416591:TLET RS01955
gene id: 416591:TLET_RS01955
uniprot id: A8F465
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

416591:TLET RS03000
gene id: 416591:TLET_RS03000
uniprot id: A8F4R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

416591:TLET RS02250
gene id: 416591:TLET_RS02250
uniprot id: A8F4C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

416591:TLET RS02125
gene id: 416591:TLET_RS02125
uniprot id: A8F498
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

416591:TLET RS10205
gene id: 416591:TLET_RS10205
uniprot id: A8F8Q4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

416591:TLET RS01150
gene id: 416591:TLET_RS01150
uniprot id: A8F3Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

416591:TLET RS09190
gene id: 416591:TLET_RS09190
uniprot id: A8F859
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

416591:TLET RS05575
gene id: 416591:TLET_RS05575
uniprot id: A8F670
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

416591:TLET RS05670
gene id: 416591:TLET_RS05670
uniprot id: A8F688
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS01350
gene id: 416591:TLET_RS01350
uniprot id: A8F3U8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

416591:TLET RS09690
gene id: 416591:TLET_RS09690
uniprot id: A8F8F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

416591:TLET RS06290
gene id: 416591:TLET_RS06290
uniprot id: A8F6K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS10105
gene id: 416591:TLET_RS10105
uniprot id: A8F8N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

416591:TLET RS07290
gene id: 416591:TLET_RS07290
uniprot id: A8F745
names: Similarity
messages: Belongs to the FGGY kinase family.

416591:TLET RS09590
gene id: 416591:TLET_RS09590
uniprot id: A8F8D7
names: Subcellular Location Annotation
messages: Cytoplasm

416591:TLET RS08450
gene id: 416591:TLET_RS08450
uniprot id: A8F7R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

416591:TLET RS08880
gene id: 416591:TLET_RS08880
uniprot id: A8F7Z8
names: Subcellular Location Annotation
messages: Cytoplasm

416591:TLET RS03910
gene id: 416591:TLET_RS03910
uniprot id: A8F598
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

416591:TLET RS08675
gene id: 416591:TLET_RS08675
uniprot id: A8F7V8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

416591:TLET RS05885
gene id: 416591:TLET_RS05885
uniprot id: A8F6D1
names: Similarity
messages: Belongs to the FGGY kinase family.

416591:TLET RS00735
gene id: 416591:TLET_RS00735
uniprot id: A8F3H7
names: Similarity
messages: Belongs to the alkaline phosphatase family.

416591:TLET RS10270
gene id: 416591:TLET_RS10270
uniprot id: A8F8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

416591:TLET RS08940
gene id: 416591:TLET_RS08940
uniprot id: A8F809
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

416591:TLET RS09015
gene id: 416591:TLET_RS09015
uniprot id: A8F824
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

416591:TLET RS09490
gene id: 416591:TLET_RS09490
uniprot id: A8F8B8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

416591:TLET RS06380
gene id: 416591:TLET_RS06380
uniprot id: A8F6M1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

416591:TLET RS02200
gene id: 416591:TLET_RS02200
uniprot id: A8F4B3
names: Similarity
messages: Belongs to the fabD family.

416591:TLET RS00090
gene id: 416591:TLET_RS00090
uniprot id: A8F352
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

416591:TLET RS04415
gene id: 416591:TLET_RS04415
uniprot id: A8F5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS09460
gene id: 416591:TLET_RS09460
uniprot id: A8F8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS07800
gene id: 416591:TLET_RS07800
uniprot id: A8F7E1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

416591:TLET RS03250
gene id: 416591:TLET_RS03250
uniprot id: A8F4W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

416591:TLET RS02425
gene id: 416591:TLET_RS02425
uniprot id: A8F4F6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

416591:TLET RS02545
gene id: 416591:TLET_RS02545
uniprot id: A8F4I0
names: Similarity
messages: Belongs to the MEMO1 family.

416591:TLET RS09165
gene id: 416591:TLET_RS09165
uniprot id: A8F854
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

416591:TLET RS08230
gene id: 416591:TLET_RS08230
uniprot id: A8F7M1
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS02350
gene id: 416591:TLET_RS02350
uniprot id: A8F4E3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

416591:TLET RS03990
gene id: 416591:TLET_RS03990
uniprot id: A8F5B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

416591:TLET RS08200
gene id: 416591:TLET_RS08200
uniprot id: A8F7L5
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

416591:TLET RS07315
gene id: 416591:TLET_RS07315
uniprot id: A8F750
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

416591:TLET RS04010
gene id: 416591:TLET_RS04010
uniprot id: A8F5B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

416591:TLET RS03025
gene id: 416591:TLET_RS03025
uniprot id: A8F4S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

416591:TLET RS02780
gene id: 416591:TLET_RS02780
uniprot id: A8F4M5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

416591:TLET RS04775
gene id: 416591:TLET_RS04775
uniprot id: A8F5R2
names: Similarity
messages: Belongs to the YggT family.

416591:TLET RS06865
gene id: 416591:TLET_RS06865
uniprot id: A8F6W6
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

416591:TLET RS03080
gene id: 416591:TLET_RS03080
uniprot id: A8F4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

416591:TLET RS01265
gene id: 416591:TLET_RS01265
uniprot id: A8F3T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

416591:TLET RS00675
gene id: 416591:TLET_RS00675
uniprot id: A8F3G5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

416591:TLET RS03400
gene id: 416591:TLET_RS03400
uniprot id: A8F4Z9
names: Similarity
messages: Belongs to the UPF0102 family.

416591:TLET RS00840
gene id: 416591:TLET_RS00840
uniprot id: A8F3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

416591:TLET RS06445
gene id: 416591:TLET_RS06445
uniprot id: A8F6N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

416591:TLET RS02535
gene id: 416591:TLET_RS02535
uniprot id: A8F4H8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

416591:TLET RS02655
gene id: 416591:TLET_RS02655
uniprot id: A8F4K1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS05465
gene id: 416591:TLET_RS05465
uniprot id: A8F649
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

416591:TLET RS00245
gene id: 416591:TLET_RS00245
uniprot id: A8F384
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS04160
gene id: 416591:TLET_RS04160
uniprot id: A8F5E8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

416591:TLET RS00170
gene id: 416591:TLET_RS00170
uniprot id: A8F370
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS07805
gene id: 416591:TLET_RS07805
uniprot id: A8F7E2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

416591:TLET RS07300
gene id: 416591:TLET_RS07300
uniprot id: A8F747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS08540
gene id: 416591:TLET_RS08540
uniprot id: A8F7T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

416591:TLET RS04030
gene id: 416591:TLET_RS04030
uniprot id: A8F5C2
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

416591:TLET RS02955
gene id: 416591:TLET_RS02955
uniprot id: A8F4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

416591:TLET RS00640
gene id: 416591:TLET_RS00640
uniprot id: A8F3F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

416591:TLET RS01720
gene id: 416591:TLET_RS01720
uniprot id: A8F419
names: Similarity
messages: Belongs to the UPF0473 family.

416591:TLET RS01240
gene id: 416591:TLET_RS01240
uniprot id: A8F3S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

416591:TLET RS09065
gene id: 416591:TLET_RS09065
uniprot id: A8F834
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

416591:TLET RS05000
gene id: 416591:TLET_RS05000
uniprot id: A8F5V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

416591:TLET RS05755
gene id: 416591:TLET_RS05755
uniprot id: A8F6A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

416591:TLET RS04470
gene id: 416591:TLET_RS04470
uniprot id: A8F5K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

416591:TLET RS04370
gene id: 416591:TLET_RS04370
uniprot id: A8F5I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS01935
gene id: 416591:TLET_RS01935
uniprot id: A8F461
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

416591:TLET RS09530
gene id: 416591:TLET_RS09530
uniprot id: A8F8C6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

416591:TLET RS09880
gene id: 416591:TLET_RS09880
uniprot id: A8F8J2
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

416591:TLET RS06345
gene id: 416591:TLET_RS06345
uniprot id: A8F6L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

416591:TLET RS02305
gene id: 416591:TLET_RS02305
uniprot id: A8F4D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

416591:TLET RS02905
gene id: 416591:TLET_RS02905
uniprot id: A8F4P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS00095
gene id: 416591:TLET_RS00095
uniprot id: A8F353
names: Similarity
messages: Belongs to the ClpA/ClpB family.

416591:TLET RS05150
gene id: 416591:TLET_RS05150
uniprot id: A8F5Y7
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS00670
gene id: 416591:TLET_RS00670
uniprot id: A8F3G4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

416591:TLET RS02670
gene id: 416591:TLET_RS02670
uniprot id: A8F4K4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

416591:TLET RS05905
gene id: 416591:TLET_RS05905
uniprot id: A8F6D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS02985
gene id: 416591:TLET_RS02985
uniprot id: A8F4R5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

416591:TLET RS10620
gene id: 416591:TLET_RS10620
uniprot id: A8F4I1
names: Similarity
messages: Belongs to the bacterial secretin family.

416591:TLET RS03955
gene id: 416591:TLET_RS03955
uniprot id: A8F5A7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

416591:TLET RS06870
gene id: 416591:TLET_RS06870
uniprot id: A8F6W7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

416591:TLET RS00665
gene id: 416591:TLET_RS00665
uniprot id: A8F3G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

416591:TLET RS06325
gene id: 416591:TLET_RS06325
uniprot id: A8F6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

416591:TLET RS06460
gene id: 416591:TLET_RS06460
uniprot id: A8F6N6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

416591:TLET RS01250
gene id: 416591:TLET_RS01250
uniprot id: A8F3S8
names: Similarity
messages: Belongs to the peptidase S58 family.

416591:TLET RS09350
gene id: 416591:TLET_RS09350
uniprot id: A8F890
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

416591:TLET RS07055
gene id: 416591:TLET_RS07055
uniprot id: A8F701
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

416591:TLET RS02770
gene id: 416591:TLET_RS02770
uniprot id: A8F4M3
names: Similarity
messages: Belongs to the IMPACT family.

416591:TLET RS08665
gene id: 416591:TLET_RS08665
uniprot id: A8F7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS05110
gene id: 416591:TLET_RS05110
uniprot id: A8F5X9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

416591:TLET RS04280
gene id: 416591:TLET_RS04280
uniprot id: A8F5G8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

416591:TLET RS01645
gene id: 416591:TLET_RS01645
uniprot id: A8F404
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS01100
gene id: 416591:TLET_RS01100
uniprot id: A8F3P9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

416591:TLET RS02625
gene id: 416591:TLET_RS02625
uniprot id: A8F4J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

416591:TLET RS07755
gene id: 416591:TLET_RS07755
uniprot id: A8F7D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

416591:TLET RS00265
gene id: 416591:TLET_RS00265
uniprot id: A8F388
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS00730
gene id: 416591:TLET_RS00730
uniprot id: A8F3H6
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

416591:TLET RS07155
gene id: 416591:TLET_RS07155
uniprot id: A8F721
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

416591:TLET RS00685
gene id: 416591:TLET_RS00685
uniprot id: A8F3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS09060
gene id: 416591:TLET_RS09060
uniprot id: A8F833
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

416591:TLET RS05230
gene id: 416591:TLET_RS05230
uniprot id: A8F603
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS09020
gene id: 416591:TLET_RS09020
uniprot id: A8F825
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

416591:TLET RS10015
gene id: 416591:TLET_RS10015
uniprot id: A8F8L6
names: Subcellular Location Annotation
messages: Cytoplasm

416591:TLET RS08885
gene id: 416591:TLET_RS08885
uniprot id: A8F7Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

416591:TLET RS10370
gene id: 416591:TLET_RS10370
uniprot id: A8F8T8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

416591:TLET RS05310
gene id: 416591:TLET_RS05310
uniprot id: A8F619
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

416591:TLET RS00850
gene id: 416591:TLET_RS00850
uniprot id: A8F3K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

416591:TLET RS10625
gene id: 416591:TLET_RS10625
uniprot id: A8F4K7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

416591:TLET RS06820
gene id: 416591:TLET_RS06820
uniprot id: A8F6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

416591:TLET RS00610
gene id: 416591:TLET_RS00610
uniprot id: A8F3F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS10405
gene id: 416591:TLET_RS10405
uniprot id: A8F8U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS03030
gene id: 416591:TLET_RS03030
uniprot id: A8F4S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

416591:TLET RS05065
gene id: 416591:TLET_RS05065
uniprot id: A8F5X0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

416591:TLET RS09370
gene id: 416591:TLET_RS09370
uniprot id: A8F894
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

416591:TLET RS05620
gene id: 416591:TLET_RS05620
uniprot id: A8F679
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

416591:TLET RS02420
gene id: 416591:TLET_RS02420
uniprot id: A8F4F5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

416591:TLET RS03935
gene id: 416591:TLET_RS03935
uniprot id: A8F5A3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS07080
gene id: 416591:TLET_RS07080
uniprot id: A8F706
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

416591:TLET RS09485
gene id: 416591:TLET_RS09485
uniprot id: A8F8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

416591:TLET RS09620
gene id: 416591:TLET_RS09620
uniprot id: A8F8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

416591:TLET RS04025
gene id: 416591:TLET_RS04025
uniprot id: A8F5C1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

416591:TLET RS02370
gene id: 416591:TLET_RS02370
uniprot id: A8F4E7
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

416591:TLET RS03090
gene id: 416591:TLET_RS03090
uniprot id: A8F4T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

416591:TLET RS02965
gene id: 416591:TLET_RS02965
uniprot id: A8F4R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

416591:TLET RS10455
gene id: 416591:TLET_RS10455
uniprot id: A8F8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS09860
gene id: 416591:TLET_RS09860
uniprot id: A8F8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

416591:TLET RS07780
gene id: 416591:TLET_RS07780
uniprot id: A8F7D7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

416591:TLET RS08685
gene id: 416591:TLET_RS08685
uniprot id: A8F7W0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

416591:TLET RS02300
gene id: 416591:TLET_RS02300
uniprot id: A8F4D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

416591:TLET RS04545
gene id: 416591:TLET_RS04545
uniprot id: A8F5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

416591:TLET RS07365
gene id: 416591:TLET_RS07365
uniprot id: A8F759
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

416591:TLET RS08810
gene id: 416591:TLET_RS08810
uniprot id: A8F7Y5
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

416591:TLET RS08470
gene id: 416591:TLET_RS08470
uniprot id: A8F7R8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

416591:TLET RS03050
gene id: 416591:TLET_RS03050
uniprot id: A8F4S8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

416591:TLET RS09815
gene id: 416591:TLET_RS09815
uniprot id: A8F8H9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

416591:TLET RS05330
gene id: 416591:TLET_RS05330
uniprot id: A8F622
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

416591:TLET RS07285
gene id: 416591:TLET_RS07285
uniprot id: A8F744
names: Similarity
messages: Belongs to the peptidase M29 family.

416591:TLET RS01885
gene id: 416591:TLET_RS01885
uniprot id: A8F451
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

416591:TLET RS09100
gene id: 416591:TLET_RS09100
uniprot id: A8F841
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

416591:TLET RS07645
gene id: 416591:TLET_RS07645
uniprot id: A8F7B0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

416591:TLET RS01570
gene id: 416591:TLET_RS01570
uniprot id: A8F3Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

416591:TLET RS08280
gene id: 416591:TLET_RS08280
uniprot id: A8F7N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

416591:TLET RS00020
gene id: 416591:TLET_RS00020
uniprot id: A8F347
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

416591:TLET RS07660
gene id: 416591:TLET_RS07660
uniprot id: A8F7B3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

416591:TLET RS06610
gene id: 416591:TLET_RS06610
uniprot id: A8F6R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS04435
gene id: 416591:TLET_RS04435
uniprot id: A8F5J9
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS01355
gene id: 416591:TLET_RS01355
uniprot id: A8F3U9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

416591:TLET RS04845
gene id: 416591:TLET_RS04845
uniprot id: A8F5S6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

416591:TLET RS05195
gene id: 416591:TLET_RS05195
uniprot id: A8F5Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

416591:TLET RS03560
gene id: 416591:TLET_RS03560
uniprot id: A8F531
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

416591:TLET RS02730
gene id: 416591:TLET_RS02730
uniprot id: A8F4L5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS10170
gene id: 416591:TLET_RS10170
uniprot id: A8F8P7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

416591:TLET RS01325
gene id: 416591:TLET_RS01325
uniprot id: A8F3U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

416591:TLET RS09625
gene id: 416591:TLET_RS09625
uniprot id: A8F8E4
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

416591:TLET RS01110
gene id: 416591:TLET_RS01110
uniprot id: A8F3Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS00380
gene id: 416591:TLET_RS00380
uniprot id: A8F3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS08415
gene id: 416591:TLET_RS08415
uniprot id: A8F7Q8
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

416591:TLET RS03915
gene id: 416591:TLET_RS03915
uniprot id: A8F599
names: Similarity
messages: Belongs to the Fur family.

416591:TLET RS01870
gene id: 416591:TLET_RS01870
uniprot id: A8F448
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

416591:TLET RS03200
gene id: 416591:TLET_RS03200
uniprot id: A8F4V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

416591:TLET RS10495
gene id: 416591:TLET_RS10495
uniprot id: A8F8W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

416591:TLET RS03060
gene id: 416591:TLET_RS03060
uniprot id: A8F4T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

416591:TLET RS10535
gene id: 416591:TLET_RS10535
uniprot id: A8F8X1
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS03315
gene id: 416591:TLET_RS03315
uniprot id: A8F4Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS07695
gene id: 416591:TLET_RS07695
uniprot id: A8F7C0
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

416591:TLET RS03655
gene id: 416591:TLET_RS03655
uniprot id: A8F550
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

416591:TLET RS00225
gene id: 416591:TLET_RS00225
uniprot id: A8F380
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

416591:TLET RS06615
gene id: 416591:TLET_RS06615
uniprot id: A8F6R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS10165
gene id: 416591:TLET_RS10165
uniprot id: A8F8P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

416591:TLET RS09000
gene id: 416591:TLET_RS09000
uniprot id: A8F821
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

416591:TLET RS02030
gene id: 416591:TLET_RS02030
uniprot id: A8F479
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

416591:TLET RS07380
gene id: 416591:TLET_RS07380
uniprot id: A8F762
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS02445
gene id: 416591:TLET_RS02445
uniprot id: A8F4G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

416591:TLET RS07230
gene id: 416591:TLET_RS07230
uniprot id: A8F733
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

416591:TLET RS05515
gene id: 416591:TLET_RS05515
uniprot id: A8F659
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

416591:TLET RS01850
gene id: 416591:TLET_RS01850
uniprot id: A8F445
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

416591:TLET RS09380
gene id: 416591:TLET_RS09380
uniprot id: A8F896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

416591:TLET RS01640
gene id: 416591:TLET_RS01640
uniprot id: A8F403
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

416591:TLET RS07065
gene id: 416591:TLET_RS07065
uniprot id: A8F703
names: Similarity
messages: Belongs to the RibF family.

416591:TLET RS07240
gene id: 416591:TLET_RS07240
uniprot id: A8F735
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

416591:TLET RS02725
gene id: 416591:TLET_RS02725
uniprot id: A8F4L4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

416591:TLET RS01115
gene id: 416591:TLET_RS01115
uniprot id: A8F3Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS08805
gene id: 416591:TLET_RS08805
uniprot id: A8F7Y4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

416591:TLET RS00280
gene id: 416591:TLET_RS00280
uniprot id: A8F391
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS02885
gene id: 416591:TLET_RS02885
uniprot id: A8F4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

416591:TLET RS09160
gene id: 416591:TLET_RS09160
uniprot id: A8F853
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS09845
gene id: 416591:TLET_RS09845
uniprot id: A8F8I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

416591:TLET RS01490
gene id: 416591:TLET_RS01490
uniprot id: A8F3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

416591:TLET RS05985
gene id: 416591:TLET_RS05985
uniprot id: A8F6F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

416591:TLET RS02675
gene id: 416591:TLET_RS02675
uniprot id: A8F4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

416591:TLET RS07275
gene id: 416591:TLET_RS07275
uniprot id: A8F742
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS08465
gene id: 416591:TLET_RS08465
uniprot id: A8F7R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS10345
gene id: 416591:TLET_RS10345
uniprot id: A8F8T3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

416591:TLET RS02075
gene id: 416591:TLET_RS02075
uniprot id: A8F488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS03265
gene id: 416591:TLET_RS03265
uniprot id: A8F4X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

416591:TLET RS09225
gene id: 416591:TLET_RS09225
uniprot id: A8F866
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

416591:TLET RS00025
gene id: 416591:TLET_RS00025
uniprot id: A8F344
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS00765
gene id: 416591:TLET_RS00765
uniprot id: A8F3I3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

416591:TLET RS05180
gene id: 416591:TLET_RS05180
uniprot id: A8F5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

416591:TLET RS10010
gene id: 416591:TLET_RS10010
uniprot id: A8F8L5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

416591:TLET RS09180
gene id: 416591:TLET_RS09180
uniprot id: A8F857
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

416591:TLET RS04250
gene id: 416591:TLET_RS04250
uniprot id: A8F5G2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

416591:TLET RS02235
gene id: 416591:TLET_RS02235
uniprot id: A8F4C0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

416591:TLET RS05570
gene id: 416591:TLET_RS05570
uniprot id: A8F669
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

416591:TLET RS03240
gene id: 416591:TLET_RS03240
uniprot id: A8F4W7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

416591:TLET RS00720
gene id: 416591:TLET_RS00720
uniprot id: A8F3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

416591:TLET RS07735
gene id: 416591:TLET_RS07735
uniprot id: A8F7C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS05220
gene id: 416591:TLET_RS05220
uniprot id: A8F601
names: Similarity
messages: Belongs to the BMP lipoprotein family.

416591:TLET RS03085
gene id: 416591:TLET_RS03085
uniprot id: A8F4T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

416591:TLET RS09095
gene id: 416591:TLET_RS09095
uniprot id: A8F840
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

416591:TLET RS00585
gene id: 416591:TLET_RS00585
uniprot id: A8F3E7
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

416591:TLET RS09835
gene id: 416591:TLET_RS09835
uniprot id: A8F8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

416591:TLET RS05820
gene id: 416591:TLET_RS05820
uniprot id: A8F6B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

416591:TLET RS02460
gene id: 416591:TLET_RS02460
uniprot id: A8F4G3
names: Similarity
messages: Belongs to the peptidase U62 family.

416591:TLET RS01530
gene id: 416591:TLET_RS01530
uniprot id: A8F3Y3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

416591:TLET RS03705
gene id: 416591:TLET_RS03705
uniprot id: A8F560
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

416591:TLET RS10520
gene id: 416591:TLET_RS10520
uniprot id: A8F8W8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

416591:TLET RS06805
gene id: 416591:TLET_RS06805
uniprot id: A8F6V4
names: Similarity
messages: Belongs to the FGGY kinase family.

416591:TLET RS00885
gene id: 416591:TLET_RS00885
uniprot id: A8F3K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

416591:TLET RS07690
gene id: 416591:TLET_RS07690
uniprot id: A8F7B9
names: Cofactor
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

416591:TLET RS09725
gene id: 416591:TLET_RS09725
uniprot id: A8F8G1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

416591:TLET RS03395
gene id: 416591:TLET_RS03395
uniprot id: A8F4Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

416591:TLET RS02360
gene id: 416591:TLET_RS02360
uniprot id: A8F4E5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

416591:TLET RS07585
gene id: 416591:TLET_RS07585
uniprot id: A8F7A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

416591:TLET RS10375
gene id: 416591:TLET_RS10375
uniprot id: A8F8T9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

416591:TLET RS03365
gene id: 416591:TLET_RS03365
uniprot id: A8F4Z2
names: Similarity
messages: Belongs to the sigma-54 factor family.

416591:TLET RS03635
gene id: 416591:TLET_RS03635
uniprot id: A8F546
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS06575
gene id: 416591:TLET_RS06575
uniprot id: A8F6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

416591:TLET RS04325
gene id: 416591:TLET_RS04325
uniprot id: A8F5H7
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS06650
gene id: 416591:TLET_RS06650
uniprot id: A8F6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS08235
gene id: 416591:TLET_RS08235
uniprot id: A8F7M2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

416591:TLET RS08480
gene id: 416591:TLET_RS08480
uniprot id: A8F7S0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

416591:TLET RS05540
gene id: 416591:TLET_RS05540
uniprot id: A8F664
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

416591:TLET RS02995
gene id: 416591:TLET_RS02995
uniprot id: A8F4R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

416591:TLET RS03255
gene id: 416591:TLET_RS03255
uniprot id: A8F4X0
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS04640
gene id: 416591:TLET_RS04640
uniprot id: A8F5P0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

416591:TLET RS06440
gene id: 416591:TLET_RS06440
uniprot id: A8F6N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

416591:TLET RS05445
gene id: 416591:TLET_RS05445
uniprot id: A8F645
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

416591:TLET RS04890
gene id: 416591:TLET_RS04890
uniprot id: A8F5T5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

416591:TLET RS02580
gene id: 416591:TLET_RS02580
uniprot id: A8F4I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

416591:TLET RS08000
gene id: 416591:TLET_RS08000
uniprot id: A8F7H8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

416591:TLET RS02960
gene id: 416591:TLET_RS02960
uniprot id: A8F4R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

416591:TLET RS00920
gene id: 416591:TLET_RS00920
uniprot id: A8F3L4
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

416591:TLET RS07530
gene id: 416591:TLET_RS07530
uniprot id: A8F791
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

416591:TLET RS00375
gene id: 416591:TLET_RS00375
uniprot id: A8F3B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS07855
gene id: 416591:TLET_RS07855
uniprot id: A8F7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS03320
gene id: 416591:TLET_RS03320
uniprot id: A8F4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

416591:TLET RS08490
gene id: 416591:TLET_RS08490
uniprot id: A8F7S2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

416591:TLET RS03245
gene id: 416591:TLET_RS03245
uniprot id: A8F4W8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

416591:TLET RS08180
gene id: 416591:TLET_RS08180
uniprot id: A8F7L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

416591:TLET RS05395
gene id: 416591:TLET_RS05395
uniprot id: A8F635
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Interacts with FtsZ.

416591:TLET RS01070
gene id: 416591:TLET_RS01070
uniprot id: A8F3P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

416591:TLET RS09980
gene id: 416591:TLET_RS09980
uniprot id: A8F8K9
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS03890
gene id: 416591:TLET_RS03890
uniprot id: A8F594
names: Similarity
messages: Belongs to the FBPase class 2 family.

416591:TLET RS08520
gene id: 416591:TLET_RS08520
uniprot id: A8F7S8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

416591:TLET RS05845
gene id: 416591:TLET_RS05845
uniprot id: A8F6C3
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

416591:TLET RS08475
gene id: 416591:TLET_RS08475
uniprot id: A8F7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

416591:TLET RS01010
gene id: 416591:TLET_RS01010
uniprot id: A8F3N2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

416591:TLET RS01920
gene id: 416591:TLET_RS01920
uniprot id: A8F458
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

416591:TLET RS00825
gene id: 416591:TLET_RS00825
uniprot id: A8F3J5
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS01455
gene id: 416591:TLET_RS01455
uniprot id: A8F3W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

416591:TLET RS07565
gene id: 416591:TLET_RS07565
uniprot id: A8F798
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

416591:TLET RS06660
gene id: 416591:TLET_RS06660
uniprot id: A8F6S5
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

416591:TLET RS08970
gene id: 416591:TLET_RS08970
uniprot id: A8F815
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

416591:TLET RS02945
gene id: 416591:TLET_RS02945
uniprot id: A8F4Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

416591:TLET RS07885
gene id: 416591:TLET_RS07885
uniprot id: A8F7F8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

416591:TLET RS08995
gene id: 416591:TLET_RS08995
uniprot id: A8F820
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS07760
gene id: 416591:TLET_RS07760
uniprot id: A8F7D3
names: Similarity
messages: Belongs to the asp23 family.

416591:TLET RS02315
gene id: 416591:TLET_RS02315
uniprot id: A8F4D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

416591:TLET RS08775
gene id: 416591:TLET_RS08775
uniprot id: A8F7X8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

416591:TLET RS06685
gene id: 416591:TLET_RS06685
uniprot id: A8F6T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS05735
gene id: 416591:TLET_RS05735
uniprot id: A8F6A1
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS06670
gene id: 416591:TLET_RS06670
uniprot id: A8F6S7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

416591:TLET RS00045
gene id: 416591:TLET_RS00045
uniprot id: A8F8Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

416591:TLET RS03535
gene id: 416591:TLET_RS03535
uniprot id: A8F526
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

416591:TLET RS06475
gene id: 416591:TLET_RS06475
uniprot id: A8F6N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

416591:TLET RS04315
gene id: 416591:TLET_RS04315
uniprot id: A8F5H5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

416591:TLET RS01890
gene id: 416591:TLET_RS01890
uniprot id: A8F452
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

416591:TLET RS04720
gene id: 416591:TLET_RS04720
uniprot id: A8F5Q2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

416591:TLET RS10065
gene id: 416591:TLET_RS10065
uniprot id: A8F8M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

416591:TLET RS02540
gene id: 416591:TLET_RS02540
uniprot id: A8F4H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

416591:TLET RS05235
gene id: 416591:TLET_RS05235
uniprot id: A8F604
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS03445
gene id: 416591:TLET_RS03445
uniprot id: A8F508
names: Similarity
messages: Belongs to the BMP lipoprotein family.

416591:TLET RS03130
gene id: 416591:TLET_RS03130
uniprot id: A8F4U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

416591:TLET RS01680
gene id: 416591:TLET_RS01680
uniprot id: A8F411
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

416591:TLET RS01900
gene id: 416591:TLET_RS01900
uniprot id: A8F454
names: Similarity
messages: Belongs to the RecJ family.

416591:TLET RS02430
gene id: 416591:TLET_RS02430
uniprot id: A8F4F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

416591:TLET RS05490
gene id: 416591:TLET_RS05490
uniprot id: A8F654
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS00810
gene id: 416591:TLET_RS00810
uniprot id: A8F3J2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

416591:TLET RS01740
gene id: 416591:TLET_RS01740
uniprot id: A8F423
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS10025
gene id: 416591:TLET_RS10025
uniprot id: A8F8L8
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

416591:TLET RS02980
gene id: 416591:TLET_RS02980
uniprot id: A8F4R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

416591:TLET RS01255
gene id: 416591:TLET_RS01255
uniprot id: A8F3S9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

416591:TLET RS07400
gene id: 416591:TLET_RS07400
uniprot id: A8F766
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

416591:TLET RS00130
gene id: 416591:TLET_RS00130
uniprot id: A8F362
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS02180
gene id: 416591:TLET_RS02180
uniprot id: A8F4A9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

416591:TLET RS10200
gene id: 416591:TLET_RS10200
uniprot id: A8F8Q3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

416591:TLET RS03610
gene id: 416591:TLET_RS03610
uniprot id: A8F541
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

416591:TLET RS08285
gene id: 416591:TLET_RS08285
uniprot id: A8F7N2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

416591:TLET RS02620
gene id: 416591:TLET_RS02620
uniprot id: A8F4J5
names: Similarity
messages: Belongs to the peptidase S41A family.

416591:TLET RS03040
gene id: 416591:TLET_RS03040
uniprot id: A8F4S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

416591:TLET RS01575
gene id: 416591:TLET_RS01575
uniprot id: A8F3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

416591:TLET RS00705
gene id: 416591:TLET_RS00705
uniprot id: A8F3H1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

416591:TLET RS03945
gene id: 416591:TLET_RS03945
uniprot id: A8F5A5
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS02140
gene id: 416591:TLET_RS02140
uniprot id: A8F4A1
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS02185
gene id: 416591:TLET_RS02185
uniprot id: A8F4B0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

416591:TLET RS02805
gene id: 416591:TLET_RS02805
uniprot id: A8F4N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

416591:TLET RS00360
gene id: 416591:TLET_RS00360
uniprot id: A8F3A7
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS06525
gene id: 416591:TLET_RS06525
uniprot id: A8F6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

416591:TLET RS06185
gene id: 416591:TLET_RS06185
uniprot id: A8F6I5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

416591:TLET RS02490
gene id: 416591:TLET_RS02490
uniprot id: A8F4G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

416591:TLET RS01030
gene id: 416591:TLET_RS01030
uniprot id: A8F3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS08770
gene id: 416591:TLET_RS08770
uniprot id: A8F7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS05935
gene id: 416591:TLET_RS05935
uniprot id: A8F6E0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

416591:TLET RS03660
gene id: 416591:TLET_RS03660
uniprot id: A8F551
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

416591:TLET RS05155
gene id: 416591:TLET_RS05155
uniprot id: A8F5Y8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

416591:TLET RS09480
gene id: 416591:TLET_RS09480
uniprot id: A8F8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

416591:TLET RS02520
gene id: 416591:TLET_RS02520
uniprot id: A8F4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

416591:TLET RS07900
gene id: 416591:TLET_RS07900
uniprot id: A8F7G0
names: Similarity
messages: Belongs to the peptidase U62 family.

416591:TLET RS03545
gene id: 416591:TLET_RS03545
uniprot id: A8F528
names: Similarity
messages: Belongs to the TlyA family.

416591:TLET RS03500
gene id: 416591:TLET_RS03500
uniprot id: A8F519
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

416591:TLET RS01505
gene id: 416591:TLET_RS01505
uniprot id: A8F3X8
names: Similarity
messages: Belongs to the DprA/Smf family.

416591:TLET RS02415
gene id: 416591:TLET_RS02415
uniprot id: A8F4F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

416591:TLET RS03175
gene id: 416591:TLET_RS03175
uniprot id: A8F4V4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

416591:TLET RS08050
gene id: 416591:TLET_RS08050
uniprot id: A8F7I7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

416591:TLET RS04240
gene id: 416591:TLET_RS04240
uniprot id: A8F5G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

416591:TLET RS01945
gene id: 416591:TLET_RS01945
uniprot id: A8F463
names: Function
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

416591:TLET RS01190
gene id: 416591:TLET_RS01190
uniprot id: A8F3R6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

416591:TLET RS09360
gene id: 416591:TLET_RS09360
uniprot id: A8F892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

416591:TLET RS03520
gene id: 416591:TLET_RS03520
uniprot id: A8F523
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

416591:TLET RS09400
gene id: 416591:TLET_RS09400
uniprot id: A8F8A0
names: Similarity
messages: Belongs to the serpin family.

416591:TLET RS06985
gene id: 416591:TLET_RS06985
uniprot id: A8F6Y7
names: Similarity
messages: Belongs to the aspartokinase family.

416591:TLET RS04055
gene id: 416591:TLET_RS04055
uniprot id: A8F5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

416591:TLET RS07280
gene id: 416591:TLET_RS07280
uniprot id: A8F743
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS07110
gene id: 416591:TLET_RS07110
uniprot id: A8F712
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

416591:TLET RS02375
gene id: 416591:TLET_RS02375
uniprot id: A8F4E8
names: Similarity
messages: Belongs to the acylphosphatase family.

416591:TLET RS03370
gene id: 416591:TLET_RS03370
uniprot id: A8F4Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

416591:TLET RS05015
gene id: 416591:TLET_RS05015
uniprot id: A8F5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

416591:TLET RS01785
gene id: 416591:TLET_RS01785
uniprot id: A8F432
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS00845
gene id: 416591:TLET_RS00845
uniprot id: A8F3J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

416591:TLET RS04170
gene id: 416591:TLET_RS04170
uniprot id: A8F5F0
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS04810
gene id: 416591:TLET_RS04810
uniprot id: A8F5R9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

416591:TLET RS01630
gene id: 416591:TLET_RS01630
uniprot id: A8F401
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

416591:TLET RS09465
gene id: 416591:TLET_RS09465
uniprot id: A8F8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS01365
gene id: 416591:TLET_RS01365
uniprot id: A8F3V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

416591:TLET RS08250
gene id: 416591:TLET_RS08250
uniprot id: A8F7M5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

416591:TLET RS08840
gene id: 416591:TLET_RS08840
uniprot id: A8F7Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

416591:TLET RS01005
gene id: 416591:TLET_RS01005
uniprot id: A8F3N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

416591:TLET RS03270
gene id: 416591:TLET_RS03270
uniprot id: A8F4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS02870
gene id: 416591:TLET_RS02870
uniprot id: A8F4P2
names: Similarity
messages: Belongs to the UPF0111 family.

416591:TLET RS06260
gene id: 416591:TLET_RS06260
uniprot id: A8F6J9
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS02440
gene id: 416591:TLET_RS02440
uniprot id: A8F4F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

416591:TLET RS10400
gene id: 416591:TLET_RS10400
uniprot id: A8F8U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS09080
gene id: 416591:TLET_RS09080
uniprot id: A8F837
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

416591:TLET RS04880
gene id: 416591:TLET_RS04880
uniprot id: A8F5T3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

416591:TLET RS02340
gene id: 416591:TLET_RS02340
uniprot id: A8F4E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

416591:TLET RS04290
gene id: 416591:TLET_RS04290
uniprot id: A8F5H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS06330
gene id: 416591:TLET_RS06330
uniprot id: A8F6L2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

416591:TLET RS01510
gene id: 416591:TLET_RS01510
uniprot id: A8F3X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

416591:TLET RS03180
gene id: 416591:TLET_RS03180
uniprot id: A8F4V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

416591:TLET RS05345
gene id: 416591:TLET_RS05345
uniprot id: A8F625
names: Similarity
messages: Belongs to the BMP lipoprotein family.

416591:TLET RS06740
gene id: 416591:TLET_RS06740
uniprot id: A8F6U1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

416591:TLET RS08740
gene id: 416591:TLET_RS08740
uniprot id: A8F7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS03335
gene id: 416591:TLET_RS03335
uniprot id: A8F4Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

416591:TLET RS03275
gene id: 416591:TLET_RS03275
uniprot id: A8F4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS04130
gene id: 416591:TLET_RS04130
uniprot id: A8F5E2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

416591:TLET RS04960
gene id: 416591:TLET_RS04960
uniprot id: A8F5U9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

416591:TLET RS09265
gene id: 416591:TLET_RS09265
uniprot id: A8F874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS00180
gene id: 416591:TLET_RS00180
uniprot id: A8F372
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS08605
gene id: 416591:TLET_RS08605
uniprot id: A8F7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS00260
gene id: 416591:TLET_RS00260
uniprot id: A8F387
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

416591:TLET RS03470
gene id: 416591:TLET_RS03470
uniprot id: A8F513
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

416591:TLET RS09540
gene id: 416591:TLET_RS09540
uniprot id: A8F8C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

416591:TLET RS04400
gene id: 416591:TLET_RS04400
uniprot id: A8F5J2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

416591:TLET RS05520
gene id: 416591:TLET_RS05520
uniprot id: A8F660
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

416591:TLET RS07005
gene id: 416591:TLET_RS07005
uniprot id: A8F6Z1
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS09375
gene id: 416591:TLET_RS09375
uniprot id: A8F895
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

416591:TLET RS01915
gene id: 416591:TLET_RS01915
uniprot id: A8F457
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

416591:TLET RS02190
gene id: 416591:TLET_RS02190
uniprot id: A8F4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

416591:TLET RS07010
gene id: 416591:TLET_RS07010
uniprot id: A8F6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

416591:TLET RS09870
gene id: 416591:TLET_RS09870
uniprot id: A8F8J0
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS07545
gene id: 416591:TLET_RS07545
uniprot id: A8F794
names: Similarity
messages: Belongs to the Skp family.

416591:TLET RS09765
gene id: 416591:TLET_RS09765
uniprot id: A8F8G9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

416591:TLET RS06880
gene id: 416591:TLET_RS06880
uniprot id: A8F6W9
names: Similarity
messages: Belongs to the AOR/FOR family.

416591:TLET RS00635
gene id: 416591:TLET_RS00635
uniprot id: A8F3F7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

416591:TLET RS08635
gene id: 416591:TLET_RS08635
uniprot id: A8F7V0
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

416591:TLET RS07685
gene id: 416591:TLET_RS07685
uniprot id: A8F7B8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

416591:TLET RS02970
gene id: 416591:TLET_RS02970
uniprot id: A8F4R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

416591:TLET RS01775
gene id: 416591:TLET_RS01775
uniprot id: A8F430
names: Similarity
messages: Belongs to the archease family.

416591:TLET RS10525
gene id: 416591:TLET_RS10525
uniprot id: A8F8W9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

416591:TLET RS01950
gene id: 416591:TLET_RS01950
uniprot id: A8F464
names: Similarity
messages: Belongs to the GSP E family.

416591:TLET RS07130
gene id: 416591:TLET_RS07130
uniprot id: A8F716
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

416591:TLET RS05740
gene id: 416591:TLET_RS05740
uniprot id: A8F6A2
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS08725
gene id: 416591:TLET_RS08725
uniprot id: A8F7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

416591:TLET RS10350
gene id: 416591:TLET_RS10350
uniprot id: A8F8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

416591:TLET RS00565
gene id: 416591:TLET_RS00565
uniprot id: A8F3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS10255
gene id: 416591:TLET_RS10255
uniprot id: A8F8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

416591:TLET RS00410
gene id: 416591:TLET_RS00410
uniprot id: A8F3B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

416591:TLET RS00660
gene id: 416591:TLET_RS00660
uniprot id: A8F3G2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

416591:TLET RS06400
gene id: 416591:TLET_RS06400
uniprot id: A8F6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

416591:TLET RS07610
gene id: 416591:TLET_RS07610
uniprot id: A8F7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

416591:TLET RS01755
gene id: 416591:TLET_RS01755
uniprot id: A8F426
names: Similarity
messages: Belongs to the histone deacetylase family.

416591:TLET RS05875
gene id: 416591:TLET_RS05875
uniprot id: A8F6C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

416591:TLET RS10315
gene id: 416591:TLET_RS10315
uniprot id: A8F8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS09260
gene id: 416591:TLET_RS09260
uniprot id: A8F873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS10210
gene id: 416591:TLET_RS10210
uniprot id: A8F8Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

416591:TLET RS03485
gene id: 416591:TLET_RS03485
uniprot id: A8F516
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

416591:TLET RS07085
gene id: 416591:TLET_RS07085
uniprot id: A8F707
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

416591:TLET RS03965
gene id: 416591:TLET_RS03965
uniprot id: A8F5A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS06250
gene id: 416591:TLET_RS06250
uniprot id: A8F6J6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

416591:TLET RS03005
gene id: 416591:TLET_RS03005
uniprot id: A8F4R9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

416591:TLET RS09670
gene id: 416591:TLET_RS09670
uniprot id: A8F8F3
names: Similarity
messages: Belongs to the bacterial secretin family.

416591:TLET RS01335
gene id: 416591:TLET_RS01335
uniprot id: A8F3U5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS07090
gene id: 416591:TLET_RS07090
uniprot id: A8F708
names: Subcellular Location Annotation
messages: Cytoplasm

416591:TLET RS02975
gene id: 416591:TLET_RS02975
uniprot id: A8F4R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

416591:TLET RS10090
gene id: 416591:TLET_RS10090
uniprot id: A8F8N1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS07100
gene id: 416591:TLET_RS07100
uniprot id: A8F710
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

416591:TLET RS01430
gene id: 416591:TLET_RS01430
uniprot id: A8F3W3
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS03350
gene id: 416591:TLET_RS03350
uniprot id: A8F4Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

416591:TLET RS06920
gene id: 416591:TLET_RS06920
uniprot id: A8F6X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS02500
gene id: 416591:TLET_RS02500
uniprot id: A8F4H1
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

416591:TLET RS06900
gene id: 416591:TLET_RS06900
uniprot id: A8F6X1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

416591:TLET RS01925
gene id: 416591:TLET_RS01925
uniprot id: A8F459
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

416591:TLET RS09150
gene id: 416591:TLET_RS09150
uniprot id: A8F851
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

416591:TLET RS01235
gene id: 416591:TLET_RS01235
uniprot id: A8F3S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

416591:TLET RS02470
gene id: 416591:TLET_RS02470
uniprot id: A8F4G5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

416591:TLET RS02830
gene id: 416591:TLET_RS02830
uniprot id: A8F4N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

416591:TLET RS08835
gene id: 416591:TLET_RS08835
uniprot id: A8F7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS07295
gene id: 416591:TLET_RS07295
uniprot id: A8F746
names: Similarity
messages: Belongs to the BtpA family.

416591:TLET RS00015
gene id: 416591:TLET_RS00015
uniprot id: A8F346
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

416591:TLET RS10080
gene id: 416591:TLET_RS10080
uniprot id: A8F8M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

416591:TLET RS01605
gene id: 416591:TLET_RS01605
uniprot id: A8F3Z6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

416591:TLET RS06710
gene id: 416591:TLET_RS06710
uniprot id: A8F6T5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

416591:TLET RS09215
gene id: 416591:TLET_RS09215
uniprot id: A8F864
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

416591:TLET RS03510
gene id: 416591:TLET_RS03510
uniprot id: A8F521
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

416591:TLET RS06275
gene id: 416591:TLET_RS06275
uniprot id: A8F6K2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

416591:TLET RS01800
gene id: 416591:TLET_RS01800
uniprot id: A8F435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS05650
gene id: 416591:TLET_RS05650
uniprot id: A8F685
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

416591:TLET RS02680
gene id: 416591:TLET_RS02680
uniprot id: A8F4K6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

416591:TLET RS05360
gene id: 416591:TLET_RS05360
uniprot id: A8F628
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS03390
gene id: 416591:TLET_RS03390
uniprot id: A8F4Z7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

416591:TLET RS04970
gene id: 416591:TLET_RS04970
uniprot id: A8F5V1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

416591:TLET RS07895
gene id: 416591:TLET_RS07895
uniprot id: A8F7F9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS09735
gene id: 416591:TLET_RS09735
uniprot id: A8F8G3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS00655
gene id: 416591:TLET_RS00655
uniprot id: A8F3G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

416591:TLET RS07990
gene id: 416591:TLET_RS07990
uniprot id: A8F7H6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

416591:TLET RS04215
gene id: 416591:TLET_RS04215
uniprot id: A8F5F7
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

416591:TLET RS01225
gene id: 416591:TLET_RS01225
uniprot id: A8F3S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

416591:TLET RS09745
gene id: 416591:TLET_RS09745
uniprot id: A8F8G5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

416591:TLET RS04710
gene id: 416591:TLET_RS04710
uniprot id: A8F5Q0
names: Similarity
messages: Belongs to the class-I fumarase family.

416591:TLET RS02390
gene id: 416591:TLET_RS02390
uniprot id: A8F4F1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

416591:TLET RS02345
gene id: 416591:TLET_RS02345
uniprot id: A8F4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

416591:TLET RS04245
gene id: 416591:TLET_RS04245
uniprot id: A8F5G1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS03055
gene id: 416591:TLET_RS03055
uniprot id: A8F4S9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

416591:TLET RS03845
gene id: 416591:TLET_RS03845
uniprot id: A8F585
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

416591:TLET RS02895
gene id: 416591:TLET_RS02895
uniprot id: A8F4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

416591:TLET RS07135
gene id: 416591:TLET_RS07135
uniprot id: A8F717
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

416591:TLET RS05430
gene id: 416591:TLET_RS05430
uniprot id: A8F642
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

416591:TLET RS03190
gene id: 416591:TLET_RS03190
uniprot id: A8F4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

416591:TLET RS07675
gene id: 416591:TLET_RS07675
uniprot id: A8F7B6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

416591:TLET RS06470
gene id: 416591:TLET_RS06470
uniprot id: A8F6N8
names: Similarity
messages: Belongs to the UPF0145 family.

416591:TLET RS10235
gene id: 416591:TLET_RS10235
uniprot id: A8F8R0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

416591:TLET RS07375
gene id: 416591:TLET_RS07375
uniprot id: A8F761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS10470
gene id: 416591:TLET_RS10470
uniprot id: A8F8V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

416591:TLET RS04870
gene id: 416591:TLET_RS04870
uniprot id: A8F5T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

416591:TLET RS02825
gene id: 416591:TLET_RS02825
uniprot id: A8F4N4
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS08600
gene id: 416591:TLET_RS08600
uniprot id: A8F7U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS07370
gene id: 416591:TLET_RS07370
uniprot id: A8F760
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

416591:TLET RS01710
gene id: 416591:TLET_RS01710
uniprot id: A8F417
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

416591:TLET RS01445
gene id: 416591:TLET_RS01445
uniprot id: A8F3W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

416591:TLET RS08460
gene id: 416591:TLET_RS08460
uniprot id: A8F7R6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

416591:TLET RS02150
gene id: 416591:TLET_RS02150
uniprot id: A8F4A3
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

416591:TLET RS05860
gene id: 416591:TLET_RS05860
uniprot id: A8F6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS03115
gene id: 416591:TLET_RS03115
uniprot id: A8F4U2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

416591:TLET RS03570
gene id: 416591:TLET_RS03570
uniprot id: A8F533
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

416591:TLET RS02605
gene id: 416591:TLET_RS02605
uniprot id: A8F4J2
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS10095
gene id: 416591:TLET_RS10095
uniprot id: A8F8N2
names: Similarity
messages: Belongs to the pyruvate kinase family.

416591:TLET RS09235
gene id: 416591:TLET_RS09235
uniprot id: A8F868
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS00855
gene id: 416591:TLET_RS00855
uniprot id: A8F3K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

416591:TLET RS10575
gene id: 416591:TLET_RS10575
uniprot id: A8F8X9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

416591:TLET RS00240
gene id: 416591:TLET_RS00240
uniprot id: A8F383
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

416591:TLET RS04660
gene id: 416591:TLET_RS04660
uniprot id: A8F5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS07850
gene id: 416591:TLET_RS07850
uniprot id: A8F7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS04560
gene id: 416591:TLET_RS04560
uniprot id: A8F5M4
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS00195
gene id: 416591:TLET_RS00195
uniprot id: A8F375
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

416591:TLET RS03645
gene id: 416591:TLET_RS03645
uniprot id: A8F548
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

416591:TLET RS05510
gene id: 416591:TLET_RS05510
uniprot id: A8F658
names: Similarity
messages: Belongs to the CutA family.

416591:TLET RS01495
gene id: 416591:TLET_RS01495
uniprot id: A8F3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

416591:TLET RS10485
gene id: 416591:TLET_RS10485
uniprot id: A8F8W1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

416591:TLET RS03010
gene id: 416591:TLET_RS03010
uniprot id: A8F4S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

416591:TLET RS03065
gene id: 416591:TLET_RS03065
uniprot id: A8F4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

416591:TLET RS04780
gene id: 416591:TLET_RS04780
uniprot id: A8F5R3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS00645
gene id: 416591:TLET_RS00645
uniprot id: A8F3F9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

416591:TLET RS03020
gene id: 416591:TLET_RS03020
uniprot id: A8F4S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

416591:TLET RS00140
gene id: 416591:TLET_RS00140
uniprot id: A8F364
names: Similarity
messages: Belongs to the DapA family.

416591:TLET RS07650
gene id: 416591:TLET_RS07650
uniprot id: A8F7B1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

416591:TLET RS06825
gene id: 416591:TLET_RS06825
uniprot id: A8F6V8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

416591:TLET RS05275
gene id: 416591:TLET_RS05275
uniprot id: A8F612
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS08900
gene id: 416591:TLET_RS08900
uniprot id: A8F802
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

416591:TLET RS03455
gene id: 416591:TLET_RS03455
uniprot id: A8F510
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS02080
gene id: 416591:TLET_RS02080
uniprot id: A8F489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS08945
gene id: 416591:TLET_RS08945
uniprot id: A8F810
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

416591:TLET RS09525
gene id: 416591:TLET_RS09525
uniprot id: A8F8C5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS03985
gene id: 416591:TLET_RS03985
uniprot id: A8F5B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

416591:TLET RS08410
gene id: 416591:TLET_RS08410
uniprot id: A8F7Q7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

416591:TLET RS01805
gene id: 416591:TLET_RS01805
uniprot id: A8F436
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS05005
gene id: 416591:TLET_RS05005
uniprot id: A8F5V8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

416591:TLET RS08950
gene id: 416591:TLET_RS08950
uniprot id: A8F811
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

416591:TLET RS03800
gene id: 416591:TLET_RS03800
uniprot id: A8F576
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

416591:TLET RS01435
gene id: 416591:TLET_RS01435
uniprot id: A8F3W4
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

416591:TLET RS07435
gene id: 416591:TLET_RS07435
uniprot id: A8F772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

416591:TLET RS09135
gene id: 416591:TLET_RS09135
uniprot id: A8F848
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

416591:TLET RS10265
gene id: 416591:TLET_RS10265
uniprot id: A8F8R6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

416591:TLET RS10475
gene id: 416591:TLET_RS10475
uniprot id: A8F8V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

416591:TLET RS10035
gene id: 416591:TLET_RS10035
uniprot id: A8F8M0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Short' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

416591:TLET RS03095
gene id: 416591:TLET_RS03095
uniprot id: A8F4T8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

416591:TLET RS01760
gene id: 416591:TLET_RS01760
uniprot id: A8F427
names: Similarity
messages: Belongs to the LacAB/RpiB family.

416591:TLET RS10070
gene id: 416591:TLET_RS10070
uniprot id: A8F8M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

416591:TLET RS04450
gene id: 416591:TLET_RS04450
uniprot id: A8F5K2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

416591:TLET RS04235
gene id: 416591:TLET_RS04235
uniprot id: A8F5F9
names: Similarity
messages: Belongs to the carbamate kinase family.

416591:TLET RS08340
gene id: 416591:TLET_RS08340
uniprot id: A8F7P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

416591:TLET RS06600
gene id: 416591:TLET_RS06600
uniprot id: A8F6R3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

416591:TLET RS03440
gene id: 416591:TLET_RS03440
uniprot id: A8F507
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS08495
gene id: 416591:TLET_RS08495
uniprot id: A8F7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

416591:TLET RS06545
gene id: 416591:TLET_RS06545
uniprot id: A8F6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

416591:TLET RS03405
gene id: 416591:TLET_RS03405
uniprot id: A8F500
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

416591:TLET RS00975
gene id: 416591:TLET_RS00975
uniprot id: A8F3M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

416591:TLET RS03070
gene id: 416591:TLET_RS03070
uniprot id: A8F4T2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

416591:TLET RS08565
gene id: 416591:TLET_RS08565
uniprot id: A8F7T6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

416591:TLET RS04495
gene id: 416591:TLET_RS04495
uniprot id: A8F5L1
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

416591:TLET RS02940
gene id: 416591:TLET_RS02940
uniprot id: A8F4Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

416591:TLET RS03195
gene id: 416591:TLET_RS03195
uniprot id: A8F4V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

416591:TLET RS00035
gene id: 416591:TLET_RS00035
uniprot id: A8F348
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS01725
gene id: 416591:TLET_RS01725
uniprot id: A8F420
names: Similarity
messages: Belongs to the BMP lipoprotein family.

416591:TLET RS10425
gene id: 416591:TLET_RS10425
uniprot id: A8F8U9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

416591:TLET RS05250
gene id: 416591:TLET_RS05250
uniprot id: A8F607
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS03960
gene id: 416591:TLET_RS03960
uniprot id: A8F5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

416591:TLET RS08530
gene id: 416591:TLET_RS08530
uniprot id: A8F7T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

416591:TLET RS03105
gene id: 416591:TLET_RS03105
uniprot id: A8F4U0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

416591:TLET RS08020
gene id: 416591:TLET_RS08020
uniprot id: A8F7I2
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS01045
gene id: 416591:TLET_RS01045
uniprot id: A8F3N9
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

416591:TLET RS03475
gene id: 416591:TLET_RS03475
uniprot id: A8F514
names: Cofactor
messages: Binds 1 zinc ion per subunit.

416591:TLET RS06855
gene id: 416591:TLET_RS06855
uniprot id: A8F6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS03100
gene id: 416591:TLET_RS03100
uniprot id: A8F4T9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

416591:TLET RS00300
gene id: 416591:TLET_RS00300
uniprot id: A8F395
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

416591:TLET RS01080
gene id: 416591:TLET_RS01080
uniprot id: A8F3P6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

416591:TLET RS04665
gene id: 416591:TLET_RS04665
uniprot id: A8F5P5
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

416591:TLET RS09220
gene id: 416591:TLET_RS09220
uniprot id: A8F865
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

416591:TLET RS01485
gene id: 416591:TLET_RS01485
uniprot id: A8F3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

416591:TLET RS01770
gene id: 416591:TLET_RS01770
uniprot id: A8F429
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

416591:TLET RS03260
gene id: 416591:TLET_RS03260
uniprot id: A8F4X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

416591:TLET RS00830
gene id: 416591:TLET_RS00830
uniprot id: A8F3J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

416591:TLET RS04430
gene id: 416591:TLET_RS04430
uniprot id: A8F5J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

416591:TLET RS09405
gene id: 416591:TLET_RS09405
uniprot id: A8F8A1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

416591:TLET RS02290
gene id: 416591:TLET_RS02290
uniprot id: A8F4D1
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

416591:TLET RS03865
gene id: 416591:TLET_RS03865
uniprot id: A8F589
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

416591:TLET RS03675
gene id: 416591:TLET_RS03675
uniprot id: A8F554
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

416591:TLET RS00175
gene id: 416591:TLET_RS00175
uniprot id: A8F371
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS01405
gene id: 416591:TLET_RS01405
uniprot id: A8F3V9
names: Similarity
messages: Belongs to the Nth/MutY family.

416591:TLET RS02255
gene id: 416591:TLET_RS02255
uniprot id: A8F4C4
names: Similarity
messages: Belongs to the UPF0758 family.

416591:TLET RS01270
gene id: 416591:TLET_RS01270
uniprot id: A8F3T2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS03310
gene id: 416591:TLET_RS03310
uniprot id: A8F4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS03710
gene id: 416591:TLET_RS03710
uniprot id: A8F561
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS00450
gene id: 416591:TLET_RS00450
uniprot id: A8F3C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS01345
gene id: 416591:TLET_RS01345
uniprot id: A8F3U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

416591:TLET RS05125
gene id: 416591:TLET_RS05125
uniprot id: A8F5Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

416591:TLET RS04655
gene id: 416591:TLET_RS04655
uniprot id: A8F5P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

416591:TLET RS06630
gene id: 416591:TLET_RS06630
uniprot id: A8F6S0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

416591:TLET RS07465
gene id: 416591:TLET_RS07465
uniprot id: A8F778
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

416591:TLET RS04305
gene id: 416591:TLET_RS04305
uniprot id: A8F5H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

416591:TLET RS10480
gene id: 416591:TLET_RS10480
uniprot id: A8F8W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS03995
gene id: 416591:TLET_RS03995
uniprot id: A8F5B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

416591:TLET RS10600
gene id: 416591:TLET_RS10600
uniprot id: A8F366
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS08700
gene id: 416591:TLET_RS08700
uniprot id: A8F7W3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

416591:TLET RS01765
gene id: 416591:TLET_RS01765
uniprot id: A8F428
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

416591:TLET RS09145
gene id: 416591:TLET_RS09145
uniprot id: A8F850
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

416591:TLET RS04895
gene id: 416591:TLET_RS04895
uniprot id: A8F5T6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

416591:TLET RS07340
gene id: 416591:TLET_RS07340
uniprot id: A8F755
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

416591:TLET RS06990
gene id: 416591:TLET_RS06990
uniprot id: A8F6Y8
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

416591:TLET RS07015
gene id: 416591:TLET_RS07015
uniprot id: A8F6Z3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

416591:TLET RS09250
gene id: 416591:TLET_RS09250
uniprot id: A8F871
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

416591:TLET RS09855
gene id: 416591:TLET_RS09855
uniprot id: A8F8I7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

416591:TLET RS04985
gene id: 416591:TLET_RS04985
uniprot id: A8F5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

416591:TLET RS10330
gene id: 416591:TLET_RS10330
uniprot id: A8F8T0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

416591:TLET RS02385
gene id: 416591:TLET_RS02385
uniprot id: A8F4F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

416591:TLET RS01230
gene id: 416591:TLET_RS01230
uniprot id: A8F3S4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

416591:TLET RS08640
gene id: 416591:TLET_RS08640
uniprot id: A8F7V1
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

416591:TLET RS08220
gene id: 416591:TLET_RS08220
uniprot id: A8F7L9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

416591:TLET RS10240
gene id: 416591:TLET_RS10240
uniprot id: A8F8R1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

416591:TLET RS00780
gene id: 416591:TLET_RS00780
uniprot id: A8F3I6
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

416591:TLET RS04770
gene id: 416591:TLET_RS04770
uniprot id: A8F5R1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

416591:TLET RS05870
gene id: 416591:TLET_RS05870
uniprot id: A8F6C8
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

416591:TLET RS03855
gene id: 416591:TLET_RS03855
uniprot id: A8F587
names: Similarity
messages: Belongs to the methyltransferase superfamily. PrmA family.

416591:TLET RS04135
gene id: 416591:TLET_RS04135
uniprot id: A8F5E3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

416591:TLET RS05645
gene id: 416591:TLET_RS05645
uniprot id: A8F684
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

416591:TLET RS05355
gene id: 416591:TLET_RS05355
uniprot id: A8F627
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS02310
gene id: 416591:TLET_RS02310
uniprot id: A8F4D5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

416591:TLET RS03530
gene id: 416591:TLET_RS03530
uniprot id: A8F525
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

416591:TLET RS06735
gene id: 416591:TLET_RS06735
uniprot id: A8F6U0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

416591:TLET RS07795
gene id: 416591:TLET_RS07795
uniprot id: A8F7E0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

416591:TLET RS10560
gene id: 416591:TLET_RS10560
uniprot id: A8F8X6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

416591:TLET RS01910
gene id: 416591:TLET_RS01910
uniprot id: A8F456
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS03760
gene id: 416591:TLET_RS03760
uniprot id: A8F570
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

416591:TLET RS06715
gene id: 416591:TLET_RS06715
uniprot id: A8F6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

416591:TLET RS07745
gene id: 416591:TLET_RS07745
uniprot id: A8F7D0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

416591:TLET RS04835
gene id: 416591:TLET_RS04835
uniprot id: A8F5S4
names: Similarity
messages: Belongs to the peptidase S9C family.

416591:TLET RS03525
gene id: 416591:TLET_RS03525
uniprot id: A8F524
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

416591:TLET RS00200
gene id: 416591:TLET_RS00200
uniprot id: A8F376
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS01305
gene id: 416591:TLET_RS01305
uniprot id: A8F3T9
names: Similarity
messages: Belongs to the peptidase C40 family.

416591:TLET RS02465
gene id: 416591:TLET_RS02465
uniprot id: A8F4G4
names: Similarity
messages: Belongs to the peptidase U62 family.

416591:TLET RS00455
gene id: 416591:TLET_RS00455
uniprot id: A8F3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS09200
gene id: 416591:TLET_RS09200
uniprot id: A8F861
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS04040
gene id: 416591:TLET_RS04040
uniprot id: A8F5C4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

416591:TLET RS09585
gene id: 416591:TLET_RS09585
uniprot id: A8F8D6
names: Similarity
messages: Belongs to the UPF0047 family.

416591:TLET RS03900
gene id: 416591:TLET_RS03900
uniprot id: A8F596
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

416591:TLET RS08140
gene id: 416591:TLET_RS08140
uniprot id: A8F7K3
names: Similarity
messages: Belongs to the alkaline phosphatase family.

416591:TLET RS04080
gene id: 416591:TLET_RS04080
uniprot id: A8F5D2
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS05115
gene id: 416591:TLET_RS05115
uniprot id: A8F5Y0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

416591:TLET RS02800
gene id: 416591:TLET_RS02800
uniprot id: A8F4M9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

416591:TLET RS00295
gene id: 416591:TLET_RS00295
uniprot id: A8F394
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

416591:TLET RS10690
gene id: 416591:TLET_RS10690
uniprot id: A8F6M8
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS07640
gene id: 416591:TLET_RS07640
uniprot id: A8F7A9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

416591:TLET RS08325
gene id: 416591:TLET_RS08325
uniprot id: A8F7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

416591:TLET RS03075
gene id: 416591:TLET_RS03075
uniprot id: A8F4T3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

416591:TLET RS05385
gene id: 416591:TLET_RS05385
uniprot id: A8F633
names: Similarity
messages: Belongs to the GSP E family.

416591:TLET RS06485
gene id: 416591:TLET_RS06485
uniprot id: A8F6P1
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS08125
gene id: 416591:TLET_RS08125
uniprot id: A8F7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS09365
gene id: 416591:TLET_RS09365
uniprot id: A8F893
names: Similarity
messages: Belongs to the MotB family.

416591:TLET RS09170
gene id: 416591:TLET_RS09170
uniprot id: A8F855
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

416591:TLET RS02450
gene id: 416591:TLET_RS02450
uniprot id: A8F4G1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

416591:TLET RS05405
gene id: 416591:TLET_RS05405
uniprot id: A8F637
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

416591:TLET RS03410
gene id: 416591:TLET_RS03410
uniprot id: A8F501
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

416591:TLET RS07705
gene id: 416591:TLET_RS07705
uniprot id: A8F7C2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

416591:TLET RS10155
gene id: 416591:TLET_RS10155
uniprot id: A8F8P4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

416591:TLET RS10365
gene id: 416591:TLET_RS10365
uniprot id: A8F8T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

416591:TLET RS04585
gene id: 416591:TLET_RS04585
uniprot id: A8F5M9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

416591:TLET RS08745
gene id: 416591:TLET_RS08745
uniprot id: A8F7X2
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

416591:TLET RS03345
gene id: 416591:TLET_RS03345
uniprot id: A8F4Y8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

416591:TLET RS07880
gene id: 416591:TLET_RS07880
uniprot id: A8F7F7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

416591:TLET RS06850
gene id: 416591:TLET_RS06850
uniprot id: A8F6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS07040
gene id: 416591:TLET_RS07040
uniprot id: A8F6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

416591:TLET RS04355
gene id: 416591:TLET_RS04355
uniprot id: A8F5I3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

416591:TLET RS07570
gene id: 416591:TLET_RS07570
uniprot id: A8F799
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

416591:TLET RS01580
gene id: 416591:TLET_RS01580
uniprot id: A8F3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

416591:TLET RS07665
gene id: 416591:TLET_RS07665
uniprot id: A8F7B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

416591:TLET RS05075
gene id: 416591:TLET_RS05075
uniprot id: A8F5X2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

416591:TLET RS09155
gene id: 416591:TLET_RS09155
uniprot id: A8F852
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

416591:TLET RS07830
gene id: 416591:TLET_RS07830
uniprot id: A8F7E7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

416591:TLET RS03155
gene id: 416591:TLET_RS03155
uniprot id: A8F4V0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

416591:TLET RS02100
gene id: 416591:TLET_RS02100
uniprot id: A8F493
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

416591:TLET RS01420
gene id: 416591:TLET_RS01420
uniprot id: A8F3W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

416591:TLET RS10340
gene id: 416591:TLET_RS10340
uniprot id: A8F8T2
names: Similarity
messages: Belongs to the asp23 family.

416591:TLET RS09210
gene id: 416591:TLET_RS09210
uniprot id: A8F863
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

416591:TLET RS01705
gene id: 416591:TLET_RS01705
uniprot id: A8F416
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

416591:TLET RS05325
gene id: 416591:TLET_RS05325
uniprot id: A8F621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS08420
gene id: 416591:TLET_RS08420
uniprot id: A8F7Q9
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

416591:TLET RS04525
gene id: 416591:TLET_RS04525
uniprot id: A8F5L7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

416591:TLET RS04765
gene id: 416591:TLET_RS04765
uniprot id: A8F5R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

416591:TLET RS09890
gene id: 416591:TLET_RS09890
uniprot id: A8F8J4
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

416591:TLET RS08130
gene id: 416591:TLET_RS08130
uniprot id: A8F7K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

416591:TLET RS07225
gene id: 416591:TLET_RS07225
uniprot id: A8F732
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

416591:TLET RS03905
gene id: 416591:TLET_RS03905
uniprot id: A8F597
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

416591:TLET RS02395
gene id: 416591:TLET_RS02395
uniprot id: A8F4F2
names: Similarity
messages: Belongs to the AOR/FOR family.

416591:TLET RS07905
gene id: 416591:TLET_RS07905
uniprot id: A8F7G1
names: Similarity
messages: Belongs to the peptidase U62 family.

416591:TLET RS05270
gene id: 416591:TLET_RS05270
uniprot id: A8F611
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

416591:TLET RS05565
gene id: 416591:TLET_RS05565
uniprot id: A8F668
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

416591:TLET RS06085
gene id: 416591:TLET_RS06085
uniprot id: A8F6G9
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS08145
gene id: 416591:TLET_RS08145
uniprot id: A8F7K4
names: Similarity
messages: Belongs to the XFP family.

416591:TLET RS06625
gene id: 416591:TLET_RS06625
uniprot id: A8F6R9
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

416591:TLET RS01450
gene id: 416591:TLET_RS01450
uniprot id: A8F3W7
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

416591:TLET RS07750
gene id: 416591:TLET_RS07750
uniprot id: A8F7D1
names: Similarity
messages: Belongs to the peptidase M24B family.

416591:TLET RS09985
gene id: 416591:TLET_RS09985
uniprot id: A8F8L0
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS02925
gene id: 416591:TLET_RS02925
uniprot id: A8F4Q3
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS07625
gene id: 416591:TLET_RS07625
uniprot id: A8F7A7
names: Similarity
messages: Belongs to the peptidase S16 family.

416591:TLET RS03920
gene id: 416591:TLET_RS03920
uniprot id: A8F5A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

416591:TLET RS04485
gene id: 416591:TLET_RS04485
uniprot id: A8F5K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

416591:TLET RS00615
gene id: 416591:TLET_RS00615
uniprot id: A8F3F3
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

416591:TLET RS02025
gene id: 416591:TLET_RS02025
uniprot id: A8F478
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

416591:TLET RS00275
gene id: 416591:TLET_RS00275
uniprot id: A8F390
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

416591:TLET RS06335
gene id: 416591:TLET_RS06335
uniprot id: A8F6L3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

416591:TLET RS01830
gene id: 416591:TLET_RS01830
uniprot id: A8F441
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

416591:TLET RS10740
gene id: 416591:TLET_RS10740
uniprot id: A8F8X5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

416591:TLET RS10530
gene id: 416591:TLET_RS10530
uniprot id: A8F8X0
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS10490
gene id: 416591:TLET_RS10490
uniprot id: A8F8W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

416591:TLET RS07560
gene id: 416591:TLET_RS07560
uniprot id: A8F797
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

416591:TLET RS04750
gene id: 416591:TLET_RS04750
uniprot id: A8F5Q8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

416591:TLET RS09810
gene id: 416591:TLET_RS09810
uniprot id: A8F8H8
names: Similarity
messages: Belongs to the GARS family.

416591:TLET RS08040
gene id: 416591:TLET_RS08040
uniprot id: A8F7I5
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

416591:TLET RS05100
gene id: 416591:TLET_RS05100
uniprot id: A8F5X7
names: Similarity
messages: Belongs to the ComB family.

416591:TLET RS07770
gene id: 416591:TLET_RS07770
uniprot id: A8F7D5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

416591:TLET RS03730
gene id: 416591:TLET_RS03730
uniprot id: A8F564
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

416591:TLET RS07175
gene id: 416591:TLET_RS07175
uniprot id: A8F724
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

416591:TLET RS01895
gene id: 416591:TLET_RS01895
uniprot id: A8F453
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

416591:TLET RS02765
gene id: 416591:TLET_RS02765
uniprot id: A8F4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

416591:TLET RS01635
gene id: 416591:TLET_RS01635
uniprot id: A8F402
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

416591:TLET RS05415
gene id: 416591:TLET_RS05415
uniprot id: A8F639
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

416591:TLET RS08735
gene id: 416591:TLET_RS08735
uniprot id: A8F7X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS07950
gene id: 416591:TLET_RS07950
uniprot id: A8F7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS09795
gene id: 416591:TLET_RS09795
uniprot id: A8F8H5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

416591:TLET RS00340
gene id: 416591:TLET_RS00340
uniprot id: A8F3A3
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

416591:TLET RS03460
gene id: 416591:TLET_RS03460
uniprot id: A8F511
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS09410
gene id: 416591:TLET_RS09410
uniprot id: A8F8A2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

416591:TLET RS07180
gene id: 416591:TLET_RS07180
uniprot id: A8F725
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

416591:TLET RS05855
gene id: 416591:TLET_RS05855
uniprot id: A8F6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS10030
gene id: 416591:TLET_RS10030
uniprot id: A8F8L9
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.

416591:TLET RS10385
gene id: 416591:TLET_RS10385
uniprot id: A8F8U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

416591:TLET RS01860
gene id: 416591:TLET_RS01860
uniprot id: A8F446
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

416591:TLET RS06905
gene id: 416591:TLET_RS06905
uniprot id: A8F6X2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

416591:TLET RS02660
gene id: 416591:TLET_RS02660
uniprot id: A8F4K2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

416591:TLET RS09760
gene id: 416591:TLET_RS09760
uniprot id: A8F8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

416591:TLET RS03895
gene id: 416591:TLET_RS03895
uniprot id: A8F595
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS02855
gene id: 416591:TLET_RS02855
uniprot id: A8F4N9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

416591:TLET RS09070
gene id: 416591:TLET_RS09070
uniprot id: A8F835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

416591:TLET RS07995
gene id: 416591:TLET_RS07995
uniprot id: A8F7H7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

416591:TLET RS04535
gene id: 416591:TLET_RS04535
uniprot id: A8F5L9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS02875
gene id: 416591:TLET_RS02875
uniprot id: A8F4P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

416591:TLET RS00605
gene id: 416591:TLET_RS00605
uniprot id: A8F3F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS00725
gene id: 416591:TLET_RS00725
uniprot id: A8F3H5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

416591:TLET RS09800
gene id: 416591:TLET_RS09800
uniprot id: A8F8H6
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS08670
gene id: 416591:TLET_RS08670
uniprot id: A8F7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS09415
gene id: 416591:TLET_RS09415
uniprot id: A8F8A3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

416591:TLET RS05375
gene id: 416591:TLET_RS05375
uniprot id: A8F631
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

416591:TLET RS10310
gene id: 416591:TLET_RS10310
uniprot id: A8F8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS09875
gene id: 416591:TLET_RS09875
uniprot id: A8F8J1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS05105
gene id: 416591:TLET_RS05105
uniprot id: A8F5X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS00970
gene id: 416591:TLET_RS00970
uniprot id: A8F3M4
names: Similarity
messages: Belongs to the FGGY kinase family.

416591:TLET RS10665
gene id: 416591:TLET_RS10665
uniprot id: A8F655
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS01930
gene id: 416591:TLET_RS01930
uniprot id: A8F460
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

416591:TLET RS01880
gene id: 416591:TLET_RS01880
uniprot id: A8F450
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

416591:TLET RS06430
gene id: 416591:TLET_RS06430
uniprot id: A8F6N0
names: Similarity
messages: Belongs to the peptidase C15 family.

416591:TLET RS09085
gene id: 416591:TLET_RS09085
uniprot id: A8F838
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

416591:TLET RS05690
gene id: 416591:TLET_RS05690
uniprot id: A8F692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

416591:TLET RS08365
gene id: 416591:TLET_RS08365
uniprot id: A8F7P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

416591:TLET RS04875
gene id: 416591:TLET_RS04875
uniprot id: A8F5T2
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS00310
gene id: 416591:TLET_RS00310
uniprot id: A8F397
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

416591:TLET RS04805
gene id: 416591:TLET_RS04805
uniprot id: A8F5R8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

416591:TLET RS00215
gene id: 416591:TLET_RS00215
uniprot id: A8F378
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

416591:TLET RS04675
gene id: 416591:TLET_RS04675
uniprot id: A8F5P7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

416591:TLET RS10430
gene id: 416591:TLET_RS10430
uniprot id: A8F8V0
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

416591:TLET RS10180
gene id: 416591:TLET_RS10180
uniprot id: A8F8P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

416591:TLET RS01040
gene id: 416591:TLET_RS01040
uniprot id: A8F3N8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

416591:TLET RS01480
gene id: 416591:TLET_RS01480
uniprot id: A8F3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

416591:TLET RS08120
gene id: 416591:TLET_RS08120
uniprot id: A8F7J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS03185
gene id: 416591:TLET_RS03185
uniprot id: A8F4V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

416591:TLET RS01875
gene id: 416591:TLET_RS01875
uniprot id: A8F449
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

416591:TLET RS00420
gene id: 416591:TLET_RS00420
uniprot id: A8F3B9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

416591:TLET RS09450
gene id: 416591:TLET_RS09450
uniprot id: A8F8B0
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

416591:TLET RS02035
gene id: 416591:TLET_RS02035
uniprot id: A8F480
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

416591:TLET RS02950
gene id: 416591:TLET_RS02950
uniprot id: A8F4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

416591:TLET RS05805
gene id: 416591:TLET_RS05805
uniprot id: A8F6B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS03885
gene id: 416591:TLET_RS03885
uniprot id: A8F593
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS10075
gene id: 416591:TLET_RS10075
uniprot id: A8F8M8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

416591:TLET RS07580
gene id: 416591:TLET_RS07580
uniprot id: A8F7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

416591:TLET RS09345
gene id: 416591:TLET_RS09345
uniprot id: A8F889
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

416591:TLET RS06580
gene id: 416591:TLET_RS06580
uniprot id: A8F6Q9
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS09775
gene id: 416591:TLET_RS09775
uniprot id: A8F8H1
names: Subcellular Location Annotation
messages: Cytoplasm

416591:TLET RS04085
gene id: 416591:TLET_RS04085
uniprot id: A8F5D3
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS04015
gene id: 416591:TLET_RS04015
uniprot id: A8F5B9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

416591:TLET RS05630
gene id: 416591:TLET_RS05630
uniprot id: A8F681
names: Similarity
messages: Belongs to the UPF0173 family.

416591:TLET RS01185
gene id: 416591:TLET_RS01185
uniprot id: A8F3R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

416591:TLET RS05725
gene id: 416591:TLET_RS05725
uniprot id: A8F699
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

416591:TLET RS08615
gene id: 416591:TLET_RS08615
uniprot id: A8F7U6
names: Similarity
messages: Belongs to the peptidase C40 family.

416591:TLET RS00355
gene id: 416591:TLET_RS00355
uniprot id: A8F3A6
names: Similarity
messages: Belongs to the UPF0111 family.

416591:TLET RS03735
gene id: 416591:TLET_RS03735
uniprot id: A8F565
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

416591:TLET RS07150
gene id: 416591:TLET_RS07150
uniprot id: A8F720
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

416591:TLET RS02205
gene id: 416591:TLET_RS02205
uniprot id: A8F4B4
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS07140
gene id: 416591:TLET_RS07140
uniprot id: A8F718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

416591:TLET RS00865
gene id: 416591:TLET_RS00865
uniprot id: A8F3K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

416591:TLET RS03015
gene id: 416591:TLET_RS03015
uniprot id: A8F4S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

416591:TLET RS02935
gene id: 416591:TLET_RS02935
uniprot id: A8F4Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

416591:TLET RS02665
gene id: 416591:TLET_RS02665
uniprot id: A8F4K3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

416591:TLET RS09850
gene id: 416591:TLET_RS09850
uniprot id: A8F8I6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

416591:TLET RS06645
gene id: 416591:TLET_RS06645
uniprot id: A8F6S3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

416591:TLET RS09560
gene id: 416591:TLET_RS09560
uniprot id: A8F8D1
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS06405
gene id: 416591:TLET_RS06405
uniprot id: A8F6M6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 8 family.

416591:TLET RS01780
gene id: 416591:TLET_RS01780
uniprot id: A8F431
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

416591:TLET RS01475
gene id: 416591:TLET_RS01475
uniprot id: A8F3X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

416591:TLET RS03415
gene id: 416591:TLET_RS03415
uniprot id: A8F502
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

416591:TLET RS07215
gene id: 416591:TLET_RS07215
uniprot id: A8F730
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

416591:TLET RS07930
gene id: 416591:TLET_RS07930
uniprot id: A8F7G5
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

416591:TLET RS05665
gene id: 416591:TLET_RS05665
uniprot id: A8F687
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

416591:TLET RS06195
gene id: 416591:TLET_RS06195
uniprot id: A8F6I7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

416591:TLET RS07425
gene id: 416591:TLET_RS07425
uniprot id: A8F770
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

416591:TLET RS03950
gene id: 416591:TLET_RS03950
uniprot id: A8F5A6
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS09840
gene id: 416591:TLET_RS09840
uniprot id: A8F8I4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

416591:TLET RS03120
gene id: 416591:TLET_RS03120
uniprot id: A8F4U3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

416591:TLET RS01035
gene id: 416591:TLET_RS01035
uniprot id: A8F3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

416591:TLET RS02320
gene id: 416591:TLET_RS02320
uniprot id: A8F4D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

416591:TLET RS00995
gene id: 416591:TLET_RS00995
uniprot id: A8F3M9
names: Similarity
messages: Belongs to the archaeal-type GPI family.

416591:TLET RS01065
gene id: 416591:TLET_RS01065
uniprot id: A8F3P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

416591:TLET RS02040
gene id: 416591:TLET_RS02040
uniprot id: A8F481
names: Similarity
messages: Belongs to the peptidase S1C family.

416591:TLET RS10435
gene id: 416591:TLET_RS10435
uniprot id: A8F8V1
names: Similarity
messages: Belongs to the CTP synthase family.

416591:TLET RS08370
gene id: 416591:TLET_RS08370
uniprot id: A8F7P9
names: Similarity
messages: Belongs to the RemA family.

416591:TLET RS02380
gene id: 416591:TLET_RS02380
uniprot id: A8F4E9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

416591:TLET RS08525
gene id: 416591:TLET_RS08525
uniprot id: A8F7S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

416591:TLET RS04550
gene id: 416591:TLET_RS04550
uniprot id: A8F5M2
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS07945
gene id: 416591:TLET_RS07945
uniprot id: A8F7G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

416591:TLET RS07700
gene id: 416591:TLET_RS07700
uniprot id: A8F7C1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

416591:TLET RS01735
gene id: 416591:TLET_RS01735
uniprot id: A8F422
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS07775
gene id: 416591:TLET_RS07775
uniprot id: A8F7D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

416591:TLET RS08355
gene id: 416591:TLET_RS08355
uniprot id: A8F7P6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

416591:TLET RS07815
gene id: 416591:TLET_RS07815
uniprot id: A8F7E4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

416591:TLET RS09740
gene id: 416591:TLET_RS09740
uniprot id: A8F8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

416591:TLET RS03355
gene id: 416591:TLET_RS03355
uniprot id: A8F4Z0
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

416591:TLET RS05590
gene id: 416591:TLET_RS05590
uniprot id: A8F673
names: Subcellular Location Annotation
messages: Membrane

416591:TLET RS05120
gene id: 416591:TLET_RS05120
uniprot id: A8F5Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

416591:TLET RS00415
gene id: 416591:TLET_RS00415
uniprot id: A8F3B8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

416591:TLET RS03045
gene id: 416591:TLET_RS03045
uniprot id: A8F4S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

416591:TLET RS01175
gene id: 416591:TLET_RS01175
uniprot id: A8F3R3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.