412418:BRE RS00300
gene id: 412418:BRE_RS00300
uniprot id: B5RQN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS05080
gene id: 412418:BRE_RS05080
uniprot id: B5RS48
names: Function
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS05755
gene id: 412418:BRE_RS05755
uniprot id: B5RS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS03475
gene id: 412418:BRE_RS03475
uniprot id: B5RQ27
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

412418:BRE RS02190
gene id: 412418:BRE_RS02190
uniprot id: B5RRN6
names: Similarity
messages: Belongs to the ParB family.

412418:BRE RS03480
gene id: 412418:BRE_RS03480
uniprot id: B5RQ28
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

412418:BRE RS04040
gene id: 412418:BRE_RS04040
uniprot id: B5RQD1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

412418:BRE RS02400
gene id: 412418:BRE_RS02400
uniprot id: B5RRS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

412418:BRE RS01465
gene id: 412418:BRE_RS01465
uniprot id: B5RRA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

412418:BRE RS02500
gene id: 412418:BRE_RS02500
uniprot id: B5RPJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

412418:BRE RS00135
gene id: 412418:BRE_RS00135
uniprot id: B5RQJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

412418:BRE RS01340
gene id: 412418:BRE_RS01340
uniprot id: B5RR73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

412418:BRE RS02990
gene id: 412418:BRE_RS02990
uniprot id: B5RPT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

412418:BRE RS00150
gene id: 412418:BRE_RS00150
uniprot id: B5RQK1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

412418:BRE RS02545
gene id: 412418:BRE_RS02545
uniprot id: B5RPK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

412418:BRE RS01430
gene id: 412418:BRE_RS01430
uniprot id: B5RR94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

412418:BRE RS01540
gene id: 412418:BRE_RS01540
uniprot id: B5RRB6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

412418:BRE RS00145
gene id: 412418:BRE_RS00145
uniprot id: B5RQK0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

412418:BRE RS05740
gene id: 412418:BRE_RS05740
uniprot id: B5RS52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS02085
gene id: 412418:BRE_RS02085
uniprot id: B5RRM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS01480
gene id: 412418:BRE_RS01480
uniprot id: B5RRA4
names: Similarity
messages: Belongs to the FlgD family.

412418:BRE RS01700
gene id: 412418:BRE_RS01700
uniprot id: B5RRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

412418:BRE RS02225
gene id: 412418:BRE_RS02225
uniprot id: B5RRP3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

412418:BRE RS03725
gene id: 412418:BRE_RS03725
uniprot id: B5RQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

412418:BRE RS03045
gene id: 412418:BRE_RS03045
uniprot id: B5RPU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

412418:BRE RS00700
gene id: 412418:BRE_RS00700
uniprot id: B5RQV7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

412418:BRE RS03845
gene id: 412418:BRE_RS03845
uniprot id: B5RQ94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

412418:BRE RS00615
gene id: 412418:BRE_RS00615
uniprot id: B5RQU2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

412418:BRE RS01345
gene id: 412418:BRE_RS01345
uniprot id: B5RR77
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

412418:BRE RS00605
gene id: 412418:BRE_RS00605
uniprot id: B5RQU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

412418:BRE RS03670
gene id: 412418:BRE_RS03670
uniprot id: B5RQ63
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS01420
gene id: 412418:BRE_RS01420
uniprot id: B5RR92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

412418:BRE RS04225
gene id: 412418:BRE_RS04225
uniprot id: B5RQG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

412418:BRE RS04175
gene id: 412418:BRE_RS04175
uniprot id: B5RQF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS02395
gene id: 412418:BRE_RS02395
uniprot id: B5RRS3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

412418:BRE RS00640
gene id: 412418:BRE_RS00640
uniprot id: B5RQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

412418:BRE RS03630
gene id: 412418:BRE_RS03630
uniprot id: B5RQ55
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

412418:BRE RS04000
gene id: 412418:BRE_RS04000
uniprot id: B5RQC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

412418:BRE RS03100
gene id: 412418:BRE_RS03100
uniprot id: B5RPV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

412418:BRE RS00440
gene id: 412418:BRE_RS00440
uniprot id: B5RQQ9
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS03570
gene id: 412418:BRE_RS03570
uniprot id: B5RQ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

412418:BRE RS02795
gene id: 412418:BRE_RS02795
uniprot id: B5RPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

412418:BRE RS01140
gene id: 412418:BRE_RS01140
uniprot id: B5RR42
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

412418:BRE RS03270
gene id: 412418:BRE_RS03270
uniprot id: B5RPY6
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

412418:BRE RS01515
gene id: 412418:BRE_RS01515
uniprot id: B5RRB1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane

412418:BRE RS05125
gene id: 412418:BRE_RS05125
uniprot id: B5RS52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS05440
gene id: 412418:BRE_RS05440
uniprot id: B5RS84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS02615
gene id: 412418:BRE_RS02615
uniprot id: B5RPL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

412418:BRE RS04880
gene id: 412418:BRE_RS04880
uniprot id: B5RS18
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

412418:BRE RS00960
gene id: 412418:BRE_RS00960
uniprot id: B5RR09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

412418:BRE RS02095
gene id: 412418:BRE_RS02095
uniprot id: B5RRM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

412418:BRE RS00535
gene id: 412418:BRE_RS00535
uniprot id: B5RQS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

412418:BRE RS01450
gene id: 412418:BRE_RS01450
uniprot id: B5RR98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

412418:BRE RS02260
gene id: 412418:BRE_RS02260
uniprot id: B5RRQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

412418:BRE RS01020
gene id: 412418:BRE_RS01020
uniprot id: B5RR21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

412418:BRE RS04265
gene id: 412418:BRE_RS04265
uniprot id: B5RQH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

412418:BRE RS05680
gene id: 412418:BRE_RS05680
uniprot id: B5RS77
names: Function
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS02515
gene id: 412418:BRE_RS02515
uniprot id: B5RPJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

412418:BRE RS03605
gene id: 412418:BRE_RS03605
uniprot id: B5RQ50
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

412418:BRE RS03240
gene id: 412418:BRE_RS03240
uniprot id: B5RPY0
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS01955
gene id: 412418:BRE_RS01955
uniprot id: B5RRJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

412418:BRE RS02540
gene id: 412418:BRE_RS02540
uniprot id: B5RPK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

412418:BRE RS02580
gene id: 412418:BRE_RS02580
uniprot id: B5RPL0
names: Similarity
messages: Belongs to the TlyA family.

412418:BRE RS01630
gene id: 412418:BRE_RS01630
uniprot id: B5RRD3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

412418:BRE RS00510
gene id: 412418:BRE_RS00510
uniprot id: B5RQS2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

412418:BRE RS02480
gene id: 412418:BRE_RS02480
uniprot id: B5RPJ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

412418:BRE RS03555
gene id: 412418:BRE_RS03555
uniprot id: B5RQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

412418:BRE RS00200
gene id: 412418:BRE_RS00200
uniprot id: B5RQL1
names: Similarity
messages: Belongs to the UPF0178 family.

412418:BRE RS00920
gene id: 412418:BRE_RS00920
uniprot id: B5RR01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasmic flagellum

412418:BRE RS01725
gene id: 412418:BRE_RS01725
uniprot id: B5RRF1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

412418:BRE RS00385
gene id: 412418:BRE_RS00385
uniprot id: B5RQP8
names: Similarity
messages: Belongs to the peptidase M29 family.

412418:BRE RS03965
gene id: 412418:BRE_RS03965
uniprot id: B5RQB7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

412418:BRE RS00600
gene id: 412418:BRE_RS00600
uniprot id: B5RQT9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

412418:BRE RS03460
gene id: 412418:BRE_RS03460
uniprot id: B5RQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

412418:BRE RS05465
gene id: 412418:BRE_RS05465
uniprot id: B5RS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS01945
gene id: 412418:BRE_RS01945
uniprot id: B5RRJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

412418:BRE RS04125
gene id: 412418:BRE_RS04125
uniprot id: B5RQE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

412418:BRE RS02635
gene id: 412418:BRE_RS02635
uniprot id: B5RPM1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

412418:BRE RS03655
gene id: 412418:BRE_RS03655
uniprot id: B5RQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

412418:BRE RS03970
gene id: 412418:BRE_RS03970
uniprot id: B5RQB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

412418:BRE RS00240
gene id: 412418:BRE_RS00240
uniprot id: B5RQL9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

412418:BRE RS04310
gene id: 412418:BRE_RS04310
uniprot id: B5RQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

412418:BRE RS00955
gene id: 412418:BRE_RS00955
uniprot id: B5RR08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

412418:BRE RS00625
gene id: 412418:BRE_RS00625
uniprot id: B5RQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

412418:BRE RS02215
gene id: 412418:BRE_RS02215
uniprot id: B5RRP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

412418:BRE RS00500
gene id: 412418:BRE_RS00500
uniprot id: B5RQS0
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

412418:BRE RS04220
gene id: 412418:BRE_RS04220
uniprot id: B5RQG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

412418:BRE RS02000
gene id: 412418:BRE_RS02000
uniprot id: B5RRK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

412418:BRE RS04990
gene id: 412418:BRE_RS04990
uniprot id: B5RS36
names: Function
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS03795
gene id: 412418:BRE_RS03795
uniprot id: B5RQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

412418:BRE RS03915
gene id: 412418:BRE_RS03915
uniprot id: B5RQA7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

412418:BRE RS02570
gene id: 412418:BRE_RS02570
uniprot id: B5RPK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

412418:BRE RS01530
gene id: 412418:BRE_RS01530
uniprot id: B5RRB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

412418:BRE RS02945
gene id: 412418:BRE_RS02945
uniprot id: B5RPS9
names: Subcellular Location Annotation
messages: Cytoplasm

412418:BRE RS01985
gene id: 412418:BRE_RS01985
uniprot id: B5RRK2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

412418:BRE RS00325
gene id: 412418:BRE_RS00325
uniprot id: B5RQN6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

412418:BRE RS03905
gene id: 412418:BRE_RS03905
uniprot id: B5RQA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

412418:BRE RS01200
gene id: 412418:BRE_RS01200
uniprot id: B5RR54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

412418:BRE RS00350
gene id: 412418:BRE_RS00350
uniprot id: B5RQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

412418:BRE RS02620
gene id: 412418:BRE_RS02620
uniprot id: B5RPL8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

412418:BRE RS00365
gene id: 412418:BRE_RS00365
uniprot id: B5RQP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

412418:BRE RS00715
gene id: 412418:BRE_RS00715
uniprot id: B5RQW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

412418:BRE RS03540
gene id: 412418:BRE_RS03540
uniprot id: B5RQ39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

412418:BRE RS00375
gene id: 412418:BRE_RS00375
uniprot id: B5RQP6
names: Similarity
messages: Belongs to the peptidase M24B family.

412418:BRE RS03110
gene id: 412418:BRE_RS03110
uniprot id: B5RPV8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

412418:BRE RS01970
gene id: 412418:BRE_RS01970
uniprot id: B5RRJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

412418:BRE RS04115
gene id: 412418:BRE_RS04115
uniprot id: B5RQE5
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS01225
gene id: 412418:BRE_RS01225
uniprot id: B5RR58
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS00280
gene id: 412418:BRE_RS00280
uniprot id: B5RQM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

412418:BRE RS00205
gene id: 412418:BRE_RS00205
uniprot id: B5RQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

412418:BRE RS03625
gene id: 412418:BRE_RS03625
uniprot id: B5RQ54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS00175
gene id: 412418:BRE_RS00175
uniprot id: B5RQK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

412418:BRE RS02065
gene id: 412418:BRE_RS02065
uniprot id: B5RRL6
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

412418:BRE RS03505
gene id: 412418:BRE_RS03505
uniprot id: B5RQ32
names: Similarity
messages: Belongs to the Dps family.

412418:BRE RS01190
gene id: 412418:BRE_RS01190
uniprot id: B5RR52
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

412418:BRE RS03685
gene id: 412418:BRE_RS03685
uniprot id: B5RQ66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

412418:BRE RS00855
gene id: 412418:BRE_RS00855
uniprot id: B5RQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

412418:BRE RS04130
gene id: 412418:BRE_RS04130
uniprot id: B5RQE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

412418:BRE RS04185
gene id: 412418:BRE_RS04185
uniprot id: B5RQF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

412418:BRE RS00180
gene id: 412418:BRE_RS00180
uniprot id: B5RQK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

412418:BRE RS02980
gene id: 412418:BRE_RS02980
uniprot id: B5RPT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

412418:BRE RS00170
gene id: 412418:BRE_RS00170
uniprot id: B5RQK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

412418:BRE RS01860
gene id: 412418:BRE_RS01860
uniprot id: B5RRH8
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

412418:BRE RS00090
gene id: 412418:BRE_RS00090
uniprot id: B5RQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

412418:BRE RS03120
gene id: 412418:BRE_RS03120
uniprot id: B5RPW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

412418:BRE RS00305
gene id: 412418:BRE_RS00305
uniprot id: B5RQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

412418:BRE RS01510
gene id: 412418:BRE_RS01510
uniprot id: B5RRB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

412418:BRE RS00340
gene id: 412418:BRE_RS00340
uniprot id: B5RQN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

412418:BRE RS01175
gene id: 412418:BRE_RS01175
uniprot id: B5RR49
names: Function
names: Similarity
messages: Belongs to the bacterial histone-like protein family.
messages: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.

412418:BRE RS03340
gene id: 412418:BRE_RS03340
uniprot id: B5RQ00
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

412418:BRE RS00460
gene id: 412418:BRE_RS00460
uniprot id: B5RQR2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

412418:BRE RS02495
gene id: 412418:BRE_RS02495
uniprot id: B5RPJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

412418:BRE RS01840
gene id: 412418:BRE_RS01840
uniprot id: B5RRH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

412418:BRE RS01590
gene id: 412418:BRE_RS01590
uniprot id: B5RRC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

412418:BRE RS01460
gene id: 412418:BRE_RS01460
uniprot id: B5RRA0
names: Similarity
messages: Belongs to the MotB family.

412418:BRE RS03645
gene id: 412418:BRE_RS03645
uniprot id: B5RQ58
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS00895
gene id: 412418:BRE_RS00895
uniprot id: B5RQZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

412418:BRE RS04105
gene id: 412418:BRE_RS04105
uniprot id: B5RQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

412418:BRE RS00760
gene id: 412418:BRE_RS00760
uniprot id: B5RQW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

412418:BRE RS01270
gene id: 412418:BRE_RS01270
uniprot id: B5RR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

412418:BRE RS00780
gene id: 412418:BRE_RS00780
uniprot id: B5RQX3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

412418:BRE RS02565
gene id: 412418:BRE_RS02565
uniprot id: B5RPK7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

412418:BRE RS02785
gene id: 412418:BRE_RS02785
uniprot id: B5RPP8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

412418:BRE RS00985
gene id: 412418:BRE_RS00985
uniprot id: B5RR15
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

412418:BRE RS01980
gene id: 412418:BRE_RS01980
uniprot id: B5RRK1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

412418:BRE RS01100
gene id: 412418:BRE_RS01100
uniprot id: B5RR34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

412418:BRE RS01625
gene id: 412418:BRE_RS01625
uniprot id: B5RRD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

412418:BRE RS01015
gene id: 412418:BRE_RS01015
uniprot id: B5RR20
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS03520
gene id: 412418:BRE_RS03520
uniprot id: B5RQ35
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

412418:BRE RS02440
gene id: 412418:BRE_RS02440
uniprot id: B5RPI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

412418:BRE RS02910
gene id: 412418:BRE_RS02910
uniprot id: B5RPS2
names: Similarity
messages: Belongs to the UMP kinase family.

412418:BRE RS04250
gene id: 412418:BRE_RS04250
uniprot id: B5RQH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

412418:BRE RS03440
gene id: 412418:BRE_RS03440
uniprot id: B5RQ20
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS02700
gene id: 412418:BRE_RS02700
uniprot id: B5RPN4
names: Similarity
messages: Belongs to the peptidase M16 family.

412418:BRE RS02550
gene id: 412418:BRE_RS02550
uniprot id: B5RPK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

412418:BRE RS03205
gene id: 412418:BRE_RS03205
uniprot id: B5RPX4
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

412418:BRE RS00545
gene id: 412418:BRE_RS00545
uniprot id: B5RQS8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

412418:BRE RS01050
gene id: 412418:BRE_RS01050
uniprot id: B5RR25
names: Similarity
messages: Belongs to the UDPGP type 2 family.

412418:BRE RS02950
gene id: 412418:BRE_RS02950
uniprot id: B5RPT0
names: Similarity
messages: Belongs to the YggT family.

412418:BRE RS02630
gene id: 412418:BRE_RS02630
uniprot id: B5RPM0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

412418:BRE RS02415
gene id: 412418:BRE_RS02415
uniprot id: B5RRS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS02235
gene id: 412418:BRE_RS02235
uniprot id: B5RRP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

412418:BRE RS05360
gene id: 412418:BRE_RS05360
uniprot id: B5RS72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS04005
gene id: 412418:BRE_RS04005
uniprot id: B5RQC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

412418:BRE RS00595
gene id: 412418:BRE_RS00595
uniprot id: B5RQT8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

412418:BRE RS00790
gene id: 412418:BRE_RS00790
uniprot id: B5RQX5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

412418:BRE RS01870
gene id: 412418:BRE_RS01870
uniprot id: B5RRH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

412418:BRE RS02520
gene id: 412418:BRE_RS02520
uniprot id: B5RPJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

412418:BRE RS02460
gene id: 412418:BRE_RS02460
uniprot id: B5RPI6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

412418:BRE RS03295
gene id: 412418:BRE_RS03295
uniprot id: B5RPZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

412418:BRE RS03745
gene id: 412418:BRE_RS03745
uniprot id: B5RQ78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

412418:BRE RS02435
gene id: 412418:BRE_RS02435
uniprot id: B5RPI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

412418:BRE RS02050
gene id: 412418:BRE_RS02050
uniprot id: B5RRL3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

412418:BRE RS02485
gene id: 412418:BRE_RS02485
uniprot id: B5RPJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

412418:BRE RS04940
gene id: 412418:BRE_RS04940
uniprot id: B5RS26
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS01145
gene id: 412418:BRE_RS01145
uniprot id: B5RR43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

412418:BRE RS01750
gene id: 412418:BRE_RS01750
uniprot id: B5RRF6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

412418:BRE RS03235
gene id: 412418:BRE_RS03235
uniprot id: B5RPX9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS01260
gene id: 412418:BRE_RS01260
uniprot id: B5RR64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

412418:BRE RS02055
gene id: 412418:BRE_RS02055
uniprot id: B5RRL4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

412418:BRE RS02490
gene id: 412418:BRE_RS02490
uniprot id: B5RPJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

412418:BRE RS04075
gene id: 412418:BRE_RS04075
uniprot id: B5RQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

412418:BRE RS00110
gene id: 412418:BRE_RS00110
uniprot id: B5RQJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

412418:BRE RS02455
gene id: 412418:BRE_RS02455
uniprot id: B5RPI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

412418:BRE RS05550
gene id: 412418:BRE_RS05550
uniprot id: B5RS95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS01900
gene id: 412418:BRE_RS01900
uniprot id: B5RRI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS00775
gene id: 412418:BRE_RS00775
uniprot id: B5RQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Periplasm
messages: Periplasmic flagellum
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.

412418:BRE RS00120
gene id: 412418:BRE_RS00120
uniprot id: B5RQJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

412418:BRE RS02450
gene id: 412418:BRE_RS02450
uniprot id: B5RPI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

412418:BRE RS03560
gene id: 412418:BRE_RS03560
uniprot id: B5RQ43
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

412418:BRE RS04015
gene id: 412418:BRE_RS04015
uniprot id: B5RQC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

412418:BRE RS02135
gene id: 412418:BRE_RS02135
uniprot id: B5RRM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

412418:BRE RS02765
gene id: 412418:BRE_RS02765
uniprot id: B5RPP4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

412418:BRE RS02390
gene id: 412418:BRE_RS02390
uniprot id: B5RRS2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

412418:BRE RS03445
gene id: 412418:BRE_RS03445
uniprot id: B5RQ21
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS03230
gene id: 412418:BRE_RS03230
uniprot id: B5RPX8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

412418:BRE RS02850
gene id: 412418:BRE_RS02850
uniprot id: B5RPR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

412418:BRE RS01990
gene id: 412418:BRE_RS01990
uniprot id: B5RRK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

412418:BRE RS05305
gene id: 412418:BRE_RS05305
uniprot id: B5RS67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS01025
gene id: 412418:BRE_RS01025
uniprot id: B5RR22
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

412418:BRE RS04535
gene id: 412418:BRE_RS04535
uniprot id: B5RRW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

412418:BRE RS01165
gene id: 412418:BRE_RS01165
uniprot id: B5RR47
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS01965
gene id: 412418:BRE_RS01965
uniprot id: B5RRJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

412418:BRE RS03285
gene id: 412418:BRE_RS03285
uniprot id: B5RPY9
names: Similarity
messages: Belongs to the Fur family.

412418:BRE RS02955
gene id: 412418:BRE_RS02955
uniprot id: B5RPT1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

412418:BRE RS03650
gene id: 412418:BRE_RS03650
uniprot id: B5RQ59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

412418:BRE RS02510
gene id: 412418:BRE_RS02510
uniprot id: B5RPJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

412418:BRE RS00930
gene id: 412418:BRE_RS00930
uniprot id: B5RR03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

412418:BRE RS02130
gene id: 412418:BRE_RS02130
uniprot id: B5RRM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

412418:BRE RS02560
gene id: 412418:BRE_RS02560
uniprot id: B5RPK6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

412418:BRE RS03695
gene id: 412418:BRE_RS03695
uniprot id: B5RQ68
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS02640
gene id: 412418:BRE_RS02640
uniprot id: B5RPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

412418:BRE RS01115
gene id: 412418:BRE_RS01115
uniprot id: B5RR37
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS01960
gene id: 412418:BRE_RS01960
uniprot id: B5RRJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

412418:BRE RS03825
gene id: 412418:BRE_RS03825
uniprot id: B5RQ90
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS01435
gene id: 412418:BRE_RS01435
uniprot id: B5RR95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

412418:BRE RS00490
gene id: 412418:BRE_RS00490
uniprot id: B5RQR8
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS00565
gene id: 412418:BRE_RS00565
uniprot id: B5RQT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

412418:BRE RS01160
gene id: 412418:BRE_RS01160
uniprot id: B5RR46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

412418:BRE RS01575
gene id: 412418:BRE_RS01575
uniprot id: B5RRC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

412418:BRE RS02740
gene id: 412418:BRE_RS02740
uniprot id: B5RPN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

412418:BRE RS01555
gene id: 412418:BRE_RS01555
uniprot id: B5RRB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

412418:BRE RS01215
gene id: 412418:BRE_RS01215
uniprot id: B5RR57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

412418:BRE RS01975
gene id: 412418:BRE_RS01975
uniprot id: B5RRK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

412418:BRE RS00320
gene id: 412418:BRE_RS00320
uniprot id: B5RQN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

412418:BRE RS01730
gene id: 412418:BRE_RS01730
uniprot id: B5RRF2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

412418:BRE RS04550
gene id: 412418:BRE_RS04550
uniprot id: B5RRW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS01350
gene id: 412418:BRE_RS01350
uniprot id: B5RR78
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

412418:BRE RS02210
gene id: 412418:BRE_RS02210
uniprot id: B5RRP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

412418:BRE RS01850
gene id: 412418:BRE_RS01850
uniprot id: B5RRH6
names: Similarity
messages: Belongs to the peptidase M18 family.

412418:BRE RS04210
gene id: 412418:BRE_RS04210
uniprot id: B5RQG3
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS02970
gene id: 412418:BRE_RS02970
uniprot id: B5RPT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

412418:BRE RS03255
gene id: 412418:BRE_RS03255
uniprot id: B5RPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

412418:BRE RS01935
gene id: 412418:BRE_RS01935
uniprot id: B5RRJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMP lipoprotein family.
messages: Cell membrane

412418:BRE RS05630
gene id: 412418:BRE_RS05630
uniprot id: B5RSA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: An outer membrane protein that may participate in pathogenesis. Some human Lyme disease patients have antibodies against this protein (PubMed:10948116). The Mlp proteins probably undergo intragenic recombination, generating new alleles.
messages: Belongs to the Multicopy lipoprotein (Mlp) family.
messages: Membrane

412418:BRE RS01735
gene id: 412418:BRE_RS01735
uniprot id: B5RRF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

412418:BRE RS02735
gene id: 412418:BRE_RS02735
uniprot id: B5RPN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

412418:BRE RS04260
gene id: 412418:BRE_RS04260
uniprot id: B5RQH2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

412418:BRE RS02250
gene id: 412418:BRE_RS02250
uniprot id: B5RRP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

412418:BRE RS02975
gene id: 412418:BRE_RS02975
uniprot id: B5RPT5
names: Similarity
messages: Belongs to the FemABX family.

412418:BRE RS03925
gene id: 412418:BRE_RS03925
uniprot id: B5RQA9
names: Function
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body

412418:BRE RS00635
gene id: 412418:BRE_RS00635
uniprot id: B5RQU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS01520
gene id: 412418:BRE_RS01520
uniprot id: B5RRB2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

412418:BRE RS01265
gene id: 412418:BRE_RS01265
uniprot id: B5RR65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

412418:BRE RS03530
gene id: 412418:BRE_RS03530
uniprot id: B5RQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

412418:BRE RS05390
gene id: 412418:BRE_RS05390
uniprot id: B5RS77
names: Function
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS02465
gene id: 412418:BRE_RS02465
uniprot id: B5RPI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

412418:BRE RS01425
gene id: 412418:BRE_RS01425
uniprot id: B5RR93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

412418:BRE RS00905
gene id: 412418:BRE_RS00905
uniprot id: B5RQZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

412418:BRE RS01415
gene id: 412418:BRE_RS01415
uniprot id: B5RR91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

412418:BRE RS02530
gene id: 412418:BRE_RS02530
uniprot id: B5RPK0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

412418:BRE RS03190
gene id: 412418:BRE_RS03190
uniprot id: B5RPX1
names: Similarity
messages: Belongs to the peptidase M18 family.

412418:BRE RS03010
gene id: 412418:BRE_RS03010
uniprot id: B5RPU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

412418:BRE RS01090
gene id: 412418:BRE_RS01090
uniprot id: B5RR32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

412418:BRE RS04270
gene id: 412418:BRE_RS04270
uniprot id: B5RQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

412418:BRE RS04095
gene id: 412418:BRE_RS04095
uniprot id: B5RQE1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

412418:BRE RS00430
gene id: 412418:BRE_RS00430
uniprot id: B5RQQ7
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS00315
gene id: 412418:BRE_RS00315
uniprot id: B5RQN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

412418:BRE RS01070
gene id: 412418:BRE_RS01070
uniprot id: B5RR29
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

412418:BRE RS01445
gene id: 412418:BRE_RS01445
uniprot id: B5RR97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

412418:BRE RS02555
gene id: 412418:BRE_RS02555
uniprot id: B5RPK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

412418:BRE RS01120
gene id: 412418:BRE_RS01120
uniprot id: B5RR38
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

412418:BRE RS02445
gene id: 412418:BRE_RS02445
uniprot id: B5RPI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

412418:BRE RS03935
gene id: 412418:BRE_RS03935
uniprot id: B5RQB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

412418:BRE RS02280
gene id: 412418:BRE_RS02280
uniprot id: B5RRQ4
names: Similarity
messages: Belongs to the sigma-54 factor family.

412418:BRE RS05730
gene id: 412418:BRE_RS05730
uniprot id: B5RS84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS01745
gene id: 412418:BRE_RS01745
uniprot id: B5RRF5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

412418:BRE RS03525
gene id: 412418:BRE_RS03525
uniprot id: B5RQ36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

412418:BRE RS00655
gene id: 412418:BRE_RS00655
uniprot id: B5RQU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

412418:BRE RS00940
gene id: 412418:BRE_RS00940
uniprot id: B5RR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

412418:BRE RS03310
gene id: 412418:BRE_RS03310
uniprot id: B5RPZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

412418:BRE RS02780
gene id: 412418:BRE_RS02780
uniprot id: B5RPP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

412418:BRE RS04055
gene id: 412418:BRE_RS04055
uniprot id: B5RQD4
names: Similarity
messages: Belongs to the Skp family.

412418:BRE RS04300
gene id: 412418:BRE_RS04300
uniprot id: B5RQI0
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS00210
gene id: 412418:BRE_RS00210
uniprot id: B5RQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

412418:BRE RS01645
gene id: 412418:BRE_RS01645
uniprot id: B5RRD6
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS03200
gene id: 412418:BRE_RS03200
uniprot id: B5RPX3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

412418:BRE RS00420
gene id: 412418:BRE_RS00420
uniprot id: B5RQQ5
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS01285
gene id: 412418:BRE_RS01285
uniprot id: B5RR68
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS00915
gene id: 412418:BRE_RS00915
uniprot id: B5RR00
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

412418:BRE RS01475
gene id: 412418:BRE_RS01475
uniprot id: B5RRA3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

412418:BRE RS02290
gene id: 412418:BRE_RS02290
uniprot id: B5RRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

412418:BRE RS02360
gene id: 412418:BRE_RS02360
uniprot id: B5RRR6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

412418:BRE RS04150
gene id: 412418:BRE_RS04150
uniprot id: B5RQF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

412418:BRE RS03515
gene id: 412418:BRE_RS03515
uniprot id: B5RQ34
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

412418:BRE RS01310
gene id: 412418:BRE_RS01310
uniprot id: B5RR73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

412418:BRE RS00160
gene id: 412418:BRE_RS00160
uniprot id: B5RQK3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

412418:BRE RS00925
gene id: 412418:BRE_RS00925
uniprot id: B5RR02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

412418:BRE RS00950
gene id: 412418:BRE_RS00950
uniprot id: B5RR07
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

412418:BRE RS03835
gene id: 412418:BRE_RS03835
uniprot id: B5RQ92
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

412418:BRE RS02285
gene id: 412418:BRE_RS02285
uniprot id: B5RRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

412418:BRE RS00645
gene id: 412418:BRE_RS00645
uniprot id: B5RQU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

412418:BRE RS00585
gene id: 412418:BRE_RS00585
uniprot id: B5RQT6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

412418:BRE RS01105
gene id: 412418:BRE_RS01105
uniprot id: B5RR35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

412418:BRE RS01950
gene id: 412418:BRE_RS01950
uniprot id: B5RRJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

412418:BRE RS03260
gene id: 412418:BRE_RS03260
uniprot id: B5RPY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

412418:BRE RS03020
gene id: 412418:BRE_RS03020
uniprot id: B5RPU4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

412418:BRE RS00130
gene id: 412418:BRE_RS00130
uniprot id: B5RQJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

412418:BRE RS01560
gene id: 412418:BRE_RS01560
uniprot id: B5RRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

412418:BRE RS03990
gene id: 412418:BRE_RS03990
uniprot id: B5RQC2
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

412418:BRE RS03140
gene id: 412418:BRE_RS03140
uniprot id: B5RPW3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

412418:BRE RS01315
gene id: 412418:BRE_RS01315
uniprot id: B5RR74
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

412418:BRE RS02205
gene id: 412418:BRE_RS02205
uniprot id: B5RRN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

412418:BRE RS00520
gene id: 412418:BRE_RS00520
uniprot id: B5RQS4
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

412418:BRE RS03790
gene id: 412418:BRE_RS03790
uniprot id: B5RQ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

412418:BRE RS02475
gene id: 412418:BRE_RS02475
uniprot id: B5RPI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

412418:BRE RS03170
gene id: 412418:BRE_RS03170
uniprot id: B5RPW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

412418:BRE RS02030
gene id: 412418:BRE_RS02030
uniprot id: B5RRK9
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS02430
gene id: 412418:BRE_RS02430
uniprot id: B5RPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

412418:BRE RS05140
gene id: 412418:BRE_RS05140
uniprot id: B5RS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the variable small protein (Vsp) family.
messages: Cell outer membrane
messages: Membrane
messages: The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

412418:BRE RS01280
gene id: 412418:BRE_RS01280
uniprot id: B5RR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

412418:BRE RS02310
gene id: 412418:BRE_RS02310
uniprot id: B5RRR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

412418:BRE RS02165
gene id: 412418:BRE_RS02165
uniprot id: B5RRN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

412418:BRE RS01915
gene id: 412418:BRE_RS01915
uniprot id: B5RRI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

412418:BRE RS01255
gene id: 412418:BRE_RS01255
uniprot id: B5RR63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

412418:BRE RS03315
gene id: 412418:BRE_RS03315
uniprot id: B5RPZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

412418:BRE RS01455
gene id: 412418:BRE_RS01455
uniprot id: B5RR99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

412418:BRE RS00650
gene id: 412418:BRE_RS00650
uniprot id: B5RQU8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

412418:BRE RS02180
gene id: 412418:BRE_RS02180
uniprot id: B5RRN5
names: Similarity
messages: Belongs to the IMPACT family.

412418:BRE RS01820
gene id: 412418:BRE_RS01820
uniprot id: B5RRH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

412418:BRE RS00770
gene id: 412418:BRE_RS00770
uniprot id: B5RQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial flagellin family.
messages: Component of the core of the flagella.
messages: Periplasm
messages: Periplasmic flagellum

412418:BRE RS03250
gene id: 412418:BRE_RS03250
uniprot id: B5RPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

412418:BRE RS01785
gene id: 412418:BRE_RS01785
uniprot id: B5RRG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

412418:BRE RS03305
gene id: 412418:BRE_RS03305
uniprot id: B5RPZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

412418:BRE RS02845
gene id: 412418:BRE_RS02845
uniprot id: B5RPR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

412418:BRE RS03275
gene id: 412418:BRE_RS03275
uniprot id: B5RPY7
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS03700
gene id: 412418:BRE_RS03700
uniprot id: B5RQ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

412418:BRE RS02505
gene id: 412418:BRE_RS02505
uniprot id: B5RPJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

412418:BRE RS03535
gene id: 412418:BRE_RS03535
uniprot id: B5RQ38
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

412418:BRE RS00080
gene id: 412418:BRE_RS00080
uniprot id: B5RQI7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

412418:BRE RS01000
gene id: 412418:BRE_RS01000
uniprot id: B5RR18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

412418:BRE RS04500
gene id: 412418:BRE_RS04500
uniprot id: B5RRV9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

412418:BRE RS02470
gene id: 412418:BRE_RS02470
uniprot id: B5RPI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

412418:BRE RS04155
gene id: 412418:BRE_RS04155
uniprot id: B5RQF2
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

412418:BRE RS00990
gene id: 412418:BRE_RS00990
uniprot id: B5RR16
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

412418:BRE RS02230
gene id: 412418:BRE_RS02230
uniprot id: B5RRP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

412418:BRE RS03350
gene id: 412418:BRE_RS03350
uniprot id: B5RQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

412418:BRE RS02535
gene id: 412418:BRE_RS02535
uniprot id: B5RPK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

412418:BRE RS01780
gene id: 412418:BRE_RS01780
uniprot id: B5RRG2
names: Similarity
messages: Belongs to the pyruvate kinase family.

412418:BRE RS00610
gene id: 412418:BRE_RS00610
uniprot id: B5RQU1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

412418:BRE RS00360
gene id: 412418:BRE_RS00360
uniprot id: B5RQP3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

412418:BRE RS03130
gene id: 412418:BRE_RS03130
uniprot id: B5RPW1
names: Subcellular Location Annotation
messages: Membrane

412418:BRE RS02355
gene id: 412418:BRE_RS02355
uniprot id: B5RRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

412418:BRE RS04290
gene id: 412418:BRE_RS04290
uniprot id: B5RQH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

412418:BRE RS02805
gene id: 412418:BRE_RS02805
uniprot id: B5RPQ2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.