425104:SSED RS01990
gene id: 425104:SSED_RS01990
uniprot id: A8FQ77
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

425104:SSED RS07645
gene id: 425104:SSED_RS07645
uniprot id: A8FTB4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

425104:SSED RS02290
gene id: 425104:SSED_RS02290
uniprot id: A8FQC3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

425104:SSED RS02340
gene id: 425104:SSED_RS02340
uniprot id: A8FQD3
names: Similarity
messages: Belongs to the GARS family.

425104:SSED RS18220
gene id: 425104:SSED_RS18220
uniprot id: A8FZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

425104:SSED RS06430
gene id: 425104:SSED_RS06430
uniprot id: A8FSN9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

425104:SSED RS01345
gene id: 425104:SSED_RS01345
uniprot id: A8FPV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

425104:SSED RS03215
gene id: 425104:SSED_RS03215
uniprot id: A8FQV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

425104:SSED RS16695
gene id: 425104:SSED_RS16695
uniprot id: A8FY70
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

425104:SSED RS16905
gene id: 425104:SSED_RS16905
uniprot id: A8FYB1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

425104:SSED RS06325
gene id: 425104:SSED_RS06325
uniprot id: A8FSL8
names: Similarity
messages: Belongs to the YggT family.

425104:SSED RS18785
gene id: 425104:SSED_RS18785
uniprot id: A8FZC0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS02445
gene id: 425104:SSED_RS02445
uniprot id: A8FQF4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

425104:SSED RS22480
gene id: 425104:SSED_RS22480
uniprot id: A8G1E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

425104:SSED RS14495
gene id: 425104:SSED_RS14495
uniprot id: A8FX04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

425104:SSED RS00685
gene id: 425104:SSED_RS00685
uniprot id: A8FPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS05155
gene id: 425104:SSED_RS05155
uniprot id: A8FRZ2
names: Similarity
messages: Belongs to the MEMO1 family.

425104:SSED RS14500
gene id: 425104:SSED_RS14500
uniprot id: A8FX05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S51 family.
messages: Cytoplasm
messages: Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.

425104:SSED RS14905
gene id: 425104:SSED_RS14905
uniprot id: A8FX86
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

425104:SSED RS02375
gene id: 425104:SSED_RS02375
uniprot id: A8FQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

425104:SSED RS00315
gene id: 425104:SSED_RS00315
uniprot id: A8FP99
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

425104:SSED RS14640
gene id: 425104:SSED_RS14640
uniprot id: A8FX34
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

425104:SSED RS03995
gene id: 425104:SSED_RS03995
uniprot id: A8FRB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

425104:SSED RS16955
gene id: 425104:SSED_RS16955
uniprot id: A8FYC1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS19165
gene id: 425104:SSED_RS19165
uniprot id: A8FZJ6
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS04625
gene id: 425104:SSED_RS04625
uniprot id: A8FRN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

425104:SSED RS02860
gene id: 425104:SSED_RS02860
uniprot id: A8FQN6
names: Similarity
messages: Belongs to the GSP E family.

425104:SSED RS13460
gene id: 425104:SSED_RS13460
uniprot id: A8FWE6
names: Similarity
messages: Belongs to the universal stress protein A family.

425104:SSED RS02535
gene id: 425104:SSED_RS02535
uniprot id: A8FQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS20550
gene id: 425104:SSED_RS20550
uniprot id: A8G0B8
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

425104:SSED RS05855
gene id: 425104:SSED_RS05855
uniprot id: A8FSC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

425104:SSED RS04230
gene id: 425104:SSED_RS04230
uniprot id: A8FRF7
names: Similarity
messages: Belongs to the peptidase S8 family.

425104:SSED RS08825
gene id: 425104:SSED_RS08825
uniprot id: A8FTZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS13365
gene id: 425104:SSED_RS13365
uniprot id: A8FWC9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

425104:SSED RS17865
gene id: 425104:SSED_RS17865
uniprot id: A8FYV1
names: Similarity
messages: Belongs to the peptidase M17 family.

425104:SSED RS13995
gene id: 425104:SSED_RS13995
uniprot id: A8FWQ3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

425104:SSED RS00345
gene id: 425104:SSED_RS00345
uniprot id: A8FPA5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

425104:SSED RS18375
gene id: 425104:SSED_RS18375
uniprot id: A8FZ39
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

425104:SSED RS16805
gene id: 425104:SSED_RS16805
uniprot id: A8FY91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

425104:SSED RS05670
gene id: 425104:SSED_RS05670
uniprot id: A8FS91
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS05620
gene id: 425104:SSED_RS05620
uniprot id: A8FS81
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS16325
gene id: 425104:SSED_RS16325
uniprot id: A8FXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

425104:SSED RS08860
gene id: 425104:SSED_RS08860
uniprot id: A8FU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

425104:SSED RS13350
gene id: 425104:SSED_RS13350
uniprot id: A8FWC6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

425104:SSED RS17735
gene id: 425104:SSED_RS17735
uniprot id: A8FYS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

425104:SSED RS12120
gene id: 425104:SSED_RS12120
uniprot id: A8FVP8
names: Similarity
messages: Belongs to the asparaginase 1 family.

425104:SSED RS03925
gene id: 425104:SSED_RS03925
uniprot id: A8FRA1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

425104:SSED RS09240
gene id: 425104:SSED_RS09240
uniprot id: A8FU72
names: Similarity
messages: Belongs to the UPF0319 family.

425104:SSED RS01995
gene id: 425104:SSED_RS01995
uniprot id: A8FQ78
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

425104:SSED RS17995
gene id: 425104:SSED_RS17995
uniprot id: A8FYX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

425104:SSED RS08820
gene id: 425104:SSED_RS08820
uniprot id: A8FTZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

425104:SSED RS00525
gene id: 425104:SSED_RS00525
uniprot id: A8FPE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

425104:SSED RS01220
gene id: 425104:SSED_RS01220
uniprot id: A8FPS9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS15675
gene id: 425104:SSED_RS15675
uniprot id: A8FXM0
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS15305
gene id: 425104:SSED_RS15305
uniprot id: A8FXE7
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS11145
gene id: 425104:SSED_RS11145
uniprot id: A8FV68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

425104:SSED RS17750
gene id: 425104:SSED_RS17750
uniprot id: A8FYS6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

425104:SSED RS00605
gene id: 425104:SSED_RS00605
uniprot id: A8FPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

425104:SSED RS15145
gene id: 425104:SSED_RS15145
uniprot id: A8FXD6
names: Similarity
messages: Belongs to the DEAD box helicase family.

425104:SSED RS02130
gene id: 425104:SSED_RS02130
uniprot id: A8FQA5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

425104:SSED RS05610
gene id: 425104:SSED_RS05610
uniprot id: A8FS79
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

425104:SSED RS07175
gene id: 425104:SSED_RS07175
uniprot id: A8FT24
names: Similarity
messages: Belongs to the OsmC/Ohr family.

425104:SSED RS17850
gene id: 425104:SSED_RS17850
uniprot id: A8FYU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

425104:SSED RS20905
gene id: 425104:SSED_RS20905
uniprot id: A8G0I9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

425104:SSED RS17510
gene id: 425104:SSED_RS17510
uniprot id: A8FYN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

425104:SSED RS21430
gene id: 425104:SSED_RS21430
uniprot id: A8G0U4
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

425104:SSED RS00445
gene id: 425104:SSED_RS00445
uniprot id: A8FPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

425104:SSED RS12195
gene id: 425104:SSED_RS12195
uniprot id: A8FVR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

425104:SSED RS09615
gene id: 425104:SSED_RS09615
uniprot id: A8FUE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

425104:SSED RS19215
gene id: 425104:SSED_RS19215
uniprot id: A8FZK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

425104:SSED RS16535
gene id: 425104:SSED_RS16535
uniprot id: A8FY38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

425104:SSED RS01120
gene id: 425104:SSED_RS01120
uniprot id: A8FPQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

425104:SSED RS09430
gene id: 425104:SSED_RS09430
uniprot id: A8FUA8
names: Similarity
messages: Belongs to the YkuD family.

425104:SSED RS05870
gene id: 425104:SSED_RS05870
uniprot id: A8FSD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

425104:SSED RS12600
gene id: 425104:SSED_RS12600
uniprot id: A8FVZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

425104:SSED RS23500
gene id: 425104:SSED_RS23500
uniprot id: A8G1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

425104:SSED RS17370
gene id: 425104:SSED_RS17370
uniprot id: A8FYK3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS09700
gene id: 425104:SSED_RS09700
uniprot id: A8FUF1
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

425104:SSED RS00135
gene id: 425104:SSED_RS00135
uniprot id: A8FP67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

425104:SSED RS06990
gene id: 425104:SSED_RS06990
uniprot id: A8FSY8
names: Similarity
messages: Belongs to the UPF0178 family.

425104:SSED RS14545
gene id: 425104:SSED_RS14545
uniprot id: A8FX14
names: Similarity
messages: Belongs to the group II decarboxylase family.

425104:SSED RS07940
gene id: 425104:SSED_RS07940
uniprot id: A8FTH1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

425104:SSED RS15105
gene id: 425104:SSED_RS15105
uniprot id: A8FXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

425104:SSED RS03240
gene id: 425104:SSED_RS03240
uniprot id: A8FQW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

425104:SSED RS02715
gene id: 425104:SSED_RS02715
uniprot id: A8FQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

425104:SSED RS06880
gene id: 425104:SSED_RS06880
uniprot id: A8FSW6
names: Similarity
messages: Belongs to the peptidase M16 family.

425104:SSED RS21425
gene id: 425104:SSED_RS21425
uniprot id: A8G0U3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS17220
gene id: 425104:SSED_RS17220
uniprot id: A8FYH3
names: Similarity
messages: Belongs to the GST superfamily.

425104:SSED RS21955
gene id: 425104:SSED_RS21955
uniprot id: A8G142
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

425104:SSED RS08960
gene id: 425104:SSED_RS08960
uniprot id: A8FU22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

425104:SSED RS21790
gene id: 425104:SSED_RS21790
uniprot id: A8G109
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

425104:SSED RS10150
gene id: 425104:SSED_RS10150
uniprot id: A8FUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

425104:SSED RS17440
gene id: 425104:SSED_RS17440
uniprot id: A8FYL7
names: Similarity
messages: Belongs to the DEAD box helicase family.

425104:SSED RS00885
gene id: 425104:SSED_RS00885
uniprot id: A8FPL1
names: Similarity
messages: Belongs to the TPP enzyme family.

425104:SSED RS15750
gene id: 425104:SSED_RS15750
uniprot id: A8FXN4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

425104:SSED RS03490
gene id: 425104:SSED_RS03490
uniprot id: A8FR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

425104:SSED RS22670
gene id: 425104:SSED_RS22670
uniprot id: A8G1H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

425104:SSED RS09100
gene id: 425104:SSED_RS09100
uniprot id: A8FU50
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

425104:SSED RS18235
gene id: 425104:SSED_RS18235
uniprot id: A8FZ17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

425104:SSED RS13930
gene id: 425104:SSED_RS13930
uniprot id: A8FWP0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

425104:SSED RS05550
gene id: 425104:SSED_RS05550
uniprot id: A8FS67
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

425104:SSED RS01465
gene id: 425104:SSED_RS01465
uniprot id: A8FPX2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

425104:SSED RS06400
gene id: 425104:SSED_RS06400
uniprot id: A8FSN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

425104:SSED RS21260
gene id: 425104:SSED_RS21260
uniprot id: A8G0R1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS06350
gene id: 425104:SSED_RS06350
uniprot id: A8FSM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

425104:SSED RS21685
gene id: 425104:SSED_RS21685
uniprot id: A8G0Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS08215
gene id: 425104:SSED_RS08215
uniprot id: A8FTM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

425104:SSED RS10885
gene id: 425104:SSED_RS10885
uniprot id: A8FV25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS20175
gene id: 425104:SSED_RS20175
uniprot id: A8G044
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

425104:SSED RS17720
gene id: 425104:SSED_RS17720
uniprot id: A8FYS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

425104:SSED RS17855
gene id: 425104:SSED_RS17855
uniprot id: A8FYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

425104:SSED RS05225
gene id: 425104:SSED_RS05225
uniprot id: A8FS04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

425104:SSED RS18080
gene id: 425104:SSED_RS18080
uniprot id: A8FYZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

425104:SSED RS02315
gene id: 425104:SSED_RS02315
uniprot id: A8FQC8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

425104:SSED RS01030
gene id: 425104:SSED_RS01030
uniprot id: A8FPP1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell inner membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

425104:SSED RS01900
gene id: 425104:SSED_RS01900
uniprot id: A8FQ59
names: Similarity
messages: Belongs to the UPF0111 family.

425104:SSED RS17660
gene id: 425104:SSED_RS17660
uniprot id: A8FYR0
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

425104:SSED RS06420
gene id: 425104:SSED_RS06420
uniprot id: A8FSN7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

425104:SSED RS17700
gene id: 425104:SSED_RS17700
uniprot id: A8FYR8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

425104:SSED RS15385
gene id: 425104:SSED_RS15385
uniprot id: A8FXG3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

425104:SSED RS22975
gene id: 425104:SSED_RS22975
uniprot id: A8G1N1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

425104:SSED RS22465
gene id: 425104:SSED_RS22465
uniprot id: A8G1E0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

425104:SSED RS17565
gene id: 425104:SSED_RS17565
uniprot id: A8FYP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorD/DmsD family. TorD subfamily.
messages: Cytoplasm
messages: Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.

425104:SSED RS21455
gene id: 425104:SSED_RS21455
uniprot id: A8G0U9
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

425104:SSED RS18460
gene id: 425104:SSED_RS18460
uniprot id: A8FZ56
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS10575
gene id: 425104:SSED_RS10575
uniprot id: A8FUX4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

425104:SSED RS09820
gene id: 425104:SSED_RS09820
uniprot id: A8FUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

425104:SSED RS05730
gene id: 425104:SSED_RS05730
uniprot id: A8FSA3
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

425104:SSED RS17445
gene id: 425104:SSED_RS17445
uniprot id: A8FYL8
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS12350
gene id: 425104:SSED_RS12350
uniprot id: A8FVU3
names: Similarity
messages: Belongs to the peptidase S9C family.

425104:SSED RS00950
gene id: 425104:SSED_RS00950
uniprot id: A8FPM4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS07280
gene id: 425104:SSED_RS07280
uniprot id: A8FT43
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

425104:SSED RS19390
gene id: 425104:SSED_RS19390
uniprot id: A8FZP1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

425104:SSED RS16495
gene id: 425104:SSED_RS16495
uniprot id: A8FY30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

425104:SSED RS15100
gene id: 425104:SSED_RS15100
uniprot id: A8FXC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

425104:SSED RS22335
gene id: 425104:SSED_RS22335
uniprot id: A8G1B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

425104:SSED RS02345
gene id: 425104:SSED_RS02345
uniprot id: A8FQD4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

425104:SSED RS19445
gene id: 425104:SSED_RS19445
uniprot id: A8FZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

425104:SSED RS06025
gene id: 425104:SSED_RS06025
uniprot id: A8FSG2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS16030
gene id: 425104:SSED_RS16030
uniprot id: A8FXU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

425104:SSED RS07395
gene id: 425104:SSED_RS07395
uniprot id: A8FT66
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS19900
gene id: 425104:SSED_RS19900
uniprot id: A8FZY9
names: Similarity
messages: Belongs to the MipA/OmpV family.

425104:SSED RS00635
gene id: 425104:SSED_RS00635
uniprot id: A8FPG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

425104:SSED RS13335
gene id: 425104:SSED_RS13335
uniprot id: A8FWC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

425104:SSED RS10890
gene id: 425104:SSED_RS10890
uniprot id: A8FV26
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

425104:SSED RS23465
gene id: 425104:SSED_RS23465
uniprot id: A8G1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

425104:SSED RS19520
gene id: 425104:SSED_RS19520
uniprot id: A8FZR5
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

425104:SSED RS09885
gene id: 425104:SSED_RS09885
uniprot id: A8FUJ0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

425104:SSED RS06630
gene id: 425104:SSED_RS06630
uniprot id: A8FSS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

425104:SSED RS13195
gene id: 425104:SSED_RS13195
uniprot id: A8FW96
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

425104:SSED RS14950
gene id: 425104:SSED_RS14950
uniprot id: A8FX96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

425104:SSED RS11685
gene id: 425104:SSED_RS11685
uniprot id: A8FVG2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

425104:SSED RS15595
gene id: 425104:SSED_RS15595
uniprot id: A8FXK4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

425104:SSED RS15225
gene id: 425104:SSED_RS15225
uniprot id: A8FXE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

425104:SSED RS13230
gene id: 425104:SSED_RS13230
uniprot id: A8FWA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

425104:SSED RS23800
gene id: 425104:SSED_RS23800
uniprot id: A8FP45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

425104:SSED RS15960
gene id: 425104:SSED_RS15960
uniprot id: A8FXS6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

425104:SSED RS01700
gene id: 425104:SSED_RS01700
uniprot id: A8FQ19
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

425104:SSED RS12020
gene id: 425104:SSED_RS12020
uniprot id: A8FVM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

425104:SSED RS18065
gene id: 425104:SSED_RS18065
uniprot id: A8FYZ1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

425104:SSED RS22415
gene id: 425104:SSED_RS22415
uniprot id: A8G1D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

425104:SSED RS10815
gene id: 425104:SSED_RS10815
uniprot id: A8FV11
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS10605
gene id: 425104:SSED_RS10605
uniprot id: A8FUY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

425104:SSED RS05890
gene id: 425104:SSED_RS05890
uniprot id: A8FSD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

425104:SSED RS02920
gene id: 425104:SSED_RS02920
uniprot id: A8FQP8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

425104:SSED RS19170
gene id: 425104:SSED_RS19170
uniprot id: A8FZJ7
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS18730
gene id: 425104:SSED_RS18730
uniprot id: A8FZA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS08660
gene id: 425104:SSED_RS08660
uniprot id: A8FTW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

425104:SSED RS01715
gene id: 425104:SSED_RS01715
uniprot id: A8FQ22
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS04960
gene id: 425104:SSED_RS04960
uniprot id: A8FRV3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

425104:SSED RS20295
gene id: 425104:SSED_RS20295
uniprot id: A8G067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS04445
gene id: 425104:SSED_RS04445
uniprot id: A8FRK0
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS09625
gene id: 425104:SSED_RS09625
uniprot id: A8FUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

425104:SSED RS05000
gene id: 425104:SSED_RS05000
uniprot id: A8FRW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

425104:SSED RS21420
gene id: 425104:SSED_RS21420
uniprot id: A8G0U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

425104:SSED RS12765
gene id: 425104:SSED_RS12765
uniprot id: A8FW24
names: Similarity
messages: Belongs to the ArsC family.

425104:SSED RS22275
gene id: 425104:SSED_RS22275
uniprot id: A8G1A5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS06675
gene id: 425104:SSED_RS06675
uniprot id: A8FST8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

425104:SSED RS11015
gene id: 425104:SSED_RS11015
uniprot id: A8FV49
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

425104:SSED RS06175
gene id: 425104:SSED_RS06175
uniprot id: A8FSJ2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS01725
gene id: 425104:SSED_RS01725
uniprot id: A8FQ24
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

425104:SSED RS02305
gene id: 425104:SSED_RS02305
uniprot id: A8FQC6
names: Similarity
messages: Belongs to the peptidase M13 family.

425104:SSED RS12820
gene id: 425104:SSED_RS12820
uniprot id: A8FW35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

425104:SSED RS18670
gene id: 425104:SSED_RS18670
uniprot id: A8FZ97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS01425
gene id: 425104:SSED_RS01425
uniprot id: A8FPX1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00450
gene id: 425104:SSED_RS00450
uniprot id: A8FPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

425104:SSED RS22735
gene id: 425104:SSED_RS22735
uniprot id: A8G1I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS14740
gene id: 425104:SSED_RS14740
uniprot id: A8FX54
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS23740
gene id: 425104:SSED_RS23740
uniprot id: A8FYM5
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS04665
gene id: 425104:SSED_RS04665
uniprot id: A8FRP4
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS17740
gene id: 425104:SSED_RS17740
uniprot id: A8FYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

425104:SSED RS15310
gene id: 425104:SSED_RS15310
uniprot id: A8FXE8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS07700
gene id: 425104:SSED_RS07700
uniprot id: A8FTC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS00370
gene id: 425104:SSED_RS00370
uniprot id: A8FPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

425104:SSED RS00440
gene id: 425104:SSED_RS00440
uniprot id: A8FPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

425104:SSED RS06915
gene id: 425104:SSED_RS06915
uniprot id: A8FSX3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

425104:SSED RS02060
gene id: 425104:SSED_RS02060
uniprot id: A8FQ91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

425104:SSED RS04615
gene id: 425104:SSED_RS04615
uniprot id: A8FRN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS21100
gene id: 425104:SSED_RS21100
uniprot id: A8G0M8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

425104:SSED RS13795
gene id: 425104:SSED_RS13795
uniprot id: A8FWL3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

425104:SSED RS08875
gene id: 425104:SSED_RS08875
uniprot id: A8FU05
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS16300
gene id: 425104:SSED_RS16300
uniprot id: A8FXZ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS00155
gene id: 425104:SSED_RS00155
uniprot id: A8FP71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

425104:SSED RS04970
gene id: 425104:SSED_RS04970
uniprot id: A8FRV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

425104:SSED RS09280
gene id: 425104:SSED_RS09280
uniprot id: A8FU80
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

425104:SSED RS18530
gene id: 425104:SSED_RS18530
uniprot id: A8FZ70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

425104:SSED RS04605
gene id: 425104:SSED_RS04605
uniprot id: A8FRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

425104:SSED RS16370
gene id: 425104:SSED_RS16370
uniprot id: A8FY06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

425104:SSED RS03745
gene id: 425104:SSED_RS03745
uniprot id: A8FR66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

425104:SSED RS08970
gene id: 425104:SSED_RS08970
uniprot id: A8FU25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

425104:SSED RS08045
gene id: 425104:SSED_RS08045
uniprot id: A8FTI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS09970
gene id: 425104:SSED_RS09970
uniprot id: A8FUK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

425104:SSED RS07770
gene id: 425104:SSED_RS07770
uniprot id: A8FTD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS07485
gene id: 425104:SSED_RS07485
uniprot id: A8FT83
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

425104:SSED RS21350
gene id: 425104:SSED_RS21350
uniprot id: A8G0S9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS14985
gene id: 425104:SSED_RS14985
uniprot id: A8FXA3
names: Similarity
messages: Belongs to the HesB/IscA family.

425104:SSED RS21865
gene id: 425104:SSED_RS21865
uniprot id: A8G124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

425104:SSED RS16060
gene id: 425104:SSED_RS16060
uniprot id: A8FXU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

425104:SSED RS04805
gene id: 425104:SSED_RS04805
uniprot id: A8FRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

425104:SSED RS22955
gene id: 425104:SSED_RS22955
uniprot id: A8G1M7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

425104:SSED RS07595
gene id: 425104:SSED_RS07595
uniprot id: A8FTA4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

425104:SSED RS19540
gene id: 425104:SSED_RS19540
uniprot id: A8FZR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

425104:SSED RS14505
gene id: 425104:SSED_RS14505
uniprot id: A8FX06
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

425104:SSED RS21490
gene id: 425104:SSED_RS21490
uniprot id: A8G0V5
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS21985
gene id: 425104:SSED_RS21985
uniprot id: A8G148
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS13695
gene id: 425104:SSED_RS13695
uniprot id: A8FWJ3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

425104:SSED RS11950
gene id: 425104:SSED_RS11950
uniprot id: A8FVL4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

425104:SSED RS07690
gene id: 425104:SSED_RS07690
uniprot id: A8FTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

425104:SSED RS14975
gene id: 425104:SSED_RS14975
uniprot id: A8FXA1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

425104:SSED RS22660
gene id: 425104:SSED_RS22660
uniprot id: A8G1G9
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS13290
gene id: 425104:SSED_RS13290
uniprot id: A8FWB5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

425104:SSED RS02595
gene id: 425104:SSED_RS02595
uniprot id: A8FQI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multiheme cytochrome c family.
messages: Binds 8 heme c groups covalently per monomer.
messages: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
messages: Periplasm
messages: Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.

425104:SSED RS08000
gene id: 425104:SSED_RS08000
uniprot id: A8FTI0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

425104:SSED RS19545
gene id: 425104:SSED_RS19545
uniprot id: A8FZS0
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

425104:SSED RS17645
gene id: 425104:SSED_RS17645
uniprot id: A8FYQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

425104:SSED RS03270
gene id: 425104:SSED_RS03270
uniprot id: A8FQX0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS17400
gene id: 425104:SSED_RS17400
uniprot id: A8FYK9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

425104:SSED RS15060
gene id: 425104:SSED_RS15060
uniprot id: A8FXB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

425104:SSED RS02690
gene id: 425104:SSED_RS02690
uniprot id: A8FQK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

425104:SSED RS05375
gene id: 425104:SSED_RS05375
uniprot id: A8FS33
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

425104:SSED RS20600
gene id: 425104:SSED_RS20600
uniprot id: A8G0C8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

425104:SSED RS08445
gene id: 425104:SSED_RS08445
uniprot id: A8FTR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

425104:SSED RS21335
gene id: 425104:SSED_RS21335
uniprot id: A8G0S6
names: Similarity
messages: Belongs to the arginase family.

425104:SSED RS20065
gene id: 425104:SSED_RS20065
uniprot id: A8G022
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS21730
gene id: 425104:SSED_RS21730
uniprot id: A8G0Z7
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS08675
gene id: 425104:SSED_RS08675
uniprot id: A8FTW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS15010
gene id: 425104:SSED_RS15010
uniprot id: A8FXA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS12965
gene id: 425104:SSED_RS12965
uniprot id: A8FW57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

425104:SSED RS00845
gene id: 425104:SSED_RS00845
uniprot id: A8FPK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

425104:SSED RS10295
gene id: 425104:SSED_RS10295
uniprot id: A8FUR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

425104:SSED RS21000
gene id: 425104:SSED_RS21000
uniprot id: A8G0K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

425104:SSED RS22520
gene id: 425104:SSED_RS22520
uniprot id: A8G1F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

425104:SSED RS02090
gene id: 425104:SSED_RS02090
uniprot id: A8FQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

425104:SSED RS20075
gene id: 425104:SSED_RS20075
uniprot id: A8G024
names: Similarity
messages: Belongs to the UPF0111 family.

425104:SSED RS11345
gene id: 425104:SSED_RS11345
uniprot id: A8FVA7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

425104:SSED RS08165
gene id: 425104:SSED_RS08165
uniprot id: A8FTL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

425104:SSED RS09075
gene id: 425104:SSED_RS09075
uniprot id: A8FU45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

425104:SSED RS06120
gene id: 425104:SSED_RS06120
uniprot id: A8FSI1
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

425104:SSED RS21075
gene id: 425104:SSED_RS21075
uniprot id: A8G0M3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS23250
gene id: 425104:SSED_RS23250
uniprot id: A8G1T3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

425104:SSED RS14275
gene id: 425104:SSED_RS14275
uniprot id: A8FWW2
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

425104:SSED RS09730
gene id: 425104:SSED_RS09730
uniprot id: A8FUF7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

425104:SSED RS13735
gene id: 425104:SSED_RS13735
uniprot id: A8FWK1
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

425104:SSED RS03795
gene id: 425104:SSED_RS03795
uniprot id: A8FR76
names: Similarity
messages: Belongs to the BolA/IbaG family.

425104:SSED RS00795
gene id: 425104:SSED_RS00795
uniprot id: A8FPJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS10545
gene id: 425104:SSED_RS10545
uniprot id: A8FUW8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

425104:SSED RS06405
gene id: 425104:SSED_RS06405
uniprot id: A8FSN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

425104:SSED RS21475
gene id: 425104:SSED_RS21475
uniprot id: A8G0V2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS07865
gene id: 425104:SSED_RS07865
uniprot id: A8FTF6
names: Similarity
messages: Belongs to the CdaR family.

425104:SSED RS13640
gene id: 425104:SSED_RS13640
uniprot id: A8FWI1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

425104:SSED RS21700
gene id: 425104:SSED_RS21700
uniprot id: A8G0Z1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

425104:SSED RS21635
gene id: 425104:SSED_RS21635
uniprot id: A8G0X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

425104:SSED RS18320
gene id: 425104:SSED_RS18320
uniprot id: A8FZ29
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

425104:SSED RS21440
gene id: 425104:SSED_RS21440
uniprot id: A8G0U6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

425104:SSED RS09780
gene id: 425104:SSED_RS09780
uniprot id: A8FUG7
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

425104:SSED RS22565
gene id: 425104:SSED_RS22565
uniprot id: A8G1G0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

425104:SSED RS09210
gene id: 425104:SSED_RS09210
uniprot id: A8FU71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

425104:SSED RS01965
gene id: 425104:SSED_RS01965
uniprot id: A8FQ72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

425104:SSED RS01675
gene id: 425104:SSED_RS01675
uniprot id: A8FQ14
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

425104:SSED RS12975
gene id: 425104:SSED_RS12975
uniprot id: A8FW59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

425104:SSED RS03905
gene id: 425104:SSED_RS03905
uniprot id: A8FR97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

425104:SSED RS05935
gene id: 425104:SSED_RS05935
uniprot id: A8FSE4
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS08850
gene id: 425104:SSED_RS08850
uniprot id: A8FU00
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS06360
gene id: 425104:SSED_RS06360
uniprot id: A8FSM5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

425104:SSED RS22200
gene id: 425104:SSED_RS22200
uniprot id: A8G190
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

425104:SSED RS21920
gene id: 425104:SSED_RS21920
uniprot id: A8G135
names: Similarity
messages: Belongs to the peptidase S9C family.

425104:SSED RS04150
gene id: 425104:SSED_RS04150
uniprot id: A8FRE2
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

425104:SSED RS07220
gene id: 425104:SSED_RS07220
uniprot id: A8FT32
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

425104:SSED RS04275
gene id: 425104:SSED_RS04275
uniprot id: A8FRG6
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

425104:SSED RS23480
gene id: 425104:SSED_RS23480
uniprot id: A8G1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

425104:SSED RS12095
gene id: 425104:SSED_RS12095
uniprot id: A8FVP3
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

425104:SSED RS07430
gene id: 425104:SSED_RS07430
uniprot id: A8FT73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

425104:SSED RS04920
gene id: 425104:SSED_RS04920
uniprot id: A8FRU5
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

425104:SSED RS23505
gene id: 425104:SSED_RS23505
uniprot id: A8G1X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

425104:SSED RS17405
gene id: 425104:SSED_RS17405
uniprot id: A8FYL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

425104:SSED RS13005
gene id: 425104:SSED_RS13005
uniprot id: A8FW60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

425104:SSED RS19410
gene id: 425104:SSED_RS19410
uniprot id: A8FZP5
names: Similarity
messages: Belongs to the universal stress protein A family.

425104:SSED RS14390
gene id: 425104:SSED_RS14390
uniprot id: A8FWY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

425104:SSED RS12495
gene id: 425104:SSED_RS12495
uniprot id: A8FVX0
names: Similarity
messages: Belongs to the UPF0047 family.

425104:SSED RS17860
gene id: 425104:SSED_RS17860
uniprot id: A8FYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

425104:SSED RS06645
gene id: 425104:SSED_RS06645
uniprot id: A8FST2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

425104:SSED RS03605
gene id: 425104:SSED_RS03605
uniprot id: A8FR40
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

425104:SSED RS22750
gene id: 425104:SSED_RS22750
uniprot id: A8G1I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

425104:SSED RS23445
gene id: 425104:SSED_RS23445
uniprot id: A8G1W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

425104:SSED RS21990
gene id: 425104:SSED_RS21990
uniprot id: A8G149
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

425104:SSED RS08835
gene id: 425104:SSED_RS08835
uniprot id: A8FTZ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS14945
gene id: 425104:SSED_RS14945
uniprot id: A8FX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS21435
gene id: 425104:SSED_RS21435
uniprot id: A8G0U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS00205
gene id: 425104:SSED_RS00205
uniprot id: A8FP81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

425104:SSED RS09080
gene id: 425104:SSED_RS09080
uniprot id: A8FU46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

425104:SSED RS00925
gene id: 425104:SSED_RS00925
uniprot id: A8FPL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

425104:SSED RS15890
gene id: 425104:SSED_RS15890
uniprot id: A8FXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

425104:SSED RS16420
gene id: 425104:SSED_RS16420
uniprot id: A8FY15
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS00110
gene id: 425104:SSED_RS00110
uniprot id: A8FP62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

425104:SSED RS14710
gene id: 425104:SSED_RS14710
uniprot id: A8FX48
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

425104:SSED RS10365
gene id: 425104:SSED_RS10365
uniprot id: A8FUT1
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

425104:SSED RS04140
gene id: 425104:SSED_RS04140
uniprot id: A8FRE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

425104:SSED RS22570
gene id: 425104:SSED_RS22570
uniprot id: A8G1G1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS01980
gene id: 425104:SSED_RS01980
uniprot id: A8FQ75
names: Similarity
messages: Belongs to the UPF0758 family.

425104:SSED RS16660
gene id: 425104:SSED_RS16660
uniprot id: A8FY63
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS06100
gene id: 425104:SSED_RS06100
uniprot id: A8FSH7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

425104:SSED RS13050
gene id: 425104:SSED_RS13050
uniprot id: A8FW69
names: Similarity
messages: Belongs to the peptidase S41A family.

425104:SSED RS05830
gene id: 425104:SSED_RS05830
uniprot id: A8FSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS22510
gene id: 425104:SSED_RS22510
uniprot id: A8G1E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

425104:SSED RS17635
gene id: 425104:SSED_RS17635
uniprot id: A8FYQ5
names: Similarity
messages: Belongs to the Smp family.

425104:SSED RS10600
gene id: 425104:SSED_RS10600
uniprot id: A8FUX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

425104:SSED RS20505
gene id: 425104:SSED_RS20505
uniprot id: A8G0A9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

425104:SSED RS13355
gene id: 425104:SSED_RS13355
uniprot id: A8FWC7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

425104:SSED RS19225
gene id: 425104:SSED_RS19225
uniprot id: A8FZK8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

425104:SSED RS21275
gene id: 425104:SSED_RS21275
uniprot id: A8G0R4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

425104:SSED RS02805
gene id: 425104:SSED_RS02805
uniprot id: A8FQM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

425104:SSED RS03345
gene id: 425104:SSED_RS03345
uniprot id: A8FQY7
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

425104:SSED RS06095
gene id: 425104:SSED_RS06095
uniprot id: A8FSH6
names: Similarity
messages: Belongs to the UPF0246 family.

425104:SSED RS11315
gene id: 425104:SSED_RS11315
uniprot id: A8FVA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS22765
gene id: 425104:SSED_RS22765
uniprot id: A8G1J0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

425104:SSED RS13010
gene id: 425104:SSED_RS13010
uniprot id: A8FW61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

425104:SSED RS06015
gene id: 425104:SSED_RS06015
uniprot id: A8FSG0
names: Similarity
messages: Belongs to the TrpR family.

425104:SSED RS10555
gene id: 425104:SSED_RS10555
uniprot id: A8FUX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

425104:SSED RS14835
gene id: 425104:SSED_RS14835
uniprot id: A8FX73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS13375
gene id: 425104:SSED_RS13375
uniprot id: A8FWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

425104:SSED RS18735
gene id: 425104:SSED_RS18735
uniprot id: A8FZB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS00145
gene id: 425104:SSED_RS00145
uniprot id: A8FP69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell inner membrane

425104:SSED RS07240
gene id: 425104:SSED_RS07240
uniprot id: A8FT36
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS07460
gene id: 425104:SSED_RS07460
uniprot id: A8FT78
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

425104:SSED RS11090
gene id: 425104:SSED_RS11090
uniprot id: A8FV58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

425104:SSED RS23225
gene id: 425104:SSED_RS23225
uniprot id: A8G1S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

425104:SSED RS08895
gene id: 425104:SSED_RS08895
uniprot id: A8FU09
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

425104:SSED RS16130
gene id: 425104:SSED_RS16130
uniprot id: A8FXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

425104:SSED RS08500
gene id: 425104:SSED_RS08500
uniprot id: A8FTT0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

425104:SSED RS08005
gene id: 425104:SSED_RS08005
uniprot id: A8FTI1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

425104:SSED RS06885
gene id: 425104:SSED_RS06885
uniprot id: A8FSW7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

425104:SSED RS03750
gene id: 425104:SSED_RS03750
uniprot id: A8FR67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

425104:SSED RS16070
gene id: 425104:SSED_RS16070
uniprot id: A8FXU8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

425104:SSED RS06135
gene id: 425104:SSED_RS06135
uniprot id: A8FSI4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS06090
gene id: 425104:SSED_RS06090
uniprot id: A8FSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS00670
gene id: 425104:SSED_RS00670
uniprot id: A8FPG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

425104:SSED RS23120
gene id: 425104:SSED_RS23120
uniprot id: A8G1Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

425104:SSED RS05820
gene id: 425104:SSED_RS05820
uniprot id: A8FSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

425104:SSED RS04400
gene id: 425104:SSED_RS04400
uniprot id: A8FRJ1
names: Similarity
messages: Belongs to the SufE family.

425104:SSED RS18400
gene id: 425104:SSED_RS18400
uniprot id: A8FZ44
names: Similarity
messages: Belongs to the GST superfamily.

425104:SSED RS21310
gene id: 425104:SSED_RS21310
uniprot id: A8G0S1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

425104:SSED RS07625
gene id: 425104:SSED_RS07625
uniprot id: A8FTB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

425104:SSED RS03170
gene id: 425104:SSED_RS03170
uniprot id: A8FQU9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

425104:SSED RS16685
gene id: 425104:SSED_RS16685
uniprot id: A8FY68
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS01175
gene id: 425104:SSED_RS01175
uniprot id: A8FPS0
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

425104:SSED RS04760
gene id: 425104:SSED_RS04760
uniprot id: A8FRR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane

425104:SSED RS01230
gene id: 425104:SSED_RS01230
uniprot id: A8FPT1
names: Subcellular Location Annotation
messages: Periplasm

425104:SSED RS05810
gene id: 425104:SSED_RS05810
uniprot id: A8FSB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

425104:SSED RS04940
gene id: 425104:SSED_RS04940
uniprot id: A8FRU9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS14400
gene id: 425104:SSED_RS14400
uniprot id: A8FWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS08485
gene id: 425104:SSED_RS08485
uniprot id: A8FTS7
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22165
gene id: 425104:SSED_RS22165
uniprot id: A8G183
names: Similarity
messages: Belongs to the UPF0102 family.

425104:SSED RS10445
gene id: 425104:SSED_RS10445
uniprot id: A8FUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

425104:SSED RS05755
gene id: 425104:SSED_RS05755
uniprot id: A8FSA8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

425104:SSED RS16000
gene id: 425104:SSED_RS16000
uniprot id: A8FXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

425104:SSED RS00560
gene id: 425104:SSED_RS00560
uniprot id: A8FPE6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

425104:SSED RS00570
gene id: 425104:SSED_RS00570
uniprot id: A8FPE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

425104:SSED RS13950
gene id: 425104:SSED_RS13950
uniprot id: A8FWP4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

425104:SSED RS19360
gene id: 425104:SSED_RS19360
uniprot id: A8FZN6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS03855
gene id: 425104:SSED_RS03855
uniprot id: A8FR88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

425104:SSED RS04610
gene id: 425104:SSED_RS04610
uniprot id: A8FRN3
names: Similarity
messages: Belongs to the RecJ family.

425104:SSED RS04750
gene id: 425104:SSED_RS04750
uniprot id: A8FRR1
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

425104:SSED RS18305
gene id: 425104:SSED_RS18305
uniprot id: A8FZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

425104:SSED RS06655
gene id: 425104:SSED_RS06655
uniprot id: A8FST4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

425104:SSED RS08270
gene id: 425104:SSED_RS08270
uniprot id: A8FTN3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS01580
gene id: 425104:SSED_RS01580
uniprot id: A8FPZ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS17920
gene id: 425104:SSED_RS17920
uniprot id: A8FYW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS05705
gene id: 425104:SSED_RS05705
uniprot id: A8FS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS11845
gene id: 425104:SSED_RS11845
uniprot id: A8FVJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS02440
gene id: 425104:SSED_RS02440
uniprot id: A8FQF3
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS09795
gene id: 425104:SSED_RS09795
uniprot id: A8FUH0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

425104:SSED RS14555
gene id: 425104:SSED_RS14555
uniprot id: A8FX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

425104:SSED RS22285
gene id: 425104:SSED_RS22285
uniprot id: A8G1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

425104:SSED RS22530
gene id: 425104:SSED_RS22530
uniprot id: A8G1F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

425104:SSED RS05675
gene id: 425104:SSED_RS05675
uniprot id: A8FS92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS09095
gene id: 425104:SSED_RS09095
uniprot id: A8FU49
names: Similarity
messages: Belongs to the proline racemase family.

425104:SSED RS07225
gene id: 425104:SSED_RS07225
uniprot id: A8FT33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

425104:SSED RS03590
gene id: 425104:SSED_RS03590
uniprot id: A8FR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS14935
gene id: 425104:SSED_RS14935
uniprot id: A8FX93
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS14375
gene id: 425104:SSED_RS14375
uniprot id: A8FWY1
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

425104:SSED RS21970
gene id: 425104:SSED_RS21970
uniprot id: A8G145
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

425104:SSED RS22665
gene id: 425104:SSED_RS22665
uniprot id: A8G1H0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

425104:SSED RS10540
gene id: 425104:SSED_RS10540
uniprot id: A8FUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

425104:SSED RS06220
gene id: 425104:SSED_RS06220
uniprot id: A8FSK1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

425104:SSED RS19660
gene id: 425104:SSED_RS19660
uniprot id: A8FZU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

425104:SSED RS16825
gene id: 425104:SSED_RS16825
uniprot id: A8FY95
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS13630
gene id: 425104:SSED_RS13630
uniprot id: A8FWH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

425104:SSED RS17895
gene id: 425104:SSED_RS17895
uniprot id: A8FYV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

425104:SSED RS00270
gene id: 425104:SSED_RS00270
uniprot id: A8FP90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

425104:SSED RS13425
gene id: 425104:SSED_RS13425
uniprot id: A8FWE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

425104:SSED RS04325
gene id: 425104:SSED_RS04325
uniprot id: A8FRH6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

425104:SSED RS23475
gene id: 425104:SSED_RS23475
uniprot id: A8G1X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

425104:SSED RS05270
gene id: 425104:SSED_RS05270
uniprot id: A8FS13
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS05470
gene id: 425104:SSED_RS05470
uniprot id: A8FS52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS13470
gene id: 425104:SSED_RS13470
uniprot id: A8FWE8
names: Similarity
messages: Belongs to the pirin family.

425104:SSED RS20800
gene id: 425104:SSED_RS20800
uniprot id: A8G0G8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

425104:SSED RS04900
gene id: 425104:SSED_RS04900
uniprot id: A8FRU1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

425104:SSED RS12190
gene id: 425104:SSED_RS12190
uniprot id: A8FVR1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS05775
gene id: 425104:SSED_RS05775
uniprot id: A8FSB2
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

425104:SSED RS21795
gene id: 425104:SSED_RS21795
uniprot id: A8G110
names: Subcellular Location Annotation
messages: Periplasm

425104:SSED RS07390
gene id: 425104:SSED_RS07390
uniprot id: A8FT65
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

425104:SSED RS19380
gene id: 425104:SSED_RS19380
uniprot id: A8FZN9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

425104:SSED RS21505
gene id: 425104:SSED_RS21505
uniprot id: A8G0V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

425104:SSED RS13980
gene id: 425104:SSED_RS13980
uniprot id: A8FWQ0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

425104:SSED RS01205
gene id: 425104:SSED_RS01205
uniprot id: A8FPS6
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

425104:SSED RS15610
gene id: 425104:SSED_RS15610
uniprot id: A8FXK7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

425104:SSED RS04505
gene id: 425104:SSED_RS04505
uniprot id: A8FRL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

425104:SSED RS17340
gene id: 425104:SSED_RS17340
uniprot id: A8FYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS21410
gene id: 425104:SSED_RS21410
uniprot id: A8G0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

425104:SSED RS23685
gene id: 425104:SSED_RS23685
uniprot id: A8FX99
names: Subcellular Location Annotation
messages: Cell inner membrane

425104:SSED RS03180
gene id: 425104:SSED_RS03180
uniprot id: A8FQV1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

425104:SSED RS20210
gene id: 425104:SSED_RS20210
uniprot id: A8G051
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

425104:SSED RS08475
gene id: 425104:SSED_RS08475
uniprot id: A8FTS5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

425104:SSED RS14650
gene id: 425104:SSED_RS14650
uniprot id: A8FX36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

425104:SSED RS06080
gene id: 425104:SSED_RS06080
uniprot id: A8FSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

425104:SSED RS17600
gene id: 425104:SSED_RS17600
uniprot id: A8FYP9
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

425104:SSED RS10905
gene id: 425104:SSED_RS10905
uniprot id: A8FV29
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS23455
gene id: 425104:SSED_RS23455
uniprot id: A8G1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

425104:SSED RS02640
gene id: 425104:SSED_RS02640
uniprot id: A8FQJ2
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS20350
gene id: 425104:SSED_RS20350
uniprot id: A8G078
names: Similarity
messages: Belongs to the peptidase M17 family.

425104:SSED RS20665
gene id: 425104:SSED_RS20665
uniprot id: A8G0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Periplasm

425104:SSED RS12385
gene id: 425104:SSED_RS12385
uniprot id: A8FVV0
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00835
gene id: 425104:SSED_RS00835
uniprot id: A8FPK1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS09735
gene id: 425104:SSED_RS09735
uniprot id: A8FUF8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

425104:SSED RS00395
gene id: 425104:SSED_RS00395
uniprot id: A8FPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

425104:SSED RS05980
gene id: 425104:SSED_RS05980
uniprot id: A8FSF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

425104:SSED RS21345
gene id: 425104:SSED_RS21345
uniprot id: A8G0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

425104:SSED RS06625
gene id: 425104:SSED_RS06625
uniprot id: A8FSS8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

425104:SSED RS16860
gene id: 425104:SSED_RS16860
uniprot id: A8FYA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS21300
gene id: 425104:SSED_RS21300
uniprot id: A8G0R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

425104:SSED RS10700
gene id: 425104:SSED_RS10700
uniprot id: A8FUY8
names: Similarity
messages: Belongs to the UPF0381 family.

425104:SSED RS14900
gene id: 425104:SSED_RS14900
uniprot id: A8FX85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

425104:SSED RS10275
gene id: 425104:SSED_RS10275
uniprot id: A8FUR5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

425104:SSED RS08160
gene id: 425104:SSED_RS08160
uniprot id: A8FTL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

425104:SSED RS08975
gene id: 425104:SSED_RS08975
uniprot id: A8FU26
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

425104:SSED RS07640
gene id: 425104:SSED_RS07640
uniprot id: A8FTB3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

425104:SSED RS20510
gene id: 425104:SSED_RS20510
uniprot id: A8G0B0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

425104:SSED RS16365
gene id: 425104:SSED_RS16365
uniprot id: A8FY05
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

425104:SSED RS22170
gene id: 425104:SSED_RS22170
uniprot id: A8G184
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

425104:SSED RS04120
gene id: 425104:SSED_RS04120
uniprot id: A8FRD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

425104:SSED RS04865
gene id: 425104:SSED_RS04865
uniprot id: A8FRT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS19920
gene id: 425104:SSED_RS19920
uniprot id: A8FZZ3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

425104:SSED RS01195
gene id: 425104:SSED_RS01195
uniprot id: A8FPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

425104:SSED RS07660
gene id: 425104:SSED_RS07660
uniprot id: A8FTB7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

425104:SSED RS03125
gene id: 425104:SSED_RS03125
uniprot id: A8FQU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS04930
gene id: 425104:SSED_RS04930
uniprot id: A8FRU7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

425104:SSED RS10450
gene id: 425104:SSED_RS10450
uniprot id: A8FUU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

425104:SSED RS22235
gene id: 425104:SSED_RS22235
uniprot id: A8G197
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

425104:SSED RS18610
gene id: 425104:SSED_RS18610
uniprot id: A8FZ86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

425104:SSED RS13875
gene id: 425104:SSED_RS13875
uniprot id: A8FWM9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

425104:SSED RS03775
gene id: 425104:SSED_RS03775
uniprot id: A8FR72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

425104:SSED RS09190
gene id: 425104:SSED_RS09190
uniprot id: A8FU67
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS05760
gene id: 425104:SSED_RS05760
uniprot id: A8FSA9
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

425104:SSED RS22420
gene id: 425104:SSED_RS22420
uniprot id: A8G1D1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

425104:SSED RS17360
gene id: 425104:SSED_RS17360
uniprot id: A8FYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

425104:SSED RS22305
gene id: 425104:SSED_RS22305
uniprot id: A8G1B1
names: Similarity
messages: Belongs to the CinA family.

425104:SSED RS22850
gene id: 425104:SSED_RS22850
uniprot id: A8G1K5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS04405
gene id: 425104:SSED_RS04405
uniprot id: A8FRJ2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

425104:SSED RS01155
gene id: 425104:SSED_RS01155
uniprot id: A8FPR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

425104:SSED RS14155
gene id: 425104:SSED_RS14155
uniprot id: A8FWT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

425104:SSED RS13615
gene id: 425104:SSED_RS13615
uniprot id: A8FWH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS22855
gene id: 425104:SSED_RS22855
uniprot id: A8G1K6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

425104:SSED RS05715
gene id: 425104:SSED_RS05715
uniprot id: A8FSA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

425104:SSED RS22395
gene id: 425104:SSED_RS22395
uniprot id: A8G1C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

425104:SSED RS18315
gene id: 425104:SSED_RS18315
uniprot id: A8FZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

425104:SSED RS22830
gene id: 425104:SSED_RS22830
uniprot id: A8G1K1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

425104:SSED RS12395
gene id: 425104:SSED_RS12395
uniprot id: A8FVV2
names: Similarity
messages: Belongs to the GSP E family.

425104:SSED RS08325
gene id: 425104:SSED_RS08325
uniprot id: A8FTP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS17760
gene id: 425104:SSED_RS17760
uniprot id: A8FYS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

425104:SSED RS07275
gene id: 425104:SSED_RS07275
uniprot id: A8FT42
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

425104:SSED RS16915
gene id: 425104:SSED_RS16915
uniprot id: A8FYB3
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Part of an electron transfer system.

425104:SSED RS14995
gene id: 425104:SSED_RS14995
uniprot id: A8FXA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

425104:SSED RS02530
gene id: 425104:SSED_RS02530
uniprot id: A8FQH0
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

425104:SSED RS16570
gene id: 425104:SSED_RS16570
uniprot id: A8FY45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

425104:SSED RS00335
gene id: 425104:SSED_RS00335
uniprot id: A8FPA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

425104:SSED RS23295
gene id: 425104:SSED_RS23295
uniprot id: A8G1U2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS05595
gene id: 425104:SSED_RS05595
uniprot id: A8FS76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS08440
gene id: 425104:SSED_RS08440
uniprot id: A8FTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

425104:SSED RS04090
gene id: 425104:SSED_RS04090
uniprot id: A8FRD0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS13850
gene id: 425104:SSED_RS13850
uniprot id: A8FWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS22970
gene id: 425104:SSED_RS22970
uniprot id: A8G1N0
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

425104:SSED RS01970
gene id: 425104:SSED_RS01970
uniprot id: A8FQ73
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

425104:SSED RS07020
gene id: 425104:SSED_RS07020
uniprot id: A8FSZ4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

425104:SSED RS11170
gene id: 425104:SSED_RS11170
uniprot id: A8FV73
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS05905
gene id: 425104:SSED_RS05905
uniprot id: A8FSD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

425104:SSED RS16005
gene id: 425104:SSED_RS16005
uniprot id: A8FXT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

425104:SSED RS01380
gene id: 425104:SSED_RS01380
uniprot id: A8FPW2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS16830
gene id: 425104:SSED_RS16830
uniprot id: A8FY96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS18060
gene id: 425104:SSED_RS18060
uniprot id: A8FYZ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

425104:SSED RS23750
gene id: 425104:SSED_RS23750
uniprot id: A8FZ98
names: Similarity
messages: Belongs to the peptidase A1 family.

425104:SSED RS18070
gene id: 425104:SSED_RS18070
uniprot id: A8FYZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

425104:SSED RS03710
gene id: 425104:SSED_RS03710
uniprot id: A8FR59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS22265
gene id: 425104:SSED_RS22265
uniprot id: A8G1A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

425104:SSED RS00070
gene id: 425104:SSED_RS00070
uniprot id: A8FP54
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

425104:SSED RS00190
gene id: 425104:SSED_RS00190
uniprot id: A8FP78
names: Similarity
messages: Belongs to the Smg family.

425104:SSED RS10325
gene id: 425104:SSED_RS10325
uniprot id: A8FUS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

425104:SSED RS16755
gene id: 425104:SSED_RS16755
uniprot id: A8FY81
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

425104:SSED RS01390
gene id: 425104:SSED_RS01390
uniprot id: A8FPW4
names: Subcellular Location Annotation
messages: Periplasm

425104:SSED RS15470
gene id: 425104:SSED_RS15470
uniprot id: A8FXH9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

425104:SSED RS19560
gene id: 425104:SSED_RS19560
uniprot id: A8FZS3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS09915
gene id: 425104:SSED_RS09915
uniprot id: A8FUJ6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

425104:SSED RS09375
gene id: 425104:SSED_RS09375
uniprot id: A8FU98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

425104:SSED RS04700
gene id: 425104:SSED_RS04700
uniprot id: A8FRQ1
names: Similarity
messages: Belongs to the peptidase M1 family.

425104:SSED RS14490
gene id: 425104:SSED_RS14490
uniprot id: A8FX03
names: Subcellular Location Annotation
messages: Periplasm

425104:SSED RS21060
gene id: 425104:SSED_RS21060
uniprot id: A8G0M0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

425104:SSED RS15680
gene id: 425104:SSED_RS15680
uniprot id: A8FXM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

425104:SSED RS07400
gene id: 425104:SSED_RS07400
uniprot id: A8FT67
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

425104:SSED RS11130
gene id: 425104:SSED_RS11130
uniprot id: A8FV66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

425104:SSED RS01590
gene id: 425104:SSED_RS01590
uniprot id: A8FPZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

425104:SSED RS03120
gene id: 425104:SSED_RS03120
uniprot id: A8FQT9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

425104:SSED RS23330
gene id: 425104:SSED_RS23330
uniprot id: A8G1U9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

425104:SSED RS14135
gene id: 425104:SSED_RS14135
uniprot id: A8FWT1
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

425104:SSED RS04105
gene id: 425104:SSED_RS04105
uniprot id: A8FRD3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

425104:SSED RS09945
gene id: 425104:SSED_RS09945
uniprot id: A8FUK2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

425104:SSED RS00215
gene id: 425104:SSED_RS00215
uniprot id: A8FP83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

425104:SSED RS21010
gene id: 425104:SSED_RS21010
uniprot id: A8G0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

425104:SSED RS22505
gene id: 425104:SSED_RS22505
uniprot id: A8G1E8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

425104:SSED RS19930
gene id: 425104:SSED_RS19930
uniprot id: A8FZZ5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

425104:SSED RS13235
gene id: 425104:SSED_RS13235
uniprot id: A8FWA4
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

425104:SSED RS06410
gene id: 425104:SSED_RS06410
uniprot id: A8FSN5
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

425104:SSED RS12565
gene id: 425104:SSED_RS12565
uniprot id: A8FVY5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

425104:SSED RS12830
gene id: 425104:SSED_RS12830
uniprot id: A8FW37
names: Similarity
messages: Belongs to the YkuD family.

425104:SSED RS08355
gene id: 425104:SSED_RS08355
uniprot id: A8FTP9
names: Similarity
messages: Belongs to the peptidase S8 family.

425104:SSED RS19125
gene id: 425104:SSED_RS19125
uniprot id: A8FZI8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

425104:SSED RS05555
gene id: 425104:SSED_RS05555
uniprot id: A8FS68
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

425104:SSED RS12255
gene id: 425104:SSED_RS12255
uniprot id: A8FVS4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

425104:SSED RS18645
gene id: 425104:SSED_RS18645
uniprot id: A8FZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

425104:SSED RS20995
gene id: 425104:SSED_RS20995
uniprot id: A8G0K7
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22425
gene id: 425104:SSED_RS22425
uniprot id: A8G1D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

425104:SSED RS15790
gene id: 425104:SSED_RS15790
uniprot id: A8FXP2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

425104:SSED RS16965
gene id: 425104:SSED_RS16965
uniprot id: A8FYC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS23065
gene id: 425104:SSED_RS23065
uniprot id: A8G1P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

425104:SSED RS08235
gene id: 425104:SSED_RS08235
uniprot id: A8FTM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

425104:SSED RS21550
gene id: 425104:SSED_RS21550
uniprot id: A8G0W7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

425104:SSED RS22055
gene id: 425104:SSED_RS22055
uniprot id: A8G163
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS22015
gene id: 425104:SSED_RS22015
uniprot id: A8G154
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

425104:SSED RS02605
gene id: 425104:SSED_RS02605
uniprot id: A8FQI5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS09845
gene id: 425104:SSED_RS09845
uniprot id: A8FUI0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

425104:SSED RS17275
gene id: 425104:SSED_RS17275
uniprot id: A8FYI4
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

425104:SSED RS05655
gene id: 425104:SSED_RS05655
uniprot id: A8FS88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS15500
gene id: 425104:SSED_RS15500
uniprot id: A8FXI5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

425104:SSED RS20735
gene id: 425104:SSED_RS20735
uniprot id: A8G0F5
names: Similarity
messages: Belongs to the alkaline phosphatase family.

425104:SSED RS12730
gene id: 425104:SSED_RS12730
uniprot id: A8FW17
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS04730
gene id: 425104:SSED_RS04730
uniprot id: A8FRQ7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

425104:SSED RS22515
gene id: 425104:SSED_RS22515
uniprot id: A8G1F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

425104:SSED RS20650
gene id: 425104:SSED_RS20650
uniprot id: A8G0D8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

425104:SSED RS22770
gene id: 425104:SSED_RS22770
uniprot id: A8G1J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

425104:SSED RS14990
gene id: 425104:SSED_RS14990
uniprot id: A8FXA4
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

425104:SSED RS02955
gene id: 425104:SSED_RS02955
uniprot id: A8FQQ5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

425104:SSED RS23485
gene id: 425104:SSED_RS23485
uniprot id: A8G1X2
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00900
gene id: 425104:SSED_RS00900
uniprot id: A8FPL4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

425104:SSED RS10045
gene id: 425104:SSED_RS10045
uniprot id: A8FUM3
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

425104:SSED RS04910
gene id: 425104:SSED_RS04910
uniprot id: A8FRU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

425104:SSED RS14195
gene id: 425104:SSED_RS14195
uniprot id: A8FWU3
names: Similarity
messages: Belongs to the glyoxalase I family.

425104:SSED RS16900
gene id: 425104:SSED_RS16900
uniprot id: A8FYB0
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS20120
gene id: 425104:SSED_RS20120
uniprot id: A8G033
names: Similarity
messages: Belongs to the DEAD box helicase family.

425104:SSED RS08900
gene id: 425104:SSED_RS08900
uniprot id: A8FU10
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22450
gene id: 425104:SSED_RS22450
uniprot id: A8G1D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

425104:SSED RS07435
gene id: 425104:SSED_RS07435
uniprot id: A8FT74
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

425104:SSED RS04280
gene id: 425104:SSED_RS04280
uniprot id: A8FRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

425104:SSED RS20815
gene id: 425104:SSED_RS20815
uniprot id: A8G0H1
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

425104:SSED RS11095
gene id: 425104:SSED_RS11095
uniprot id: A8FV59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

425104:SSED RS04775
gene id: 425104:SSED_RS04775
uniprot id: A8FRR6
names: Similarity
messages: Belongs to the UPF0231 family.

425104:SSED RS16455
gene id: 425104:SSED_RS16455
uniprot id: A8FY22
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS16090
gene id: 425104:SSED_RS16090
uniprot id: A8FXV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

425104:SSED RS07150
gene id: 425104:SSED_RS07150
uniprot id: A8FT19
names: Subcellular Location Annotation
messages: Cell inner membrane

425104:SSED RS12950
gene id: 425104:SSED_RS12950
uniprot id: A8FW53
names: Similarity
messages: Belongs to the peptidase S16 family.

425104:SSED RS00830
gene id: 425104:SSED_RS00830
uniprot id: A8FPK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

425104:SSED RS09415
gene id: 425104:SSED_RS09415
uniprot id: A8FUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

425104:SSED RS17900
gene id: 425104:SSED_RS17900
uniprot id: A8FYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS10060
gene id: 425104:SSED_RS10060
uniprot id: A8FUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

425104:SSED RS14815
gene id: 425104:SSED_RS14815
uniprot id: A8FX69
names: Similarity
messages: Belongs to the acylphosphatase family.

425104:SSED RS09880
gene id: 425104:SSED_RS09880
uniprot id: A8FUI9
names: Similarity
messages: Belongs to the HupF/HypC family.

425104:SSED RS18895
gene id: 425104:SSED_RS18895
uniprot id: A8FZE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

425104:SSED RS17710
gene id: 425104:SSED_RS17710
uniprot id: A8FYS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

425104:SSED RS05945
gene id: 425104:SSED_RS05945
uniprot id: A8FSE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

425104:SSED RS04740
gene id: 425104:SSED_RS04740
uniprot id: A8FRQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnE family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

425104:SSED RS17115
gene id: 425104:SSED_RS17115
uniprot id: A8FYF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

425104:SSED RS20415
gene id: 425104:SSED_RS20415
uniprot id: A8G091
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

425104:SSED RS10000
gene id: 425104:SSED_RS10000
uniprot id: A8FUL4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

425104:SSED RS15875
gene id: 425104:SSED_RS15875
uniprot id: A8FXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

425104:SSED RS18765
gene id: 425104:SSED_RS18765
uniprot id: A8FZB6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS14860
gene id: 425104:SSED_RS14860
uniprot id: A8FX77
names: Similarity
messages: Belongs to the intimin/invasin family.

425104:SSED RS18955
gene id: 425104:SSED_RS18955
uniprot id: A8FZF4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

425104:SSED RS07180
gene id: 425104:SSED_RS07180
uniprot id: A8FT25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

425104:SSED RS20835
gene id: 425104:SSED_RS20835
uniprot id: A8G0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

425104:SSED RS09725
gene id: 425104:SSED_RS09725
uniprot id: A8FUF6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

425104:SSED RS17380
gene id: 425104:SSED_RS17380
uniprot id: A8FYK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

425104:SSED RS11365
gene id: 425104:SSED_RS11365
uniprot id: A8FVB1
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

425104:SSED RS05750
gene id: 425104:SSED_RS05750
uniprot id: A8FSA7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

425104:SSED RS10385
gene id: 425104:SSED_RS10385
uniprot id: A8FUT5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

425104:SSED RS12715
gene id: 425104:SSED_RS12715
uniprot id: A8FW14
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS03900
gene id: 425104:SSED_RS03900
uniprot id: A8FR96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

425104:SSED RS16050
gene id: 425104:SSED_RS16050
uniprot id: A8FXU4
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS19205
gene id: 425104:SSED_RS19205
uniprot id: A8FZK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

425104:SSED RS22030
gene id: 425104:SSED_RS22030
uniprot id: A8G158
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

425104:SSED RS01635
gene id: 425104:SSED_RS01635
uniprot id: A8FQ06
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22290
gene id: 425104:SSED_RS22290
uniprot id: A8G1A8
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

425104:SSED RS02035
gene id: 425104:SSED_RS02035
uniprot id: A8FQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

425104:SSED RS15670
gene id: 425104:SSED_RS15670
uniprot id: A8FXL9
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

425104:SSED RS07745
gene id: 425104:SSED_RS07745
uniprot id: A8FTD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS16195
gene id: 425104:SSED_RS16195
uniprot id: A8FXX3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

425104:SSED RS01705
gene id: 425104:SSED_RS01705
uniprot id: A8FQ20
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00265
gene id: 425104:SSED_RS00265
uniprot id: A8FP89
names: Similarity
messages: Belongs to the MotB family.

425104:SSED RS18720
gene id: 425104:SSED_RS18720
uniprot id: A8FZA7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS14855
gene id: 425104:SSED_RS14855
uniprot id: A8FX76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

425104:SSED RS05215
gene id: 425104:SSED_RS05215
uniprot id: A8FS02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

425104:SSED RS08705
gene id: 425104:SSED_RS08705
uniprot id: A8FTX1
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

425104:SSED RS03835
gene id: 425104:SSED_RS03835
uniprot id: A8FR84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

425104:SSED RS05845
gene id: 425104:SSED_RS05845
uniprot id: A8FSC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS21070
gene id: 425104:SSED_RS21070
uniprot id: A8G0M2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

425104:SSED RS12220
gene id: 425104:SSED_RS12220
uniprot id: A8FVR7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

425104:SSED RS11265
gene id: 425104:SSED_RS11265
uniprot id: A8FV91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

425104:SSED RS04350
gene id: 425104:SSED_RS04350
uniprot id: A8FRI1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

425104:SSED RS01420
gene id: 425104:SSED_RS01420
uniprot id: A8FPX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

425104:SSED RS17915
gene id: 425104:SSED_RS17915
uniprot id: A8FYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS07570
gene id: 425104:SSED_RS07570
uniprot id: A8FT99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

425104:SSED RS22600
gene id: 425104:SSED_RS22600
uniprot id: A8G1G3
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

425104:SSED RS12375
gene id: 425104:SSED_RS12375
uniprot id: A8FVU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS13495
gene id: 425104:SSED_RS13495
uniprot id: A8FWF2
names: Similarity
messages: Belongs to the AOR/FOR family.

425104:SSED RS08630
gene id: 425104:SSED_RS08630
uniprot id: A8FTV6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

425104:SSED RS02105
gene id: 425104:SSED_RS02105
uniprot id: A8FQA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

425104:SSED RS08790
gene id: 425104:SSED_RS08790
uniprot id: A8FTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

425104:SSED RS02620
gene id: 425104:SSED_RS02620
uniprot id: A8FQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

425104:SSED RS21445
gene id: 425104:SSED_RS21445
uniprot id: A8G0U7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: The fumarate reductase enzyme complex is required for fumarate respiration. This subunit anchors the complex in the membrane and binds a diheme cytochrome b.

425104:SSED RS17875
gene id: 425104:SSED_RS17875
uniprot id: A8FYV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

425104:SSED RS06160
gene id: 425104:SSED_RS06160
uniprot id: A8FSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

425104:SSED RS13720
gene id: 425104:SSED_RS13720
uniprot id: A8FWJ8
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS05815
gene id: 425104:SSED_RS05815
uniprot id: A8FSC0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

425104:SSED RS06635
gene id: 425104:SSED_RS06635
uniprot id: A8FST0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

425104:SSED RS05630
gene id: 425104:SSED_RS05630
uniprot id: A8FS83
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

425104:SSED RS20965
gene id: 425104:SSED_RS20965
uniprot id: A8G0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

425104:SSED RS02930
gene id: 425104:SSED_RS02930
uniprot id: A8FQQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

425104:SSED RS10490
gene id: 425104:SSED_RS10490
uniprot id: A8FUV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS15445
gene id: 425104:SSED_RS15445
uniprot id: A8FXH5
names: Subcellular Location Annotation
messages: Cell inner membrane

425104:SSED RS16510
gene id: 425104:SSED_RS16510
uniprot id: A8FY33
names: Similarity
messages: Belongs to the skp family.

425104:SSED RS18825
gene id: 425104:SSED_RS18825
uniprot id: A8FZC8
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.

425104:SSED RS02790
gene id: 425104:SSED_RS02790
uniprot id: A8FQM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS06295
gene id: 425104:SSED_RS06295
uniprot id: A8FSL2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS02460
gene id: 425104:SSED_RS02460
uniprot id: A8FQF6
names: Similarity
messages: Belongs to the RutC family.

425104:SSED RS13215
gene id: 425104:SSED_RS13215
uniprot id: A8FWA0
names: Similarity
messages: Belongs to the UPF0260 family.

425104:SSED RS11305
gene id: 425104:SSED_RS11305
uniprot id: A8FV99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

425104:SSED RS09785
gene id: 425104:SSED_RS09785
uniprot id: A8FUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

425104:SSED RS11125
gene id: 425104:SSED_RS11125
uniprot id: A8FV65
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

425104:SSED RS03825
gene id: 425104:SSED_RS03825
uniprot id: A8FR82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

425104:SSED RS12065
gene id: 425104:SSED_RS12065
uniprot id: A8FVN7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

425104:SSED RS06530
gene id: 425104:SSED_RS06530
uniprot id: A8FSQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS02020
gene id: 425104:SSED_RS02020
uniprot id: A8FQ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

425104:SSED RS16700
gene id: 425104:SSED_RS16700
uniprot id: A8FY71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

425104:SSED RS23315
gene id: 425104:SSED_RS23315
uniprot id: A8G1U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

425104:SSED RS01565
gene id: 425104:SSED_RS01565
uniprot id: A8FPZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

425104:SSED RS21575
gene id: 425104:SSED_RS21575
uniprot id: A8G0X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

425104:SSED RS22435
gene id: 425104:SSED_RS22435
uniprot id: A8G1D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

425104:SSED RS01010
gene id: 425104:SSED_RS01010
uniprot id: A8FPN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

425104:SSED RS12200
gene id: 425104:SSED_RS12200
uniprot id: A8FVR3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

425104:SSED RS06130
gene id: 425104:SSED_RS06130
uniprot id: A8FSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

425104:SSED RS12725
gene id: 425104:SSED_RS12725
uniprot id: A8FW16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

425104:SSED RS22390
gene id: 425104:SSED_RS22390
uniprot id: A8G1C5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

425104:SSED RS09910
gene id: 425104:SSED_RS09910
uniprot id: A8FUJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

425104:SSED RS15050
gene id: 425104:SSED_RS15050
uniprot id: A8FXB6
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS05410
gene id: 425104:SSED_RS05410
uniprot id: A8FS41
names: Similarity
messages: Belongs to the Gfa family.

425104:SSED RS07530
gene id: 425104:SSED_RS07530
uniprot id: A8FT92
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

425104:SSED RS04915
gene id: 425104:SSED_RS04915
uniprot id: A8FRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS04945
gene id: 425104:SSED_RS04945
uniprot id: A8FRV0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

425104:SSED RS19070
gene id: 425104:SSED_RS19070
uniprot id: A8FZH7
names: Similarity
messages: Belongs to the UPF0751 family.

425104:SSED RS01075
gene id: 425104:SSED_RS01075
uniprot id: A8FPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

425104:SSED RS06770
gene id: 425104:SSED_RS06770
uniprot id: A8FSV6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

425104:SSED RS07295
gene id: 425104:SSED_RS07295
uniprot id: A8FT46
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

425104:SSED RS04875
gene id: 425104:SSED_RS04875
uniprot id: A8FRT6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

425104:SSED RS13765
gene id: 425104:SSED_RS13765
uniprot id: A8FWK7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

425104:SSED RS05970
gene id: 425104:SSED_RS05970
uniprot id: A8FSF1
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

425104:SSED RS14890
gene id: 425104:SSED_RS14890
uniprot id: A8FX83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

425104:SSED RS15285
gene id: 425104:SSED_RS15285
uniprot id: A8FXE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

425104:SSED RS06450
gene id: 425104:SSED_RS06450
uniprot id: A8FSP3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS15885
gene id: 425104:SSED_RS15885
uniprot id: A8FXR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS04185
gene id: 425104:SSED_RS04185
uniprot id: A8FRE9
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

425104:SSED RS02470
gene id: 425104:SSED_RS02470
uniprot id: A8FQF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

425104:SSED RS02120
gene id: 425104:SSED_RS02120
uniprot id: A8FQA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

425104:SSED RS06265
gene id: 425104:SSED_RS06265
uniprot id: A8FSK6
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

425104:SSED RS18750
gene id: 425104:SSED_RS18750
uniprot id: A8FZB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS17655
gene id: 425104:SSED_RS17655
uniprot id: A8FYQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

425104:SSED RS05180
gene id: 425104:SSED_RS05180
uniprot id: A8FRZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

425104:SSED RS07585
gene id: 425104:SSED_RS07585
uniprot id: A8FTA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

425104:SSED RS20715
gene id: 425104:SSED_RS20715
uniprot id: A8G0F1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

425104:SSED RS23470
gene id: 425104:SSED_RS23470
uniprot id: A8G1W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

425104:SSED RS16310
gene id: 425104:SSED_RS16310
uniprot id: A8FXZ5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS10335
gene id: 425104:SSED_RS10335
uniprot id: A8FUS7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS18815
gene id: 425104:SSED_RS18815
uniprot id: A8FZC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

425104:SSED RS14055
gene id: 425104:SSED_RS14055
uniprot id: A8FWR5
names: Subcellular Location Annotation
messages: Cell inner membrane

425104:SSED RS08230
gene id: 425104:SSED_RS08230
uniprot id: A8FTM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

425104:SSED RS02220
gene id: 425104:SSED_RS02220
uniprot id: A8FQA9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

425104:SSED RS17540
gene id: 425104:SSED_RS17540
uniprot id: A8FYN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

425104:SSED RS16640
gene id: 425104:SSED_RS16640
uniprot id: A8FY59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

425104:SSED RS03915
gene id: 425104:SSED_RS03915
uniprot id: A8FR99
names: Similarity
messages: Belongs to the peptidase S46 family.

425104:SSED RS15930
gene id: 425104:SSED_RS15930
uniprot id: A8FXS0
names: Similarity
messages: Belongs to the type III secretion exporter family.

425104:SSED RS02050
gene id: 425104:SSED_RS02050
uniprot id: A8FQ89
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

425104:SSED RS13020
gene id: 425104:SSED_RS13020
uniprot id: A8FW63
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS21270
gene id: 425104:SSED_RS21270
uniprot id: A8G0R3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS19235
gene id: 425104:SSED_RS19235
uniprot id: A8FZL0
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

425104:SSED RS03670
gene id: 425104:SSED_RS03670
uniprot id: A8FR53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

425104:SSED RS16585
gene id: 425104:SSED_RS16585
uniprot id: A8FY48
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS18775
gene id: 425104:SSED_RS18775
uniprot id: A8FZB8
names: Similarity
messages: Belongs to the BMP lipoprotein family.

425104:SSED RS09560
gene id: 425104:SSED_RS09560
uniprot id: A8FUD4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

425104:SSED RS10795
gene id: 425104:SSED_RS10795
uniprot id: A8FV07
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

425104:SSED RS11260
gene id: 425104:SSED_RS11260
uniprot id: A8FV90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

425104:SSED RS08115
gene id: 425104:SSED_RS08115
uniprot id: A8FTK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

425104:SSED RS23210
gene id: 425104:SSED_RS23210
uniprot id: A8G1S5
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

425104:SSED RS22155
gene id: 425104:SSED_RS22155
uniprot id: A8G181
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

425104:SSED RS03870
gene id: 425104:SSED_RS03870
uniprot id: A8FR91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

425104:SSED RS07200
gene id: 425104:SSED_RS07200
uniprot id: A8FT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

425104:SSED RS20050
gene id: 425104:SSED_RS20050
uniprot id: A8G019
names: Similarity
messages: Belongs to the PspA/IM30 family.

425104:SSED RS00105
gene id: 425104:SSED_RS00105
uniprot id: A8FP61
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

425104:SSED RS13830
gene id: 425104:SSED_RS13830
uniprot id: A8FWM0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

425104:SSED RS23635
gene id: 425104:SSED_RS23635
uniprot id: A8FV24
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

425104:SSED RS23515
gene id: 425104:SSED_RS23515
uniprot id: A8G1X8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

425104:SSED RS11645
gene id: 425104:SSED_RS11645
uniprot id: A8FVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

425104:SSED RS04490
gene id: 425104:SSED_RS04490
uniprot id: A8FRK9
names: Similarity
messages: Belongs to the TPP enzyme family.

425104:SSED RS12515
gene id: 425104:SSED_RS12515
uniprot id: A8FVX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

425104:SSED RS18615
gene id: 425104:SSED_RS18615
uniprot id: A8FZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

425104:SSED RS08780
gene id: 425104:SSED_RS08780
uniprot id: A8FTY6
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS09770
gene id: 425104:SSED_RS09770
uniprot id: A8FUG5
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

425104:SSED RS21570
gene id: 425104:SSED_RS21570
uniprot id: A8G0X1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00945
gene id: 425104:SSED_RS00945
uniprot id: A8FPM3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

425104:SSED RS17085
gene id: 425104:SSED_RS17085
uniprot id: A8FYE6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

425104:SSED RS11245
gene id: 425104:SSED_RS11245
uniprot id: A8FV87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

425104:SSED RS08535
gene id: 425104:SSED_RS08535
uniprot id: A8FTT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS17925
gene id: 425104:SSED_RS17925
uniprot id: A8FYW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

425104:SSED RS00280
gene id: 425104:SSED_RS00280
uniprot id: A8FP92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

425104:SSED RS15900
gene id: 425104:SSED_RS15900
uniprot id: A8FXR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

425104:SSED RS08150
gene id: 425104:SSED_RS08150
uniprot id: A8FTL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

425104:SSED RS22485
gene id: 425104:SSED_RS22485
uniprot id: A8G1E4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

425104:SSED RS04790
gene id: 425104:SSED_RS04790
uniprot id: A8FRR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 5 heme c groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
messages: Periplasm

425104:SSED RS18760
gene id: 425104:SSED_RS18760
uniprot id: A8FZB5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS20445
gene id: 425104:SSED_RS20445
uniprot id: A8G097
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

425104:SSED RS03045
gene id: 425104:SSED_RS03045
uniprot id: A8FQS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS10145
gene id: 425104:SSED_RS10145
uniprot id: A8FUN9
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS03210
gene id: 425104:SSED_RS03210
uniprot id: A8FQV8
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

425104:SSED RS04520
gene id: 425104:SSED_RS04520
uniprot id: A8FRL5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

425104:SSED RS23425
gene id: 425104:SSED_RS23425
uniprot id: A8G1W0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS14080
gene id: 425104:SSED_RS14080
uniprot id: A8FWS0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS22900
gene id: 425104:SSED_RS22900
uniprot id: A8G1L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

425104:SSED RS20105
gene id: 425104:SSED_RS20105
uniprot id: A8G030
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS21705
gene id: 425104:SSED_RS21705
uniprot id: A8G0Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

425104:SSED RS17385
gene id: 425104:SSED_RS17385
uniprot id: A8FYK6
names: Similarity
messages: Belongs to the MotB family.

425104:SSED RS18015
gene id: 425104:SSED_RS18015
uniprot id: A8FYY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

425104:SSED RS04220
gene id: 425104:SSED_RS04220
uniprot id: A8FRF5
names: Similarity
messages: Belongs to the aspartokinase family.

425104:SSED RS20380
gene id: 425104:SSED_RS20380
uniprot id: A8G084
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

425104:SSED RS03230
gene id: 425104:SSED_RS03230
uniprot id: A8FQW2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

425104:SSED RS11105
gene id: 425104:SSED_RS11105
uniprot id: A8FV61
names: Similarity
messages: Belongs to the AlaDH/PNT family.

425104:SSED RS10810
gene id: 425104:SSED_RS10810
uniprot id: A8FV10
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

425104:SSED RS15800
gene id: 425104:SSED_RS15800
uniprot id: A8FXP4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

425104:SSED RS23215
gene id: 425104:SSED_RS23215
uniprot id: A8G1S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

425104:SSED RS15095
gene id: 425104:SSED_RS15095
uniprot id: A8FXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

425104:SSED RS22705
gene id: 425104:SSED_RS22705
uniprot id: A8G1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

425104:SSED RS14715
gene id: 425104:SSED_RS14715
uniprot id: A8FX49
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

425104:SSED RS08085
gene id: 425104:SSED_RS08085
uniprot id: A8FTJ7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

425104:SSED RS17770
gene id: 425104:SSED_RS17770
uniprot id: A8FYT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

425104:SSED RS09855
gene id: 425104:SSED_RS09855
uniprot id: A8FUI2
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS05860
gene id: 425104:SSED_RS05860
uniprot id: A8FSD0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

425104:SSED RS22295
gene id: 425104:SSED_RS22295
uniprot id: A8G1A9
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

425104:SSED RS02815
gene id: 425104:SSED_RS02815
uniprot id: A8FQM7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

425104:SSED RS12695
gene id: 425104:SSED_RS12695
uniprot id: A8FW10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
messages: Belongs to the KdsB family.
messages: Cytoplasm

425104:SSED RS18055
gene id: 425104:SSED_RS18055
uniprot id: A8FYY9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

425104:SSED RS01500
gene id: 425104:SSED_RS01500
uniprot id: A8FPX9
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22730
gene id: 425104:SSED_RS22730
uniprot id: A8G1I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS01245
gene id: 425104:SSED_RS01245
uniprot id: A8FPT4
names: Subcellular Location Annotation
messages: Periplasm

425104:SSED RS02945
gene id: 425104:SSED_RS02945
uniprot id: A8FQQ3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

425104:SSED RS22360
gene id: 425104:SSED_RS22360
uniprot id: A8G1B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

425104:SSED RS13585
gene id: 425104:SSED_RS13585
uniprot id: A8FWH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS22075
gene id: 425104:SSED_RS22075
uniprot id: A8G167
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS02000
gene id: 425104:SSED_RS02000
uniprot id: A8FQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

425104:SSED RS07290
gene id: 425104:SSED_RS07290
uniprot id: A8FT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

425104:SSED RS06035
gene id: 425104:SSED_RS06035
uniprot id: A8FSG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

425104:SSED RS08540
gene id: 425104:SSED_RS08540
uniprot id: A8FTT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS12210
gene id: 425104:SSED_RS12210
uniprot id: A8FVR5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

425104:SSED RS14880
gene id: 425104:SSED_RS14880
uniprot id: A8FX81
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

425104:SSED RS01870
gene id: 425104:SSED_RS01870
uniprot id: A8FQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

425104:SSED RS04745
gene id: 425104:SSED_RS04745
uniprot id: A8FRR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane

425104:SSED RS06040
gene id: 425104:SSED_RS06040
uniprot id: A8FSG5
names: Similarity
messages: Belongs to the threonine synthase family.

425104:SSED RS16170
gene id: 425104:SSED_RS16170
uniprot id: A8FXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

425104:SSED RS05055
gene id: 425104:SSED_RS05055
uniprot id: A8FRX2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

425104:SSED RS11985
gene id: 425104:SSED_RS11985
uniprot id: A8FVM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS18915
gene id: 425104:SSED_RS18915
uniprot id: A8FZE6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS16100
gene id: 425104:SSED_RS16100
uniprot id: A8FXV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

425104:SSED RS19185
gene id: 425104:SSED_RS19185
uniprot id: A8FZK0
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS09250
gene id: 425104:SSED_RS09250
uniprot id: A8FU74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

425104:SSED RS20130
gene id: 425104:SSED_RS20130
uniprot id: A8G035
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS16855
gene id: 425104:SSED_RS16855
uniprot id: A8FYA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

425104:SSED RS22440
gene id: 425104:SSED_RS22440
uniprot id: A8G1D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

425104:SSED RS02010
gene id: 425104:SSED_RS02010
uniprot id: A8FQ81
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

425104:SSED RS21080
gene id: 425104:SSED_RS21080
uniprot id: A8G0M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

425104:SSED RS18230
gene id: 425104:SSED_RS18230
uniprot id: A8FZ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

425104:SSED RS15620
gene id: 425104:SSED_RS15620
uniprot id: A8FXK9
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS20755
gene id: 425104:SSED_RS20755
uniprot id: A8G0F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

425104:SSED RS13900
gene id: 425104:SSED_RS13900
uniprot id: A8FWN4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

425104:SSED RS00365
gene id: 425104:SSED_RS00365
uniprot id: A8FPA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

425104:SSED RS09550
gene id: 425104:SSED_RS09550
uniprot id: A8FUD2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

425104:SSED RS01945
gene id: 425104:SSED_RS01945
uniprot id: A8FQ68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

425104:SSED RS20385
gene id: 425104:SSED_RS20385
uniprot id: A8G085
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

425104:SSED RS00295
gene id: 425104:SSED_RS00295
uniprot id: A8FP95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

425104:SSED RS12630
gene id: 425104:SSED_RS12630
uniprot id: A8FVZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

425104:SSED RS16555
gene id: 425104:SSED_RS16555
uniprot id: A8FY42
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

425104:SSED RS04850
gene id: 425104:SSED_RS04850
uniprot id: A8FRT1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

425104:SSED RS07785
gene id: 425104:SSED_RS07785
uniprot id: A8FTE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

425104:SSED RS16020
gene id: 425104:SSED_RS16020
uniprot id: A8FXT8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

425104:SSED RS15700
gene id: 425104:SSED_RS15700
uniprot id: A8FXM4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

425104:SSED RS10265
gene id: 425104:SSED_RS10265
uniprot id: A8FUR3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

425104:SSED RS10790
gene id: 425104:SSED_RS10790
uniprot id: A8FV06
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS07990
gene id: 425104:SSED_RS07990
uniprot id: A8FTH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

425104:SSED RS01400
gene id: 425104:SSED_RS01400
uniprot id: A8FPW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS05965
gene id: 425104:SSED_RS05965
uniprot id: A8FSF0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

425104:SSED RS03025
gene id: 425104:SSED_RS03025
uniprot id: A8FQR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

425104:SSED RS13790
gene id: 425104:SSED_RS13790
uniprot id: A8FWL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

425104:SSED RS07490
gene id: 425104:SSED_RS07490
uniprot id: A8FT84
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

425104:SSED RS16025
gene id: 425104:SSED_RS16025
uniprot id: A8FXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

425104:SSED RS21645
gene id: 425104:SSED_RS21645
uniprot id: A8G0Y0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS22365
gene id: 425104:SSED_RS22365
uniprot id: A8G1C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

425104:SSED RS01290
gene id: 425104:SSED_RS01290
uniprot id: A8FPU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS19400
gene id: 425104:SSED_RS19400
uniprot id: A8FZP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS16560
gene id: 425104:SSED_RS16560
uniprot id: A8FY43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

425104:SSED RS02145
gene id: 425104:SSED_RS02145
uniprot id: A8FQA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

425104:SSED RS04115
gene id: 425104:SSED_RS04115
uniprot id: A8FRD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

425104:SSED RS09620
gene id: 425104:SSED_RS09620
uniprot id: A8FUE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

425104:SSED RS08555
gene id: 425104:SSED_RS08555
uniprot id: A8FTU1
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

425104:SSED RS13370
gene id: 425104:SSED_RS13370
uniprot id: A8FWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

425104:SSED RS11605
gene id: 425104:SSED_RS11605
uniprot id: A8FVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

425104:SSED RS13700
gene id: 425104:SSED_RS13700
uniprot id: A8FWJ4
names: Similarity
messages: Belongs to the CvfB family.

425104:SSED RS17425
gene id: 425104:SSED_RS17425
uniprot id: A8FYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

425104:SSED RS06330
gene id: 425104:SSED_RS06330
uniprot id: A8FSL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

425104:SSED RS13120
gene id: 425104:SSED_RS13120
uniprot id: A8FW83
names: Similarity
messages: Belongs to the peptidase S51 family.

425104:SSED RS21415
gene id: 425104:SSED_RS21415
uniprot id: A8G0U1
names: Similarity
messages: Belongs to the thioredoxin family.

425104:SSED RS01095
gene id: 425104:SSED_RS01095
uniprot id: A8FPQ4
names: Similarity
messages: Belongs to the UPF0319 family.

425104:SSED RS12675
gene id: 425104:SSED_RS12675
uniprot id: A8FW07
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

425104:SSED RS22375
gene id: 425104:SSED_RS22375
uniprot id: A8G1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

425104:SSED RS01955
gene id: 425104:SSED_RS01955
uniprot id: A8FQ70
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

425104:SSED RS00735
gene id: 425104:SSED_RS00735
uniprot id: A8FPI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

425104:SSED RS09955
gene id: 425104:SSED_RS09955
uniprot id: A8FUK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS16925
gene id: 425104:SSED_RS16925
uniprot id: A8FYB5
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS12000
gene id: 425104:SSED_RS12000
uniprot id: A8FVM3
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS17175
gene id: 425104:SSED_RS17175
uniprot id: A8FYG4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

425104:SSED RS07245
gene id: 425104:SSED_RS07245
uniprot id: A8FT37
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00300
gene id: 425104:SSED_RS00300
uniprot id: A8FP96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

425104:SSED RS16895
gene id: 425104:SSED_RS16895
uniprot id: A8FYA9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

425104:SSED RS09395
gene id: 425104:SSED_RS09395
uniprot id: A8FUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS08395
gene id: 425104:SSED_RS08395
uniprot id: A8FTQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS06535
gene id: 425104:SSED_RS06535
uniprot id: A8FSR0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

425104:SSED RS03050
gene id: 425104:SSED_RS03050
uniprot id: A8FQS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS16935
gene id: 425104:SSED_RS16935
uniprot id: A8FYB7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS04725
gene id: 425104:SSED_RS04725
uniprot id: A8FRQ6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS17265
gene id: 425104:SSED_RS17265
uniprot id: A8FYI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

425104:SSED RS22405
gene id: 425104:SSED_RS22405
uniprot id: A8G1C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

425104:SSED RS18715
gene id: 425104:SSED_RS18715
uniprot id: A8FZA6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS07955
gene id: 425104:SSED_RS07955
uniprot id: A8FTH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

425104:SSED RS05985
gene id: 425104:SSED_RS05985
uniprot id: A8FSF4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS13345
gene id: 425104:SSED_RS13345
uniprot id: A8FWC5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

425104:SSED RS14830
gene id: 425104:SSED_RS14830
uniprot id: A8FX72
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

425104:SSED RS08910
gene id: 425104:SSED_RS08910
uniprot id: A8FU12
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS10035
gene id: 425104:SSED_RS10035
uniprot id: A8FUM1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

425104:SSED RS03755
gene id: 425104:SSED_RS03755
uniprot id: A8FR68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

425104:SSED RS22470
gene id: 425104:SSED_RS22470
uniprot id: A8G1E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

425104:SSED RS07505
gene id: 425104:SSED_RS07505
uniprot id: A8FT87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

425104:SSED RS16145
gene id: 425104:SSED_RS16145
uniprot id: A8FXW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

425104:SSED RS06560
gene id: 425104:SSED_RS06560
uniprot id: A8FSR5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

425104:SSED RS02245
gene id: 425104:SSED_RS02245
uniprot id: A8FQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS17255
gene id: 425104:SSED_RS17255
uniprot id: A8FYI0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

425104:SSED RS08815
gene id: 425104:SSED_RS08815
uniprot id: A8FTZ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

425104:SSED RS06620
gene id: 425104:SSED_RS06620
uniprot id: A8FSS7
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

425104:SSED RS21520
gene id: 425104:SSED_RS21520
uniprot id: A8G0W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

425104:SSED RS09520
gene id: 425104:SSED_RS09520
uniprot id: A8FUC6
names: Similarity
messages: Belongs to the asparagine synthetase family.

425104:SSED RS13910
gene id: 425104:SSED_RS13910
uniprot id: A8FWN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

425104:SSED RS09490
gene id: 425104:SSED_RS09490
uniprot id: A8FUC0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS01930
gene id: 425104:SSED_RS01930
uniprot id: A8FQ65
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

425104:SSED RS16500
gene id: 425104:SSED_RS16500
uniprot id: A8FY31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

425104:SSED RS02730
gene id: 425104:SSED_RS02730
uniprot id: A8FQL0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS02030
gene id: 425104:SSED_RS02030
uniprot id: A8FQ85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

425104:SSED RS17805
gene id: 425104:SSED_RS17805
uniprot id: A8FYT7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS07930
gene id: 425104:SSED_RS07930
uniprot id: A8FTG9
names: Similarity
messages: Belongs to the FeoA family.

425104:SSED RS07425
gene id: 425104:SSED_RS07425
uniprot id: A8FT72
names: Similarity
messages: Belongs to the YfgM family.

425104:SSED RS10320
gene id: 425104:SSED_RS10320
uniprot id: A8FUS4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

425104:SSED RS09690
gene id: 425104:SSED_RS09690
uniprot id: A8FUE9
names: Subunit
messages: Monomer.

425104:SSED RS02430
gene id: 425104:SSED_RS02430
uniprot id: A8FQF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

425104:SSED RS08390
gene id: 425104:SSED_RS08390
uniprot id: A8FTQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

425104:SSED RS04985
gene id: 425104:SSED_RS04985
uniprot id: A8FRV8
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

425104:SSED RS13190
gene id: 425104:SSED_RS13190
uniprot id: A8FW95
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00320
gene id: 425104:SSED_RS00320
uniprot id: A8FPA0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

425104:SSED RS07590
gene id: 425104:SSED_RS07590
uniprot id: A8FTA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

425104:SSED RS00645
gene id: 425104:SSED_RS00645
uniprot id: A8FPG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS12800
gene id: 425104:SSED_RS12800
uniprot id: A8FW31
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

425104:SSED RS04585
gene id: 425104:SSED_RS04585
uniprot id: A8FRM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

425104:SSED RS13045
gene id: 425104:SSED_RS13045
uniprot id: A8FW68
names: Similarity
messages: Belongs to the peptidase M1 family.

425104:SSED RS01950
gene id: 425104:SSED_RS01950
uniprot id: A8FQ69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

425104:SSED RS13800
gene id: 425104:SSED_RS13800
uniprot id: A8FWL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

425104:SSED RS21385
gene id: 425104:SSED_RS21385
uniprot id: A8G0T6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

425104:SSED RS07705
gene id: 425104:SSED_RS07705
uniprot id: A8FTC6
names: Similarity
messages: Belongs to the peptidase M17 family.

425104:SSED RS11790
gene id: 425104:SSED_RS11790
uniprot id: A8FVI3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

425104:SSED RS22410
gene id: 425104:SSED_RS22410
uniprot id: A8G1C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

425104:SSED RS02230
gene id: 425104:SSED_RS02230
uniprot id: A8FQB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

425104:SSED RS22685
gene id: 425104:SSED_RS22685
uniprot id: A8G1H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

425104:SSED RS02505
gene id: 425104:SSED_RS02505
uniprot id: A8FQG5
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS14865
gene id: 425104:SSED_RS14865
uniprot id: A8FX78
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS08580
gene id: 425104:SSED_RS08580
uniprot id: A8FTU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

425104:SSED RS11925
gene id: 425104:SSED_RS11925
uniprot id: A8FVK9
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

425104:SSED RS13780
gene id: 425104:SSED_RS13780
uniprot id: A8FWL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

425104:SSED RS20355
gene id: 425104:SSED_RS20355
uniprot id: A8G079
names: Similarity
messages: Belongs to the SfsA family.

425104:SSED RS02780
gene id: 425104:SSED_RS02780
uniprot id: A8FQM0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

425104:SSED RS14070
gene id: 425104:SSED_RS14070
uniprot id: A8FWR8
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

425104:SSED RS15540
gene id: 425104:SSED_RS15540
uniprot id: A8FXJ3
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS20955
gene id: 425104:SSED_RS20955
uniprot id: A8G0J9
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

425104:SSED RS14220
gene id: 425104:SSED_RS14220
uniprot id: A8FWU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

425104:SSED RS19965
gene id: 425104:SSED_RS19965
uniprot id: A8G002
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell inner membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

425104:SSED RS21090
gene id: 425104:SSED_RS21090
uniprot id: A8G0M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

425104:SSED RS00880
gene id: 425104:SSED_RS00880
uniprot id: A8FPL0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

425104:SSED RS09450
gene id: 425104:SSED_RS09450
uniprot id: A8FUB2
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

425104:SSED RS00545
gene id: 425104:SSED_RS00545
uniprot id: A8FPE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

425104:SSED RS12955
gene id: 425104:SSED_RS12955
uniprot id: A8FW54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

425104:SSED RS04825
gene id: 425104:SSED_RS04825
uniprot id: A8FRS7
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS01720
gene id: 425104:SSED_RS01720
uniprot id: A8FQ23
names: Similarity
messages: Belongs to the RutC family.

425104:SSED RS18205
gene id: 425104:SSED_RS18205
uniprot id: A8FZ11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

425104:SSED RS06540
gene id: 425104:SSED_RS06540
uniprot id: A8FSR1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

425104:SSED RS06975
gene id: 425104:SSED_RS06975
uniprot id: A8FSY5
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

425104:SSED RS14760
gene id: 425104:SSED_RS14760
uniprot id: A8FX58
names: Similarity
messages: Belongs to the UPF0434 family.

425104:SSED RS09905
gene id: 425104:SSED_RS09905
uniprot id: A8FUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

425104:SSED RS02100
gene id: 425104:SSED_RS02100
uniprot id: A8FQ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that is essential for cell division.

425104:SSED RS01605
gene id: 425104:SSED_RS01605
uniprot id: A8FQ00
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

425104:SSED RS05220
gene id: 425104:SSED_RS05220
uniprot id: A8FS03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

425104:SSED RS17665
gene id: 425104:SSED_RS17665
uniprot id: A8FYR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS07970
gene id: 425104:SSED_RS07970
uniprot id: A8FTH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

425104:SSED RS10855
gene id: 425104:SSED_RS10855
uniprot id: A8FV19
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

425104:SSED RS21855
gene id: 425104:SSED_RS21855
uniprot id: A8G122
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

425104:SSED RS09950
gene id: 425104:SSED_RS09950
uniprot id: A8FUK3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

425104:SSED RS06600
gene id: 425104:SSED_RS06600
uniprot id: A8FSS3
names: Subcellular Location Annotation
messages: Cell inner membrane

425104:SSED RS16155
gene id: 425104:SSED_RS16155
uniprot id: A8FXW5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

425104:SSED RS01200
gene id: 425104:SSED_RS01200
uniprot id: A8FPS5
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS12505
gene id: 425104:SSED_RS12505
uniprot id: A8FVX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

425104:SSED RS11650
gene id: 425104:SSED_RS11650
uniprot id: A8FVG1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

425104:SSED RS16135
gene id: 425104:SSED_RS16135
uniprot id: A8FXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

425104:SSED RS17505
gene id: 425104:SSED_RS17505
uniprot id: A8FYN0
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

425104:SSED RS10525
gene id: 425104:SSED_RS10525
uniprot id: A8FUW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

425104:SSED RS22560
gene id: 425104:SSED_RS22560
uniprot id: A8G1F9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

425104:SSED RS18920
gene id: 425104:SSED_RS18920
uniprot id: A8FZE7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

425104:SSED RS02585
gene id: 425104:SSED_RS02585
uniprot id: A8FQI1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS03020
gene id: 425104:SSED_RS03020
uniprot id: A8FQR8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS17390
gene id: 425104:SSED_RS17390
uniprot id: A8FYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

425104:SSED RS16880
gene id: 425104:SSED_RS16880
uniprot id: A8FYA6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

425104:SSED RS18820
gene id: 425104:SSED_RS18820
uniprot id: A8FZC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

425104:SSED RS03500
gene id: 425104:SSED_RS03500
uniprot id: A8FR19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

425104:SSED RS04125
gene id: 425104:SSED_RS04125
uniprot id: A8FRD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

425104:SSED RS01025
gene id: 425104:SSED_RS01025
uniprot id: A8FPP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

425104:SSED RS01125
gene id: 425104:SSED_RS01125
uniprot id: A8FPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

425104:SSED RS06455
gene id: 425104:SSED_RS06455
uniprot id: A8FSP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS09890
gene id: 425104:SSED_RS09890
uniprot id: A8FUJ1
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

425104:SSED RS14095
gene id: 425104:SSED_RS14095
uniprot id: A8FWS3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

425104:SSED RS17640
gene id: 425104:SSED_RS17640
uniprot id: A8FYQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

425104:SSED RS20005
gene id: 425104:SSED_RS20005
uniprot id: A8G010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

425104:SSED RS07995
gene id: 425104:SSED_RS07995
uniprot id: A8FTH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

425104:SSED RS17355
gene id: 425104:SSED_RS17355
uniprot id: A8FYK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS05050
gene id: 425104:SSED_RS05050
uniprot id: A8FRX1
names: Similarity
messages: Belongs to the MipA/OmpV family.

425104:SSED RS22960
gene id: 425104:SSED_RS22960
uniprot id: A8G1M8
names: Similarity
messages: Belongs to the MoaD family.

425104:SSED RS21265
gene id: 425104:SSED_RS21265
uniprot id: A8G0R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

425104:SSED RS12655
gene id: 425104:SSED_RS12655
uniprot id: A8FW03
names: Similarity
messages: Belongs to the ArsC family.

425104:SSED RS14870
gene id: 425104:SSED_RS14870
uniprot id: A8FX79
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

425104:SSED RS05265
gene id: 425104:SSED_RS05265
uniprot id: A8FS12
names: Similarity
messages: Belongs to the peptidase M24B family.

425104:SSED RS22495
gene id: 425104:SSED_RS22495
uniprot id: A8G1E6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

425104:SSED RS01515
gene id: 425104:SSED_RS01515
uniprot id: A8FPY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

425104:SSED RS14690
gene id: 425104:SSED_RS14690
uniprot id: A8FX44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS09600
gene id: 425104:SSED_RS09600
uniprot id: A8FUE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

425104:SSED RS15005
gene id: 425104:SSED_RS15005
uniprot id: A8FXA7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

425104:SSED RS04800
gene id: 425104:SSED_RS04800
uniprot id: A8FRS1
names: Similarity
messages: Belongs to the P(II) protein family.

425104:SSED RS17395
gene id: 425104:SSED_RS17395
uniprot id: A8FYK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

425104:SSED RS19995
gene id: 425104:SSED_RS19995
uniprot id: A8G008
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS10775
gene id: 425104:SSED_RS10775
uniprot id: A8FV03
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

425104:SSED RS21680
gene id: 425104:SSED_RS21680
uniprot id: A8G0Y7
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS06190
gene id: 425104:SSED_RS06190
uniprot id: A8FSJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS00455
gene id: 425104:SSED_RS00455
uniprot id: A8FPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

425104:SSED RS13275
gene id: 425104:SSED_RS13275
uniprot id: A8FWB2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

425104:SSED RS12015
gene id: 425104:SSED_RS12015
uniprot id: A8FVM7
names: Similarity
messages: Belongs to the peptidase S13 family.

425104:SSED RS05680
gene id: 425104:SSED_RS05680
uniprot id: A8FS93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

425104:SSED RS20960
gene id: 425104:SSED_RS20960
uniprot id: A8G0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

425104:SSED RS20080
gene id: 425104:SSED_RS20080
uniprot id: A8G025
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

425104:SSED RS04965
gene id: 425104:SSED_RS04965
uniprot id: A8FRV4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

425104:SSED RS10595
gene id: 425104:SSED_RS10595
uniprot id: A8FUX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

425104:SSED RS13645
gene id: 425104:SSED_RS13645
uniprot id: A8FWI2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

425104:SSED RS20645
gene id: 425104:SSED_RS20645
uniprot id: A8G0D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

425104:SSED RS16330
gene id: 425104:SSED_RS16330
uniprot id: A8FXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS12750
gene id: 425104:SSED_RS12750
uniprot id: A8FW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

425104:SSED RS12305
gene id: 425104:SSED_RS12305
uniprot id: A8FVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS20375
gene id: 425104:SSED_RS20375
uniprot id: A8G083
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

425104:SSED RS04590
gene id: 425104:SSED_RS04590
uniprot id: A8FRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

425104:SSED RS13480
gene id: 425104:SSED_RS13480
uniprot id: A8FWF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS13400
gene id: 425104:SSED_RS13400
uniprot id: A8FWD6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

425104:SSED RS07495
gene id: 425104:SSED_RS07495
uniprot id: A8FT85
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00755
gene id: 425104:SSED_RS00755
uniprot id: A8FPI5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

425104:SSED RS15550
gene id: 425104:SSED_RS15550
uniprot id: A8FXJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

425104:SSED RS22000
gene id: 425104:SSED_RS22000
uniprot id: A8G151
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

425104:SSED RS15435
gene id: 425104:SSED_RS15435
uniprot id: A8FXH3
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

425104:SSED RS21850
gene id: 425104:SSED_RS21850
uniprot id: A8G121
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS03395
gene id: 425104:SSED_RS03395
uniprot id: A8FQZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS23460
gene id: 425104:SSED_RS23460
uniprot id: A8G1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

425104:SSED RS10915
gene id: 425104:SSED_RS10915
uniprot id: A8FV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

425104:SSED RS14530
gene id: 425104:SSED_RS14530
uniprot id: A8FX11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS10840
gene id: 425104:SSED_RS10840
uniprot id: A8FV16
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

425104:SSED RS15400
gene id: 425104:SSED_RS15400
uniprot id: A8FXG6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

425104:SSED RS24420
gene id: 425104:SSED_RS24420
uniprot id: A8FR69
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

425104:SSED RS09935
gene id: 425104:SSED_RS09935
uniprot id: A8FUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

425104:SSED RS14540
gene id: 425104:SSED_RS14540
uniprot id: A8FX13
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

425104:SSED RS04055
gene id: 425104:SSED_RS04055
uniprot id: A8FRC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

425104:SSED RS04130
gene id: 425104:SSED_RS04130
uniprot id: A8FRD8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

425104:SSED RS12030
gene id: 425104:SSED_RS12030
uniprot id: A8FVN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

425104:SSED RS13945
gene id: 425104:SSED_RS13945
uniprot id: A8FWP3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

425104:SSED RS12760
gene id: 425104:SSED_RS12760
uniprot id: A8FW23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

425104:SSED RS10550
gene id: 425104:SSED_RS10550
uniprot id: A8FUW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

425104:SSED RS08510
gene id: 425104:SSED_RS08510
uniprot id: A8FTT2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

425104:SSED RS16735
gene id: 425104:SSED_RS16735
uniprot id: A8FY78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

425104:SSED RS23675
gene id: 425104:SSED_RS23675
uniprot id: A8FWT8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

425104:SSED RS09870
gene id: 425104:SSED_RS09870
uniprot id: A8FUI7
names: Similarity
messages: Belongs to the HypE family.

425104:SSED RS01985
gene id: 425104:SSED_RS01985
uniprot id: A8FQ76
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

425104:SSED RS20190
gene id: 425104:SSED_RS20190
uniprot id: A8G047
names: Similarity
messages: Belongs to the UPF0270 family.

425104:SSED RS03480
gene id: 425104:SSED_RS03480
uniprot id: A8FR15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS08920
gene id: 425104:SSED_RS08920
uniprot id: A8FU14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

425104:SSED RS06030
gene id: 425104:SSED_RS06030
uniprot id: A8FSG3
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

425104:SSED RS01105
gene id: 425104:SSED_RS01105
uniprot id: A8FPQ6
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

425104:SSED RS17835
gene id: 425104:SSED_RS17835
uniprot id: A8FYU3
names: Function
names: Similarity
messages: Belongs to the peptidase S9C family.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

425104:SSED RS06505
gene id: 425104:SSED_RS06505
uniprot id: A8FSQ4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS20730
gene id: 425104:SSED_RS20730
uniprot id: A8G0F4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

425104:SSED RS11705
gene id: 425104:SSED_RS11705
uniprot id: A8FVG6
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

425104:SSED RS23155
gene id: 425104:SSED_RS23155
uniprot id: A8G1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS20420
gene id: 425104:SSED_RS20420
uniprot id: A8G092
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS05535
gene id: 425104:SSED_RS05535
uniprot id: A8FS64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

425104:SSED RS10660
gene id: 425104:SSED_RS10660
uniprot id: A8FUY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

425104:SSED RS02985
gene id: 425104:SSED_RS02985
uniprot id: A8FQR1
names: Similarity
messages: Belongs to the peptidase U62 family.

425104:SSED RS03665
gene id: 425104:SSED_RS03665
uniprot id: A8FR52
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS09940
gene id: 425104:SSED_RS09940
uniprot id: A8FUK1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

425104:SSED RS10340
gene id: 425104:SSED_RS10340
uniprot id: A8FUS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

425104:SSED RS21450
gene id: 425104:SSED_RS21450
uniprot id: A8G0U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

425104:SSED RS02225
gene id: 425104:SSED_RS02225
uniprot id: A8FQB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

425104:SSED RS19075
gene id: 425104:SSED_RS19075
uniprot id: A8FZH8
names: Similarity
messages: Belongs to the peptidase S33 family.

425104:SSED RS15995
gene id: 425104:SSED_RS15995
uniprot id: A8FXT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

425104:SSED RS05975
gene id: 425104:SSED_RS05975
uniprot id: A8FSF2
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS10025
gene id: 425104:SSED_RS10025
uniprot id: A8FUL9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

425104:SSED RS06140
gene id: 425104:SSED_RS06140
uniprot id: A8FSI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

425104:SSED RS22840
gene id: 425104:SSED_RS22840
uniprot id: A8G1K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

425104:SSED RS09350
gene id: 425104:SSED_RS09350
uniprot id: A8FU94
names: Similarity
messages: Belongs to the elongation factor P family.

425104:SSED RS10345
gene id: 425104:SSED_RS10345
uniprot id: A8FUS9
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

425104:SSED RS21355
gene id: 425104:SSED_RS21355
uniprot id: A8G0T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

425104:SSED RS01385
gene id: 425104:SSED_RS01385
uniprot id: A8FPW3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

425104:SSED RS03525
gene id: 425104:SSED_RS03525
uniprot id: A8FR24
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

425104:SSED RS21735
gene id: 425104:SSED_RS21735
uniprot id: A8G0Z8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS01730
gene id: 425104:SSED_RS01730
uniprot id: A8FQ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

425104:SSED RS21305
gene id: 425104:SSED_RS21305
uniprot id: A8G0S0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

425104:SSED RS01845
gene id: 425104:SSED_RS01845
uniprot id: A8FQ48
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

425104:SSED RS02540
gene id: 425104:SSED_RS02540
uniprot id: A8FQH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multiheme cytochrome c family.
messages: Binds 8 heme c groups covalently per monomer.
messages: Exposure to oxygen reduces copper binding and leads to the formation of a disulfide bond between the two Cys residues that bind the copper ion.
messages: Periplasm
messages: Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process.

425104:SSED RS21125
gene id: 425104:SSED_RS21125
uniprot id: A8G0N3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

425104:SSED RS02110
gene id: 425104:SSED_RS02110
uniprot id: A8FQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

425104:SSED RS14790
gene id: 425104:SSED_RS14790
uniprot id: A8FX64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

425104:SSED RS14805
gene id: 425104:SSED_RS14805
uniprot id: A8FX67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

425104:SSED RS22195
gene id: 425104:SSED_RS22195
uniprot id: A8G189
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

425104:SSED RS04420
gene id: 425104:SSED_RS04420
uniprot id: A8FRJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

425104:SSED RS12645
gene id: 425104:SSED_RS12645
uniprot id: A8FW01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

425104:SSED RS17420
gene id: 425104:SSED_RS17420
uniprot id: A8FYL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

425104:SSED RS05570
gene id: 425104:SSED_RS05570
uniprot id: A8FS71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

425104:SSED RS16730
gene id: 425104:SSED_RS16730
uniprot id: A8FY77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

425104:SSED RS17630
gene id: 425104:SSED_RS17630
uniprot id: A8FYQ4
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

425104:SSED RS19665
gene id: 425104:SSED_RS19665
uniprot id: A8FZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS01975
gene id: 425104:SSED_RS01975
uniprot id: A8FQ74
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

425104:SSED RS16665
gene id: 425104:SSED_RS16665
uniprot id: A8FY64
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS08670
gene id: 425104:SSED_RS08670
uniprot id: A8FTW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS19120
gene id: 425104:SSED_RS19120
uniprot id: A8FZI7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

425104:SSED RS20515
gene id: 425104:SSED_RS20515
uniprot id: A8G0B1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS16010
gene id: 425104:SSED_RS16010
uniprot id: A8FXT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

425104:SSED RS00360
gene id: 425104:SSED_RS00360
uniprot id: A8FPA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

425104:SSED RS02285
gene id: 425104:SSED_RS02285
uniprot id: A8FQC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

425104:SSED RS04430
gene id: 425104:SSED_RS04430
uniprot id: A8FRJ7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

425104:SSED RS03940
gene id: 425104:SSED_RS03940
uniprot id: A8FRA4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

425104:SSED RS10285
gene id: 425104:SSED_RS10285
uniprot id: A8FUR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

425104:SSED RS10805
gene id: 425104:SSED_RS10805
uniprot id: A8FV09
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

425104:SSED RS16335
gene id: 425104:SSED_RS16335
uniprot id: A8FY00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

425104:SSED RS22945
gene id: 425104:SSED_RS22945
uniprot id: A8G1M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

425104:SSED RS14725
gene id: 425104:SSED_RS14725
uniprot id: A8FX51
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

425104:SSED RS01905
gene id: 425104:SSED_RS01905
uniprot id: A8FQ60
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS07655
gene id: 425104:SSED_RS07655
uniprot id: A8FTB6
names: Similarity
messages: Belongs to the HIBADH-related family.

425104:SSED RS08210
gene id: 425104:SSED_RS08210
uniprot id: A8FTM2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS13870
gene id: 425104:SSED_RS13870
uniprot id: A8FWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

425104:SSED RS16815
gene id: 425104:SSED_RS16815
uniprot id: A8FY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

425104:SSED RS00390
gene id: 425104:SSED_RS00390
uniprot id: A8FPB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

425104:SSED RS13705
gene id: 425104:SSED_RS13705
uniprot id: A8FWJ5
names: Similarity
messages: Belongs to the UPF0502 family.

425104:SSED RS13360
gene id: 425104:SSED_RS13360
uniprot id: A8FWC8
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

425104:SSED RS22555
gene id: 425104:SSED_RS22555
uniprot id: A8G1F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

425104:SSED RS16505
gene id: 425104:SSED_RS16505
uniprot id: A8FY32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

425104:SSED RS05170
gene id: 425104:SSED_RS05170
uniprot id: A8FRZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

425104:SSED RS04955
gene id: 425104:SSED_RS04955
uniprot id: A8FRV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

425104:SSED RS02235
gene id: 425104:SSED_RS02235
uniprot id: A8FQB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

425104:SSED RS05255
gene id: 425104:SSED_RS05255
uniprot id: A8FS10
names: Similarity
messages: Belongs to the DEAD box helicase family.

425104:SSED RS04640
gene id: 425104:SSED_RS04640
uniprot id: A8FRN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS16545
gene id: 425104:SSED_RS16545
uniprot id: A8FY40
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS22715
gene id: 425104:SSED_RS22715
uniprot id: A8G1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS09435
gene id: 425104:SSED_RS09435
uniprot id: A8FUA9
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS07000
gene id: 425104:SSED_RS07000
uniprot id: A8FSZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

425104:SSED RS13785
gene id: 425104:SSED_RS13785
uniprot id: A8FWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

425104:SSED RS09175
gene id: 425104:SSED_RS09175
uniprot id: A8FU64
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS06050
gene id: 425104:SSED_RS06050
uniprot id: A8FSG7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

425104:SSED RS17045
gene id: 425104:SSED_RS17045
uniprot id: A8FYD8
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS03735
gene id: 425104:SSED_RS03735
uniprot id: A8FR64
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

425104:SSED RS13770
gene id: 425104:SSED_RS13770
uniprot id: A8FWK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

425104:SSED RS14255
gene id: 425104:SSED_RS14255
uniprot id: A8FWV7
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS08155
gene id: 425104:SSED_RS08155
uniprot id: A8FTL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

425104:SSED RS11100
gene id: 425104:SSED_RS11100
uniprot id: A8FV60
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

425104:SSED RS18725
gene id: 425104:SSED_RS18725
uniprot id: A8FZA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

425104:SSED RS05835
gene id: 425104:SSED_RS05835
uniprot id: A8FSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

425104:SSED RS18160
gene id: 425104:SSED_RS18160
uniprot id: A8FZ02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS09900
gene id: 425104:SSED_RS09900
uniprot id: A8FUJ3
names: Similarity
messages: Belongs to the peptidase A31 family.

425104:SSED RS12355
gene id: 425104:SSED_RS12355
uniprot id: A8FVU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

425104:SSED RS13635
gene id: 425104:SSED_RS13635
uniprot id: A8FWI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

425104:SSED RS03315
gene id: 425104:SSED_RS03315
uniprot id: A8FQY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

425104:SSED RS11270
gene id: 425104:SSED_RS11270
uniprot id: A8FV92
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

425104:SSED RS18455
gene id: 425104:SSED_RS18455
uniprot id: A8FZ55
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS02655
gene id: 425104:SSED_RS02655
uniprot id: A8FQJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

425104:SSED RS07965
gene id: 425104:SSED_RS07965
uniprot id: A8FTH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS21755
gene id: 425104:SSED_RS21755
uniprot id: A8G102
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

425104:SSED RS09020
gene id: 425104:SSED_RS09020
uniprot id: A8FU34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

425104:SSED RS07550
gene id: 425104:SSED_RS07550
uniprot id: A8FT96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

425104:SSED RS06565
gene id: 425104:SSED_RS06565
uniprot id: A8FSR6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

425104:SSED RS11005
gene id: 425104:SSED_RS11005
uniprot id: A8FV47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

425104:SSED RS09805
gene id: 425104:SSED_RS09805
uniprot id: A8FUH2
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS19650
gene id: 425104:SSED_RS19650
uniprot id: A8FZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

425104:SSED RS09580
gene id: 425104:SSED_RS09580
uniprot id: A8FUD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

425104:SSED RS18665
gene id: 425104:SSED_RS18665
uniprot id: A8FZ96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS04735
gene id: 425104:SSED_RS04735
uniprot id: A8FRQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

425104:SSED RS12745
gene id: 425104:SSED_RS12745
uniprot id: A8FW20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS02320
gene id: 425104:SSED_RS02320
uniprot id: A8FQC9
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

425104:SSED RS21515
gene id: 425104:SSED_RS21515
uniprot id: A8G0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS10470
gene id: 425104:SSED_RS10470
uniprot id: A8FUV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

425104:SSED RS00210
gene id: 425104:SSED_RS00210
uniprot id: A8FP82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

425104:SSED RS04095
gene id: 425104:SSED_RS04095
uniprot id: A8FRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

425104:SSED RS08135
gene id: 425104:SSED_RS08135
uniprot id: A8FTK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS15835
gene id: 425104:SSED_RS15835
uniprot id: A8FXQ1
names: Similarity
messages: Belongs to the bacterial secretin family.

425104:SSED RS19940
gene id: 425104:SSED_RS19940
uniprot id: A8FZZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

425104:SSED RS07860
gene id: 425104:SSED_RS07860
uniprot id: A8FTF5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

425104:SSED RS01285
gene id: 425104:SSED_RS01285
uniprot id: A8FPU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS18535
gene id: 425104:SSED_RS18535
uniprot id: A8FZ71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

425104:SSED RS11390
gene id: 425104:SSED_RS11390
uniprot id: A8FVB6
names: Similarity
messages: Belongs to the peptidase S16 family.

425104:SSED RS15520
gene id: 425104:SSED_RS15520
uniprot id: A8FXI9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

425104:SSED RS00520
gene id: 425104:SSED_RS00520
uniprot id: A8FPD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

425104:SSED RS17705
gene id: 425104:SSED_RS17705
uniprot id: A8FYR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

425104:SSED RS18510
gene id: 425104:SSED_RS18510
uniprot id: A8FZ66
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS09035
gene id: 425104:SSED_RS09035
uniprot id: A8FU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

425104:SSED RS17680
gene id: 425104:SSED_RS17680
uniprot id: A8FYR4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

425104:SSED RS07110
gene id: 425104:SSED_RS07110
uniprot id: A8FT11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS06085
gene id: 425104:SSED_RS06085
uniprot id: A8FSH4
names: Similarity
messages: Belongs to the XFP family.

425104:SSED RS04895
gene id: 425104:SSED_RS04895
uniprot id: A8FRU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

425104:SSED RS14925
gene id: 425104:SSED_RS14925
uniprot id: A8FX91
names: Similarity
messages: Belongs to the UPF0276 family.

425104:SSED RS19475
gene id: 425104:SSED_RS19475
uniprot id: A8FZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

425104:SSED RS16790
gene id: 425104:SSED_RS16790
uniprot id: A8FY88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

425104:SSED RS22595
gene id: 425104:SSED_RS22595
uniprot id: A8G1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

425104:SSED RS08040
gene id: 425104:SSED_RS08040
uniprot id: A8FTI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

425104:SSED RS06345
gene id: 425104:SSED_RS06345
uniprot id: A8FSM2
names: Similarity
messages: Belongs to the GSP E family.

425104:SSED RS12615
gene id: 425104:SSED_RS12615
uniprot id: A8FVZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

425104:SSED RS21130
gene id: 425104:SSED_RS21130
uniprot id: A8G0N4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

425104:SSED RS15350
gene id: 425104:SSED_RS15350
uniprot id: A8FXF6
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

425104:SSED RS14980
gene id: 425104:SSED_RS14980
uniprot id: A8FXA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

425104:SSED RS18425
gene id: 425104:SSED_RS18425
uniprot id: A8FZ49
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

425104:SSED RS08785
gene id: 425104:SSED_RS08785
uniprot id: A8FTY7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

425104:SSED RS24425
gene id: 425104:SSED_RS24425
uniprot id: A8FR70
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS12040
gene id: 425104:SSED_RS12040
uniprot id: A8FVN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS14785
gene id: 425104:SSED_RS14785
uniprot id: A8FX63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

425104:SSED RS10105
gene id: 425104:SSED_RS10105
uniprot id: A8FUN3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

425104:SSED RS17270
gene id: 425104:SSED_RS17270
uniprot id: A8FYI3
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

425104:SSED RS06355
gene id: 425104:SSED_RS06355
uniprot id: A8FSM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

425104:SSED RS16425
gene id: 425104:SSED_RS16425
uniprot id: A8FY16
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS07775
gene id: 425104:SSED_RS07775
uniprot id: A8FTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS09370
gene id: 425104:SSED_RS09370
uniprot id: A8FU97
names: Similarity
messages: Belongs to the UPF0352 family.

425104:SSED RS04340
gene id: 425104:SSED_RS04340
uniprot id: A8FRH9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS06985
gene id: 425104:SSED_RS06985
uniprot id: A8FSY7
names: Similarity
messages: Belongs to the YjdM family.

425104:SSED RS21975
gene id: 425104:SSED_RS21975
uniprot id: A8G146
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

425104:SSED RS03420
gene id: 425104:SSED_RS03420
uniprot id: A8FR02
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

425104:SSED RS00515
gene id: 425104:SSED_RS00515
uniprot id: A8FPD8
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22270
gene id: 425104:SSED_RS22270
uniprot id: A8G1A4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

425104:SSED RS10290
gene id: 425104:SSED_RS10290
uniprot id: A8FUR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

425104:SSED RS21825
gene id: 425104:SSED_RS21825
uniprot id: A8G116
names: Subcellular Location Annotation
messages: Periplasm

425104:SSED RS19710
gene id: 425104:SSED_RS19710
uniprot id: A8FZV2
names: Similarity
messages: Belongs to the pirin family.

425104:SSED RS10300
gene id: 425104:SSED_RS10300
uniprot id: A8FUS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

425104:SSED RS17945
gene id: 425104:SSED_RS17945
uniprot id: A8FYW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

425104:SSED RS05130
gene id: 425104:SSED_RS05130
uniprot id: A8FRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

425104:SSED RS12660
gene id: 425104:SSED_RS12660
uniprot id: A8FW04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

425104:SSED RS06340
gene id: 425104:SSED_RS06340
uniprot id: A8FSM1
names: Similarity
messages: Belongs to the GSP E family.

425104:SSED RS01540
gene id: 425104:SSED_RS01540
uniprot id: A8FPY7
names: Subcellular Location Annotation
messages: Periplasm

425104:SSED RS06365
gene id: 425104:SSED_RS06365
uniprot id: A8FSM6
names: Similarity
messages: Belongs to the SUI1 family.

425104:SSED RS18190
gene id: 425104:SSED_RS18190
uniprot id: A8FZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

425104:SSED RS14120
gene id: 425104:SSED_RS14120
uniprot id: A8FWS8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

425104:SSED RS05390
gene id: 425104:SSED_RS05390
uniprot id: A8FS36
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

425104:SSED RS16540
gene id: 425104:SSED_RS16540
uniprot id: A8FY39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

425104:SSED RS03405
gene id: 425104:SSED_RS03405
uniprot id: A8FQZ9
names: Subcellular Location Annotation
messages: Cell outer membrane

425104:SSED RS20865
gene id: 425104:SSED_RS20865
uniprot id: A8G0I1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS23435
gene id: 425104:SSED_RS23435
uniprot id: A8G1W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS12250
gene id: 425104:SSED_RS12250
uniprot id: A8FVS3
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

425104:SSED RS18025
gene id: 425104:SSED_RS18025
uniprot id: A8FYY3
names: Similarity
messages: Belongs to the UPF0162 family.

425104:SSED RS05165
gene id: 425104:SSED_RS05165
uniprot id: A8FRZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

425104:SSED RS19030
gene id: 425104:SSED_RS19030
uniprot id: A8FZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS11120
gene id: 425104:SSED_RS11120
uniprot id: A8FV64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

425104:SSED RS17820
gene id: 425104:SSED_RS17820
uniprot id: A8FYU0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

425104:SSED RS04285
gene id: 425104:SSED_RS04285
uniprot id: A8FRG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

425104:SSED RS08375
gene id: 425104:SSED_RS08375
uniprot id: A8FTQ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS06605
gene id: 425104:SSED_RS06605
uniprot id: A8FSS4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

425104:SSED RS10845
gene id: 425104:SSED_RS10845
uniprot id: A8FV17
names: Similarity
messages: Belongs to the CobH/CbiC family.

425104:SSED RS22445
gene id: 425104:SSED_RS22445
uniprot id: A8G1D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

425104:SSED RS20785
gene id: 425104:SSED_RS20785
uniprot id: A8G0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

425104:SSED RS17980
gene id: 425104:SSED_RS17980
uniprot id: A8FYX4
names: Similarity
messages: Belongs to the UPF0234 family.

425104:SSED RS04195
gene id: 425104:SSED_RS04195
uniprot id: A8FRF1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

425104:SSED RS00330
gene id: 425104:SSED_RS00330
uniprot id: A8FPA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

425104:SSED RS15980
gene id: 425104:SSED_RS15980
uniprot id: A8FXT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

425104:SSED RS17695
gene id: 425104:SSED_RS17695
uniprot id: A8FYR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

425104:SSED RS21750
gene id: 425104:SSED_RS21750
uniprot id: A8G101
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

425104:SSED RS09595
gene id: 425104:SSED_RS09595
uniprot id: A8FUE1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

425104:SSED RS22230
gene id: 425104:SSED_RS22230
uniprot id: A8G196
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS01640
gene id: 425104:SSED_RS01640
uniprot id: A8FQ07
names: Subunit
messages: Monomer.

425104:SSED RS07005
gene id: 425104:SSED_RS07005
uniprot id: A8FSZ1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS13840
gene id: 425104:SSED_RS13840
uniprot id: A8FWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

425104:SSED RS18380
gene id: 425104:SSED_RS18380
uniprot id: A8FZ40
names: Similarity
messages: Belongs to the peptidase M13 family.

425104:SSED RS03800
gene id: 425104:SSED_RS03800
uniprot id: A8FR77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

425104:SSED RS19450
gene id: 425104:SSED_RS19450
uniprot id: A8FZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

425104:SSED RS13150
gene id: 425104:SSED_RS13150
uniprot id: A8FW89
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS22190
gene id: 425104:SSED_RS22190
uniprot id: A8G188
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS14320
gene id: 425104:SSED_RS14320
uniprot id: A8FWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

425104:SSED RS09825
gene id: 425104:SSED_RS09825
uniprot id: A8FUH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

425104:SSED RS07015
gene id: 425104:SSED_RS07015
uniprot id: A8FSZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

425104:SSED RS04890
gene id: 425104:SSED_RS04890
uniprot id: A8FRT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

425104:SSED RS20365
gene id: 425104:SSED_RS20365
uniprot id: A8G081
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

425104:SSED RS19655
gene id: 425104:SSED_RS19655
uniprot id: A8FZU1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

425104:SSED RS14280
gene id: 425104:SSED_RS14280
uniprot id: A8FWW3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

425104:SSED RS15025
gene id: 425104:SSED_RS15025
uniprot id: A8FXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS17515
gene id: 425104:SSED_RS17515
uniprot id: A8FYN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

425104:SSED RS01365
gene id: 425104:SSED_RS01365
uniprot id: A8FPV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

425104:SSED RS21360
gene id: 425104:SSED_RS21360
uniprot id: A8G0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

425104:SSED RS04240
gene id: 425104:SSED_RS04240
uniprot id: A8FRF9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

425104:SSED RS22755
gene id: 425104:SSED_RS22755
uniprot id: A8G1I8
names: Similarity
messages: Belongs to the GSP C family.

425104:SSED RS20725
gene id: 425104:SSED_RS20725
uniprot id: A8G0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

425104:SSED RS08830
gene id: 425104:SSED_RS08830
uniprot id: A8FTZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

425104:SSED RS04015
gene id: 425104:SSED_RS04015
uniprot id: A8FRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

425104:SSED RS18985
gene id: 425104:SSED_RS18985
uniprot id: A8FZG0
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

425104:SSED RS18180
gene id: 425104:SSED_RS18180
uniprot id: A8FZ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS12310
gene id: 425104:SSED_RS12310
uniprot id: A8FVT5
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

425104:SSED RS07720
gene id: 425104:SSED_RS07720
uniprot id: A8FTC9
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

425104:SSED RS06555
gene id: 425104:SSED_RS06555
uniprot id: A8FSR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

425104:SSED RS14015
gene id: 425104:SSED_RS14015
uniprot id: A8FWQ7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS18345
gene id: 425104:SSED_RS18345
uniprot id: A8FZ33
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS19365
gene id: 425104:SSED_RS19365
uniprot id: A8FZN7
names: Similarity
messages: Belongs to the universal stress protein A family.

425104:SSED RS06180
gene id: 425104:SSED_RS06180
uniprot id: A8FSJ4
names: Similarity
messages: Belongs to the P(II) protein family.

425104:SSED RS06550
gene id: 425104:SSED_RS06550
uniprot id: A8FSR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

425104:SSED RS08635
gene id: 425104:SSED_RS08635
uniprot id: A8FTV7
names: Similarity
messages: Belongs to the YciI family.

425104:SSED RS11160
gene id: 425104:SSED_RS11160
uniprot id: A8FV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

425104:SSED RS15160
gene id: 425104:SSED_RS15160
uniprot id: A8FXD9
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS14525
gene id: 425104:SSED_RS14525
uniprot id: A8FX10
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

425104:SSED RS03540
gene id: 425104:SSED_RS03540
uniprot id: A8FR27
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS19600
gene id: 425104:SSED_RS19600
uniprot id: A8FZT0
names: Similarity
messages: Belongs to the peptidase S1B family.

425104:SSED RS01820
gene id: 425104:SSED_RS01820
uniprot id: A8FQ43
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS14970
gene id: 425104:SSED_RS14970
uniprot id: A8FXA0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

425104:SSED RS22550
gene id: 425104:SSED_RS22550
uniprot id: A8G1F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

425104:SSED RS06775
gene id: 425104:SSED_RS06775
uniprot id: A8FSV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

425104:SSED RS01240
gene id: 425104:SSED_RS01240
uniprot id: A8FPT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

425104:SSED RS18200
gene id: 425104:SSED_RS18200
uniprot id: A8FZ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

425104:SSED RS20305
gene id: 425104:SSED_RS20305
uniprot id: A8G069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS22460
gene id: 425104:SSED_RS22460
uniprot id: A8G1D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

425104:SSED RS09565
gene id: 425104:SSED_RS09565
uniprot id: A8FUD5
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS04765
gene id: 425104:SSED_RS04765
uniprot id: A8FRR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

425104:SSED RS20940
gene id: 425104:SSED_RS20940
uniprot id: A8G0J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

425104:SSED RS17810
gene id: 425104:SSED_RS17810
uniprot id: A8FYT8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

425104:SSED RS19925
gene id: 425104:SSED_RS19925
uniprot id: A8FZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

425104:SSED RS10455
gene id: 425104:SSED_RS10455
uniprot id: A8FUV0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS09380
gene id: 425104:SSED_RS09380
uniprot id: A8FU99
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

425104:SSED RS16140
gene id: 425104:SSED_RS16140
uniprot id: A8FXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

425104:SSED RS17675
gene id: 425104:SSED_RS17675
uniprot id: A8FYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

425104:SSED RS01920
gene id: 425104:SSED_RS01920
uniprot id: A8FQ63
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

425104:SSED RS16480
gene id: 425104:SSED_RS16480
uniprot id: A8FY27
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS06670
gene id: 425104:SSED_RS06670
uniprot id: A8FST7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

425104:SSED RS08870
gene id: 425104:SSED_RS08870
uniprot id: A8FU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS20470
gene id: 425104:SSED_RS20470
uniprot id: A8G0A2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS19510
gene id: 425104:SSED_RS19510
uniprot id: A8FZR3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

425104:SSED RS20635
gene id: 425104:SSED_RS20635
uniprot id: A8G0D5
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS03585
gene id: 425104:SSED_RS03585
uniprot id: A8FR36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS01645
gene id: 425104:SSED_RS01645
uniprot id: A8FQ08
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

425104:SSED RS18225
gene id: 425104:SSED_RS18225
uniprot id: A8FZ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

425104:SSED RS22370
gene id: 425104:SSED_RS22370
uniprot id: A8G1C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

425104:SSED RS20895
gene id: 425104:SSED_RS20895
uniprot id: A8G0I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

425104:SSED RS16150
gene id: 425104:SSED_RS16150
uniprot id: A8FXW4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

425104:SSED RS03310
gene id: 425104:SSED_RS03310
uniprot id: A8FQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

425104:SSED RS06720
gene id: 425104:SSED_RS06720
uniprot id: A8FSU6
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

425104:SSED RS20970
gene id: 425104:SSED_RS20970
uniprot id: A8G0K2
names: Similarity
messages: Belongs to the aldose epimerase family.

425104:SSED RS02085
gene id: 425104:SSED_RS02085
uniprot id: A8FQ96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

425104:SSED RS12530
gene id: 425104:SSED_RS12530
uniprot id: A8FVX7
names: Similarity
messages: Belongs to the DEAD box helicase family.

425104:SSED RS08710
gene id: 425104:SSED_RS08710
uniprot id: A8FTX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS07520
gene id: 425104:SSED_RS07520
uniprot id: A8FT90
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

425104:SSED RS13820
gene id: 425104:SSED_RS13820
uniprot id: A8FWL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

425104:SSED RS00015
gene id: 425104:SSED_RS00015
uniprot id: A8FP41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

425104:SSED RS13330
gene id: 425104:SSED_RS13330
uniprot id: A8FWC2
names: Similarity
messages: Belongs to the RutC family.

425104:SSED RS16045
gene id: 425104:SSED_RS16045
uniprot id: A8FXU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

425104:SSED RS07945
gene id: 425104:SSED_RS07945
uniprot id: A8FTH2
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS18910
gene id: 425104:SSED_RS18910
uniprot id: A8FZE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS01005
gene id: 425104:SSED_RS01005
uniprot id: A8FPN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

425104:SSED RS00340
gene id: 425104:SSED_RS00340
uniprot id: A8FPA4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

425104:SSED RS06110
gene id: 425104:SSED_RS06110
uniprot id: A8FSH9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

425104:SSED RS09605
gene id: 425104:SSED_RS09605
uniprot id: A8FUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

425104:SSED RS00130
gene id: 425104:SSED_RS00130
uniprot id: A8FP66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

425104:SSED RS04355
gene id: 425104:SSED_RS04355
uniprot id: A8FRI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.

425104:SSED RS05895
gene id: 425104:SSED_RS05895
uniprot id: A8FSD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

425104:SSED RS00815
gene id: 425104:SSED_RS00815
uniprot id: A8FPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

425104:SSED RS19705
gene id: 425104:SSED_RS19705
uniprot id: A8FZV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS00085
gene id: 425104:SSED_RS00085
uniprot id: A8FP57
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS13155
gene id: 425104:SSED_RS13155
uniprot id: A8FW90
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

425104:SSED RS00940
gene id: 425104:SSED_RS00940
uniprot id: A8FPM2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

425104:SSED RS22020
gene id: 425104:SSED_RS22020
uniprot id: A8G156
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

425104:SSED RS19405
gene id: 425104:SSED_RS19405
uniprot id: A8FZP4
names: Similarity
messages: Belongs to the universal stress protein A family.

425104:SSED RS08565
gene id: 425104:SSED_RS08565
uniprot id: A8FTU3
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00995
gene id: 425104:SSED_RS00995
uniprot id: A8FPN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

425104:SSED RS12090
gene id: 425104:SSED_RS12090
uniprot id: A8FVP2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

425104:SSED RS17905
gene id: 425104:SSED_RS17905
uniprot id: A8FYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS05370
gene id: 425104:SSED_RS05370
uniprot id: A8FS32
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

425104:SSED RS22455
gene id: 425104:SSED_RS22455
uniprot id: A8G1D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

425104:SSED RS12260
gene id: 425104:SSED_RS12260
uniprot id: A8FVS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

425104:SSED RS06335
gene id: 425104:SSED_RS06335
uniprot id: A8FSM0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

425104:SSED RS03985
gene id: 425104:SSED_RS03985
uniprot id: A8FRB3
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

425104:SSED RS19785
gene id: 425104:SSED_RS19785
uniprot id: A8FZW6
names: Similarity
messages: Belongs to the nitroreductase family.

425104:SSED RS17790
gene id: 425104:SSED_RS17790
uniprot id: A8FYT4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS17715
gene id: 425104:SSED_RS17715
uniprot id: A8FYS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

425104:SSED RS11695
gene id: 425104:SSED_RS11695
uniprot id: A8FVG4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

425104:SSED RS05880
gene id: 425104:SSED_RS05880
uniprot id: A8FSD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

425104:SSED RS08845
gene id: 425104:SSED_RS08845
uniprot id: A8FTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

425104:SSED RS05800
gene id: 425104:SSED_RS05800
uniprot id: A8FSB7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS16110
gene id: 425104:SSED_RS16110
uniprot id: A8FXV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

425104:SSED RS10100
gene id: 425104:SSED_RS10100
uniprot id: A8FUN2
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

425104:SSED RS03740
gene id: 425104:SSED_RS03740
uniprot id: A8FR65
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

425104:SSED RS16520
gene id: 425104:SSED_RS16520
uniprot id: A8FY35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

425104:SSED RS13680
gene id: 425104:SSED_RS13680
uniprot id: A8FWJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

425104:SSED RS22700
gene id: 425104:SSED_RS22700
uniprot id: A8G1H7
names: Similarity
messages: Belongs to the GSP N family.

425104:SSED RS06580
gene id: 425104:SSED_RS06580
uniprot id: A8FSR9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

425104:SSED RS08925
gene id: 425104:SSED_RS08925
uniprot id: A8FU15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS22400
gene id: 425104:SSED_RS22400
uniprot id: A8G1C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

425104:SSED RS23640
gene id: 425104:SSED_RS23640
uniprot id: A8FV37
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS23340
gene id: 425104:SSED_RS23340
uniprot id: A8G1V1
names: Similarity
messages: Belongs to the peptidase S41A family.

425104:SSED RS06460
gene id: 425104:SSED_RS06460
uniprot id: A8FSP5
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS04060
gene id: 425104:SSED_RS04060
uniprot id: A8FRC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

425104:SSED RS16515
gene id: 425104:SSED_RS16515
uniprot id: A8FY34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

425104:SSED RS02915
gene id: 425104:SSED_RS02915
uniprot id: A8FQP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

425104:SSED RS15990
gene id: 425104:SSED_RS15990
uniprot id: A8FXT2
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

425104:SSED RS08105
gene id: 425104:SSED_RS08105
uniprot id: A8FTK1
names: Similarity
messages: Belongs to the UPF0319 family.

425104:SSED RS03720
gene id: 425104:SSED_RS03720
uniprot id: A8FR61
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

425104:SSED RS17250
gene id: 425104:SSED_RS17250
uniprot id: A8FYH9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

425104:SSED RS04260
gene id: 425104:SSED_RS04260
uniprot id: A8FRG3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

425104:SSED RS16190
gene id: 425104:SSED_RS16190
uniprot id: A8FXX2
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

425104:SSED RS04515
gene id: 425104:SSED_RS04515
uniprot id: A8FRL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS00975
gene id: 425104:SSED_RS00975
uniprot id: A8FPM9
names: Similarity
messages: Belongs to the SCO1/2 family.

425104:SSED RS18245
gene id: 425104:SSED_RS18245
uniprot id: A8FZ19
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

425104:SSED RS22330
gene id: 425104:SSED_RS22330
uniprot id: A8G1B3
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

425104:SSED RS13240
gene id: 425104:SSED_RS13240
uniprot id: A8FWA5
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

425104:SSED RS17555
gene id: 425104:SSED_RS17555
uniprot id: A8FYP0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS21580
gene id: 425104:SSED_RS21580
uniprot id: A8G0X3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

425104:SSED RS10800
gene id: 425104:SSED_RS10800
uniprot id: A8FV08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

425104:SSED RS12045
gene id: 425104:SSED_RS12045
uniprot id: A8FVN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

425104:SSED RS16165
gene id: 425104:SSED_RS16165
uniprot id: A8FXW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

425104:SSED RS12330
gene id: 425104:SSED_RS12330
uniprot id: A8FVT9
names: Cofactor
messages: Can also use Mn(2+) ion.

425104:SSED RS05205
gene id: 425104:SSED_RS05205
uniprot id: A8FS00
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS17560
gene id: 425104:SSED_RS17560
uniprot id: A8FYP1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Exported by the Tat system.
messages: Periplasm
messages: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

425104:SSED RS22185
gene id: 425104:SSED_RS22185
uniprot id: A8G187
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS10370
gene id: 425104:SSED_RS10370
uniprot id: A8FUT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS20705
gene id: 425104:SSED_RS20705
uniprot id: A8G0E9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS23490
gene id: 425104:SSED_RS23490
uniprot id: A8G1X3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

425104:SSED RS16065
gene id: 425104:SSED_RS16065
uniprot id: A8FXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

425104:SSED RS02975
gene id: 425104:SSED_RS02975
uniprot id: A8FQQ9
names: Similarity
messages: Belongs to the intimin/invasin family.

425104:SSED RS08315
gene id: 425104:SSED_RS08315
uniprot id: A8FTP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

425104:SSED RS06285
gene id: 425104:SSED_RS06285
uniprot id: A8FSL0
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

425104:SSED RS21780
gene id: 425104:SSED_RS21780
uniprot id: A8G107
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

425104:SSED RS18860
gene id: 425104:SSED_RS18860
uniprot id: A8FZD5
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS19870
gene id: 425104:SSED_RS19870
uniprot id: A8FZY3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

425104:SSED RS14695
gene id: 425104:SSED_RS14695
uniprot id: A8FX45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

425104:SSED RS00430
gene id: 425104:SSED_RS00430
uniprot id: A8FPC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

425104:SSED RS14380
gene id: 425104:SSED_RS14380
uniprot id: A8FWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

425104:SSED RS15085
gene id: 425104:SSED_RS15085
uniprot id: A8FXC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

425104:SSED RS18495
gene id: 425104:SSED_RS18495
uniprot id: A8FZ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

425104:SSED RS00020
gene id: 425104:SSED_RS00020
uniprot id: A8FP42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

425104:SSED RS06905
gene id: 425104:SSED_RS06905
uniprot id: A8FSX1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

425104:SSED RS07010
gene id: 425104:SSED_RS07010
uniprot id: A8FSZ2
names: Similarity
messages: Belongs to the hemerythrin family.

425104:SSED RS04670
gene id: 425104:SSED_RS04670
uniprot id: A8FRP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

425104:SSED RS01800
gene id: 425104:SSED_RS01800
uniprot id: A8FQ39
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

425104:SSED RS08695
gene id: 425104:SSED_RS08695
uniprot id: A8FTW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

425104:SSED RS05530
gene id: 425104:SSED_RS05530
uniprot id: A8FS63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

425104:SSED RS10590
gene id: 425104:SSED_RS10590
uniprot id: A8FUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

425104:SSED RS03185
gene id: 425104:SSED_RS03185
uniprot id: A8FQV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

425104:SSED RS22985
gene id: 425104:SSED_RS22985
uniprot id: A8G1N3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS23520
gene id: 425104:SSED_RS23520
uniprot id: A8G1X9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS19005
gene id: 425104:SSED_RS19005
uniprot id: A8FZG4
names: Similarity
messages: Belongs to the peptidase M13 family.

425104:SSED RS11750
gene id: 425104:SSED_RS11750
uniprot id: A8FVH5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

425104:SSED RS20910
gene id: 425104:SSED_RS20910
uniprot id: A8G0J0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

425104:SSED RS06910
gene id: 425104:SSED_RS06910
uniprot id: A8FSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

425104:SSED RS13750
gene id: 425104:SSED_RS13750
uniprot id: A8FWK4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

425104:SSED RS05825
gene id: 425104:SSED_RS05825
uniprot id: A8FSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

425104:SSED RS00125
gene id: 425104:SSED_RS00125
uniprot id: A8FP65
names: Similarity
messages: Belongs to the IMPACT family.

425104:SSED RS10520
gene id: 425104:SSED_RS10520
uniprot id: A8FUW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

425104:SSED RS10765
gene id: 425104:SSED_RS10765
uniprot id: A8FV01
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS19895
gene id: 425104:SSED_RS19895
uniprot id: A8FZY8
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

425104:SSED RS11080
gene id: 425104:SSED_RS11080
uniprot id: A8FV56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS11275
gene id: 425104:SSED_RS11275
uniprot id: A8FV93
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

425104:SSED RS14085
gene id: 425104:SSED_RS14085
uniprot id: A8FWS1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

425104:SSED RS09815
gene id: 425104:SSED_RS09815
uniprot id: A8FUH4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

425104:SSED RS19890
gene id: 425104:SSED_RS19890
uniprot id: A8FZY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

425104:SSED RS09070
gene id: 425104:SSED_RS09070
uniprot id: A8FU44
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

425104:SSED RS16530
gene id: 425104:SSED_RS16530
uniprot id: A8FY37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

425104:SSED RS08480
gene id: 425104:SSED_RS08480
uniprot id: A8FTS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

425104:SSED RS22760
gene id: 425104:SSED_RS22760
uniprot id: A8G1I9
names: Similarity
messages: Belongs to the HSP15 family.

425104:SSED RS05450
gene id: 425104:SSED_RS05450
uniprot id: A8FS48
names: Similarity
messages: Belongs to the glutamine synthetase family.

425104:SSED RS02325
gene id: 425104:SSED_RS02325
uniprot id: A8FQD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS22065
gene id: 425104:SSED_RS22065
uniprot id: A8G165
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

425104:SSED RS07630
gene id: 425104:SSED_RS07630
uniprot id: A8FTB1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

425104:SSED RS16125
gene id: 425104:SSED_RS16125
uniprot id: A8FXV9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

425104:SSED RS09810
gene id: 425104:SSED_RS09810
uniprot id: A8FUH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

425104:SSED RS15115
gene id: 425104:SSED_RS15115
uniprot id: A8FXD0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

425104:SSED RS17580
gene id: 425104:SSED_RS17580
uniprot id: A8FYP5
names: Similarity
messages: Belongs to the DEAD box helicase family.

425104:SSED RS12790
gene id: 425104:SSED_RS12790
uniprot id: A8FW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

425104:SSED RS22490
gene id: 425104:SSED_RS22490
uniprot id: A8G1E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

425104:SSED RS05665
gene id: 425104:SSED_RS05665
uniprot id: A8FS90
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

425104:SSED RS01765
gene id: 425104:SSED_RS01765
uniprot id: A8FQ32
names: Subcellular Location Annotation
messages: Periplasm

425104:SSED RS06640
gene id: 425104:SSED_RS06640
uniprot id: A8FST1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

425104:SSED RS08025
gene id: 425104:SSED_RS08025
uniprot id: A8FTI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

425104:SSED RS21145
gene id: 425104:SSED_RS21145
uniprot id: A8G0N7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS02125
gene id: 425104:SSED_RS02125
uniprot id: A8FQA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

425104:SSED RS09570
gene id: 425104:SSED_RS09570
uniprot id: A8FUD6
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

425104:SSED RS04820
gene id: 425104:SSED_RS04820
uniprot id: A8FRS5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

425104:SSED RS05695
gene id: 425104:SSED_RS05695
uniprot id: A8FS96
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

425104:SSED RS18325
gene id: 425104:SSED_RS18325
uniprot id: A8FZ30
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

425104:SSED RS13905
gene id: 425104:SSED_RS13905
uniprot id: A8FWN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

425104:SSED RS05885
gene id: 425104:SSED_RS05885
uniprot id: A8FSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

425104:SSED RS04005
gene id: 425104:SSED_RS04005
uniprot id: A8FRB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

425104:SSED RS14110
gene id: 425104:SSED_RS14110
uniprot id: A8FWS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

425104:SSED RS00790
gene id: 425104:SSED_RS00790
uniprot id: A8FPJ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS00625
gene id: 425104:SSED_RS00625
uniprot id: A8FPF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

425104:SSED RS00660
gene id: 425104:SSED_RS00660
uniprot id: A8FPG6
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS08745
gene id: 425104:SSED_RS08745
uniprot id: A8FTX9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

425104:SSED RS06125
gene id: 425104:SSED_RS06125
uniprot id: A8FSI2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

425104:SSED RS01130
gene id: 425104:SSED_RS01130
uniprot id: A8FPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

425104:SSED RS05785
gene id: 425104:SSED_RS05785
uniprot id: A8FSB4
names: Similarity
messages: Belongs to the glutamate synthase family.

425104:SSED RS03820
gene id: 425104:SSED_RS03820
uniprot id: A8FR81
names: Similarity
messages: Belongs to the peptidase S1C family.

425104:SSED RS03865
gene id: 425104:SSED_RS03865
uniprot id: A8FR90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

425104:SSED RS17845
gene id: 425104:SSED_RS17845
uniprot id: A8FYU5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

425104:SSED RS04715
gene id: 425104:SSED_RS04715
uniprot id: A8FRQ4
names: Similarity
messages: Belongs to the SlyX family.

425104:SSED RS16465
gene id: 425104:SSED_RS16465
uniprot id: A8FY24
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

425104:SSED RS02070
gene id: 425104:SSED_RS02070
uniprot id: A8FQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

425104:SSED RS21870
gene id: 425104:SSED_RS21870
uniprot id: A8G125
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS14895
gene id: 425104:SSED_RS14895
uniprot id: A8FX84
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

425104:SSED RS13245
gene id: 425104:SSED_RS13245
uniprot id: A8FWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

425104:SSED RS23320
gene id: 425104:SSED_RS23320
uniprot id: A8G1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

425104:SSED RS11580
gene id: 425104:SSED_RS11580
uniprot id: A8FVE7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

425104:SSED RS18595
gene id: 425104:SSED_RS18595
uniprot id: A8FZ83
names: Similarity
messages: Belongs to the glutamate synthase family.

425104:SSED RS22025
gene id: 425104:SSED_RS22025
uniprot id: A8G157
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

425104:SSED RS06650
gene id: 425104:SSED_RS06650
uniprot id: A8FST3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

425104:SSED RS04600
gene id: 425104:SSED_RS04600
uniprot id: A8FRN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

425104:SSED RS06850
gene id: 425104:SSED_RS06850
uniprot id: A8FSW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

425104:SSED RS16340
gene id: 425104:SSED_RS16340
uniprot id: A8FY01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

425104:SSED RS21065
gene id: 425104:SSED_RS21065
uniprot id: A8G0M1
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

425104:SSED RS23045
gene id: 425104:SSED_RS23045
uniprot id: A8G1P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

425104:SSED RS17910
gene id: 425104:SSED_RS17910
uniprot id: A8FYW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS18500
gene id: 425104:SSED_RS18500
uniprot id: A8FZ64
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

425104:SSED RS19845
gene id: 425104:SSED_RS19845
uniprot id: A8FZX8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

425104:SSED RS17315
gene id: 425104:SSED_RS17315
uniprot id: A8FYJ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

425104:SSED RS11010
gene id: 425104:SSED_RS11010
uniprot id: A8FV48
names: Similarity
messages: Belongs to the citrate synthase family.

425104:SSED RS16490
gene id: 425104:SSED_RS16490
uniprot id: A8FY29
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

425104:SSED RS00480
gene id: 425104:SSED_RS00480
uniprot id: A8FPD2
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

425104:SSED RS20195
gene id: 425104:SSED_RS20195
uniprot id: A8G048
names: Similarity
messages: Belongs to the phosphoribulokinase family.

425104:SSED RS04755
gene id: 425104:SSED_RS04755
uniprot id: A8FRR2
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.

425104:SSED RS00590
gene id: 425104:SSED_RS00590
uniprot id: A8FPF2
names: Cofactor
messages: Binds 1 zinc ion per subunit.

425104:SSED RS15905
gene id: 425104:SSED_RS15905
uniprot id: A8FXR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

425104:SSED RS07305
gene id: 425104:SSED_RS07305
uniprot id: A8FT48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

425104:SSED RS04425
gene id: 425104:SSED_RS04425
uniprot id: A8FRJ6
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS13990
gene id: 425104:SSED_RS13990
uniprot id: A8FWQ2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

425104:SSED RS23130
gene id: 425104:SSED_RS23130
uniprot id: A8G1R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

425104:SSED RS08720
gene id: 425104:SSED_RS08720
uniprot id: A8FTX4
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

425104:SSED RS08550
gene id: 425104:SSED_RS08550
uniprot id: A8FTU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

425104:SSED RS08640
gene id: 425104:SSED_RS08640
uniprot id: A8FTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

425104:SSED RS08405
gene id: 425104:SSED_RS08405
uniprot id: A8FTQ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

425104:SSED RS17095
gene id: 425104:SSED_RS17095
uniprot id: A8FYE8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

425104:SSED RS06275
gene id: 425104:SSED_RS06275
uniprot id: A8FSK8
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

425104:SSED RS14705
gene id: 425104:SSED_RS14705
uniprot id: A8FX47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

425104:SSED RS12035
gene id: 425104:SSED_RS12035
uniprot id: A8FVN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

425104:SSED RS00930
gene id: 425104:SSED_RS00930
uniprot id: A8FPM0
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS20360
gene id: 425104:SSED_RS20360
uniprot id: A8G080
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

425104:SSED RS12780
gene id: 425104:SSED_RS12780
uniprot id: A8FW27
names: Similarity
messages: Belongs to the DnaA family.

425104:SSED RS13895
gene id: 425104:SSED_RS13895
uniprot id: A8FWN3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

425104:SSED RS22950
gene id: 425104:SSED_RS22950
uniprot id: A8G1M6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

425104:SSED RS02775
gene id: 425104:SSED_RS02775
uniprot id: A8FQL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

425104:SSED RS14635
gene id: 425104:SSED_RS14635
uniprot id: A8FX33
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

425104:SSED RS03495
gene id: 425104:SSED_RS03495
uniprot id: A8FR18
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

425104:SSED RS12115
gene id: 425104:SSED_RS12115
uniprot id: A8FVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

425104:SSED RS00985
gene id: 425104:SSED_RS00985
uniprot id: A8FPN1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS11020
gene id: 425104:SSED_RS11020
uniprot id: A8FV50
names: Similarity
messages: Belongs to the PrpF family.

425104:SSED RS19935
gene id: 425104:SSED_RS19935
uniprot id: A8FZZ6
names: Similarity
messages: Belongs to the YoeB family.

425104:SSED RS05575
gene id: 425104:SSED_RS05575
uniprot id: A8FS72
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

425104:SSED RS06075
gene id: 425104:SSED_RS06075
uniprot id: A8FSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

425104:SSED RS21525
gene id: 425104:SSED_RS21525
uniprot id: A8G0W2
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

425104:SSED RS09740
gene id: 425104:SSED_RS09740
uniprot id: A8FUF9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

425104:SSED RS10420
gene id: 425104:SSED_RS10420
uniprot id: A8FUU2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

425104:SSED RS18900
gene id: 425104:SSED_RS18900
uniprot id: A8FZE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

425104:SSED RS04315
gene id: 425104:SSED_RS04315
uniprot id: A8FRH4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

425104:SSED RS07415
gene id: 425104:SSED_RS07415
uniprot id: A8FT70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

425104:SSED RS16835
gene id: 425104:SSED_RS16835
uniprot id: A8FY97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

425104:SSED RS19175
gene id: 425104:SSED_RS19175
uniprot id: A8FZJ8
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS03980
gene id: 425104:SSED_RS03980
uniprot id: A8FRB2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

425104:SSED RS11115
gene id: 425104:SSED_RS11115
uniprot id: A8FV63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

425104:SSED RS20035
gene id: 425104:SSED_RS20035
uniprot id: A8G016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

425104:SSED RS16120
gene id: 425104:SSED_RS16120
uniprot id: A8FXV8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

425104:SSED RS05135
gene id: 425104:SSED_RS05135
uniprot id: A8FRY8
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22965
gene id: 425104:SSED_RS22965
uniprot id: A8G1M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

425104:SSED RS06765
gene id: 425104:SSED_RS06765
uniprot id: A8FSV5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS13740
gene id: 425104:SSED_RS13740
uniprot id: A8FWK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

425104:SSED RS12105
gene id: 425104:SSED_RS12105
uniprot id: A8FVP5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS05545
gene id: 425104:SSED_RS05545
uniprot id: A8FS66
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

425104:SSED RS21715
gene id: 425104:SSED_RS21715
uniprot id: A8G0Z4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

425104:SSED RS22740
gene id: 425104:SSED_RS22740
uniprot id: A8G1I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

425104:SSED RS12075
gene id: 425104:SSED_RS12075
uniprot id: A8FVN9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

425104:SSED RS20770
gene id: 425104:SSED_RS20770
uniprot id: A8G0G2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS18740
gene id: 425104:SSED_RS18740
uniprot id: A8FZB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS03895
gene id: 425104:SSED_RS03895
uniprot id: A8FR95
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

425104:SSED RS13915
gene id: 425104:SSED_RS13915
uniprot id: A8FWN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

425104:SSED RS05900
gene id: 425104:SSED_RS05900
uniprot id: A8FSD8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

425104:SSED RS04905
gene id: 425104:SSED_RS04905
uniprot id: A8FRU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

425104:SSED RS00630
gene id: 425104:SSED_RS00630
uniprot id: A8FPG0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

425104:SSED RS07330
gene id: 425104:SSED_RS07330
uniprot id: A8FT53
names: Cofactor
messages: Can also use Mn(2+) ion.

425104:SSED RS05955
gene id: 425104:SSED_RS05955
uniprot id: A8FSE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

425104:SSED RS15805
gene id: 425104:SSED_RS15805
uniprot id: A8FXP5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

425104:SSED RS04050
gene id: 425104:SSED_RS04050
uniprot id: A8FRC6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

425104:SSED RS08655
gene id: 425104:SSED_RS08655
uniprot id: A8FTW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS22430
gene id: 425104:SSED_RS22430
uniprot id: A8G1D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

425104:SSED RS11230
gene id: 425104:SSED_RS11230
uniprot id: A8FV84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS14590
gene id: 425104:SSED_RS14590
uniprot id: A8FX24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

425104:SSED RS15355
gene id: 425104:SSED_RS15355
uniprot id: A8FXF7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

425104:SSED RS01325
gene id: 425104:SSED_RS01325
uniprot id: A8FPV1
names: Similarity
messages: Belongs to the peptidase M16 family.

425104:SSED RS02025
gene id: 425104:SSED_RS02025
uniprot id: A8FQ84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS21820
gene id: 425104:SSED_RS21820
uniprot id: A8G115
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

425104:SSED RS17990
gene id: 425104:SSED_RS17990
uniprot id: A8FYX6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

425104:SSED RS20495
gene id: 425104:SSED_RS20495
uniprot id: A8G0A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

425104:SSED RS04500
gene id: 425104:SSED_RS04500
uniprot id: A8FRL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

425104:SSED RS16525
gene id: 425104:SSED_RS16525
uniprot id: A8FY36
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

425104:SSED RS18705
gene id: 425104:SSED_RS18705
uniprot id: A8FZA4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

425104:SSED RS12215
gene id: 425104:SSED_RS12215
uniprot id: A8FVR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

425104:SSED RS21020
gene id: 425104:SSED_RS21020
uniprot id: A8G0L2
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

425104:SSED RS00165
gene id: 425104:SSED_RS00165
uniprot id: A8FP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

425104:SSED RS04320
gene id: 425104:SSED_RS04320
uniprot id: A8FRH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

425104:SSED RS02465
gene id: 425104:SSED_RS02465
uniprot id: A8FQF7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

425104:SSED RS00115
gene id: 425104:SSED_RS00115
uniprot id: A8FP63
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

425104:SSED RS12110
gene id: 425104:SSED_RS12110
uniprot id: A8FVP6
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

425104:SSED RS13325
gene id: 425104:SSED_RS13325
uniprot id: A8FWC1
names: Similarity
messages: Belongs to the UPF0597 family.

425104:SSED RS12590
gene id: 425104:SSED_RS12590
uniprot id: A8FVZ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS04650
gene id: 425104:SSED_RS04650
uniprot id: A8FRP1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS06610
gene id: 425104:SSED_RS06610
uniprot id: A8FSS5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

425104:SSED RS20275
gene id: 425104:SSED_RS20275
uniprot id: A8G063
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS12325
gene id: 425104:SSED_RS12325
uniprot id: A8FVT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS13650
gene id: 425104:SSED_RS13650
uniprot id: A8FWI3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS02260
gene id: 425104:SSED_RS02260
uniprot id: A8FQB7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

425104:SSED RS19210
gene id: 425104:SSED_RS19210
uniprot id: A8FZK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

425104:SSED RS21150
gene id: 425104:SSED_RS21150
uniprot id: A8G0N8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

425104:SSED RS00555
gene id: 425104:SSED_RS00555
uniprot id: A8FPE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS07420
gene id: 425104:SSED_RS07420
uniprot id: A8FT71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS17140
gene id: 425104:SSED_RS17140
uniprot id: A8FYF7
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS01775
gene id: 425104:SSED_RS01775
uniprot id: A8FQ34
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

425104:SSED RS05290
gene id: 425104:SSED_RS05290
uniprot id: A8FS17
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS09865
gene id: 425104:SSED_RS09865
uniprot id: A8FUI6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

425104:SSED RS19570
gene id: 425104:SSED_RS19570
uniprot id: A8FZS5
names: Similarity
messages: Belongs to the cytochrome c-552 family.

425104:SSED RS04995
gene id: 425104:SSED_RS04995
uniprot id: A8FRW0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

425104:SSED RS17965
gene id: 425104:SSED_RS17965
uniprot id: A8FYX1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

425104:SSED RS06570
gene id: 425104:SSED_RS06570
uniprot id: A8FSR7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

425104:SSED RS20185
gene id: 425104:SSED_RS20185
uniprot id: A8G046
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

425104:SSED RS05645
gene id: 425104:SSED_RS05645
uniprot id: A8FS86
names: Similarity
messages: Belongs to the alkaline phosphatase family.

425104:SSED RS17775
gene id: 425104:SSED_RS17775
uniprot id: A8FYT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

425104:SSED RS03840
gene id: 425104:SSED_RS03840
uniprot id: A8FR85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

425104:SSED RS08610
gene id: 425104:SSED_RS08610
uniprot id: A8FTV2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS22500
gene id: 425104:SSED_RS22500
uniprot id: A8G1E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

425104:SSED RS16565
gene id: 425104:SSED_RS16565
uniprot id: A8FY44
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

425104:SSED RS01570
gene id: 425104:SSED_RS01570
uniprot id: A8FPZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

425104:SSED RS05480
gene id: 425104:SSED_RS05480
uniprot id: A8FS54
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS18145
gene id: 425104:SSED_RS18145
uniprot id: A8FYZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

425104:SSED RS03245
gene id: 425104:SSED_RS03245
uniprot id: A8FQW5
names: Similarity
messages: Belongs to the PhoH family.

425104:SSED RS17280
gene id: 425104:SSED_RS17280
uniprot id: A8FYI5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

425104:SSED RS02925
gene id: 425104:SSED_RS02925
uniprot id: A8FQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

425104:SSED RS22475
gene id: 425104:SSED_RS22475
uniprot id: A8G1E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

425104:SSED RS01735
gene id: 425104:SSED_RS01735
uniprot id: A8FQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

425104:SSED RS15795
gene id: 425104:SSED_RS15795
uniprot id: A8FXP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

425104:SSED RS19275
gene id: 425104:SSED_RS19275
uniprot id: A8FZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

425104:SSED RS22980
gene id: 425104:SSED_RS22980
uniprot id: A8G1N2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

425104:SSED RS01000
gene id: 425104:SSED_RS01000
uniprot id: A8FPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

425104:SSED RS10200
gene id: 425104:SSED_RS10200
uniprot id: A8FUQ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS13475
gene id: 425104:SSED_RS13475
uniprot id: A8FWE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

425104:SSED RS06760
gene id: 425104:SSED_RS06760
uniprot id: A8FSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS12875
gene id: 425104:SSED_RS12875
uniprot id: A8FW42
names: Similarity
messages: Belongs to the Gfa family.

425104:SSED RS20345
gene id: 425104:SSED_RS20345
uniprot id: A8G077
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

425104:SSED RS01485
gene id: 425104:SSED_RS01485
uniprot id: A8FPX6
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

425104:SSED RS00910
gene id: 425104:SSED_RS00910
uniprot id: A8FPL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

425104:SSED RS03910
gene id: 425104:SSED_RS03910
uniprot id: A8FR98
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

425104:SSED RS19105
gene id: 425104:SSED_RS19105
uniprot id: A8FZI4
names: Similarity
messages: Belongs to the cytochrome c-552 family.

425104:SSED RS01060
gene id: 425104:SSED_RS01060
uniprot id: A8FPP7
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS13380
gene id: 425104:SSED_RS13380
uniprot id: A8FWD2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

425104:SSED RS10535
gene id: 425104:SSED_RS10535
uniprot id: A8FUW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS05540
gene id: 425104:SSED_RS05540
uniprot id: A8FS65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

425104:SSED RS10570
gene id: 425104:SSED_RS10570
uniprot id: A8FUX3
names: Similarity
messages: Belongs to the glyoxalase I family.

425104:SSED RS11850
gene id: 425104:SSED_RS11850
uniprot id: A8FVJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

425104:SSED RS15970
gene id: 425104:SSED_RS15970
uniprot id: A8FXS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

425104:SSED RS02240
gene id: 425104:SSED_RS02240
uniprot id: A8FQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

425104:SSED RS17930
gene id: 425104:SSED_RS17930
uniprot id: A8FYW4
names: Similarity
messages: Belongs to the BolA/IbaG family.

425104:SSED RS05865
gene id: 425104:SSED_RS05865
uniprot id: A8FSD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

425104:SSED RS00850
gene id: 425104:SSED_RS00850
uniprot id: A8FPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

425104:SSED RS22225
gene id: 425104:SSED_RS22225
uniprot id: A8G195
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

425104:SSED RS10480
gene id: 425104:SSED_RS10480
uniprot id: A8FUV5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

425104:SSED RS17080
gene id: 425104:SSED_RS17080
uniprot id: A8FYE5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS22605
gene id: 425104:SSED_RS22605
uniprot id: A8G1G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

425104:SSED RS14770
gene id: 425104:SSED_RS14770
uniprot id: A8FX60
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS07300
gene id: 425104:SSED_RS07300
uniprot id: A8FT47
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

425104:SSED RS05910
gene id: 425104:SSED_RS05910
uniprot id: A8FSE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

425104:SSED RS02550
gene id: 425104:SSED_RS02550
uniprot id: A8FQH4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

425104:SSED RS18465
gene id: 425104:SSED_RS18465
uniprot id: A8FZ57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

425104:SSED RS08060
gene id: 425104:SSED_RS08060
uniprot id: A8FTJ2
names: Similarity
messages: Belongs to the PspA/IM30 family.

425104:SSED RS00120
gene id: 425104:SSED_RS00120
uniprot id: A8FP64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

425104:SSED RS01115
gene id: 425104:SSED_RS01115
uniprot id: A8FPQ8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

425104:SSED RS00350
gene id: 425104:SSED_RS00350
uniprot id: A8FPA6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

425104:SSED RS10415
gene id: 425104:SSED_RS10415
uniprot id: A8FUU1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS18170
gene id: 425104:SSED_RS18170
uniprot id: A8FZ04
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

425104:SSED RS16485
gene id: 425104:SSED_RS16485
uniprot id: A8FY28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

425104:SSED RS02385
gene id: 425104:SSED_RS02385
uniprot id: A8FQE2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS00100
gene id: 425104:SSED_RS00100
uniprot id: A8FP60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

425104:SSED RS09105
gene id: 425104:SSED_RS09105
uniprot id: A8FU51
names: Similarity
messages: Belongs to the proline racemase family.

425104:SSED RS16160
gene id: 425104:SSED_RS16160
uniprot id: A8FXW6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

425104:SSED RS11290
gene id: 425104:SSED_RS11290
uniprot id: A8FV96
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

425104:SSED RS21535
gene id: 425104:SSED_RS21535
uniprot id: A8G0W4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

425104:SSED RS05725
gene id: 425104:SSED_RS05725
uniprot id: A8FSA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Membrane

425104:SSED RS10780
gene id: 425104:SSED_RS10780
uniprot id: A8FV04
names: Similarity
messages: Belongs to the pyruvate kinase family.

425104:SSED RS08595
gene id: 425104:SSED_RS08595
uniprot id: A8FTU9
names: Similarity
messages: Belongs to the peptidase S33 family.

425104:SSED RS15545
gene id: 425104:SSED_RS15545
uniprot id: A8FXJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

425104:SSED RS09800
gene id: 425104:SSED_RS09800
uniprot id: A8FUH1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

425104:SSED RS18140
gene id: 425104:SSED_RS18140
uniprot id: A8FYZ8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

425104:SSED RS04135
gene id: 425104:SSED_RS04135
uniprot id: A8FRD9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

425104:SSED RS03000
gene id: 425104:SSED_RS03000
uniprot id: A8FQR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

425104:SSED RS12005
gene id: 425104:SSED_RS12005
uniprot id: A8FVM4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

425104:SSED RS01150
gene id: 425104:SSED_RS01150
uniprot id: A8FPR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

425104:SSED RS08305
gene id: 425104:SSED_RS08305
uniprot id: A8FTN9
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

425104:SSED RS16360
gene id: 425104:SSED_RS16360
uniprot id: A8FY04
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

425104:SSED RS14700
gene id: 425104:SSED_RS14700
uniprot id: A8FX46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

425104:SSED RS02410
gene id: 425104:SSED_RS02410
uniprot id: A8FQE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

425104:SSED RS04040
gene id: 425104:SSED_RS04040
uniprot id: A8FRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

425104:SSED RS13295
gene id: 425104:SSED_RS13295
uniprot id: A8FWB6
names: Similarity
messages: Belongs to the glutamine synthetase family.

425104:SSED RS14845
gene id: 425104:SSED_RS14845
uniprot id: A8FX75
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

425104:SSED RS11325
gene id: 425104:SSED_RS11325
uniprot id: A8FVA3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS05520
gene id: 425104:SSED_RS05520
uniprot id: A8FS61
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

425104:SSED RS18515
gene id: 425104:SSED_RS18515
uniprot id: A8FZ67
names: Function
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons.

425104:SSED RS01135
gene id: 425104:SSED_RS01135
uniprot id: A8FPR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

425104:SSED RS05590
gene id: 425104:SSED_RS05590
uniprot id: A8FS75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

425104:SSED RS20555
gene id: 425104:SSED_RS20555
uniprot id: A8G0B9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS21365
gene id: 425104:SSED_RS21365
uniprot id: A8G0T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

425104:SSED RS06310
gene id: 425104:SSED_RS06310
uniprot id: A8FSL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

425104:SSED RS06665
gene id: 425104:SSED_RS06665
uniprot id: A8FST6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

425104:SSED RS08090
gene id: 425104:SSED_RS08090
uniprot id: A8FTJ8
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS06305
gene id: 425104:SSED_RS06305
uniprot id: A8FSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

425104:SSED RS12290
gene id: 425104:SSED_RS12290
uniprot id: A8FVT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS14775
gene id: 425104:SSED_RS14775
uniprot id: A8FX61
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS04510
gene id: 425104:SSED_RS04510
uniprot id: A8FRL3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

425104:SSED RS00040
gene id: 425104:SSED_RS00040
uniprot id: A8FP48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

425104:SSED RS21330
gene id: 425104:SSED_RS21330
uniprot id: A8G0S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

425104:SSED RS02390
gene id: 425104:SSED_RS02390
uniprot id: A8FQE3
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS01035
gene id: 425104:SSED_RS01035
uniprot id: A8FPP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

425104:SSED RS17890
gene id: 425104:SSED_RS17890
uniprot id: A8FYV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

425104:SSED RS19580
gene id: 425104:SSED_RS19580
uniprot id: A8FZS7
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

425104:SSED RS04785
gene id: 425104:SSED_RS04785
uniprot id: A8FRR8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS12855
gene id: 425104:SSED_RS12855
uniprot id: A8FW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

425104:SSED RS05245
gene id: 425104:SSED_RS05245
uniprot id: A8FS08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

425104:SSED RS18745
gene id: 425104:SSED_RS18745
uniprot id: A8FZB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

425104:SSED RS03920
gene id: 425104:SSED_RS03920
uniprot id: A8FRA0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

425104:SSED RS13200
gene id: 425104:SSED_RS13200
uniprot id: A8FW97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

425104:SSED RS02075
gene id: 425104:SSED_RS02075
uniprot id: A8FQ94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

425104:SSED RS22215
gene id: 425104:SSED_RS22215
uniprot id: A8G193
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

425104:SSED RS14225
gene id: 425104:SSED_RS14225
uniprot id: A8FWV0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

425104:SSED RS16775
gene id: 425104:SSED_RS16775
uniprot id: A8FY85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS12230
gene id: 425104:SSED_RS12230
uniprot id: A8FVR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

425104:SSED RS19220
gene id: 425104:SSED_RS19220
uniprot id: A8FZK7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

425104:SSED RS01355
gene id: 425104:SSED_RS01355
uniprot id: A8FPV7
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

425104:SSED RS23440
gene id: 425104:SSED_RS23440
uniprot id: A8G1W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

425104:SSED RS02095
gene id: 425104:SSED_RS02095
uniprot id: A8FQ98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

425104:SSED RS08070
gene id: 425104:SSED_RS08070
uniprot id: A8FTJ4
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22650
gene id: 425104:SSED_RS22650
uniprot id: A8G1G7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

425104:SSED RS18255
gene id: 425104:SSED_RS18255
uniprot id: A8FZ21
names: Similarity
messages: Belongs to the UPF0250 family.

425104:SSED RS00405
gene id: 425104:SSED_RS00405
uniprot id: A8FPB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

425104:SSED RS16920
gene id: 425104:SSED_RS16920
uniprot id: A8FYB4
names: Function
messages: Could be a 3Fe-4S cluster-containing protein.

425104:SSED RS12860
gene id: 425104:SSED_RS12860
uniprot id: A8FW40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

425104:SSED RS07500
gene id: 425104:SSED_RS07500
uniprot id: A8FT86
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

425104:SSED RS20140
gene id: 425104:SSED_RS20140
uniprot id: A8G037
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

425104:SSED RS15090
gene id: 425104:SSED_RS15090
uniprot id: A8FXC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

425104:SSED RS23450
gene id: 425104:SSED_RS23450
uniprot id: A8G1W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

425104:SSED RS16035
gene id: 425104:SSED_RS16035
uniprot id: A8FXU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

425104:SSED RS01015
gene id: 425104:SSED_RS01015
uniprot id: A8FPN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

425104:SSED RS20915
gene id: 425104:SSED_RS20915
uniprot id: A8G0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

425104:SSED RS03570
gene id: 425104:SSED_RS03570
uniprot id: A8FR33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

425104:SSED RS09875
gene id: 425104:SSED_RS09875
uniprot id: A8FUI8
names: Similarity
messages: Belongs to the HypD family.

425104:SSED RS23410
gene id: 425104:SSED_RS23410
uniprot id: A8G1V7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS22340
gene id: 425104:SSED_RS22340
uniprot id: A8G1B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS22545
gene id: 425104:SSED_RS22545
uniprot id: A8G1F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

425104:SSED RS21710
gene id: 425104:SSED_RS21710
uniprot id: A8G0Z3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

425104:SSED RS09555
gene id: 425104:SSED_RS09555
uniprot id: A8FUD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

425104:SSED RS10665
gene id: 425104:SSED_RS10665
uniprot id: A8FUY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS12795
gene id: 425104:SSED_RS12795
uniprot id: A8FW30
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

425104:SSED RS02565
gene id: 425104:SSED_RS02565
uniprot id: A8FQH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

425104:SSED RS18260
gene id: 425104:SSED_RS18260
uniprot id: A8FZ22
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

425104:SSED RS15290
gene id: 425104:SSED_RS15290
uniprot id: A8FXE4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

425104:SSED RS02865
gene id: 425104:SSED_RS02865
uniprot id: A8FQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

425104:SSED RS22260
gene id: 425104:SSED_RS22260
uniprot id: A8G1A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

425104:SSED RS02355
gene id: 425104:SSED_RS02355
uniprot id: A8FQD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

425104:SSED RS05465
gene id: 425104:SSED_RS05465
uniprot id: A8FS51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

425104:SSED RS00530
gene id: 425104:SSED_RS00530
uniprot id: A8FPE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

425104:SSED RS19500
gene id: 425104:SSED_RS19500
uniprot id: A8FZR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

425104:SSED RS11710
gene id: 425104:SSED_RS11710
uniprot id: A8FVG7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

425104:SSED RS11135
gene id: 425104:SSED_RS11135
uniprot id: A8FV67
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

425104:SSED RS16445
gene id: 425104:SSED_RS16445
uniprot id: A8FY20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

425104:SSED RS12060
gene id: 425104:SSED_RS12060
uniprot id: A8FVN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

425104:SSED RS11385
gene id: 425104:SSED_RS11385
uniprot id: A8FVB5
names: Similarity
messages: Belongs to the universal stress protein A family.

425104:SSED RS13890
gene id: 425104:SSED_RS13890
uniprot id: A8FWN2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

425104:SSED RS17410
gene id: 425104:SSED_RS17410
uniprot id: A8FYL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

425104:SSED RS12440
gene id: 425104:SSED_RS12440
uniprot id: A8FVW0
names: Similarity
messages: Belongs to the peptidase A24 family.

425104:SSED RS00490
gene id: 425104:SSED_RS00490
uniprot id: A8FPD4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

425104:SSED RS00035
gene id: 425104:SSED_RS00035
uniprot id: A8FP47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

425104:SSED RS22525
gene id: 425104:SSED_RS22525
uniprot id: A8G1F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

425104:SSED RS00740
gene id: 425104:SSED_RS00740
uniprot id: A8FPI2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

425104:SSED RS07765
gene id: 425104:SSED_RS07765
uniprot id: A8FTD8
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS05950
gene id: 425104:SSED_RS05950
uniprot id: A8FSE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

425104:SSED RS02250
gene id: 425104:SSED_RS02250
uniprot id: A8FQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

425104:SSED RS17040
gene id: 425104:SSED_RS17040
uniprot id: A8FYD7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS07480
gene id: 425104:SSED_RS07480
uniprot id: A8FT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

425104:SSED RS12640
gene id: 425104:SSED_RS12640
uniprot id: A8FW00
names: Subcellular Location Annotation
messages: Cytoplasm

425104:SSED RS12050
gene id: 425104:SSED_RS12050
uniprot id: A8FVN4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

425104:SSED RS00305
gene id: 425104:SSED_RS00305
uniprot id: A8FP97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

425104:SSED RS09830
gene id: 425104:SSED_RS09830
uniprot id: A8FUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

425104:SSED RS01350
gene id: 425104:SSED_RS01350
uniprot id: A8FPV6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS12720
gene id: 425104:SSED_RS12720
uniprot id: A8FW15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

425104:SSED RS21655
gene id: 425104:SSED_RS21655
uniprot id: A8G0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

425104:SSED RS11300
gene id: 425104:SSED_RS11300
uniprot id: A8FV98
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

425104:SSED RS03440
gene id: 425104:SSED_RS03440
uniprot id: A8FR06
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS00980
gene id: 425104:SSED_RS00980
uniprot id: A8FPN0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

425104:SSED RS21180
gene id: 425104:SSED_RS21180
uniprot id: A8G0P5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS00175
gene id: 425104:SSED_RS00175
uniprot id: A8FP75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

425104:SSED RS12685
gene id: 425104:SSED_RS12685
uniprot id: A8FW08
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

425104:SSED RS03445
gene id: 425104:SSED_RS03445
uniprot id: A8FR08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS00030
gene id: 425104:SSED_RS00030
uniprot id: A8FP46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

425104:SSED RS11630
gene id: 425104:SSED_RS11630
uniprot id: A8FVF7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

425104:SSED RS09790
gene id: 425104:SSED_RS09790
uniprot id: A8FUG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

425104:SSED RS08700
gene id: 425104:SSED_RS08700
uniprot id: A8FTX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

425104:SSED RS04175
gene id: 425104:SSED_RS04175
uniprot id: A8FRE7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

425104:SSED RS14820
gene id: 425104:SSED_RS14820
uniprot id: A8FX70
names: Similarity
messages: Belongs to the UPF0227 family.

425104:SSED RS21340
gene id: 425104:SSED_RS21340
uniprot id: A8G0S7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

425104:SSED RS05960
gene id: 425104:SSED_RS05960
uniprot id: A8FSE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

425104:SSED RS17975
gene id: 425104:SSED_RS17975
uniprot id: A8FYX3
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS15390
gene id: 425104:SSED_RS15390
uniprot id: A8FXG4
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

425104:SSED RS08570
gene id: 425104:SSED_RS08570
uniprot id: A8FTU4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

425104:SSED RS14720
gene id: 425104:SSED_RS14720
uniprot id: A8FX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS17290
gene id: 425104:SSED_RS17290
uniprot id: A8FYI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

425104:SSED RS12180
gene id: 425104:SSED_RS12180
uniprot id: A8FVQ9
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS19515
gene id: 425104:SSED_RS19515
uniprot id: A8FZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

425104:SSED RS04580
gene id: 425104:SSED_RS04580
uniprot id: A8FRM7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS02280
gene id: 425104:SSED_RS02280
uniprot id: A8FQC1
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

425104:SSED RS06115
gene id: 425104:SSED_RS06115
uniprot id: A8FSI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

425104:SSED RS14130
gene id: 425104:SSED_RS14130
uniprot id: A8FWT0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

425104:SSED RS18265
gene id: 425104:SSED_RS18265
uniprot id: A8FZ23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

425104:SSED RS00170
gene id: 425104:SSED_RS00170
uniprot id: A8FP74
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

425104:SSED RS18215
gene id: 425104:SSED_RS18215
uniprot id: A8FZ13
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

425104:SSED RS00495
gene id: 425104:SSED_RS00495
uniprot id: A8FPD5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

425104:SSED RS07935
gene id: 425104:SSED_RS07935
uniprot id: A8FTH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

425104:SSED RS08130
gene id: 425104:SSED_RS08130
uniprot id: A8FTK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

425104:SSED RS13685
gene id: 425104:SSED_RS13685
uniprot id: A8FWJ1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

425104:SSED RS12225
gene id: 425104:SSED_RS12225
uniprot id: A8FVR8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

425104:SSED RS00355
gene id: 425104:SSED_RS00355
uniprot id: A8FPA7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

425104:SSED RS10165
gene id: 425104:SSED_RS10165
uniprot id: A8FUP3
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS20430
gene id: 425104:SSED_RS20430
uniprot id: A8G094
names: Similarity
messages: Belongs to the UPF0251 family.

425104:SSED RS12390
gene id: 425104:SSED_RS12390
uniprot id: A8FVV1
names: Subcellular Location Annotation
messages: Membrane

425104:SSED RS22720
gene id: 425104:SSED_RS22720
uniprot id: A8G1I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

425104:SSED RS11795
gene id: 425104:SSED_RS11795
uniprot id: A8FVI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS00380
gene id: 425104:SSED_RS00380
uniprot id: A8FPB2
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

425104:SSED RS18890
gene id: 425104:SSED_RS18890
uniprot id: A8FZE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS16670
gene id: 425104:SSED_RS16670
uniprot id: A8FY65
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

425104:SSED RS08460
gene id: 425104:SSED_RS08460
uniprot id: A8FTS2
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

425104:SSED RS18075
gene id: 425104:SSED_RS18075
uniprot id: A8FYZ3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

425104:SSED RS06385
gene id: 425104:SSED_RS06385
uniprot id: A8FSN0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

425104:SSED RS06935
gene id: 425104:SSED_RS06935
uniprot id: A8FSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

425104:SSED RS23105
gene id: 425104:SSED_RS23105
uniprot id: A8G1Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

425104:SSED RS20825
gene id: 425104:SSED_RS20825
uniprot id: A8G0H3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS08615
gene id: 425104:SSED_RS08615
uniprot id: A8FTV3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

425104:SSED RS18165
gene id: 425104:SSED_RS18165
uniprot id: A8FZ03
names: Similarity
messages: Belongs to the PhoH family.

425104:SSED RS11945
gene id: 425104:SSED_RS11945
uniprot id: A8FVL3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

425104:SSED RS05600
gene id: 425104:SSED_RS05600
uniprot id: A8FS77
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

425104:SSED RS10875
gene id: 425104:SSED_RS10875
uniprot id: A8FV23
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

425104:SSED RS15395
gene id: 425104:SSED_RS15395
uniprot id: A8FXG5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

425104:SSED RS14735
gene id: 425104:SSED_RS14735
uniprot id: A8FX53
names: Similarity
messages: Belongs to the citrate synthase family.

425104:SSED RS12295
gene id: 425104:SSED_RS12295
uniprot id: A8FVT2
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

425104:SSED RS07105
gene id: 425104:SSED_RS07105
uniprot id: A8FT10
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

425104:SSED RS12320
gene id: 425104:SSED_RS12320
uniprot id: A8FVT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

425104:SSED RS22385
gene id: 425104:SSED_RS22385
uniprot id: A8G1C4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

425104:SSED RS15685
gene id: 425104:SSED_RS15685
uniprot id: A8FXM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

425104:SSED RS07755
gene id: 425104:SSED_RS07755
uniprot id: A8FTD6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

425104:SSED RS20990
gene id: 425104:SSED_RS20990
uniprot id: A8G0K6
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

425104:SSED RS13985
gene id: 425104:SSED_RS13985
uniprot id: A8FWQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

425104:SSED RS14765
gene id: 425104:SSED_RS14765
uniprot id: A8FX59
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

425104:SSED RS11165
gene id: 425104:SSED_RS11165
uniprot id: A8FV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

425104:SSED RS17650
gene id: 425104:SSED_RS17650
uniprot id: A8FYQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

425104:SSED RS18630
gene id: 425104:SSED_RS18630
uniprot id: A8FZ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS16550
gene id: 425104:SSED_RS16550
uniprot id: A8FY41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

425104:SSED RS12055
gene id: 425104:SSED_RS12055
uniprot id: A8FVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

425104:SSED RS16115
gene id: 425104:SSED_RS16115
uniprot id: A8FXV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

425104:SSED RS16580
gene id: 425104:SSED_RS16580
uniprot id: A8FY47
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

425104:SSED RS08760
gene id: 425104:SSED_RS08760
uniprot id: A8FTY2
names: Similarity
messages: Belongs to the peptidase S49 family.

425104:SSED RS15580
gene id: 425104:SSED_RS15580
uniprot id: A8FXK1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

425104:SSED RS10565
gene id: 425104:SSED_RS10565
uniprot id: A8FUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

425104:SSED RS15015
gene id: 425104:SSED_RS15015
uniprot id: A8FXA9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

425104:SSED RS07385
gene id: 425104:SSED_RS07385
uniprot id: A8FT64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

425104:SSED RS12595
gene id: 425104:SSED_RS12595
uniprot id: A8FVZ1
names: Similarity
messages: Belongs to the agmatine deiminase family.

425104:SSED RS14685
gene id: 425104:SSED_RS14685
uniprot id: A8FX43
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

425104:SSED RS22535
gene id: 425104:SSED_RS22535
uniprot id: A8G1F4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

425104:SSED RS03845
gene id: 425104:SSED_RS03845
uniprot id: A8FR86
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

425104:SSED RS20335
gene id: 425104:SSED_RS20335
uniprot id: A8G075
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

425104:SSED RS21460
gene id: 425104:SSED_RS21460
uniprot id: A8G0V0
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

425104:SSED RS21540
gene id: 425104:SSED_RS21540
uniprot id: A8G0W5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

425104:SSED RS22540
gene id: 425104:SSED_RS22540
uniprot id: A8G1F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

425104:SSED RS11595
gene id: 425104:SSED_RS11595
uniprot id: A8FVF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

425104:SSED RS00505
gene id: 425104:SSED_RS00505
uniprot id: A8FPD7
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

425104:SSED RS05285
gene id: 425104:SSED_RS05285
uniprot id: A8FS16
names: Similarity
messages: Belongs to the peptidase M24B family.

425104:SSED RS06525
gene id: 425104:SSED_RS06525
uniprot id: A8FSQ8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

425104:SSED RS12070
gene id: 425104:SSED_RS12070
uniprot id: A8FVN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

425104:SSED RS17815
gene id: 425104:SSED_RS17815
uniprot id: A8FYT9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

425104:SSED RS06320
gene id: 425104:SSED_RS06320
uniprot id: A8FSL7
names: Similarity
messages: Belongs to the UPF0235 family.