414996:CDG81 RS20215
gene id: 414996:CDG81_RS20215
uniprot id: A0A099D9F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

414996:CDG81 RS23010
gene id: 414996:CDG81_RS23010
uniprot id: A0A099D9Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS16365
gene id: 414996:CDG81_RS16365
uniprot id: A0A099D6R3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS11185
gene id: 414996:CDG81_RS11185
uniprot id: A0A099D5W1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

414996:CDG81 RS09210
gene id: 414996:CDG81_RS09210
uniprot id: A0A099D7Y1
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS08110
gene id: 414996:CDG81_RS08110
uniprot id: A0A099D6H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

414996:CDG81 RS05410
gene id: 414996:CDG81_RS05410
uniprot id: A0A099D3A7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

414996:CDG81 RS07255
gene id: 414996:CDG81_RS07255
uniprot id: A0A099D6U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

414996:CDG81 RS01570
gene id: 414996:CDG81_RS01570
uniprot id: A0A099DBG6
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

414996:CDG81 RS15155
gene id: 414996:CDG81_RS15155
uniprot id: A0A099D6K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

414996:CDG81 RS00550
gene id: 414996:CDG81_RS00550
uniprot id: A0A099DAG2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

414996:CDG81 RS18205
gene id: 414996:CDG81_RS18205
uniprot id: A0A099D0X6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

414996:CDG81 RS13715
gene id: 414996:CDG81_RS13715
uniprot id: A0A099D5M5
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

414996:CDG81 RS17765
gene id: 414996:CDG81_RS17765
uniprot id: A0A099D154
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

414996:CDG81 RS06920
gene id: 414996:CDG81_RS06920
uniprot id: A0A099D8H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

414996:CDG81 RS16315
gene id: 414996:CDG81_RS16315
uniprot id: A0A099D4W7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

414996:CDG81 RS07045
gene id: 414996:CDG81_RS07045
uniprot id: A0A099D8G0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

414996:CDG81 RS08550
gene id: 414996:CDG81_RS08550
uniprot id: A0A099D7S4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS04735
gene id: 414996:CDG81_RS04735
uniprot id: A0A099D2B7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

414996:CDG81 RS12865
gene id: 414996:CDG81_RS12865
uniprot id: A0A099D4Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS22190
gene id: 414996:CDG81_RS22190
uniprot id: A0A099D9E2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS02705
gene id: 414996:CDG81_RS02705
uniprot id: A0A099D2W3
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
messages: Homodimer.

414996:CDG81 RS05110
gene id: 414996:CDG81_RS05110
uniprot id: A0A099D2L1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

414996:CDG81 RS11155
gene id: 414996:CDG81_RS11155
uniprot id: A0A099D6P6
names: Similarity
messages: Belongs to the universal stress protein A family.

414996:CDG81 RS15915
gene id: 414996:CDG81_RS15915
uniprot id: A0A099D4U5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS17195
gene id: 414996:CDG81_RS17195
uniprot id: A0A099D055
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

414996:CDG81 RS17750
gene id: 414996:CDG81_RS17750
uniprot id: A0A099D0W8
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

414996:CDG81 RS11975
gene id: 414996:CDG81_RS11975
uniprot id: A0A223RSN0
names: Similarity
messages: Belongs to the HisA/HisF family.

414996:CDG81 RS11500
gene id: 414996:CDG81_RS11500
uniprot id: A0A099D545
names: Subcellular Location Annotation
messages: Cytoplasm

414996:CDG81 RS18315
gene id: 414996:CDG81_RS18315
uniprot id: A0A099D8N8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

414996:CDG81 RS00195
gene id: 414996:CDG81_RS00195
uniprot id: A0A099DA90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS09765
gene id: 414996:CDG81_RS09765
uniprot id: A0A099D817
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

414996:CDG81 RS03715
gene id: 414996:CDG81_RS03715
uniprot id: A0A099D3D4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS14520
gene id: 414996:CDG81_RS14520
uniprot id: A0A099D4G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

414996:CDG81 RS19485
gene id: 414996:CDG81_RS19485
uniprot id: A0A099D8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

414996:CDG81 RS06730
gene id: 414996:CDG81_RS06730
uniprot id: A0A099D1K4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS06900
gene id: 414996:CDG81_RS06900
uniprot id: A0A099D6Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS13835
gene id: 414996:CDG81_RS13835
uniprot id: A0A099D3Y0
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS00035
gene id: 414996:CDG81_RS00035
uniprot id: A0A099DA37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

414996:CDG81 RS10045
gene id: 414996:CDG81_RS10045
uniprot id: A0A099D870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

414996:CDG81 RS12425
gene id: 414996:CDG81_RS12425
uniprot id: A0A099D5S6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

414996:CDG81 RS20665
gene id: 414996:CDG81_RS20665
uniprot id: A0A099D9B1
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS10030
gene id: 414996:CDG81_RS10030
uniprot id: A0A223RRR5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

414996:CDG81 RS17715
gene id: 414996:CDG81_RS17715
uniprot id: A0A099D066
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

414996:CDG81 RS22445
gene id: 414996:CDG81_RS22445
uniprot id: A0A099DBG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

414996:CDG81 RS14220
gene id: 414996:CDG81_RS14220
uniprot id: A0A099D5X2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS18120
gene id: 414996:CDG81_RS18120
uniprot id: A0A223RVF2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

414996:CDG81 RS03765
gene id: 414996:CDG81_RS03765
uniprot id: A0A099D3P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

414996:CDG81 RS09975
gene id: 414996:CDG81_RS09975
uniprot id: A0A099D6X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS16340
gene id: 414996:CDG81_RS16340
uniprot id: A0A099D6R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

414996:CDG81 RS22875
gene id: 414996:CDG81_RS22875
uniprot id: A0A099D9T8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

414996:CDG81 RS19595
gene id: 414996:CDG81_RS19595
uniprot id: A0A099D7P7
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

414996:CDG81 RS17695
gene id: 414996:CDG81_RS17695
uniprot id: A0A099D0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

414996:CDG81 RS09880
gene id: 414996:CDG81_RS09880
uniprot id: A0A099D7R6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

414996:CDG81 RS13690
gene id: 414996:CDG81_RS13690
uniprot id: A0A099D3M9
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

414996:CDG81 RS20885
gene id: 414996:CDG81_RS20885
uniprot id: A0A099DB61
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

414996:CDG81 RS13705
gene id: 414996:CDG81_RS13705
uniprot id: A0A099D3Z1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

414996:CDG81 RS08585
gene id: 414996:CDG81_RS08585
uniprot id: A0A099D7R7
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

414996:CDG81 RS19885
gene id: 414996:CDG81_RS19885
uniprot id: A0A099D9N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

414996:CDG81 RS02815
gene id: 414996:CDG81_RS02815
uniprot id: A0A099D2T9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS06385
gene id: 414996:CDG81_RS06385
uniprot id: A0A223RYG0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS15110
gene id: 414996:CDG81_RS15110
uniprot id: A0A099D4A5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

414996:CDG81 RS04090
gene id: 414996:CDG81_RS04090
uniprot id: A0A099D429
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

414996:CDG81 RS00815
gene id: 414996:CDG81_RS00815
uniprot id: A0A099DCN4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

414996:CDG81 RS22420
gene id: 414996:CDG81_RS22420
uniprot id: A0A099D9A7
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS07885
gene id: 414996:CDG81_RS07885
uniprot id: A0A099D8T2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

414996:CDG81 RS18930
gene id: 414996:CDG81_RS18930
uniprot id: A0A099D8Z5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

414996:CDG81 RS05135
gene id: 414996:CDG81_RS05135
uniprot id: A0A099D2M0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

414996:CDG81 RS19050
gene id: 414996:CDG81_RS19050
uniprot id: A0A099DA58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS15180
gene id: 414996:CDG81_RS15180
uniprot id: A0A099D6K0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

414996:CDG81 RS19530
gene id: 414996:CDG81_RS19530
uniprot id: A0A099D9Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

414996:CDG81 RS17150
gene id: 414996:CDG81_RS17150
uniprot id: A0A099D0P3
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS15450
gene id: 414996:CDG81_RS15450
uniprot id: A0A099D424
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS02360
gene id: 414996:CDG81_RS02360
uniprot id: A0A099D2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

414996:CDG81 RS14260
gene id: 414996:CDG81_RS14260
uniprot id: A0A099D4L0
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

414996:CDG81 RS00100
gene id: 414996:CDG81_RS00100
uniprot id: A0A223RXU3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

414996:CDG81 RS06250
gene id: 414996:CDG81_RS06250
uniprot id: A0A099D112
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

414996:CDG81 RS03655
gene id: 414996:CDG81_RS03655
uniprot id: A0A099D3R8
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS10800
gene id: 414996:CDG81_RS10800
uniprot id: A0A099D7S2
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS19940
gene id: 414996:CDG81_RS19940
uniprot id: A0A099D9A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

414996:CDG81 RS15820
gene id: 414996:CDG81_RS15820
uniprot id: A0A223RZ46
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS08035
gene id: 414996:CDG81_RS08035
uniprot id: A0A099D7I2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

414996:CDG81 RS22550
gene id: 414996:CDG81_RS22550
uniprot id: A0A099D991
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

414996:CDG81 RS06835
gene id: 414996:CDG81_RS06835
uniprot id: A0A099D719
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

414996:CDG81 RS03740
gene id: 414996:CDG81_RS03740
uniprot id: A0A099D3Q0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

414996:CDG81 RS04540
gene id: 414996:CDG81_RS04540
uniprot id: A0A099D1P2
names: Similarity
messages: Belongs to the asp23 family.

414996:CDG81 RS09070
gene id: 414996:CDG81_RS09070
uniprot id: A0A099D7Z8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

414996:CDG81 RS03240
gene id: 414996:CDG81_RS03240
uniprot id: A0A099D3B5
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS07755
gene id: 414996:CDG81_RS07755
uniprot id: A0A099D750
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

414996:CDG81 RS07505
gene id: 414996:CDG81_RS07505
uniprot id: A0A099D641
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS02905
gene id: 414996:CDG81_RS02905
uniprot id: A0A099D2D4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

414996:CDG81 RS18535
gene id: 414996:CDG81_RS18535
uniprot id: A0A223RVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

414996:CDG81 RS22025
gene id: 414996:CDG81_RS22025
uniprot id: A0A099DA89
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

414996:CDG81 RS15990
gene id: 414996:CDG81_RS15990
uniprot id: A0A099D6V7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

414996:CDG81 RS10355
gene id: 414996:CDG81_RS10355
uniprot id: A0A099D6A5
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS19835
gene id: 414996:CDG81_RS19835
uniprot id: A0A099D9C7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

414996:CDG81 RS05570
gene id: 414996:CDG81_RS05570
uniprot id: A0A223RPR4
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

414996:CDG81 RS23095
gene id: 414996:CDG81_RS23095
uniprot id: A0A099D9W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

414996:CDG81 RS00400
gene id: 414996:CDG81_RS00400
uniprot id: A0A099DB18
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

414996:CDG81 RS00515
gene id: 414996:CDG81_RS00515
uniprot id: A0A099DCD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

414996:CDG81 RS19625
gene id: 414996:CDG81_RS19625
uniprot id: A0A099D8N7
names: Similarity
messages: Belongs to the malate synthase family.

414996:CDG81 RS15690
gene id: 414996:CDG81_RS15690
uniprot id: A0A099D4D0
names: Similarity
messages: Belongs to the asp23 family.

414996:CDG81 RS15285
gene id: 414996:CDG81_RS15285
uniprot id: A0A099D579
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

414996:CDG81 RS04560
gene id: 414996:CDG81_RS04560
uniprot id: A0A099D2U2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

414996:CDG81 RS11395
gene id: 414996:CDG81_RS11395
uniprot id: A0A099D6W1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

414996:CDG81 RS05105
gene id: 414996:CDG81_RS05105
uniprot id: A0A099D274
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

414996:CDG81 RS19025
gene id: 414996:CDG81_RS19025
uniprot id: A0A099D899
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

414996:CDG81 RS15035
gene id: 414996:CDG81_RS15035
uniprot id: A0A223RU13
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

414996:CDG81 RS13195
gene id: 414996:CDG81_RS13195
uniprot id: A0A099D345
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

414996:CDG81 RS04275
gene id: 414996:CDG81_RS04275
uniprot id: A0A099D2Y0
names: Similarity
messages: Belongs to the thymidylate kinase family.

414996:CDG81 RS15710
gene id: 414996:CDG81_RS15710
uniprot id: A0A099D692
names: Similarity
messages: Belongs to the asp23 family.

414996:CDG81 RS10125
gene id: 414996:CDG81_RS10125
uniprot id: A0A099D6P1
names: Similarity
messages: Belongs to the peptidase S1 family.

414996:CDG81 RS18305
gene id: 414996:CDG81_RS18305
uniprot id: A0A099DAJ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

414996:CDG81 RS05980
gene id: 414996:CDG81_RS05980
uniprot id: A0A223RPX9
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS06990
gene id: 414996:CDG81_RS06990
uniprot id: A0A099D8G8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

414996:CDG81 RS03855
gene id: 414996:CDG81_RS03855
uniprot id: A0A099D504
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

414996:CDG81 RS01695
gene id: 414996:CDG81_RS01695
uniprot id: A0A099D243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS21415
gene id: 414996:CDG81_RS21415
uniprot id: A0A223RWZ3
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

414996:CDG81 RS06075
gene id: 414996:CDG81_RS06075
uniprot id: A0A099D0G1
names: Similarity
messages: Belongs to the HIBADH-related family.

414996:CDG81 RS18495
gene id: 414996:CDG81_RS18495
uniprot id: A0A099DAG3
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS00250
gene id: 414996:CDG81_RS00250
uniprot id: A0A099DA51
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS07770
gene id: 414996:CDG81_RS07770
uniprot id: A0A099D7C5
names: Similarity
messages: Belongs to the PspA/IM30 family.

414996:CDG81 RS23075
gene id: 414996:CDG81_RS23075
uniprot id: A0A099DB37
names: Similarity
messages: Belongs to the thioredoxin family.

414996:CDG81 RS15465
gene id: 414996:CDG81_RS15465
uniprot id: A0A099D6D8
names: Similarity
messages: Belongs to the CFA/CMAS family.

414996:CDG81 RS14845
gene id: 414996:CDG81_RS14845
uniprot id: A0A099D458
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

414996:CDG81 RS01740
gene id: 414996:CDG81_RS01740
uniprot id: A0A099D4J8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

414996:CDG81 RS15120
gene id: 414996:CDG81_RS15120
uniprot id: A0A223RU25
names: Similarity
messages: Belongs to the peptidase A24 family.

414996:CDG81 RS21605
gene id: 414996:CDG81_RS21605
uniprot id: A0A099DAH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

414996:CDG81 RS17485
gene id: 414996:CDG81_RS17485
uniprot id: A0A099D019
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

414996:CDG81 RS05915
gene id: 414996:CDG81_RS05915
uniprot id: A0A099D271
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

414996:CDG81 RS07145
gene id: 414996:CDG81_RS07145
uniprot id: A0A099D686
names: Similarity
messages: Belongs to the P(II) protein family.

414996:CDG81 RS11320
gene id: 414996:CDG81_RS11320
uniprot id: A0A223RSE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

414996:CDG81 RS07835
gene id: 414996:CDG81_RS07835
uniprot id: A0A099D8U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

414996:CDG81 RS19995
gene id: 414996:CDG81_RS19995
uniprot id: A0A099DAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

414996:CDG81 RS06300
gene id: 414996:CDG81_RS06300
uniprot id: A0A099D0J3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

414996:CDG81 RS16895
gene id: 414996:CDG81_RS16895
uniprot id: A0A223RUZ9
names: Similarity
messages: Belongs to the CdaR family.

414996:CDG81 RS07010
gene id: 414996:CDG81_RS07010
uniprot id: A0A099D795
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

414996:CDG81 RS20035
gene id: 414996:CDG81_RS20035
uniprot id: A0A099D8K3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

414996:CDG81 RS01605
gene id: 414996:CDG81_RS01605
uniprot id: A0A223RMW2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

414996:CDG81 RS16415
gene id: 414996:CDG81_RS16415
uniprot id: A0A099D541
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

414996:CDG81 RS10175
gene id: 414996:CDG81_RS10175
uniprot id: A0A099D626
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

414996:CDG81 RS15075
gene id: 414996:CDG81_RS15075
uniprot id: A0A223RUB6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

414996:CDG81 RS16600
gene id: 414996:CDG81_RS16600
uniprot id: A0A099D2D6
names: Similarity
messages: Belongs to the TPP enzyme family.

414996:CDG81 RS22510
gene id: 414996:CDG81_RS22510
uniprot id: A0A223RXJ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS19315
gene id: 414996:CDG81_RS19315
uniprot id: A0A099D8T0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

414996:CDG81 RS07995
gene id: 414996:CDG81_RS07995
uniprot id: A0A099D8R3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

414996:CDG81 RS19765
gene id: 414996:CDG81_RS19765
uniprot id: A0A099D8S7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

414996:CDG81 RS16245
gene id: 414996:CDG81_RS16245
uniprot id: A0A099D561
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS19605
gene id: 414996:CDG81_RS19605
uniprot id: A0A099D8B1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

414996:CDG81 RS09340
gene id: 414996:CDG81_RS09340
uniprot id: A0A099D9S4
names: Similarity
messages: Belongs to the WrbA family.

414996:CDG81 RS07485
gene id: 414996:CDG81_RS07485
uniprot id: A0A223RQQ1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

414996:CDG81 RS20360
gene id: 414996:CDG81_RS20360
uniprot id: A0A099DAL9
names: Similarity
messages: Belongs to the YoeB family.

414996:CDG81 RS07980
gene id: 414996:CDG81_RS07980
uniprot id: A0A099D7J3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

414996:CDG81 RS13700
gene id: 414996:CDG81_RS13700
uniprot id: A0A099D4B8
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS13735
gene id: 414996:CDG81_RS13735
uniprot id: A0A223RTH2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

414996:CDG81 RS01755
gene id: 414996:CDG81_RS01755
uniprot id: A0A223RN04
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

414996:CDG81 RS20890
gene id: 414996:CDG81_RS20890
uniprot id: A0A223RWS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

414996:CDG81 RS12230
gene id: 414996:CDG81_RS12230
uniprot id: A0A099D5E0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

414996:CDG81 RS05180
gene id: 414996:CDG81_RS05180
uniprot id: A0A099D292
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

414996:CDG81 RS09905
gene id: 414996:CDG81_RS09905
uniprot id: A0A099D7E5
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

414996:CDG81 RS05985
gene id: 414996:CDG81_RS05985
uniprot id: A0A099D1J5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

414996:CDG81 RS22320
gene id: 414996:CDG81_RS22320
uniprot id: A0A099DBI3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

414996:CDG81 RS05095
gene id: 414996:CDG81_RS05095
uniprot id: A0A099D1V6
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS17865
gene id: 414996:CDG81_RS17865
uniprot id: A0A223RVE6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS04485
gene id: 414996:CDG81_RS04485
uniprot id: A0A099D2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS15490
gene id: 414996:CDG81_RS15490
uniprot id: A0A099D6D2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

414996:CDG81 RS21455
gene id: 414996:CDG81_RS21455
uniprot id: A0A099DAX7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

414996:CDG81 RS19785
gene id: 414996:CDG81_RS19785
uniprot id: A0A099D904
names: Similarity
messages: Belongs to the WXG100 family.

414996:CDG81 RS08300
gene id: 414996:CDG81_RS08300
uniprot id: A0A099D6T0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

414996:CDG81 RS03645
gene id: 414996:CDG81_RS03645
uniprot id: A0A099D343
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

414996:CDG81 RS20460
gene id: 414996:CDG81_RS20460
uniprot id: A0A099D935
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

414996:CDG81 RS03795
gene id: 414996:CDG81_RS03795
uniprot id: A0A099D3N8
names: Similarity
messages: Belongs to the mycobacterial PPE family.

414996:CDG81 RS19390
gene id: 414996:CDG81_RS19390
uniprot id: A0A099D8R9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS16880
gene id: 414996:CDG81_RS16880
uniprot id: A0A099CZK7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

414996:CDG81 RS09900
gene id: 414996:CDG81_RS09900
uniprot id: A0A099D7R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

414996:CDG81 RS13520
gene id: 414996:CDG81_RS13520
uniprot id: A0A099D352
names: Similarity
messages: Belongs to the NodU/CmcH family.

414996:CDG81 RS02755
gene id: 414996:CDG81_RS02755
uniprot id: A0A223RND8
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS06880
gene id: 414996:CDG81_RS06880
uniprot id: A0A099D6C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

414996:CDG81 RS21385
gene id: 414996:CDG81_RS21385
uniprot id: A0A099D9H3
names: Similarity
messages: Belongs to the asparagine synthetase family.

414996:CDG81 RS08285
gene id: 414996:CDG81_RS08285
uniprot id: A0A223RQZ4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS19775
gene id: 414996:CDG81_RS19775
uniprot id: A0A099D9F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

414996:CDG81 RS16780
gene id: 414996:CDG81_RS16780
uniprot id: A0A099D0S3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

414996:CDG81 RS19030
gene id: 414996:CDG81_RS19030
uniprot id: A0A099D7X5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

414996:CDG81 RS22660
gene id: 414996:CDG81_RS22660
uniprot id: A0A099D9G3
names: Similarity
messages: Belongs to the peptidase S66 family.

414996:CDG81 RS22270
gene id: 414996:CDG81_RS22270
uniprot id: A0A099D9L7
names: Similarity
messages: Belongs to the GARS family.

414996:CDG81 RS10195
gene id: 414996:CDG81_RS10195
uniprot id: A0A099D705
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS06170
gene id: 414996:CDG81_RS06170
uniprot id: A0A099D100
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

414996:CDG81 RS15015
gene id: 414996:CDG81_RS15015
uniprot id: A0A099D530
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

414996:CDG81 RS11620
gene id: 414996:CDG81_RS11620
uniprot id: A0A099D7F6
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

414996:CDG81 RS08545
gene id: 414996:CDG81_RS08545
uniprot id: A0A099D844
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

414996:CDG81 RS00730
gene id: 414996:CDG81_RS00730
uniprot id: A0A099DCP5
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

414996:CDG81 RS01130
gene id: 414996:CDG81_RS01130
uniprot id: A0A099DB87
names: Similarity
messages: Belongs to the catalase family.

414996:CDG81 RS02875
gene id: 414996:CDG81_RS02875
uniprot id: A0A099D2E1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS14055
gene id: 414996:CDG81_RS14055
uniprot id: A0A099D603
names: Similarity
messages: Belongs to the peptidase M24B family.

414996:CDG81 RS12885
gene id: 414996:CDG81_RS12885
uniprot id: A0A099D5R8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

414996:CDG81 RS22900
gene id: 414996:CDG81_RS22900
uniprot id: A0A223RXN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

414996:CDG81 RS08740
gene id: 414996:CDG81_RS08740
uniprot id: A0A223RR65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS14875
gene id: 414996:CDG81_RS14875
uniprot id: A0A223RU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

414996:CDG81 RS05545
gene id: 414996:CDG81_RS05545
uniprot id: A0A099D203
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

414996:CDG81 RS11685
gene id: 414996:CDG81_RS11685
uniprot id: A0A099D5Y0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS09280
gene id: 414996:CDG81_RS09280
uniprot id: A0A099D7L7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

414996:CDG81 RS08195
gene id: 414996:CDG81_RS08195
uniprot id: A0A099D7F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

414996:CDG81 RS05175
gene id: 414996:CDG81_RS05175
uniprot id: A0A099D3Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

414996:CDG81 RS07565
gene id: 414996:CDG81_RS07565
uniprot id: A0A099D906
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS13145
gene id: 414996:CDG81_RS13145
uniprot id: A0A099D4T8
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS09255
gene id: 414996:CDG81_RS09255
uniprot id: A0A099D8K7
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

414996:CDG81 RS12360
gene id: 414996:CDG81_RS12360
uniprot id: A0A099D513
names: Similarity
messages: Belongs to the HsdR family.

414996:CDG81 RS05455
gene id: 414996:CDG81_RS05455
uniprot id: A0A099D0T2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

414996:CDG81 RS07180
gene id: 414996:CDG81_RS07180
uniprot id: A0A099D6V8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

414996:CDG81 RS18575
gene id: 414996:CDG81_RS18575
uniprot id: A0A099DAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS11260
gene id: 414996:CDG81_RS11260
uniprot id: A0A099D6B1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

414996:CDG81 RS15160
gene id: 414996:CDG81_RS15160
uniprot id: A0A099D4Q2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

414996:CDG81 RS17520
gene id: 414996:CDG81_RS17520
uniprot id: A0A099D0T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

414996:CDG81 RS11295
gene id: 414996:CDG81_RS11295
uniprot id: A0A099D6B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS08050
gene id: 414996:CDG81_RS08050
uniprot id: A0A099D6Y4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

414996:CDG81 RS02230
gene id: 414996:CDG81_RS02230
uniprot id: A0A099D297
names: Similarity
messages: Belongs to the EspG family.

414996:CDG81 RS14995
gene id: 414996:CDG81_RS14995
uniprot id: A0A223RU00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

414996:CDG81 RS18080
gene id: 414996:CDG81_RS18080
uniprot id: A0A099D0S7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

414996:CDG81 RS11060
gene id: 414996:CDG81_RS11060
uniprot id: A0A099D649
names: Similarity
messages: Belongs to the universal stress protein A family.

414996:CDG81 RS04455
gene id: 414996:CDG81_RS04455
uniprot id: A0A099D2D2
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

414996:CDG81 RS05155
gene id: 414996:CDG81_RS05155
uniprot id: A0A099D290
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS07330
gene id: 414996:CDG81_RS07330
uniprot id: A0A099D743
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

414996:CDG81 RS15955
gene id: 414996:CDG81_RS15955
uniprot id: A0A099D503
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS09095
gene id: 414996:CDG81_RS09095
uniprot id: A0A099D7Z5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS16680
gene id: 414996:CDG81_RS16680
uniprot id: A0A099D0A5
names: Similarity
messages: Belongs to the peptidase S58 family.

414996:CDG81 RS05755
gene id: 414996:CDG81_RS05755
uniprot id: A0A099D1F3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

414996:CDG81 RS01770
gene id: 414996:CDG81_RS01770
uniprot id: A0A099D2S9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

414996:CDG81 RS11910
gene id: 414996:CDG81_RS11910
uniprot id: A0A223RSN1
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

414996:CDG81 RS05360
gene id: 414996:CDG81_RS05360
uniprot id: A0A099D214
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

414996:CDG81 RS15135
gene id: 414996:CDG81_RS15135
uniprot id: A0A099D4Q7
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS03570
gene id: 414996:CDG81_RS03570
uniprot id: A0A099D2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

414996:CDG81 RS07670
gene id: 414996:CDG81_RS07670
uniprot id: A0A099D8Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

414996:CDG81 RS07200
gene id: 414996:CDG81_RS07200
uniprot id: A0A099D765
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

414996:CDG81 RS19155
gene id: 414996:CDG81_RS19155
uniprot id: A0A223RVY4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS05505
gene id: 414996:CDG81_RS05505
uniprot id: A0A099D1N5
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

414996:CDG81 RS22030
gene id: 414996:CDG81_RS22030
uniprot id: A0A223RXP2
names: Similarity
messages: Belongs to the IucA/IucC family.

414996:CDG81 RS04770
gene id: 414996:CDG81_RS04770
uniprot id: A0A099D2C4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

414996:CDG81 RS07615
gene id: 414996:CDG81_RS07615
uniprot id: A0A099D7F7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

414996:CDG81 RS04245
gene id: 414996:CDG81_RS04245
uniprot id: A0A099D3D8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

414996:CDG81 RS02075
gene id: 414996:CDG81_RS02075
uniprot id: A0A099D2C2
names: Similarity
messages: Belongs to the pirin family.

414996:CDG81 RS04460
gene id: 414996:CDG81_RS04460
uniprot id: A0A099D2S6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

414996:CDG81 RS07540
gene id: 414996:CDG81_RS07540
uniprot id: A0A099D911
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

414996:CDG81 RS22280
gene id: 414996:CDG81_RS22280
uniprot id: A0A099DAH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

414996:CDG81 RS16055
gene id: 414996:CDG81_RS16055
uniprot id: A0A099D6V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS02270
gene id: 414996:CDG81_RS02270
uniprot id: A0A099D2J8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS11875
gene id: 414996:CDG81_RS11875
uniprot id: A0A099D4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS09360
gene id: 414996:CDG81_RS09360
uniprot id: A0A099D863
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS01530
gene id: 414996:CDG81_RS01530
uniprot id: A0A099DAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

414996:CDG81 RS19810
gene id: 414996:CDG81_RS19810
uniprot id: A0A223RW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS06985
gene id: 414996:CDG81_RS06985
uniprot id: A0A223RQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

414996:CDG81 RS06740
gene id: 414996:CDG81_RS06740
uniprot id: A0A099D0R6
names: Similarity
messages: Belongs to the glutamine synthetase family.

414996:CDG81 RS15415
gene id: 414996:CDG81_RS15415
uniprot id: A0A099D4J2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

414996:CDG81 RS14475
gene id: 414996:CDG81_RS14475
uniprot id: A0A223RTY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS12035
gene id: 414996:CDG81_RS12035
uniprot id: A0A223RSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS20900
gene id: 414996:CDG81_RS20900
uniprot id: A0A223RZJ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS03770
gene id: 414996:CDG81_RS03770
uniprot id: A0A223RNV7
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS04400
gene id: 414996:CDG81_RS04400
uniprot id: A0A099D2C5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

414996:CDG81 RS05705
gene id: 414996:CDG81_RS05705
uniprot id: A0A099D3F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

414996:CDG81 RS11925
gene id: 414996:CDG81_RS11925
uniprot id: A0A223RYY9
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS01360
gene id: 414996:CDG81_RS01360
uniprot id: A0A099DB59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS07310
gene id: 414996:CDG81_RS07310
uniprot id: A0A099D6T3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

414996:CDG81 RS14160
gene id: 414996:CDG81_RS14160
uniprot id: A0A099D4B2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

414996:CDG81 RS22820
gene id: 414996:CDG81_RS22820
uniprot id: A0A099D9E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

414996:CDG81 RS07155
gene id: 414996:CDG81_RS07155
uniprot id: A0A099D6W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

414996:CDG81 RS05565
gene id: 414996:CDG81_RS05565
uniprot id: A0A223RPV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS07065
gene id: 414996:CDG81_RS07065
uniprot id: A0A099D6X7
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

414996:CDG81 RS19840
gene id: 414996:CDG81_RS19840
uniprot id: A0A099DAW5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

414996:CDG81 RS08355
gene id: 414996:CDG81_RS08355
uniprot id: A0A099D7Z0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

414996:CDG81 RS22155
gene id: 414996:CDG81_RS22155
uniprot id: A0A099D9N6
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS18555
gene id: 414996:CDG81_RS18555
uniprot id: A0A099D8J6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

414996:CDG81 RS09195
gene id: 414996:CDG81_RS09195
uniprot id: A0A099D8L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

414996:CDG81 RS17790
gene id: 414996:CDG81_RS17790
uniprot id: A0A099D150
names: Similarity
messages: Belongs to the YciI family.

414996:CDG81 RS00565
gene id: 414996:CDG81_RS00565
uniprot id: A0A099DBD4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS07890
gene id: 414996:CDG81_RS07890
uniprot id: A0A099D718
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

414996:CDG81 RS06895
gene id: 414996:CDG81_RS06895
uniprot id: A0A099D8I2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

414996:CDG81 RS07625
gene id: 414996:CDG81_RS07625
uniprot id: A0A099D780
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

414996:CDG81 RS06700
gene id: 414996:CDG81_RS06700
uniprot id: A0A099D395
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

414996:CDG81 RS22805
gene id: 414996:CDG81_RS22805
uniprot id: A0A099DA87
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS18430
gene id: 414996:CDG81_RS18430
uniprot id: A0A099D8X2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS11290
gene id: 414996:CDG81_RS11290
uniprot id: A0A223RSB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

414996:CDG81 RS15925
gene id: 414996:CDG81_RS15925
uniprot id: A0A099D6W7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

414996:CDG81 RS08370
gene id: 414996:CDG81_RS08370
uniprot id: A0A099D7D6
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

414996:CDG81 RS05920
gene id: 414996:CDG81_RS05920
uniprot id: A0A099D119
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

414996:CDG81 RS05345
gene id: 414996:CDG81_RS05345
uniprot id: A0A099D2B2
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

414996:CDG81 RS09045
gene id: 414996:CDG81_RS09045
uniprot id: A0A099D7U3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

414996:CDG81 RS14400
gene id: 414996:CDG81_RS14400
uniprot id: A0A099D3U3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

414996:CDG81 RS13435
gene id: 414996:CDG81_RS13435
uniprot id: A0A099D358
names: Similarity
messages: Belongs to the HsdR family.

414996:CDG81 RS20635
gene id: 414996:CDG81_RS20635
uniprot id: A0A099D9B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

414996:CDG81 RS20985
gene id: 414996:CDG81_RS20985
uniprot id: A0A099DA03
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

414996:CDG81 RS16655
gene id: 414996:CDG81_RS16655
uniprot id: A0A099D0B0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

414996:CDG81 RS15755
gene id: 414996:CDG81_RS15755
uniprot id: A0A099D4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

414996:CDG81 RS21620
gene id: 414996:CDG81_RS21620
uniprot id: A0A099D9N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

414996:CDG81 RS05740
gene id: 414996:CDG81_RS05740
uniprot id: A0A099D1S8
names: Similarity
messages: Belongs to the peptidase M1 family.

414996:CDG81 RS09915
gene id: 414996:CDG81_RS09915
uniprot id: A0A223RRP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

414996:CDG81 RS03500
gene id: 414996:CDG81_RS03500
uniprot id: A0A223RP33
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS05540
gene id: 414996:CDG81_RS05540
uniprot id: A0A099D1P1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

414996:CDG81 RS10080
gene id: 414996:CDG81_RS10080
uniprot id: A0A099D6Z0
names: Similarity
messages: Belongs to the CutA family.

414996:CDG81 RS07285
gene id: 414996:CDG81_RS07285
uniprot id: A0A099D6T9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS17630
gene id: 414996:CDG81_RS17630
uniprot id: A0A099D2R0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

414996:CDG81 RS06585
gene id: 414996:CDG81_RS06585
uniprot id: A0A223RYE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

414996:CDG81 RS09510
gene id: 414996:CDG81_RS09510
uniprot id: A0A099D7V3
names: Similarity
messages: Belongs to the universal stress protein A family.

414996:CDG81 RS05855
gene id: 414996:CDG81_RS05855
uniprot id: A0A099D107
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

414996:CDG81 RS22355
gene id: 414996:CDG81_RS22355
uniprot id: A0A099D9K2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

414996:CDG81 RS13305
gene id: 414996:CDG81_RS13305
uniprot id: A0A223RTC0
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS00825
gene id: 414996:CDG81_RS00825
uniprot id: A0A099DAJ6
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

414996:CDG81 RS06260
gene id: 414996:CDG81_RS06260
uniprot id: A0A099D1B6
names: Similarity
messages: Belongs to the Fur family.

414996:CDG81 RS06240
gene id: 414996:CDG81_RS06240
uniprot id: A0A099D1P0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

414996:CDG81 RS03955
gene id: 414996:CDG81_RS03955
uniprot id: A0A099D3K5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

414996:CDG81 RS14150
gene id: 414996:CDG81_RS14150
uniprot id: A0A099D3L8
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

414996:CDG81 RS18940
gene id: 414996:CDG81_RS18940
uniprot id: A0A099DA79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

414996:CDG81 RS04085
gene id: 414996:CDG81_RS04085
uniprot id: A0A099D316
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

414996:CDG81 RS07845
gene id: 414996:CDG81_RS07845
uniprot id: A0A099D6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

414996:CDG81 RS05100
gene id: 414996:CDG81_RS05100
uniprot id: A0A099D3V5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

414996:CDG81 RS06095
gene id: 414996:CDG81_RS06095
uniprot id: A0A099D2Z8
names: Similarity
messages: Belongs to the YciI family.

414996:CDG81 RS07605
gene id: 414996:CDG81_RS07605
uniprot id: A0A099D7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

414996:CDG81 RS03670
gene id: 414996:CDG81_RS03670
uniprot id: A0A099D336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS19235
gene id: 414996:CDG81_RS19235
uniprot id: A0A099DA29
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

414996:CDG81 RS21100
gene id: 414996:CDG81_RS21100
uniprot id: A0A099DB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

414996:CDG81 RS06440
gene id: 414996:CDG81_RS06440
uniprot id: A0A099D1S5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

414996:CDG81 RS07050
gene id: 414996:CDG81_RS07050
uniprot id: A0A099D6N3
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

414996:CDG81 RS14485
gene id: 414996:CDG81_RS14485
uniprot id: A0A099D3S9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

414996:CDG81 RS03300
gene id: 414996:CDG81_RS03300
uniprot id: A0A099D263
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS02405
gene id: 414996:CDG81_RS02405
uniprot id: A0A099D1T9
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS02365
gene id: 414996:CDG81_RS02365
uniprot id: A0A099D4A4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

414996:CDG81 RS20840
gene id: 414996:CDG81_RS20840
uniprot id: A0A099DA19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS08405
gene id: 414996:CDG81_RS08405
uniprot id: A0A099D8A1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

414996:CDG81 RS11280
gene id: 414996:CDG81_RS11280
uniprot id: A0A099D6U5
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

414996:CDG81 RS23120
gene id: 414996:CDG81_RS23120
uniprot id: A0A099D9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

414996:CDG81 RS15025
gene id: 414996:CDG81_RS15025
uniprot id: A0A223RU50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

414996:CDG81 RS07490
gene id: 414996:CDG81_RS07490
uniprot id: A0A099D8A0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

414996:CDG81 RS10895
gene id: 414996:CDG81_RS10895
uniprot id: A0A099D6A7
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS12430
gene id: 414996:CDG81_RS12430
uniprot id: A0A223RSV9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

414996:CDG81 RS03480
gene id: 414996:CDG81_RS03480
uniprot id: A0A099D3I9
names: Similarity
messages: Belongs to the catalase family.

414996:CDG81 RS05000
gene id: 414996:CDG81_RS05000
uniprot id: A0A099D1U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

414996:CDG81 RS20255
gene id: 414996:CDG81_RS20255
uniprot id: A0A099DAN8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS08115
gene id: 414996:CDG81_RS08115
uniprot id: A0A099D7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

414996:CDG81 RS11670
gene id: 414996:CDG81_RS11670
uniprot id: A0A099D580
names: Similarity
messages: Belongs to the CsoR family.

414996:CDG81 RS08215
gene id: 414996:CDG81_RS08215
uniprot id: A0A099D6U7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS22560
gene id: 414996:CDG81_RS22560
uniprot id: A0A099D9Z7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

414996:CDG81 RS11250
gene id: 414996:CDG81_RS11250
uniprot id: A0A099D5X5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS03450
gene id: 414996:CDG81_RS03450
uniprot id: A0A099D3J6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

414996:CDG81 RS11465
gene id: 414996:CDG81_RS11465
uniprot id: A0A099D600
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS07305
gene id: 414996:CDG81_RS07305
uniprot id: A0A099D747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

414996:CDG81 RS09730
gene id: 414996:CDG81_RS09730
uniprot id: A0A223RRQ0
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

414996:CDG81 RS03460
gene id: 414996:CDG81_RS03460
uniprot id: A0A099D386
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

414996:CDG81 RS06995
gene id: 414996:CDG81_RS06995
uniprot id: A0A099D6P2
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

414996:CDG81 RS19120
gene id: 414996:CDG81_RS19120
uniprot id: A0A223RVY7
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS18380
gene id: 414996:CDG81_RS18380
uniprot id: A0A099DAI7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS18510
gene id: 414996:CDG81_RS18510
uniprot id: A0A099D976
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

414996:CDG81 RS15810
gene id: 414996:CDG81_RS15810
uniprot id: A0A099D4X0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

414996:CDG81 RS17210
gene id: 414996:CDG81_RS17210
uniprot id: A0A099D2N7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

414996:CDG81 RS11565
gene id: 414996:CDG81_RS11565
uniprot id: A0A099D5V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

414996:CDG81 RS15150
gene id: 414996:CDG81_RS15150
uniprot id: A0A099D4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

414996:CDG81 RS15270
gene id: 414996:CDG81_RS15270
uniprot id: A0A099D6I2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

414996:CDG81 RS05195
gene id: 414996:CDG81_RS05195
uniprot id: A0A099D1Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

414996:CDG81 RS15585
gene id: 414996:CDG81_RS15585
uniprot id: A0A099D515
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

414996:CDG81 RS04760
gene id: 414996:CDG81_RS04760
uniprot id: A0A099D3N5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

414996:CDG81 RS13485
gene id: 414996:CDG81_RS13485
uniprot id: A0A099D470
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

414996:CDG81 RS01600
gene id: 414996:CDG81_RS01600
uniprot id: A0A099DCF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

414996:CDG81 RS20210
gene id: 414996:CDG81_RS20210
uniprot id: A0A099D8G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

414996:CDG81 RS08010
gene id: 414996:CDG81_RS08010
uniprot id: A0A099D7I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS14500
gene id: 414996:CDG81_RS14500
uniprot id: A0A099D450
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS01660
gene id: 414996:CDG81_RS01660
uniprot id: A0A099DCE5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

414996:CDG81 RS18150
gene id: 414996:CDG81_RS18150
uniprot id: A0A099D093
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS06225
gene id: 414996:CDG81_RS06225
uniprot id: A0A099D321
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

414996:CDG81 RS09275
gene id: 414996:CDG81_RS09275
uniprot id: A0A099D7X6
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

414996:CDG81 RS09790
gene id: 414996:CDG81_RS09790
uniprot id: A0A099D815
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

414996:CDG81 RS16155
gene id: 414996:CDG81_RS16155
uniprot id: A0A099D5J1
names: Caution
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS14865
gene id: 414996:CDG81_RS14865
uniprot id: A0A223RU28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

414996:CDG81 RS19460
gene id: 414996:CDG81_RS19460
uniprot id: A0A099D8D3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS07240
gene id: 414996:CDG81_RS07240
uniprot id: A0A099D6K6
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

414996:CDG81 RS16695
gene id: 414996:CDG81_RS16695
uniprot id: A0A099D0H9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

414996:CDG81 RS12970
gene id: 414996:CDG81_RS12970
uniprot id: A0A099D560
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

414996:CDG81 RS01545
gene id: 414996:CDG81_RS01545
uniprot id: A0A099DBH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

414996:CDG81 RS09545
gene id: 414996:CDG81_RS09545
uniprot id: A0A223RRI6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

414996:CDG81 RS08180
gene id: 414996:CDG81_RS08180
uniprot id: A0A099D8M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS19910
gene id: 414996:CDG81_RS19910
uniprot id: A0A099D9M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

414996:CDG81 RS15300
gene id: 414996:CDG81_RS15300
uniprot id: A0A099D4L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

414996:CDG81 RS05285
gene id: 414996:CDG81_RS05285
uniprot id: A0A099D2P6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

414996:CDG81 RS04520
gene id: 414996:CDG81_RS04520
uniprot id: A0A099D238
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

414996:CDG81 RS20995
gene id: 414996:CDG81_RS20995
uniprot id: A0A099DB50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

414996:CDG81 RS13910
gene id: 414996:CDG81_RS13910
uniprot id: A0A099D3X2
names: Similarity
messages: Belongs to the peptidase C40 family.

414996:CDG81 RS18115
gene id: 414996:CDG81_RS18115
uniprot id: A0A099D094
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

414996:CDG81 RS14085
gene id: 414996:CDG81_RS14085
uniprot id: A0A099D3Z7
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

414996:CDG81 RS15305
gene id: 414996:CDG81_RS15305
uniprot id: A0A099D461
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

414996:CDG81 RS06860
gene id: 414996:CDG81_RS06860
uniprot id: A0A099D715
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS19935
gene id: 414996:CDG81_RS19935
uniprot id: A0A099D9L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

414996:CDG81 RS07665
gene id: 414996:CDG81_RS07665
uniprot id: A0A099D7E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

414996:CDG81 RS07720
gene id: 414996:CDG81_RS07720
uniprot id: A0A223RQQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

414996:CDG81 RS22645
gene id: 414996:CDG81_RS22645
uniprot id: A0A099DBD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS20450
gene id: 414996:CDG81_RS20450
uniprot id: A0A099DBA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

414996:CDG81 RS22810
gene id: 414996:CDG81_RS22810
uniprot id: A0A099D9V3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

414996:CDG81 RS12160
gene id: 414996:CDG81_RS12160
uniprot id: A0A223RST4
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

414996:CDG81 RS16025
gene id: 414996:CDG81_RS16025
uniprot id: A0A099D587
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

414996:CDG81 RS03630
gene id: 414996:CDG81_RS03630
uniprot id: A0A099D3S4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

414996:CDG81 RS08360
gene id: 414996:CDG81_RS08360
uniprot id: A0A099D9J9
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

414996:CDG81 RS18840
gene id: 414996:CDG81_RS18840
uniprot id: A0A099DAA0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS22795
gene id: 414996:CDG81_RS22795
uniprot id: A0A099D955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS18765
gene id: 414996:CDG81_RS18765
uniprot id: A0A223RVS9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

414996:CDG81 RS21855
gene id: 414996:CDG81_RS21855
uniprot id: A0A099DAR1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS20955
gene id: 414996:CDG81_RS20955
uniprot id: A0A099DA07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

414996:CDG81 RS12460
gene id: 414996:CDG81_RS12460
uniprot id: A0A099D527
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS07350
gene id: 414996:CDG81_RS07350
uniprot id: A0A099D658
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

414996:CDG81 RS16725
gene id: 414996:CDG81_RS16725
uniprot id: A0A099D0H3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

414996:CDG81 RS22310
gene id: 414996:CDG81_RS22310
uniprot id: A0A099DAG6
names: Similarity
messages: Belongs to the YciI family.

414996:CDG81 RS19915
gene id: 414996:CDG81_RS19915
uniprot id: A0A099D9A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

414996:CDG81 RS01235
gene id: 414996:CDG81_RS01235
uniprot id: A0A099DB75
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS00010
gene id: 414996:CDG81_RS00010
uniprot id: A0A099DA41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

414996:CDG81 RS18350
gene id: 414996:CDG81_RS18350
uniprot id: A0A099D8N2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

414996:CDG81 RS02460
gene id: 414996:CDG81_RS02460
uniprot id: A0A099D1T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

414996:CDG81 RS03045
gene id: 414996:CDG81_RS03045
uniprot id: A0A099D3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS15190
gene id: 414996:CDG81_RS15190
uniprot id: A0A099D487
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS08435
gene id: 414996:CDG81_RS08435
uniprot id: A0A099D7V1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

414996:CDG81 RS00425
gene id: 414996:CDG81_RS00425
uniprot id: A0A099DB14
names: Similarity
messages: Belongs to the mycobacterial PPE family.

414996:CDG81 RS05220
gene id: 414996:CDG81_RS05220
uniprot id: A0A099D1Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS14345
gene id: 414996:CDG81_RS14345
uniprot id: A0A099D5V2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

414996:CDG81 RS16500
gene id: 414996:CDG81_RS16500
uniprot id: A0A099D0Z5
names: Similarity
messages: Belongs to the CdaR family.

414996:CDG81 RS15105
gene id: 414996:CDG81_RS15105
uniprot id: A0A099D4R4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS01885
gene id: 414996:CDG81_RS01885
uniprot id: A0A099D2Q9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

414996:CDG81 RS06400
gene id: 414996:CDG81_RS06400
uniprot id: A0A223RQ51
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

414996:CDG81 RS01830
gene id: 414996:CDG81_RS01830
uniprot id: A0A099D369
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

414996:CDG81 RS20365
gene id: 414996:CDG81_RS20365
uniprot id: A0A099D8Q1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

414996:CDG81 RS16020
gene id: 414996:CDG81_RS16020
uniprot id: A0A223RUR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS14320
gene id: 414996:CDG81_RS14320
uniprot id: A0A099D5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS02515
gene id: 414996:CDG81_RS02515
uniprot id: A0A099D264
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

414996:CDG81 RS15965
gene id: 414996:CDG81_RS15965
uniprot id: A0A099D5L3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

414996:CDG81 RS02320
gene id: 414996:CDG81_RS02320
uniprot id: A0A099D1V0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

414996:CDG81 RS16775
gene id: 414996:CDG81_RS16775
uniprot id: A0A099CZN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

414996:CDG81 RS13135
gene id: 414996:CDG81_RS13135
uniprot id: A0A099D5H5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

414996:CDG81 RS05240
gene id: 414996:CDG81_RS05240
uniprot id: A0A099D1J8
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

414996:CDG81 RS05875
gene id: 414996:CDG81_RS05875
uniprot id: A0A099D1V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

414996:CDG81 RS15115
gene id: 414996:CDG81_RS15115
uniprot id: A0A099D5B2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

414996:CDG81 RS18360
gene id: 414996:CDG81_RS18360
uniprot id: A0A099D9A6
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

414996:CDG81 RS11055
gene id: 414996:CDG81_RS11055
uniprot id: A0A099D5R1
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

414996:CDG81 RS16360
gene id: 414996:CDG81_RS16360
uniprot id: A0A099D548
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

414996:CDG81 RS06600
gene id: 414996:CDG81_RS06600
uniprot id: A0A223RQ89
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS17570
gene id: 414996:CDG81_RS17570
uniprot id: A0A099D102
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

414996:CDG81 RS09920
gene id: 414996:CDG81_RS09920
uniprot id: A0A099D7Z4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS05375
gene id: 414996:CDG81_RS05375
uniprot id: A0A099D2Q8
names: Similarity
messages: Belongs to the UPF0045 family.

414996:CDG81 RS19225
gene id: 414996:CDG81_RS19225
uniprot id: A0A099D8U3
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS22570
gene id: 414996:CDG81_RS22570
uniprot id: A0A099D9H5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

414996:CDG81 RS00220
gene id: 414996:CDG81_RS00220
uniprot id: A0A099DAE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS10300
gene id: 414996:CDG81_RS10300
uniprot id: A0A223RRY9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

414996:CDG81 RS20605
gene id: 414996:CDG81_RS20605
uniprot id: A0A099D920
names: Similarity
messages: Belongs to the WrbA family.

414996:CDG81 RS17350
gene id: 414996:CDG81_RS17350
uniprot id: A0A099D2L9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

414996:CDG81 RS16350
gene id: 414996:CDG81_RS16350
uniprot id: A0A099D4G5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

414996:CDG81 RS16175
gene id: 414996:CDG81_RS16175
uniprot id: A0A099D4Y3
names: Similarity
messages: Belongs to the arsA ATPase family.

414996:CDG81 RS07195
gene id: 414996:CDG81_RS07195
uniprot id: A0A099D680
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

414996:CDG81 RS18435
gene id: 414996:CDG81_RS18435
uniprot id: A0A099DAH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

414996:CDG81 RS19730
gene id: 414996:CDG81_RS19730
uniprot id: A0A099D934
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

414996:CDG81 RS16225
gene id: 414996:CDG81_RS16225
uniprot id: A0A099D6S9
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

414996:CDG81 RS09935
gene id: 414996:CDG81_RS09935
uniprot id: A0A099D7E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS20040
gene id: 414996:CDG81_RS20040
uniprot id: A0A099D9I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

414996:CDG81 RS16715
gene id: 414996:CDG81_RS16715
uniprot id: A0A099CZP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

414996:CDG81 RS17075
gene id: 414996:CDG81_RS17075
uniprot id: A0A223RUY3
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

414996:CDG81 RS20310
gene id: 414996:CDG81_RS20310
uniprot id: A0A099D9E1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

414996:CDG81 RS10500
gene id: 414996:CDG81_RS10500
uniprot id: A0A099D6C4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

414996:CDG81 RS04775
gene id: 414996:CDG81_RS04775
uniprot id: A0A099D165
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

414996:CDG81 RS05945
gene id: 414996:CDG81_RS05945
uniprot id: A0A099D126
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS11050
gene id: 414996:CDG81_RS11050
uniprot id: A0A223RS77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

414996:CDG81 RS01175
gene id: 414996:CDG81_RS01175
uniprot id: A0A099DCJ8
names: Similarity
messages: Belongs to the Dps family.

414996:CDG81 RS16150
gene id: 414996:CDG81_RS16150
uniprot id: A0A099D4I9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

414996:CDG81 RS01220
gene id: 414996:CDG81_RS01220
uniprot id: A0A099DAN3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS16665
gene id: 414996:CDG81_RS16665
uniprot id: A0A099D0V0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

414996:CDG81 RS14940
gene id: 414996:CDG81_RS14940
uniprot id: A0A099D4E5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

414996:CDG81 RS07440
gene id: 414996:CDG81_RS07440
uniprot id: A0A099D648
names: Similarity
messages: Belongs to the UPF0098 family.

414996:CDG81 RS09165
gene id: 414996:CDG81_RS09165
uniprot id: A0A223RRC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

414996:CDG81 RS14870
gene id: 414996:CDG81_RS14870
uniprot id: A0A099D452
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

414996:CDG81 RS04370
gene id: 414996:CDG81_RS04370
uniprot id: A0A099D420
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

414996:CDG81 RS19110
gene id: 414996:CDG81_RS19110
uniprot id: A0A223RZG9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

414996:CDG81 RS05585
gene id: 414996:CDG81_RS05585
uniprot id: A0A223RPR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

414996:CDG81 RS00980
gene id: 414996:CDG81_RS00980
uniprot id: A0A099DAQ6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

414996:CDG81 RS07345
gene id: 414996:CDG81_RS07345
uniprot id: A0A099D6J0
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS16095
gene id: 414996:CDG81_RS16095
uniprot id: A0A099D5J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

414996:CDG81 RS05815
gene id: 414996:CDG81_RS05815
uniprot id: A0A099D101
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

414996:CDG81 RS01470
gene id: 414996:CDG81_RS01470
uniprot id: A0A099DAB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

414996:CDG81 RS20490
gene id: 414996:CDG81_RS20490
uniprot id: A0A099DA60
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

414996:CDG81 RS19965
gene id: 414996:CDG81_RS19965
uniprot id: A0A099D993
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

414996:CDG81 RS19985
gene id: 414996:CDG81_RS19985
uniprot id: A0A099D9K0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

414996:CDG81 RS00015
gene id: 414996:CDG81_RS00015
uniprot id: A0A099D9V0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

414996:CDG81 RS16610
gene id: 414996:CDG81_RS16610
uniprot id: A0A099D0W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS06035
gene id: 414996:CDG81_RS06035
uniprot id: A0A099D2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

414996:CDG81 RS22580
gene id: 414996:CDG81_RS22580
uniprot id: A0A099DAB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS05860
gene id: 414996:CDG81_RS05860
uniprot id: A0A099D1G9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

414996:CDG81 RS04975
gene id: 414996:CDG81_RS04975
uniprot id: A0A099D1T7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

414996:CDG81 RS01615
gene id: 414996:CDG81_RS01615
uniprot id: A0A099DAA1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS10615
gene id: 414996:CDG81_RS10615
uniprot id: A0A099D660
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS00800
gene id: 414996:CDG81_RS00800
uniprot id: A0A099DBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

414996:CDG81 RS16130
gene id: 414996:CDG81_RS16130
uniprot id: A0A223RUH0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

414996:CDG81 RS18905
gene id: 414996:CDG81_RS18905
uniprot id: A0A099D901
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

414996:CDG81 RS00660
gene id: 414996:CDG81_RS00660
uniprot id: A0A099DAM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

414996:CDG81 RS04265
gene id: 414996:CDG81_RS04265
uniprot id: A0A099D5B7
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS05995
gene id: 414996:CDG81_RS05995
uniprot id: A0A099D1X0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

414996:CDG81 RS09465
gene id: 414996:CDG81_RS09465
uniprot id: A0A099D8I0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

414996:CDG81 RS14510
gene id: 414996:CDG81_RS14510
uniprot id: A0A099D3S5
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

414996:CDG81 RS09865
gene id: 414996:CDG81_RS09865
uniprot id: A0A099D8D4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

414996:CDG81 RS21585
gene id: 414996:CDG81_RS21585
uniprot id: A0A099D9Y9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

414996:CDG81 RS21810
gene id: 414996:CDG81_RS21810
uniprot id: A0A099DAR5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

414996:CDG81 RS06040
gene id: 414996:CDG81_RS06040
uniprot id: A0A099D170
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

414996:CDG81 RS00020
gene id: 414996:CDG81_RS00020
uniprot id: A0A099DB15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

414996:CDG81 RS14140
gene id: 414996:CDG81_RS14140
uniprot id: A0A099D5Y8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

414996:CDG81 RS02170
gene id: 414996:CDG81_RS02170
uniprot id: A0A099D4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

414996:CDG81 RS05140
gene id: 414996:CDG81_RS05140
uniprot id: A0A099D1I3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

414996:CDG81 RS14015
gene id: 414996:CDG81_RS14015
uniprot id: A0A099D4D3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS23070
gene id: 414996:CDG81_RS23070
uniprot id: A0A099D9W8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

414996:CDG81 RS14850
gene id: 414996:CDG81_RS14850
uniprot id: A0A099D3S1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

414996:CDG81 RS20470
gene id: 414996:CDG81_RS20470
uniprot id: A0A099D9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

414996:CDG81 RS22405
gene id: 414996:CDG81_RS22405
uniprot id: A0A099DA21
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS20870
gene id: 414996:CDG81_RS20870
uniprot id: A0A099D8Z6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

414996:CDG81 RS09845
gene id: 414996:CDG81_RS09845
uniprot id: A0A099D809
names: Similarity
messages: Belongs to the RutC family.

414996:CDG81 RS00160
gene id: 414996:CDG81_RS00160
uniprot id: A0A099DC83
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS23135
gene id: 414996:CDG81_RS23135
uniprot id: A0A099DAP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

414996:CDG81 RS21925
gene id: 414996:CDG81_RS21925
uniprot id: A0A099D9S5
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS15960
gene id: 414996:CDG81_RS15960
uniprot id: A0A099D4L1
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

414996:CDG81 RS21960
gene id: 414996:CDG81_RS21960
uniprot id: A0A099D9H4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS06270
gene id: 414996:CDG81_RS06270
uniprot id: A0A099D1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS05665
gene id: 414996:CDG81_RS05665
uniprot id: A0A099D0X1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

414996:CDG81 RS17280
gene id: 414996:CDG81_RS17280
uniprot id: A0A099D044
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

414996:CDG81 RS19900
gene id: 414996:CDG81_RS19900
uniprot id: A0A099D8Y1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

414996:CDG81 RS01095
gene id: 414996:CDG81_RS01095
uniprot id: A0A099DB91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS21200
gene id: 414996:CDG81_RS21200
uniprot id: A0A223RWY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

414996:CDG81 RS18985
gene id: 414996:CDG81_RS18985
uniprot id: A0A099D8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

414996:CDG81 RS20585
gene id: 414996:CDG81_RS20585
uniprot id: A0A099D9R5
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS08810
gene id: 414996:CDG81_RS08810
uniprot id: A0A099D714
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS07270
gene id: 414996:CDG81_RS07270
uniprot id: A0A223RQJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

414996:CDG81 RS03265
gene id: 414996:CDG81_RS03265
uniprot id: A0A223RNN1
names: Similarity
messages: Belongs to the IucA/IucC family.

414996:CDG81 RS05790
gene id: 414996:CDG81_RS05790
uniprot id: A0A099D0Z6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

414996:CDG81 RS04945
gene id: 414996:CDG81_RS04945
uniprot id: A0A099D3S8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

414996:CDG81 RS14630
gene id: 414996:CDG81_RS14630
uniprot id: A0A223RTY3
names: Similarity
messages: Belongs to the peptidase A31 family.

414996:CDG81 RS18815
gene id: 414996:CDG81_RS18815
uniprot id: A0A223RVT9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

414996:CDG81 RS08275
gene id: 414996:CDG81_RS08275
uniprot id: A0A099D6F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

414996:CDG81 RS14910
gene id: 414996:CDG81_RS14910
uniprot id: A0A099D4S4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

414996:CDG81 RS06155
gene id: 414996:CDG81_RS06155
uniprot id: A0A223RQ15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

414996:CDG81 RS15010
gene id: 414996:CDG81_RS15010
uniprot id: A0A099D5E7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS15850
gene id: 414996:CDG81_RS15850
uniprot id: A0A099D492
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

414996:CDG81 RS18800
gene id: 414996:CDG81_RS18800
uniprot id: A0A099D8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

414996:CDG81 RS13225
gene id: 414996:CDG81_RS13225
uniprot id: A0A099D456
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS00225
gene id: 414996:CDG81_RS00225
uniprot id: A0A099DA56
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS02575
gene id: 414996:CDG81_RS02575
uniprot id: A0A099D1R3
names: Similarity
messages: Belongs to the malic enzymes family.

414996:CDG81 RS15005
gene id: 414996:CDG81_RS15005
uniprot id: A0A099D4E9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

414996:CDG81 RS10230
gene id: 414996:CDG81_RS10230
uniprot id: A0A099D633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

414996:CDG81 RS22225
gene id: 414996:CDG81_RS22225
uniprot id: A0A099DAI5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

414996:CDG81 RS21740
gene id: 414996:CDG81_RS21740
uniprot id: A0A223RXI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

414996:CDG81 RS12525
gene id: 414996:CDG81_RS12525
uniprot id: A0A223RT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

414996:CDG81 RS02630
gene id: 414996:CDG81_RS02630
uniprot id: A0A223RND9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

414996:CDG81 RS06975
gene id: 414996:CDG81_RS06975
uniprot id: A0A223RQF6
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.

414996:CDG81 RS04550
gene id: 414996:CDG81_RS04550
uniprot id: A0A099D449
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS06875
gene id: 414996:CDG81_RS06875
uniprot id: A0A099D6Q7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

414996:CDG81 RS10640
gene id: 414996:CDG81_RS10640
uniprot id: A0A099D7P5
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS17020
gene id: 414996:CDG81_RS17020
uniprot id: A0A223RUZ2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

414996:CDG81 RS02580
gene id: 414996:CDG81_RS02580
uniprot id: A0A099D2W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

414996:CDG81 RS06470
gene id: 414996:CDG81_RS06470
uniprot id: A0A099D1S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

414996:CDG81 RS19345
gene id: 414996:CDG81_RS19345
uniprot id: A0A099D8F4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

414996:CDG81 RS07910
gene id: 414996:CDG81_RS07910
uniprot id: A0A099D8S8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

414996:CDG81 RS10745
gene id: 414996:CDG81_RS10745
uniprot id: A0A099D7R2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

414996:CDG81 RS11650
gene id: 414996:CDG81_RS11650
uniprot id: A0A099D7G1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

414996:CDG81 RS05130
gene id: 414996:CDG81_RS05130
uniprot id: A0A099D286
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

414996:CDG81 RS19715
gene id: 414996:CDG81_RS19715
uniprot id: A0A099D9U8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

414996:CDG81 RS21745
gene id: 414996:CDG81_RS21745
uniprot id: A0A099DBT4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

414996:CDG81 RS14670
gene id: 414996:CDG81_RS14670
uniprot id: A0A099D3Q4
names: Similarity
messages: Belongs to the HupF/HypC family.

414996:CDG81 RS17345
gene id: 414996:CDG81_RS17345
uniprot id: A0A099D0V5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

414996:CDG81 RS09310
gene id: 414996:CDG81_RS09310
uniprot id: A0A099D872
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

414996:CDG81 RS01855
gene id: 414996:CDG81_RS01855
uniprot id: A0A099D216
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

414996:CDG81 RS22020
gene id: 414996:CDG81_RS22020
uniprot id: A0A099DAM5
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

414996:CDG81 RS20555
gene id: 414996:CDG81_RS20555
uniprot id: A0A099D9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

414996:CDG81 RS09870
gene id: 414996:CDG81_RS09870
uniprot id: A0A099D804
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

414996:CDG81 RS22765
gene id: 414996:CDG81_RS22765
uniprot id: A0A099D961
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

414996:CDG81 RS12515
gene id: 414996:CDG81_RS12515
uniprot id: A0A099D5U3
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS07005
gene id: 414996:CDG81_RS07005
uniprot id: A0A099D6A4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS19430
gene id: 414996:CDG81_RS19430
uniprot id: A0A223RW18
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

414996:CDG81 RS02890
gene id: 414996:CDG81_RS02890
uniprot id: A0A099D342
names: Similarity
messages: Belongs to the citrate synthase family.

414996:CDG81 RS19545
gene id: 414996:CDG81_RS19545
uniprot id: A0A099D7Q3
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

414996:CDG81 RS01090
gene id: 414996:CDG81_RS01090
uniprot id: A0A099DBL2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

414996:CDG81 RS19805
gene id: 414996:CDG81_RS19805
uniprot id: A0A099D9D3
names: Similarity
messages: Belongs to the EccD/Snm4 family.

414996:CDG81 RS02505
gene id: 414996:CDG81_RS02505
uniprot id: A0A099D2H3
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

414996:CDG81 RS01405
gene id: 414996:CDG81_RS01405
uniprot id: A0A099DAL1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

414996:CDG81 RS22730
gene id: 414996:CDG81_RS22730
uniprot id: A0A223RZU6
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS21235
gene id: 414996:CDG81_RS21235
uniprot id: A0A099DB25
names: Similarity
messages: Belongs to the IMPACT family.

414996:CDG81 RS13275
gene id: 414996:CDG81_RS13275
uniprot id: A0A099D5F9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS16305
gene id: 414996:CDG81_RS16305
uniprot id: A0A099D554
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

414996:CDG81 RS07140
gene id: 414996:CDG81_RS07140
uniprot id: A0A099D6M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS08950
gene id: 414996:CDG81_RS08950
uniprot id: A0A099D7W0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS09810
gene id: 414996:CDG81_RS09810
uniprot id: A0A099D7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS01125
gene id: 414996:CDG81_RS01125
uniprot id: A0A223RMQ0
names: Similarity
messages: Belongs to the Fur family.

414996:CDG81 RS07120
gene id: 414996:CDG81_RS07120
uniprot id: A0A223RQH0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

414996:CDG81 RS17625
gene id: 414996:CDG81_RS17625
uniprot id: A0A099D0Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

414996:CDG81 RS14130
gene id: 414996:CDG81_RS14130
uniprot id: A0A099D4N5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

414996:CDG81 RS07190
gene id: 414996:CDG81_RS07190
uniprot id: A0A099D6L4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

414996:CDG81 RS11015
gene id: 414996:CDG81_RS11015
uniprot id: A0A099D643
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS09475
gene id: 414996:CDG81_RS09475
uniprot id: A0A223RRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

414996:CDG81 RS04260
gene id: 414996:CDG81_RS04260
uniprot id: A0A099D3P6
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

414996:CDG81 RS07780
gene id: 414996:CDG81_RS07780
uniprot id: A0A099D8V6
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS11520
gene id: 414996:CDG81_RS11520
uniprot id: A0A099D657
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

414996:CDG81 RS12770
gene id: 414996:CDG81_RS12770
uniprot id: A0A099D6Z9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

414996:CDG81 RS09440
gene id: 414996:CDG81_RS09440
uniprot id: A0A099D850
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

414996:CDG81 RS06290
gene id: 414996:CDG81_RS06290
uniprot id: A0A099D1C1
names: Similarity
messages: Belongs to the serpin family.

414996:CDG81 RS00030
gene id: 414996:CDG81_RS00030
uniprot id: A0A099DC25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

414996:CDG81 RS11330
gene id: 414996:CDG81_RS11330
uniprot id: A0A099D6B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

414996:CDG81 RS04845
gene id: 414996:CDG81_RS04845
uniprot id: A0A099D213
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

414996:CDG81 RS07840
gene id: 414996:CDG81_RS07840
uniprot id: A0A099D732
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS00615
gene id: 414996:CDG81_RS00615
uniprot id: A0A099DBS1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

414996:CDG81 RS20880
gene id: 414996:CDG81_RS20880
uniprot id: A0A099D9M9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

414996:CDG81 RS12235
gene id: 414996:CDG81_RS12235
uniprot id: A0A099D799
names: Similarity
messages: Belongs to the universal stress protein A family.

414996:CDG81 RS20435
gene id: 414996:CDG81_RS20435
uniprot id: A0A223RWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

414996:CDG81 RS02615
gene id: 414996:CDG81_RS02615
uniprot id: A0A099D468
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

414996:CDG81 RS19115
gene id: 414996:CDG81_RS19115
uniprot id: A0A099DA47
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

414996:CDG81 RS20455
gene id: 414996:CDG81_RS20455
uniprot id: A0A223RWW8
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

414996:CDG81 RS23060
gene id: 414996:CDG81_RS23060
uniprot id: A0A099DC49
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS14215
gene id: 414996:CDG81_RS14215
uniprot id: A0A099D4A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

414996:CDG81 RS13220
gene id: 414996:CDG81_RS13220
uniprot id: A0A099D341
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

414996:CDG81 RS05460
gene id: 414996:CDG81_RS05460
uniprot id: A0A099D199
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS21445
gene id: 414996:CDG81_RS21445
uniprot id: A0A223RWY9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

414996:CDG81 RS04985
gene id: 414996:CDG81_RS04985
uniprot id: A0A099D242
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

414996:CDG81 RS12875
gene id: 414996:CDG81_RS12875
uniprot id: A0A099D716
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

414996:CDG81 RS21860
gene id: 414996:CDG81_RS21860
uniprot id: A0A099DAB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

414996:CDG81 RS14190
gene id: 414996:CDG81_RS14190
uniprot id: A0A099D5X7
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

414996:CDG81 RS06840
gene id: 414996:CDG81_RS06840
uniprot id: A0A223RQB7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

414996:CDG81 RS15975
gene id: 414996:CDG81_RS15975
uniprot id: A0A223RUG3
names: Similarity
messages: Belongs to the peptidase S15 family.

414996:CDG81 RS08070
gene id: 414996:CDG81_RS08070
uniprot id: A0A099D8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

414996:CDG81 RS20465
gene id: 414996:CDG81_RS20465
uniprot id: A0A099DA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

414996:CDG81 RS20540
gene id: 414996:CDG81_RS20540
uniprot id: A0A099D9C4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

414996:CDG81 RS08295
gene id: 414996:CDG81_RS08295
uniprot id: A0A099D8K8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

414996:CDG81 RS18490
gene id: 414996:CDG81_RS18490
uniprot id: A0A099D8W0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

414996:CDG81 RS11720
gene id: 414996:CDG81_RS11720
uniprot id: A0A099D5Y5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

414996:CDG81 RS00115
gene id: 414996:CDG81_RS00115
uniprot id: A0A099DA33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

414996:CDG81 RS15495
gene id: 414996:CDG81_RS15495
uniprot id: A0A099D4H0
names: Cofactor
messages: Binds 1 FAD per subunit.

414996:CDG81 RS19680
gene id: 414996:CDG81_RS19680
uniprot id: A0A099D9V2
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

414996:CDG81 RS14065
gene id: 414996:CDG81_RS14065
uniprot id: A0A099D3N1
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS06280
gene id: 414996:CDG81_RS06280
uniprot id: A0A099D115
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

414996:CDG81 RS07915
gene id: 414996:CDG81_RS07915
uniprot id: A0A099D713
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

414996:CDG81 RS08395
gene id: 414996:CDG81_RS08395
uniprot id: A0A099D7P6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

414996:CDG81 RS08200
gene id: 414996:CDG81_RS08200
uniprot id: A0A099D753
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

414996:CDG81 RS00495
gene id: 414996:CDG81_RS00495
uniprot id: A0A099DAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

414996:CDG81 RS16635
gene id: 414996:CDG81_RS16635
uniprot id: A0A099CZR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

414996:CDG81 RS11665
gene id: 414996:CDG81_RS11665
uniprot id: A0A223RSL4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS12185
gene id: 414996:CDG81_RS12185
uniprot id: A0A099D4Z0
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS22505
gene id: 414996:CDG81_RS22505
uniprot id: A0A099DBF7
names: Similarity
messages: Belongs to the asp23 family.

414996:CDG81 RS18620
gene id: 414996:CDG81_RS18620
uniprot id: A0A099D848
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

414996:CDG81 RS21850
gene id: 414996:CDG81_RS21850
uniprot id: A0A099D9J2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

414996:CDG81 RS11275
gene id: 414996:CDG81_RS11275
uniprot id: A0A099D6J6
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

414996:CDG81 RS17235
gene id: 414996:CDG81_RS17235
uniprot id: A0A099D191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

414996:CDG81 RS04555
gene id: 414996:CDG81_RS04555
uniprot id: A0A099D2E5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

414996:CDG81 RS02830
gene id: 414996:CDG81_RS02830
uniprot id: A0A099D3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

414996:CDG81 RS20430
gene id: 414996:CDG81_RS20430
uniprot id: A0A099D940
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

414996:CDG81 RS01610
gene id: 414996:CDG81_RS01610
uniprot id: A0A099DAI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS02530
gene id: 414996:CDG81_RS02530
uniprot id: A0A099D2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS12685
gene id: 414996:CDG81_RS12685
uniprot id: A0A223RT21
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS15525
gene id: 414996:CDG81_RS15525
uniprot id: A0A099D409
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

414996:CDG81 RS22315
gene id: 414996:CDG81_RS22315
uniprot id: A0A099DA36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS08140
gene id: 414996:CDG81_RS08140
uniprot id: A0A099D7G2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS14280
gene id: 414996:CDG81_RS14280
uniprot id: A0A099D3J4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

414996:CDG81 RS20025
gene id: 414996:CDG81_RS20025
uniprot id: A0A099DAT0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS09480
gene id: 414996:CDG81_RS09480
uniprot id: A0A099D9Q5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

414996:CDG81 RS07575
gene id: 414996:CDG81_RS07575
uniprot id: A0A099D6T6
names: Similarity
messages: Belongs to the UPF0047 family.

414996:CDG81 RS14620
gene id: 414996:CDG81_RS14620
uniprot id: A0A099D5R0
names: Similarity
messages: Belongs to the HypD family.

414996:CDG81 RS16330
gene id: 414996:CDG81_RS16330
uniprot id: A0A099D550
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS04880
gene id: 414996:CDG81_RS04880
uniprot id: A0A099D2F0
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

414996:CDG81 RS06620
gene id: 414996:CDG81_RS06620
uniprot id: A0A223RQE1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

414996:CDG81 RS14490
gene id: 414996:CDG81_RS14490
uniprot id: A0A099D3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

414996:CDG81 RS11375
gene id: 414996:CDG81_RS11375
uniprot id: A0A099D5Y9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

414996:CDG81 RS20820
gene id: 414996:CDG81_RS20820
uniprot id: A0A099DB66
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS22215
gene id: 414996:CDG81_RS22215
uniprot id: A0A099D9M6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

414996:CDG81 RS01370
gene id: 414996:CDG81_RS01370
uniprot id: A0A223RMU8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

414996:CDG81 RS01435
gene id: 414996:CDG81_RS01435
uniprot id: A0A223RMV8
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS22240
gene id: 414996:CDG81_RS22240
uniprot id: A0A099DBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS04855
gene id: 414996:CDG81_RS04855
uniprot id: A0A099D2E3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

414996:CDG81 RS08695
gene id: 414996:CDG81_RS08695
uniprot id: A0A099D741
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

414996:CDG81 RS00680
gene id: 414996:CDG81_RS00680
uniprot id: A0A099DCQ4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS14495
gene id: 414996:CDG81_RS14495
uniprot id: A0A099D4G9
names: Similarity
messages: Belongs to the GPI family.

414996:CDG81 RS14695
gene id: 414996:CDG81_RS14695
uniprot id: A0A099D3P8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

414996:CDG81 RS00245
gene id: 414996:CDG81_RS00245
uniprot id: A0A099DAE4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS07710
gene id: 414996:CDG81_RS07710
uniprot id: A0A099D6Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

414996:CDG81 RS21330
gene id: 414996:CDG81_RS21330
uniprot id: A0A099D9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

414996:CDG81 RS05870
gene id: 414996:CDG81_RS05870
uniprot id: A0A099D3I3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

414996:CDG81 RS14155
gene id: 414996:CDG81_RS14155
uniprot id: A0A099D4N0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

414996:CDG81 RS15405
gene id: 414996:CDG81_RS15405
uniprot id: A0A099D4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

414996:CDG81 RS07525
gene id: 414996:CDG81_RS07525
uniprot id: A0A099D6V1
names: Similarity
messages: Belongs to the CobH/CbiC family.

414996:CDG81 RS19570
gene id: 414996:CDG81_RS19570
uniprot id: A0A099D7Q0
names: Similarity
messages: Belongs to the UPF0045 family.

414996:CDG81 RS11150
gene id: 414996:CDG81_RS11150
uniprot id: A0A223RSB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

414996:CDG81 RS06200
gene id: 414996:CDG81_RS06200
uniprot id: A0A099D317
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

414996:CDG81 RS11135
gene id: 414996:CDG81_RS11135
uniprot id: A0A099D667
names: Similarity
messages: Belongs to the universal stress protein A family.

414996:CDG81 RS05275
gene id: 414996:CDG81_RS05275
uniprot id: A0A099D401
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

414996:CDG81 RS22175
gene id: 414996:CDG81_RS22175
uniprot id: A0A099DBK6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

414996:CDG81 RS09380
gene id: 414996:CDG81_RS09380
uniprot id: A0A099D8J2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

414996:CDG81 RS15945
gene id: 414996:CDG81_RS15945
uniprot id: A0A099D595
names: Similarity
messages: Belongs to the histone deacetylase family.

414996:CDG81 RS07060
gene id: 414996:CDG81_RS07060
uniprot id: A0A099D785
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

414996:CDG81 RS20000
gene id: 414996:CDG81_RS20000
uniprot id: A0A099D8V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

414996:CDG81 RS06865
gene id: 414996:CDG81_RS06865
uniprot id: A0A099D8I6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS08185
gene id: 414996:CDG81_RS08185
uniprot id: A0A099D6V4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

414996:CDG81 RS05605
gene id: 414996:CDG81_RS05605
uniprot id: A0A099D3D5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

414996:CDG81 RS09385
gene id: 414996:CDG81_RS09385
uniprot id: A0A223RRF6
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

414996:CDG81 RS12060
gene id: 414996:CDG81_RS12060
uniprot id: A0A099D5B9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

414996:CDG81 RS15280
gene id: 414996:CDG81_RS15280
uniprot id: A0A099D466
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

414996:CDG81 RS10010
gene id: 414996:CDG81_RS10010
uniprot id: A0A099D607
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

414996:CDG81 RS06205
gene id: 414996:CDG81_RS06205
uniprot id: A0A099D1A4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS19535
gene id: 414996:CDG81_RS19535
uniprot id: A0A223RW42
names: Similarity
messages: Belongs to the allantoicase family.

414996:CDG81 RS10540
gene id: 414996:CDG81_RS10540
uniprot id: A0A099D5E2
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

414996:CDG81 RS07125
gene id: 414996:CDG81_RS07125
uniprot id: A0A099D6W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

414996:CDG81 RS02620
gene id: 414996:CDG81_RS02620
uniprot id: A0A099D253
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

414996:CDG81 RS02210
gene id: 414996:CDG81_RS02210
uniprot id: A0A099D309
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

414996:CDG81 RS04795
gene id: 414996:CDG81_RS04795
uniprot id: A0A099D2D0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS10470
gene id: 414996:CDG81_RS10470
uniprot id: A0A223RRX9
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

414996:CDG81 RS14610
gene id: 414996:CDG81_RS14610
uniprot id: A0A099D4F1
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

414996:CDG81 RS10160
gene id: 414996:CDG81_RS10160
uniprot id: A0A099D6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

414996:CDG81 RS17205
gene id: 414996:CDG81_RS17205
uniprot id: A0A099D0X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

414996:CDG81 RS07335
gene id: 414996:CDG81_RS07335
uniprot id: A0A223RQK7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

414996:CDG81 RS05750
gene id: 414996:CDG81_RS05750
uniprot id: A0A099D0Z0
names: Similarity
messages: Belongs to the ComB family.

414996:CDG81 RS12845
gene id: 414996:CDG81_RS12845
uniprot id: A0A223RT29
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

414996:CDG81 RS08420
gene id: 414996:CDG81_RS08420
uniprot id: A0A099D7M6
names: Similarity
messages: Belongs to the OsmC/Ohr family.

414996:CDG81 RS02840
gene id: 414996:CDG81_RS02840
uniprot id: A0A099D4V1
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS19920
gene id: 414996:CDG81_RS19920
uniprot id: A0A099DAV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

414996:CDG81 RS22125
gene id: 414996:CDG81_RS22125
uniprot id: A0A099D9P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

414996:CDG81 RS03650
gene id: 414996:CDG81_RS03650
uniprot id: A0A099D2P7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

414996:CDG81 RS15760
gene id: 414996:CDG81_RS15760
uniprot id: A0A099D683
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS01315
gene id: 414996:CDG81_RS01315
uniprot id: A0A099DAD1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

414996:CDG81 RS14835
gene id: 414996:CDG81_RS14835
uniprot id: A0A099D4G6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

414996:CDG81 RS04780
gene id: 414996:CDG81_RS04780
uniprot id: A0A223RPE6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

414996:CDG81 RS16075
gene id: 414996:CDG81_RS16075
uniprot id: A0A099D581
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

414996:CDG81 RS19865
gene id: 414996:CDG81_RS19865
uniprot id: A0A099D9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

414996:CDG81 RS00705
gene id: 414996:CDG81_RS00705
uniprot id: A0A099DCP9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

414996:CDG81 RS12440
gene id: 414996:CDG81_RS12440
uniprot id: A0A099D5H6
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

414996:CDG81 RS16530
gene id: 414996:CDG81_RS16530
uniprot id: A0A099D0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

414996:CDG81 RS21305
gene id: 414996:CDG81_RS21305
uniprot id: A0A099D9W3
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS17495
gene id: 414996:CDG81_RS17495
uniprot id: A0A099D0T9
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS01035
gene id: 414996:CDG81_RS01035
uniprot id: A0A099DBL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS20100
gene id: 414996:CDG81_RS20100
uniprot id: A0A099D8I8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

414996:CDG81 RS01735
gene id: 414996:CDG81_RS01735
uniprot id: A0A099D2T5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

414996:CDG81 RS03585
gene id: 414996:CDG81_RS03585
uniprot id: A0A099D556
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

414996:CDG81 RS09035
gene id: 414996:CDG81_RS09035
uniprot id: A0A099D7B0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS14565
gene id: 414996:CDG81_RS14565
uniprot id: A0A099D3E1
names: Similarity
messages: Belongs to the EspG family.

414996:CDG81 RS06180
gene id: 414996:CDG81_RS06180
uniprot id: A0A099D198
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

414996:CDG81 RS03660
gene id: 414996:CDG81_RS03660
uniprot id: A0A099D3E7
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS10200
gene id: 414996:CDG81_RS10200
uniprot id: A0A223RRX3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

414996:CDG81 RS16270
gene id: 414996:CDG81_RS16270
uniprot id: A0A099D4H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

414996:CDG81 RS08730
gene id: 414996:CDG81_RS08730
uniprot id: A0A099D806
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

414996:CDG81 RS16485
gene id: 414996:CDG81_RS16485
uniprot id: A0A099D2F9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS01020
gene id: 414996:CDG81_RS01020
uniprot id: A0A099DCL5
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

414996:CDG81 RS22640
gene id: 414996:CDG81_RS22640
uniprot id: A0A099D9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

414996:CDG81 RS18580
gene id: 414996:CDG81_RS18580
uniprot id: A0A099D8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS05475
gene id: 414996:CDG81_RS05475
uniprot id: A0A099D1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

414996:CDG81 RS06420
gene id: 414996:CDG81_RS06420
uniprot id: A0A099D0L2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

414996:CDG81 RS19855
gene id: 414996:CDG81_RS19855
uniprot id: A0A099D9P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

414996:CDG81 RS20525
gene id: 414996:CDG81_RS20525
uniprot id: A0A099DA55
names: Similarity
messages: Belongs to the peptidase M1 family.

414996:CDG81 RS19310
gene id: 414996:CDG81_RS19310
uniprot id: A0A099D7T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

414996:CDG81 RS06090
gene id: 414996:CDG81_RS06090
uniprot id: A0A099D0Y6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

414996:CDG81 RS03755
gene id: 414996:CDG81_RS03755
uniprot id: A0A099D312
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

414996:CDG81 RS12195
gene id: 414996:CDG81_RS12195
uniprot id: A0A099D794
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS19930
gene id: 414996:CDG81_RS19930
uniprot id: A0A099D8M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

414996:CDG81 RS11160
gene id: 414996:CDG81_RS11160
uniprot id: A0A099D5T6
names: Similarity
messages: Belongs to the universal stress protein A family.

414996:CDG81 RS15610
gene id: 414996:CDG81_RS15610
uniprot id: A0A099D3Z2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS21180
gene id: 414996:CDG81_RS21180
uniprot id: A0A099D963
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS07470
gene id: 414996:CDG81_RS07470
uniprot id: A0A099D644
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

414996:CDG81 RS15815
gene id: 414996:CDG81_RS15815
uniprot id: A0A099D4K2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

414996:CDG81 RS03455
gene id: 414996:CDG81_RS03455
uniprot id: A0A099D582
names: Similarity
messages: Belongs to the UDPGP type 2 family.

414996:CDG81 RS15290
gene id: 414996:CDG81_RS15290
uniprot id: A0A099D4V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

414996:CDG81 RS05930
gene id: 414996:CDG81_RS05930
uniprot id: A0A099D3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

414996:CDG81 RS06185
gene id: 414996:CDG81_RS06185
uniprot id: A0A099D1N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

414996:CDG81 RS19970
gene id: 414996:CDG81_RS19970
uniprot id: A0A099DAU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

414996:CDG81 RS12505
gene id: 414996:CDG81_RS12505
uniprot id: A0A223RSZ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS09805
gene id: 414996:CDG81_RS09805
uniprot id: A0A223RRN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

414996:CDG81 RS04515
gene id: 414996:CDG81_RS04515
uniprot id: A0A099D1N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

414996:CDG81 RS22895
gene id: 414996:CDG81_RS22895
uniprot id: A0A099DA27
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

414996:CDG81 RS18900
gene id: 414996:CDG81_RS18900
uniprot id: A0A099D7Z7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

414996:CDG81 RS03885
gene id: 414996:CDG81_RS03885
uniprot id: A0A099D3A4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS18165
gene id: 414996:CDG81_RS18165
uniprot id: A0A099D109
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

414996:CDG81 RS17640
gene id: 414996:CDG81_RS17640
uniprot id: A0A099D0Q5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

414996:CDG81 RS19780
gene id: 414996:CDG81_RS19780
uniprot id: A0A099DAX4
names: Similarity
messages: Belongs to the WXG100 family.

414996:CDG81 RS19590
gene id: 414996:CDG81_RS19590
uniprot id: A0A099D808
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

414996:CDG81 RS01060
gene id: 414996:CDG81_RS01060
uniprot id: A0A223RMV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

414996:CDG81 RS03990
gene id: 414996:CDG81_RS03990
uniprot id: A0A099D3T0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

414996:CDG81 RS12205
gene id: 414996:CDG81_RS12205
uniprot id: A0A099D5P5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

414996:CDG81 RS18550
gene id: 414996:CDG81_RS18550
uniprot id: A0A099DAF3
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

414996:CDG81 RS13160
gene id: 414996:CDG81_RS13160
uniprot id: A0A099D746
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

414996:CDG81 RS16690
gene id: 414996:CDG81_RS16690
uniprot id: A0A099D0U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

414996:CDG81 RS15320
gene id: 414996:CDG81_RS15320
uniprot id: A0A099D6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

414996:CDG81 RS23100
gene id: 414996:CDG81_RS23100
uniprot id: A0A099DB30
names: Similarity
messages: Belongs to the ParB family.

414996:CDG81 RS08760
gene id: 414996:CDG81_RS08760
uniprot id: A0A223RR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

414996:CDG81 RS04365
gene id: 414996:CDG81_RS04365
uniprot id: A0A099D220
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

414996:CDG81 RS02760
gene id: 414996:CDG81_RS02760
uniprot id: A0A099D4W8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

414996:CDG81 RS08060
gene id: 414996:CDG81_RS08060
uniprot id: A0A099D7H7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

414996:CDG81 RS04910
gene id: 414996:CDG81_RS04910
uniprot id: A0A099D1A6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

414996:CDG81 RS17480
gene id: 414996:CDG81_RS17480
uniprot id: A0A223RV92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS10885
gene id: 414996:CDG81_RS10885
uniprot id: A0A099D618
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS15220
gene id: 414996:CDG81_RS15220
uniprot id: A0A223RU54
names: Similarity
messages: Belongs to the group II decarboxylase family.

414996:CDG81 RS15050
gene id: 414996:CDG81_RS15050
uniprot id: A0A099D5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

414996:CDG81 RS09470
gene id: 414996:CDG81_RS09470
uniprot id: A0A099D846
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS10270
gene id: 414996:CDG81_RS10270
uniprot id: A0A099D897
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

414996:CDG81 RS10930
gene id: 414996:CDG81_RS10930
uniprot id: A0A099D6B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

414996:CDG81 RS09910
gene id: 414996:CDG81_RS09910
uniprot id: A0A099D8C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

414996:CDG81 RS19475
gene id: 414996:CDG81_RS19475
uniprot id: A0A099D7R1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

414996:CDG81 RS06065
gene id: 414996:CDG81_RS06065
uniprot id: A0A223RQ63
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS01780
gene id: 414996:CDG81_RS01780
uniprot id: A0A099D2G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

414996:CDG81 RS03270
gene id: 414996:CDG81_RS03270
uniprot id: A0A223RNL9
names: Similarity
messages: Belongs to the IucA/IucC family.

414996:CDG81 RS04305
gene id: 414996:CDG81_RS04305
uniprot id: A0A099D3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

414996:CDG81 RS04005
gene id: 414996:CDG81_RS04005
uniprot id: A0A223RPC7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS15640
gene id: 414996:CDG81_RS15640
uniprot id: A0A099D3Y8
names: Similarity
messages: Belongs to the peptidase C56 family.

414996:CDG81 RS19850
gene id: 414996:CDG81_RS19850
uniprot id: A0A099D8P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

414996:CDG81 RS08660
gene id: 414996:CDG81_RS08660
uniprot id: A0A223RR57
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

414996:CDG81 RS02200
gene id: 414996:CDG81_RS02200
uniprot id: A0A099D2A0
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

414996:CDG81 RS06045
gene id: 414996:CDG81_RS06045
uniprot id: A0A099D1K7
names: Cofactor
messages: Can also use Mn(2+) ion.

414996:CDG81 RS19895
gene id: 414996:CDG81_RS19895
uniprot id: A0A099DAV6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

414996:CDG81 RS16060
gene id: 414996:CDG81_RS16060
uniprot id: A0A099D4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS21405
gene id: 414996:CDG81_RS21405
uniprot id: A0A099DA17
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS03540
gene id: 414996:CDG81_RS03540
uniprot id: A0A099D3U5
names: Similarity
messages: Belongs to the neutral ceramidase family.

414996:CDG81 RS19845
gene id: 414996:CDG81_RS19845
uniprot id: A0A099D8Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

414996:CDG81 RS16430
gene id: 414996:CDG81_RS16430
uniprot id: A0A099D4V4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

414996:CDG81 RS11515
gene id: 414996:CDG81_RS11515
uniprot id: A0A099D5V0
names: Similarity
messages: Belongs to the AHA1 family.

414996:CDG81 RS17855
gene id: 414996:CDG81_RS17855
uniprot id: A0A099D2W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS22980
gene id: 414996:CDG81_RS22980
uniprot id: A0A099D9Y7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

414996:CDG81 RS11145
gene id: 414996:CDG81_RS11145
uniprot id: A0A099D6F9
names: Similarity
messages: Belongs to the universal stress protein A family.

414996:CDG81 RS19875
gene id: 414996:CDG81_RS19875
uniprot id: A0A099D8Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

414996:CDG81 RS03140
gene id: 414996:CDG81_RS03140
uniprot id: A0A099D2L8
names: Similarity
messages: Belongs to the arginase family.

414996:CDG81 RS05950
gene id: 414996:CDG81_RS05950
uniprot id: A0A099D1I8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

414996:CDG81 RS07500
gene id: 414996:CDG81_RS07500
uniprot id: A0A099D6H3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS05760
gene id: 414996:CDG81_RS05760
uniprot id: A0A099D3G4
names: Similarity
messages: Belongs to the FPG family.

414996:CDG81 RS08775
gene id: 414996:CDG81_RS08775
uniprot id: A0A099D983
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

414996:CDG81 RS15275
gene id: 414996:CDG81_RS15275
uniprot id: A0A099D4M7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

414996:CDG81 RS19505
gene id: 414996:CDG81_RS19505
uniprot id: A0A223RW26
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

414996:CDG81 RS21380
gene id: 414996:CDG81_RS21380
uniprot id: A0A223RWZ8
names: Similarity
messages: Belongs to the PrpF family.

414996:CDG81 RS17510
gene id: 414996:CDG81_RS17510
uniprot id: A0A099D015
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

414996:CDG81 RS07100
gene id: 414996:CDG81_RS07100
uniprot id: A0A099D8F0
names: Similarity
messages: Belongs to the asparagine synthetase family.

414996:CDG81 RS06445
gene id: 414996:CDG81_RS06445
uniprot id: A0A099D0L8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

414996:CDG81 RS08000
gene id: 414996:CDG81_RS08000
uniprot id: A0A099D6Z6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

414996:CDG81 RS17780
gene id: 414996:CDG81_RS17780
uniprot id: A0A099D0D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

414996:CDG81 RS20005
gene id: 414996:CDG81_RS20005
uniprot id: A0A099D8L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

414996:CDG81 RS17945
gene id: 414996:CDG81_RS17945
uniprot id: A0A099D2V3
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS02325
gene id: 414996:CDG81_RS02325
uniprot id: A0A223RN97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

414996:CDG81 RS10365
gene id: 414996:CDG81_RS10365
uniprot id: A0A099D5S5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

414996:CDG81 RS17685
gene id: 414996:CDG81_RS17685
uniprot id: A0A223RV87
names: Similarity
messages: Belongs to the band 7/mec-2 family.

414996:CDG81 RS08030
gene id: 414996:CDG81_RS08030
uniprot id: A0A099D6J2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

414996:CDG81 RS17200
gene id: 414996:CDG81_RS17200
uniprot id: A0A099D195
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

414996:CDG81 RS12555
gene id: 414996:CDG81_RS12555
uniprot id: A0A099D5M3
names: Similarity
messages: Belongs to the CsoR family.

414996:CDG81 RS07530
gene id: 414996:CDG81_RS07530
uniprot id: A0A099D7T8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

414996:CDG81 RS07095
gene id: 414996:CDG81_RS07095
uniprot id: A0A099D6X2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

414996:CDG81 RS16825
gene id: 414996:CDG81_RS16825
uniprot id: A0A099CZL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

414996:CDG81 RS20650
gene id: 414996:CDG81_RS20650
uniprot id: A0A099DA38
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS03800
gene id: 414996:CDG81_RS03800
uniprot id: A0A099D3B9
names: Similarity
messages: Belongs to the EspG family.

414996:CDG81 RS04535
gene id: 414996:CDG81_RS04535
uniprot id: A0A099D2T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

414996:CDG81 RS20640
gene id: 414996:CDG81_RS20640
uniprot id: A0A223RX00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

414996:CDG81 RS06605
gene id: 414996:CDG81_RS06605
uniprot id: A0A099D381
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

414996:CDG81 RS21865
gene id: 414996:CDG81_RS21865
uniprot id: A0A099DBR3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

414996:CDG81 RS14010
gene id: 414996:CDG81_RS14010
uniprot id: A0A099D4Q4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS05435
gene id: 414996:CDG81_RS05435
uniprot id: A0A099D3B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

414996:CDG81 RS20380
gene id: 414996:CDG81_RS20380
uniprot id: A0A099D9D1
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

414996:CDG81 RS07160
gene id: 414996:CDG81_RS07160
uniprot id: A0A099D8E2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

414996:CDG81 RS05125
gene id: 414996:CDG81_RS05125
uniprot id: A0A099D3X6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS22145
gene id: 414996:CDG81_RS22145
uniprot id: A0A099DA66
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

414996:CDG81 RS00960
gene id: 414996:CDG81_RS00960
uniprot id: A0A099DAI1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

414996:CDG81 RS03805
gene id: 414996:CDG81_RS03805
uniprot id: A0A099D514
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

414996:CDG81 RS11025
gene id: 414996:CDG81_RS11025
uniprot id: A0A099D6D3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

414996:CDG81 RS05165
gene id: 414996:CDG81_RS05165
uniprot id: A0A099D1I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

414996:CDG81 RS18125
gene id: 414996:CDG81_RS18125
uniprot id: A0A099D1E1
names: Similarity
messages: Belongs to the FGGY kinase family.

414996:CDG81 RS23020
gene id: 414996:CDG81_RS23020
uniprot id: A0A099DB51
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

414996:CDG81 RS06540
gene id: 414996:CDG81_RS06540
uniprot id: A0A099D371
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

414996:CDG81 RS21685
gene id: 414996:CDG81_RS21685
uniprot id: A0A099DAF1
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

414996:CDG81 RS06765
gene id: 414996:CDG81_RS06765
uniprot id: A0A099D8J9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS17675
gene id: 414996:CDG81_RS17675
uniprot id: A0A223RVC0
names: Similarity
messages: Belongs to the LOG family.

414996:CDG81 RS15045
gene id: 414996:CDG81_RS15045
uniprot id: A0A223RU63
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

414996:CDG81 RS05500
gene id: 414996:CDG81_RS05500
uniprot id: A0A099D3C1
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

414996:CDG81 RS16755
gene id: 414996:CDG81_RS16755
uniprot id: A0A099D0S8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

414996:CDG81 RS21870
gene id: 414996:CDG81_RS21870
uniprot id: A0A099D9T5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

414996:CDG81 RS07250
gene id: 414996:CDG81_RS07250
uniprot id: A0A099D755
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

414996:CDG81 RS14315
gene id: 414996:CDG81_RS14315
uniprot id: A0A099D484
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS09250
gene id: 414996:CDG81_RS09250
uniprot id: A0A099D7L9
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

414996:CDG81 RS04215
gene id: 414996:CDG81_RS04215
uniprot id: A0A099D5C8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

414996:CDG81 RS07975
gene id: 414996:CDG81_RS07975
uniprot id: A0A099D6K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

414996:CDG81 RS03035
gene id: 414996:CDG81_RS03035
uniprot id: A0A099D2P3
names: Similarity
messages: Belongs to the peptidase S8 family.

414996:CDG81 RS18280
gene id: 414996:CDG81_RS18280
uniprot id: A0A099DAK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS10115
gene id: 414996:CDG81_RS10115
uniprot id: A0A099D6F6
names: Similarity
messages: Belongs to the glutamate synthase family.

414996:CDG81 RS22460
gene id: 414996:CDG81_RS22460
uniprot id: A0A099D9A4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS20545
gene id: 414996:CDG81_RS20545
uniprot id: A0A099D926
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS19005
gene id: 414996:CDG81_RS19005
uniprot id: A0A099D7X8
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

414996:CDG81 RS19980
gene id: 414996:CDG81_RS19980
uniprot id: A0A099D8L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

414996:CDG81 RS02385
gene id: 414996:CDG81_RS02385
uniprot id: A0A099D2I7
names: Subcellular Location Annotation
messages: Cytoplasm

414996:CDG81 RS07205
gene id: 414996:CDG81_RS07205
uniprot id: A0A099D6V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

414996:CDG81 RS08075
gene id: 414996:CDG81_RS08075
uniprot id: A0A099D6X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

414996:CDG81 RS20235
gene id: 414996:CDG81_RS20235
uniprot id: A0A099D8F7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

414996:CDG81 RS08245
gene id: 414996:CDG81_RS08245
uniprot id: A0A099D6U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

414996:CDG81 RS17515
gene id: 414996:CDG81_RS17515
uniprot id: A0A099D155
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

414996:CDG81 RS08190
gene id: 414996:CDG81_RS08190
uniprot id: A0A099D6G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS14970
gene id: 414996:CDG81_RS14970
uniprot id: A0A099D620
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS20420
gene id: 414996:CDG81_RS20420
uniprot id: A0A099DBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

414996:CDG81 RS06905
gene id: 414996:CDG81_RS06905
uniprot id: A0A099D6B7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

414996:CDG81 RS07185
gene id: 414996:CDG81_RS07185
uniprot id: A0A099D8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

414996:CDG81 RS04920
gene id: 414996:CDG81_RS04920
uniprot id: A0A099D3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

414996:CDG81 RS19540
gene id: 414996:CDG81_RS19540
uniprot id: A0A099D814
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

414996:CDG81 RS21840
gene id: 414996:CDG81_RS21840
uniprot id: A0A099D9T9
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

414996:CDG81 RS14240
gene id: 414996:CDG81_RS14240
uniprot id: A0A099D497
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

414996:CDG81 RS19445
gene id: 414996:CDG81_RS19445
uniprot id: A0A099D827
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

414996:CDG81 RS03815
gene id: 414996:CDG81_RS03815
uniprot id: A0A099D2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

414996:CDG81 RS14440
gene id: 414996:CDG81_RS14440
uniprot id: A0A223RTV7
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS03320
gene id: 414996:CDG81_RS03320
uniprot id: A0A099D2I9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

414996:CDG81 RS06850
gene id: 414996:CDG81_RS06850
uniprot id: A0A099D6C5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

414996:CDG81 RS19160
gene id: 414996:CDG81_RS19160
uniprot id: A0A099D8V2
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS08100
gene id: 414996:CDG81_RS08100
uniprot id: A0A099D8P3
names: Similarity
messages: Belongs to the TrpC family.

414996:CDG81 RS18520
gene id: 414996:CDG81_RS18520
uniprot id: A0A099DAF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

414996:CDG81 RS17600
gene id: 414996:CDG81_RS17600
uniprot id: A0A099D2R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

414996:CDG81 RS05260
gene id: 414996:CDG81_RS05260
uniprot id: A0A099D2P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

414996:CDG81 RS07900
gene id: 414996:CDG81_RS07900
uniprot id: A0A099D7L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

414996:CDG81 RS11190
gene id: 414996:CDG81_RS11190
uniprot id: A0A099D695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS07265
gene id: 414996:CDG81_RS07265
uniprot id: A0A099D6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

414996:CDG81 RS09930
gene id: 414996:CDG81_RS09930
uniprot id: A0A223RRR8
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

414996:CDG81 RS03545
gene id: 414996:CDG81_RS03545
uniprot id: A0A099D3H6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS08715
gene id: 414996:CDG81_RS08715
uniprot id: A0A099D7H4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS15480
gene id: 414996:CDG81_RS15480
uniprot id: A0A099D531
names: Similarity
messages: Belongs to the universal stress protein A family.

414996:CDG81 RS06955
gene id: 414996:CDG81_RS06955
uniprot id: A0A099D6Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

414996:CDG81 RS15665
gene id: 414996:CDG81_RS15665
uniprot id: A0A099D4D5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

414996:CDG81 RS02420
gene id: 414996:CDG81_RS02420
uniprot id: A0A099D496
names: Subcellular Location Annotation
messages: Cytoplasm

414996:CDG81 RS19565
gene id: 414996:CDG81_RS19565
uniprot id: A0A099D810
names: Similarity
messages: Belongs to the hyi family.

414996:CDG81 RS19955
gene id: 414996:CDG81_RS19955
uniprot id: A0A099D8M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

414996:CDG81 RS01105
gene id: 414996:CDG81_RS01105
uniprot id: A0A099DCK5
names: Similarity
messages: Belongs to the FGGY kinase family.

414996:CDG81 RS09215
gene id: 414996:CDG81_RS09215
uniprot id: A0A223RYP8
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS19705
gene id: 414996:CDG81_RS19705
uniprot id: A0A099D8U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

414996:CDG81 RS11755
gene id: 414996:CDG81_RS11755
uniprot id: A0A099D599
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS22250
gene id: 414996:CDG81_RS22250
uniprot id: A0A099D9D4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS04300
gene id: 414996:CDG81_RS04300
uniprot id: A0A099D2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

414996:CDG81 RS09890
gene id: 414996:CDG81_RS09890
uniprot id: A0A099D8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

414996:CDG81 RS20875
gene id: 414996:CDG81_RS20875
uniprot id: A0A099DA15
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

414996:CDG81 RS08830
gene id: 414996:CDG81_RS08830
uniprot id: A0A099D7E8
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

414996:CDG81 RS01860
gene id: 414996:CDG81_RS01860
uniprot id: A0A099D364
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

414996:CDG81 RS06450
gene id: 414996:CDG81_RS06450
uniprot id: A0A099D139
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

414996:CDG81 RS19695
gene id: 414996:CDG81_RS19695
uniprot id: A0A099DB05
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

414996:CDG81 RS00445
gene id: 414996:CDG81_RS00445
uniprot id: A0A099DBE7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

414996:CDG81 RS20245
gene id: 414996:CDG81_RS20245
uniprot id: A0A099D930
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

414996:CDG81 RS07115
gene id: 414996:CDG81_RS07115
uniprot id: A0A099D778
names: Similarity
messages: Belongs to the acylphosphatase family.

414996:CDG81 RS16760
gene id: 414996:CDG81_RS16760
uniprot id: A0A099D0G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

414996:CDG81 RS05430
gene id: 414996:CDG81_RS05430
uniprot id: A0A099D193
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

414996:CDG81 RS13210
gene id: 414996:CDG81_RS13210
uniprot id: A0A099D5G7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

414996:CDG81 RS18195
gene id: 414996:CDG81_RS18195
uniprot id: A0A099D167
names: Similarity
messages: Belongs to the FBPase class 2 family.

414996:CDG81 RS20010
gene id: 414996:CDG81_RS20010
uniprot id: A0A099D9J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

414996:CDG81 RS14105
gene id: 414996:CDG81_RS14105
uniprot id: A0A099D4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

414996:CDG81 RS14895
gene id: 414996:CDG81_RS14895
uniprot id: A0A099D635
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

414996:CDG81 RS07135
gene id: 414996:CDG81_RS07135
uniprot id: A0A099D8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

414996:CDG81 RS12050
gene id: 414996:CDG81_RS12050
uniprot id: A0A099D4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

414996:CDG81 RS02335
gene id: 414996:CDG81_RS02335
uniprot id: A0A099D2J3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

414996:CDG81 RS14395
gene id: 414996:CDG81_RS14395
uniprot id: A0A099D5U4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

414996:CDG81 RS04480
gene id: 414996:CDG81_RS04480
uniprot id: A0A099D2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS08450
gene id: 414996:CDG81_RS08450
uniprot id: A0A099D797
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS10135
gene id: 414996:CDG81_RS10135
uniprot id: A0A223RYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS05215
gene id: 414996:CDG81_RS05215
uniprot id: A0A099D1J4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

414996:CDG81 RS23130
gene id: 414996:CDG81_RS23130
uniprot id: A0A099DB22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

414996:CDG81 RS09725
gene id: 414996:CDG81_RS09725
uniprot id: A0A099D820
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS19950
gene id: 414996:CDG81_RS19950
uniprot id: A0A099D8W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

414996:CDG81 RS21560
gene id: 414996:CDG81_RS21560
uniprot id: A0A099D9Q1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

414996:CDG81 RS07220
gene id: 414996:CDG81_RS07220
uniprot id: A0A099D677
names: Similarity
messages: Belongs to the UPF0102 family.

414996:CDG81 RS00865
gene id: 414996:CDG81_RS00865
uniprot id: A0A099DBB8
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

414996:CDG81 RS19990
gene id: 414996:CDG81_RS19990
uniprot id: A0A099D985
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

414996:CDG81 RS14625
gene id: 414996:CDG81_RS14625
uniprot id: A0A099D3Q7
names: Similarity
messages: Belongs to the HupF/HypC family.

414996:CDG81 RS08365
gene id: 414996:CDG81_RS08365
uniprot id: A0A099D7Q6
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

414996:CDG81 RS09135
gene id: 414996:CDG81_RS09135
uniprot id: A0A099D890
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

414996:CDG81 RS10995
gene id: 414996:CDG81_RS10995
uniprot id: A0A099D7W1
names: Similarity
messages: Belongs to the EspG family.

414996:CDG81 RS20265
gene id: 414996:CDG81_RS20265
uniprot id: A0A099D8F1
names: Similarity
messages: Belongs to the UPF0336 family.

414996:CDG81 RS07635
gene id: 414996:CDG81_RS07635
uniprot id: A0A099D7R4
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS04040
gene id: 414996:CDG81_RS04040
uniprot id: A0A099D5E6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS18825
gene id: 414996:CDG81_RS18825
uniprot id: A0A099D913
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS06590
gene id: 414996:CDG81_RS06590
uniprot id: A0A099D0P1
names: Similarity
messages: Belongs to the fructosamine kinase family.

414996:CDG81 RS19265
gene id: 414996:CDG81_RS19265
uniprot id: A0A099D859
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

414996:CDG81 RS13645
gene id: 414996:CDG81_RS13645
uniprot id: A0A099D4C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

414996:CDG81 RS16070
gene id: 414996:CDG81_RS16070
uniprot id: A0A099D5K0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

414996:CDG81 RS14145
gene id: 414996:CDG81_RS14145
uniprot id: A0A099D3Y5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

414996:CDG81 RS05805
gene id: 414996:CDG81_RS05805
uniprot id: A0A099D1U1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

414996:CDG81 RS19945
gene id: 414996:CDG81_RS19945
uniprot id: A0A099DAU5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

414996:CDG81 RS04340
gene id: 414996:CDG81_RS04340
uniprot id: A0A099D215
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

414996:CDG81 RS03820
gene id: 414996:CDG81_RS03820
uniprot id: A0A099D3N2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS05400
gene id: 414996:CDG81_RS05400
uniprot id: A0A099D0S1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

414996:CDG81 RS05770
gene id: 414996:CDG81_RS05770
uniprot id: A0A099D248
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS15600
gene id: 414996:CDG81_RS15600
uniprot id: A0A099D6B4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

414996:CDG81 RS07225
gene id: 414996:CDG81_RS07225
uniprot id: A0A099D760
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

414996:CDG81 RS01225
gene id: 414996:CDG81_RS01225
uniprot id: A0A099DAE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

414996:CDG81 RS10900
gene id: 414996:CDG81_RS10900
uniprot id: A0A099D6J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

414996:CDG81 RS22960
gene id: 414996:CDG81_RS22960
uniprot id: A0A099DAT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

414996:CDG81 RS08040
gene id: 414996:CDG81_RS08040
uniprot id: A0A099D781
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

414996:CDG81 RS12085
gene id: 414996:CDG81_RS12085
uniprot id: A0A099D4X7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

414996:CDG81 RS14855
gene id: 414996:CDG81_RS14855
uniprot id: A0A099D4T2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

414996:CDG81 RS02285
gene id: 414996:CDG81_RS02285
uniprot id: A0A099D1V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

414996:CDG81 RS02395
gene id: 414996:CDG81_RS02395
uniprot id: A0A099D499
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

414996:CDG81 RS17305
gene id: 414996:CDG81_RS17305
uniprot id: A0A223RV28
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS10090
gene id: 414996:CDG81_RS10090
uniprot id: A0A099D6F3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

414996:CDG81 RS16490
gene id: 414996:CDG81_RS16490
uniprot id: A0A099D0E6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

414996:CDG81 RS18855
gene id: 414996:CDG81_RS18855
uniprot id: A0A099D909
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

414996:CDG81 RS08305
gene id: 414996:CDG81_RS08305
uniprot id: A0A099D6E4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

414996:CDG81 RS03985
gene id: 414996:CDG81_RS03985
uniprot id: A0A099D440
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

414996:CDG81 RS18910
gene id: 414996:CDG81_RS18910
uniprot id: A0A099D8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS10405
gene id: 414996:CDG81_RS10405
uniprot id: A0A099D7K7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

414996:CDG81 RS04220
gene id: 414996:CDG81_RS04220
uniprot id: A0A099D3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS13165
gene id: 414996:CDG81_RS13165
uniprot id: A0A099D5H9
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS19515
gene id: 414996:CDG81_RS19515
uniprot id: A0A099D8Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

414996:CDG81 RS02820
gene id: 414996:CDG81_RS02820
uniprot id: A0A099D2F1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

414996:CDG81 RS17620
gene id: 414996:CDG81_RS17620
uniprot id: A0A223RZD4
names: Similarity
messages: Belongs to the peptidase S1C family.

414996:CDG81 RS03420
gene id: 414996:CDG81_RS03420
uniprot id: A0A099D3K3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

414996:CDG81 RS06885
gene id: 414996:CDG81_RS06885
uniprot id: A0A099D7B2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS17820
gene id: 414996:CDG81_RS17820
uniprot id: A0A099D2W8
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS10920
gene id: 414996:CDG81_RS10920
uniprot id: A0A223RS92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS01945
gene id: 414996:CDG81_RS01945
uniprot id: A0A223RN36
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

414996:CDG81 RS22890
gene id: 414996:CDG81_RS22890
uniprot id: A0A099DC14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

414996:CDG81 RS07375
gene id: 414996:CDG81_RS07375
uniprot id: A0A223RQL3
names: Subcellular Location Annotation
messages: Membrane

414996:CDG81 RS20445
gene id: 414996:CDG81_RS20445
uniprot id: A0A099D9T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

414996:CDG81 RS03135
gene id: 414996:CDG81_RS03135
uniprot id: A0A099D4Q3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

414996:CDG81 RS08590
gene id: 414996:CDG81_RS08590
uniprot id: A0A099D9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

414996:CDG81 RS06165
gene id: 414996:CDG81_RS06165
uniprot id: A0A099D0H4
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

414996:CDG81 RS04525
gene id: 414996:CDG81_RS04525
uniprot id: A0A099D445
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

414996:CDG81 RS09535
gene id: 414996:CDG81_RS09535
uniprot id: A0A223RRI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

414996:CDG81 RS05115
gene id: 414996:CDG81_RS05115
uniprot id: A0A099D1G8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

414996:CDG81 RS08080
gene id: 414996:CDG81_RS08080
uniprot id: A0A223RQX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

414996:CDG81 RS02865
gene id: 414996:CDG81_RS02865
uniprot id: A0A099D4U6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

414996:CDG81 RS07230
gene id: 414996:CDG81_RS07230
uniprot id: A0A099D6U8
names: Similarity
messages: Belongs to the DprA/Smf family.

414996:CDG81 RS05615
gene id: 414996:CDG81_RS05615
uniprot id: A0A099D1Q4
names: Subcellular Location Annotation
messages: Cytoplasm

414996:CDG81 RS02265
gene id: 414996:CDG81_RS02265
uniprot id: A0A099D300
names: Similarity
messages: Belongs to the peptidase S1 family.

414996:CDG81 RS08560
gene id: 414996:CDG81_RS08560
uniprot id: A0A099D7K1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

414996:CDG81 RS06665
gene id: 414996:CDG81_RS06665
uniprot id: A0A099D166
names: Similarity
messages: Belongs to the peptidase C40 family.

414996:CDG81 RS09000
gene id: 414996:CDG81_RS09000
uniprot id: A0A223RRA2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

414996:CDG81 RS09925
gene id: 414996:CDG81_RS09925
uniprot id: A0A099D9K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

414996:CDG81 RS01345
gene id: 414996:CDG81_RS01345
uniprot id: A0A223RMT4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

414996:CDG81 RS09075
gene id: 414996:CDG81_RS09075
uniprot id: A0A099D7N8
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

414996:CDG81 RS16265
gene id: 414996:CDG81_RS16265
uniprot id: A0A099D4X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

414996:CDG81 RS19555
gene id: 414996:CDG81_RS19555
uniprot id: A0A099D9X9
names: Similarity
messages: Belongs to the HIBADH-related family.

414996:CDG81 RS20230
gene id: 414996:CDG81_RS20230
uniprot id: A0A099D8S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

414996:CDG81 RS14945
gene id: 414996:CDG81_RS14945
uniprot id: A0A099D624
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

414996:CDG81 RS12900
gene id: 414996:CDG81_RS12900
uniprot id: A0A099D720
names: Similarity
messages: Belongs to the terpene synthase family.

414996:CDG81 RS20375
gene id: 414996:CDG81_RS20375
uniprot id: A0A099D8C9
names: Similarity
messages: Belongs to the UPF0234 family.

414996:CDG81 RS07640
gene id: 414996:CDG81_RS07640
uniprot id: A0A099D7F0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

414996:CDG81 RS13670
gene id: 414996:CDG81_RS13670
uniprot id: A0A099D3A6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

414996:CDG81 RS16300
gene id: 414996:CDG81_RS16300
uniprot id: A0A099D5H4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

414996:CDG81 RS04615
gene id: 414996:CDG81_RS04615
uniprot id: A0A099D457
names: Similarity
messages: Belongs to the EspG family.

414996:CDG81 RS14840
gene id: 414996:CDG81_RS14840
uniprot id: A0A099D645
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

414996:CDG81 RS00805
gene id: 414996:CDG81_RS00805
uniprot id: A0A223RMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

414996:CDG81 RS00655
gene id: 414996:CDG81_RS00655
uniprot id: A0A099DAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

414996:CDG81 RS07290
gene id: 414996:CDG81_RS07290
uniprot id: A0A099D8C3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

414996:CDG81 RS07035
gene id: 414996:CDG81_RS07035
uniprot id: A0A099D790
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

414996:CDG81 RS07545
gene id: 414996:CDG81_RS07545
uniprot id: A0A099D798
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

414996:CDG81 RS07940
gene id: 414996:CDG81_RS07940
uniprot id: A0A099D8S2
names: Similarity
messages: Belongs to the cytochrome P450 family.

414996:CDG81 RS18285
gene id: 414996:CDG81_RS18285
uniprot id: A0A223RVI8
names: Subunit
messages: Homodimer.

414996:CDG81 RS11300
gene id: 414996:CDG81_RS11300
uniprot id: A0A099D843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane