a
uniprot id: A0A3B4EB15
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108412783
gene id: 42514:LOC108412783
uniprot id: A0A3B4CZ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

42514:c4h8orf82
gene id: 42514:c4h8orf82
uniprot id: A0A3B4DJ28
names: Similarity
messages: Belongs to the UPF0598 family.

42514:dtnbp1a
gene id: 42514:dtnbp1a
uniprot id: A0A3B4BSG9
uniprot id: A0A3B4DMT4
names: Similarity
messages: Belongs to the dysbindin family.

42514:zeb2b
gene id: 42514:zeb2b
uniprot id: A0A3B4EF87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.
messages: Nucleus

42514:LOC108410948
gene id: 42514:LOC108410948
uniprot id: A0A3B4EJH3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:fam32a
gene id: 42514:fam32a
uniprot id: A0A3B4BJU7
names: Similarity
messages: Belongs to the FAM32 family.

42514:grk3
gene id: 42514:grk3
uniprot id: A0A3B4BSP0
uniprot id: A0A3B4BW62
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:ldhd
gene id: 42514:ldhd
uniprot id: A0A3B4CYU9
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

42514:tsen2
gene id: 42514:tsen2
uniprot id: A0A3B4BSP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

42514:ppp1r12c
gene id: 42514:ppp1r12c
uniprot id: A0A3B4DG72
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

42514:aldh7a1
gene id: 42514:aldh7a1
uniprot id: A0A3B4DK63
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

42514:capza1b
gene id: 42514:capza1b
uniprot id: A0A3B4C5M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

42514:cog7
gene id: 42514:cog7
uniprot id: A0A3B4DX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:eomesa
gene id: 42514:eomesa
uniprot id: A0A3B4C6Y0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:oclna
gene id: 42514:oclna
uniprot id: A0A3B4DTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:LOC108438074
gene id: 42514:LOC108438074
uniprot id: A0A3B4BXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane

42514:sugt1
gene id: 42514:sugt1
uniprot id: A0A3B4CGY0
names: Similarity
messages: Belongs to the SGT1 family.

42514:gabra2a
gene id: 42514:gabra2a
uniprot id: A0A3B4DXA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

42514:dyrk2
gene id: 42514:dyrk2
uniprot id: A0A3B4DBG8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:ganc
gene id: 42514:ganc
uniprot id: A0A3B4E3G9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

42514:jph3
gene id: 42514:jph3
uniprot id: A0A3B4DL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:gle1
gene id: 42514:gle1
uniprot id: A0A3B4DJC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

42514:ca10a
gene id: 42514:ca10a
uniprot id: A0A3B4C080
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.

42514:rps27a
gene id: 42514:rps27a
uniprot id: A0A3B4CB12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Ribosomal protein S27a is part of the 40S ribosomal subunit.

42514:LOC108443576
gene id: 42514:LOC108443576
uniprot id: A0A3B4ES67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

42514:hdac3
gene id: 42514:hdac3
uniprot id: A0A3B4D146
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

42514:LOC108426645
gene id: 42514:LOC108426645
uniprot id: A0A3B4D947
names: Similarity
messages: Belongs to the mab-21 family.

42514:LOC108440225
gene id: 42514:LOC108440225
uniprot id: A0A3B4C6Z7
names: Similarity
messages: Belongs to the globin family.

42514:LOC108426655
gene id: 42514:LOC108426655
uniprot id: A0A3B4D7K9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

42514:eif2b2
gene id: 42514:eif2b2
uniprot id: A0A3B4CV64
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

42514:LOC108437388
gene id: 42514:LOC108437388
uniprot id: A0A3B4EAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:plpbp
gene id: 42514:plpbp
uniprot id: A0A3B4D0E5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

42514:kita
gene id: 42514:kita
uniprot id: A0A3B4DN21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:oat
gene id: 42514:oat
uniprot id: A0A3B4ECB7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

42514:slc35f4
gene id: 42514:slc35f4
uniprot id: A0A3B4CID0
uniprot id: A0A3B4E4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

42514:ing5b
gene id: 42514:ing5b
uniprot id: A0A3B4DXY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

42514:LOC108414617
gene id: 42514:LOC108414617
uniprot id: A0A3B4CSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:adprhl1
gene id: 42514:adprhl1
uniprot id: A0A3B4DR55
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

42514:r3hdml
gene id: 42514:r3hdml
uniprot id: A0A3B4CSJ9
names: Similarity
messages: Belongs to the CRISP family.

42514:cpne5b
gene id: 42514:cpne5b
uniprot id: A0A3B4C1G0
uniprot id: A0A3B4DU64
names: Similarity
messages: Belongs to the copine family.

42514:pelp1
gene id: 42514:pelp1
uniprot id: A0A3B4CPL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Cytoplasm
messages: Nucleus

42514:cd81a
gene id: 42514:cd81a
uniprot id: A0A3B4DXN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:LOC108438687
gene id: 42514:LOC108438687
uniprot id: A0A3B4DVK4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:pou2f1a
gene id: 42514:pou2f1a
uniprot id: A0A3B4DRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

42514:LOC108433269
gene id: 42514:LOC108433269
uniprot id: A0A3B4DF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:sugp1
gene id: 42514:sugp1
uniprot id: A0A3B4EIR1
names: Subcellular Location Annotation
messages: Nucleus

42514:si:ch211-63o20.7
gene id: 42514:si:ch211-63o20.7
uniprot id: A0A3B4DG25
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:anxa5a
gene id: 42514:anxa5a
uniprot id: A0A3B4EK18
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

42514:LOC108441595
gene id: 42514:LOC108441595
uniprot id: A0A3B4DFT7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

42514:ndst2b
gene id: 42514:ndst2b
uniprot id: A0A3B4ECK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

42514:amh
gene id: 42514:amh
uniprot id: A0A3B4DF01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

42514:rdh10b
gene id: 42514:rdh10b
uniprot id: A0A3B4E490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

42514:nmt1a
gene id: 42514:nmt1a
uniprot id: A0A3B4DKX9
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

42514:camkk1b
gene id: 42514:camkk1b
uniprot id: A0A3B4BVR3
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:cav2
gene id: 42514:cav2
uniprot id: A0A3B4ELA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

42514:LOC108435978
gene id: 42514:LOC108435978
uniprot id: A0A3B4C076
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:epc1b
gene id: 42514:epc1b
uniprot id: A0A3B4E113
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

42514:ccnl1a
gene id: 42514:ccnl1a
uniprot id: A0A3B4DZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Nucleus speckle
messages: nucleoplasm

42514:zw10
gene id: 42514:zw10
uniprot id: A0A3B4CBX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZW10 family.
messages: kinetochore

42514:mdm1
gene id: 42514:mdm1
uniprot id: A0A3B4EN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

42514:xkr8.3
gene id: 42514:xkr8.3
uniprot id: A0A3B4E0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:poglut2
gene id: 42514:poglut2
uniprot id: A0A3B4D6N3
names: Similarity
messages: Belongs to the KDELC family.

42514:unc45a
gene id: 42514:unc45a
uniprot id: A0A3B4DGF8
names: Subcellular Location Annotation
messages: perinuclear region

42514:ppp2caa
gene id: 42514:ppp2caa
uniprot id: A0A3B4DQ24
names: Similarity
messages: Belongs to the PPP phosphatase family.

42514:fes
gene id: 42514:fes
uniprot id: A0A3B4CAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

42514:tmem150ab
gene id: 42514:tmem150ab
uniprot id: A0A3B4BQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRAM/TMEM150 family.
messages: Cell membrane
messages: Membrane

42514:LOC108434733
gene id: 42514:LOC108434733
uniprot id: A0A3B4CHJ8
uniprot id: A0A3B4CJW7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:LOC108439717
gene id: 42514:LOC108439717
uniprot id: A0A3B4DVE3
names: Similarity
messages: Belongs to the BLCAP family.

42514:trpm2
gene id: 42514:trpm2
uniprot id: A0A3B4DWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

42514:cxcr2
gene id: 42514:cxcr2
uniprot id: A0A3B4BQ64
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:gpr157
gene id: 42514:gpr157
uniprot id: A0A3B4E9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 5 family.
messages: Membrane

42514:dus4l
gene id: 42514:dus4l
uniprot id: A0A3B4CX09
uniprot id: A0A3B4ECE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

42514:dyrk1aa
gene id: 42514:dyrk1aa
uniprot id: A0A3B4C0P6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:apoea
gene id: 42514:apoea
uniprot id: A0A3B4BUS2
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

42514:ndufb7
gene id: 42514:ndufb7
uniprot id: A0A3B4D5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

42514:maml3
gene id: 42514:maml3
uniprot id: A0A3B4CCR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

42514:sult4a1
gene id: 42514:sult4a1
uniprot id: A0A3B4BY85
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:rps3
gene id: 42514:rps3
uniprot id: A0A3B4E7S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: nucleolus
messages: spindle

42514:gamt
gene id: 42514:gamt
uniprot id: A0A3B4DSA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.
messages: Monomer.

42514:ptpn6
gene id: 42514:ptpn6
uniprot id: A0A3B4DRT6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.

42514:ing1
gene id: 42514:ing1
uniprot id: A0A3B4CUJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

42514:tmbim4
gene id: 42514:tmbim4
uniprot id: A0A3B4BS35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

42514:fam13c
gene id: 42514:fam13c
uniprot id: A0A3B4E774
names: Similarity
messages: Belongs to the FAM13 family.

42514:spcs3
gene id: 42514:spcs3
uniprot id: A0A3B4DW95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

42514:tmem176
gene id: 42514:tmem176
uniprot id: A0A3B4CIE8
names: Similarity
messages: Belongs to the MS4A family.

42514:sec63
gene id: 42514:sec63
uniprot id: A0A3B4BX95
uniprot id: A0A3B4DK88
names: Subcellular Location Annotation
messages: Membrane

42514:bcan
gene id: 42514:bcan
uniprot id: A0A3B4DUK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108434740
gene id: 42514:LOC108434740
uniprot id: A0A3B4CF57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:wdr18
gene id: 42514:wdr18
uniprot id: A0A3B4D676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Dynein axonemal particle
messages: nucleolus
messages: nucleoplasm

42514:kif5ab
gene id: 42514:kif5ab
uniprot id: A0A3B4CH11
uniprot id: A0A3B4E4S8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:frem1a
gene id: 42514:frem1a
uniprot id: A0A3B4BXE3
names: Similarity
messages: Belongs to the FRAS1 family.

42514:tmed10
gene id: 42514:tmed10
uniprot id: A0A3B4EAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:pnrc2
gene id: 42514:pnrc2
uniprot id: A0A3B4E7R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

42514:ldlrad2
gene id: 42514:ldlrad2
uniprot id: A0A3B4CI26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:clcf1
gene id: 42514:clcf1
uniprot id: A0A3B4EL32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

42514:ube2g1b
gene id: 42514:ube2g1b
uniprot id: A0A3B4E341
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:mturn
gene id: 42514:mturn
uniprot id: A0A3B4CMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTURN family.
messages: Cytoplasm

42514:ndufaf1
gene id: 42514:ndufaf1
uniprot id: A0A3B4C7Y9
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

42514:shhb
gene id: 42514:shhb
uniprot id: A0A3B4CS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

42514:zgc:162200
gene id: 42514:zgc:162200
uniprot id: A0A3B4BMM6
names: Similarity
messages: Belongs to the BicD family.

42514:foxq2
gene id: 42514:foxq2
uniprot id: A0A3B4DFV5
names: Subcellular Location Annotation
messages: Nucleus

42514:pdia6
gene id: 42514:pdia6
uniprot id: A0A3B4CT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

42514:tpm4b
gene id: 42514:tpm4b
uniprot id: A0A3B4D2M7
uniprot id: A0A3B4D567
uniprot id: A0A3B4EH76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

42514:cep44
gene id: 42514:cep44
uniprot id: A0A3B4CM09
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

42514:si:ch211-286o17.1
gene id: 42514:si:ch211-286o17.1
uniprot id: A0A3B4DQV3
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108423593
gene id: 42514:LOC108423593
uniprot id: A0A3B4D7A8
uniprot id: A0A3B4D7B8
names: Subcellular Location Annotation
messages: Nucleus

42514:alpl
gene id: 42514:alpl
uniprot id: A0A3B4CSJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

42514:b3galt1b
gene id: 42514:b3galt1b
uniprot id: A0A3B4CXW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:tyrp1b
gene id: 42514:tyrp1b
uniprot id: A0A3B4BND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

42514:LOC108412023
gene id: 42514:LOC108412023
uniprot id: A0A3B4DDU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

42514:slc1a1
gene id: 42514:slc1a1
uniprot id: A0A3B4C1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:nhp2
gene id: 42514:nhp2
uniprot id: A0A3B4C8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

42514:chmp1a
gene id: 42514:chmp1a
uniprot id: A0A3B4CLV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF7 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

42514:LOC108443054
gene id: 42514:LOC108443054
uniprot id: A0A3B4C722
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:kcnc1b
gene id: 42514:kcnc1b
uniprot id: A0A3B4BM53
uniprot id: A0A3B4BQ49
names: Subcellular Location Annotation
messages: Membrane

42514:st6gal2b
gene id: 42514:st6gal2b
uniprot id: A0A3B4BWL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:purg
gene id: 42514:purg
uniprot id: A0A3B4EGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

42514:wls
gene id: 42514:wls
uniprot id: A0A3B4DC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108411299
gene id: 42514:LOC108411299
uniprot id: A0A3B4BV84
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:sema4f
gene id: 42514:sema4f
uniprot id: A0A3B4BXF5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cdh26.1
gene id: 42514:cdh26.1
uniprot id: A0A3B4C2T5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:LOC108441156
gene id: 42514:LOC108441156
uniprot id: A0A3B4ECD9
names: Subcellular Location Annotation
messages: Membrane

42514:ddx20
gene id: 42514:ddx20
uniprot id: A0A3B4CM03
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:aif1l
gene id: 42514:aif1l
uniprot id: A0A3B4CP82
names: Subcellular Location Annotation
messages: ruffle membrane

42514:fxn
gene id: 42514:fxn
uniprot id: A0A3B4E7W7
names: Similarity
messages: Belongs to the frataxin family.

42514:tbccd1
gene id: 42514:tbccd1
uniprot id: A0A3B4D7X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

42514:arr3a
gene id: 42514:arr3a
uniprot id: A0A3B4ELA7
names: Function
names: Similarity
messages: Belongs to the arrestin family.
messages: May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.

42514:fabp7a
gene id: 42514:fabp7a
uniprot id: A0A3B4D120
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:LOC108430711
gene id: 42514:LOC108430711
uniprot id: A0A3B4E306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:cilp2
gene id: 42514:cilp2
uniprot id: A0A3B4CRX3
names: Subcellular Location Annotation
messages: extracellular matrix

42514:LOC108443952
gene id: 42514:LOC108443952
uniprot id: A0A3B4DAR5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108436296
gene id: 42514:LOC108436296
uniprot id: A0A3B4CBY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108442166
gene id: 42514:LOC108442166
uniprot id: A0A3B4D9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

42514:fam126a
gene id: 42514:fam126a
uniprot id: A0A3B4E6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

42514:kif11
gene id: 42514:kif11
uniprot id: A0A3B4DB64
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:si:dkey-28b4.8
gene id: 42514:si:dkey-28b4.8
uniprot id: A0A3B4E171
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

42514:ackr3b
gene id: 42514:ackr3b
uniprot id: A0A3B4BW51
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:cdx1a
gene id: 42514:cdx1a
uniprot id: A0A3B4C0V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

42514:mfsd8
gene id: 42514:mfsd8
uniprot id: A0A3B4BZJ0
names: Subcellular Location Annotation
messages: Membrane

42514:gorasp2
gene id: 42514:gorasp2
uniprot id: A0A3B4C094
names: Similarity
messages: Belongs to the GORASP family.

42514:c8a
gene id: 42514:c8a
uniprot id: A0A3B4BYU7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:rtraf
gene id: 42514:rtraf
uniprot id: A0A3B4DZE9
names: Similarity
messages: Belongs to the RTRAF family.

42514:gucy1a1
gene id: 42514:gucy1a1
uniprot id: A0A3B4DK59
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

42514:lyrm5a
gene id: 42514:lyrm5a
uniprot id: A0A3B4EQI5
names: Similarity
messages: Belongs to the complex I LYR family.

42514:zgc:153990
gene id: 42514:zgc:153990
uniprot id: A0A3B4D2R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

42514:dlx2b
gene id: 42514:dlx2b
uniprot id: A0A3B4BVE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

42514:aoc2
gene id: 42514:aoc2
uniprot id: A0A3B4C959
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

42514:coro1ca
gene id: 42514:coro1ca
uniprot id: A0A3B4DTX8
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:bco2a
gene id: 42514:bco2a
uniprot id: A0A3B4DTC2
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

42514:sypl2a
gene id: 42514:sypl2a
uniprot id: A0A3B4CIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

42514:gpr132a
gene id: 42514:gpr132a
uniprot id: A0A3B4CCK7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:f11r.1
gene id: 42514:f11r.1
uniprot id: A0A3B4DUA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:LOC108437214
gene id: 42514:LOC108437214
uniprot id: A0A3B4D6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:cacng4b
gene id: 42514:cacng4b
uniprot id: A0A3B4E457
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

42514:chst14
gene id: 42514:chst14
uniprot id: A0A3B4BWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:adgra3
gene id: 42514:adgra3
uniprot id: A0A3B4BWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

42514:pus3
gene id: 42514:pus3
uniprot id: A0A3B4E0H3
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

42514:rnd3a
gene id: 42514:rnd3a
uniprot id: A0A3B4C9Z6
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

42514:LOC108440716
gene id: 42514:LOC108440716
uniprot id: A0A3B4E4G0
names: Similarity
messages: Belongs to the MHC class I family.

42514:uba6
gene id: 42514:uba6
uniprot id: A0A3B4BXI0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

42514:tmem175
gene id: 42514:tmem175
uniprot id: A0A3B4CNY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

42514:srxn1
gene id: 42514:srxn1
uniprot id: A0A3B4E7R6
names: Similarity
messages: Belongs to the sulfiredoxin family.

42514:slc1a5
gene id: 42514:slc1a5
uniprot id: A0A3B4ECU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:LOC108440214
gene id: 42514:LOC108440214
uniprot id: A0A3B4C7B6
names: Similarity
messages: Belongs to the globin family.

42514:lamb4
gene id: 42514:lamb4
uniprot id: A0A3B4E3J2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

42514:LOC108432842
gene id: 42514:LOC108432842
uniprot id: A0A3B4D2Q6
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

42514:eif3m
gene id: 42514:eif3m
uniprot id: A0A3B4E8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

42514:zgc:154055
gene id: 42514:zgc:154055
uniprot id: A0A3B4D4C2
uniprot id: A0A3B4D630
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

42514:zgc:77439
gene id: 42514:zgc:77439
uniprot id: A0A3B4D8Q9
names: Similarity
messages: Belongs to the FMO family.

42514:gpn3
gene id: 42514:gpn3
uniprot id: A0A3B4CEN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

42514:tsc22d2
gene id: 42514:tsc22d2
uniprot id: A0A3B4CGW2
uniprot id: A0A3B4DZG4
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

42514:rbks
gene id: 42514:rbks
uniprot id: A0A3B4C070
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

42514:LOC108413418
gene id: 42514:LOC108413418
uniprot id: A0A3B4ECP1
names: Subcellular Location Annotation
messages: Nucleus

42514:sptbn1
gene id: 42514:sptbn1
uniprot id: A0A3B4BMZ0
uniprot id: A0A3B4BR89
names: Similarity
messages: Belongs to the spectrin family.

42514:LOC108415106
gene id: 42514:LOC108415106
uniprot id: A0A3B4EH29
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

42514:ccnd1
gene id: 42514:ccnd1
uniprot id: A0A3B4E9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

42514:tnpo3
gene id: 42514:tnpo3
uniprot id: A0A3B4BRE3
names: Subcellular Location Annotation
messages: Cytoplasm

42514:txnipb
gene id: 42514:txnipb
uniprot id: A0A3B4BSE5
names: Similarity
messages: Belongs to the arrestin family.

42514:plod1a
gene id: 42514:plod1a
uniprot id: A0A3B4DBN8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

42514:amer3
gene id: 42514:amer3
uniprot id: A0A3B4CRJ1
names: Similarity
messages: Belongs to the Amer family.

42514:insig2
gene id: 42514:insig2
uniprot id: A0A3B4EHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

42514:cdk14
gene id: 42514:cdk14
uniprot id: A0A3B4EA84
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:sh3bp5b
gene id: 42514:sh3bp5b
uniprot id: A0A3B4D1I9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

42514:LOC108415275
gene id: 42514:LOC108415275
uniprot id: A0A3B4CTM2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:rptor
gene id: 42514:rptor
uniprot id: A0A3B4D9T2
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

42514:foxh1
gene id: 42514:foxh1
uniprot id: A0A3B4DUF7
names: Subcellular Location Annotation
messages: Nucleus

42514:slc2a3a
gene id: 42514:slc2a3a
uniprot id: A0A3B4DCH0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:cpne3
gene id: 42514:cpne3
uniprot id: A0A3B4CY54
uniprot id: A0A3B4CZS3
names: Similarity
messages: Belongs to the copine family.

42514:LOC108439766
gene id: 42514:LOC108439766
uniprot id: A0A3B4BZF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:cnr1
gene id: 42514:cnr1
uniprot id: A0A3B4CC91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids. Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues. Signaling typically involves reduction in cyclic AMP.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

42514:sept2
gene id: 42514:sept2
uniprot id: A0A3B4C0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

42514:si:ch211-194m7.8
gene id: 42514:si:ch211-194m7.8
uniprot id: A0A3B4DPJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108428237
gene id: 42514:LOC108428237
uniprot id: A0A3B4CZL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

42514:kiaa1191
gene id: 42514:kiaa1191
uniprot id: A0A3B4DG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P33MONOX family.
messages: Cytoplasm

42514:amot
gene id: 42514:amot
uniprot id: A0A3B4CF87
names: Similarity
messages: Belongs to the angiomotin family.

42514:pax9
gene id: 42514:pax9
uniprot id: A0A3B4CEZ6
names: Subcellular Location Annotation
messages: Nucleus

42514:tyro3
gene id: 42514:tyro3
uniprot id: A0A3B4BTB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

42514:LOC108423976
gene id: 42514:LOC108423976
uniprot id: A0A3B4DS83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

42514:pigw
gene id: 42514:pigw
uniprot id: A0A3B4BUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

42514:shox2
gene id: 42514:shox2
uniprot id: A0A3B4DLH9
uniprot id: A0A3B4DLI4
names: Subcellular Location Annotation
messages: Nucleus

42514:fxr1
gene id: 42514:fxr1
uniprot id: A0A3B4CUS4
names: Similarity
messages: Belongs to the FMR1 family.

42514:smfn
gene id: 42514:smfn
uniprot id: A0A3B4BR50
names: Similarity
messages: Belongs to the oligoribonuclease family.

42514:mpp6b
gene id: 42514:mpp6b
uniprot id: A0A3B4BMF1
uniprot id: A0A3B4DFW0
names: Similarity
messages: Belongs to the MAGUK family.

42514:vegfd
gene id: 42514:vegfd
uniprot id: A0A3B4CB32
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:LOC108431921
gene id: 42514:LOC108431921
uniprot id: A0A3B4C3T8
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

42514:mrps9
gene id: 42514:mrps9
uniprot id: A0A3B4CSE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

42514:slc11a2
gene id: 42514:slc11a2
uniprot id: A0A3B4BPE4
names: Similarity
messages: Belongs to the NRAMP family.

42514:mcm9
gene id: 42514:mcm9
uniprot id: A0A3B4DVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

42514:LOC108422651
gene id: 42514:LOC108422651
uniprot id: A0A3B4CA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

42514:c1galt1b
gene id: 42514:c1galt1b
uniprot id: A0A3B4C892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

42514:LOC108423942
gene id: 42514:LOC108423942
uniprot id: A0A3B4C8G8
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:dhrs9
gene id: 42514:dhrs9
uniprot id: A0A3B4C4H8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108424740
gene id: 42514:LOC108424740
uniprot id: A0A3B4BKC7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:mrpl16
gene id: 42514:mrpl16
uniprot id: A0A3B4DLW6
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

42514:tspan4b
gene id: 42514:tspan4b
uniprot id: A0A3B4E4E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:mst1
gene id: 42514:mst1
uniprot id: A0A3B4C326
names: Caution
names: Similarity
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:grcc10
gene id: 42514:grcc10
uniprot id: A0A3B4C3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

42514:dnmt3bb.1
gene id: 42514:dnmt3bb.1
uniprot id: A0A3B4CFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

42514:mgrn1b
gene id: 42514:mgrn1b
uniprot id: A0A3B4DR62
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin ligase.

42514:zdhhc9
gene id: 42514:zdhhc9
uniprot id: A0A3B4E8D2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:glcea
gene id: 42514:glcea
uniprot id: A0A3B4DIV6
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

42514:si:ch73-62b13.1
gene id: 42514:si:ch73-62b13.1
uniprot id: A0A3B4CPY1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:cmbl
gene id: 42514:cmbl
uniprot id: A0A3B4CJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

42514:tacr3l
gene id: 42514:tacr3l
uniprot id: A0A3B4DS53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:zgc:163057
gene id: 42514:zgc:163057
uniprot id: A0A3B4DRC0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108442218
gene id: 42514:LOC108442218
uniprot id: A0A3B4EHD5
names: Subcellular Location Annotation
messages: Secreted

42514:LOC108423781
gene id: 42514:LOC108423781
uniprot id: A0A3B4E7X4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:adora1b
gene id: 42514:adora1b
uniprot id: A0A3B4BWB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

42514:psmd6
gene id: 42514:psmd6
uniprot id: A0A3B4DVS4
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

42514:LOC108433019
gene id: 42514:LOC108433019
uniprot id: A0A3B4DX93
names: Similarity
messages: Belongs to the cytochrome b5 family.

42514:lect2l
gene id: 42514:lect2l
uniprot id: A0A3B4ECH9
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

42514:LOC108424723
gene id: 42514:LOC108424723
uniprot id: A0A3B4DH85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

42514:zgc:194665
gene id: 42514:zgc:194665
uniprot id: A0A3B4CR28
names: Similarity
messages: Belongs to the TMEM178 family.

42514:ccm2l
gene id: 42514:ccm2l
uniprot id: A0A3B4E3G6
names: Similarity
messages: Belongs to the CCM2 family.

42514:sh3glb1b
gene id: 42514:sh3glb1b
uniprot id: A0A3B4DXX9
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Mitochondrion outer membrane

42514:srp68
gene id: 42514:srp68
uniprot id: A0A3B4DEX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

42514:tecra
gene id: 42514:tecra
uniprot id: A0A3B4CFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

42514:cfap45
gene id: 42514:cfap45
uniprot id: A0A3B4DCY5
uniprot id: A0A3B4EMP7
names: Similarity
messages: Belongs to the CFAP45 family.

42514:actr3
gene id: 42514:actr3
uniprot id: A0A3B4EHT9
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

42514:ins
gene id: 42514:ins
uniprot id: A0A3B4DUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

42514:LOC108440621
gene id: 42514:LOC108440621
uniprot id: A0A3B4CUH5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:ramp2
gene id: 42514:ramp2
uniprot id: A0A3B4E2X4
names: Similarity
messages: Belongs to the RAMP family.

42514:tmem97
gene id: 42514:tmem97
uniprot id: A0A3B4BYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

42514:fam83d
gene id: 42514:fam83d
uniprot id: A0A3B4BU43
names: Similarity
messages: Belongs to the FAM83 family.

42514:LOC108431872
gene id: 42514:LOC108431872
uniprot id: A0A3B4CDQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

42514:glis3
gene id: 42514:glis3
uniprot id: A0A3B4CRR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

42514:glrx
gene id: 42514:glrx
uniprot id: A0A3B4D582
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

42514:vti1b
gene id: 42514:vti1b
uniprot id: A0A3B4C6R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

42514:cwc25
gene id: 42514:cwc25
uniprot id: A0A3B4DB14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus

42514:slc7a3b
gene id: 42514:slc7a3b
uniprot id: A0A3B4EAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:ccr12a
gene id: 42514:ccr12a
uniprot id: A0A3B4C632
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:b4galt5
gene id: 42514:b4galt5
uniprot id: A0A3B4D0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

42514:saraf
gene id: 42514:saraf
uniprot id: A0A3B4CDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:tfap2a
gene id: 42514:tfap2a
uniprot id: A0A3B4D6G5
uniprot id: A0A3B4EIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

42514:cluap1
gene id: 42514:cluap1
uniprot id: A0A3B4C896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

42514:galnt7
gene id: 42514:galnt7
uniprot id: A0A3B4E6Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:gpc1a
gene id: 42514:gpc1a
uniprot id: A0A3B4CYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

42514:nhsl1a
gene id: 42514:nhsl1a
uniprot id: A0A3B4CLI1
uniprot id: A0A3B4E5G1
names: Similarity
messages: Belongs to the NHS family.

42514:LOC108438908
gene id: 42514:LOC108438908
uniprot id: A0A3B4CZB5
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:psph
gene id: 42514:psph
uniprot id: A0A3B4EQ84
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

42514:mos
gene id: 42514:mos
uniprot id: A0A3B4BTB8
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:nkx3-1
gene id: 42514:nkx3-1
uniprot id: A0A3B4CSK0
names: Subcellular Location Annotation
messages: Nucleus

42514:ctps1b
gene id: 42514:ctps1b
uniprot id: A0A3B4CCT1
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

42514:immp2l
gene id: 42514:immp2l
uniprot id: A0A3B4CIU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Membrane
messages: Mitochondrion inner membrane

42514:kifc3
gene id: 42514:kifc3
uniprot id: A0A3B4CPL5
uniprot id: A0A3B4E8L3
uniprot id: A0A3B4EA26
uniprot id: A0A3B4EA87
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:ndufs4
gene id: 42514:ndufs4
uniprot id: A0A3B4D7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mitochondrion inner membrane

42514:foxf2b
gene id: 42514:foxf2b
uniprot id: A0A3B4D3I1
names: Subcellular Location Annotation
messages: Nucleus

42514:niban2b
gene id: 42514:niban2b
uniprot id: A0A3B4CSQ2
names: Similarity
messages: Belongs to the Niban family.

42514:slc26a6
gene id: 42514:slc26a6
uniprot id: A0A3B4CMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

42514:hspb8
gene id: 42514:hspb8
uniprot id: A0A3B4BZI6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:penkb
gene id: 42514:penkb
uniprot id: A0A3B4CW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

42514:miga2
gene id: 42514:miga2
uniprot id: A0A3B4CGX7
names: Similarity
messages: Belongs to the mitoguardin family.

42514:LOC108411656
gene id: 42514:LOC108411656
uniprot id: A0A3B4CT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:med25
gene id: 42514:med25
uniprot id: A0A3B4C266
uniprot id: A0A3B4DTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 25 family.
messages: Nucleus

42514:wnt5b
gene id: 42514:wnt5b
uniprot id: A0A3B4D4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:unm hu7910
gene id: 42514:unm_hu7910
uniprot id: A0A3B4CRZ0
uniprot id: A0A3B4E806
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

42514:mgmt
gene id: 42514:mgmt
uniprot id: A0A3B4D7C8
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

42514:ism2b
gene id: 42514:ism2b
uniprot id: A0A3B4BNV8
names: Similarity
messages: Belongs to the isthmin family.

42514:LOC108443050
gene id: 42514:LOC108443050
uniprot id: A0A3B4D157
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

42514:jmy
gene id: 42514:jmy
uniprot id: A0A3B4BQV7
names: Subcellular Location Annotation
messages: Membrane

42514:phf10
gene id: 42514:phf10
uniprot id: A0A3B4C4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

42514:LOC108439875
gene id: 42514:LOC108439875
uniprot id: A0A3B4DDV7
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

42514:LOC108441221
gene id: 42514:LOC108441221
uniprot id: A0A3B4E6M1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:pclob
gene id: 42514:pclob
uniprot id: A0A3B4CZG8
uniprot id: A0A3B4D001
names: Subcellular Location Annotation
messages: Presynaptic active zone

42514:mysm1
gene id: 42514:mysm1
uniprot id: A0A3B4DGG8
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

42514:dhps
gene id: 42514:dhps
uniprot id: A0A3B4BSN0
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

42514:LOC108436866
gene id: 42514:LOC108436866
uniprot id: A0A3B4CQK7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:ctnnb1
gene id: 42514:ctnnb1
uniprot id: A0A3B4CUD5
uniprot id: A0A3B4EAA1
uniprot id: A0A3B4EAM0
names: Similarity
messages: Belongs to the beta-catenin family.

42514:st8sia4
gene id: 42514:st8sia4
uniprot id: A0A3B4EAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:LOC108428722
gene id: 42514:LOC108428722
uniprot id: A0A3B4DIS2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

42514:cdkn1cb
gene id: 42514:cdkn1cb
uniprot id: A0A3B4BSJ4
names: Similarity
messages: Belongs to the CDI family.

42514:LOC108430767
gene id: 42514:LOC108430767
uniprot id: A0A3B4CIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

42514:pah
gene id: 42514:pah
uniprot id: A0A3B4CED1
uniprot id: A0A3B4CED6
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

42514:ccn1l2
gene id: 42514:ccn1l2
uniprot id: A0A3B4CYW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:acte1
gene id: 42514:acte1
uniprot id: A0A3B4C5P3
names: Similarity
messages: Belongs to the actin family.

42514:hoxc11a
gene id: 42514:hoxc11a
uniprot id: A0A3B4CUV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:ehd2a
gene id: 42514:ehd2a
uniprot id: A0A3B4E4Z8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

42514:st3gal3a
gene id: 42514:st3gal3a
uniprot id: A0A3B4DAR7
uniprot id: A0A3B4ELQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:pnpla4
gene id: 42514:pnpla4
uniprot id: A0A3B4CYD7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:cops8
gene id: 42514:cops8
uniprot id: A0A3B4D8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

42514:ppt2b
gene id: 42514:ppt2b
uniprot id: A0A3B4C935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the palmitoyl-protein thioesterase family.
messages: Lysosome

42514:supt3h
gene id: 42514:supt3h
uniprot id: A0A3B4CSA5
names: Subcellular Location Annotation
messages: Nucleus

42514:kcnj14
gene id: 42514:kcnj14
uniprot id: A0A3B4E7D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:washc3
gene id: 42514:washc3
uniprot id: A0A3B4CLI4
names: Similarity
messages: Belongs to the CCDC53 family.

42514:nat10
gene id: 42514:nat10
uniprot id: A0A3B4CRJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

42514:LOC108414896
gene id: 42514:LOC108414896
uniprot id: A0A3B4C6B5
names: Similarity
messages: Belongs to the ATG8 family.

42514:gpm6aa
gene id: 42514:gpm6aa
uniprot id: A0A3B4E6B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

42514:scfd1
gene id: 42514:scfd1
uniprot id: A0A3B4CR96
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

42514:iqsec1b
gene id: 42514:iqsec1b
uniprot id: A0A3B4BPC1
names: Similarity
messages: Belongs to the BRAG family.

42514:stip1
gene id: 42514:stip1
uniprot id: A0A3B4EDI4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:psmb12
gene id: 42514:psmb12
uniprot id: A0A3B4DQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

42514:dmrt2b
gene id: 42514:dmrt2b
uniprot id: A0A3B4DQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

42514:tomm40l
gene id: 42514:tomm40l
uniprot id: A0A3B4DL66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:emc1
gene id: 42514:emc1
uniprot id: A0A3B4EF09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:ctdp1
gene id: 42514:ctdp1
uniprot id: A0A3B4DS03
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

42514:azin1b
gene id: 42514:azin1b
uniprot id: A0A3B4C0C6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

42514:LOC108440251
gene id: 42514:LOC108440251
uniprot id: A0A3B4DX02
names: Similarity
messages: Belongs to the globin family.

42514:desi1b
gene id: 42514:desi1b
uniprot id: A0A3B4CB07
names: Similarity
messages: Belongs to the DeSI family.

42514:eif3d
gene id: 42514:eif3d
uniprot id: A0A3B4DH79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

42514:capn12
gene id: 42514:capn12
uniprot id: A0A3B4E7C8
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:nr1i2
gene id: 42514:nr1i2
uniprot id: A0A3B4CTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:LOC108411210
gene id: 42514:LOC108411210
uniprot id: A0A3B4CAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

42514:celf2
gene id: 42514:celf2
uniprot id: A0A3B4BW93
uniprot id: A0A3B4DN77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108433564
gene id: 42514:LOC108433564
uniprot id: A0A3B4E1E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:szl
gene id: 42514:szl
uniprot id: A0A3B4CMM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:fuca1.2
gene id: 42514:fuca1.2
uniprot id: A0A3B4BZZ4
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

42514:nucb2a
gene id: 42514:nucb2a
uniprot id: A0A3B4DY96
names: Similarity
messages: Belongs to the nucleobindin family.

42514:usp48
gene id: 42514:usp48
uniprot id: A0A3B4E200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

42514:ace
gene id: 42514:ace
uniprot id: A0A3B4DX39
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

42514:zdhhc11
gene id: 42514:zdhhc11
uniprot id: A0A3B4DMA4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:LOC108431927
gene id: 42514:LOC108431927
uniprot id: A0A3B4C5E3
names: Function
names: Subcellular Location Annotation
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: filopodium
messages: microvillus
messages: ruffle

42514:clcn5a
gene id: 42514:clcn5a
uniprot id: A0A3B4CBI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:si:ch211-14k19.8
gene id: 42514:si:ch211-14k19.8
uniprot id: A0A3B4C3I3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:slc37a4a
gene id: 42514:slc37a4a
uniprot id: A0A3B4DN89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

42514:LOC108443875
gene id: 42514:LOC108443875
uniprot id: A0A3B4BPQ4
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108428979
gene id: 42514:LOC108428979
uniprot id: A0A3B4CWI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:ppm1f
gene id: 42514:ppm1f
uniprot id: A0A3B4E9W4
names: Similarity
messages: Belongs to the PP2C family.

42514:unc5a
gene id: 42514:unc5a
uniprot id: A0A3B4DUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

42514:folr
gene id: 42514:folr
uniprot id: A0A3B4DJ87
names: Similarity
messages: Belongs to the folate receptor family.

42514:ppat
gene id: 42514:ppat
uniprot id: A0A3B4DJJ0
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

42514:rpe65a
gene id: 42514:rpe65a
uniprot id: A0A3B4CP87
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

42514:tfip11
gene id: 42514:tfip11
uniprot id: A0A3B4CG43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFP11/STIP family.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events.
messages: Nucleus

42514:flot1b
gene id: 42514:flot1b
uniprot id: A0A3B4EAL1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

42514:kdm2aa
gene id: 42514:kdm2aa
uniprot id: A0A3B4CD92
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

42514:prdm6
gene id: 42514:prdm6
uniprot id: A0A3B4DNH2
names: Subcellular Location Annotation
messages: Nucleus

42514:pex13
gene id: 42514:pex13
uniprot id: A0A3B4DLT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

42514:dynlrb2
gene id: 42514:dynlrb2
uniprot id: A0A3B4ERA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

42514:rrp8
gene id: 42514:rrp8
uniprot id: A0A3B4EGV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Probable methyltransferase required to silence rDNA.
messages: nucleolus

42514:tmem54a
gene id: 42514:tmem54a
uniprot id: A0A3B4D3J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

42514:LOC108443884
gene id: 42514:LOC108443884
uniprot id: A0A3B4BPH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:ptdss1b
gene id: 42514:ptdss1b
uniprot id: A0A3B4D4T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:prkar1aa
gene id: 42514:prkar1aa
uniprot id: A0A3B4CD71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

42514:arvcfb
gene id: 42514:arvcfb
uniprot id: A0A3B4D298
uniprot id: A0A3B4EEY1
uniprot id: A0A3B4EG59
uniprot id: A0A3B4EGB1
names: Similarity
messages: Belongs to the beta-catenin family.

42514:gabrg1
gene id: 42514:gabrg1
uniprot id: A0A3B4CBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:lacc1
gene id: 42514:lacc1
uniprot id: A0A3B4E587
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

42514:scara5
gene id: 42514:scara5
uniprot id: A0A3B4DUK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways.
messages: Homotrimer.
messages: Membrane

42514:tspan31
gene id: 42514:tspan31
uniprot id: A0A3B4EA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:frrs1b
gene id: 42514:frrs1b
uniprot id: A0A3B4CW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

42514:LOC108442344
gene id: 42514:LOC108442344
uniprot id: A0A3B4E7N3
names: Similarity
messages: Belongs to the NAD kinase family.

42514:LOC108441115
gene id: 42514:LOC108441115
uniprot id: A0A3B4EG16
names: Subcellular Location Annotation
messages: Nucleus

42514:lars1b
gene id: 42514:lars1b
uniprot id: A0A3B4DB18
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:smarcd3a
gene id: 42514:smarcd3a
uniprot id: A0A3B4DAT1
uniprot id: A0A3B4EPN2
uniprot id: A0A3B4EPP3
names: Similarity
messages: Belongs to the SMARCD family.

42514:coq8aa
gene id: 42514:coq8aa
uniprot id: A0A3B4EQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

42514:ago3b
gene id: 42514:ago3b
uniprot id: A0A3B4BS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

42514:ddc
gene id: 42514:ddc
uniprot id: A0A3B4DV82
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

42514:kif25
gene id: 42514:kif25
uniprot id: A0A3B4CWD5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:galr1b
gene id: 42514:galr1b
uniprot id: A0A3B4CCI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:LOC108436231
gene id: 42514:LOC108436231
uniprot id: A0A3B4CLD8
names: Similarity
messages: Belongs to the DDIT4 family.

42514:plxnb2a
gene id: 42514:plxnb2a
uniprot id: A0A3B4D1E2
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:sfmbt2
gene id: 42514:sfmbt2
uniprot id: A0A3B4DIB3
names: Subcellular Location Annotation
messages: Nucleus

42514:srfbp1
gene id: 42514:srfbp1
uniprot id: A0A3B4EQX0
names: Function
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

42514:srsf1b
gene id: 42514:srsf1b
uniprot id: A0A3B4CAR6
names: Similarity
messages: Belongs to the splicing factor SR family.

42514:lin7c
gene id: 42514:lin7c
uniprot id: A0A3B4CR07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

42514:osbpl3a
gene id: 42514:osbpl3a
uniprot id: A0A3B4BR20
names: Similarity
messages: Belongs to the OSBP family.

42514:gosr1
gene id: 42514:gosr1
uniprot id: A0A3B4BTS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

42514:dis3l2
gene id: 42514:dis3l2
uniprot id: A0A3B4DFG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

42514:pld1a
gene id: 42514:pld1a
uniprot id: A0A3B4CQ92
names: Similarity
messages: Belongs to the phospholipase D family.

42514:clcnk
gene id: 42514:clcnk
uniprot id: A0A3B4E9U7
names: Subcellular Location Annotation
messages: Membrane

42514:riox2
gene id: 42514:riox2
uniprot id: A0A3B4E7D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. MINA53 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

42514:hoxa9b
gene id: 42514:hoxa9b
uniprot id: A0A3B4BSG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:LOC108440473
gene id: 42514:LOC108440473
uniprot id: A0A3B4DC76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:igfbp1a
gene id: 42514:igfbp1a
uniprot id: A0A3B4DDQ8
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:dlk2
gene id: 42514:dlk2
uniprot id: A0A3B4C4M3
uniprot id: A0A3B4C4P2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ndufs1
gene id: 42514:ndufs1
uniprot id: A0A3B4BS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

42514:si:dkey-197c15.6
gene id: 42514:si:dkey-197c15.6
uniprot id: A0A3B4D8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

42514:prkcg
gene id: 42514:prkcg
uniprot id: A0A3B4E2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

42514:hrh3
gene id: 42514:hrh3
uniprot id: A0A3B4DZE6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:pde6a
gene id: 42514:pde6a
uniprot id: A0A3B4EFD6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:LOC108426790
gene id: 42514:LOC108426790
uniprot id: A0A3B4E151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

42514:tm2d2
gene id: 42514:tm2d2
uniprot id: A0A3B4BSV3
names: Subcellular Location Annotation
messages: Membrane

42514:skor2
gene id: 42514:skor2
uniprot id: A0A3B4DA26
names: Similarity
messages: Belongs to the SKI family.

42514:timm22
gene id: 42514:timm22
uniprot id: A0A3B4ENM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

42514:tmem201
gene id: 42514:tmem201
uniprot id: A0A3B4CYB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

42514:ldb2b
gene id: 42514:ldb2b
uniprot id: A0A3B4BSC2
names: Similarity
messages: Belongs to the LDB family.

42514:ppm1aa
gene id: 42514:ppm1aa
uniprot id: A0A3B4DI63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

42514:kri1
gene id: 42514:kri1
uniprot id: A0A3B4D427
names: Similarity
messages: Belongs to the KRI1 family.

42514:e2f4
gene id: 42514:e2f4
uniprot id: A0A3B4DUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:golga5
gene id: 42514:golga5
uniprot id: A0A3B4C9V7
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

42514:aqp8a.2
gene id: 42514:aqp8a.2
uniprot id: A0A3B4DRK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:ndufa5
gene id: 42514:ndufa5
uniprot id: A0A3B4DZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

42514:actr8
gene id: 42514:actr8
uniprot id: A0A3B4BZE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

42514:LOC108427799
gene id: 42514:LOC108427799
uniprot id: A0A3B4CYC5
uniprot id: A0A3B4D0L4
uniprot id: A0A3B4ED89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

42514:LOC108429797
gene id: 42514:LOC108429797
uniprot id: A0A3B4DQE6
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

42514:sord
gene id: 42514:sord
uniprot id: A0A3B4BPL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Mitochondrion membrane
messages: flagellum

42514:atp2a1
gene id: 42514:atp2a1
uniprot id: A0A3B4D006
uniprot id: A0A3B4EAI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

42514:si:ch1073-280e3.1
gene id: 42514:si:ch1073-280e3.1
uniprot id: A0A3B4C3E6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:dop1b
gene id: 42514:dop1b
uniprot id: A0A3B4BNR0
names: Similarity
messages: Belongs to the dopey family.

42514:jag2b
gene id: 42514:jag2b
uniprot id: A0A3B4DEF1
uniprot id: A0A3B4EM83
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

42514:b4gat1
gene id: 42514:b4gat1
uniprot id: A0A3B4C1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:slc5a6b
gene id: 42514:slc5a6b
uniprot id: A0A3B4BLA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:onecut1
gene id: 42514:onecut1
uniprot id: A0A3B4D1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

42514:nup93
gene id: 42514:nup93
uniprot id: A0A3B4CJD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

42514:mpv17l2
gene id: 42514:mpv17l2
uniprot id: A0A3B4CHH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

42514:foxk2
gene id: 42514:foxk2
uniprot id: A0A3B4EK33
names: Subcellular Location Annotation
messages: Nucleus

42514:nrn1lb
gene id: 42514:nrn1lb
uniprot id: A0A3B4CDQ5
names: Similarity
messages: Belongs to the neuritin family.

42514:LOC108434037
gene id: 42514:LOC108434037
uniprot id: A0A3B4CIY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:tmem41aa
gene id: 42514:tmem41aa
uniprot id: A0A3B4CB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

42514:chac2
gene id: 42514:chac2
uniprot id: A0A3B4EJC0
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

42514:prkab1a
gene id: 42514:prkab1a
uniprot id: A0A3B4D285
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

42514:LOC108413345
gene id: 42514:LOC108413345
uniprot id: A0A3B4EI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

42514:ntmt1
gene id: 42514:ntmt1
uniprot id: A0A3B4EEE1
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

42514:ciapin1
gene id: 42514:ciapin1
uniprot id: A0A3B4DTP7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

42514:gcnt4a
gene id: 42514:gcnt4a
uniprot id: A0A3B4DE67
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

42514:uchl5
gene id: 42514:uchl5
uniprot id: A0A3B4DET6
names: Similarity
messages: Belongs to the peptidase C12 family.

42514:bag6
gene id: 42514:bag6
uniprot id: A0A3B4DLP3
names: Subcellular Location Annotation
messages: Nucleus
messages: extracellular exosome

42514:syn2b
gene id: 42514:syn2b
uniprot id: A0A3B4BSP8
names: Similarity
messages: Belongs to the synapsin family.

42514:rps6ka2
gene id: 42514:rps6ka2
uniprot id: A0A3B4D8Y7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

42514:esr2a
gene id: 42514:esr2a
uniprot id: A0A3B4CLM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

42514:atp6v1h
gene id: 42514:atp6v1h
uniprot id: A0A3B4CRE9
uniprot id: A0A3B4CRF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

42514:fgf11a
gene id: 42514:fgf11a
uniprot id: A0A3B4DSL6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:bcl2l1
gene id: 42514:bcl2l1
uniprot id: A0A3B4DTL9
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:slc35e4
gene id: 42514:slc35e4
uniprot id: A0A3B4BWI2
names: Subcellular Location Annotation
messages: Membrane

42514:acaa2
gene id: 42514:acaa2
uniprot id: A0A3B4BPW8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

42514:LOC108436081
gene id: 42514:LOC108436081
uniprot id: A0A3B4CTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

42514:LOC108417198
gene id: 42514:LOC108417198
uniprot id: A0A3B4D896
uniprot id: A0A3B4EHF4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

42514:coch
gene id: 42514:coch
uniprot id: A0A3B4E4E3
names: Function
messages: Plays a role in the control of cell shape and motility in the trabecular meshwork.

42514:si:ch211-210c8.6
gene id: 42514:si:ch211-210c8.6
uniprot id: A0A3B4EE61
names: Subcellular Location Annotation
messages: Membrane

42514:acta1b
gene id: 42514:acta1b
uniprot id: A0A3B4CCF9
names: Similarity
messages: Belongs to the actin family.

42514:LOC108431586
gene id: 42514:LOC108431586
uniprot id: A0A3B4DDD8
names: Similarity
messages: Belongs to the DNase I family.

42514:zgc:100920
gene id: 42514:zgc:100920
uniprot id: A0A3B4C5N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

42514:man1a2
gene id: 42514:man1a2
uniprot id: A0A3B4D513
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:cln5
gene id: 42514:cln5
uniprot id: A0A3B4CK61
names: Similarity
messages: Belongs to the CLN5 family.

42514:pcsk2
gene id: 42514:pcsk2
uniprot id: A0A3B4EJ46
names: Similarity
messages: Belongs to the peptidase S8 family.

42514:dnal4b
gene id: 42514:dnal4b
uniprot id: A0A3B4DC97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

42514:rab11fip3
gene id: 42514:rab11fip3
uniprot id: A0A3B4DUF4
uniprot id: A0A3B4DVL8
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

42514:LOC108432260
gene id: 42514:LOC108432260
uniprot id: A0A3B4EEE5
names: Similarity
messages: Belongs to the RBR family.

42514:kcnn3
gene id: 42514:kcnn3
uniprot id: A0A3B4DBH8
names: Subcellular Location Annotation
messages: Membrane

42514:pik3ip1
gene id: 42514:pik3ip1
uniprot id: A0A3B4DTC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:zdhhc23a
gene id: 42514:zdhhc23a
uniprot id: A0A3B4BZU1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:med12
gene id: 42514:med12
uniprot id: A0A3B4E4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

42514:rps6kal
gene id: 42514:rps6kal
uniprot id: A0A3B4C256
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

42514:LOC108413414
gene id: 42514:LOC108413414
uniprot id: A0A3B4CZM3
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:rnf34b
gene id: 42514:rnf34b
uniprot id: A0A3B4DZJ6
uniprot id: A0A3B4E2A4
names: Subcellular Location Annotation
messages: Cell membrane

42514:proca1
gene id: 42514:proca1
uniprot id: A0A3B4CCA9
names: Subcellular Location Annotation
messages: Secreted

42514:LOC108413312
gene id: 42514:LOC108413312
uniprot id: A0A3B4DAS1
uniprot id: A0A3B4DBT2
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:ankrd34ba
gene id: 42514:ankrd34ba
uniprot id: A0A3B4C2L0
names: Similarity
messages: Belongs to the ANKRD34 family.

42514:LOC108424690
gene id: 42514:LOC108424690
uniprot id: A0A3B4ER22
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108431253
gene id: 42514:LOC108431253
uniprot id: A0A3B4DZ72
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108425223
gene id: 42514:LOC108425223
uniprot id: A0A3B4BZP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

42514:LOC108423911
gene id: 42514:LOC108423911
uniprot id: A0A3B4E0A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

42514:smad1
gene id: 42514:smad1
uniprot id: A0A3B4CLW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:atp6v0ca
gene id: 42514:atp6v0ca
uniprot id: A0A3B4C427
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

42514:LOC108434245
gene id: 42514:LOC108434245
uniprot id: A0A3B4DP03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

42514:entpd3
gene id: 42514:entpd3
uniprot id: A0A3B4CTY3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:LOC108438913
gene id: 42514:LOC108438913
uniprot id: A0A3B4D2U3
names: Subcellular Location Annotation
messages: Membrane

42514:dgcr2
gene id: 42514:dgcr2
uniprot id: A0A3B4CGD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:trpc5a
gene id: 42514:trpc5a
uniprot id: A0A3B4EIJ4
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108431472
gene id: 42514:LOC108431472
uniprot id: A0A3B4DN43
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

42514:gpc5b
gene id: 42514:gpc5b
uniprot id: A0A3B4EC85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

42514:prkrip1
gene id: 42514:prkrip1
uniprot id: A0A3B4CEH6
names: Similarity
messages: Belongs to the PRKRIP1 family.

42514:tmcc2
gene id: 42514:tmcc2
uniprot id: A0A3B4BZR5
names: Similarity
messages: Belongs to the TEX28 family.

42514:cdk6
gene id: 42514:cdk6
uniprot id: A0A3B4BQU9
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:nr5a2
gene id: 42514:nr5a2
uniprot id: A0A3B4CCJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

42514:nr2f5
gene id: 42514:nr2f5
uniprot id: A0A3B4DF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:psmd2
gene id: 42514:psmd2
uniprot id: A0A3B4BVP6
uniprot id: A0A3B4DP07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

42514:mpp3a
gene id: 42514:mpp3a
uniprot id: A0A3B4BTN7
uniprot id: A0A3B4DLB9
names: Similarity
messages: Belongs to the MAGUK family.

42514:epn1
gene id: 42514:epn1
uniprot id: A0A3B4CKC2
uniprot id: A0A3B4CKC9
names: Similarity
messages: Belongs to the epsin family.

42514:LOC108410903
gene id: 42514:LOC108410903
uniprot id: A0A3B4EPS7
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

42514:hspa4l
gene id: 42514:hspa4l
uniprot id: A0A3B4CLG8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:cdc42ep4a
gene id: 42514:cdc42ep4a
uniprot id: A0A3B4EFW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

42514:sfr1
gene id: 42514:sfr1
uniprot id: A0A3B4CC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

42514:csrnp1b
gene id: 42514:csrnp1b
uniprot id: A0A3B4E802
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

42514:wdyhv1
gene id: 42514:wdyhv1
uniprot id: A0A3B4BUU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NTAQ1 family.
messages: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.
messages: Monomer.

42514:ergic2
gene id: 42514:ergic2
uniprot id: A0A3B4CQK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

42514:nipblb
gene id: 42514:nipblb
uniprot id: A0A3B4CC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

42514:mpped2a
gene id: 42514:mpped2a
uniprot id: A0A3B4EG74
names: Similarity
messages: Belongs to the UPF0046 family.

42514:ufm1
gene id: 42514:ufm1
uniprot id: A0A3B4CKQ6
uniprot id: A0A3B4E4L7
names: Function
names: Similarity
messages: Belongs to the UFM1 family.
messages: Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

42514:nemp2
gene id: 42514:nemp2
uniprot id: A0A3B4E874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

42514:dusp27
gene id: 42514:dusp27
uniprot id: A0A3B4C335
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

42514:csgalnact2
gene id: 42514:csgalnact2
uniprot id: A0A3B4CGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

42514:wnt8a
gene id: 42514:wnt8a
uniprot id: A0A3B4CU04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:slc39a4
gene id: 42514:slc39a4
uniprot id: A0A3B4E4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

42514:dap3
gene id: 42514:dap3
uniprot id: A0A3B4CN05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

42514:LOC108432721
gene id: 42514:LOC108432721
uniprot id: A0A3B4DE08
uniprot id: A0A3B4DE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

42514:stk17a
gene id: 42514:stk17a
uniprot id: A0A3B4BP06
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108425541
gene id: 42514:LOC108425541
uniprot id: A0A3B4CUC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

42514:LOC108411854
gene id: 42514:LOC108411854
uniprot id: A0A3B4CB59
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:armc1l
gene id: 42514:armc1l
uniprot id: A0A3B4CNK1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

42514:hacd3
gene id: 42514:hacd3
uniprot id: A0A3B4CE11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:papolg
gene id: 42514:papolg
uniprot id: A0A3B4E116
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

42514:thop1
gene id: 42514:thop1
uniprot id: A0A3B4D2T3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

42514:hapln1b
gene id: 42514:hapln1b
uniprot id: A0A3B4BUV9
uniprot id: A0A3B4DIM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tafa5l
gene id: 42514:tafa5l
uniprot id: A0A3B4CH40
names: Similarity
messages: Belongs to the TAFA family.

42514:gabrd
gene id: 42514:gabrd
uniprot id: A0A3B4DSN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:LOC108432852
gene id: 42514:LOC108432852
uniprot id: A0A3B4D067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

42514:impdh2
gene id: 42514:impdh2
uniprot id: A0A3B4CT00
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

42514:LOC108424755
gene id: 42514:LOC108424755
uniprot id: A0A3B4EN49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:ipo8
gene id: 42514:ipo8
uniprot id: A0A3B4DPL4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108411014
gene id: 42514:LOC108411014
uniprot id: A0A3B4D305
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

42514:csnk2a4
gene id: 42514:csnk2a4
uniprot id: A0A3B4BQY0
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:tgif1
gene id: 42514:tgif1
uniprot id: A0A3B4EP25
names: Subcellular Location Annotation
messages: Nucleus

42514:myo7ab
gene id: 42514:myo7ab
uniprot id: A0A3B4CFK9
uniprot id: A0A3B4CH44
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:bcl9
gene id: 42514:bcl9
uniprot id: A0A3B4EMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

42514:dtx4b
gene id: 42514:dtx4b
uniprot id: A0A3B4DUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

42514:cnot7
gene id: 42514:cnot7
uniprot id: A0A3B4EAG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

42514:adssl
gene id: 42514:adssl
uniprot id: A0A3B4DSA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

42514:lin7b
gene id: 42514:lin7b
uniprot id: A0A3B4E5W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-7 family.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.

42514:LOC108427596
gene id: 42514:LOC108427596
uniprot id: A0A3B4BUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

42514:LOC108441624
gene id: 42514:LOC108441624
uniprot id: A0A3B4EL56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

42514:npc1l1
gene id: 42514:npc1l1
uniprot id: A0A3B4CNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

42514:LOC108440331
gene id: 42514:LOC108440331
uniprot id: A0A3B4DP83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

42514:utp23
gene id: 42514:utp23
uniprot id: A0A3B4EHZ8
names: Subcellular Location Annotation
messages: nucleolus

42514:LOC108441319
gene id: 42514:LOC108441319
uniprot id: A0A3B4E133
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:sts
gene id: 42514:sts
uniprot id: A0A3B4CZY6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:eps8l3b
gene id: 42514:eps8l3b
uniprot id: A0A3B4EE83
names: Similarity
messages: Belongs to the EPS8 family.

42514:ttc21b
gene id: 42514:ttc21b
uniprot id: A0A3B4D1H8
names: Similarity
messages: Belongs to the TTC21 family.

42514:kif3b
gene id: 42514:kif3b
uniprot id: A0A3B4BWF9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:shoc2
gene id: 42514:shoc2
uniprot id: A0A3B4E622
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

42514:fscn2b
gene id: 42514:fscn2b
uniprot id: A0A3B4D9C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

42514:ano10a
gene id: 42514:ano10a
uniprot id: A0A3B4ECY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

42514:adck2
gene id: 42514:adck2
uniprot id: A0A3B4D382
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

42514:si:dkey-85n7.8
gene id: 42514:si:dkey-85n7.8
uniprot id: A0A3B4DK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:ppm1na
gene id: 42514:ppm1na
uniprot id: A0A3B4DN31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

42514:ywhae1
gene id: 42514:ywhae1
uniprot id: A0A3B4BXG4
uniprot id: A0A3B4DK98
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:mcu
gene id: 42514:mcu
uniprot id: A0A3B4D9S8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

42514:LOC108443080
gene id: 42514:LOC108443080
uniprot id: A0A3B4C7Z3
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:zmp:0000001114
gene id: 42514:zmp:0000001114
uniprot id: A0A3B4DAS9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:zgc:103681
gene id: 42514:zgc:103681
uniprot id: A0A3B4DLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

42514:stc1
gene id: 42514:stc1
uniprot id: A0A3B4CV08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

42514:slc30a5
gene id: 42514:slc30a5
uniprot id: A0A3B4DBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

42514:LOC108431496
gene id: 42514:LOC108431496
uniprot id: A0A3B4BQJ2
names: Similarity
messages: Belongs to the cytochrome b5 family.

42514:mtx1b
gene id: 42514:mtx1b
uniprot id: A0A3B4EQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:prr5l
gene id: 42514:prr5l
uniprot id: A0A3B4E1J2
names: Similarity
messages: Belongs to the PROTOR family.

42514:atpaf1
gene id: 42514:atpaf1
uniprot id: A0A3B4CWG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

42514:adam10a
gene id: 42514:adam10a
uniprot id: A0A3B4EBH6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:pdk2a
gene id: 42514:pdk2a
uniprot id: A0A3B4BPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

42514:tmem242
gene id: 42514:tmem242
uniprot id: A0A3B4EI56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

42514:cdh4
gene id: 42514:cdh4
uniprot id: A0A3B4C8G6
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:zcchc8
gene id: 42514:zcchc8
uniprot id: A0A3B4CS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC8 family.
messages: nucleoplasm

42514:tle2c
gene id: 42514:tle2c
uniprot id: A0A3B4EGN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:adcy7
gene id: 42514:adcy7
uniprot id: A0A3B4D2M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:il17d
gene id: 42514:il17d
uniprot id: A0A3B4DPQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

42514:mul1a
gene id: 42514:mul1a
uniprot id: A0A3B4CW21
names: Subcellular Location Annotation
messages: Membrane

42514:rbm48
gene id: 42514:rbm48
uniprot id: A0A3B4BRC7
names: Similarity
messages: Belongs to the RBM48 family.

42514:mapk8b
gene id: 42514:mapk8b
uniprot id: A0A3B4EEH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

42514:sh2b1
gene id: 42514:sh2b1
uniprot id: A0A3B4CMF9
names: Similarity
messages: Belongs to the SH2B adapter family.

42514:msx2a
gene id: 42514:msx2a
uniprot id: A0A3B4DPE5
names: Subcellular Location Annotation
messages: Nucleus

42514:tm9sf4
gene id: 42514:tm9sf4
uniprot id: A0A3B4DJN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

42514:ube2l3b
gene id: 42514:ube2l3b
uniprot id: A0A3B4EBB3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:gja5b
gene id: 42514:gja5b
uniprot id: A0A3B4DFK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:slc26a11
gene id: 42514:slc26a11
uniprot id: A0A3B4CZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

42514:gria4b
gene id: 42514:gria4b
uniprot id: A0A3B4CIL8
uniprot id: A0A3B4CK26
uniprot id: A0A3B4E4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:LOC108442566
gene id: 42514:LOC108442566
uniprot id: A0A3B4BSR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:inpp5kb
gene id: 42514:inpp5kb
uniprot id: A0A3B4D363
uniprot id: A0A3B4D5Q8
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

42514:pkd1a
gene id: 42514:pkd1a
uniprot id: A0A3B4DEZ2
uniprot id: A0A3B4EPF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:eif4ebp1
gene id: 42514:eif4ebp1
uniprot id: A0A3B4E340
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

42514:pard6b
gene id: 42514:pard6b
uniprot id: A0A3B4C9N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

42514:LOC108437854
gene id: 42514:LOC108437854
uniprot id: A0A3B4E894
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

42514:phactr4b
gene id: 42514:phactr4b
uniprot id: A0A3B4CXV5
uniprot id: A0A3B4CY03
uniprot id: A0A3B4EEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

42514:cab39
gene id: 42514:cab39
uniprot id: A0A3B4D628
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

42514:psmc2
gene id: 42514:psmc2
uniprot id: A0A3B4CG18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

42514:ribc2
gene id: 42514:ribc2
uniprot id: A0A3B4DNV5
names: Similarity
messages: Belongs to the RIB43A family.

42514:hdac8
gene id: 42514:hdac8
uniprot id: A0A3B4DQH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. In addition to protein deacetylase activity, also has protein-lysine deacylase activity: acts as a protein decrotonylase by mediating decrotonylation ((2E)-butenoyl) of histones.
messages: Nucleus

42514:six3b
gene id: 42514:six3b
uniprot id: A0A3B4DKQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

42514:ssbp1
gene id: 42514:ssbp1
uniprot id: A0A3B4CUV6
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

42514:zgc:101569
gene id: 42514:zgc:101569
uniprot id: A0A3B4EGD8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

42514:LOC108412093
gene id: 42514:LOC108412093
uniprot id: A0A3B4E5S7
names: Similarity
messages: Belongs to the proline racemase family.

42514:ddx49
gene id: 42514:ddx49
uniprot id: A0A3B4E2X9
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:fmc1
gene id: 42514:fmc1
uniprot id: A0A3B4CE39
names: Similarity
messages: Belongs to the FMC1 family.

42514:rnf170
gene id: 42514:rnf170
uniprot id: A0A3B4C6L0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:foxp1b
gene id: 42514:foxp1b
uniprot id: A0A3B4BNH2
names: Subcellular Location Annotation
messages: Nucleus

42514:cfap36
gene id: 42514:cfap36
uniprot id: A0A3B4C0C5
names: Similarity
messages: Belongs to the CFAP36 family.

42514:LOC108440211
gene id: 42514:LOC108440211
uniprot id: A0A3B4C6A7
names: Similarity
messages: Belongs to the globin family.

42514:rrm1
gene id: 42514:rrm1
uniprot id: A0A3B4DW33
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

42514:fam160a1a
gene id: 42514:fam160a1a
uniprot id: A0A3B4EAQ4
names: Similarity
messages: Belongs to the FHIP family.

42514:fam20cl
gene id: 42514:fam20cl
uniprot id: A0A3B4DBV5
names: Similarity
messages: Belongs to the FAM20 family.

42514:LOC108427444
gene id: 42514:LOC108427444
uniprot id: A0A3B4E2B5
names: Subcellular Location Annotation
messages: tight junction

42514:neu4
gene id: 42514:neu4
uniprot id: A0A3B4DL41
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

42514:arhgef28a
gene id: 42514:arhgef28a
uniprot id: A0A3B4CT13
uniprot id: A0A3B4EB58
uniprot id: A0A3B4ECI4
names: Subcellular Location Annotation
messages: Cytoplasm

42514:pycr3
gene id: 42514:pycr3
uniprot id: A0A3B4BRA9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

42514:ube2e2
gene id: 42514:ube2e2
uniprot id: A0A3B4EGZ9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:vdac2
gene id: 42514:vdac2
uniprot id: A0A3B4DAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

42514:txnl4b
gene id: 42514:txnl4b
uniprot id: A0A3B4DR29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

42514:atrnl1b
gene id: 42514:atrnl1b
uniprot id: A0A3B4DF62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:lamb2
gene id: 42514:lamb2
uniprot id: A0A3B4EHA4
uniprot id: A0A3B4EIU5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

42514:nucb2b
gene id: 42514:nucb2b
uniprot id: A0A3B4E7E8
names: Similarity
messages: Belongs to the nucleobindin family.

42514:xkrx
gene id: 42514:xkrx
uniprot id: A0A3B4E6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:LOC108433092
gene id: 42514:LOC108433092
uniprot id: A0A3B4DQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Nucleus

42514:nr2e3
gene id: 42514:nr2e3
uniprot id: A0A3B4DI14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:LOC108424220
gene id: 42514:LOC108424220
uniprot id: A0A3B4D6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

42514:LOC108411830
gene id: 42514:LOC108411830
uniprot id: A0A3B4DZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

42514:map1lc3b
gene id: 42514:map1lc3b
uniprot id: A0A3B4BTC4
names: Similarity
messages: Belongs to the ATG8 family.

42514:cnksr1
gene id: 42514:cnksr1
uniprot id: A0A3B4DM45
names: Similarity
messages: Belongs to the CNKSR family.

42514:ypel2a
gene id: 42514:ypel2a
uniprot id: A0A3B4CCK3
names: Similarity
messages: Belongs to the yippee family.

42514:LOC108436872
gene id: 42514:LOC108436872
uniprot id: A0A3B4CPF3
names: Subcellular Location Annotation
messages: Membrane

42514:gall
gene id: 42514:gall
uniprot id: A0A3B4BSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Secreted

42514:mybl1
gene id: 42514:mybl1
uniprot id: A0A3B4CYR4
names: Subcellular Location Annotation
messages: Nucleus

42514:nup98
gene id: 42514:nup98
uniprot id: A0A3B4DYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

42514:LOC108420818
gene id: 42514:LOC108420818
uniprot id: A0A3B4C6G8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108438075
gene id: 42514:LOC108438075
uniprot id: A0A3B4DRM2
names: Subcellular Location Annotation
messages: Membrane

42514:etfb
gene id: 42514:etfb
uniprot id: A0A3B4BPI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

42514:LOC108430714
gene id: 42514:LOC108430714
uniprot id: A0A3B4CHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:ppdpfa
gene id: 42514:ppdpfa
uniprot id: A0A3B4BRG2
names: Similarity
messages: Belongs to the PPDPF family.

42514:psma4
gene id: 42514:psma4
uniprot id: A0A3B4DBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

42514:fgf19
gene id: 42514:fgf19
uniprot id: A0A3B4EDE6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:mafb
gene id: 42514:mafb
uniprot id: A0A3B4E2L5
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

42514:LOC108442757
gene id: 42514:LOC108442757
uniprot id: A0A3B4DF97
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108410485
gene id: 42514:LOC108410485
uniprot id: A0A3B4BTX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:banf1
gene id: 42514:banf1
uniprot id: A0A3B4DRR7
names: Subcellular Location Annotation
messages: Nucleus

42514:imp4
gene id: 42514:imp4
uniprot id: A0A3B4C0V2
names: Subcellular Location Annotation
messages: nucleolus

42514:dtx2
gene id: 42514:dtx2
uniprot id: A0A3B4CH37
uniprot id: A0A3B4CJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

42514:tuba8l2
gene id: 42514:tuba8l2
uniprot id: A0A3B4CLX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

42514:jagn1a
gene id: 42514:jagn1a
uniprot id: A0A3B4BMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:myorg
gene id: 42514:myorg
uniprot id: A0A3B4D5V3
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

42514:LOC108436658
gene id: 42514:LOC108436658
uniprot id: A0A3B4EIN2
names: Similarity
messages: Belongs to the apolipoprotein L family.

42514:tmx2a
gene id: 42514:tmx2a
uniprot id: A0A3B4D994
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

42514:LOC108416588
gene id: 42514:LOC108416588
uniprot id: A0A3B4BTX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:avpr2aa
gene id: 42514:avpr2aa
uniprot id: A0A3B4EB67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108429189
gene id: 42514:LOC108429189
uniprot id: A0A3B4CCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

42514:trub2
gene id: 42514:trub2
uniprot id: A0A3B4E4B0
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

42514:LOC108429002
gene id: 42514:LOC108429002
uniprot id: A0A3B4CTQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

42514:nog1
gene id: 42514:nog1
uniprot id: A0A3B4CMG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

42514:agpat3
gene id: 42514:agpat3
uniprot id: A0A3B4EI64
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:btg2
gene id: 42514:btg2
uniprot id: A0A3B4EHF9
names: Similarity
messages: Belongs to the BTG family.

42514:scdb
gene id: 42514:scdb
uniprot id: A0A3B4DKP6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

42514:ngfb
gene id: 42514:ngfb
uniprot id: A0A3B4BU23
names: Similarity
messages: Belongs to the NGF-beta family.

42514:LOC108411616
gene id: 42514:LOC108411616
uniprot id: A0A3B4EDB8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:ghitm
gene id: 42514:ghitm
uniprot id: A0A3B4CNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

42514:smo
gene id: 42514:smo
uniprot id: A0A3B4BU24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:tet2
gene id: 42514:tet2
uniprot id: A0A3B4EJ73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

42514:tns2a
gene id: 42514:tns2a
uniprot id: A0A3B4DBM5
uniprot id: A0A3B4DEC3
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

42514:LOC108432353
gene id: 42514:LOC108432353
uniprot id: A0A3B4CP78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

42514:foxa3
gene id: 42514:foxa3
uniprot id: A0A3B4DYS9
names: Subcellular Location Annotation
messages: Nucleus

42514:pcyt1ba
gene id: 42514:pcyt1ba
uniprot id: A0A3B4EDB1
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

42514:aqp4
gene id: 42514:aqp4
uniprot id: A0A3B4DCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:LOC108440010
gene id: 42514:LOC108440010
uniprot id: A0A3B4D156
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:plppr2a
gene id: 42514:plppr2a
uniprot id: A0A3B4BTV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:scamp2
gene id: 42514:scamp2
uniprot id: A0A3B4EHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

42514:pigb
gene id: 42514:pigb
uniprot id: A0A3B4EH99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

42514:LOC108438080
gene id: 42514:LOC108438080
uniprot id: A0A3B4DQ75
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:prss12
gene id: 42514:prss12
uniprot id: A0A3B4BXZ0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations.
messages: Secreted

42514:inpp4aa
gene id: 42514:inpp4aa
uniprot id: A0A3B4DMX3
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

42514:tnfaip3
gene id: 42514:tnfaip3
uniprot id: A0A3B4D665
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:ube2ka
gene id: 42514:ube2ka
uniprot id: A0A3B4D0J7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:cpt2
gene id: 42514:cpt2
uniprot id: A0A3B4D7H0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

42514:si:ch211-184m13.4
gene id: 42514:si:ch211-184m13.4
uniprot id: A0A3B4CZ49
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:impact
gene id: 42514:impact
uniprot id: A0A3B4D019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

42514:LOC108434887
gene id: 42514:LOC108434887
uniprot id: A0A3B4C3I5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:LOC108436939
gene id: 42514:LOC108436939
uniprot id: A0A3B4DX36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

42514:ilf3a
gene id: 42514:ilf3a
uniprot id: A0A3B4DLF2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:LOC108432803
gene id: 42514:LOC108432803
uniprot id: A0A3B4CYE2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:kcnq5b
gene id: 42514:kcnq5b
uniprot id: A0A3B4BXX9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:LOC108426312
gene id: 42514:LOC108426312
uniprot id: A0A3B4DRN1
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

42514:cdc42l
gene id: 42514:cdc42l
uniprot id: A0A3B4DSG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

42514:si:dkey-1h24.6
gene id: 42514:si:dkey-1h24.6
uniprot id: A0A3B4DYA1
names: Subcellular Location Annotation
messages: Membrane

42514:pcolce2b
gene id: 42514:pcolce2b
uniprot id: A0A3B4DHY8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:hnrnpd
gene id: 42514:hnrnpd
uniprot id: A0A3B4CFL4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:myf5
gene id: 42514:myf5
uniprot id: A0A3B4C810
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

42514:hcrt
gene id: 42514:hcrt
uniprot id: A0A0F6NC03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the orexin family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Synapse
messages: Vesicle

42514:clrn2
gene id: 42514:clrn2
uniprot id: A0A3B4EQM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

42514:pcolcea
gene id: 42514:pcolcea
uniprot id: A0A3B4DHY0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:lzts2b
gene id: 42514:lzts2b
uniprot id: A0A3B4CWD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

42514:esrrb
gene id: 42514:esrrb
uniprot id: A0A3B4BUL9
uniprot id: A0A3B4BXR3
uniprot id: A0A3B4DNB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

42514:f13a1b
gene id: 42514:f13a1b
uniprot id: A0A3B4DC26
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

42514:LOC108424798
gene id: 42514:LOC108424798
uniprot id: A0A3B4EPJ1
names: Similarity
messages: Belongs to the MS4A family.

42514:poc5
gene id: 42514:poc5
uniprot id: A0A3B4CBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

42514:prlrb
gene id: 42514:prlrb
uniprot id: A0A3B4ERR7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

42514:LOC108424884
gene id: 42514:LOC108424884
uniprot id: A0A3B4D5P1
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: cell cortex
messages: cytoskeleton

42514:crbn
gene id: 42514:crbn
uniprot id: A0A3B4E2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

42514:slc26a2
gene id: 42514:slc26a2
uniprot id: A0A3B4D2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

42514:rack1
gene id: 42514:rack1
uniprot id: A0A3B4BQN9
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

42514:rpl13a
gene id: 42514:rpl13a
uniprot id: A0A3B4DAJ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

42514:cxxc1b
gene id: 42514:cxxc1b
uniprot id: A0A3B4BY54
names: Subcellular Location Annotation
messages: Nucleus

42514:tmprss5
gene id: 42514:tmprss5
uniprot id: A0A3B4BRU8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:fxr2
gene id: 42514:fxr2
uniprot id: A0A3B4C9N5
names: Similarity
messages: Belongs to the FMR1 family.

42514:evlb
gene id: 42514:evlb
uniprot id: A0A3B4CTD1
uniprot id: A0A3B4E674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: lamellipodium
messages: stress fiber

42514:cnot9
gene id: 42514:cnot9
uniprot id: A0A3B4EB04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

42514:si:ch73-287m6.1
gene id: 42514:si:ch73-287m6.1
uniprot id: A0A3B4BS92
names: Similarity
messages: Belongs to the RIMBP family.

42514:pole2
gene id: 42514:pole2
uniprot id: A0A3B4C7L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

42514:nav3
gene id: 42514:nav3
uniprot id: A0A3B4C4F7
uniprot id: A0A3B4DWE9
names: Similarity
messages: Belongs to the Nav/unc-53 family.

42514:mdfi
gene id: 42514:mdfi
uniprot id: A0A3B4DT57
names: Similarity
messages: Belongs to the MDFI family.

42514:gng10
gene id: 42514:gng10
uniprot id: A0A3B4EKM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:reep3b
gene id: 42514:reep3b
uniprot id: A0A3B4CPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

42514:hspb1
gene id: 42514:hspb1
uniprot id: A0A3B4BXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

42514:hspb12
gene id: 42514:hspb12
uniprot id: A0A3B4DH98
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:plpp2a
gene id: 42514:plpp2a
uniprot id: A0A3B4EGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:im:6904045
gene id: 42514:im:6904045
uniprot id: A0A3B4C6Q8
names: Similarity
messages: Belongs to the NATD1 family.

42514:LOC108414035
gene id: 42514:LOC108414035
uniprot id: A0A3B4BL09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

42514:tspo
gene id: 42514:tspo
uniprot id: A0A3B4CG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

42514:magi3a
gene id: 42514:magi3a
uniprot id: A0A3B4DW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:LOC108441744
gene id: 42514:LOC108441744
uniprot id: A0A3B4CQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

42514:LOC108415761
gene id: 42514:LOC108415761
uniprot id: A0A3B4DBZ2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108428399
gene id: 42514:LOC108428399
uniprot id: A0A3B4E7D4
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

42514:si:ch211-202p1.5
gene id: 42514:si:ch211-202p1.5
uniprot id: A0A3B4D8Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

42514:pik3r1
gene id: 42514:pik3r1
uniprot id: A0A3B4DDM2
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

42514:bace2
gene id: 42514:bace2
uniprot id: A0A3B4DVD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane

42514:fam221a
gene id: 42514:fam221a
uniprot id: A0A3B4BR67
names: Similarity
messages: Belongs to the FAM221 family.

42514:draxin
gene id: 42514:draxin
uniprot id: A0A3B4EH16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

42514:dusp1
gene id: 42514:dusp1
uniprot id: A0A3B4E7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

42514:rpe
gene id: 42514:rpe
uniprot id: A0A3B4DJT3
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

42514:hmgcra
gene id: 42514:hmgcra
uniprot id: A0A3B4DA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

42514:tmem192
gene id: 42514:tmem192
uniprot id: A0A3B4DIA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

42514:uckl1a
gene id: 42514:uckl1a
uniprot id: A0A3B4C5X2
uniprot id: A0A3B4DV77
names: Similarity
messages: Belongs to the uridine kinase family.

42514:ptbp1b
gene id: 42514:ptbp1b
uniprot id: A0A3B4D1A1
names: Subcellular Location Annotation
messages: Nucleus

42514:atp5pb
gene id: 42514:atp5pb
uniprot id: A0A3B4EEP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

42514:naprt
gene id: 42514:naprt
uniprot id: A0A3B4DKI8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

42514:cd151l
gene id: 42514:cd151l
uniprot id: A0A3B4DFY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:phox2bb
gene id: 42514:phox2bb
uniprot id: A0A3B4CYF5
names: Subcellular Location Annotation
messages: Nucleus

42514:dars2
gene id: 42514:dars2
uniprot id: A0A3B4DNY8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

42514:xgb
gene id: 42514:xgb
uniprot id: A0A3B4CTW6
names: Similarity
messages: Belongs to the globin family.

42514:spag9b
gene id: 42514:spag9b
uniprot id: A0A3B4BUB9
uniprot id: A0A3B4DI90
names: Similarity
messages: Belongs to the JIP scaffold family.

42514:dxo
gene id: 42514:dxo
uniprot id: A0A3B4CJA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

42514:cited1
gene id: 42514:cited1
uniprot id: A0A3B4BWG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

42514:LOC108439206
gene id: 42514:LOC108439206
uniprot id: A0A3B4DRM0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

42514:klc4
gene id: 42514:klc4
uniprot id: A0A3B4BZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

42514:tasora
gene id: 42514:tasora
uniprot id: A0A3B4EM89
uniprot id: A0A3B4EP80
names: Similarity
messages: Belongs to the TASOR family.

42514:runx2a
gene id: 42514:runx2a
uniprot id: A0A3B4CSK6
uniprot id: A0A3B4E7Y7
names: Subcellular Location Annotation
messages: Nucleus

42514:zgc:171566
gene id: 42514:zgc:171566
uniprot id: A0A3B4D0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

42514:ing5a
gene id: 42514:ing5a
uniprot id: A0A3B4CVK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

42514:pias4a
gene id: 42514:pias4a
uniprot id: A0A3B4CIW3
names: Similarity
messages: Belongs to the PIAS family.

42514:LOC108425702
gene id: 42514:LOC108425702
uniprot id: A0A3B4DZN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:cers6
gene id: 42514:cers6
uniprot id: A0A3B4D093
uniprot id: A0A3B4EFU8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

42514:ada2a
gene id: 42514:ada2a
uniprot id: A0A3B4BXA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

42514:coro7
gene id: 42514:coro7
uniprot id: A0A3B4C240
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Cytoplasmic vesicle
messages: F-actin regulator involved in anterograde Golgi to endosome transport: upon ubiquitination via 'Lys-33'-linked ubiquitin chains by the BCR(KLHL20) E3 ubiquitin ligase complex, interacts with EPS15 and localizes to the trans-Golgi network, where it promotes actin polymerization, thereby facilitating post-Golgi trafficking. May play a role in the maintenance of the Golgi apparatus morphology.
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicle
messages: cytosol
messages: trans-Golgi network

42514:LOC108443684
gene id: 42514:LOC108443684
uniprot id: A0A3B4DP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

42514:lbx1a
gene id: 42514:lbx1a
uniprot id: A0A3B4DMD5
names: Subcellular Location Annotation
messages: Nucleus

42514:efna1b
gene id: 42514:efna1b
uniprot id: A0A3B4ELT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:grin2ab
gene id: 42514:grin2ab
uniprot id: A0A3B4DZI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

42514:prdm12b
gene id: 42514:prdm12b
uniprot id: A0A3B4D3N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

42514:btbd10a
gene id: 42514:btbd10a
uniprot id: A0A3B4D7W1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:crot
gene id: 42514:crot
uniprot id: A0A3B4E347
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

42514:lum
gene id: 42514:lum
uniprot id: A0A3B4DF52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

42514:LOC108425220
gene id: 42514:LOC108425220
uniprot id: A0A3B4C4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Lysosome
messages: cytosol
messages: extracellular exosome

42514:sema4e
gene id: 42514:sema4e
uniprot id: A0A3B4DUL8
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dnajc22
gene id: 42514:dnajc22
uniprot id: A0A3B4D473
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

42514:fam199x
gene id: 42514:fam199x
uniprot id: A0A3B4D030
names: Similarity
messages: Belongs to the FAM199 family.

42514:castor1
gene id: 42514:castor1
uniprot id: A0A3B4EFU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GATS family.
messages: cytosol

42514:hesx1
gene id: 42514:hesx1
uniprot id: A0A3B4ENI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

42514:LOC108433903
gene id: 42514:LOC108433903
uniprot id: A0A3B4D9M5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

42514:ints3
gene id: 42514:ints3
uniprot id: A0A3B4DCC5
names: Similarity
messages: Belongs to the Integrator subunit 3 family.

42514:tll1
gene id: 42514:tll1
uniprot id: A0A3B4C6D0
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108440969
gene id: 42514:LOC108440969
uniprot id: A0A3B4DUT7
names: Similarity
messages: Belongs to the intermediate filament family.

42514:hip1rb
gene id: 42514:hip1rb
uniprot id: A0A3B4EA63
names: Similarity
messages: Belongs to the SLA2 family.

42514:chst7
gene id: 42514:chst7
uniprot id: A0A3B4DTV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:LOC108432121
gene id: 42514:LOC108432121
uniprot id: A0A3B4DIA0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:nab2
gene id: 42514:nab2
uniprot id: A0A3B4BUX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

42514:fgf1b
gene id: 42514:fgf1b
uniprot id: A0A3B4EJM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

42514:adss1
gene id: 42514:adss1
uniprot id: A0A3B4CTF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

42514:jak2b
gene id: 42514:jak2b
uniprot id: A0A3B4EM87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

42514:LOC108441182
gene id: 42514:LOC108441182
uniprot id: A0A3B4CUX3
uniprot id: A0A3B4E8F9
uniprot id: A0A3B4E8I8
uniprot id: A0A3B4EAQ1
uniprot id: A0A3B4EC60
uniprot id: A0A3B4ECE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

42514:ptger2b
gene id: 42514:ptger2b
uniprot id: A0A3B4EMI2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:alox5a
gene id: 42514:alox5a
uniprot id: A0A3B4DA59
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:si:ch211-149k23.9
gene id: 42514:si:ch211-149k23.9
uniprot id: A0A3B4E672
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

42514:gask1a
gene id: 42514:gask1a
uniprot id: A0A3B4CYC4
names: Similarity
messages: Belongs to the GASK family.

42514:anapc2
gene id: 42514:anapc2
uniprot id: A0A3B4DC96
names: Similarity
messages: Belongs to the cullin family.

42514:d2hgdh
gene id: 42514:d2hgdh
uniprot id: A0A3B4EJ01
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

42514:LOC108442647
gene id: 42514:LOC108442647
uniprot id: A0A3B4DJ84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

42514:rps6ka1
gene id: 42514:rps6ka1
uniprot id: A0A3B4BR94
uniprot id: A0A3B4BRC4
uniprot id: A0A3B4BRC8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

42514:ptges3b
gene id: 42514:ptges3b
uniprot id: A0A3B4C0C7
names: Similarity
messages: Belongs to the p23/wos2 family.

42514:LOC108427431
gene id: 42514:LOC108427431
uniprot id: A0A3B4E1V1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108415447
gene id: 42514:LOC108415447
uniprot id: A0A3B4DDF2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:haus3
gene id: 42514:haus3
uniprot id: A0A3B4EAV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

42514:LOC108433551
gene id: 42514:LOC108433551
uniprot id: A0A3B4CI97
names: Similarity
names: Subcellular Location Annotation
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

42514:dpm2
gene id: 42514:dpm2
uniprot id: A0A3B4DWZ0
uniprot id: A0A3B4DX42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

42514:LOC108431780
gene id: 42514:LOC108431780
uniprot id: A0A3B4CL18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

42514:sigirr
gene id: 42514:sigirr
uniprot id: A0A3B4BQL7
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

42514:slc24a1
gene id: 42514:slc24a1
uniprot id: A0A3B4CF07
uniprot id: A0A3B4E146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

42514:mef2b
gene id: 42514:mef2b
uniprot id: A0A3B4CUH4
names: Subcellular Location Annotation
messages: Nucleus

42514:chrm2a
gene id: 42514:chrm2a
uniprot id: A0A3B4DAW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

42514:pdia7
gene id: 42514:pdia7
uniprot id: A0A3B4DFJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

42514:LOC108410407
gene id: 42514:LOC108410407
uniprot id: A0A3B4EG53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 7B2 family.
messages: Secreted

42514:ago2
gene id: 42514:ago2
uniprot id: A0A3B4EQ06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of dicer1, ago2 and tarbp2. Note that the trimeric RLC/miRLC is also referred to as RISC.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the mRNA specifically by ago2. Binding of RISC to a partially complementary mRNA results in silencing through inhibition of translation, and this is independent of endonuclease activity. The inhibition of translational initiation leads to the accumulation of the affected mRNA in cytoplasmic processing bodies (P-bodies), where mRNA degradation may subsequently occur.
messages: The Piwi domain may perform RNA cleavage by a mechanism similar to that of RNase H. However, while RNase H utilizes a triad of Asp-Asp-Glu (DDE) for metal ion coordination, this protein appears to utilize a triad of Asp-Asp-His (DDH).

42514:eif4enif1
gene id: 42514:eif4enif1
uniprot id: A0A3B4E406
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108442979
gene id: 42514:LOC108442979
uniprot id: A0A3B4CCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

42514:fgd6
gene id: 42514:fgd6
uniprot id: A0A3B4DI35
names: Subcellular Location Annotation
messages: cytoskeleton

42514:LOC108424466
gene id: 42514:LOC108424466
uniprot id: A0A3B4CEM9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:ism2a
gene id: 42514:ism2a
uniprot id: A0A3B4CNF4
names: Similarity
messages: Belongs to the isthmin family.

42514:ube2na
gene id: 42514:ube2na
uniprot id: A0A3B4E3V0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:zfyve28
gene id: 42514:zfyve28
uniprot id: A0A3B4DYW5
uniprot id: A0A3B4E074
names: Similarity
messages: Belongs to the lst-2 family.

42514:vps35l
gene id: 42514:vps35l
uniprot id: A0A3B4DA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

42514:ces3
gene id: 42514:ces3
uniprot id: A0A3B4CIQ6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

42514:adhfe1
gene id: 42514:adhfe1
uniprot id: A0A3B4E9K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

42514:zgc:152863
gene id: 42514:zgc:152863
uniprot id: A0A3B4BVB2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ddx11
gene id: 42514:ddx11
uniprot id: A0A3B4BQM8
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

42514:si:ch1073-335m2.2
gene id: 42514:si:ch1073-335m2.2
uniprot id: A0A3B4DRX0
names: Similarity
messages: Belongs to the RRM Spen family.

42514:mks1
gene id: 42514:mks1
uniprot id: A0A3B4DZ91
names: Subcellular Location Annotation
messages: cilium basal body

42514:LOC108443021
gene id: 42514:LOC108443021
uniprot id: A0A3B4DZP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

42514:gng12a
gene id: 42514:gng12a
uniprot id: A0A3B4EJ52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:LOC108410935
gene id: 42514:LOC108410935
uniprot id: A0A3B4ELR1
names: Similarity
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

42514:LOC108415169
gene id: 42514:LOC108415169
uniprot id: A0A3B4D167
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108429407
gene id: 42514:LOC108429407
uniprot id: A0A3B4D9J0
uniprot id: A0A3B4ELT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

42514:LOC108442482
gene id: 42514:LOC108442482
uniprot id: A0A3B4DW74
names: Subcellular Location Annotation
messages: Cytoplasm

42514:eef1a1a
gene id: 42514:eef1a1a
uniprot id: A0A3B4BVK5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

42514:LOC108415872
gene id: 42514:LOC108415872
uniprot id: A0A3B4D3Q5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108430744
gene id: 42514:LOC108430744
uniprot id: A0A3B4E5Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

42514:LOC108439868
gene id: 42514:LOC108439868
uniprot id: A0A3B4D937
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

42514:mogs
gene id: 42514:mogs
uniprot id: A0A3B4EL95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

42514:zgc:136930
gene id: 42514:zgc:136930
uniprot id: A0A3B4DKS1
names: Similarity
messages: Belongs to the intermediate filament family.

42514:slc5a2
gene id: 42514:slc5a2
uniprot id: A0A3B4EID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:creb1a
gene id: 42514:creb1a
uniprot id: A0A3B4D3X0
names: Subcellular Location Annotation
messages: Nucleus

42514:skila
gene id: 42514:skila
uniprot id: A0A3B4C037
names: Similarity
messages: Belongs to the SKI family.

42514:prok1
gene id: 42514:prok1
uniprot id: A0A3B4DJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

42514:LOC108441468
gene id: 42514:LOC108441468
uniprot id: A0A3B4DRU3
names: Similarity
messages: Belongs to the FAM83 family.

42514:abcc10
gene id: 42514:abcc10
uniprot id: A0A3B4C2F3
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

42514:ano3
gene id: 42514:ano3
uniprot id: A0A3B4BQH7
uniprot id: A0A3B4DJW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

42514:slc6a22.2
gene id: 42514:slc6a22.2
uniprot id: A0A3B4CG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:ube2d4
gene id: 42514:ube2d4
uniprot id: A0A3B4D0J1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:sbf1
gene id: 42514:sbf1
uniprot id: A0A3B4BVW3
uniprot id: A0A3B4DM61
uniprot id: A0A3B4DMA2
uniprot id: A0A3B4DNF8
uniprot id: A0A3B4DNN1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

42514:patl1
gene id: 42514:patl1
uniprot id: A0A3B4CLE9
names: Similarity
messages: Belongs to the PAT1 family.

42514:echdc1
gene id: 42514:echdc1
uniprot id: A0A3B4C2L9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

42514:eef2b
gene id: 42514:eef2b
uniprot id: A0A3B4D9Q3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

42514:tomm5
gene id: 42514:tomm5
uniprot id: A0A3B4E9W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:tekt4
gene id: 42514:tekt4
uniprot id: A0A3B4C3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

42514:stk11
gene id: 42514:stk11
uniprot id: A0A3B4EGQ5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

42514:mrpl17
gene id: 42514:mrpl17
uniprot id: A0A3B4D960
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

42514:rnaseh2a
gene id: 42514:rnaseh2a
uniprot id: A0A3B4CUE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

42514:LOC108442082
gene id: 42514:LOC108442082
uniprot id: A0A3B4BMJ8
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

42514:selenoo1
gene id: 42514:selenoo1
uniprot id: A0A3B4E9B8
names: Similarity
messages: Belongs to the SELO family.

42514:hspa4b
gene id: 42514:hspa4b
uniprot id: A0A3B4DQ12
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:eif5a
gene id: 42514:eif5a
uniprot id: A0A3B4BU69
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

42514:olfml2bb
gene id: 42514:olfml2bb
uniprot id: A0A3B4E941
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108442268
gene id: 42514:LOC108442268
uniprot id: A0A3B4D0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

42514:ccna2
gene id: 42514:ccna2
uniprot id: A0A3B4D9A6
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

42514:bscl2
gene id: 42514:bscl2
uniprot id: A0A3B4BY56
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:rnasekb
gene id: 42514:rnasekb
uniprot id: A0A3B4BWB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane

42514:si:ch211-232b12.5
gene id: 42514:si:ch211-232b12.5
uniprot id: A0A3B4DNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

42514:aqp12
gene id: 42514:aqp12
uniprot id: A0A3B4CZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

42514:LOC108440592
gene id: 42514:LOC108440592
uniprot id: A0A3B4EC55
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

42514:slc25a1b
gene id: 42514:slc25a1b
uniprot id: A0A3B4C6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:park7
gene id: 42514:park7
uniprot id: A0A3B4EMU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

42514:wscd1b
gene id: 42514:wscd1b
uniprot id: A0A3B4E003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

42514:pdpr
gene id: 42514:pdpr
uniprot id: A0A3B4ELQ0
names: Similarity
messages: Belongs to the GcvT family.

42514:slain2
gene id: 42514:slain2
uniprot id: A0A3B4BWG6
uniprot id: A0A3B4BZT1
uniprot id: A0A3B4DLR2
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

42514:gja1a
gene id: 42514:gja1a
uniprot id: A0A3B4EBA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:cldn5b
gene id: 42514:cldn5b
uniprot id: A0A3B4BSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:zgc:113531
gene id: 42514:zgc:113531
uniprot id: A0A3B4DLU1
names: Subcellular Location Annotation
messages: Synapse

42514:LOC108443936
gene id: 42514:LOC108443936
uniprot id: A0A3B4EJK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

42514:abi1b
gene id: 42514:abi1b
uniprot id: A0A3B4CH55
uniprot id: A0A3B4CIS3
uniprot id: A0A3B4E3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

42514:fam219aa
gene id: 42514:fam219aa
uniprot id: A0A3B4EJD9
names: Similarity
messages: Belongs to the FAM219 family.

42514:cpne1
gene id: 42514:cpne1
uniprot id: A0A3B4BPC0
names: Similarity
messages: Belongs to the copine family.

42514:plpp2b
gene id: 42514:plpp2b
uniprot id: A0A3B4E7C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:mpv17
gene id: 42514:mpv17
uniprot id: A0A3B4DCR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

42514:tmem145
gene id: 42514:tmem145
uniprot id: A0A3B4ELI0
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108434338
gene id: 42514:LOC108434338
uniprot id: A0A3B4BPT1
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

42514:LOC108433259
gene id: 42514:LOC108433259
uniprot id: A0A3B4EGH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

42514:asrgl1
gene id: 42514:asrgl1
uniprot id: A0A3B4BUH2
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

42514:polr1d
gene id: 42514:polr1d
uniprot id: A0A3B4BYI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

42514:fgf16
gene id: 42514:fgf16
uniprot id: A0A3B4E9R6
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:LOC108435466
gene id: 42514:LOC108435466
uniprot id: A0A3B4DFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:rpl8
gene id: 42514:rpl8
uniprot id: A0A3B4CUV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

42514:pvalb3
gene id: 42514:pvalb3
uniprot id: A0A3B4DP32
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

42514:atl1
gene id: 42514:atl1
uniprot id: A0A3B4C6M1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

42514:ndufab1a
gene id: 42514:ndufab1a
uniprot id: A0A3B4E0F5
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

42514:soga1
gene id: 42514:soga1
uniprot id: A0A3B4BY82
names: Similarity
messages: Belongs to the SOGA family.

42514:LOC108439433
gene id: 42514:LOC108439433
uniprot id: A0A3B4ECU0
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

42514:rpl10a
gene id: 42514:rpl10a
uniprot id: A0A3B4CLH3
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

42514:slx4
gene id: 42514:slx4
uniprot id: A0A3B4E5F6
names: Similarity
messages: Belongs to the SLX4 family.

42514:cdk19
gene id: 42514:cdk19
uniprot id: A0A3B4C535
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:scpep1
gene id: 42514:scpep1
uniprot id: A0A3B4CCC0
names: Similarity
messages: Belongs to the peptidase S10 family.

42514:pdk3b
gene id: 42514:pdk3b
uniprot id: A0A3B4CBB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

42514:LOC108436790
gene id: 42514:LOC108436790
uniprot id: A0A3B4CWA9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:rpl13
gene id: 42514:rpl13
uniprot id: A0A3B4CB31
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

42514:clstn1
gene id: 42514:clstn1
uniprot id: A0A3B4CV50
uniprot id: A0A3B4CX92
uniprot id: A0A3B4EDQ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

42514:si:ch1073-416d2.3
gene id: 42514:si:ch1073-416d2.3
uniprot id: A0A3B4DMV1
names: Similarity
messages: Belongs to the serpin family.

42514:nppb
gene id: 42514:nppb
uniprot id: A0A3B4EJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

42514:gabrg2
gene id: 42514:gabrg2
uniprot id: A0A3B4D029
uniprot id: A0A3B4D0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:LOC108441546
gene id: 42514:LOC108441546
uniprot id: A0A3B4BT62
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:rab38a
gene id: 42514:rab38a
uniprot id: A0A3B4D8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

42514:trmt112
gene id: 42514:trmt112
uniprot id: A0A3B4EJQ2
names: Similarity
messages: Belongs to the TRM112 family.

42514:LOC108410534
gene id: 42514:LOC108410534
uniprot id: A0A3B4EBZ1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:phkg1a
gene id: 42514:phkg1a
uniprot id: A0A3B4BNL5
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

42514:LOC108430561
gene id: 42514:LOC108430561
uniprot id: A0A3B4D4A4
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108428580
gene id: 42514:LOC108428580
uniprot id: A0A3B4C192
uniprot id: A0A3B4DQF0
names: Similarity
messages: Belongs to the PAIP2 family.

42514:ccne2
gene id: 42514:ccne2
uniprot id: A0A3B4CZX7
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

42514:tspan7
gene id: 42514:tspan7
uniprot id: A0A3B4CRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:eif4a3
gene id: 42514:eif4a3
uniprot id: A0A3B4DJ65
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:gtf2e2
gene id: 42514:gtf2e2
uniprot id: A0A3B4EK25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

42514:cfap299
gene id: 42514:cfap299
uniprot id: A0A3B4E7V4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

42514:cct6a
gene id: 42514:cct6a
uniprot id: A0A3B4CMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

42514:irf2a
gene id: 42514:irf2a
uniprot id: A0A3B4C7N8
uniprot id: A0A3B4DYE1
names: Caution
names: Similarity
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:eloal
gene id: 42514:eloal
uniprot id: A0A3B4D3H3
names: Subcellular Location Annotation
messages: Nucleus

42514:gad1b
gene id: 42514:gad1b
uniprot id: A0A3B4C0Y2
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

42514:myo5b
gene id: 42514:myo5b
uniprot id: A0A3B4E2G0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:msto1
gene id: 42514:msto1
uniprot id: A0A3B4BSB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

42514:dohh
gene id: 42514:dohh
uniprot id: A0A3B4CBC1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

42514:LOC108413813
gene id: 42514:LOC108413813
uniprot id: A0A3B4BTX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:LOC108432860
gene id: 42514:LOC108432860
uniprot id: A0A3B4D0F9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108411357
gene id: 42514:LOC108411357
uniprot id: A0A3B4BNB5
names: Similarity
messages: Belongs to the CLCR family.

42514:brf2
gene id: 42514:brf2
uniprot id: A0A3B4CIG4
names: Similarity
messages: Belongs to the TFIIB family.

42514:btk
gene id: 42514:btk
uniprot id: A0A3B4E5P4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:itpk1b
gene id: 42514:itpk1b
uniprot id: A0A3B4E5I4
names: Similarity
messages: Belongs to the ITPK1 family.

42514:LOC108426176
gene id: 42514:LOC108426176
uniprot id: A0A3B4DXN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

42514:cacna2d2b
gene id: 42514:cacna2d2b
uniprot id: A0A3B4DIX5
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

42514:stim1b
gene id: 42514:stim1b
uniprot id: A0A3B4DZ26
uniprot id: A0A3B4E0C5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:kcnj19a
gene id: 42514:kcnj19a
uniprot id: A0A3B4BTR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

42514:LOC108412264
gene id: 42514:LOC108412264
uniprot id: A0A3B4CFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

42514:entpd6
gene id: 42514:entpd6
uniprot id: A0A3B4EHS2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:pbrm1
gene id: 42514:pbrm1
uniprot id: A0A3B4C7W0
names: Subcellular Location Annotation
messages: Nucleus

42514:plin3
gene id: 42514:plin3
uniprot id: A0A3B4EM50
names: Similarity
messages: Belongs to the perilipin family.

42514:hcn3
gene id: 42514:hcn3
uniprot id: A0A3B4CGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

42514:alas1
gene id: 42514:alas1
uniprot id: A0A3B4BLU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

42514:nr4a2b
gene id: 42514:nr4a2b
uniprot id: A0A3B4E407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

42514:prpf18
gene id: 42514:prpf18
uniprot id: A0A3B4EED4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

42514:cd164l2
gene id: 42514:cd164l2
uniprot id: A0A3B4D813
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

42514:tafa4b
gene id: 42514:tafa4b
uniprot id: A0A3B4DZY8
names: Similarity
messages: Belongs to the TAFA family.

42514:cnot3a
gene id: 42514:cnot3a
uniprot id: A0A3B4CM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

42514:utp15
gene id: 42514:utp15
uniprot id: A0A3B4D832
names: Subcellular Location Annotation
messages: nucleolus

42514:rpl36a
gene id: 42514:rpl36a
uniprot id: A0A3B4BT32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Cytoplasm

42514:zdhhc8a
gene id: 42514:zdhhc8a
uniprot id: A0A3B4CTI0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:xrn2
gene id: 42514:xrn2
uniprot id: A0A3B4C115
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

42514:fam102aa
gene id: 42514:fam102aa
uniprot id: A0A3B4DJF1
names: Similarity
messages: Belongs to the FAM102 family.

42514:gem
gene id: 42514:gem
uniprot id: A0A3B4DIQ3
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

42514:eny2
gene id: 42514:eny2
uniprot id: A0A3B4DRA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

42514:adcyap1r1b
gene id: 42514:adcyap1r1b
uniprot id: A0A3B4BYA5
names: Subcellular Location Annotation
messages: Membrane

42514:esf1
gene id: 42514:esf1
uniprot id: A0A3B4CCC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

42514:mpp1
gene id: 42514:mpp1
uniprot id: A0A3B4BYZ1
names: Similarity
messages: Belongs to the MAGUK family.

42514:c8h4orf47
gene id: 42514:c8h4orf47
uniprot id: A0A3B4D2M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: centrosome

42514:LOC108432931
gene id: 42514:LOC108432931
uniprot id: A0A3B4DFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:tamm41
gene id: 42514:tamm41
uniprot id: A0A3B4BR87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

42514:arvcfa
gene id: 42514:arvcfa
uniprot id: A0A3B4CSZ3
uniprot id: A0A3B4CTM0
names: Similarity
messages: Belongs to the beta-catenin family.

42514:calr3b
gene id: 42514:calr3b
uniprot id: A0A3B4EFR7
names: Similarity
messages: Belongs to the calreticulin family.

42514:LOC108432821
gene id: 42514:LOC108432821
uniprot id: A0A3B4CWL3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:adam9
gene id: 42514:adam9
uniprot id: A0A3B4CAQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:rnf13
gene id: 42514:rnf13
uniprot id: A0A3B4CFG5
names: Subcellular Location Annotation
messages: Membrane

42514:abhd2a
gene id: 42514:abhd2a
uniprot id: A0A3B4DW67
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

42514:fbxo25
gene id: 42514:fbxo25
uniprot id: A0A3B4ELS5
uniprot id: A0A3B4ENU7
names: Subcellular Location Annotation
messages: Nucleus

42514:setdb1a
gene id: 42514:setdb1a
uniprot id: A0A3B4CGP7
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

42514:aplnra
gene id: 42514:aplnra
uniprot id: A0A3B4C4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:aldob
gene id: 42514:aldob
uniprot id: A0A3B4D6P7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

42514:slc66a1
gene id: 42514:slc66a1
uniprot id: A0A3B4E147
names: Subcellular Location Annotation
messages: Membrane

42514:meox2b
gene id: 42514:meox2b
uniprot id: A0A3B4BUW8
names: Subcellular Location Annotation
messages: Nucleus

42514:ano7
gene id: 42514:ano7
uniprot id: A0A3B4C307
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

42514:dgki
gene id: 42514:dgki
uniprot id: A0A3B4EMX3
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

42514:arhgdig
gene id: 42514:arhgdig
uniprot id: A0A3B4CYG6
uniprot id: A0A3B4D0L7
names: Similarity
messages: Belongs to the Rho GDI family.

42514:upf3a
gene id: 42514:upf3a
uniprot id: A0A3B4CQM9
uniprot id: A0A3B4E5M3
names: Similarity
messages: Belongs to the RENT3 family.

42514:rwdd3
gene id: 42514:rwdd3
uniprot id: A0A3B4CUW8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:nr1d2a
gene id: 42514:nr1d2a
uniprot id: A0A3B4D5R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

42514:spen
gene id: 42514:spen
uniprot id: A0A3B4EA51
names: Similarity
messages: Belongs to the RRM Spen family.

42514:snupn
gene id: 42514:snupn
uniprot id: A0A3B4EK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

42514:kcnd1
gene id: 42514:kcnd1
uniprot id: A0A3B4D7R2
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

42514:cand2
gene id: 42514:cand2
uniprot id: A0A3B4D4M3
names: Similarity
messages: Belongs to the CAND family.

42514:cltb
gene id: 42514:cltb
uniprot id: A0A3B4C6X6
uniprot id: A0A3B4DVW3
uniprot id: A0A3B4DW61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

42514:ssh1a
gene id: 42514:ssh1a
uniprot id: A0A3B4C4N5
uniprot id: A0A3B4DQ00
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

42514:mycla
gene id: 42514:mycla
uniprot id: A0A3B4BZM6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

42514:si:ch211-26b3.4
gene id: 42514:si:ch211-26b3.4
uniprot id: A0A3B4DKG3
names: Similarity
messages: Belongs to the CNKSR family.

42514:slc25a10
gene id: 42514:slc25a10
uniprot id: A0A3B4CDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:LOC108412361
gene id: 42514:LOC108412361
uniprot id: A0A3B4DUK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:LOC108436631
gene id: 42514:LOC108436631
uniprot id: A0A3B4EK14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

42514:LOC108429792
gene id: 42514:LOC108429792
uniprot id: A0A3B4DNN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

42514:olfml2a
gene id: 42514:olfml2a
uniprot id: A0A3B4C6C2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:chrnb1
gene id: 42514:chrnb1
uniprot id: A0A3B4DSM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:vipb
gene id: 42514:vipb
uniprot id: A0A3B4DK94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted
messages: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

42514:trabd2b
gene id: 42514:trabd2b
uniprot id: A0A3B4CMV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

42514:stk17b
gene id: 42514:stk17b
uniprot id: A0A3B4EN98
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:slc1a6
gene id: 42514:slc1a6
uniprot id: A0A3B4ED17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:prlra
gene id: 42514:prlra
uniprot id: A0A3B4ECI7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

42514:zgc:113149
gene id: 42514:zgc:113149
uniprot id: A0A3B4DH29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

42514:igf1ra
gene id: 42514:igf1ra
uniprot id: A0A3B4C8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:blmh
gene id: 42514:blmh
uniprot id: A0A3B4BWE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

42514:atp5mf
gene id: 42514:atp5mf
uniprot id: A0A3B4CZ13
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

42514:usp32
gene id: 42514:usp32
uniprot id: A0A3B4BYL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Nucleus

42514:nr2f6b
gene id: 42514:nr2f6b
uniprot id: A0A3B4D3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:LOC108438431
gene id: 42514:LOC108438431
uniprot id: A0A3B4ECY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:ttc19
gene id: 42514:ttc19
uniprot id: A0A3B4DCU0
names: Similarity
messages: Belongs to the TTC19 family.

42514:LOC108428089
gene id: 42514:LOC108428089
uniprot id: A0A3B4C2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

42514:tpra
gene id: 42514:tpra
uniprot id: A0A3B4E8X5
names: Similarity
messages: Belongs to the TPR family.

42514:map2k1
gene id: 42514:map2k1
uniprot id: A0A3B4CCA7
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:idh1
gene id: 42514:idh1
uniprot id: A0A3B4EIQ1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

42514:gls2b
gene id: 42514:gls2b
uniprot id: A0A3B4DDG5
uniprot id: A0A3B4DH90
names: Similarity
messages: Belongs to the glutaminase family.

42514:hrh2b
gene id: 42514:hrh2b
uniprot id: A0A3B4D8S9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:kpna3
gene id: 42514:kpna3
uniprot id: A0A3B4D5T6
names: Similarity
messages: Belongs to the importin alpha family.

42514:grpel1
gene id: 42514:grpel1
uniprot id: A0A3B4CEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

42514:slc39a6
gene id: 42514:slc39a6
uniprot id: A0A3B4CT61
names: Subcellular Location Annotation
messages: Membrane

42514:meox1
gene id: 42514:meox1
uniprot id: A0A3B4DKJ5
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108441957
gene id: 42514:LOC108441957
uniprot id: A0A3B4DSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:phgdh
gene id: 42514:phgdh
uniprot id: A0A3B4C5T5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

42514:mbtps1
gene id: 42514:mbtps1
uniprot id: A0A3B4E9M1
names: Similarity
messages: Belongs to the peptidase S8 family.

42514:prl
gene id: 42514:prl
uniprot id: A0A3B4CP36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

42514:LOC108440270
gene id: 42514:LOC108440270
uniprot id: A0A3B4C4X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

42514:elavl1b
gene id: 42514:elavl1b
uniprot id: A0A3B4EHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

42514:zgc:92162
gene id: 42514:zgc:92162
uniprot id: A0A3B4BXV1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

42514:trarg1a
gene id: 42514:trarg1a
uniprot id: A0A3B4BX17
names: Similarity
messages: Belongs to the CD225/Dispanin family.

42514:eno1a
gene id: 42514:eno1a
uniprot id: A0A3B4CR57
names: Similarity
messages: Belongs to the enolase family.

42514:slc7a1a
gene id: 42514:slc7a1a
uniprot id: A0A3B4D4W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:tmem231
gene id: 42514:tmem231
uniprot id: A0A3B4E5K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

42514:slc25a47b
gene id: 42514:slc25a47b
uniprot id: A0A3B4C7W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:gtf2h3
gene id: 42514:gtf2h3
uniprot id: A0A3B4CQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.

42514:hoxb13a
gene id: 42514:hoxb13a
uniprot id: A0A3B4CGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:LOC108434521
gene id: 42514:LOC108434521
uniprot id: A0A3B4EDT3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:eef1a2
gene id: 42514:eef1a2
uniprot id: A0A3B4DJ54
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

42514:hmx4
gene id: 42514:hmx4
uniprot id: A0A3B4C9U1
names: Subcellular Location Annotation
messages: Nucleus

42514:gpatch11
gene id: 42514:gpatch11
uniprot id: A0A3B4DJL6
names: Similarity
messages: Belongs to the GPATCH11 family.

42514:cavin1a
gene id: 42514:cavin1a
uniprot id: A0A3B4CCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

42514:zgc:56235
gene id: 42514:zgc:56235
uniprot id: A0A3B4C646
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

42514:tp53rk
gene id: 42514:tp53rk
uniprot id: A0A3B4BN53
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

42514:kcnv1
gene id: 42514:kcnv1
uniprot id: A0A3B4CXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

42514:ttc39a
gene id: 42514:ttc39a
uniprot id: A0A3B4E4N7
uniprot id: A0A3B4E4U0
names: Similarity
messages: Belongs to the TTC39 family.

42514:LOC108429440
gene id: 42514:LOC108429440
uniprot id: A0A3B4C6I8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:il1rapl1b
gene id: 42514:il1rapl1b
uniprot id: A0A3B4D9M9
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

42514:gfod2
gene id: 42514:gfod2
uniprot id: A0A3B4DHL9
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

42514:cahz
gene id: 42514:cahz
uniprot id: A0A3B4D1A6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:LOC108428970
gene id: 42514:LOC108428970
uniprot id: A0A3B4ECL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

42514:aptx
gene id: 42514:aptx
uniprot id: A0A3B4E321
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

42514:chrna2b
gene id: 42514:chrna2b
uniprot id: A0A3B4D888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:pou2f1b
gene id: 42514:pou2f1b
uniprot id: A0A3B4D2K7
uniprot id: A0A3B4ECD6
uniprot id: A0A3B4EED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

42514:nfasca
gene id: 42514:nfasca
uniprot id: A0A3B4C707
uniprot id: A0A3B4C7K7
uniprot id: A0A3B4C8U3
uniprot id: A0A3B4DWM5
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

42514:LOC108433277
gene id: 42514:LOC108433277
uniprot id: A0A3B4DC38
names: Similarity
messages: Belongs to the peptidase M10A family.

42514:ccnf
gene id: 42514:ccnf
uniprot id: A0A3B4C297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: centriole
messages: perinuclear region

42514:mpdu1b
gene id: 42514:mpdu1b
uniprot id: A0A3B4DAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane

42514:tfdp2
gene id: 42514:tfdp2
uniprot id: A0A3B4C0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:seh1l
gene id: 42514:seh1l
uniprot id: A0A3B4D6Y0
uniprot id: A0A3B4D8C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

42514:slc12a2
gene id: 42514:slc12a2
uniprot id: A0A3B4CNT3
uniprot id: A0A3B4CQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

42514:mepce
gene id: 42514:mepce
uniprot id: A0A3B4E2T1
names: Similarity
messages: Belongs to the methyltransferase superfamily.

42514:fam168b
gene id: 42514:fam168b
uniprot id: A0A3B4D069
names: Similarity
messages: Belongs to the FAM168 family.

42514:LOC108437045
gene id: 42514:LOC108437045
uniprot id: A0A3B4C3Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

42514:gadd45ab
gene id: 42514:gadd45ab
uniprot id: A0A3B4BUD6
names: Similarity
messages: Belongs to the GADD45 family.

42514:avpr1aa
gene id: 42514:avpr1aa
uniprot id: A0A3B4D679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:arap3
gene id: 42514:arap3
uniprot id: A0A3B4D6H0
names: Subcellular Location Annotation
messages: Cytoplasm

42514:tgm2l
gene id: 42514:tgm2l
uniprot id: A0A3B4E1R5
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

42514:ralaa
gene id: 42514:ralaa
uniprot id: A0A3B4BRM3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

42514:gtf2a1l
gene id: 42514:gtf2a1l
uniprot id: A0A3B4CC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

42514:LOC108438015
gene id: 42514:LOC108438015
uniprot id: A0A3B4C4D9
names: Subcellular Location Annotation
messages: Membrane

42514:pus7
gene id: 42514:pus7
uniprot id: A0A3B4DQ60
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

42514:pde3a
gene id: 42514:pde3a
uniprot id: A0A3B4CXD0
uniprot id: A0A3B4EDU0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:LOC108414698
gene id: 42514:LOC108414698
uniprot id: A0A3B4CJD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

42514:thrap3a
gene id: 42514:thrap3a
uniprot id: A0A3B4CGN3
uniprot id: A0A3B4E0G1
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

42514:slc6a17
gene id: 42514:slc6a17
uniprot id: A0A3B4BPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:ctsa
gene id: 42514:ctsa
uniprot id: A0A3B4DAG7
names: Similarity
messages: Belongs to the peptidase S10 family.

42514:ubald2
gene id: 42514:ubald2
uniprot id: A0A3B4EER1
names: Similarity
messages: Belongs to the UBALD family.

42514:tet1
gene id: 42514:tet1
uniprot id: A0A3B4EMD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

42514:pgls
gene id: 42514:pgls
uniprot id: A0A3B4CFD6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

42514:zic2a
gene id: 42514:zic2a
uniprot id: A0A3B4EEZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

42514:pcnx2
gene id: 42514:pcnx2
uniprot id: A0A3B4DF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

42514:pfas
gene id: 42514:pfas
uniprot id: A0A3B4DKZ7
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

42514:ndufb4
gene id: 42514:ndufb4
uniprot id: A0A3B4CY94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

42514:grhl1
gene id: 42514:grhl1
uniprot id: A0A3B4EEI7
names: Subcellular Location Annotation
messages: Nucleus

42514:zgc:153733
gene id: 42514:zgc:153733
uniprot id: A0A3B4C9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

42514:svopl
gene id: 42514:svopl
uniprot id: A0A3B4BUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

42514:gch2
gene id: 42514:gch2
uniprot id: A0A3B4DMS8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

42514:nab1b
gene id: 42514:nab1b
uniprot id: A0A3B4CW58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

42514:glg1b
gene id: 42514:glg1b
uniprot id: A0A3B4D9Y4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

42514:gata2b
gene id: 42514:gata2b
uniprot id: A0A3B4CJM9
names: Subcellular Location Annotation
messages: Nucleus

42514:map3k12
gene id: 42514:map3k12
uniprot id: A0A3B4DTL3
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

42514:sin3ab
gene id: 42514:sin3ab
uniprot id: A0A3B4E0A0
names: Subcellular Location Annotation
messages: Nucleus

42514:ino80db
gene id: 42514:ino80db
uniprot id: A0A3B4BVG8
names: Subcellular Location Annotation
messages: Nucleus

42514:atp1b1a
gene id: 42514:atp1b1a
uniprot id: A0A3B4EM17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

42514:atp2a3
gene id: 42514:atp2a3
uniprot id: A0A3B4C9A5
uniprot id: A0A3B4C9B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

42514:snx8a
gene id: 42514:snx8a
uniprot id: A0A3B4CTJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

42514:LOC108424711
gene id: 42514:LOC108424711
uniprot id: A0A3B4DFM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

42514:slc25a22b
gene id: 42514:slc25a22b
uniprot id: A0A3B4CDS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:si:ch211-132p1.2
gene id: 42514:si:ch211-132p1.2
uniprot id: A0A3B4EBD0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:cdca5
gene id: 42514:cdca5
uniprot id: A0A3B4CZ55
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

42514:lepa
gene id: 42514:lepa
uniprot id: A0A3B4D0N5
names: Similarity
messages: Belongs to the leptin family.

42514:si:ch1073-429i10.1
gene id: 42514:si:ch1073-429i10.1
uniprot id: A0A3B4EAD0
names: Similarity
messages: Belongs to the ERG4/ERG24 family.

42514:cdkn1ba
gene id: 42514:cdkn1ba
uniprot id: A0A3B4DDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

42514:tpi1a
gene id: 42514:tpi1a
uniprot id: A0A3B4DPR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

42514:LOC108440365
gene id: 42514:LOC108440365
uniprot id: A0A3B4DMB4
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

42514:LOC108430889
gene id: 42514:LOC108430889
uniprot id: A0A3B4C5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

42514:hyi
gene id: 42514:hyi
uniprot id: A0A3B4CDQ9
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

42514:LOC108442432
gene id: 42514:LOC108442432
uniprot id: A0A3B4CDA8
names: Similarity
messages: Belongs to the SOGA family.

42514:ets2
gene id: 42514:ets2
uniprot id: A0A3B4CLF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:LOC108441081
gene id: 42514:LOC108441081
uniprot id: A0A3B4D5Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:slc23a2
gene id: 42514:slc23a2
uniprot id: A0A3B4DUN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

42514:rabggta
gene id: 42514:rabggta
uniprot id: A0A3B4CTL2
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

42514:clcn1a
gene id: 42514:clcn1a
uniprot id: A0A3B4ELZ7
names: Subcellular Location Annotation
messages: Membrane

42514:fam131a
gene id: 42514:fam131a
uniprot id: A0A3B4CPG1
names: Similarity
messages: Belongs to the FAM131 family.

42514:gabrb4
gene id: 42514:gabrb4
uniprot id: A0A3B4D333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:pmelb
gene id: 42514:pmelb
uniprot id: A0A3B4CW85
names: Similarity
messages: Belongs to the PMEL/NMB family.

42514:lamc1
gene id: 42514:lamc1
uniprot id: A0A3B4CV35
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

42514:LOC108411388
gene id: 42514:LOC108411388
uniprot id: A0A3B4BM16
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:etv6
gene id: 42514:etv6
uniprot id: A0A3B4BQX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:mycn
gene id: 42514:mycn
uniprot id: A0A3B4CJ11
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX.
messages: Nucleus

42514:cpvl
gene id: 42514:cpvl
uniprot id: A0A3B4BT07
names: Similarity
messages: Belongs to the peptidase S10 family.

42514:adcy8
gene id: 42514:adcy8
uniprot id: A0A3B4E9M7
uniprot id: A0A3B4EBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

42514:tpst1
gene id: 42514:tpst1
uniprot id: A0A3B4C1T9
uniprot id: A0A3B4DNF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

42514:ska1
gene id: 42514:ska1
uniprot id: A0A3B4BVP7
names: Similarity
messages: Belongs to the SKA1 family.

42514:tmem200ca
gene id: 42514:tmem200ca
uniprot id: A0A3B4D409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

42514:dld
gene id: 42514:dld
uniprot id: A0A3B4C4N4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

42514:LOC108423552
gene id: 42514:LOC108423552
uniprot id: A0A3B4EPU1
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

42514:pias4b
gene id: 42514:pias4b
uniprot id: A0A3B4DC22
names: Similarity
messages: Belongs to the PIAS family.

42514:LOC108412671
gene id: 42514:LOC108412671
uniprot id: A0A3B4D9W8
uniprot id: A0A3B4D9Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

42514:LOC108424272
gene id: 42514:LOC108424272
uniprot id: A0A3B4E8S7
names: Subcellular Location Annotation
messages: Nucleus

42514:her1
gene id: 42514:her1
uniprot id: A0A3B4CH41
names: Subunit
messages: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.

42514:mrpl24
gene id: 42514:mrpl24
uniprot id: A0A3B4BS58
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

42514:LOC108432372
gene id: 42514:LOC108432372
uniprot id: A0A3B4CA57
names: Subcellular Location Annotation
messages: Secreted

42514:dhodh
gene id: 42514:dhodh
uniprot id: A0A3B4C6E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

42514:LOC108431249
gene id: 42514:LOC108431249
uniprot id: A0A3B4C9H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:vps26a
gene id: 42514:vps26a
uniprot id: A0A3B4E6N2
names: Similarity
messages: Belongs to the VPS26 family.

42514:mat1a
gene id: 42514:mat1a
uniprot id: A0A3B4E531
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

42514:slc6a3
gene id: 42514:slc6a3
uniprot id: A0A3B4C769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

42514:wfikkn2a
gene id: 42514:wfikkn2a
uniprot id: A0A3B4D6H7
names: Similarity
messages: Belongs to the WFIKKN family.

42514:klc1a
gene id: 42514:klc1a
uniprot id: A0A3B4DF67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

42514:gjb1a
gene id: 42514:gjb1a
uniprot id: A0A3B4CD41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:kcnq2a
gene id: 42514:kcnq2a
uniprot id: A0A3B4D2T8
uniprot id: A0A3B4EEW4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:zgc:162872
gene id: 42514:zgc:162872
uniprot id: A0A3B4D546
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

42514:myoz1b
gene id: 42514:myoz1b
uniprot id: A0A3B4DP28
names: Similarity
messages: Belongs to the myozenin family.

42514:bsk146
gene id: 42514:bsk146
uniprot id: A0A3B4EJS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

42514:slc39a10
gene id: 42514:slc39a10
uniprot id: A0A3B4EN42
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108423901
gene id: 42514:LOC108423901
uniprot id: A0A3B4CDD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

42514:LOC108431997
gene id: 42514:LOC108431997
uniprot id: A0A3B4DQI5
names: Similarity
messages: Belongs to the globin family.

42514:blk
gene id: 42514:blk
uniprot id: A0A3B4EMI4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:LOC108429832
gene id: 42514:LOC108429832
uniprot id: A0A3B4DSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

42514:npm2b
gene id: 42514:npm2b
uniprot id: A0A3B4BSX6
names: Similarity
messages: Belongs to the nucleoplasmin family.

42514:timm8b
gene id: 42514:timm8b
uniprot id: A0A3B4C4J1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

42514:ripor2
gene id: 42514:ripor2
uniprot id: A0A3B4BYX0
uniprot id: A0A3B4DLB5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the RIPOR family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: stereocilium membrane

42514:ogdhl
gene id: 42514:ogdhl
uniprot id: A0A3B4DL78
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

42514:rrh
gene id: 42514:rrh
uniprot id: A0A3B4E0F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:pear1
gene id: 42514:pear1
uniprot id: A0A3B4DVK0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dpyda.1
gene id: 42514:dpyda.1
uniprot id: A0A3B4CZ81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

42514:yipf3
gene id: 42514:yipf3
uniprot id: A0A3B4DUY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
messages: Membrane
messages: cis-Golgi network membrane

42514:mdkb
gene id: 42514:mdkb
uniprot id: A0A3B4DF48
names: Similarity
messages: Belongs to the pleiotrophin family.

42514:dpysl2a
gene id: 42514:dpysl2a
uniprot id: A0A3B4BNB0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

42514:lsm14aa
gene id: 42514:lsm14aa
uniprot id: A0A3B4BNZ1
uniprot id: A0A3B4BPH1
names: Similarity
messages: Belongs to the LSM14 family.

42514:aldh8a1
gene id: 42514:aldh8a1
uniprot id: A0A3B4D8R0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

42514:si:ch211-121a2.4
gene id: 42514:si:ch211-121a2.4
uniprot id: A0A3B4ELG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM205 family.
messages: Membrane

42514:LOC108439955
gene id: 42514:LOC108439955
uniprot id: A0A3B4EJ75
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:gjb9a
gene id: 42514:gjb9a
uniprot id: A0A3B4DZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:elapor1
gene id: 42514:elapor1
uniprot id: A0A3B4CLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELAPOR family.
messages: Cell membrane
messages: Membrane

42514:timp2b
gene id: 42514:timp2b
uniprot id: A0A3B4C7J6
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

42514:ivd
gene id: 42514:ivd
uniprot id: A0A3B4CVP4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

42514:hbp1
gene id: 42514:hbp1
uniprot id: A0A3B4ERG5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

42514:urod
gene id: 42514:urod
uniprot id: A0A3B4CZ42
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

42514:LOC108441923
gene id: 42514:LOC108441923
uniprot id: A0A3B4DRF7
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:mrpl37
gene id: 42514:mrpl37
uniprot id: A0A3B4DDR5
names: Subcellular Location Annotation
messages: Mitochondrion

42514:ajap1
gene id: 42514:ajap1
uniprot id: A0A3B4CPJ5
names: Subcellular Location Annotation
messages: Membrane

42514:hlcs
gene id: 42514:hlcs
uniprot id: A0A3B4CMD3
names: Similarity
messages: Belongs to the biotin--protein ligase family.

42514:tmem120b
gene id: 42514:tmem120b
uniprot id: A0A3B4CGM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

42514:elovl1a
gene id: 42514:elovl1a
uniprot id: A0A3B4D3C1
uniprot id: A0A3B4EGU3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

42514:ep300b
gene id: 42514:ep300b
uniprot id: A0A3B4CMB5
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108425613
gene id: 42514:LOC108425613
uniprot id: A0A3B4CBS1
names: Similarity
messages: Belongs to the HEBP family.

42514:dipk1aa
gene id: 42514:dipk1aa
uniprot id: A0A3B4DD09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

42514:cav3
gene id: 42514:cav3
uniprot id: A0A3B4CJ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

42514:crybb1l3
gene id: 42514:crybb1l3
uniprot id: A0A3B4DLQ8
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:hnrnpc
gene id: 42514:hnrnpc
uniprot id: A0A3B4E7Q7
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

42514:tnfsf11
gene id: 42514:tnfsf11
uniprot id: A0A3B4CI43
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:LOC108443332
gene id: 42514:LOC108443332
uniprot id: A0A3B4D995
names: Subcellular Location Annotation
messages: Cytoplasm

42514:tefa
gene id: 42514:tefa
uniprot id: A0A3B4C2X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

42514:ptch2
gene id: 42514:ptch2
uniprot id: A0A3B4DLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

42514:mau2
gene id: 42514:mau2
uniprot id: A0A3B4EH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

42514:aldh1l1
gene id: 42514:aldh1l1
uniprot id: A0A3B4DDQ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

42514:LOC108431661
gene id: 42514:LOC108431661
uniprot id: A0A3B4EJT1
names: Subcellular Location Annotation
messages: Nucleus

42514:snx18a
gene id: 42514:snx18a
uniprot id: A0A3B4CTI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

42514:dbpb
gene id: 42514:dbpb
uniprot id: A0A3B4CK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

42514:grin2da
gene id: 42514:grin2da
uniprot id: A0A3B4DC67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:mgat1a
gene id: 42514:mgat1a
uniprot id: A0A3B4E5R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

42514:pin4
gene id: 42514:pin4
uniprot id: A0A3B4EJX5
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

42514:crabp1a
gene id: 42514:crabp1a
uniprot id: A0A3B4D7E1
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

42514:pyroxd1
gene id: 42514:pyroxd1
uniprot id: A0A3B4DDC3
uniprot id: A0A3B4ER44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

42514:tnfrsf1a
gene id: 42514:tnfrsf1a
uniprot id: A0A3B4CR87
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:psmd8
gene id: 42514:psmd8
uniprot id: A0A3B4D5Y9
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

42514:si:rp71-1d10.5
gene id: 42514:si:rp71-1d10.5
uniprot id: A0A3B4EHS3
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108435735
gene id: 42514:LOC108435735
uniprot id: A0A3B4E6P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

42514:ppme1
gene id: 42514:ppme1
uniprot id: A0A3B4CK58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

42514:cept1a
gene id: 42514:cept1a
uniprot id: A0A3B4CEU4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

42514:hnf4b
gene id: 42514:hnf4b
uniprot id: A0A3B4DZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:fgf20a
gene id: 42514:fgf20a
uniprot id: A0A3B4CPH3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:map6b
gene id: 42514:map6b
uniprot id: A0A3B4DTI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

42514:LOC108430196
gene id: 42514:LOC108430196
uniprot id: A0A3B4C2T8
names: Subcellular Location Annotation
messages: Membrane

42514:mark3a
gene id: 42514:mark3a
uniprot id: A0A3B4DCW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

42514:LOC108434698
gene id: 42514:LOC108434698
uniprot id: A0A3B4CMM7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

42514:foxm1
gene id: 42514:foxm1
uniprot id: A0A3B4EE59
names: Subcellular Location Annotation
messages: Nucleus

42514:jak1
gene id: 42514:jak1
uniprot id: A0A3B4BTN8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

42514:tmco1
gene id: 42514:tmco1
uniprot id: A0A3B4EB99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108440330
gene id: 42514:LOC108440330
uniprot id: A0A3B4BXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.

42514:thbs2a
gene id: 42514:thbs2a
uniprot id: A0A3B4DCS1
uniprot id: A0A3B4DE19
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:clic3
gene id: 42514:clic3
uniprot id: A0A3B4DHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

42514:LOC108413570
gene id: 42514:LOC108413570
uniprot id: A0A3B4E4F9
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

42514:fbln5
gene id: 42514:fbln5
uniprot id: A0A3B4C6Z5
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108414892
gene id: 42514:LOC108414892
uniprot id: A0A3B4C6B4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

42514:rspo3
gene id: 42514:rspo3
uniprot id: A0A3B4DS92
names: Similarity
messages: Belongs to the R-spondin family.

42514:unga
gene id: 42514:unga
uniprot id: A0A3B4E9F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

42514:dynll1
gene id: 42514:dynll1
uniprot id: A0A3B4DF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

42514:smdt1b
gene id: 42514:smdt1b
uniprot id: A0A3B4CE75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMDT1/EMRE family.
messages: Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.
messages: Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

42514:paqr4a
gene id: 42514:paqr4a
uniprot id: A0A3B4CR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:LOC108414109
gene id: 42514:LOC108414109
uniprot id: A0A3B4EK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:gmppb
gene id: 42514:gmppb
uniprot id: A0A3B4DFX2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

42514:gpr180
gene id: 42514:gpr180
uniprot id: A0A3B4BXK7
names: Subcellular Location Annotation
messages: Membrane

42514:g2e3
gene id: 42514:g2e3
uniprot id: A0A3B4CP64
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:mcl1b
gene id: 42514:mcl1b
uniprot id: A0A3B4C6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

42514:adra1ba
gene id: 42514:adra1ba
uniprot id: A0A3B4CAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

42514:LOC108442818
gene id: 42514:LOC108442818
uniprot id: A0A3B4D9M1
names: Similarity
messages: Belongs to the cornifelin family.

42514:LOC108437822
gene id: 42514:LOC108437822
uniprot id: A0A3B4CS44
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:lxn
gene id: 42514:lxn
uniprot id: A0A3B4BVM5
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

42514:ncstn
gene id: 42514:ncstn
uniprot id: A0A3B4ELG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

42514:tac3a
gene id: 42514:tac3a
uniprot id: A0A3B4D1I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

42514:tmco4
gene id: 42514:tmco4
uniprot id: A0A3B4CWQ2
names: Similarity
messages: Belongs to the TMCO4 family.

42514:pop5
gene id: 42514:pop5
uniprot id: A0A3B4C8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

42514:rp2
gene id: 42514:rp2
uniprot id: A0A3B4DV39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

42514:LOC108439881
gene id: 42514:LOC108439881
uniprot id: A0A3B4EK13
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:unc119.1
gene id: 42514:unc119.1
uniprot id: A0A3B4ELJ0
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

42514:c15h6orf120
gene id: 42514:c15h6orf120
uniprot id: A0A3B4C117
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

42514:aifm1
gene id: 42514:aifm1
uniprot id: A0A3B4BSS8
uniprot id: A0A3B4BSY2
uniprot id: A0A3B4DH67
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

42514:LOC108412147
gene id: 42514:LOC108412147
uniprot id: A0A3B4E8R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:elf2a
gene id: 42514:elf2a
uniprot id: A0A3B4DGW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:atg16l1
gene id: 42514:atg16l1
uniprot id: A0A3B4E0D8
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

42514:ttyh3a
gene id: 42514:ttyh3a
uniprot id: A0A3B4EBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

42514:lypla2
gene id: 42514:lypla2
uniprot id: A0A3B4EKI1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

42514:s100t
gene id: 42514:s100t
uniprot id: A0A3B4DRG1
names: Similarity
messages: Belongs to the S-100 family.

42514:vamp4
gene id: 42514:vamp4
uniprot id: A0A3B4DJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

42514:slc43a2b
gene id: 42514:slc43a2b
uniprot id: A0A3B4EI33
uniprot id: A0A3B4EJA5
names: Subcellular Location Annotation
messages: Membrane

42514:zcchc17
gene id: 42514:zcchc17
uniprot id: A0A3B4EJV8
names: Subcellular Location Annotation
messages: nucleolus

42514:trim36
gene id: 42514:trim36
uniprot id: A0A3B4C8G9
uniprot id: A0A3B4DV19
uniprot id: A0A3B4DXR1
names: Subcellular Location Annotation
messages: cytoskeleton

42514:si:dkey-69o16.5
gene id: 42514:si:dkey-69o16.5
uniprot id: A0A3B4C3B3
names: Similarity
messages: Belongs to the peptidase S51 family.

42514:ulk3
gene id: 42514:ulk3
uniprot id: A0A3B4CD78
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:tmem19
gene id: 42514:tmem19
uniprot id: A0A3B4EEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

42514:lyrm9
gene id: 42514:lyrm9
uniprot id: A0A3B4E2M6
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

42514:kif5bb
gene id: 42514:kif5bb
uniprot id: A0A3B4BTN1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:lhx1b
gene id: 42514:lhx1b
uniprot id: A0A3B4CBP6
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108414024
gene id: 42514:LOC108414024
uniprot id: A0A3B4DIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

42514:hadh
gene id: 42514:hadh
uniprot id: A0A3B4CPX1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

42514:kcng2
gene id: 42514:kcng2
uniprot id: A0A3B4D413
names: Subcellular Location Annotation
messages: Membrane

42514:ptx3b
gene id: 42514:ptx3b
uniprot id: A0A3B4DYT7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ino80
gene id: 42514:ino80
uniprot id: A0A3B4DQA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

42514:phb2a
gene id: 42514:phb2a
uniprot id: A0A3B4DPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

42514:mfsd14a1
gene id: 42514:mfsd14a1
uniprot id: A0A3B4BYK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

42514:LOC108428189
gene id: 42514:LOC108428189
uniprot id: A0A3B4EDG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:pus10
gene id: 42514:pus10
uniprot id: A0A3B4C9R8
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

42514:LOC108443717
gene id: 42514:LOC108443717
uniprot id: A0A3B4BUX1
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:faxca
gene id: 42514:faxca
uniprot id: A0A3B4EEU8
names: Similarity
messages: Belongs to the FAX family.

42514:celf4
gene id: 42514:celf4
uniprot id: A0A3B4D358
uniprot id: A0A3B4D6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

42514:ptk2bb
gene id: 42514:ptk2bb
uniprot id: A0A3B4EKX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

42514:LOC108431827
gene id: 42514:LOC108431827
uniprot id: A0A3B4CG93
uniprot id: A0A3B4CHU4
uniprot id: A0A3B4CHV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:pdf
gene id: 42514:pdf
uniprot id: A0A3B4CNW3
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

42514:mapk1
gene id: 42514:mapk1
uniprot id: A0A3B4E7N0
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

42514:ptch1
gene id: 42514:ptch1
uniprot id: A0A3B4C2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

42514:fubp3
gene id: 42514:fubp3
uniprot id: A0A3B4C9T6
uniprot id: A0A3B4CB75
names: Subcellular Location Annotation
messages: Nucleus

42514:zgc:110782
gene id: 42514:zgc:110782
uniprot id: A0A3B4C592
names: Similarity
messages: Belongs to the aldo/keto reductase family.

42514:riox1
gene id: 42514:riox1
uniprot id: A0A3B4DT88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

42514:elocb
gene id: 42514:elocb
uniprot id: A0A3B4E821
names: Similarity
messages: Belongs to the SKP1 family.

42514:mboat2a
gene id: 42514:mboat2a
uniprot id: A0A3B4CMK7
names: Subcellular Location Annotation
messages: Membrane

42514:slc16a9b
gene id: 42514:slc16a9b
uniprot id: A0A3B4CRP9
names: Subcellular Location Annotation
messages: Membrane

42514:ap4m1
gene id: 42514:ap4m1
uniprot id: A0A3B4DIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal.
messages: Early endosome
messages: trans-Golgi network membrane

42514:trmt1l
gene id: 42514:trmt1l
uniprot id: A0A3B4DDH3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

42514:ncdn
gene id: 42514:ncdn
uniprot id: A0A3B4EHI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurochondrin family.
messages: Postsynapse

42514:p3h1
gene id: 42514:p3h1
uniprot id: A0A3B4BY09
names: Similarity
messages: Belongs to the leprecan family.

42514:s1pr1
gene id: 42514:s1pr1
uniprot id: A0A3B4EEP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:LOC108430666
gene id: 42514:LOC108430666
uniprot id: A0A3B4CTR4
names: Similarity
messages: Belongs to the formin homology family. Cappuccino subfamily.

42514:LOC108443348
gene id: 42514:LOC108443348
uniprot id: A0A3B4EI01
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:cks2
gene id: 42514:cks2
uniprot id: A0A3B4BXN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

42514:zgc:162171
gene id: 42514:zgc:162171
uniprot id: A0A3B4CBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

42514:elp3
gene id: 42514:elp3
uniprot id: A0A3B4DEC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

42514:zgc:173742
gene id: 42514:zgc:173742
uniprot id: A0A3B4E8Q8
uniprot id: A0A3B4EA13
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

42514:cfap97
gene id: 42514:cfap97
uniprot id: A0A3B4CNS3
names: Similarity
messages: Belongs to the CFAP97 family.

42514:hspb6
gene id: 42514:hspb6
uniprot id: A0A3B4DXG7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:grk7a
gene id: 42514:grk7a
uniprot id: A0A3B4E6W8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

42514:acsl3a
gene id: 42514:acsl3a
uniprot id: A0A3B4CY67
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:ppp3ca
gene id: 42514:ppp3ca
uniprot id: A0A3B4C6Y7
uniprot id: A0A3B4C7K1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

42514:shfl
gene id: 42514:shfl
uniprot id: A0A3B4E2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Nucleus
messages: P-body

42514:glrba
gene id: 42514:glrba
uniprot id: A0A3B4D7X2
uniprot id: A0A3B4EL48
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:srp54
gene id: 42514:srp54
uniprot id: A0A3B4DKQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

42514:nr4a3
gene id: 42514:nr4a3
uniprot id: A0A3B4EIZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Cytoplasm
messages: Nucleus

42514:chmp6b
gene id: 42514:chmp6b
uniprot id: A0A3B4DU31
names: Similarity
messages: Belongs to the SNF7 family.

42514:gcsha
gene id: 42514:gcsha
uniprot id: A0A3B4D9T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

42514:pcolceb
gene id: 42514:pcolceb
uniprot id: A0A3B4BZG2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:ap1m2
gene id: 42514:ap1m2
uniprot id: A0A3B4DHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Golgi apparatus
messages: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
messages: clathrin-coated vesicle membrane

42514:mutyh
gene id: 42514:mutyh
uniprot id: A0A3B4E433
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

42514:ccser1
gene id: 42514:ccser1
uniprot id: A0A3B4C948
names: Similarity
messages: Belongs to the CCSER family.

42514:polr1b
gene id: 42514:polr1b
uniprot id: A0A3B4DU94
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.

42514:slc5a6a
gene id: 42514:slc5a6a
uniprot id: A0A3B4DAA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:ppp1r9ba
gene id: 42514:ppp1r9ba
uniprot id: A0A3B4E396
names: Subcellular Location Annotation
messages: cytoskeleton

42514:mffb
gene id: 42514:mffb
uniprot id: A0A3B4EL06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

42514:prokr1a
gene id: 42514:prokr1a
uniprot id: A0A3B4EAP6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:ubl3b
gene id: 42514:ubl3b
uniprot id: A0A3B4EAY5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:LOC108433121
gene id: 42514:LOC108433121
uniprot id: A0A3B4C0N1
uniprot id: A0A3B4DT73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

42514:LOC108435576
gene id: 42514:LOC108435576
uniprot id: A0A3B4EGZ3
names: Subcellular Location Annotation
messages: Membrane

42514:imp3
gene id: 42514:imp3
uniprot id: A0A3B4CLN8
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

42514:tspan33a
gene id: 42514:tspan33a
uniprot id: A0A3B4BTX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:zgc:112052
gene id: 42514:zgc:112052
uniprot id: A0A3B4ECT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

42514:hs3st1
gene id: 42514:hs3st1
uniprot id: A0A3B4C5Z8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:aspn
gene id: 42514:aspn
uniprot id: A0A3B4BRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

42514:vta1
gene id: 42514:vta1
uniprot id: A0A3B4DBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

42514:dscc1
gene id: 42514:dscc1
uniprot id: A0A3B4BKS3
names: Similarity
messages: Belongs to the DCC1 family.

42514:dlx5a
gene id: 42514:dlx5a
uniprot id: A0A3B4DG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

42514:efnb3b
gene id: 42514:efnb3b
uniprot id: A0A3B4DUQ1
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:atg4da
gene id: 42514:atg4da
uniprot id: A0A3B4E6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

42514:ppp6r3
gene id: 42514:ppp6r3
uniprot id: A0A3B4CAC2
uniprot id: A0A3B4DX98
names: Similarity
messages: Belongs to the SAPS family.

42514:psmd7
gene id: 42514:psmd7
uniprot id: A0A3B4DZ10
names: Similarity
messages: Belongs to the peptidase M67A family.

42514:grin3a
gene id: 42514:grin3a
uniprot id: A0A3B4E4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:erh
gene id: 42514:erh
uniprot id: A0A3B4CJD2
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

42514:orai2
gene id: 42514:orai2
uniprot id: A0A3B4CKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

42514:arsia
gene id: 42514:arsia
uniprot id: A0A3B4DBQ4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:cldn11a
gene id: 42514:cldn11a
uniprot id: A0A3B4E943
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:ror2
gene id: 42514:ror2
uniprot id: A0A3B4CRZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108413844
gene id: 42514:LOC108413844
uniprot id: A0A3B4EJM5
names: Similarity
messages: Belongs to the serpin family.

42514:LOC108437803
gene id: 42514:LOC108437803
uniprot id: A0A3B4ED81
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

42514:timm21
gene id: 42514:timm21
uniprot id: A0A3B4CZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

42514:g6pcb
gene id: 42514:g6pcb
uniprot id: A0A3B4CCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

42514:apc2
gene id: 42514:apc2
uniprot id: A0A3B4EFG9
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

42514:myo1ca
gene id: 42514:myo1ca
uniprot id: A0A3B4DSM0
uniprot id: A0A3B4DSR2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:abcb6a
gene id: 42514:abcb6a
uniprot id: A0A3B4BU67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

42514:gad1a
gene id: 42514:gad1a
uniprot id: A0A3B4E9Q3
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

42514:dnajc16l
gene id: 42514:dnajc16l
uniprot id: A0A3B4DTN1
names: Subcellular Location Annotation
messages: Membrane

42514:hprt1
gene id: 42514:hprt1
uniprot id: A0A3B4CU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

42514:zgc:109913
gene id: 42514:zgc:109913
uniprot id: A0A3B4D610
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

42514:rtcb
gene id: 42514:rtcb
uniprot id: A0A3B4DMD0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

42514:rpl38
gene id: 42514:rpl38
uniprot id: A0A3B4DH84
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

42514:wdr55
gene id: 42514:wdr55
uniprot id: A0A3B4CE29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: nucleolus

42514:tbpl1
gene id: 42514:tbpl1
uniprot id: A0A3B4EJG3
names: Similarity
messages: Belongs to the TBP family.

42514:prps1b
gene id: 42514:prps1b
uniprot id: A0A3B4DF22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

42514:LOC108430117
gene id: 42514:LOC108430117
uniprot id: A0A3B4CHK1
uniprot id: A0A3B4CHN1
uniprot id: A0A3B4E2X2
uniprot id: A0A3B4E468
uniprot id: A0A3B4E473
uniprot id: A0A3B4E482
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:pkp3b
gene id: 42514:pkp3b
uniprot id: A0A3B4CF84
names: Similarity
messages: Belongs to the beta-catenin family.

42514:LOC108427387
gene id: 42514:LOC108427387
uniprot id: A0A3B4CIL6
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:trpm3
gene id: 42514:trpm3
uniprot id: A0A3B4EFX6
names: Subcellular Location Annotation
messages: Membrane

42514:nutf2
gene id: 42514:nutf2
uniprot id: A0A3B4CL27
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

42514:LOC108411011
gene id: 42514:LOC108411011
uniprot id: A0A3B4D336
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

42514:glra2
gene id: 42514:glra2
uniprot id: A0A3B4BW53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

42514:nnt
gene id: 42514:nnt
uniprot id: A0A3B4BXZ2
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

42514:elovl2
gene id: 42514:elovl2
uniprot id: A0A3B4D2Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:si:dkey-148a17.6
gene id: 42514:si:dkey-148a17.6
uniprot id: A0A3B4DWX8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:LOC108424804
gene id: 42514:LOC108424804
uniprot id: A0A3B4DE72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tex10
gene id: 42514:tex10
uniprot id: A0A3B4D6P8
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

42514:dpysl4
gene id: 42514:dpysl4
uniprot id: A0A3B4C3B7
uniprot id: A0A3B4C663
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

42514:LOC108443953
gene id: 42514:LOC108443953
uniprot id: A0A3B4D8C2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:LOC108440166
gene id: 42514:LOC108440166
uniprot id: A0A3B4E561
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

42514:mtfp1
gene id: 42514:mtfp1
uniprot id: A0A3B4EK41
names: Similarity
messages: Belongs to the MTFP1 family.

42514:pbx3b
gene id: 42514:pbx3b
uniprot id: A0A3B4DAU6
uniprot id: A0A3B4EL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

42514:LOC108424660
gene id: 42514:LOC108424660
uniprot id: A0A3B4BRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

42514:rtn3
gene id: 42514:rtn3
uniprot id: A0A3B4C9F2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:plag1
gene id: 42514:plag1
uniprot id: A0A3B4CWU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

42514:blvra
gene id: 42514:blvra
uniprot id: A0A3B4D823
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.
messages: Monomer.
messages: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
messages: cytosol

42514:adgra2
gene id: 42514:adgra2
uniprot id: A0A3B4CM14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

42514:LOC108414170
gene id: 42514:LOC108414170
uniprot id: A0A3B4DI29
names: Subcellular Location Annotation
messages: Membrane

42514:fermt2
gene id: 42514:fermt2
uniprot id: A0A3B4BR26
uniprot id: A0A3B4BUI1
uniprot id: A0A3B4BUJ8
names: Similarity
messages: Belongs to the kindlin family.

42514:eml1
gene id: 42514:eml1
uniprot id: A0A3B4CKQ3
uniprot id: A0A3B4CMX4
uniprot id: A0A3B4E5X5
names: Similarity
messages: Belongs to the WD repeat EMAP family.

42514:serpinh2
gene id: 42514:serpinh2
uniprot id: A0A3B4D4J8
names: Similarity
messages: Belongs to the serpin family.

42514:grhpra
gene id: 42514:grhpra
uniprot id: A0A3B4CSW3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

42514:dock4b
gene id: 42514:dock4b
uniprot id: A0A3B4DCK2
uniprot id: A0A3B4DE57
names: Similarity
messages: Belongs to the DOCK family.

42514:elavl2
gene id: 42514:elavl2
uniprot id: A0A3B4DFZ6
names: Similarity
messages: Belongs to the RRM elav family.

42514:ano5b
gene id: 42514:ano5b
uniprot id: A0A3B4CDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

42514:zdhhc17
gene id: 42514:zdhhc17
uniprot id: A0A3B4BWK5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:LOC108440948
gene id: 42514:LOC108440948
uniprot id: A0A3B4BUG0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:pdxkb
gene id: 42514:pdxkb
uniprot id: A0A3B4D3P7
uniprot id: A0A3B4EJS3
names: Similarity
messages: Belongs to the pyridoxine kinase family.

42514:LOC108412406
gene id: 42514:LOC108412406
uniprot id: A0A3B4BZ96
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:drc1
gene id: 42514:drc1
uniprot id: A0A3B4CJN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

42514:ccn2b
gene id: 42514:ccn2b
uniprot id: A0A3B4EFD9
uniprot id: A0A3B4EGV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:cep19
gene id: 42514:cep19
uniprot id: A0A3B4EAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: centriole
messages: cilium basal body
messages: spindle pole

42514:LOC108433416
gene id: 42514:LOC108433416
uniprot id: A0A3B4CW24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

42514:hspa9
gene id: 42514:hspa9
uniprot id: A0A3B4ENN0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:kdm7ab
gene id: 42514:kdm7ab
uniprot id: A0A3B4DHQ9
names: Similarity
messages: Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.

42514:LOC108428606
gene id: 42514:LOC108428606
uniprot id: A0A3B4DNP4
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

42514:LOC108439233
gene id: 42514:LOC108439233
uniprot id: A0A3B4C1R5
names: Subcellular Location Annotation
messages: Membrane

42514:flvcr1
gene id: 42514:flvcr1
uniprot id: A0A3B4DEV0
names: Subcellular Location Annotation
messages: Membrane

42514:atp5mc1
gene id: 42514:atp5mc1
uniprot id: A0A3B4CHV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

42514:cadm2b
gene id: 42514:cadm2b
uniprot id: A0A3B4BVG1
uniprot id: A0A3B4BYM3
uniprot id: A0A3B4BYR9
names: Similarity
messages: Belongs to the nectin family.

42514:cnpy2
gene id: 42514:cnpy2
uniprot id: A0A3B4BRY7
names: Similarity
messages: Belongs to the canopy family.

42514:dhrs13b.1
gene id: 42514:dhrs13b.1
uniprot id: A0A3B4DPN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:nupr1b
gene id: 42514:nupr1b
uniprot id: A0A3B4CC45
names: Similarity
messages: Belongs to the NUPR family.

42514:peli3
gene id: 42514:peli3
uniprot id: A0A3B4DWX1
names: Similarity
messages: Belongs to the pellino family.

42514:bokb
gene id: 42514:bokb
uniprot id: A0A3B4BZW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

42514:ribc1
gene id: 42514:ribc1
uniprot id: A0A3B4D1G2
names: Similarity
messages: Belongs to the RIB43A family.

42514:kansl2
gene id: 42514:kansl2
uniprot id: A0A3B4CRF7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

42514:clta
gene id: 42514:clta
uniprot id: A0A3B4CVN8
uniprot id: A0A3B4CXB4
uniprot id: A0A3B4CY07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

42514:ydjc
gene id: 42514:ydjc
uniprot id: A0A3B4CVP0
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

42514:arxa
gene id: 42514:arxa
uniprot id: A0A3B4CYK0
names: Subcellular Location Annotation
messages: Nucleus

42514:si:ch211-153b23.4
gene id: 42514:si:ch211-153b23.4
uniprot id: A0A3B4CSF8
names: Similarity
messages: Belongs to the SUA5 family.

42514:g6pd
gene id: 42514:g6pd
uniprot id: A0A3B4CSW1
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

42514:lnpa
gene id: 42514:lnpa
uniprot id: A0A3B4CX90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

42514:klhl3
gene id: 42514:klhl3
uniprot id: A0A3B4D2N1
names: Subcellular Location Annotation
messages: cytoskeleton
messages: cytosol

42514:galntl6
gene id: 42514:galntl6
uniprot id: A0A3B4CPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:ipo4
gene id: 42514:ipo4
uniprot id: A0A3B4DBK1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:ncapd3
gene id: 42514:ncapd3
uniprot id: A0A3B4EL55
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the condensin-2 complex.
messages: Nucleus
messages: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

42514:cacng1a
gene id: 42514:cacng1a
uniprot id: A0A3B4DHS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

42514:amigo1
gene id: 42514:amigo1
uniprot id: A0A3B4DJ95
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

42514:abl2
gene id: 42514:abl2
uniprot id: A0A3B4CKH4
uniprot id: A0A3B4E5S8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:LOC108414326
gene id: 42514:LOC108414326
uniprot id: A0A3B4BKI8
names: Similarity
messages: Belongs to the MHC class I family.

42514:cyfip2
gene id: 42514:cyfip2
uniprot id: A0A3B4EA11
names: Similarity
messages: Belongs to the CYFIP family.

42514:pdlim1
gene id: 42514:pdlim1
uniprot id: A0A3B4CH56
names: Subcellular Location Annotation
messages: Z line

42514:pex7
gene id: 42514:pex7
uniprot id: A0A3B4DQF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

42514:lbx1b
gene id: 42514:lbx1b
uniprot id: A0A3B4BU28
names: Subcellular Location Annotation
messages: Nucleus

42514:dusp2
gene id: 42514:dusp2
uniprot id: A0A3B4CQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

42514:ptpn3
gene id: 42514:ptpn3
uniprot id: A0A3B4DF71
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.

42514:dnaja
gene id: 42514:dnaja
uniprot id: A0A3B4C6Z1
names: Subcellular Location Annotation
messages: Membrane

42514:clec14a
gene id: 42514:clec14a
uniprot id: A0A3B4DK91
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:scn1bb
gene id: 42514:scn1bb
uniprot id: A0A3B4C0C3
names: Subcellular Location Annotation
messages: Membrane

42514:xpot
gene id: 42514:xpot
uniprot id: A0A3B4DM72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

42514:furina
gene id: 42514:furina
uniprot id: A0A3B4DWB5
names: Similarity
messages: Belongs to the peptidase S8 family.

42514:vps52
gene id: 42514:vps52
uniprot id: A0A3B4DBL7
names: Similarity
messages: Belongs to the VPS52 family.

42514:LOC108438421
gene id: 42514:LOC108438421
uniprot id: A0A3B4EBH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:lin52
gene id: 42514:lin52
uniprot id: A0A3B4CZ62
names: Similarity
messages: Belongs to the lin-52 family.

42514:lim2.1
gene id: 42514:lim2.1
uniprot id: A0A3B4E7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

42514:kcnf1b
gene id: 42514:kcnf1b
uniprot id: A0A3B4DTG3
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108416022
gene id: 42514:LOC108416022
uniprot id: A0A3B4EA73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:si:dkey-42i9.4
gene id: 42514:si:dkey-42i9.4
uniprot id: A0A3B4BRU1
names: Similarity
messages: Belongs to the BTG family.

42514:cd164
gene id: 42514:cd164
uniprot id: A0A3B4BWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

42514:zgc:86598
gene id: 42514:zgc:86598
uniprot id: A0A3B4BSW3
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:fam172a
gene id: 42514:fam172a
uniprot id: A0A3B4EHV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM172 family.
messages: Cytoplasm
messages: Nucleus

42514:ncaph2
gene id: 42514:ncaph2
uniprot id: A0A3B4DMX5
names: Similarity
messages: Belongs to the CND2 H2 (condensin-2 subunit 2) family.

42514:ctnna1
gene id: 42514:ctnna1
uniprot id: A0A3B4CNC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

42514:anapc11
gene id: 42514:anapc11
uniprot id: A0A3B4DBM6
names: Similarity
messages: Belongs to the RING-box family.

42514:sap130b
gene id: 42514:sap130b
uniprot id: A0A3B4BYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

42514:eya2
gene id: 42514:eya2
uniprot id: A0A3B4E1J6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

42514:slc5a5
gene id: 42514:slc5a5
uniprot id: A0A3B4D5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:vangl1
gene id: 42514:vangl1
uniprot id: A0A3B4BNI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

42514:sugct
gene id: 42514:sugct
uniprot id: A0A3B4DJ47
names: Similarity
messages: Belongs to the CoA-transferase III family.

42514:tctn1
gene id: 42514:tctn1
uniprot id: A0A3B4BVI0
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

42514:atp6ap1b
gene id: 42514:atp6ap1b
uniprot id: A0A3B4CPB4
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

42514:gata2a
gene id: 42514:gata2a
uniprot id: A0A3B4CAH1
names: Subcellular Location Annotation
messages: Nucleus

42514:echs1
gene id: 42514:echs1
uniprot id: A0A3B4CAR2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

42514:mat2aa
gene id: 42514:mat2aa
uniprot id: A0A3B4DNV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

42514:LOC108428858
gene id: 42514:LOC108428858
uniprot id: A0A3B4D7P1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

42514:usp2b
gene id: 42514:usp2b
uniprot id: A0A3B4DF92
uniprot id: A0A3B4DFA2
names: Similarity
messages: Belongs to the peptidase C19 family.

42514:ccr10
gene id: 42514:ccr10
uniprot id: A0A3B4CAJ7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:casp9
gene id: 42514:casp9
uniprot id: A0A3B4E9S7
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:cope
gene id: 42514:cope
uniprot id: A0A3B4E7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

42514:ext1a
gene id: 42514:ext1a
uniprot id: A0A3B4C3K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

42514:pdcd10b
gene id: 42514:pdcd10b
uniprot id: A0A3B4CCM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

42514:pgm3
gene id: 42514:pgm3
uniprot id: A0A3B4D1X9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

42514:LOC108430602
gene id: 42514:LOC108430602
uniprot id: A0A3B4CZ74
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:LOC108431583
gene id: 42514:LOC108431583
uniprot id: A0A3B4DE78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:daxx
gene id: 42514:daxx
uniprot id: A0A3B4DRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

42514:LOC108438916
gene id: 42514:LOC108438916
uniprot id: A0A3B4D0P3
names: Subcellular Location Annotation
messages: Membrane

42514:ppp4r2b
gene id: 42514:ppp4r2b
uniprot id: A0A3B4CGQ1
names: Similarity
messages: Belongs to the PPP4R2 family.

42514:bms1
gene id: 42514:bms1
uniprot id: A0A3B4BP42
names: Subcellular Location Annotation
messages: nucleolus

42514:bloc1s1
gene id: 42514:bloc1s1
uniprot id: A0A3B4DHA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Mitochondrion intermembrane space

42514:nfia
gene id: 42514:nfia
uniprot id: A0A3B4CVH3
uniprot id: A0A3B4CVI6
uniprot id: A0A3B4CXQ2
uniprot id: A0A3B4E8W4
uniprot id: A0A3B4EB22
uniprot id: A0A3B4ECI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

42514:cenpj
gene id: 42514:cenpj
uniprot id: A0A3B4EMU9
names: Similarity
messages: Belongs to the TCP10 family.

42514:hspb7
gene id: 42514:hspb7
uniprot id: A0A3B4CTJ2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

42514:cert1b
gene id: 42514:cert1b
uniprot id: A0A3B4BV38
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

42514:zgc:165653
gene id: 42514:zgc:165653
uniprot id: A0A3B4CP20
names: Similarity
messages: Belongs to the alpha-actinin family.

42514:scn5lab
gene id: 42514:scn5lab
uniprot id: A0A3B4EKV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

42514:p2rx1
gene id: 42514:p2rx1
uniprot id: A0A3B4DTY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

42514:pdk4
gene id: 42514:pdk4
uniprot id: A0A3B4DEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

42514:zmp:0000000926
gene id: 42514:zmp:0000000926
uniprot id: A0A3B4C1N1
names: Subcellular Location Annotation
messages: Nucleus

42514:creb3l4
gene id: 42514:creb3l4
uniprot id: A0A3B4CW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:ppp1cc
gene id: 42514:ppp1cc
uniprot id: A0A3B4EKK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody

42514:pde6c
gene id: 42514:pde6c
uniprot id: A0A3B4C7Y8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:pcna
gene id: 42514:pcna
uniprot id: A0A3B4CN66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

42514:psmc4
gene id: 42514:psmc4
uniprot id: A0A3B4CXE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

42514:stx16
gene id: 42514:stx16
uniprot id: A0A3B4DUT8
names: Similarity
messages: Belongs to the syntaxin family.

42514:ro60
gene id: 42514:ro60
uniprot id: A0A3B4D317
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

42514:tp53i11a
gene id: 42514:tp53i11a
uniprot id: A0A3B4CEK2
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108410462
gene id: 42514:LOC108410462
uniprot id: A0A3B4D259
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:gchfr
gene id: 42514:gchfr
uniprot id: A0A3B4EB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

42514:zgc:154075
gene id: 42514:zgc:154075
uniprot id: A0A3B4CNU8
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

42514:dnase1l1
gene id: 42514:dnase1l1
uniprot id: A0A3B4DZ16
names: Similarity
messages: Belongs to the DNase I family.

42514:alg3
gene id: 42514:alg3
uniprot id: A0A3B4EBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Belongs to the glycosyltransferase 58 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:dynll2b
gene id: 42514:dynll2b
uniprot id: A0A3B4E0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

42514:rpl9
gene id: 42514:rpl9
uniprot id: A0A3B4DAC9
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

42514:stoml3a
gene id: 42514:stoml3a
uniprot id: A0A3B4BZC3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

42514:gna13b
gene id: 42514:gna13b
uniprot id: A0A3B4C8K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

42514:ctsbb
gene id: 42514:ctsbb
uniprot id: A0A3B4DIW6
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:gas6
gene id: 42514:gas6
uniprot id: A0A3B4DQJ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:galcb
gene id: 42514:galcb
uniprot id: A0A3B4EGT0
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

42514:fam149a
gene id: 42514:fam149a
uniprot id: A0A3B4D371
names: Similarity
messages: Belongs to the FAM149 family.

42514:igflr1
gene id: 42514:igflr1
uniprot id: A0A3B4C9S1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:b4galnt4b
gene id: 42514:b4galnt4b
uniprot id: A0A3B4E5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

42514:ube2b
gene id: 42514:ube2b
uniprot id: A0A3B4CFE5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:LOC108412425
gene id: 42514:LOC108412425
uniprot id: A0A3B4C2N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: Membrane raft

42514:si:busm1-52i16.2
gene id: 42514:si:busm1-52i16.2
uniprot id: A0A3B4C0U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:xpo1a
gene id: 42514:xpo1a
uniprot id: A0A3B4C9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

42514:adcyap1a
gene id: 42514:adcyap1a
uniprot id: A0A3B4EBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

42514:slc35d1b
gene id: 42514:slc35d1b
uniprot id: A0A3B4D4W3
names: Subcellular Location Annotation
messages: Membrane

42514:ell2
gene id: 42514:ell2
uniprot id: A0A3B4D4Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

42514:dhx58
gene id: 42514:dhx58
uniprot id: A0A3B4EMP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

42514:ppp1r1b
gene id: 42514:ppp1r1b
uniprot id: A0A3B4BPI2
uniprot id: A0A3B4BSI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein phosphatase inhibitor 1 family.
messages: Cytoplasm
messages: Inhibitor of protein-phosphatase 1.

42514:naa40
gene id: 42514:naa40
uniprot id: A0A3B4CN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

42514:LOC108423490
gene id: 42514:LOC108423490
uniprot id: A0A3B4BZW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: extracellular exosome

42514:pth3r
gene id: 42514:pth3r
uniprot id: A0A3B4BTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

42514:twf1b
gene id: 42514:twf1b
uniprot id: A0A3B4CZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

42514:bcl2l16
gene id: 42514:bcl2l16
uniprot id: A0A3B4CYY0
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:LOC108435793
gene id: 42514:LOC108435793
uniprot id: A0A3B4CFZ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tbx15
gene id: 42514:tbx15
uniprot id: A0A3B4C234
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:nrf1
gene id: 42514:nrf1
uniprot id: A0A3B4CRN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

42514:hs6st1b
gene id: 42514:hs6st1b
uniprot id: A0A3B4DGJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

42514:tlr7
gene id: 42514:tlr7
uniprot id: A0A3B4DQW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

42514:lim2.2
gene id: 42514:lim2.2
uniprot id: A0A3B4EEQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

42514:ptgesl
gene id: 42514:ptgesl
uniprot id: A0A3B4C1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

42514:ccdc149a
gene id: 42514:ccdc149a
uniprot id: A0A3B4BYW9
uniprot id: A0A3B4DP48
names: Similarity
messages: Belongs to the CCDC149 family.

42514:csf1ra
gene id: 42514:csf1ra
uniprot id: A0A3B4DQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:spty2d1
gene id: 42514:spty2d1
uniprot id: A0A3B4BXC0
names: Similarity
messages: Belongs to the SPT2 family.

42514:spsb4b
gene id: 42514:spsb4b
uniprot id: A0A3B4DAP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

42514:LOC108424788
gene id: 42514:LOC108424788
uniprot id: A0A3B4ELI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

42514:fundc2
gene id: 42514:fundc2
uniprot id: A0A3B4D605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

42514:slco2a1
gene id: 42514:slco2a1
uniprot id: A0A3B4EMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

42514:araf
gene id: 42514:araf
uniprot id: A0A3B4BW13
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

42514:LOC108441374
gene id: 42514:LOC108441374
uniprot id: A0A3B4DZS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:cacng8a
gene id: 42514:cacng8a
uniprot id: A0A3B4DB44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

42514:necap2
gene id: 42514:necap2
uniprot id: A0A3B4BP24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

42514:rffl
gene id: 42514:rffl
uniprot id: A0A3B4C359
names: Subcellular Location Annotation
messages: Cell membrane

42514:myo10l1
gene id: 42514:myo10l1
uniprot id: A0A3B4CA17
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:btf3
gene id: 42514:btf3
uniprot id: A0A3B4CX00
names: Similarity
messages: Belongs to the NAC-beta family.

42514:utp3
gene id: 42514:utp3
uniprot id: A0A3B4BP97
names: Similarity
messages: Belongs to the SAS10 family.

42514:mrps11
gene id: 42514:mrps11
uniprot id: A0A3B4DY25
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

42514:irgq2
gene id: 42514:irgq2
uniprot id: A0A3B4BUL2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

42514:cfap126
gene id: 42514:cfap126
uniprot id: A0A3B4CEF4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

42514:LOC108411899
gene id: 42514:LOC108411899
uniprot id: A0A3B4C6T9
names: Similarity
messages: Belongs to the SEC6 family.

42514:vax1
gene id: 42514:vax1
uniprot id: A0A3B4D5A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

42514:scrn2
gene id: 42514:scrn2
uniprot id: A0A3B4ER41
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

42514:dusp4
gene id: 42514:dusp4
uniprot id: A0A3B4BVF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

42514:plppr1
gene id: 42514:plppr1
uniprot id: A0A3B4E342
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

42514:foxd1
gene id: 42514:foxd1
uniprot id: A0A3B4ECJ2
names: Subcellular Location Annotation
messages: Nucleus

42514:cry3a
gene id: 42514:cry3a
uniprot id: A0A3B4EEE4
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

42514:cpsf4
gene id: 42514:cpsf4
uniprot id: A0A3B4EF74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

42514:ywhag1
gene id: 42514:ywhag1
uniprot id: A0A3B4DMY0
names: Similarity
names: Subunit
messages: Belongs to the 14-3-3 family.
messages: Homodimer, and heterodimer with other family members.

42514:mxe
gene id: 42514:mxe
uniprot id: A0A3B4CEH9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

42514:fbln2
gene id: 42514:fbln2
uniprot id: A0A3B4BNW1
uniprot id: A0A3B4BPB6
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:serpinh1a
gene id: 42514:serpinh1a
uniprot id: A0A3B4CDX7
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

42514:lmod1b
gene id: 42514:lmod1b
uniprot id: A0A3B4CD84
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

42514:slc7a1b
gene id: 42514:slc7a1b
uniprot id: A0A3B4BZ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:otx2a
gene id: 42514:otx2a
uniprot id: A0A3B4DZ22
names: Subcellular Location Annotation
messages: Nucleus

42514:cdt1
gene id: 42514:cdt1
uniprot id: A0A3B4CVX1
names: Similarity
messages: Belongs to the Cdt1 family.

42514:LOC108429393
gene id: 42514:LOC108429393
uniprot id: A0A3B4EJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:rab3da
gene id: 42514:rab3da
uniprot id: A0A3B4C0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

42514:LOC108427201
gene id: 42514:LOC108427201
uniprot id: A0A3B4EEK8
names: Subcellular Location Annotation
messages: Nucleus

42514:fut10
gene id: 42514:fut10
uniprot id: A0A3B4ED14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

42514:LOC108411508
gene id: 42514:LOC108411508
uniprot id: A0A3B4EF05
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

42514:eif2ak3
gene id: 42514:eif2ak3
uniprot id: A0A3B4CI01
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

42514:pkn1a
gene id: 42514:pkn1a
uniprot id: A0A3B4D0N3
uniprot id: A0A3B4D2M6
uniprot id: A0A3B4D2N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

42514:kars1
gene id: 42514:kars1
uniprot id: A0A3B4DYQ2
uniprot id: A0A3B4DYV2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

42514:pigu
gene id: 42514:pigu
uniprot id: A0A3B4DS19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:tm9sf3
gene id: 42514:tm9sf3
uniprot id: A0A3B4DSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

42514:pax8
gene id: 42514:pax8
uniprot id: A0A3B4D7H8
uniprot id: A0A3B4EKQ9
names: Subcellular Location Annotation
messages: Nucleus

42514:grhprb
gene id: 42514:grhprb
uniprot id: A0A3B4DP08
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

42514:LOC108436163
gene id: 42514:LOC108436163
uniprot id: A0A3B4E677
names: Similarity
messages: Belongs to the SLBP family.

42514:si:ch211-195b15.7
gene id: 42514:si:ch211-195b15.7
uniprot id: A0A3B4E7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

42514:myo1ea
gene id: 42514:myo1ea
uniprot id: A0A3B4CQR0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

42514:ifrd2
gene id: 42514:ifrd2
uniprot id: A0A3B4CJH6
uniprot id: A0A3B4E6F1
names: Similarity
messages: Belongs to the IFRD family.

42514:tmem237b
gene id: 42514:tmem237b
uniprot id: A0A3B4CWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

42514:crygn2
gene id: 42514:crygn2
uniprot id: A0A3B4EJS5
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:rrad
gene id: 42514:rrad
uniprot id: A0A3B4DK75
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

42514:gpc2
gene id: 42514:gpc2
uniprot id: A0A3B4C5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

42514:acad8
gene id: 42514:acad8
uniprot id: A0A3B4C735
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

42514:acadm
gene id: 42514:acadm
uniprot id: A0A3B4DPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Mitochondrion matrix

42514:abcc6a
gene id: 42514:abcc6a
uniprot id: A0A3B4C5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

42514:si:dkey-13n15.2
gene id: 42514:si:dkey-13n15.2
uniprot id: A0A3B4BYP7
names: Subcellular Location Annotation
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:hacd4
gene id: 42514:hacd4
uniprot id: A0A3B4CQ40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:pdgfbb
gene id: 42514:pdgfbb
uniprot id: A0A3B4CC57
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

42514:txndc5
gene id: 42514:txndc5
uniprot id: A0A3B4D6E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

42514:baiap2a
gene id: 42514:baiap2a
uniprot id: A0A3B4D1F2
uniprot id: A0A3B4EDX0
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

42514:atp6v1c1b
gene id: 42514:atp6v1c1b
uniprot id: A0A3B4C4C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

42514:aff4
gene id: 42514:aff4
uniprot id: A0A3B4EJG9
uniprot id: A0A3B4EKZ2
names: Similarity
messages: Belongs to the AF4 family.

42514:aoc1
gene id: 42514:aoc1
uniprot id: A0A3B4CZM7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

42514:emc2
gene id: 42514:emc2
uniprot id: A0A3B4DR83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

42514:foxd5
gene id: 42514:foxd5
uniprot id: A0A3B4CBU6
names: Subcellular Location Annotation
messages: Nucleus

42514:si:ch73-383l1.1
gene id: 42514:si:ch73-383l1.1
uniprot id: A0A3B4EKH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

42514:LOC108428614
gene id: 42514:LOC108428614
uniprot id: A0A3B4DK87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

42514:LOC108441742
gene id: 42514:LOC108441742
uniprot id: A0A3B4E757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

42514:nucb1
gene id: 42514:nucb1
uniprot id: A0A3B4EPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobindin family.
messages: Cytoplasm
messages: Secreted
messages: cis-Golgi network membrane

42514:LOC108427382
gene id: 42514:LOC108427382
uniprot id: A0A3B4E619
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

42514:LOC108426311
gene id: 42514:LOC108426311
uniprot id: A0A3B4C274
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

42514:mef2d
gene id: 42514:mef2d
uniprot id: A0A3B4DUZ7
names: Subcellular Location Annotation
messages: Nucleus

42514:asic1b
gene id: 42514:asic1b
uniprot id: A0A3B4DJK1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:tdrd5
gene id: 42514:tdrd5
uniprot id: A0A3B4EBW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDRD5 family.
messages: Cytoplasm

42514:si:dkey-103j14.5
gene id: 42514:si:dkey-103j14.5
uniprot id: A0A3B4DMF5
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

42514:polr2d
gene id: 42514:polr2d
uniprot id: A0A3B4CPM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

42514:rtn4b
gene id: 42514:rtn4b
uniprot id: A0A3B4CA59
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:si:dkey-30c15.17
gene id: 42514:si:dkey-30c15.17
uniprot id: A0A3B4EIS7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

42514:hgd
gene id: 42514:hgd
uniprot id: A0A3B4D0H1
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

42514:hibadhb
gene id: 42514:hibadhb
uniprot id: A0A3B4BW05
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

42514:galnt6
gene id: 42514:galnt6
uniprot id: A0A3B4C726
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:oxr1a
gene id: 42514:oxr1a
uniprot id: A0A3B4E0B6
uniprot id: A0A3B4E1E5
names: Similarity
messages: Belongs to the OXR1 family.

42514:ndc1
gene id: 42514:ndc1
uniprot id: A0A3B4C2H7
uniprot id: A0A3B4C3M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

42514:LOC108428158
gene id: 42514:LOC108428158
uniprot id: A0A3B4DQ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Homodimer.

42514:sult5a1
gene id: 42514:sult5a1
uniprot id: A0A3B4C3D3
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:cdk5
gene id: 42514:cdk5
uniprot id: A0A3B4DWQ1
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:pnn
gene id: 42514:pnn
uniprot id: A0A3B4E5Q4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

42514:phlda1
gene id: 42514:phlda1
uniprot id: A0A3B4CXN0
names: Subcellular Location Annotation
messages: Cytoplasm

42514:yipf6
gene id: 42514:yipf6
uniprot id: A0A3B4BQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

42514:LOC108438160
gene id: 42514:LOC108438160
uniprot id: A0A3B4BQ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

42514:LOC108423643
gene id: 42514:LOC108423643
uniprot id: A0A3B4ENN2
names: Similarity
messages: Belongs to the peptidase M1 family.

42514:ubxn1
gene id: 42514:ubxn1
uniprot id: A0A3B4EEC9
names: Subcellular Location Annotation
messages: Cytoplasm

42514:dpysl5a
gene id: 42514:dpysl5a
uniprot id: A0A3B4CHY8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

42514:rpl21
gene id: 42514:rpl21
uniprot id: A0A3B4D5C6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

42514:ntrk2b
gene id: 42514:ntrk2b
uniprot id: A0A3B4BPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:pigv
gene id: 42514:pigv
uniprot id: A0A3B4EL41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

42514:LOC108435719
gene id: 42514:LOC108435719
uniprot id: A0A3B4E873
names: Subcellular Location Annotation
messages: Membrane
messages: Perikaryon

42514:tmem151bb
gene id: 42514:tmem151bb
uniprot id: A0A3B4DJN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

42514:dkk3a
gene id: 42514:dkk3a
uniprot id: A0A3B4E0E5
names: Similarity
messages: Belongs to the dickkopf family.

42514:eaf2
gene id: 42514:eaf2
uniprot id: A0A3B4BV21
names: Similarity
messages: Belongs to the EAF family.

42514:rab9b
gene id: 42514:rab9b
uniprot id: A0A3B4E5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: phagosome membrane

42514:LOC108427628
gene id: 42514:LOC108427628
uniprot id: A0A3B4DG28
names: Subcellular Location Annotation
messages: Nucleus

42514:slc25a29
gene id: 42514:slc25a29
uniprot id: A0A3B4CVN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:eif2d
gene id: 42514:eif2d
uniprot id: A0A3B4BP43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF2D family.
messages: Cytoplasm
messages: Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.

42514:LOC108429994
gene id: 42514:LOC108429994
uniprot id: A0A3B4EEI1
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:ggh
gene id: 42514:ggh
uniprot id: A0A3B4EBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C26 family.
messages: extracellular space

42514:mtrf1
gene id: 42514:mtrf1
uniprot id: A0A3B4BX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

42514:cant1b
gene id: 42514:cant1b
uniprot id: A0A3B4EFJ7
names: Similarity
messages: Belongs to the apyrase family.

42514:slc1a7b
gene id: 42514:slc1a7b
uniprot id: A0A3B4EDA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:LOC108444057
gene id: 42514:LOC108444057
uniprot id: A0A3B4EG13
names: Similarity
messages: Belongs to the methyltransferase superfamily.

42514:hoxb5a
gene id: 42514:hoxb5a
uniprot id: A0A3B4E136
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

42514:mms19
gene id: 42514:mms19
uniprot id: A0A3B4C7V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

42514:olfml2ba
gene id: 42514:olfml2ba
uniprot id: A0A3B4BP81
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108434837
gene id: 42514:LOC108434837
uniprot id: A0A3B4DWB1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

42514:qars1
gene id: 42514:qars1
uniprot id: A0A3B4DGN9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:slc17a9a
gene id: 42514:slc17a9a
uniprot id: A0A3B4BR68
names: Subcellular Location Annotation
messages: Membrane

42514:tbx2a
gene id: 42514:tbx2a
uniprot id: A0A3B4DZH9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:LOC108430712
gene id: 42514:LOC108430712
uniprot id: A0A3B4DYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108439593
gene id: 42514:LOC108439593
uniprot id: A0A3B4CL77
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108413752
gene id: 42514:LOC108413752
uniprot id: A0A3B4DQF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

42514:actb2
gene id: 42514:actb2
uniprot id: A0A3B4CWN6
names: Similarity
messages: Belongs to the actin family.

42514:slc39a9
gene id: 42514:slc39a9
uniprot id: A0A3B4BZG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

42514:gsk3aa
gene id: 42514:gsk3aa
uniprot id: A0A3B4BYG5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

42514:esrrd
gene id: 42514:esrrd
uniprot id: A0A3B4CRM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

42514:cdca8
gene id: 42514:cdca8
uniprot id: A0A3B4EFN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: centromere

42514:tyw3
gene id: 42514:tyw3
uniprot id: A0A3B4DD57
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

42514:rpl19
gene id: 42514:rpl19
uniprot id: A0A3B4C6L3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

42514:samm50l
gene id: 42514:samm50l
uniprot id: A0A3B4C0R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

42514:LOC108438794
gene id: 42514:LOC108438794
uniprot id: A0A3B4DDZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.

42514:LOC108429232
gene id: 42514:LOC108429232
uniprot id: A0A3B4DTG6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:si:dkey-97m3.1
gene id: 42514:si:dkey-97m3.1
uniprot id: A0A3B4D2D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

42514:tram1
gene id: 42514:tram1
uniprot id: A0A3B4EEE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

42514:sv2ba
gene id: 42514:sv2ba
uniprot id: A0A3B4C7L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

42514:cpne7
gene id: 42514:cpne7
uniprot id: A0A3B4CAU9
names: Similarity
messages: Belongs to the copine family.

42514:hmx3a
gene id: 42514:hmx3a
uniprot id: A0A3B4D524
names: Subcellular Location Annotation
messages: Nucleus

42514:tspan9b
gene id: 42514:tspan9b
uniprot id: A0A3B4BYB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:adgb
gene id: 42514:adgb
uniprot id: A0A3B4BWE2
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:gpr61l
gene id: 42514:gpr61l
uniprot id: A0A3B4E206
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:ncbp2
gene id: 42514:ncbp2
uniprot id: A0A3B4CX01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

42514:gabrr2b
gene id: 42514:gabrr2b
uniprot id: A0A3B4C708
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:prdm8b
gene id: 42514:prdm8b
uniprot id: A0A3B4E837
names: Subcellular Location Annotation
messages: Nucleus

42514:grinaa
gene id: 42514:grinaa
uniprot id: A0A3B4D4I2
names: Subcellular Location Annotation
messages: Membrane

42514:gdf10b
gene id: 42514:gdf10b
uniprot id: A0A3B4D2D7
names: Similarity
messages: Belongs to the TGF-beta family.

42514:npy2r
gene id: 42514:npy2r
uniprot id: A0A3B4BT93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:hal
gene id: 42514:hal
uniprot id: A0A3B4DHV2
names: Similarity
messages: Belongs to the PAL/histidase family.

42514:npr1b
gene id: 42514:npr1b
uniprot id: A0A3B4ENF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

42514:morf4l1
gene id: 42514:morf4l1
uniprot id: A0A3B4CAN8
names: Subcellular Location Annotation
messages: Nucleus

42514:zranb2
gene id: 42514:zranb2
uniprot id: A0A3B4C4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

42514:eif4ebp3
gene id: 42514:eif4ebp3
uniprot id: A0A3B4BZN4
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

42514:slc26a1
gene id: 42514:slc26a1
uniprot id: A0A3B4DP23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate.
messages: Membrane

42514:abhd2b
gene id: 42514:abhd2b
uniprot id: A0A3B4EDZ5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

42514:eif4ebp2
gene id: 42514:eif4ebp2
uniprot id: A0A3B4DG93
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

42514:pkp1b
gene id: 42514:pkp1b
uniprot id: A0A3B4BRT3
names: Similarity
messages: Belongs to the beta-catenin family.

42514:slc2a11a
gene id: 42514:slc2a11a
uniprot id: A0A3B4E419
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:snrpd3l
gene id: 42514:snrpd3l
uniprot id: A0A3B4DL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

42514:gdi1
gene id: 42514:gdi1
uniprot id: A0A3B4CR10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

42514:LOC108414658
gene id: 42514:LOC108414658
uniprot id: A0A3B4E685
names: Similarity
messages: Belongs to the peptidase A1 family.

42514:vgll4l
gene id: 42514:vgll4l
uniprot id: A0A3B4C1T3
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

42514:atp6v1d
gene id: 42514:atp6v1d
uniprot id: A0A3B4C482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

42514:gmfg
gene id: 42514:gmfg
uniprot id: A0A3B4CDX1
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

42514:LOC108412848
gene id: 42514:LOC108412848
uniprot id: A0A3B4CPS8
names: Similarity
messages: Belongs to the cystatin family.

42514:ilf3b
gene id: 42514:ilf3b
uniprot id: A0A3B4BPF0
uniprot id: A0A3B4BPX7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:b3gnt7l
gene id: 42514:b3gnt7l
uniprot id: A0A3B4E6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:arid1b
gene id: 42514:arid1b
uniprot id: A0A3B4EGE7
names: Subcellular Location Annotation
messages: Nucleus

42514:pisd
gene id: 42514:pisd
uniprot id: A0A3B4BLY5
uniprot id: A0A3B4BLZ1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

42514:LOC108410846
gene id: 42514:LOC108410846
uniprot id: A0A3B4DNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

42514:sesn2
gene id: 42514:sesn2
uniprot id: A0A3B4ELD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

42514:arid5b
gene id: 42514:arid5b
uniprot id: A0A3B4CN43
names: Similarity
messages: Belongs to the ARID5B family.

42514:prpf3
gene id: 42514:prpf3
uniprot id: A0A3B4C2K7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

42514:tmem161b
gene id: 42514:tmem161b
uniprot id: A0A3B4D5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

42514:si:ch73-21k16.1
gene id: 42514:si:ch73-21k16.1
uniprot id: A0A3B4DVH8
uniprot id: A0A3B4DVT1
names: Similarity
messages: Belongs to the lipin family.

42514:cops3
gene id: 42514:cops3
uniprot id: A0A3B4CUZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

42514:jak2a
gene id: 42514:jak2a
uniprot id: A0A3B4CLJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

42514:hmbox1a
gene id: 42514:hmbox1a
uniprot id: A0A3B4D6X5
uniprot id: A0A3B4D7Z6
names: Subcellular Location Annotation
messages: Nucleus

42514:kat8
gene id: 42514:kat8
uniprot id: A0A3B4E4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

42514:b9d1
gene id: 42514:b9d1
uniprot id: A0A3B4D153
names: Subcellular Location Annotation
messages: cilium basal body

42514:ndufb3
gene id: 42514:ndufb3
uniprot id: A0A3B4BM04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

42514:LOC108434675
gene id: 42514:LOC108434675
uniprot id: A0A3B4E3A1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:ddb2
gene id: 42514:ddb2
uniprot id: A0A3B4CAT8
uniprot id: A0A3B4CAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

42514:si:dkey-193b15.8
gene id: 42514:si:dkey-193b15.8
uniprot id: A0A3B4C7E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

42514:adkb
gene id: 42514:adkb
uniprot id: A0A3B4DHG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

42514:efemp2a
gene id: 42514:efemp2a
uniprot id: A0A3B4CT77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:slc15a1b
gene id: 42514:slc15a1b
uniprot id: A0A3B4CJ51
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

42514:gprc5c
gene id: 42514:gprc5c
uniprot id: A0A3B4C1R4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:immt
gene id: 42514:immt
uniprot id: A0A3B4CM44
uniprot id: A0A3B4E6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

42514:anapc13
gene id: 42514:anapc13
uniprot id: A0A3B4CJ01
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

42514:vgll3
gene id: 42514:vgll3
uniprot id: A0A3B4E403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

42514:LOC108442081
gene id: 42514:LOC108442081
uniprot id: A0A3B4BLY2
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

42514:rxrga
gene id: 42514:rxrga
uniprot id: A0A3B4E7V5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

42514:hs3st3l
gene id: 42514:hs3st3l
uniprot id: A0A3B4D6B2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:xcr1b.2
gene id: 42514:xcr1b.2
uniprot id: A0A3B4C4S4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:arhgef7b
gene id: 42514:arhgef7b
uniprot id: A0A3B4D3Z1
uniprot id: A0A3B4EH92
names: Subcellular Location Annotation
messages: lamellipodium

42514:zgc:113054
gene id: 42514:zgc:113054
uniprot id: A0A3B4DJ74
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

42514:smad6a
gene id: 42514:smad6a
uniprot id: A0A3B4CEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:si:dkeyp-67a8.2
gene id: 42514:si:dkeyp-67a8.2
uniprot id: A0A3B4CPZ8
names: Subcellular Location Annotation
messages: Membrane

42514:spg7
gene id: 42514:spg7
uniprot id: A0A3B4C7V0
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

42514:kpna5
gene id: 42514:kpna5
uniprot id: A0A3B4DWH6
names: Similarity
messages: Belongs to the importin alpha family.

42514:LOC108432634
gene id: 42514:LOC108432634
uniprot id: A0A3B4BQQ5
uniprot id: A0A3B4BQR0
names: Similarity
messages: Belongs to the RRP1 family.

42514:zgc:112271
gene id: 42514:zgc:112271
uniprot id: A0A3B4CJK8
names: Similarity
messages: Belongs to the BolA/IbaG family.

42514:relt
gene id: 42514:relt
uniprot id: A0A3B4CR63
names: Similarity
messages: Belongs to the RELT family.

42514:arf2a
gene id: 42514:arf2a
uniprot id: A0A3B4E3I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:stra6
gene id: 42514:stra6
uniprot id: A0A3B4DIX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:soul3
gene id: 42514:soul3
uniprot id: A0A3B4C9F0
names: Similarity
messages: Belongs to the HEBP family.

42514:LOC108437211
gene id: 42514:LOC108437211
uniprot id: A0A3B4EM23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

42514:pdcl
gene id: 42514:pdcl
uniprot id: A0A3B4CNN4
names: Similarity
messages: Belongs to the phosducin family.

42514:lmx1bb
gene id: 42514:lmx1bb
uniprot id: A0A3B4EPW0
names: Subcellular Location Annotation
messages: Nucleus

42514:si:dkey-73n8.3
gene id: 42514:si:dkey-73n8.3
uniprot id: A0A3B4CNN5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108439178
gene id: 42514:LOC108439178
uniprot id: A0A3B4CQU0
uniprot id: A0A3B4CQV0
names: Similarity
messages: Belongs to the cystatin family.

42514:actn1
gene id: 42514:actn1
uniprot id: A0A3B4BY18
names: Similarity
messages: Belongs to the alpha-actinin family.

42514:tle2b
gene id: 42514:tle2b
uniprot id: A0A3B4CPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:kcnq1.1
gene id: 42514:kcnq1.1
uniprot id: A0A3B4CFY2
uniprot id: A0A3B4E038
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum
messages: Lateral cell membrane
messages: Membrane
messages: Membrane raft

42514:c16h5orf24
gene id: 42514:c16h5orf24
uniprot id: A0A3B4D7Y6
names: Similarity
messages: Belongs to the UPF0461 family.

42514:mindy4
gene id: 42514:mindy4
uniprot id: A0A3B4E6A9
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

42514:pth1b
gene id: 42514:pth1b
uniprot id: A0A3B4DZK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

42514:si:ch211-218c6.8
gene id: 42514:si:ch211-218c6.8
uniprot id: A0A3B4CM91
names: Similarity
messages: Belongs to the Bcl-2 family.

42514:LOC108443177
gene id: 42514:LOC108443177
uniprot id: A0A3B4DM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

42514:osbpl6
gene id: 42514:osbpl6
uniprot id: A0A3B4EDH6
names: Similarity
messages: Belongs to the OSBP family.

42514:sh3bgrl
gene id: 42514:sh3bgrl
uniprot id: A0A3B4DUE4
names: Similarity
messages: Belongs to the SH3BGR family.

42514:cap1
gene id: 42514:cap1
uniprot id: A0A3B4EKU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

42514:aplp1
gene id: 42514:aplp1
uniprot id: A0A3B4DAT9
uniprot id: A0A3B4EM09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:ppp1r1c
gene id: 42514:ppp1r1c
uniprot id: A0A3B4DIN8
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

42514:tspan2b
gene id: 42514:tspan2b
uniprot id: A0A3B4CVJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:LOC108441610
gene id: 42514:LOC108441610
uniprot id: A0A3B4EQ71
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:tat
gene id: 42514:tat
uniprot id: A0A3B4E916
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

42514:LOC108431838
gene id: 42514:LOC108431838
uniprot id: A0A3B4CG99
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:LOC108431035
gene id: 42514:LOC108431035
uniprot id: A0A3B4DB80
uniprot id: A0A3B4DFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:mrps2
gene id: 42514:mrps2
uniprot id: A0A3B4DCM7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

42514:pms1
gene id: 42514:pms1
uniprot id: A0A3B4CTE1
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

42514:dlgap5
gene id: 42514:dlgap5
uniprot id: A0A3B4DMW0
names: Similarity
messages: Belongs to the SAPAP family.

42514:otpb
gene id: 42514:otpb
uniprot id: A0A3B4DFK1
names: Subcellular Location Annotation
messages: Nucleus

42514:szrd1
gene id: 42514:szrd1
uniprot id: A0A3B4CS10
names: Similarity
messages: Belongs to the SZRD1 family.

42514:LOC108427783
gene id: 42514:LOC108427783
uniprot id: A0A3B4CZM2
uniprot id: A0A3B4EBR4
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:thumpd3
gene id: 42514:thumpd3
uniprot id: A0A3B4CBW2
names: Similarity
messages: Belongs to the methyltransferase superfamily.

42514:ube2m
gene id: 42514:ube2m
uniprot id: A0A3B4D0B5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:LOC108410436
gene id: 42514:LOC108410436
uniprot id: A0A3B4D5N7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:colgalt1a
gene id: 42514:colgalt1a
uniprot id: A0A3B4CDM2
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

42514:opn4b
gene id: 42514:opn4b
uniprot id: A0A3B4DLA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:eif5a2
gene id: 42514:eif5a2
uniprot id: A0A3B4E6C3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

42514:LOC108433661
gene id: 42514:LOC108433661
uniprot id: A0A3B4DSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:si:ch211-158d24.2
gene id: 42514:si:ch211-158d24.2
uniprot id: A0A3B4DVP1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ccdc149b
gene id: 42514:ccdc149b
uniprot id: A0A3B4CCM5
names: Similarity
messages: Belongs to the CCDC149 family.

42514:caska
gene id: 42514:caska
uniprot id: A0A3B4D0D0
names: Similarity
messages: Belongs to the MAGUK family.

42514:slc9a1a
gene id: 42514:slc9a1a
uniprot id: A0A3B4DP58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane

42514:si:dkey-3h3.3
gene id: 42514:si:dkey-3h3.3
uniprot id: A0A3B4EG25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

42514:erf
gene id: 42514:erf
uniprot id: A0A3B4BVQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:atxn10
gene id: 42514:atxn10
uniprot id: A0A3B4EP41
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

42514:LOC108410484
gene id: 42514:LOC108410484
uniprot id: A0A3B4E919
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108412334
gene id: 42514:LOC108412334
uniprot id: A0A3B4DTB5
names: Subcellular Location Annotation
messages: Membrane

42514:slco2b1
gene id: 42514:slco2b1
uniprot id: A0A3B4DZQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

42514:plxna1a
gene id: 42514:plxna1a
uniprot id: A0A3B4CWW1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:stambpl1
gene id: 42514:stambpl1
uniprot id: A0A3B4DNG7
names: Similarity
messages: Belongs to the peptidase M67C family.

42514:polr1c
gene id: 42514:polr1c
uniprot id: A0A3B4BQL6
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

42514:LOC108428701
gene id: 42514:LOC108428701
uniprot id: A0A3B4DI25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

42514:zwilch
gene id: 42514:zwilch
uniprot id: A0A3B4DZB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

42514:prmt5
gene id: 42514:prmt5
uniprot id: A0A3B4CWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

42514:masp2
gene id: 42514:masp2
uniprot id: A0A3B4D0Y2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:fam110a
gene id: 42514:fam110a
uniprot id: A0A3B4CGC1
names: Similarity
messages: Belongs to the FAM110 family.

42514:LOC108414232
gene id: 42514:LOC108414232
uniprot id: A0A3B4BKN1
names: Similarity
messages: Belongs to the MHC class I family.

42514:c25h16orf87
gene id: 42514:c25h16orf87
uniprot id: A0A3B4CCU5
names: Similarity
messages: Belongs to the UPF0547 family.

42514:camk2g1
gene id: 42514:camk2g1
uniprot id: A0A3B4CY27
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

42514:nrg2b
gene id: 42514:nrg2b
uniprot id: A0A3B4BQT5
uniprot id: A0A3B4BTY5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:wnt4
gene id: 42514:wnt4
uniprot id: A0A3B4BY68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:grik1b
gene id: 42514:grik1b
uniprot id: A0A3B4D3N7
uniprot id: A0A3B4D6B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:sema3c
gene id: 42514:sema3c
uniprot id: A0A3B4DN41
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dip2bb
gene id: 42514:dip2bb
uniprot id: A0A3B4CD85
uniprot id: A0A3B4DY37
uniprot id: A0A3B4DY97
uniprot id: A0A3B4DZ95
names: Similarity
messages: Belongs to the DIP2 family.

42514:mlst8
gene id: 42514:mlst8
uniprot id: A0A3B4C031
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of TORC1 complex. Part of the TORC2 complex.
messages: Subunit of TORC1 and TORC2, which regulate cell growth and survival in response to nutrient and hormonal signals.

42514:nkx1.2lb
gene id: 42514:nkx1.2lb
uniprot id: A0A3B4E3X9
names: Subcellular Location Annotation
messages: Nucleus

42514:sqstm1
gene id: 42514:sqstm1
uniprot id: A0A3B4E9J3
names: Subcellular Location Annotation
messages: autophagosome

42514:unc5b
gene id: 42514:unc5b
uniprot id: A0A3B4DK03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

42514:LOC108437014
gene id: 42514:LOC108437014
uniprot id: A0A3B4C5Y5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:trak2
gene id: 42514:trak2
uniprot id: A0A3B4DYL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

42514:rgmd
gene id: 42514:rgmd
uniprot id: A0A3B4C6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

42514:LOC108411777
gene id: 42514:LOC108411777
uniprot id: A0A3B4EB42
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:atad1b
gene id: 42514:atad1b
uniprot id: A0A3B4BW37
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:cga
gene id: 42514:cga
uniprot id: A0A3B4DL12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer of an alpha and a beta chain.
messages: Secreted

42514:nkx2.5
gene id: 42514:nkx2.5
uniprot id: A0A3B4BYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

42514:LOC108434426
gene id: 42514:LOC108434426
uniprot id: A0A3B4CS35
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

42514:rusf1
gene id: 42514:rusf1
uniprot id: A0A3B4DYG7
names: Similarity
messages: Belongs to the RUS1 family.

42514:trhr2
gene id: 42514:trhr2
uniprot id: A0A3B4CLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

42514:mbd4
gene id: 42514:mbd4
uniprot id: A0A3B4BMG7
names: Subcellular Location Annotation
messages: Nucleus

42514:ogg1
gene id: 42514:ogg1
uniprot id: A0A3B4ER33
names: Similarity
messages: Belongs to the type-1 OGG1 family.

42514:LOC108430549
gene id: 42514:LOC108430549
uniprot id: A0A3B4CW84
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:pgm2l1
gene id: 42514:pgm2l1
uniprot id: A0A3B4C0I5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

42514:mef2aa
gene id: 42514:mef2aa
uniprot id: A0A3B4D5G7
uniprot id: A0A3B4D5Q4
uniprot id: A0A3B4EFL4
uniprot id: A0A3B4EJE3
names: Subcellular Location Annotation
messages: Nucleus

42514:nmnat3
gene id: 42514:nmnat3
uniprot id: A0A3B4EHP1
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

42514:slc20a2
gene id: 42514:slc20a2
uniprot id: A0A3B4C267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport.

42514:LOC108413439
gene id: 42514:LOC108413439
uniprot id: A0A3B4CXW8
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:sept3
gene id: 42514:sept3
uniprot id: A0A3B4D166
uniprot id: A0A3B4D184
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm

42514:slc6a18
gene id: 42514:slc6a18
uniprot id: A0A3B4DAM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:gna14a
gene id: 42514:gna14a
uniprot id: A0A3B4E5Y0
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

42514:LOC108440219
gene id: 42514:LOC108440219
uniprot id: A0A3B4C3Q0
names: Similarity
messages: Belongs to the globin family.

42514:LOC108431969
gene id: 42514:LOC108431969
uniprot id: A0A3B4DM67
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

42514:spc24
gene id: 42514:spc24
uniprot id: A0A3B4D3Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

42514:slc35c2
gene id: 42514:slc35c2
uniprot id: A0A3B4E4R7
names: Subcellular Location Annotation
messages: Membrane

42514:atp6v0b
gene id: 42514:atp6v0b
uniprot id: A0A3B4DL77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

42514:wnt7aa
gene id: 42514:wnt7aa
uniprot id: A0A3B4BPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

42514:fign
gene id: 42514:fign
uniprot id: A0A3B4EDB6
names: Similarity
messages: Belongs to the AAA ATPase family.

42514:nploc4
gene id: 42514:nploc4
uniprot id: A0A3B4DSR4
names: Similarity
messages: Belongs to the NPL4 family.

42514:vwc2
gene id: 42514:vwc2
uniprot id: A0A3B4EQN7
names: Subcellular Location Annotation
messages: Synapse

42514:inpp4b
gene id: 42514:inpp4b
uniprot id: A0A3B4DDF6
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

42514:il17c
gene id: 42514:il17c
uniprot id: A0A3B4E4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

42514:fam114a2
gene id: 42514:fam114a2
uniprot id: A0A3B4E1X6
names: Similarity
messages: Belongs to the FAM114 family.

42514:pfkfb4a
gene id: 42514:pfkfb4a
uniprot id: A0A3B4CD00
uniprot id: A0A3B4E1V5
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

42514:slc23a1
gene id: 42514:slc23a1
uniprot id: A0A3B4CBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

42514:rpl11
gene id: 42514:rpl11
uniprot id: A0A3B4EH11
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

42514:eogt
gene id: 42514:eogt
uniprot id: A0A3B4CDL4
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

42514:nrd1b
gene id: 42514:nrd1b
uniprot id: A0A3B4CWD8
names: Similarity
messages: Belongs to the peptidase M16 family.

42514:pou2f3
gene id: 42514:pou2f3
uniprot id: A0A3B4E212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

42514:LOC108438288
gene id: 42514:LOC108438288
uniprot id: A0A3B4D9R7
uniprot id: A0A3B4EL36
names: Subcellular Location Annotation
messages: Membrane

42514:hmgcll1
gene id: 42514:hmgcll1
uniprot id: A0A3B4D3K1
uniprot id: A0A3B4EDI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

42514:slc7a3a
gene id: 42514:slc7a3a
uniprot id: A0A3B4C9G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

42514:nmd3
gene id: 42514:nmd3
uniprot id: A0A3B4BTS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

42514:ip6k2a
gene id: 42514:ip6k2a
uniprot id: A0A3B4CHC4
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:cnfn
gene id: 42514:cnfn
uniprot id: A0A3B4CSR0
names: Similarity
messages: Belongs to the cornifelin family.

42514:unc45b
gene id: 42514:unc45b
uniprot id: A0A3B4E5D4
names: Subcellular Location Annotation
messages: perinuclear region

42514:LOC108442070
gene id: 42514:LOC108442070
uniprot id: A0A3B4DIR6
names: Similarity
messages: Belongs to the acylphosphatase family.

42514:eaf1
gene id: 42514:eaf1
uniprot id: A0A3B4BX14
names: Similarity
messages: Belongs to the EAF family.

42514:lsm6
gene id: 42514:lsm6
uniprot id: A0A3B4E6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

42514:si:ch211-201h21.5
gene id: 42514:si:ch211-201h21.5
uniprot id: A0A3B4EK92
names: Similarity
messages: Belongs to the IUNH family.

42514:cct4
gene id: 42514:cct4
uniprot id: A0A3B4DVE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

42514:LOC108434294
gene id: 42514:LOC108434294
uniprot id: A0A3B4DMK2
names: Similarity
messages: Belongs to the MHC class I family.

42514:LOC108425280
gene id: 42514:LOC108425280
uniprot id: A0A3B4BMU4
names: Subcellular Location Annotation
messages: Nucleus

42514:stc2a
gene id: 42514:stc2a
uniprot id: A0A3B4BZ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.
messages: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.

42514:narfl
gene id: 42514:narfl
uniprot id: A0A3B4EJV1
names: Similarity
messages: Belongs to the NARF family.

42514:cdk20
gene id: 42514:cdk20
uniprot id: A0A3B4EIG4
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:tbl1xr1b
gene id: 42514:tbl1xr1b
uniprot id: A0A3B4CI55
names: Similarity
messages: Belongs to the WD repeat EBI family.

42514:si:ch1073-429i10.3
gene id: 42514:si:ch1073-429i10.3
uniprot id: A0A3B4BZQ6
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:slc5a12
gene id: 42514:slc5a12
uniprot id: A0A3B4BMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:chrm2b
gene id: 42514:chrm2b
uniprot id: A0A3B4E714
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

42514:shmt2
gene id: 42514:shmt2
uniprot id: A0A3B4CMA9
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

42514:im:7138535
gene id: 42514:im:7138535
uniprot id: A0A3B4CTM5
names: Similarity
messages: Belongs to the FAM98 family.

42514:plin6
gene id: 42514:plin6
uniprot id: A0A3B4BNC3
names: Similarity
messages: Belongs to the perilipin family.

42514:LOC108435742
gene id: 42514:LOC108435742
uniprot id: A0A3B4CKQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

42514:chst3a
gene id: 42514:chst3a
uniprot id: A0A3B4DGP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

42514:edem2
gene id: 42514:edem2
uniprot id: A0A3B4E1E1
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

42514:nsfl1c
gene id: 42514:nsfl1c
uniprot id: A0A3B4C6P4
names: Subcellular Location Annotation
messages: Golgi stack

42514:pleca
gene id: 42514:pleca
uniprot id: A0A3B4CWZ5
names: Subcellular Location Annotation
messages: cytoskeleton

42514:ebf1a
gene id: 42514:ebf1a
uniprot id: A0A3B4CPU8
uniprot id: A0A3B4CPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

42514:znrf3
gene id: 42514:znrf3
uniprot id: A0A3B4D4K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

42514:tmem121aa
gene id: 42514:tmem121aa
uniprot id: A0A3B4D7S2
names: Similarity
messages: Belongs to the TMEM121 family.

42514:LOC108436089
gene id: 42514:LOC108436089
uniprot id: A0A3B4EF33
names: Subcellular Location Annotation
messages: cytoskeleton

42514:tha1
gene id: 42514:tha1
uniprot id: A0A3B4D6S0
names: Similarity
messages: Belongs to the threonine aldolase family.

42514:washc5
gene id: 42514:washc5
uniprot id: A0A3B4E2H1
names: Similarity
messages: Belongs to the strumpellin family.

42514:numb
gene id: 42514:numb
uniprot id: A0A3B4DNU1
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

42514:gpr82
gene id: 42514:gpr82
uniprot id: A0A3B4ED19
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:rspo1
gene id: 42514:rspo1
uniprot id: A0A3B4DBG6
names: Similarity
messages: Belongs to the R-spondin family.

42514:LOC108426117
gene id: 42514:LOC108426117
uniprot id: A0A3B4DE34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:zgc:162707
gene id: 42514:zgc:162707
uniprot id: A0A3B4C8B3
names: Similarity
messages: Belongs to the UPF0524 family.

42514:znf711
gene id: 42514:znf711
uniprot id: A0A3B4DEX0
names: Subcellular Location Annotation
messages: Nucleus

42514:gucy2d
gene id: 42514:gucy2d
uniprot id: A0A3B4C8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

42514:grb10a
gene id: 42514:grb10a
uniprot id: A0A3B4C1P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

42514:nampt1
gene id: 42514:nampt1
uniprot id: A0A3B4EHX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

42514:cmtm7
gene id: 42514:cmtm7
uniprot id: A0A3B4CWH1
names: Subcellular Location Annotation
messages: Membrane

42514:st8sia3
gene id: 42514:st8sia3
uniprot id: A0A3B4BWD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:taf10
gene id: 42514:taf10
uniprot id: A0A3B4EDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

42514:soul4
gene id: 42514:soul4
uniprot id: A0A3B4C024
names: Similarity
messages: Belongs to the HEBP family.

42514:tbx1
gene id: 42514:tbx1
uniprot id: A0A3B4CAP2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:LOC108426548
gene id: 42514:LOC108426548
uniprot id: A0A3B4D1G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon

42514:slc7a5
gene id: 42514:slc7a5
uniprot id: A0A3B4DRT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

42514:ak1
gene id: 42514:ak1
uniprot id: A0A3B4DEV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

42514:eif1ad
gene id: 42514:eif1ad
uniprot id: A0A3B4DKQ3
names: Similarity
messages: Belongs to the EIF1AD family.

42514:slc43a3a
gene id: 42514:slc43a3a
uniprot id: A0A3B4CFA4
names: Subcellular Location Annotation
messages: Membrane

42514:b3gnt2a
gene id: 42514:b3gnt2a
uniprot id: A0A3B4CB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:si:ch211-251b21.1
gene id: 42514:si:ch211-251b21.1
uniprot id: A0A3B4D8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:zgc:165573
gene id: 42514:zgc:165573
uniprot id: A0A3B4DDI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYSTM1 family.
messages: Membrane

42514:marveld2a
gene id: 42514:marveld2a
uniprot id: A0A3B4C2H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

42514:nusap1
gene id: 42514:nusap1
uniprot id: A0A3B4C7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

42514:cops7a
gene id: 42514:cops7a
uniprot id: A0A3B4ECM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

42514:grin3bb
gene id: 42514:grin3bb
uniprot id: A0A3B4EIN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

42514:usp14
gene id: 42514:usp14
uniprot id: A0A3B4D0Y0
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

42514:capn3b
gene id: 42514:capn3b
uniprot id: A0A3B4C6L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

42514:lamc3
gene id: 42514:lamc3
uniprot id: A0A3B4CMF3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

42514:setd7
gene id: 42514:setd7
uniprot id: A0A3B4DFK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

42514:LOC108438085
gene id: 42514:LOC108438085
uniprot id: A0A3B4DQ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

42514:gnsb
gene id: 42514:gnsb
uniprot id: A0A3B4EJ93
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:LOC108425053
gene id: 42514:LOC108425053
uniprot id: A0A3B4E2L0
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

42514:LOC108424881
gene id: 42514:LOC108424881
uniprot id: A0A3B4D3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus speckle

42514:kcnk1b
gene id: 42514:kcnk1b
uniprot id: A0A3B4DY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

42514:ppdpfb
gene id: 42514:ppdpfb
uniprot id: A0A3B4E2F9
names: Similarity
messages: Belongs to the PPDPF family.

42514:mcur1
gene id: 42514:mcur1
uniprot id: A0A3B4E5U4
names: Similarity
messages: Belongs to the CCDC90 family.

42514:nf2a
gene id: 42514:nf2a
uniprot id: A0A3B4D2T5
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

42514:magoh
gene id: 42514:magoh
uniprot id: A0A3B4EKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

42514:zgc:162816
gene id: 42514:zgc:162816
uniprot id: A0A3B4CFQ9
names: Similarity
messages: Belongs to the DSD1 family.

42514:LOC108443209
gene id: 42514:LOC108443209
uniprot id: A0A3B4BQD3
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

42514:barx2
gene id: 42514:barx2
uniprot id: A0A3B4C8X2
names: Subcellular Location Annotation
messages: Nucleus

42514:agbl4
gene id: 42514:agbl4
uniprot id: A0A3B4E1H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

42514:sap30l
gene id: 42514:sap30l
uniprot id: A0A3B4CUQ2
names: Similarity
messages: Belongs to the SAP30 family.

42514:snx10b
gene id: 42514:snx10b
uniprot id: A0A3B4BSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

42514:mthfs
gene id: 42514:mthfs
uniprot id: A0A3B4DW17
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

42514:chrna2a
gene id: 42514:chrna2a
uniprot id: A0A3B4BPM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:LOC108434549
gene id: 42514:LOC108434549
uniprot id: A0A3B4EE55
names: Subcellular Location Annotation
messages: Membrane

42514:ssr2
gene id: 42514:ssr2
uniprot id: A0A3B4DQT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

42514:brpf3a
gene id: 42514:brpf3a
uniprot id: A0A3B4E682
names: Subcellular Location Annotation
messages: Nucleus

42514:jakmip2
gene id: 42514:jakmip2
uniprot id: A0A3B4E0E3
names: Similarity
messages: Belongs to the JAKMIP family.

42514:fam136a
gene id: 42514:fam136a
uniprot id: A0A3B4DND9
names: Similarity
messages: Belongs to the FAM136 family.

42514:LOC108426442
gene id: 42514:LOC108426442
uniprot id: A0A3B4EJL4
names: Function
messages: May be involved in neurite outgrowth.

42514:nr2f1a
gene id: 42514:nr2f1a
uniprot id: A0A3B4EJJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:glg1a
gene id: 42514:glg1a
uniprot id: A0A3B4CET0
uniprot id: A0A3B4CJ03
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

42514:b3gnt7
gene id: 42514:b3gnt7
uniprot id: A0A3B4CNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:prdx2
gene id: 42514:prdx2
uniprot id: A0A3B4CWX0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

42514:cdc42bpab
gene id: 42514:cdc42bpab
uniprot id: A0A3B4BUB4
uniprot id: A0A3B4DI60
uniprot id: A0A3B4DKU2
uniprot id: A0A3B4DM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: lamellipodium

42514:ppp1r2
gene id: 42514:ppp1r2
uniprot id: A0A3B4DNT3
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

42514:mbtd1
gene id: 42514:mbtd1
uniprot id: A0A3B4BRV4
uniprot id: A0A3B4BV20
names: Subcellular Location Annotation
messages: Nucleus

42514:sec23a
gene id: 42514:sec23a
uniprot id: A0A3B4BTW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

42514:LOC108426971
gene id: 42514:LOC108426971
uniprot id: A0A3B4BV72
names: Similarity
messages: Belongs to the TCAF family.

42514:LOC108417215
gene id: 42514:LOC108417215
uniprot id: A0A3B4DS60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:LOC108443081
gene id: 42514:LOC108443081
uniprot id: A0A3B4C9D2
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:tnfrsf9a
gene id: 42514:tnfrsf9a
uniprot id: A0A3B4E9I0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ptger3
gene id: 42514:ptger3
uniprot id: A0A3B4C207
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:slc49a4
gene id: 42514:slc49a4
uniprot id: A0A3B4EN17
names: Subcellular Location Annotation
messages: Membrane

42514:fnta
gene id: 42514:fnta
uniprot id: A0A3B4D3U9
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

42514:c28h1orf174
gene id: 42514:c28h1orf174
uniprot id: A0A3B4CNW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

42514:ippk
gene id: 42514:ippk
uniprot id: A0A3B4BS10
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

42514:gtf2a1
gene id: 42514:gtf2a1
uniprot id: A0A3B4BN47
uniprot id: A0A3B4BQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

42514:dbnlb
gene id: 42514:dbnlb
uniprot id: A0A3B4CY89
uniprot id: A0A3B4CZW2
uniprot id: A0A3B4ECZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

42514:LOC108436201
gene id: 42514:LOC108436201
uniprot id: A0A3B4E479
names: Subcellular Location Annotation
messages: Nucleus

42514:myo3b
gene id: 42514:myo3b
uniprot id: A0A3B4E986
uniprot id: A0A3B4E996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

42514:LOC108443230
gene id: 42514:LOC108443230
uniprot id: A0A3B4DK04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:ifi30
gene id: 42514:ifi30
uniprot id: A0A3B4BRU5
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

42514:supv3l1
gene id: 42514:supv3l1
uniprot id: A0A3B4CLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

42514:pfkla
gene id: 42514:pfkla
uniprot id: A0A3B4CEW0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:gabra5
gene id: 42514:gabra5
uniprot id: A0A3B4C5P9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:gata3
gene id: 42514:gata3
uniprot id: A0A3B4DKS2
names: Subcellular Location Annotation
messages: Nucleus

42514:atp6v0a1a
gene id: 42514:atp6v0a1a
uniprot id: A0A3B4CBA2
uniprot id: A0A3B4DYF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

42514:LOC108431133
gene id: 42514:LOC108431133
uniprot id: A0A3B4D1N4
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:asl
gene id: 42514:asl
uniprot id: A0A3B4CBM0
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

42514:polr3d
gene id: 42514:polr3d
uniprot id: A0A3B4D041
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108434802
gene id: 42514:LOC108434802
uniprot id: A0A3B4DZV9
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

42514:mmgt1
gene id: 42514:mmgt1
uniprot id: A0A3B4CTR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.

42514:znf687b
gene id: 42514:znf687b
uniprot id: A0A3B4BWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

42514:trappc5
gene id: 42514:trappc5
uniprot id: A0A3B4EFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

42514:pgm2
gene id: 42514:pgm2
uniprot id: A0A3B4CP42
names: Similarity
messages: Belongs to the phosphohexose mutase family.

42514:minpp1b
gene id: 42514:minpp1b
uniprot id: A0A3B4BWJ7
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

42514:rab4b
gene id: 42514:rab4b
uniprot id: A0A3B4BXK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

42514:abcg4b
gene id: 42514:abcg4b
uniprot id: A0A3B4D5G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

42514:kdr
gene id: 42514:kdr
uniprot id: A0A3B4BUD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:ppfia2
gene id: 42514:ppfia2
uniprot id: A0A3B4C5X8
uniprot id: A0A3B4C6V3
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

42514:lix1
gene id: 42514:lix1
uniprot id: A0A3B4D723
names: Similarity
messages: Belongs to the LIX1 family.

42514:s1pr4
gene id: 42514:s1pr4
uniprot id: A0A3B4C025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

42514:npm1b
gene id: 42514:npm1b
uniprot id: A0A3B4D3V7
names: Similarity
messages: Belongs to the nucleoplasmin family.

42514:ppp1r14ab
gene id: 42514:ppp1r14ab
uniprot id: A0A3B4C118
names: Similarity
messages: Belongs to the PP1 inhibitor family.

42514:camkmt
gene id: 42514:camkmt
uniprot id: A0A3B4DYA3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:irf2
gene id: 42514:irf2
uniprot id: A0A3B4EEY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:crb2b
gene id: 42514:crb2b
uniprot id: A0A3B4BLC3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tmem218
gene id: 42514:tmem218
uniprot id: A0A3B4E8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

42514:setd3
gene id: 42514:setd3
uniprot id: A0A3B4EAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
messages: Cytoplasm

42514:fxyd1
gene id: 42514:fxyd1
uniprot id: A0A3B4EK80
names: Similarity
messages: Belongs to the FXYD family.

42514:atxn2l
gene id: 42514:atxn2l
uniprot id: A0A3B4CEI9
uniprot id: A0A3B4DZ62
names: Similarity
messages: Belongs to the ataxin-2 family.

42514:tdgf1
gene id: 42514:tdgf1
uniprot id: A0A3B4CPG0
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.

42514:lepb
gene id: 42514:lepb
uniprot id: A0A3B4DLB7
names: Similarity
messages: Belongs to the leptin family.

42514:tph2
gene id: 42514:tph2
uniprot id: A0A3B4CLG9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

42514:rev1
gene id: 42514:rev1
uniprot id: A0A3B4BY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

42514:hsc70
gene id: 42514:hsc70
uniprot id: A0A3B4CCA1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

42514:cd247
gene id: 42514:cd247
uniprot id: A0A3B4DS25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Membrane

42514:sf3b3
gene id: 42514:sf3b3
uniprot id: A0A3B4CD56
names: Subcellular Location Annotation
messages: Nucleus

42514:clu
gene id: 42514:clu
uniprot id: A0A3B4BZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol

42514:LOC108435089
gene id: 42514:LOC108435089
uniprot id: A0A3B4CXM3
names: Subcellular Location Annotation
messages: Membrane

42514:kdm4c
gene id: 42514:kdm4c
uniprot id: A0A3B4E7C1
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

42514:tmem214
gene id: 42514:tmem214
uniprot id: A0A3B4CV71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM214 family.
messages: Constitutively interacts with CASP4; required for the localization of procaspase 4 to the ER.
messages: Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108426757
gene id: 42514:LOC108426757
uniprot id: A0A3B4EGB7
uniprot id: A0A3B4EJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

42514:LOC108424161
gene id: 42514:LOC108424161
uniprot id: A0A3B4D4F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

42514:xpnpep1
gene id: 42514:xpnpep1
uniprot id: A0A3B4CJX0
uniprot id: A0A3B4E2Z5
names: Similarity
messages: Belongs to the peptidase M24B family.

42514:iscu
gene id: 42514:iscu
uniprot id: A0A3B4C0Y8
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

42514:LOC108426323
gene id: 42514:LOC108426323
uniprot id: A0A3B4BX50
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

42514:bscl2l
gene id: 42514:bscl2l
uniprot id: A0A3B4DBJ8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108443018
gene id: 42514:LOC108443018
uniprot id: A0A3B4E0A9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

42514:ube2e3
gene id: 42514:ube2e3
uniprot id: A0A3B4EID8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:zgc:112148
gene id: 42514:zgc:112148
uniprot id: A0A3B4DH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

42514:msx2b
gene id: 42514:msx2b
uniprot id: A0A3B4ELP2
names: Subcellular Location Annotation
messages: Nucleus

42514:fzd4
gene id: 42514:fzd4
uniprot id: A0A3B4EBT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Membrane

42514:dok1b
gene id: 42514:dok1b
uniprot id: A0A3B4BXG5
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

42514:LOC108433858
gene id: 42514:LOC108433858
uniprot id: A0A3B4DE92
names: Similarity
messages: Belongs to the MS4A family.

42514:alg6
gene id: 42514:alg6
uniprot id: A0A3B4DMV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:LOC108430725
gene id: 42514:LOC108430725
uniprot id: A0A3B4CP46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

42514:ncapg
gene id: 42514:ncapg
uniprot id: A0A3B4BZX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

42514:vgll2a
gene id: 42514:vgll2a
uniprot id: A0A3B4CBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

42514:tnk2a
gene id: 42514:tnk2a
uniprot id: A0A3B4BPU4
uniprot id: A0A3B4BTB2
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

42514:rad23aa
gene id: 42514:rad23aa
uniprot id: A0A3B4CSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

42514:tmprss4b
gene id: 42514:tmprss4b
uniprot id: A0A3B4C500
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dhrs11a
gene id: 42514:dhrs11a
uniprot id: A0A3B4DKR9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:wscd2
gene id: 42514:wscd2
uniprot id: A0A3B4DNH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

42514:LOC108412459
gene id: 42514:LOC108412459
uniprot id: A0A3B4BZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

42514:LOC108442750
gene id: 42514:LOC108442750
uniprot id: A0A3B4DGQ7
names: Subcellular Location Annotation
messages: Membrane

42514:enkd1
gene id: 42514:enkd1
uniprot id: A0A3B4DF18
names: Subcellular Location Annotation
messages: cilium axoneme

42514:camk2n1a
gene id: 42514:camk2n1a
uniprot id: A0A3B4CVM5
names: Similarity
messages: Belongs to the CAMK2N family.

42514:olah
gene id: 42514:olah
uniprot id: A0A3B4BRY5
names: Similarity
messages: Belongs to the thioesterase family.

42514:palmdb
gene id: 42514:palmdb
uniprot id: A0A3B4CYM0
names: Similarity
messages: Belongs to the paralemmin family.

42514:map2k5
gene id: 42514:map2k5
uniprot id: A0A3B4DZA1
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108424250
gene id: 42514:LOC108424250
uniprot id: A0A3B4CF67
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

42514:LOC108415028
gene id: 42514:LOC108415028
uniprot id: A0A3B4EMW3
names: Subcellular Location Annotation
messages: Membrane

42514:ttll1
gene id: 42514:ttll1
uniprot id: A0A3B4ERM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin polyglutamylase family.
messages: cilium basal body

42514:cenpn
gene id: 42514:cenpn
uniprot id: A0A3B4DMJ0
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

42514:bdnf
gene id: 42514:bdnf
uniprot id: A0A3B4CLU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

42514:adgrl4
gene id: 42514:adgrl4
uniprot id: A0A3B4CFJ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:orc2
gene id: 42514:orc2
uniprot id: A0A3B4BRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

42514:pfkmb
gene id: 42514:pfkmb
uniprot id: A0A3B4DZB5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108429652
gene id: 42514:LOC108429652
uniprot id: A0A3B4CHA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:fkbp6
gene id: 42514:fkbp6
uniprot id: A0A3B4E0T7
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

42514:arglu1a
gene id: 42514:arglu1a
uniprot id: A0A3B4DW77
names: Similarity
messages: Belongs to the UPF0430 family.

42514:acer2
gene id: 42514:acer2
uniprot id: A0A3B4E6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

42514:mtmr10
gene id: 42514:mtmr10
uniprot id: A0A3B4EDA8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

42514:bcar1
gene id: 42514:bcar1
uniprot id: A0A3B4CKQ5
uniprot id: A0A3B4E3Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

42514:wash1
gene id: 42514:wash1
uniprot id: A0A3B4DLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

42514:c28h9orf116
gene id: 42514:c28h9orf116
uniprot id: A0A3B4D284
names: Subcellular Location Annotation
messages: cilium axoneme

42514:brpf3b
gene id: 42514:brpf3b
uniprot id: A0A3B4CG74
names: Subcellular Location Annotation
messages: Nucleus

42514:ap3b1a
gene id: 42514:ap3b1a
uniprot id: A0A3B4DAZ1
uniprot id: A0A3B4DCA8
uniprot id: A0A3B4DCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

42514:siah2l
gene id: 42514:siah2l
uniprot id: A0A3B4CFI2
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

42514:slc7a14b
gene id: 42514:slc7a14b
uniprot id: A0A3B4DLS0
names: Subcellular Location Annotation
messages: Membrane

42514:cltcl1
gene id: 42514:cltcl1
uniprot id: A0A3B4BSE2
uniprot id: A0A3B4DMQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

42514:suv39h1a
gene id: 42514:suv39h1a
uniprot id: A0A3B4CHK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

42514:ltc4s
gene id: 42514:ltc4s
uniprot id: A0A3B4E8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:klc3
gene id: 42514:klc3
uniprot id: A0A3B4BWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

42514:wfikkn2b
gene id: 42514:wfikkn2b
uniprot id: A0A3B4DIK4
names: Similarity
messages: Belongs to the WFIKKN family.

42514:cacng7a
gene id: 42514:cacng7a
uniprot id: A0A3B4DB67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

42514:golph3
gene id: 42514:golph3
uniprot id: A0A3B4D6K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

42514:LOC108439315
gene id: 42514:LOC108439315
uniprot id: A0A3B4DDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:kitb
gene id: 42514:kitb
uniprot id: A0A3B4DKD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:crls1
gene id: 42514:crls1
uniprot id: A0A3B4BK27
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

42514:LOC108433660
gene id: 42514:LOC108433660
uniprot id: A0A3B4C4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:cdkl1
gene id: 42514:cdkl1
uniprot id: A0A3B4C858
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108439637
gene id: 42514:LOC108439637
uniprot id: A0A3B4CCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

42514:LOC108425006
gene id: 42514:LOC108425006
uniprot id: A0A3B4CRI6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

42514:hbs1l
gene id: 42514:hbs1l
uniprot id: A0A3B4EJL0
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Interacts with the SKI complex.

42514:pias1a
gene id: 42514:pias1a
uniprot id: A0A3B4CEX5
names: Similarity
messages: Belongs to the PIAS family.

42514:atp1b3b
gene id: 42514:atp1b3b
uniprot id: A0A3B4C2M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

42514:sgcg
gene id: 42514:sgcg
uniprot id: A0A3B4DNC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

42514:kcnv2a
gene id: 42514:kcnv2a
uniprot id: A0A3B4D647
names: Subcellular Location Annotation
messages: Membrane

42514:pld2
gene id: 42514:pld2
uniprot id: A0A3B4C926
names: Similarity
messages: Belongs to the phospholipase D family.

42514:sst1.2
gene id: 42514:sst1.2
uniprot id: A0A3B4DX75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted
messages: Somatostatin inhibits the release of somatotropin.

42514:gprc5bb
gene id: 42514:gprc5bb
uniprot id: A0A3B4C4W4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:lhfpl6
gene id: 42514:lhfpl6
uniprot id: A0A3B4BPZ1
names: Subcellular Location Annotation
messages: Membrane

42514:si:ch73-206p6.1
gene id: 42514:si:ch73-206p6.1
uniprot id: A0A3B4DGH2
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

42514:crebl2
gene id: 42514:crebl2
uniprot id: A0A3B4DCQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

42514:gpc5c
gene id: 42514:gpc5c
uniprot id: A0A3B4C2A3
uniprot id: A0A3B4DQW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

42514:aco2
gene id: 42514:aco2
uniprot id: A0A3B4DXS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

42514:prdm16
gene id: 42514:prdm16
uniprot id: A0A3B4EKC3
names: Subcellular Location Annotation
messages: Nucleus

42514:zmpste24
gene id: 42514:zmpste24
uniprot id: A0A3B4EM44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

42514:stac
gene id: 42514:stac
uniprot id: A0A3B4CZ34
names: Subcellular Location Annotation
messages: sarcolemma

42514:si:dkey-190g11.3
gene id: 42514:si:dkey-190g11.3
uniprot id: A0A3B4CC84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

42514:gdap2
gene id: 42514:gdap2
uniprot id: A0A3B4C2M3
names: Similarity
messages: Belongs to the GDAP2 family.

42514:os9
gene id: 42514:os9
uniprot id: A0A3B4DY78
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

42514:fabp10a
gene id: 42514:fabp10a
uniprot id: A0A3B4DK73
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

42514:entpd4
gene id: 42514:entpd4
uniprot id: A0A3B4CQE8
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

42514:ncam1b
gene id: 42514:ncam1b
uniprot id: A0A3B4C6Q3
uniprot id: A0A3B4DRD0
uniprot id: A0A3B4DTU8
names: Function
messages: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

42514:prickle1a
gene id: 42514:prickle1a
uniprot id: A0A3B4CNI1
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

42514:postna
gene id: 42514:postna
uniprot id: A0A3B4CGQ5
uniprot id: A0A3B4E3G2
names: Subcellular Location Annotation
messages: extracellular matrix

42514:gng7
gene id: 42514:gng7
uniprot id: A0A3B4DZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:fgf2
gene id: 42514:fgf2
uniprot id: A0A3B4CZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Nucleus
messages: Secreted

42514:trmt13
gene id: 42514:trmt13
uniprot id: A0A3B4CZN5
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

42514:pdgfc
gene id: 42514:pdgfc
uniprot id: A0A3B4CRC6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:dnm3b
gene id: 42514:dnm3b
uniprot id: A0A3B4BTU2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

42514:lmnb1
gene id: 42514:lmnb1
uniprot id: A0A3B4BP03
names: Similarity
messages: Belongs to the intermediate filament family.

42514:ninj1
gene id: 42514:ninj1
uniprot id: A0A3B4DNH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

42514:LOC108434139
gene id: 42514:LOC108434139
uniprot id: A0A3B4C634
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:LOC108414120
gene id: 42514:LOC108414120
uniprot id: A0A3B4DH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

42514:snrpa
gene id: 42514:snrpa
uniprot id: A0A3B4DE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

42514:hkdc1
gene id: 42514:hkdc1
uniprot id: A0A3B4E5W3
names: Similarity
messages: Belongs to the hexokinase family.

42514:LOC108433284
gene id: 42514:LOC108433284
uniprot id: A0A3B4EL34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:nr1h5
gene id: 42514:nr1h5
uniprot id: A0A3B4CF61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:pde3b
gene id: 42514:pde3b
uniprot id: A0A3B4CHN7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:pkma
gene id: 42514:pkma
uniprot id: A0A3B4DDN2
names: Similarity
messages: Belongs to the pyruvate kinase family.

42514:psmd12
gene id: 42514:psmd12
uniprot id: A0A3B4DDI3
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

42514:sarm1
gene id: 42514:sarm1
uniprot id: A0A3B4DM29
names: Similarity
messages: Belongs to the SARM1 family.

42514:dtymk
gene id: 42514:dtymk
uniprot id: A0A3B4EQS0
names: Similarity
messages: Belongs to the thymidylate kinase family.

42514:efna5b
gene id: 42514:efna5b
uniprot id: A0A3B4BSG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:itga4
gene id: 42514:itga4
uniprot id: A0A3B4D5K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

42514:gngt2b
gene id: 42514:gngt2b
uniprot id: A0A3B4D7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:smarcad1a
gene id: 42514:smarcad1a
uniprot id: A0A3B4DNT6
names: Subcellular Location Annotation
messages: Chromosome

42514:LOC108431486
gene id: 42514:LOC108431486
uniprot id: A0A3B4BW89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NALF family.
messages: Membrane

42514:actc1a
gene id: 42514:actc1a
uniprot id: A0A3B4EEV7
names: Similarity
messages: Belongs to the actin family.

42514:pym1
gene id: 42514:pym1
uniprot id: A0A3B4CQE7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

42514:kcnh1a
gene id: 42514:kcnh1a
uniprot id: A0A3B4EKV0
names: Subcellular Location Annotation
messages: Membrane

42514:sub1a
gene id: 42514:sub1a
uniprot id: A0A3B4DL45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Nucleus

42514:pnx
gene id: 42514:pnx
uniprot id: A0A3B4D7E8
names: Subcellular Location Annotation
messages: Nucleus

42514:vars2
gene id: 42514:vars2
uniprot id: A0A3B4EJX3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:si:dkey-234i14.3
gene id: 42514:si:dkey-234i14.3
uniprot id: A0A3B4E264
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:sh3gl3a
gene id: 42514:sh3gl3a
uniprot id: A0A3B4CH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

42514:kcnh3
gene id: 42514:kcnh3
uniprot id: A0A3B4D7Y1
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

42514:paqr3b
gene id: 42514:paqr3b
uniprot id: A0A3B4E534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:LOC108412385
gene id: 42514:LOC108412385
uniprot id: A0A3B4DQM5
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:trpm5
gene id: 42514:trpm5
uniprot id: A0A3B4CH88
names: Subcellular Location Annotation
messages: Membrane

42514:arhgef1a
gene id: 42514:arhgef1a
uniprot id: A0A3B4C1M0
uniprot id: A0A3B4DS02
uniprot id: A0A3B4DS37
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108432484
gene id: 42514:LOC108432484
uniprot id: A0A3B4C1S7
uniprot id: A0A3B4C2X0
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108425693
gene id: 42514:LOC108425693
uniprot id: A0A3B4DYD5
names: Subcellular Location Annotation
messages: Nucleus

42514:ppap2d
gene id: 42514:ppap2d
uniprot id: A0A3B4E8A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:atic
gene id: 42514:atic
uniprot id: A0A3B4DCA5
names: Similarity
messages: Belongs to the PurH family.

42514:cog1
gene id: 42514:cog1
uniprot id: A0A3B4C6Z3
uniprot id: A0A3B4DWA8
names: Similarity
messages: Belongs to the COG1 family.

42514:LOC108435109
gene id: 42514:LOC108435109
uniprot id: A0A3B4CTJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:scd
gene id: 42514:scd
uniprot id: A0A3B4CMU1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

42514:gtpbp1
gene id: 42514:gtpbp1
uniprot id: A0A3B4DZA2
uniprot id: A0A3B4E229
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

42514:wars2
gene id: 42514:wars2
uniprot id: A0A3B4DRW7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:LOC108441166
gene id: 42514:LOC108441166
uniprot id: A0A3B4CZV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

42514:snx13
gene id: 42514:snx13
uniprot id: A0A3B4DST2
names: Similarity
messages: Belongs to the sorting nexin family.

42514:ppp2r2d
gene id: 42514:ppp2r2d
uniprot id: A0A3B4DS45
uniprot id: A0A3B4DUP6
uniprot id: A0A3B4DVV9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

42514:svilc
gene id: 42514:svilc
uniprot id: A0A3B4BQZ2
names: Similarity
messages: Belongs to the villin/gelsolin family.

42514:bicd1a
gene id: 42514:bicd1a
uniprot id: A0A3B4CT07
uniprot id: A0A3B4CT48
names: Similarity
messages: Belongs to the BicD family.

42514:ptger4a
gene id: 42514:ptger4a
uniprot id: A0A3B4BRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

42514:si:ch211-195b13.1
gene id: 42514:si:ch211-195b13.1
uniprot id: A0A3B4E0E4
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

42514:celf1
gene id: 42514:celf1
uniprot id: A0A3B4C710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

42514:LOC108410891
gene id: 42514:LOC108410891
uniprot id: A0A3B4EEH0
names: Cofactor
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.

42514:lmod3
gene id: 42514:lmod3
uniprot id: A0A3B4CST8
names: Subcellular Location Annotation
messages: cytoskeleton

42514:dhx8
gene id: 42514:dhx8
uniprot id: A0A3B4BTP9
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108413284
gene id: 42514:LOC108413284
uniprot id: A0A3B4EPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:ptena
gene id: 42514:ptena
uniprot id: A0A3B4DWI4
uniprot id: A0A3B4DXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

42514:hint1
gene id: 42514:hint1
uniprot id: A0A3B4EAF2
names: Similarity
messages: Belongs to the HINT family.

42514:gngt2a
gene id: 42514:gngt2a
uniprot id: A0A3B4CJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

42514:elf3
gene id: 42514:elf3
uniprot id: A0A3B4BZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

42514:pax6a
gene id: 42514:pax6a
uniprot id: A0A3B4CZC8
uniprot id: A0A3B4D3J5
uniprot id: A0A3B4EF18
uniprot id: A0A3B4EF95
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:bves
gene id: 42514:bves
uniprot id: A0A3B4E373
names: Similarity
messages: Belongs to the popeye family.

42514:glula
gene id: 42514:glula
uniprot id: A0A3B4ED78
names: Similarity
messages: Belongs to the glutamine synthetase family.

42514:LOC108434905
gene id: 42514:LOC108434905
uniprot id: A0A3B4ERC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

42514:marchf4
gene id: 42514:marchf4
uniprot id: A0A3B4E130
names: Subcellular Location Annotation
messages: Membrane

42514:tbpl2
gene id: 42514:tbpl2
uniprot id: A0A3B4BT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

42514:zgc:112294
gene id: 42514:zgc:112294
uniprot id: A0A3B4DDC9
names: Subcellular Location Annotation
messages: Membrane

42514:guk1a
gene id: 42514:guk1a
uniprot id: A0A3B4DEC0
uniprot id: A0A3B4DI23
names: Similarity
messages: Belongs to the guanylate kinase family.

42514:pde10a
gene id: 42514:pde10a
uniprot id: A0A3B4D926
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:lsr
gene id: 42514:lsr
uniprot id: A0A3B4BUH7
uniprot id: A0A3B4BUS6
uniprot id: A0A3B4DML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

42514:pnpla6
gene id: 42514:pnpla6
uniprot id: A0A3B4EEW1
uniprot id: A0A3B4EGD4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:tor4aa
gene id: 42514:tor4aa
uniprot id: A0A3B4DW43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Membrane

42514:atp5mc3b
gene id: 42514:atp5mc3b
uniprot id: A0A3B4C4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

42514:LOC108430182
gene id: 42514:LOC108430182
uniprot id: A0A3B4DTQ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

42514:man2a1
gene id: 42514:man2a1
uniprot id: A0A3B4DGZ6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

42514:zgc:165520
gene id: 42514:zgc:165520
uniprot id: A0A3B4CC38
names: Similarity
messages: Belongs to the syntaxin family.

42514:cnksr3
gene id: 42514:cnksr3
uniprot id: A0A3B4DM95
names: Similarity
messages: Belongs to the CNKSR family.

42514:ppp1r14c
gene id: 42514:ppp1r14c
uniprot id: A0A3B4CYT6
names: Similarity
messages: Belongs to the PP1 inhibitor family.

42514:hip1
gene id: 42514:hip1
uniprot id: A0A3B4BT66
names: Similarity
messages: Belongs to the SLA2 family.

42514:slc25a25b
gene id: 42514:slc25a25b
uniprot id: A0A3B4DUM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:ccbe1
gene id: 42514:ccbe1
uniprot id: A0A3B4EEX6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:hm13
gene id: 42514:hm13
uniprot id: A0A3B4DFR7
uniprot id: A0A3B4DG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

42514:kbtbd8
gene id: 42514:kbtbd8
uniprot id: A0A3B4E119
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

42514:atl2
gene id: 42514:atl2
uniprot id: A0A3B4EQ30
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

42514:igf2bp2b
gene id: 42514:igf2bp2b
uniprot id: A0A3B4DR65
names: Similarity
messages: Belongs to the RRM IMP/VICKZ family.

42514:LOC108436548
gene id: 42514:LOC108436548
uniprot id: A0A3B4BT13
uniprot id: A0A3B4DJX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

42514:mbpa
gene id: 42514:mbpa
uniprot id: A0A3B4CL54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

42514:sufu
gene id: 42514:sufu
uniprot id: A0A3B4CC60
uniprot id: A0A3B4CF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

42514:lipia
gene id: 42514:lipia
uniprot id: A0A3B4DW57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

42514:LOC108430038
gene id: 42514:LOC108430038
uniprot id: A0A3B4EE75
uniprot id: A0A3B4EFQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

42514:scn12aa
gene id: 42514:scn12aa
uniprot id: A0A3B4D3E4
uniprot id: A0A3B4EGX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

42514:mapkapk2a
gene id: 42514:mapkapk2a
uniprot id: A0A3B4DR91
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:ctsd
gene id: 42514:ctsd
uniprot id: A0A3B4CLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Lysosome

42514:ern2
gene id: 42514:ern2
uniprot id: A0A3B4CBQ6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:rln1
gene id: 42514:rln1
uniprot id: A0A3B4CKB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

42514:pdzk1ip1
gene id: 42514:pdzk1ip1
uniprot id: A0A3B4ECZ5
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108434146
gene id: 42514:LOC108434146
uniprot id: A0A3B4DVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:nmnat2
gene id: 42514:nmnat2
uniprot id: A0A3B4DRR5
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

42514:slc25a24
gene id: 42514:slc25a24
uniprot id: A0A3B4DEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:pabir2
gene id: 42514:pabir2
uniprot id: A0A3B4CS60
names: Similarity
messages: Belongs to the FAM122 family.

42514:cdkn2aipnl
gene id: 42514:cdkn2aipnl
uniprot id: A0A3B4CB72
names: Similarity
messages: Belongs to the CARF family.

42514:LOC108429215
gene id: 42514:LOC108429215
uniprot id: A0A3B4DVM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:xpr1b
gene id: 42514:xpr1b
uniprot id: A0A3B4D5R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

42514:rgs3a
gene id: 42514:rgs3a
uniprot id: A0A3B4EK99
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108426626
gene id: 42514:LOC108426626
uniprot id: A0A3B4CVV3
names: Similarity
messages: Belongs to the PHYHIP family.

42514:gnpda1
gene id: 42514:gnpda1
uniprot id: A0A3B4BX56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

42514:hhat
gene id: 42514:hhat
uniprot id: A0A3B4C493
names: Subcellular Location Annotation
messages: Membrane

42514:st14a
gene id: 42514:st14a
uniprot id: A0A3B4C7S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Degrades extracellular matrix.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:tradd
gene id: 42514:tradd
uniprot id: A0A3B4BTQ3
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

42514:ltn1
gene id: 42514:ltn1
uniprot id: A0A3B4DP29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

42514:farsa
gene id: 42514:farsa
uniprot id: A0A3B4BSZ4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

42514:hat1
gene id: 42514:hat1
uniprot id: A0A3B4CSB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

42514:traf4b
gene id: 42514:traf4b
uniprot id: A0A3B4DZP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

42514:pknox2
gene id: 42514:pknox2
uniprot id: A0A3B4E7G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

42514:pofut1
gene id: 42514:pofut1
uniprot id: A0A3B4DNF2
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

42514:LOC108429845
gene id: 42514:LOC108429845
uniprot id: A0A3B4BZH8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:adamts15a
gene id: 42514:adamts15a
uniprot id: A0A3B4C565
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:coro1a
gene id: 42514:coro1a
uniprot id: A0A3B4E8L6
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:slc27a2a
gene id: 42514:slc27a2a
uniprot id: A0A3B4DQT7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:snx21
gene id: 42514:snx21
uniprot id: A0A3B4BR01
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

42514:derl1
gene id: 42514:derl1
uniprot id: A0A3B4DAF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

42514:taar1b
gene id: 42514:taar1b
uniprot id: A0A3B4CXS2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:copb1
gene id: 42514:copb1
uniprot id: A0A3B4DZ52
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

42514:arl5a
gene id: 42514:arl5a
uniprot id: A0A3B4CNF7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

42514:s100b
gene id: 42514:s100b
uniprot id: A0A3B4BQ75
names: Subcellular Location Annotation
messages: Secreted

42514:adamts13
gene id: 42514:adamts13
uniprot id: A0A3B4CIJ5
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:LOC108434182
gene id: 42514:LOC108434182
uniprot id: A0A3B4C101
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

42514:edil3a
gene id: 42514:edil3a
uniprot id: A0A3B4C762
uniprot id: A0A3B4DWE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108429307
gene id: 42514:LOC108429307
uniprot id: A0A3B4BNU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

42514:eif1axb
gene id: 42514:eif1axb
uniprot id: A0A3B4CWP6
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

42514:bmpr2b
gene id: 42514:bmpr2b
uniprot id: A0A3B4EGU9
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

42514:lpar3
gene id: 42514:lpar3
uniprot id: A0A3B4DYE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:lmna
gene id: 42514:lmna
uniprot id: A0A3B4C3G3
names: Similarity
messages: Belongs to the intermediate filament family.

42514:arhgef3
gene id: 42514:arhgef3
uniprot id: A0A3B4DEZ5
uniprot id: A0A3B4DG39
uniprot id: A0A3B4EQV3
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

42514:LOC108439235
gene id: 42514:LOC108439235
uniprot id: A0A3B4C1Q8
names: Subcellular Location Annotation
messages: Membrane

42514:yme1l1a
gene id: 42514:yme1l1a
uniprot id: A0A3B4D4Q4
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

42514:hnrnpul1
gene id: 42514:hnrnpul1
uniprot id: A0A3B4ES43
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108431381
gene id: 42514:LOC108431381
uniprot id: A0A3B4C3B6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

42514:ccdc181
gene id: 42514:ccdc181
uniprot id: A0A3B4C1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

42514:cplx2l
gene id: 42514:cplx2l
uniprot id: A0A3B4CV68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

42514:unm sa1261
gene id: 42514:unm_sa1261
uniprot id: A0A3B4D108
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

42514:adra1ab
gene id: 42514:adra1ab
uniprot id: A0A3B4D2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:hmgn6
gene id: 42514:hmgn6
uniprot id: A0A3B4C4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

42514:ubac2
gene id: 42514:ubac2
uniprot id: A0A3B4DSP9
names: Subcellular Location Annotation
messages: Membrane

42514:top1l
gene id: 42514:top1l
uniprot id: A0A3B4BX75
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

42514:srfb
gene id: 42514:srfb
uniprot id: A0A3B4DV31
names: Subcellular Location Annotation
messages: Nucleus

42514:viml
gene id: 42514:viml
uniprot id: A0A3B4DW41
names: Function
names: Similarity
messages: Belongs to the intermediate filament family.
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

42514:alg8
gene id: 42514:alg8
uniprot id: A0A3B4CED4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:limk1a
gene id: 42514:limk1a
uniprot id: A0A3B4DGN6
uniprot id: A0A3B4DGP1
uniprot id: A0A3B4DKY8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

42514:strn4
gene id: 42514:strn4
uniprot id: A0A3B4D0L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

42514:tnmd
gene id: 42514:tnmd
uniprot id: A0A3B4CMQ9
names: Similarity
messages: Belongs to the chondromodulin-1 family.

42514:c6
gene id: 42514:c6
uniprot id: A0A3B4CH09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:ppih
gene id: 42514:ppih
uniprot id: A0A3B4ELE8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:fktn
gene id: 42514:fktn
uniprot id: A0A3B4DIL7
names: Similarity
messages: Belongs to the LicD transferase family.

42514:LOC108410696
gene id: 42514:LOC108410696
uniprot id: A0A3B4CID2
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

42514:clcn4
gene id: 42514:clcn4
uniprot id: A0A3B4BPE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

42514:tcf7l1a
gene id: 42514:tcf7l1a
uniprot id: A0A3B4CIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

42514:pgap6
gene id: 42514:pgap6
uniprot id: A0A3B4DUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

42514:tmem263
gene id: 42514:tmem263
uniprot id: A0A3B4E540
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

42514:LOC108410568
gene id: 42514:LOC108410568
uniprot id: A0A3B4CQP3
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

42514:zgc:158260
gene id: 42514:zgc:158260
uniprot id: A0A3B4ERA1
names: Similarity
messages: Belongs to the FAM47 family.

42514:LOC108435834
gene id: 42514:LOC108435834
uniprot id: A0A3B4CAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:hs3st1l1
gene id: 42514:hs3st1l1
uniprot id: A0A3B4DTZ4
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

42514:coq2
gene id: 42514:coq2
uniprot id: A0A3B4DWW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

42514:LOC108415267
gene id: 42514:LOC108415267
uniprot id: A0A3B4DHQ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:actn3a
gene id: 42514:actn3a
uniprot id: A0A3B4DRT4
names: Similarity
messages: Belongs to the alpha-actinin family.

42514:LOC108429263
gene id: 42514:LOC108429263
uniprot id: A0A3B4C0W4
names: Similarity
messages: Belongs to the phospholipase D family.

42514:LOC108429410
gene id: 42514:LOC108429410
uniprot id: A0A3B4EHY7
uniprot id: A0A3B4ELR6
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

42514:dmac2l
gene id: 42514:dmac2l
uniprot id: A0A3B4C9H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

42514:med17
gene id: 42514:med17
uniprot id: A0A3B4E931
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

42514:camk2b1
gene id: 42514:camk2b1
uniprot id: A0A3B4BYU0
uniprot id: A0A3B4BZB1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

42514:LOC108413774
gene id: 42514:LOC108413774
uniprot id: A0A3B4BWI3
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108426419
gene id: 42514:LOC108426419
uniprot id: A0A3B4DGU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:midn
gene id: 42514:midn
uniprot id: A0A3B4CPQ5
names: Subcellular Location Annotation
messages: Nucleus

42514:atf7a
gene id: 42514:atf7a
uniprot id: A0A3B4EIS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

42514:gal3st3
gene id: 42514:gal3st3
uniprot id: A0A3B4DQG5
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

42514:tmem41b
gene id: 42514:tmem41b
uniprot id: A0A3B4END4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

42514:psmb13a
gene id: 42514:psmb13a
uniprot id: A0A3B4C047
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides.

42514:uchl1
gene id: 42514:uchl1
uniprot id: A0A3B4BRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:fgf6a
gene id: 42514:fgf6a
uniprot id: A0A3B4DJ63
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

42514:tnpo1
gene id: 42514:tnpo1
uniprot id: A0A3B4ECV1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:slc25a3a
gene id: 42514:slc25a3a
uniprot id: A0A3B4E336
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

42514:zdhhc12b
gene id: 42514:zdhhc12b
uniprot id: A0A3B4C863
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

42514:rad9a
gene id: 42514:rad9a
uniprot id: A0A3B4EJ68
names: Similarity
messages: Belongs to the rad9 family.

42514:ephb3a
gene id: 42514:ephb3a
uniprot id: A0A3B4CG33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:LOC108411774
gene id: 42514:LOC108411774
uniprot id: A0A3B4E416
names: Similarity
messages: Belongs to the serpin family.

42514:atp6ap1la
gene id: 42514:atp6ap1la
uniprot id: A0A3B4EN85
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

42514:ca14
gene id: 42514:ca14
uniprot id: A0A3B4C3M3
uniprot id: A0A3B4DP98
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

42514:pnp5a
gene id: 42514:pnp5a
uniprot id: A0A3B4DPN9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

42514:kcnab2a
gene id: 42514:kcnab2a
uniprot id: A0A3B4D874
uniprot id: A0A3B4DAT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: axon
messages: cytoskeleton
messages: synaptosome

42514:LOC108414972
gene id: 42514:LOC108414972
uniprot id: A0A3B4C0K7
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

42514:stx11a
gene id: 42514:stx11a
uniprot id: A0A3B4BM59
names: Similarity
messages: Belongs to the syntaxin family.

42514:dusp3b
gene id: 42514:dusp3b
uniprot id: A0A3B4C5A1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of AMPK and MAPK1/2 signaling pathways.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

42514:igfbp2a
gene id: 42514:igfbp2a
uniprot id: A0A3B4BT42
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:avd
gene id: 42514:avd
uniprot id: A0A3B4CWM3
names: Similarity
messages: Belongs to the avidin/streptavidin family.

42514:LOC108423895
gene id: 42514:LOC108423895
uniprot id: A0A3B4CDX4
uniprot id: A0A3B4CI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:LOC108431779
gene id: 42514:LOC108431779
uniprot id: A0A3B4CQ19
names: Similarity
messages: Belongs to the NipSnap family.

42514:slc35a3b
gene id: 42514:slc35a3b
uniprot id: A0A3B4E3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

42514:khdc4
gene id: 42514:khdc4
uniprot id: A0A3B4CZK9
names: Similarity
messages: Belongs to the KHDC4 family.

42514:grin2cb
gene id: 42514:grin2cb
uniprot id: A0A3B4C9I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

42514:ncoa3
gene id: 42514:ncoa3
uniprot id: A0A3B4DRQ4
names: Similarity
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.

42514:nat9
gene id: 42514:nat9
uniprot id: A0A3B4BW76
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

42514:LOC108427785
gene id: 42514:LOC108427785
uniprot id: A0A3B4CW40
uniprot id: A0A3B4CZZ1
uniprot id: A0A3B4ED99
uniprot id: A0A3B4EEG4
uniprot id: A0A3B4EEK0
names: Similarity
messages: Belongs to the BRAG family.

42514:drd4b
gene id: 42514:drd4b
uniprot id: A0A3B4CZG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:cartl
gene id: 42514:cartl
uniprot id: A0A3B4CYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

42514:lztfl1
gene id: 42514:lztfl1
uniprot id: A0A3B4E1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

42514:gja10b
gene id: 42514:gja10b
uniprot id: A0A3B4C538
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:lamb2l
gene id: 42514:lamb2l
uniprot id: A0A3B4D2F6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

42514:chmp2ba
gene id: 42514:chmp2ba
uniprot id: A0A3B4CKT3
names: Similarity
messages: Belongs to the SNF7 family.

42514:gatad1
gene id: 42514:gatad1
uniprot id: A0A3B4D886
names: Subcellular Location Annotation
messages: Nucleus

42514:dyrk1ab
gene id: 42514:dyrk1ab
uniprot id: A0A3B4C838
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:lmx1al
gene id: 42514:lmx1al
uniprot id: A0A3B4CFN8
names: Subcellular Location Annotation
messages: Nucleus

42514:ca7
gene id: 42514:ca7
uniprot id: A0A3B4BT95
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

42514:kdm3b
gene id: 42514:kdm3b
uniprot id: A0A3B4EHX1
names: Subcellular Location Annotation
messages: Nucleus

42514:psma3
gene id: 42514:psma3
uniprot id: A0A3B4DGN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

42514:LOC108441623
gene id: 42514:LOC108441623
uniprot id: A0A3B4DB82
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

42514:stmn2a
gene id: 42514:stmn2a
uniprot id: A0A3B4BYW2
names: Similarity
messages: Belongs to the stathmin family.

42514:LOC108428625
gene id: 42514:LOC108428625
uniprot id: A0A3B4BXN2
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

42514:LOC108443299
gene id: 42514:LOC108443299
uniprot id: A0A3B4DHJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

42514:stoml3b
gene id: 42514:stoml3b
uniprot id: A0A3B4D7Z2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

42514:LOC108426735
gene id: 42514:LOC108426735
uniprot id: A0A3B4E3W8
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108434966
gene id: 42514:LOC108434966
uniprot id: A0A3B4DE12
names: Similarity
messages: Belongs to the dysbindin family.

42514:LOC108434136
gene id: 42514:LOC108434136
uniprot id: A0A3B4DT55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:stx12l
gene id: 42514:stx12l
uniprot id: A0A3B4E1W7
names: Similarity
messages: Belongs to the syntaxin family.

42514:zgc:63587
gene id: 42514:zgc:63587
uniprot id: A0A3B4DJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

42514:slc25a42
gene id: 42514:slc25a42
uniprot id: A0A3B4D6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:polr2h
gene id: 42514:polr2h
uniprot id: A0A3B4C0J2
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

42514:cog2
gene id: 42514:cog2
uniprot id: A0A3B4CEW1
names: Similarity
messages: Belongs to the COG2 family.

42514:nkain1
gene id: 42514:nkain1
uniprot id: A0A3B4D6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

42514:LOC108429863
gene id: 42514:LOC108429863
uniprot id: A0A3B4BUX5
uniprot id: A0A3B4DPI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

42514:LOC108410710
gene id: 42514:LOC108410710
uniprot id: A0A3B4E0M4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

42514:gdnfa
gene id: 42514:gdnfa
uniprot id: A0A3B4EB85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Homodimer; disulfide-linked.
messages: Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
messages: Secreted

42514:il1rapl1a
gene id: 42514:il1rapl1a
uniprot id: A0A3B4DG48
uniprot id: A0A3B4DKB0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

42514:mipepa
gene id: 42514:mipepa
uniprot id: A0A3B4DNI6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

42514:nsun4
gene id: 42514:nsun4
uniprot id: A0A3B4BTA9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

42514:aebp1
gene id: 42514:aebp1
uniprot id: A0A3B4D6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

42514:adam19b
gene id: 42514:adam19b
uniprot id: A0A3B4EET4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108442284
gene id: 42514:LOC108442284
uniprot id: A0A3B4EC81
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

42514:trappc6bl
gene id: 42514:trappc6bl
uniprot id: A0A3B4CZT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

42514:per2
gene id: 42514:per2
uniprot id: A0A3B4DD80
uniprot id: A0A3B4ELP9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:shroom2a
gene id: 42514:shroom2a
uniprot id: A0A3B4D3T2
uniprot id: A0A3B4EI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

42514:hapln3
gene id: 42514:hapln3
uniprot id: A0A3B4EAC4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:f7l
gene id: 42514:f7l
uniprot id: A0A3B4DT30
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:naa25
gene id: 42514:naa25
uniprot id: A0A3B4C6H8
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

42514:slc10a4
gene id: 42514:slc10a4
uniprot id: A0A3B4BZF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

42514:rangrf
gene id: 42514:rangrf
uniprot id: A0A3B4CNA3
names: Similarity
messages: Belongs to the MOG1 family.

42514:mzt2b
gene id: 42514:mzt2b
uniprot id: A0A3B4E0C6
uniprot id: A0A3B4E4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: centrosome
messages: spindle

42514:cxxc4
gene id: 42514:cxxc4
uniprot id: A0A3B4C5E0
names: Subcellular Location Annotation
messages: Cytoplasm

42514:fbl
gene id: 42514:fbl
uniprot id: A0A3B4CWJ8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

42514:gpn2
gene id: 42514:gpn2
uniprot id: A0A3B4DC12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

42514:foxa1
gene id: 42514:foxa1
uniprot id: A0A3B4BQ81
names: Subcellular Location Annotation
messages: Nucleus

42514:ing3
gene id: 42514:ing3
uniprot id: A0A3B4DNI0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

42514:bcl2b
gene id: 42514:bcl2b
uniprot id: A0A3B4CHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

42514:sdc2
gene id: 42514:sdc2
uniprot id: A0A3B4D357
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

42514:cdc37l1
gene id: 42514:cdc37l1
uniprot id: A0A3B4E471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

42514:LOC108424956
gene id: 42514:LOC108424956
uniprot id: A0A3B4CX65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actinoporin family. Sea anemone subfamily.
messages: Cell membrane
messages: Membrane
messages: Nematocyst
messages: Target cell membrane

42514:p4ha1b
gene id: 42514:p4ha1b
uniprot id: A0A3B4CXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

42514:arl3a
gene id: 42514:arl3a
uniprot id: A0A3B4CFE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

42514:camk1db
gene id: 42514:camk1db
uniprot id: A0A3B4BQ31
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:pms2
gene id: 42514:pms2
uniprot id: A0A3B4BWZ1
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

42514:cdc26
gene id: 42514:cdc26
uniprot id: A0A3B4BS85
names: Similarity
messages: Belongs to the CDC26 family.

42514:sqlea
gene id: 42514:sqlea
uniprot id: A0A3B4E1T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

42514:atp13a1
gene id: 42514:atp13a1
uniprot id: A0A3B4CFU9
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

42514:aqp8a.1
gene id: 42514:aqp8a.1
uniprot id: A0A3B4BY34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:mpi
gene id: 42514:mpi
uniprot id: A0A3B4EHH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

42514:LOC108440227
gene id: 42514:LOC108440227
uniprot id: A0A3B4DRH1
names: Similarity
messages: Belongs to the globin family.

42514:nr4a2a
gene id: 42514:nr4a2a
uniprot id: A0A3B4CHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:prom1a
gene id: 42514:prom1a
uniprot id: A0A3B4D9L4
uniprot id: A0A3B4DAR3
uniprot id: A0A3B4EKA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

42514:adamts1
gene id: 42514:adamts1
uniprot id: A0A3B4BZ83
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

42514:ppa1b
gene id: 42514:ppa1b
uniprot id: A0A3B4BRE2
names: Similarity
messages: Belongs to the PPase family.

42514:arcn1b
gene id: 42514:arcn1b
uniprot id: A0A3B4BUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

42514:smu1b
gene id: 42514:smu1b
uniprot id: A0A3B4CJP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

42514:nfu1
gene id: 42514:nfu1
uniprot id: A0A3B4CUF9
names: Similarity
messages: Belongs to the NifU family.

42514:p2ry8
gene id: 42514:p2ry8
uniprot id: A0A3B4CT19
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:sema7a
gene id: 42514:sema7a
uniprot id: A0A3B4C7T4
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:prr15lb
gene id: 42514:prr15lb
uniprot id: A0A3B4DH72
names: Similarity
messages: Belongs to the PRR15 family.

42514:nudt12
gene id: 42514:nudt12
uniprot id: A0A3B4BWR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

42514:gsta.1
gene id: 42514:gsta.1
uniprot id: A0A3B4D6V5
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

42514:mrpl14
gene id: 42514:mrpl14
uniprot id: A0A3B4E5A1
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

42514:apoc1
gene id: 42514:apoc1
uniprot id: A0A3B4D990
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Secreted

42514:zgc:92275
gene id: 42514:zgc:92275
uniprot id: A0A3B4DDC4
names: Similarity
messages: Belongs to the cholesterol 7-desaturase family.

42514:LOC108431612
gene id: 42514:LOC108431612
uniprot id: A0A3B4ELJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

42514:LOC108412307
gene id: 42514:LOC108412307
uniprot id: A0A3B4DYY2
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6c family.

42514:bpnt2
gene id: 42514:bpnt2
uniprot id: A0A3B4DDA4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

42514:sept12
gene id: 42514:sept12
uniprot id: A0A3B4D8E8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

42514:LOC108440018
gene id: 42514:LOC108440018
uniprot id: A0A3B4CX11
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:itih5
gene id: 42514:itih5
uniprot id: A0A3B4DLL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

42514:vill
gene id: 42514:vill
uniprot id: A0A3B4CU03
names: Similarity
messages: Belongs to the villin/gelsolin family.

42514:sv2ca
gene id: 42514:sv2ca
uniprot id: A0A3B4DUA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

42514:creb5a
gene id: 42514:creb5a
uniprot id: A0A3B4DK28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
messages: Binds to the cAMP response element and activates transcription.
messages: Nucleus

42514:sars1
gene id: 42514:sars1
uniprot id: A0A3B4EEW0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

42514:cpne8
gene id: 42514:cpne8
uniprot id: A0A3B4BLC7
names: Similarity
messages: Belongs to the copine family.

42514:fam193a
gene id: 42514:fam193a
uniprot id: A0A3B4CP52
names: Similarity
messages: Belongs to the FAM193 family.

42514:mov10a
gene id: 42514:mov10a
uniprot id: A0A3B4DPV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

42514:LOC108434183
gene id: 42514:LOC108434183
uniprot id: A0A3B4BY06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

42514:tgm5l
gene id: 42514:tgm5l
uniprot id: A0A3B4ERE7
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

42514:bsg
gene id: 42514:bsg
uniprot id: A0A3B4CRH5
uniprot id: A0A3B4CRI5
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane

42514:vps33b
gene id: 42514:vps33b
uniprot id: A0A3B4CZG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

42514:acsl3b
gene id: 42514:acsl3b
uniprot id: A0A3B4DCF7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:si:ch73-60h1.1
gene id: 42514:si:ch73-60h1.1
uniprot id: A0A3B4D3L3
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:hoxb8a
gene id: 42514:hoxb8a
uniprot id: A0A3B4DYF0
names: Subcellular Location Annotation
messages: Nucleus

42514:kmt5c
gene id: 42514:kmt5c
uniprot id: A0A3B4CT74
names: Subcellular Location Annotation
messages: Nucleus

42514:mcm6
gene id: 42514:mcm6
uniprot id: A0A3B4CX69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

42514:rap2c
gene id: 42514:rap2c
uniprot id: A0A3B4DJT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

42514:gba2
gene id: 42514:gba2
uniprot id: A0A3B4CRH9
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

42514:LOC108427389
gene id: 42514:LOC108427389
uniprot id: A0A3B4DZU0
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:LOC108442742
gene id: 42514:LOC108442742
uniprot id: A0A3B4DFL7
names: Subcellular Location Annotation
messages: Membrane

42514:tnfrsf21
gene id: 42514:tnfrsf21
uniprot id: A0A3B4CIQ1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:adam17b
gene id: 42514:adam17b
uniprot id: A0A3B4D252
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:rab38c
gene id: 42514:rab38c
uniprot id: A0A3B4CCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

42514:dlx6a
gene id: 42514:dlx6a
uniprot id: A0A3B4DEH0
names: Subcellular Location Annotation
messages: Nucleus

42514:acvr1ba
gene id: 42514:acvr1ba
uniprot id: A0A3B4EDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

42514:LOC108427205
gene id: 42514:LOC108427205
uniprot id: A0A3B4CVZ0
names: Similarity
messages: Belongs to the peptidase C1 family.

42514:zgc:153039
gene id: 42514:zgc:153039
uniprot id: A0A3B4CZN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:pard3aa
gene id: 42514:pard3aa
uniprot id: A0A3B4BRI4
uniprot id: A0A3B4DG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

42514:m17
gene id: 42514:m17
uniprot id: A0A3B4DKK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

42514:prph2b
gene id: 42514:prph2b
uniprot id: A0A3B4C5I1
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

42514:cadm3
gene id: 42514:cadm3
uniprot id: A0A3B4CXB5
uniprot id: A0A3B4CZH9
uniprot id: A0A3B4ECA9
names: Similarity
messages: Belongs to the nectin family.

42514:LOC108411980
gene id: 42514:LOC108411980
uniprot id: A0A3B4DRE3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:stk38a
gene id: 42514:stk38a
uniprot id: A0A3B4CZB3
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:psme2
gene id: 42514:psme2
uniprot id: A0A3B4C153
names: Similarity
messages: Belongs to the PA28 family.

42514:dhrs13l1
gene id: 42514:dhrs13l1
uniprot id: A0A3B4EF25
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:carnmt1
gene id: 42514:carnmt1
uniprot id: A0A3B4BVY3
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

42514:LOC108434502
gene id: 42514:LOC108434502
uniprot id: A0A3B4EGB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

42514:LOC108439629
gene id: 42514:LOC108439629
uniprot id: A0A3B4DY86
names: Similarity
messages: Belongs to the GADD45 family.

42514:klhl40a
gene id: 42514:klhl40a
uniprot id: A0A3B4EM04
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

42514:arg2
gene id: 42514:arg2
uniprot id: A0A3B4DX88
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

42514:c12h3orf70
gene id: 42514:c12h3orf70
uniprot id: A0A3B4DS34
names: Similarity
messages: Belongs to the UPF0524 family.

42514:ess2
gene id: 42514:ess2
uniprot id: A0A3B4DZ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

42514:trpc7a
gene id: 42514:trpc7a
uniprot id: A0A3B4CUC1
names: Subcellular Location Annotation
messages: Membrane

42514:paqr7a
gene id: 42514:paqr7a
uniprot id: A0A3B4EJ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:ap1g2
gene id: 42514:ap1g2
uniprot id: A0A3B4CWK1
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

42514:tmcc1b
gene id: 42514:tmcc1b
uniprot id: A0A3B4C4W2
names: Similarity
messages: Belongs to the TEX28 family.

42514:snx5
gene id: 42514:snx5
uniprot id: A0A3B4CKX0
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

42514:serinc4
gene id: 42514:serinc4
uniprot id: A0A3B4CXI6
uniprot id: A0A3B4EAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

42514:LOC108442385
gene id: 42514:LOC108442385
uniprot id: A0A3B4ERU2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

42514:LOC108439293
gene id: 42514:LOC108439293
uniprot id: A0A3B4DFE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

42514:atp6v1ab
gene id: 42514:atp6v1ab
uniprot id: A0A3B4EA49
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

42514:tph1b
gene id: 42514:tph1b
uniprot id: A0A3B4E155
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

42514:LOC108429918
gene id: 42514:LOC108429918
uniprot id: A0A3B4EH91
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

42514:lmod2a
gene id: 42514:lmod2a
uniprot id: A0A3B4CGX6
names: Subcellular Location Annotation
messages: cytoskeleton

42514:LOC108441491
gene id: 42514:LOC108441491
uniprot id: A0A3B4DMU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:LOC108429927
gene id: 42514:LOC108429927
uniprot id: A0A3B4EEQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

42514:noc3l
gene id: 42514:noc3l
uniprot id: A0A3B4DV80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

42514:med28
gene id: 42514:med28
uniprot id: A0A3B4C3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

42514:zmynd10
gene id: 42514:zmynd10
uniprot id: A0A3B4CCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

42514:tmem200b
gene id: 42514:tmem200b
uniprot id: A0A3B4EGS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

42514:immp1l
gene id: 42514:immp1l
uniprot id: A0A3B4BPT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

42514:LOC108413091
gene id: 42514:LOC108413091
uniprot id: A0A3B4BY84
names: Similarity
messages: Belongs to the MHC class I family.

42514:LOC108440213
gene id: 42514:LOC108440213
uniprot id: A0A3B4DWK7
names: Similarity
messages: Belongs to the globin family.

42514:tnk2b
gene id: 42514:tnk2b
uniprot id: A0A3B4C9P5
uniprot id: A0A3B4DVI8
uniprot id: A0A3B4DVP3
uniprot id: A0A3B4DWY1
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

42514:ehd2b
gene id: 42514:ehd2b
uniprot id: A0A3B4D651
uniprot id: A0A3B4EI34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

42514:man2c1
gene id: 42514:man2c1
uniprot id: A0A3B4C891
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

42514:vps16
gene id: 42514:vps16
uniprot id: A0A3B4EBZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

42514:lim2.5
gene id: 42514:lim2.5
uniprot id: A0A3B4EE94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:cdk8
gene id: 42514:cdk8
uniprot id: A0A3B4D2Q5
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:manea
gene id: 42514:manea
uniprot id: A0A3B4DMA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

42514:gkap1
gene id: 42514:gkap1
uniprot id: A0A3B4E487
names: Similarity
messages: Belongs to the GKAP1 family.

42514:ehd4
gene id: 42514:ehd4
uniprot id: A0A3B4CQ04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

42514:vcla
gene id: 42514:vcla
uniprot id: A0A3B4CAH2
uniprot id: A0A3B4CCC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

42514:ing4
gene id: 42514:ing4
uniprot id: A0A3B4D099
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

42514:rnf111
gene id: 42514:rnf111
uniprot id: A0A3B4CR62
uniprot id: A0A3B4EBA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Arkadia family.
messages: PML body

42514:unc5db
gene id: 42514:unc5db
uniprot id: A0A3B4BWT2
uniprot id: A0A3B4BWV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

42514:max
gene id: 42514:max
uniprot id: A0A3B4C226
names: Similarity
messages: Belongs to the MAX family.

42514:tlr22
gene id: 42514:tlr22
uniprot id: A0A3B4CF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

42514:LOC108413237
gene id: 42514:LOC108413237
uniprot id: A0A3B4BP30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLMP family.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

42514:mmd
gene id: 42514:mmd
uniprot id: A0A3B4CP77
uniprot id: A0A3B4E3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

42514:cfap206
gene id: 42514:cfap206
uniprot id: A0A3B4E1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme
messages: cilium basal body

42514:crb1
gene id: 42514:crb1
uniprot id: A0A3B4DYE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:dguok
gene id: 42514:dguok
uniprot id: A0A3B4E947
names: Similarity
messages: Belongs to the DCK/DGK family.

42514:tmem63a
gene id: 42514:tmem63a
uniprot id: A0A3B4EEM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

42514:lyve1b
gene id: 42514:lyve1b
uniprot id: A0A3B4E6B2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:si:ch211-87j1.4
gene id: 42514:si:ch211-87j1.4
uniprot id: A0A3B4DJE9
names: Similarity
messages: Belongs to the TMEM178 family.

42514:fam171a2a
gene id: 42514:fam171a2a
uniprot id: A0A3B4CAZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

42514:tarbp2
gene id: 42514:tarbp2
uniprot id: A0A3B4C1P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.

42514:ptpn11b
gene id: 42514:ptpn11b
uniprot id: A0A3B4CS82
uniprot id: A0A3B4CU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

42514:coro6
gene id: 42514:coro6
uniprot id: A0A3B4CBR5
names: Similarity
messages: Belongs to the WD repeat coronin family.

42514:nup133
gene id: 42514:nup133
uniprot id: A0A3B4CD12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

42514:nxf1
gene id: 42514:nxf1
uniprot id: A0A3B4C1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

42514:foxj3
gene id: 42514:foxj3
uniprot id: A0A3B4BPA1
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108442487
gene id: 42514:LOC108442487
uniprot id: A0A3B4C681
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

42514:aldh5a1
gene id: 42514:aldh5a1
uniprot id: A0A3B4CZ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

42514:chga
gene id: 42514:chga
uniprot id: A0A3B4DLP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

42514:man2a2
gene id: 42514:man2a2
uniprot id: A0A3B4DCT3
uniprot id: A0A3B4EQR4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

42514:nsmce4a
gene id: 42514:nsmce4a
uniprot id: A0A3B4BTE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

42514:sebox
gene id: 42514:sebox
uniprot id: A0A3B4ELJ4
names: Subcellular Location Annotation
messages: Nucleus

42514:ap1g1
gene id: 42514:ap1g1
uniprot id: A0A3B4E0H2
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

42514:LOC108425458
gene id: 42514:LOC108425458
uniprot id: A0A3B4D4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

42514:atp2c1
gene id: 42514:atp2c1
uniprot id: A0A3B4CXM7
uniprot id: A0A3B4CY75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: trans-Golgi network membrane

42514:cbsb
gene id: 42514:cbsb
uniprot id: A0A3B4EC89
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

42514:lhfpl3
gene id: 42514:lhfpl3
uniprot id: A0A3B4BVJ2
names: Subcellular Location Annotation
messages: Membrane

42514:ndrg4
gene id: 42514:ndrg4
uniprot id: A0A3B4C045
uniprot id: A0A3B4C3G4
uniprot id: A0A3B4C452
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: cytosol

42514:churc1
gene id: 42514:churc1
uniprot id: A0A3B4C851
names: Similarity
messages: Belongs to the Churchill family.

42514:slc25a17
gene id: 42514:slc25a17
uniprot id: A0A3B4CQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:ctsc
gene id: 42514:ctsc
uniprot id: A0A3B4DA52
names: Similarity
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

42514:LOC108414696
gene id: 42514:LOC108414696
uniprot id: A0A3B4CGU2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

42514:LOC108431103
gene id: 42514:LOC108431103
uniprot id: A0A3B4D5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

42514:b4galnt3a
gene id: 42514:b4galnt3a
uniprot id: A0A3B4DDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

42514:ugp2a
gene id: 42514:ugp2a
uniprot id: A0A3B4CBE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

42514:LOC108423879
gene id: 42514:LOC108423879
uniprot id: A0A3B4CEI7
names: Subcellular Location Annotation
messages: Membrane

42514:syt14b
gene id: 42514:syt14b
uniprot id: A0A3B4EH38
names: Similarity
messages: Belongs to the synaptotagmin family.

42514:nmba
gene id: 42514:nmba
uniprot id: A0A3B4DT46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted

42514:LOC108442457
gene id: 42514:LOC108442457
uniprot id: A0A3B4C9Z5
uniprot id: A0A3B4CAU8
names: Subcellular Location Annotation
messages: Membrane

42514:prodha
gene id: 42514:prodha
uniprot id: A0A3B4CRH1
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

42514:LOC108441061
gene id: 42514:LOC108441061
uniprot id: A0A3B4D6Y2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:atf7b
gene id: 42514:atf7b
uniprot id: A0A3B4E042
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Homodimer; binds DNA as homodimer. Heterodimer; heterodimerizes with other members of ATF family and with JUN family members.
messages: Nucleus
messages: Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes. Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation. In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening.

42514:rbpms2a
gene id: 42514:rbpms2a
uniprot id: A0A3B4EL19
names: Subcellular Location Annotation
messages: Cytoplasm

42514:si:ch211-106h11.1
gene id: 42514:si:ch211-106h11.1
uniprot id: A0A3B4CAP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

42514:tada2b
gene id: 42514:tada2b
uniprot id: A0A3B4DW79
names: Subcellular Location Annotation
messages: Nucleus

42514:traf4a
gene id: 42514:traf4a
uniprot id: A0A3B4DWM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

42514:cnot6a
gene id: 42514:cnot6a
uniprot id: A0A3B4ENW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

42514:gpat4
gene id: 42514:gpat4
uniprot id: A0A3B4CLP5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

42514:gab1
gene id: 42514:gab1
uniprot id: A0A3B4D898
names: Similarity
messages: Belongs to the GAB family.

42514:rxrab
gene id: 42514:rxrab
uniprot id: A0A3B4D6S4
uniprot id: A0A3B4D8A7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

42514:lrrc8da
gene id: 42514:lrrc8da
uniprot id: A0A3B4DMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

42514:LOC108437567
gene id: 42514:LOC108437567
uniprot id: A0A3B4C834
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:htra4
gene id: 42514:htra4
uniprot id: A0A3B4BW42
names: Similarity
messages: Belongs to the peptidase S1C family.

42514:fgfr1op2
gene id: 42514:fgfr1op2
uniprot id: A0A3B4CLT1
names: Similarity
messages: Belongs to the SIKE family.

42514:bud31
gene id: 42514:bud31
uniprot id: A0A3B4D0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

42514:gpr155a
gene id: 42514:gpr155a
uniprot id: A0A3B4CU58
names: Subcellular Location Annotation
messages: Membrane

42514:glo1
gene id: 42514:glo1
uniprot id: A0A3B4CGB2
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

42514:alcamb
gene id: 42514:alcamb
uniprot id: A0A3B4C8S6
uniprot id: A0A3B4DXC2
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

42514:cfdp1
gene id: 42514:cfdp1
uniprot id: A0A3B4E414
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

42514:cryba4
gene id: 42514:cryba4
uniprot id: A0A3B4BW09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

42514:LOC108437237
gene id: 42514:LOC108437237
uniprot id: A0A3B4D7W4
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

42514:psmb11a
gene id: 42514:psmb11a
uniprot id: A0A3B4EDI2
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108411439
gene id: 42514:LOC108411439
uniprot id: A0A3B4DD92
names: Similarity
messages: Belongs to the actin family.

42514:LOC108436859
gene id: 42514:LOC108436859
uniprot id: A0A3B4E3R3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

42514:acss2
gene id: 42514:acss2
uniprot id: A0A3B4BXZ1
uniprot id: A0A3B4DN71
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:chrnd
gene id: 42514:chrnd
uniprot id: A0A3B4DTP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:pkn3
gene id: 42514:pkn3
uniprot id: A0A3B4DUV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Nucleus

42514:dennd5b
gene id: 42514:dennd5b
uniprot id: A0A3B4CK41
uniprot id: A0A3B4CK92
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:LOC108425971
gene id: 42514:LOC108425971
uniprot id: A0A3B4EQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:tspy
gene id: 42514:tspy
uniprot id: A0A3B4D1Y7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

42514:LOC108434663
gene id: 42514:LOC108434663
uniprot id: A0A3B4CKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

42514:fgfbp3
gene id: 42514:fgfbp3
uniprot id: A0A3B4DS84
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

42514:pex19
gene id: 42514:pex19
uniprot id: A0A3B4C1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxin-19 family.
messages: Interacts with a broad range of peroxisomal membrane proteins, including PEX3, PEX10, PEX11A, PEX11B, PEX12, PEX13, PEX14 and PEX16, PXMP2/PMP22, PXMP4/PMP24, SLC25A17/PMP34, ABCD1/ALDP, ABCD2/ALDRP, and ABCD3/PMP70. Also interacts with the tumor suppressor CDKN2A/p19ARF.
messages: Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.
messages: Peroxisome membrane

42514:kif3a
gene id: 42514:kif3a
uniprot id: A0A3B4DPH9
uniprot id: A0A3B4DQL1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

42514:acsm3
gene id: 42514:acsm3
uniprot id: A0A3B4ECK2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

42514:slc8a4a
gene id: 42514:slc8a4a
uniprot id: A0A3B4DTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

42514:zgc:165508
gene id: 42514:zgc:165508
uniprot id: A0A3B4BT25
names: Similarity
messages: Belongs to the FAM131 family.

42514:spon2b
gene id: 42514:spon2b
uniprot id: A0A3B4D040
names: Subcellular Location Annotation
messages: extracellular matrix

42514:dimt1l
gene id: 42514:dimt1l
uniprot id: A0A3B4CS58
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

42514:slc6a1a
gene id: 42514:slc6a1a
uniprot id: A0A3B4ECC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:grem2a
gene id: 42514:grem2a
uniprot id: A0A3B4EKJ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:hyal2a
gene id: 42514:hyal2a
uniprot id: A0A3B4C4F8
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

42514:ntn1b
gene id: 42514:ntn1b
uniprot id: A0A3B4BNG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:plpp4
gene id: 42514:plpp4
uniprot id: A0A3B4D0W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

42514:dop1a
gene id: 42514:dop1a
uniprot id: A0A3B4DV59
uniprot id: A0A3B4DY03
names: Similarity
messages: Belongs to the dopey family.

42514:LOC108414923
gene id: 42514:LOC108414923
uniprot id: A0A3B4C1H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

42514:rps17
gene id: 42514:rps17
uniprot id: A0A3B4CYB3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

42514:dipk1b
gene id: 42514:dipk1b
uniprot id: A0A3B4DCL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

42514:ap1m3
gene id: 42514:ap1m3
uniprot id: A0A3B4BX30
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

42514:chrna1
gene id: 42514:chrna1
uniprot id: A0A3B4C6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:LOC108425192
gene id: 42514:LOC108425192
uniprot id: A0A3B4CC93
uniprot id: A0A3B4CC98
uniprot id: A0A3B4CEN3
uniprot id: A0A3B4DZ71
uniprot id: A0A3B4DZ81
uniprot id: A0A3B4E0B3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:LOC108430004
gene id: 42514:LOC108430004
uniprot id: A0A3B4D1A7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:cpt1a2b
gene id: 42514:cpt1a2b
uniprot id: A0A3B4E6J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:prkab1b
gene id: 42514:prkab1b
uniprot id: A0A3B4EJH0
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

42514:stk33
gene id: 42514:stk33
uniprot id: A0A3B4CF66
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108424160
gene id: 42514:LOC108424160
uniprot id: A0A3B4D4Q6
names: Similarity
messages: Belongs to the glycosyl hydrolase 23 family.

42514:akt1
gene id: 42514:akt1
uniprot id: A0A3B4E7P7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

42514:wasb
gene id: 42514:wasb
uniprot id: A0A3B4CM13
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108444066
gene id: 42514:LOC108444066
uniprot id: A0A3B4CZZ4
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

42514:LOC108434054
gene id: 42514:LOC108434054
uniprot id: A0A3B4E2I6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:vsx2
gene id: 42514:vsx2
uniprot id: A0A3B4E9W6
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108425158
gene id: 42514:LOC108425158
uniprot id: A0A3B4BNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

42514:timm8a
gene id: 42514:timm8a
uniprot id: A0A3B4E6F7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

42514:tmem144b
gene id: 42514:tmem144b
uniprot id: A0A3B4EA33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

42514:cln3
gene id: 42514:cln3
uniprot id: A0A3B4CWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

42514:arrdc2
gene id: 42514:arrdc2
uniprot id: A0A3B4DTJ4
uniprot id: A0A3B4DX94
names: Similarity
messages: Belongs to the arrestin family.

42514:ufd1l
gene id: 42514:ufd1l
uniprot id: A0A3B4BQT3
names: Similarity
messages: Belongs to the UFD1 family.

42514:smim12
gene id: 42514:smim12
uniprot id: A0A3B4BWR9
names: Similarity
messages: Belongs to the SMIM12 family.

42514:mark2a
gene id: 42514:mark2a
uniprot id: A0A3B4C5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

42514:tspan33b
gene id: 42514:tspan33b
uniprot id: A0A3B4EAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

42514:capn5b
gene id: 42514:capn5b
uniprot id: A0A3B4CHS2
names: Similarity
messages: Belongs to the peptidase C2 family.

42514:creb5b
gene id: 42514:creb5b
uniprot id: A0A3B4BST2
uniprot id: A0A3B4DN67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.
messages: Binds to the cAMP response element and activates transcription.
messages: Nucleus

42514:thbs4a
gene id: 42514:thbs4a
uniprot id: A0A3B4DEK1
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:tle5
gene id: 42514:tle5
uniprot id: A0A3B4CMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

42514:mfsd10
gene id: 42514:mfsd10
uniprot id: A0A3B4C9V8
names: Subcellular Location Annotation
messages: Membrane

42514:cpz
gene id: 42514:cpz
uniprot id: A0A3B4DZ55
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:porcnl
gene id: 42514:porcnl
uniprot id: A0A3B4DUB3
names: Subcellular Location Annotation
messages: Membrane

42514:elovl7a
gene id: 42514:elovl7a
uniprot id: A0A3B4CBG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:snapin
gene id: 42514:snapin
uniprot id: A0A3B4E005
uniprot id: A0A3B4E2S2
names: Similarity
messages: Belongs to the SNAPIN family.

42514:prkacba
gene id: 42514:prkacba
uniprot id: A0A3B4CG40
uniprot id: A0A3B4DYY1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

42514:mrpl47
gene id: 42514:mrpl47
uniprot id: A0A3B4D902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

42514:si:ch211-261d7.3
gene id: 42514:si:ch211-261d7.3
uniprot id: A0A3B4EGY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

42514:pdlim3a
gene id: 42514:pdlim3a
uniprot id: A0A3B4D5V0
names: Subcellular Location Annotation
messages: Z line

42514:prdm4
gene id: 42514:prdm4
uniprot id: A0A3B4CHE0
names: Subcellular Location Annotation
messages: Nucleus

42514:eif2a
gene id: 42514:eif2a
uniprot id: A0A3B4EDR2
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

42514:pfdn6
gene id: 42514:pfdn6
uniprot id: A0A3B4CT91
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

42514:msrb3
gene id: 42514:msrb3
uniprot id: A0A3B4BVC8
uniprot id: A0A3B4DN13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

42514:erg28
gene id: 42514:erg28
uniprot id: A0A3B4DKE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:med29
gene id: 42514:med29
uniprot id: A0A3B4D5K5
uniprot id: A0A3B4EGU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 29 family.
messages: Nucleus

42514:tmem88b
gene id: 42514:tmem88b
uniprot id: A0A3B4C259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

42514:LOC108424720
gene id: 42514:LOC108424720
uniprot id: A0A3B4DIU6
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

42514:rplp2
gene id: 42514:rplp2
uniprot id: A0A3B4BX77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.
messages: Plays an important role in the elongation step of protein synthesis.

42514:mfsd11
gene id: 42514:mfsd11
uniprot id: A0A3B4D2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

42514:si:ch73-63e15.2
gene id: 42514:si:ch73-63e15.2
uniprot id: A0A3B4CQF6
uniprot id: A0A3B4CSH6
uniprot id: A0A3B4EAP7
names: Similarity
messages: Belongs to the SBNO family.

42514:LOC108434584
gene id: 42514:LOC108434584
uniprot id: A0A3B4E7M0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

42514:plxna4
gene id: 42514:plxna4
uniprot id: A0A3B4DLW8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:LOC108414040
gene id: 42514:LOC108414040
uniprot id: A0A3B4DH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

42514:emc4
gene id: 42514:emc4
uniprot id: A0A3B4CZC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC4 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:mfap1
gene id: 42514:mfap1
uniprot id: A0A3B4ECV3
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

42514:dbndd1
gene id: 42514:dbndd1
uniprot id: A0A3B4E3T9
names: Similarity
messages: Belongs to the dysbindin family.

42514:ptprsa
gene id: 42514:ptprsa
uniprot id: A0A3B4D0G0
uniprot id: A0A3B4D0Z0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

42514:rhot1a
gene id: 42514:rhot1a
uniprot id: A0A3B4D3Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

42514:LOC108424983
gene id: 42514:LOC108424983
uniprot id: A0A3B4CWX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:dbx2
gene id: 42514:dbx2
uniprot id: A0A3B4E4H9
names: Subcellular Location Annotation
messages: Nucleus

42514:adam12
gene id: 42514:adam12
uniprot id: A0A3B4EE65
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:asz1
gene id: 42514:asz1
uniprot id: A0A3B4C7X2
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

42514:si:dkey-239n17.4
gene id: 42514:si:dkey-239n17.4
uniprot id: A0A3B4DF00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

42514:eef2kmt
gene id: 42514:eef2kmt
uniprot id: A0A3B4D563
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EEF2KMT family.

42514:exoc1
gene id: 42514:exoc1
uniprot id: A0A3B4BTJ7
uniprot id: A0A3B4BWL2
uniprot id: A0A3B4DJX5
uniprot id: A0A3B4DMG2
names: Similarity
messages: Belongs to the SEC3 family.

42514:nfkb1
gene id: 42514:nfkb1
uniprot id: A0A3B4DR72
uniprot id: A0A3B4DV88
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:hpdb
gene id: 42514:hpdb
uniprot id: A0A3B4DWE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

42514:zfpm2a
gene id: 42514:zfpm2a
uniprot id: A0A3B4BZR4
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108440371
gene id: 42514:LOC108440371
uniprot id: A0A3B4BRA1
names: Subcellular Location Annotation
messages: Membrane

42514:atp6v0d1
gene id: 42514:atp6v0d1
uniprot id: A0A3B4C957
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

42514:tmem230a
gene id: 42514:tmem230a
uniprot id: A0A3B4ECJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

42514:cant1a
gene id: 42514:cant1a
uniprot id: A0A3B4D0N8
names: Similarity
messages: Belongs to the apyrase family.

42514:lamtor3
gene id: 42514:lamtor3
uniprot id: A0A3B4CC67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

42514:pkig
gene id: 42514:pkig
uniprot id: A0A3B4CPZ6
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

42514:mmp28
gene id: 42514:mmp28
uniprot id: A0A3B4BUT2
names: Similarity
messages: Belongs to the peptidase M10A family.

42514:dhrs13a.3
gene id: 42514:dhrs13a.3
uniprot id: A0A3B4BVB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:vps4b
gene id: 42514:vps4b
uniprot id: A0A3B4E2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

42514:htr2cl1
gene id: 42514:htr2cl1
uniprot id: A0A3B4DXF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

42514:msnb
gene id: 42514:msnb
uniprot id: A0A3B4EGA8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

42514:flvcr2a
gene id: 42514:flvcr2a
uniprot id: A0A3B4DKD2
names: Subcellular Location Annotation
messages: Membrane

42514:slc12a7b
gene id: 42514:slc12a7b
uniprot id: A0A3B4CVS1
uniprot id: A0A3B4CXW5
uniprot id: A0A3B4CZZ2
uniprot id: A0A3B4EAI9
uniprot id: A0A3B4EAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

42514:LOC108429271
gene id: 42514:LOC108429271
uniprot id: A0A3B4DQ80
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

42514:stx5a
gene id: 42514:stx5a
uniprot id: A0A3B4EL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

42514:tprkb
gene id: 42514:tprkb
uniprot id: A0A3B4EP71
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

42514:tomm20a
gene id: 42514:tomm20a
uniprot id: A0A3B4DFY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

42514:traf2a
gene id: 42514:traf2a
uniprot id: A0A3B4EAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

42514:LOC108429565
gene id: 42514:LOC108429565
uniprot id: A0A3B4CPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Membrane
messages: Mitochondrion inner membrane

42514:timm50
gene id: 42514:timm50
uniprot id: A0A3B4C0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

42514:znf532
gene id: 42514:znf532
uniprot id: A0A3B4EEQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

42514:gabra6a
gene id: 42514:gabra6a
uniprot id: A0A3B4D0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

42514:stam2
gene id: 42514:stam2
uniprot id: A0A3B4D9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

42514:otud7a
gene id: 42514:otud7a
uniprot id: A0A3B4DUD4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:cax2
gene id: 42514:cax2
uniprot id: A0A3B4E5G6
names: Subcellular Location Annotation
messages: Membrane

42514:si:ch73-233f7.1
gene id: 42514:si:ch73-233f7.1
uniprot id: A0A3B4DST7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

42514:bmp6
gene id: 42514:bmp6
uniprot id: A0A3B4D6I8
names: Similarity
messages: Belongs to the TGF-beta family.

42514:c1galt1a
gene id: 42514:c1galt1a
uniprot id: A0A3B4D1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

42514:taf7
gene id: 42514:taf7
uniprot id: A0A3B4E7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

42514:gclm
gene id: 42514:gclm
uniprot id: A0A3B4CL81
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

42514:myoz1a
gene id: 42514:myoz1a
uniprot id: A0A3B4DIW7
names: Similarity
messages: Belongs to the myozenin family.

42514:dusp16
gene id: 42514:dusp16
uniprot id: A0A3B4EMF6
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

42514:batf
gene id: 42514:batf
uniprot id: A0A3B4CX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

42514:rxfp3.2b
gene id: 42514:rxfp3.2b
uniprot id: A0A3B4DUX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

42514:cdk5rap3
gene id: 42514:cdk5rap3
uniprot id: A0A3B4BSY1
names: Similarity
messages: Belongs to the CDK5RAP3 family.

42514:LOC108411158
gene id: 42514:LOC108411158
uniprot id: A0A3B4CER2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

42514:xirp2a
gene id: 42514:xirp2a
uniprot id: A0A3B4CQ80
names: Domain
names: Similarity
messages: Belongs to the Xin family.
messages: Xin repeats bind F-actin.

42514:hopx
gene id: 42514:hopx
uniprot id: A0A3B4ECW4
names: Subcellular Location Annotation
messages: Nucleus

42514:fahd2a
gene id: 42514:fahd2a
uniprot id: A0A3B4E438
names: Similarity
messages: Belongs to the FAH family.

42514:dclre1c
gene id: 42514:dclre1c
uniprot id: A0A3B4DPU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

42514:adam28
gene id: 42514:adam28
uniprot id: A0A3B4ECZ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:esd
gene id: 42514:esd
uniprot id: A0A3B4DIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

42514:LOC108435922
gene id: 42514:LOC108435922
uniprot id: A0A3B4C4W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

42514:scocb
gene id: 42514:scocb
uniprot id: A0A3B4ELN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

42514:lyn
gene id: 42514:lyn
uniprot id: A0A3B4CZ93
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

42514:foxp3b
gene id: 42514:foxp3b
uniprot id: A0A3B4CJJ9
names: Subcellular Location Annotation
messages: Nucleus

42514:ndufa3
gene id: 42514:ndufa3
uniprot id: A0A3B4E4X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA3 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Membrane
messages: Mitochondrion inner membrane

42514:pde6b
gene id: 42514:pde6b
uniprot id: A0A3B4BZ43
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

42514:spaca4l
gene id: 42514:spaca4l
uniprot id: A0A3B4DZ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

42514:LOC108431654
gene id: 42514:LOC108431654
uniprot id: A0A3B4DAC2
names: Similarity
messages: Belongs to the FAM13 family.

42514:LOC108430216
gene id: 42514:LOC108430216
uniprot id: A0A3B4C3P1
names: Subcellular Location Annotation
messages: Membrane

42514:lft1
gene id: 42514:lft1
uniprot id: A0A3B4BQP3
names: Similarity
messages: Belongs to the TGF-beta family.

42514:spon1b
gene id: 42514:spon1b
uniprot id: A0A3B4BUZ4
names: Subcellular Location Annotation
messages: extracellular matrix

42514:mkxb
gene id: 42514:mkxb
uniprot id: A0A3B4C7J1
names: Subcellular Location Annotation
messages: Nucleus

42514:slc6a4b
gene id: 42514:slc6a4b
uniprot id: A0A3B4DMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

42514:cacng2a
gene id: 42514:cacng2a
uniprot id: A0A3B4DFR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

42514:LOC108433148
gene id: 42514:LOC108433148
uniprot id: A0A3B4DQC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

42514:cct5
gene id: 42514:cct5
uniprot id: A0A3B4E5E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

42514:slc7a10b
gene id: 42514:slc7a10b
uniprot id: A0A3B4CI34
names: Subcellular Location Annotation
messages: Membrane

42514:cavin2b
gene id: 42514:cavin2b
uniprot id: A0A3B4DLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

42514:LOC108425609
gene id: 42514:LOC108425609
uniprot id: A0A3B4CC92
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

42514:bud13
gene id: 42514:bud13
uniprot id: A0A3B4CFP5
names: Similarity
messages: Belongs to the CWC26 family.

42514:foxl1
gene id: 42514:foxl1
uniprot id: A0A3B4E385
names: Subcellular Location Annotation
messages: Nucleus

42514:kalrna
gene id: 42514:kalrna
uniprot id: A0A3B4CNE7
uniprot id: A0A3B4E6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

42514:slc25a37
gene id: 42514:slc25a37
uniprot id: A0A3B4CSF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

42514:tmcc1a
gene id: 42514:tmcc1a
uniprot id: A0A3B4BKB3
uniprot id: A0A3B4BP45
uniprot id: A0A3B4DIS0
names: Similarity
messages: Belongs to the TEX28 family.

42514:irf4b
gene id: 42514:irf4b
uniprot id: A0A3B4D374
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

42514:LOC108441239
gene id: 42514:LOC108441239
uniprot id: A0A3B4EK85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:usp20
gene id: 42514:usp20
uniprot id: A0A3B4EP07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: centrosome
messages: perinuclear region

42514:scn1ba
gene id: 42514:scn1ba
uniprot id: A0A3B4EAS9
names: Subcellular Location Annotation
messages: Membrane

42514:atp5if1a
gene id: 42514:atp5if1a
uniprot id: A0A3B4CX78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

42514:eif1b
gene id: 42514:eif1b
uniprot id: A0A3B4D3G0
names: Similarity
messages: Belongs to the SUI1 family.

42514:LOC108411494
gene id: 42514:LOC108411494
uniprot id: A0A3B4EJ54
names: Subcellular Location Annotation
messages: Nucleus

42514:tfeb
gene id: 42514:tfeb
uniprot id: A0A3B4DTJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

42514:ctnnd1
gene id: 42514:ctnnd1
uniprot id: A0A3B4CDB3
uniprot id: A0A3B4CDD3
names: Similarity
messages: Belongs to the beta-catenin family.

42514:LOC108436344
gene id: 42514:LOC108436344
uniprot id: A0A3B4C4A9
uniprot id: A0A3B4DS90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

42514:prkcba
gene id: 42514:prkcba
uniprot id: A0A3B4DZF2
uniprot id: A0A3B4DZG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

42514:pitx2
gene id: 42514:pitx2
uniprot id: A0A3B4CRJ5
uniprot id: A0A3B4CRM1
uniprot id: A0A3B4CTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

42514:ano11
gene id: 42514:ano11
uniprot id: A0A3B4CUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

42514:abcc3
gene id: 42514:abcc3
uniprot id: A0A3B4BRV6
uniprot id: A0A3B4DMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

42514:vps33a
gene id: 42514:vps33a
uniprot id: A0A3B4EAP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

42514:cacng5b
gene id: 42514:cacng5b
uniprot id: A0A3B4DFP9
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

42514:h3f3c
gene id: 42514:h3f3c
uniprot id: A0A3B4BZQ6
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

42514:mrpl28
gene id: 42514:mrpl28
uniprot id: A0A3B4DMF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

42514:lrrc8db
gene id: 42514:lrrc8db
uniprot id: A0A3B4BT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

42514:slc17a6a
gene id: 42514:slc17a6a
uniprot id: A0A3B4BMJ3
names: Subcellular Location Annotation
messages: Membrane

42514:kcnj3a
gene id: 42514:kcnj3a
uniprot id: A0A3B4E371
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

42514:cbfb
gene id: 42514:cbfb
uniprot id: A0A3B4CL21
uniprot id: A0A3B4CL31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

42514:gdf9
gene id: 42514:gdf9
uniprot id: A0A3B4D3F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

42514:degs2
gene id: 42514:degs2
uniprot id: A0A3B4E789
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

42514:map2k2b
gene id: 42514:map2k2b
uniprot id: A0A3B4EKW8
names: Similarity
messages: Belongs to the protein kinase superfamily.

42514:LOC108441219
gene id: 42514:LOC108441219
uniprot id: A0A3B4E851
names: Caution
names: Similarity
messages: Belongs to the Ntn-hydrolase family.
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ube2d3
gene id: 42514:ube2d3
uniprot id: A0A3B4CDW7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

42514:neurod4
gene id: 42514:neurod4
uniprot id: A0A3B4CZ18
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108431845
gene id: 42514:LOC108431845
uniprot id: A0A3B4E2K6
names: Similarity
messages: Belongs to the cytochrome P450 family.

42514:casp8
gene id: 42514:casp8
uniprot id: A0A3B4DL35
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:LOC108433632
gene id: 42514:LOC108433632
uniprot id: A0A3B4C800
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

42514:LOC108430993
gene id: 42514:LOC108430993
uniprot id: A0A3B4DQ74
names: Similarity
messages: Belongs to the SLT11 family.

42514:pdcd4a
gene id: 42514:pdcd4a
uniprot id: A0A3B4C4A8
names: Similarity
messages: Belongs to the PDCD4 family.

42514:cript
gene id: 42514:cript
uniprot id: A0A3B4BX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

42514:lamb1a
gene id: 42514:lamb1a
uniprot id: A0A3B4E4I4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

42514:LOC108424050
gene id: 42514:LOC108424050
uniprot id: A0A3B4BYG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

42514:galnt10
gene id: 42514:galnt10
uniprot id: A0A3B4CWD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

42514:ddx51
gene id: 42514:ddx51
uniprot id: A0A3B4E5U0
names: Similarity
messages: Belongs to the DEAD box helicase family.

42514:pdgfra
gene id: 42514:pdgfra
uniprot id: A0A3B4BUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

42514:si:ch211-276f18.2
gene id: 42514:si:ch211-276f18.2
uniprot id: A0A3B4CVI7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

42514:LOC108435910
gene id: 42514:LOC108435910
uniprot id: A0A3B4C5R2
names: Subcellular Location Annotation
messages: Membrane

42514:rbpjb
gene id: 42514:rbpjb
uniprot id: A0A3B4C2R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

42514:saxo2
gene id: 42514:saxo2
uniprot id: A0A3B4C4Z8
names: Similarity
messages: Belongs to the FAM154 family.

42514:fgfbp1b
gene id: 42514:fgfbp1b
uniprot id: A0A3B4BS76
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

42514:igfbp6a
gene id: 42514:igfbp6a
uniprot id: A0A3B4BQR1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

42514:tnpo2
gene id: 42514:tnpo2
uniprot id: A0A3B4D3J7
uniprot id: A0A3B4D4L1
names: Subcellular Location Annotation
messages: Cytoplasm

42514:LOC108423292
gene id: 42514:LOC108423292
uniprot id: A0A3B4C5N8
names: Similarity
messages: Belongs to the strictosidine synthase family.

42514:cntnap2b
gene id: 42514:cntnap2b
uniprot id: A0A3B4C6Z4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

42514:noxred1
gene id: 42514:noxred1
uniprot id: A0A3B4E2G8
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

42514:ss18
gene id: 42514:ss18
uniprot id: A0A3B4BPF9
uniprot id: A0A3B4DHM2
names: Similarity
messages: Belongs to the SS18 family.

42514:zc2hc1c
gene id: 42514:zc2hc1c
uniprot id: A0A3B4DMW3
names: Similarity
messages: Belongs to the ZC2HC1 family.

42514:tmed7
gene id: 42514:tmed7
uniprot id: A0A3B4CAN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

42514:ssu72
gene id: 42514:ssu72
uniprot id: A0A3B4E6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

42514:zpr1
gene id: 42514:zpr1
uniprot id: A0A3B4DJI7
names: Similarity
messages: Belongs to the ZPR1 family.

42514:sema6a
gene id: 42514:sema6a
uniprot id: A0A3B4BV05
uniprot id: A0A3B4DMY2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:rpl7l1
gene id: 42514:rpl7l1
uniprot id: A0A3B4ENY8
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

42514:slc1a2a
gene id: 42514:slc1a2a
uniprot id: A0A3B4BRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

42514:phyhipla
gene id: 42514:phyhipla
uniprot id: A0A3B4EJT6
names: Similarity
messages: Belongs to the PHYHIP family.

42514:prkaa2
gene id: 42514:prkaa2
uniprot id: A0A3B4DG22
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

42514:zfp36l2
gene id: 42514:zfp36l2
uniprot id: A0A3B4BXK9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

42514:pdgfrl
gene id: 42514:pdgfrl
uniprot id: A0A3B4E807
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Secreted

42514:rabep2
gene id: 42514:rabep2
uniprot id: A0A3B4CZR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Early endosome
messages: Endosome
messages: centrosome
messages: cilium basal body

42514:tmem8b
gene id: 42514:tmem8b
uniprot id: A0A3B4C9G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

42514:patj
gene id: 42514:patj
uniprot id: A0A3B4ECQ8
names: Subcellular Location Annotation
messages: tight junction

42514:LOC108424780
gene id: 42514:LOC108424780
uniprot id: A0A3B4DFF3
names: Similarity
messages: Belongs to the importin alpha family.

42514:LOC108431910
gene id: 42514:LOC108431910
uniprot id: A0A3B4CA23
names: Similarity
messages: Belongs to the NXPE family.

42514:aqp9b
gene id: 42514:aqp9b
uniprot id: A0A3B4EBN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

42514:tnfsf10l4
gene id: 42514:tnfsf10l4
uniprot id: A0A3B4BPP2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

42514:LOC108413192
gene id: 42514:LOC108413192
uniprot id: A0A3B4BUC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

42514:LOC108435733
gene id: 42514:LOC108435733
uniprot id: A0A3B4CML8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

42514:pomt2
gene id: 42514:pomt2
uniprot id: A0A3B4CX17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

42514:ppm1nb
gene id: 42514:ppm1nb
uniprot id: A0A3B4CII1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

42514:gtdc1
gene id: 42514:gtdc1
uniprot id: A0A3B4DVR2
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

42514:ppil1
gene id: 42514:ppil1
uniprot id: A0A3B4CEW4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

42514:st8sia6
gene id: 42514:st8sia6
uniprot id: A0A3B4DRV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

42514:si:ch1073-272o11.3
gene id: 42514:si:ch1073-272o11.3
uniprot id: A0A3B4BR07
names: Similarity
messages: Belongs to the CDR2 family.

42514:faah2b
gene id: 42514:faah2b
uniprot id: A0A3B4CUF4
names: Similarity
messages: Belongs to the amidase family.

42514:vps26c
gene id: 42514:vps26c
uniprot id: A0A3B4DPY4
names: Similarity
messages: Belongs to the VPS26 family.

42514:abraxas2
gene id: 42514:abraxas2
uniprot id: A0A3B4CVD8
names: Subcellular Location Annotation
messages: Nucleus

42514:cdk5r2b
gene id: 42514:cdk5r2b
uniprot id: A0A3B4C5Y3
names: Similarity
messages: Belongs to the cyclin-dependent kinase 5 activator family.

42514:cpm
gene id: 42514:cpm
uniprot id: A0A3B4BWB5
names: Similarity
messages: Belongs to the peptidase M14 family.

42514:LOC108424060
gene id: 42514:LOC108424060
uniprot id: A0A3B4BXF7
names: Similarity
messages: Belongs to the peptidase C14A family.

42514:pex3
gene id: 42514:pex3
uniprot id: A0A3B4ELJ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane

42514:gjc2
gene id: 42514:gjc2
uniprot id: A0A3B4DH05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:LOC108412992
gene id: 42514:LOC108412992
uniprot id: A0A3B4CBZ1
uniprot id: A0A3B4DX46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

42514:cavin4a
gene id: 42514:cavin4a
uniprot id: A0A3B4E8S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

42514:nlk2
gene id: 42514:nlk2
uniprot id: A0A3B4CFJ1
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

42514:chmp5b
gene id: 42514:chmp5b
uniprot id: A0A3B4CWU4
names: Similarity
messages: Belongs to the SNF7 family.

42514:naa38
gene id: 42514:naa38
uniprot id: A0A3B4CRS2
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

42514:traf1
gene id: 42514:traf1
uniprot id: A0A3B4EGX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

42514:copb2
gene id: 42514:copb2
uniprot id: A0A3B4D348
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

42514:e2f5
gene id: 42514:e2f5
uniprot id: A0A3B4D7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

42514:hoga1
gene id: 42514:hoga1
uniprot id: A0A3B4D572
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

42514:bbs4
gene id: 42514:bbs4
uniprot id: A0A3B4D3A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

42514:coq9
gene id: 42514:coq9
uniprot id: A0A3B4DUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

42514:ezh2
gene id: 42514:ezh2
uniprot id: A0A3B4CJA3
names: Subcellular Location Annotation
messages: Nucleus

42514:LOC108412648
gene id: 42514:LOC108412648
uniprot id: A0A3B4EKC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

42514:sar1b
gene id: 42514:sar1b
uniprot id: A0A3B4CCT7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

42514:lamc2
gene id: 42514:lamc2
uniprot id: A0A3B4BZP0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

42514:nubpl
gene id: 42514:nubpl
uniprot id: A0A3B4EDV8
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

42514:marveld3
gene id: 42514:marveld3
uniprot id: A0A3B4E071
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108424260
gene id: 42514:LOC108424260
uniprot id: A0A3B4EFQ5
names: Subcellular Location Annotation
messages: Membrane

42514:sdc4
gene id: 42514:sdc4
uniprot id: A0A3B4D1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Belongs to the syndecan proteoglycan family.
messages: Membrane

42514:surf4l
gene id: 42514:surf4l
uniprot id: A0A3B4D504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

42514:efnb2a
gene id: 42514:efnb2a
uniprot id: A0A3B4DW93
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:f3b
gene id: 42514:f3b
uniprot id: A0A3B4DT78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

42514:alg10
gene id: 42514:alg10
uniprot id: A0A3B4EP75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

42514:slc40a1
gene id: 42514:slc40a1
uniprot id: A0A3B4CWC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

42514:LOC108411971
gene id: 42514:LOC108411971
uniprot id: A0A3B4C1K5
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

42514:hexb
gene id: 42514:hexb
uniprot id: A0A3B4CPK3
uniprot id: A0A3B4E7H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

42514:LOC108433637
gene id: 42514:LOC108433637
uniprot id: A0A3B4DY61
names: Subcellular Location Annotation
messages: Membrane

42514:LOC108432603
gene id: 42514:LOC108432603
uniprot id: A0A3B4DJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

42514:nradd
gene id: 42514:nradd
uniprot id: A0A3B4BYX9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

42514:ipmka
gene id: 42514:ipmka
uniprot id: A0A3B4DGI2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

42514:mab21l2
gene id: 42514:mab21l2
uniprot id: A0A3B4E9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

42514:fam102ab
gene id: 42514:fam102ab
uniprot id: A0A3B4CAL0
names: Similarity
messages: Belongs to the FAM102 family.

42514:tmem53
gene id: 42514:tmem53
uniprot id: A0A3B4DHX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

42514:otub1a
gene id: 42514:otub1a
uniprot id: A0A3B4C6V9
names: Similarity
messages: Belongs to the peptidase C65 family.

42514:hsd20b2
gene id: 42514:hsd20b2
uniprot id: A0A3B4CC36
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:arsj
gene id: 42514:arsj
uniprot id: A0A3B4CSP3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

42514:LOC108442170
gene id: 42514:LOC108442170
uniprot id: A0A3B4ELG7
names: Similarity
messages: Belongs to the SLITRK family.

42514:nr2c2
gene id: 42514:nr2c2
uniprot id: A0A3B4BP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

42514:nme2a
gene id: 42514:nme2a
uniprot id: A0A3B4BZY3
uniprot id: A0A3B4DQZ2
names: Similarity
messages: Belongs to the NDK family.

42514:aqp3a
gene id: 42514:aqp3a
uniprot id: A0A3B4DUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

42514:amotl1
gene id: 42514:amotl1
uniprot id: A0A3B4CKX2
names: Similarity
messages: Belongs to the angiomotin family.

42514:kcnj15
gene id: 42514:kcnj15
uniprot id: A0A3B4CLU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

42514:dnajc2
gene id: 42514:dnajc2
uniprot id: A0A3B4E5B1
names: Subcellular Location Annotation
messages: cytosol

42514:ehd1a
gene id: 42514:ehd1a
uniprot id: A0A3B4D009
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

42514:wasf2
gene id: 42514:wasf2
uniprot id: A0A3B4EJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

42514:qpctla
gene id: 42514:qpctla
uniprot id: A0A3B4CQC7
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

42514:larp7
gene id: 42514:larp7
uniprot id: A0A3B4CIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

42514:si:dkey-174n20.1
gene id: 42514:si:dkey-174n20.1
uniprot id: A0A3B4BZW9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

42514:LOC108427753
gene id: 42514:LOC108427753
uniprot id: A0A3B4D2V7
uniprot id: A0A3B4EG31
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

42514:tlcd3bb
gene id: 42514:tlcd3bb
uniprot id: A0A3B4D9T0
names: Subcellular Location Annotation
messages: Membrane

42514:mlf1
gene id: 42514:mlf1
uniprot id: A0A3B4BVF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

42514:LOC108430517
gene id: 42514:LOC108430517
uniprot id: A0A3B4D5Y3
names: Similarity
messages: Belongs to the importin alpha family.

42514:otop2
gene id: 42514:otop2
uniprot id: A0A3B4EPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

42514:dyrk1b
gene id: 42514:dyrk1b
uniprot id: A0A3B4EBS7
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

42514:LOC108431615
gene id: 42514:LOC108431615
uniprot id: A0A3B4DCC9
uniprot id: A0A3B4DDY3
names: Similarity
messages: Belongs to the filamin family.

42514:gja10a
gene id: 42514:gja10a
uniprot id: A0A3B4BU85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

42514:parp12a
gene id: 42514:parp12a
uniprot id: A0A3B4CXA8
names: Similarity
messages: Belongs to the ARTD/PARP family.

42514:yars2
gene id: 42514:yars2
uniprot id: A0A3B4EGK0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

42514:rc3h1b
gene id: 42514:rc3h1b
uniprot id: A0A3B4E469
names: Subcellular Location Annotation
messages: P-body

42514:thoc7
gene id: 42514:thoc7
uniprot id: A0A3B4DZL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

42514:elp2
gene id: 42514:elp2
uniprot id: A0A3B4BRI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus