404380:GBEM RS09445
gene id: 404380:GBEM_RS09445
uniprot id: B5EB36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

404380:GBEM RS18130
gene id: 404380:GBEM_RS18130
uniprot id: B5ED06
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS00865
gene id: 404380:GBEM_RS00865
uniprot id: B5E966
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS13590
gene id: 404380:GBEM_RS13590
uniprot id: B5EHS8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

404380:GBEM RS12630
gene id: 404380:GBEM_RS12630
uniprot id: B5EGQ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS09170
gene id: 404380:GBEM_RS09170
uniprot id: B5EAY1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

404380:GBEM RS07220
gene id: 404380:GBEM_RS07220
uniprot id: B5E7R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

404380:GBEM RS16380
gene id: 404380:GBEM_RS16380
uniprot id: B5EAE2
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

404380:GBEM RS09850
gene id: 404380:GBEM_RS09850
uniprot id: B5EBV9
names: Subcellular Location Annotation
messages: Periplasm

404380:GBEM RS05120
gene id: 404380:GBEM_RS05120
uniprot id: B5EGH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

404380:GBEM RS11845
gene id: 404380:GBEM_RS11845
uniprot id: B5EF67
names: Similarity
messages: Belongs to the MlaA family.

404380:GBEM RS15515
gene id: 404380:GBEM_RS15515
uniprot id: B5E8U3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

404380:GBEM RS02150
gene id: 404380:GBEM_RS02150
uniprot id: B5EBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

404380:GBEM RS01765
gene id: 404380:GBEM_RS01765
uniprot id: B5EAS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

404380:GBEM RS04515
gene id: 404380:GBEM_RS04515
uniprot id: B5EFM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS01180
gene id: 404380:GBEM_RS01180
uniprot id: B5E9W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

404380:GBEM RS04340
gene id: 404380:GBEM_RS04340
uniprot id: B5EEZ9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

404380:GBEM RS18840
gene id: 404380:GBEM_RS18840
uniprot id: B5EEI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

404380:GBEM RS04165
gene id: 404380:GBEM_RS04165
uniprot id: B5EEW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

404380:GBEM RS15785
gene id: 404380:GBEM_RS15785
uniprot id: B5E8Z8
names: Similarity
messages: Belongs to the YkuD family.

404380:GBEM RS01775
gene id: 404380:GBEM_RS01775
uniprot id: B5EAT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS08990
gene id: 404380:GBEM_RS08990
uniprot id: B5EAA1
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS02335
gene id: 404380:GBEM_RS02335
uniprot id: B5EBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS05240
gene id: 404380:GBEM_RS05240
uniprot id: B5EGJ8
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

404380:GBEM RS15635
gene id: 404380:GBEM_RS15635
uniprot id: B5E8W8
names: Similarity
messages: Belongs to the HypD family.

404380:GBEM RS09160
gene id: 404380:GBEM_RS09160
uniprot id: B5EAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS15905
gene id: 404380:GBEM_RS15905
uniprot id: B5E9L2
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS12230
gene id: 404380:GBEM_RS12230
uniprot id: B5EFZ0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

404380:GBEM RS08975
gene id: 404380:GBEM_RS08975
uniprot id: B5EA98
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS01210
gene id: 404380:GBEM_RS01210
uniprot id: B5E9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

404380:GBEM RS01535
gene id: 404380:GBEM_RS01535
uniprot id: B5EAM8
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

404380:GBEM RS08720
gene id: 404380:GBEM_RS08720
uniprot id: B5EA47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

404380:GBEM RS00820
gene id: 404380:GBEM_RS00820
uniprot id: B5E957
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

404380:GBEM RS01040
gene id: 404380:GBEM_RS01040
uniprot id: B5E9A2
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS12055
gene id: 404380:GBEM_RS12055
uniprot id: B5EFV6
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

404380:GBEM RS01205
gene id: 404380:GBEM_RS01205
uniprot id: B5E9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

404380:GBEM RS11875
gene id: 404380:GBEM_RS11875
uniprot id: B5EF75
names: Similarity
messages: Belongs to the universal stress protein A family.

404380:GBEM RS09535
gene id: 404380:GBEM_RS09535
uniprot id: B5EB54
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

404380:GBEM RS19165
gene id: 404380:GBEM_RS19165
uniprot id: B5EEP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

404380:GBEM RS09515
gene id: 404380:GBEM_RS09515
uniprot id: B5EB50
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

404380:GBEM RS12635
gene id: 404380:GBEM_RS12635
uniprot id: B5EGQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

404380:GBEM RS05680
gene id: 404380:GBEM_RS05680
uniprot id: B5EH50
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

404380:GBEM RS18890
gene id: 404380:GBEM_RS18890
uniprot id: B5EEJ0
names: Similarity
messages: Belongs to the UPF0758 family.

404380:GBEM RS10985
gene id: 404380:GBEM_RS10985
uniprot id: B5EDL0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

404380:GBEM RS17290
gene id: 404380:GBEM_RS17290
uniprot id: B5EC00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

404380:GBEM RS19570
gene id: 404380:GBEM_RS19570
uniprot id: B5EFF8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

404380:GBEM RS10875
gene id: 404380:GBEM_RS10875
uniprot id: B5EDI7
names: Similarity
messages: Belongs to the FrmR/RcnR family.

404380:GBEM RS12520
gene id: 404380:GBEM_RS12520
uniprot id: B5EGN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

404380:GBEM RS10300
gene id: 404380:GBEM_RS10300
uniprot id: B5ECN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

404380:GBEM RS02670
gene id: 404380:GBEM_RS02670
uniprot id: B5ECE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

404380:GBEM RS13415
gene id: 404380:GBEM_RS13415
uniprot id: B5EHF6
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS10245
gene id: 404380:GBEM_RS10245
uniprot id: B5ECM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

404380:GBEM RS00070
gene id: 404380:GBEM_RS00070
uniprot id: B5E7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS02340
gene id: 404380:GBEM_RS02340
uniprot id: B5EBN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

404380:GBEM RS19575
gene id: 404380:GBEM_RS19575
uniprot id: B5EFF9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

404380:GBEM RS04710
gene id: 404380:GBEM_RS04710
uniprot id: B5EFQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

404380:GBEM RS11130
gene id: 404380:GBEM_RS11130
uniprot id: B5EE89
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS02840
gene id: 404380:GBEM_RS02840
uniprot id: B5ECH3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

404380:GBEM RS10290
gene id: 404380:GBEM_RS10290
uniprot id: B5ECN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

404380:GBEM RS13200
gene id: 404380:GBEM_RS13200
uniprot id: B5EHB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS07290
gene id: 404380:GBEM_RS07290
uniprot id: B5E7T2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

404380:GBEM RS18080
gene id: 404380:GBEM_RS18080
uniprot id: B5ECZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS10870
gene id: 404380:GBEM_RS10870
uniprot id: B5EDI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

404380:GBEM RS00025
gene id: 404380:GBEM_RS00025
uniprot id: B5E7Q2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

404380:GBEM RS04655
gene id: 404380:GBEM_RS04655
uniprot id: B5EFP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

404380:GBEM RS17525
gene id: 404380:GBEM_RS17525
uniprot id: B5EC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

404380:GBEM RS09340
gene id: 404380:GBEM_RS09340
uniprot id: B5EB16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

404380:GBEM RS17540
gene id: 404380:GBEM_RS17540
uniprot id: B5EC50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

404380:GBEM RS14445
gene id: 404380:GBEM_RS14445
uniprot id: B5EIU2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

404380:GBEM RS01335
gene id: 404380:GBEM_RS01335
uniprot id: B5E9Z8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

404380:GBEM RS17565
gene id: 404380:GBEM_RS17565
uniprot id: B5EC55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

404380:GBEM RS13430
gene id: 404380:GBEM_RS13430
uniprot id: B5EHP6
names: Similarity
messages: Belongs to the YkuD family.

404380:GBEM RS18485
gene id: 404380:GBEM_RS18485
uniprot id: B5EDR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

404380:GBEM RS19315
gene id: 404380:GBEM_RS19315
uniprot id: B5EFA7
names: Similarity
messages: Belongs to the hemerythrin family.

404380:GBEM RS13730
gene id: 404380:GBEM_RS13730
uniprot id: B5EHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

404380:GBEM RS14190
gene id: 404380:GBEM_RS14190
uniprot id: B5EIE5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

404380:GBEM RS10860
gene id: 404380:GBEM_RS10860
uniprot id: B5EDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

404380:GBEM RS14875
gene id: 404380:GBEM_RS14875
uniprot id: B5E816
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

404380:GBEM RS09760
gene id: 404380:GBEM_RS09760
uniprot id: B5EBT9
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS17265
gene id: 404380:GBEM_RS17265
uniprot id: B5EBF9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

404380:GBEM RS19660
gene id: 404380:GBEM_RS19660
uniprot id: B5EFH6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

404380:GBEM RS18255
gene id: 404380:GBEM_RS18255
uniprot id: B5EDM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

404380:GBEM RS02430
gene id: 404380:GBEM_RS02430
uniprot id: B5EBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

404380:GBEM RS00970
gene id: 404380:GBEM_RS00970
uniprot id: B5E987
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

404380:GBEM RS05870
gene id: 404380:GBEM_RS05870
uniprot id: B5EHI0
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS15610
gene id: 404380:GBEM_RS15610
uniprot id: B5E8W3
names: Similarity
messages: Belongs to the histone deacetylase family.

404380:GBEM RS05040
gene id: 404380:GBEM_RS05040
uniprot id: B5EGG1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

404380:GBEM RS17615
gene id: 404380:GBEM_RS17615
uniprot id: B5EC65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

404380:GBEM RS13605
gene id: 404380:GBEM_RS13605
uniprot id: B5EHT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS13875
gene id: 404380:GBEM_RS13875
uniprot id: B5EHY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

404380:GBEM RS19560
gene id: 404380:GBEM_RS19560
uniprot id: B5EFF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

404380:GBEM RS02935
gene id: 404380:GBEM_RS02935
uniprot id: B5ED34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS07595
gene id: 404380:GBEM_RS07595
uniprot id: B5E7Z3
names: Similarity
messages: Belongs to the universal stress protein A family.

404380:GBEM RS06365
gene id: 404380:GBEM_RS06365
uniprot id: B5EI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS03595
gene id: 404380:GBEM_RS03595
uniprot id: B5EE15
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

404380:GBEM RS15880
gene id: 404380:GBEM_RS15880
uniprot id: B5E9K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

404380:GBEM RS12310
gene id: 404380:GBEM_RS12310
uniprot id: B5EG07
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

404380:GBEM RS04430
gene id: 404380:GBEM_RS04430
uniprot id: B5EFK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

404380:GBEM RS10105
gene id: 404380:GBEM_RS10105
uniprot id: B5ECJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS14430
gene id: 404380:GBEM_RS14430
uniprot id: B5EIT9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS08820
gene id: 404380:GBEM_RS08820
uniprot id: B5EA66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

404380:GBEM RS05945
gene id: 404380:GBEM_RS05945
uniprot id: B5EHJ5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

404380:GBEM RS08015
gene id: 404380:GBEM_RS08015
uniprot id: B5E8M8
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

404380:GBEM RS08115
gene id: 404380:GBEM_RS08115
uniprot id: B5E8P8
names: Similarity
messages: Belongs to the asparagine synthetase family.

404380:GBEM RS01185
gene id: 404380:GBEM_RS01185
uniprot id: B5E9W9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

404380:GBEM RS11930
gene id: 404380:GBEM_RS11930
uniprot id: B5EF86
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

404380:GBEM RS14165
gene id: 404380:GBEM_RS14165
uniprot id: B5EIE0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS09735
gene id: 404380:GBEM_RS09735
uniprot id: B5EBT4
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS11225
gene id: 404380:GBEM_RS11225
uniprot id: B5EEA8
names: Similarity
messages: Belongs to the hemerythrin family.

404380:GBEM RS18850
gene id: 404380:GBEM_RS18850
uniprot id: B5EEI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

404380:GBEM RS08525
gene id: 404380:GBEM_RS08525
uniprot id: B5E9H1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

404380:GBEM RS19405
gene id: 404380:GBEM_RS19405
uniprot id: B5EFC5
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

404380:GBEM RS10375
gene id: 404380:GBEM_RS10375
uniprot id: B5ECP8
names: Similarity
messages: Belongs to the cytochrome c-552 family.

404380:GBEM RS06970
gene id: 404380:GBEM_RS06970
uniprot id: B5EIP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS04665
gene id: 404380:GBEM_RS04665
uniprot id: B5EFQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

404380:GBEM RS15790
gene id: 404380:GBEM_RS15790
uniprot id: B5E8Z9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

404380:GBEM RS04765
gene id: 404380:GBEM_RS04765
uniprot id: B5EFS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

404380:GBEM RS06570
gene id: 404380:GBEM_RS06570
uniprot id: B5EI62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

404380:GBEM RS02035
gene id: 404380:GBEM_RS02035
uniprot id: B5EBH3
names: Similarity
messages: Belongs to the SUI1 family.

404380:GBEM RS04090
gene id: 404380:GBEM_RS04090
uniprot id: B5EEU9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

404380:GBEM RS00675
gene id: 404380:GBEM_RS00675
uniprot id: B5E927
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

404380:GBEM RS15685
gene id: 404380:GBEM_RS15685
uniprot id: B5E8X8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

404380:GBEM RS05010
gene id: 404380:GBEM_RS05010
uniprot id: B5EGF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

404380:GBEM RS04915
gene id: 404380:GBEM_RS04915
uniprot id: B5EGD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

404380:GBEM RS19725
gene id: 404380:GBEM_RS19725
uniprot id: B5EFI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

404380:GBEM RS11790
gene id: 404380:GBEM_RS11790
uniprot id: B5EF55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

404380:GBEM RS04720
gene id: 404380:GBEM_RS04720
uniprot id: B5EFR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

404380:GBEM RS04455
gene id: 404380:GBEM_RS04455
uniprot id: B5EFL3
names: Similarity
messages: Belongs to the peptidase C40 family.

404380:GBEM RS03345
gene id: 404380:GBEM_RS03345
uniprot id: B5EDB6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS12525
gene id: 404380:GBEM_RS12525
uniprot id: B5EGN2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

404380:GBEM RS14500
gene id: 404380:GBEM_RS14500
uniprot id: B5EIV3
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

404380:GBEM RS03535
gene id: 404380:GBEM_RS03535
uniprot id: B5EE03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

404380:GBEM RS04555
gene id: 404380:GBEM_RS04555
uniprot id: B5EFN3
names: Similarity
messages: Belongs to the YciI family.

404380:GBEM RS03195
gene id: 404380:GBEM_RS03195
uniprot id: B5ED87
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS07880
gene id: 404380:GBEM_RS07880
uniprot id: B5E8K1
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

404380:GBEM RS02835
gene id: 404380:GBEM_RS02835
uniprot id: B5ECH2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

404380:GBEM RS04635
gene id: 404380:GBEM_RS04635
uniprot id: B5EFP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

404380:GBEM RS15465
gene id: 404380:GBEM_RS15465
uniprot id: B5E8T3
names: Similarity
messages: Belongs to the pirin family.

404380:GBEM RS04475
gene id: 404380:GBEM_RS04475
uniprot id: B5EFL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

404380:GBEM RS03900
gene id: 404380:GBEM_RS03900
uniprot id: B5EER7
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

404380:GBEM RS09985
gene id: 404380:GBEM_RS09985
uniprot id: B5EBY5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

404380:GBEM RS18970
gene id: 404380:GBEM_RS18970
uniprot id: B5EEK6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS19640
gene id: 404380:GBEM_RS19640
uniprot id: B5EFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

404380:GBEM RS18525
gene id: 404380:GBEM_RS18525
uniprot id: B5EDS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

404380:GBEM RS09650
gene id: 404380:GBEM_RS09650
uniprot id: B5EBR6
names: Similarity
messages: Belongs to the YoeB family.

404380:GBEM RS01225
gene id: 404380:GBEM_RS01225
uniprot id: B5E9X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

404380:GBEM RS17245
gene id: 404380:GBEM_RS17245
uniprot id: B5EBF5
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS06185
gene id: 404380:GBEM_RS06185
uniprot id: B5EHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

404380:GBEM RS16775
gene id: 404380:GBEM_RS16775
uniprot id: B5EAL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

404380:GBEM RS18190
gene id: 404380:GBEM_RS18190
uniprot id: B5ED18
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

404380:GBEM RS04535
gene id: 404380:GBEM_RS04535
uniprot id: B5EFM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

404380:GBEM RS12295
gene id: 404380:GBEM_RS12295
uniprot id: B5EG04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

404380:GBEM RS07810
gene id: 404380:GBEM_RS07810
uniprot id: B5E8I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

404380:GBEM RS17670
gene id: 404380:GBEM_RS17670
uniprot id: B5EC76
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

404380:GBEM RS11610
gene id: 404380:GBEM_RS11610
uniprot id: B5EF23
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS04195
gene id: 404380:GBEM_RS04195
uniprot id: B5EEX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

404380:GBEM RS17105
gene id: 404380:GBEM_RS17105
uniprot id: B5EBC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

404380:GBEM RS18475
gene id: 404380:GBEM_RS18475
uniprot id: B5EDR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

404380:GBEM RS04330
gene id: 404380:GBEM_RS04330
uniprot id: B5EEZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

404380:GBEM RS11140
gene id: 404380:GBEM_RS11140
uniprot id: B5EE91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

404380:GBEM RS13405
gene id: 404380:GBEM_RS13405
uniprot id: B5EHF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

404380:GBEM RS06860
gene id: 404380:GBEM_RS06860
uniprot id: B5EIL9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

404380:GBEM RS19035
gene id: 404380:GBEM_RS19035
uniprot id: B5EEM0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

404380:GBEM RS02455
gene id: 404380:GBEM_RS02455
uniprot id: B5EBQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS08050
gene id: 404380:GBEM_RS08050
uniprot id: B5E8N5
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

404380:GBEM RS13195
gene id: 404380:GBEM_RS13195
uniprot id: B5EHB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS00745
gene id: 404380:GBEM_RS00745
uniprot id: B5E942
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

404380:GBEM RS18480
gene id: 404380:GBEM_RS18480
uniprot id: B5EDR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

404380:GBEM RS00890
gene id: 404380:GBEM_RS00890
uniprot id: B5E971
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

404380:GBEM RS04505
gene id: 404380:GBEM_RS04505
uniprot id: B5EFM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS18700
gene id: 404380:GBEM_RS18700
uniprot id: B5EDW0
names: Subcellular Location Annotation
messages: Secreted

404380:GBEM RS09400
gene id: 404380:GBEM_RS09400
uniprot id: B5EB27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

404380:GBEM RS01055
gene id: 404380:GBEM_RS01055
uniprot id: B5E9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

404380:GBEM RS17130
gene id: 404380:GBEM_RS17130
uniprot id: B5EBD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

404380:GBEM RS10410
gene id: 404380:GBEM_RS10410
uniprot id: B5ECQ5
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

404380:GBEM RS04745
gene id: 404380:GBEM_RS04745
uniprot id: B5EFR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

404380:GBEM RS01540
gene id: 404380:GBEM_RS01540
uniprot id: B5EAM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

404380:GBEM RS17825
gene id: 404380:GBEM_RS17825
uniprot id: B5ECU5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

404380:GBEM RS13695
gene id: 404380:GBEM_RS13695
uniprot id: B5EHU9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

404380:GBEM RS10770
gene id: 404380:GBEM_RS10770
uniprot id: B5EDG6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

404380:GBEM RS10395
gene id: 404380:GBEM_RS10395
uniprot id: B5ECQ2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

404380:GBEM RS03180
gene id: 404380:GBEM_RS03180
uniprot id: B5ED84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

404380:GBEM RS11865
gene id: 404380:GBEM_RS11865
uniprot id: B5EF72
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS17260
gene id: 404380:GBEM_RS17260
uniprot id: B5EBF8
names: Similarity
messages: Belongs to the GARS family.

404380:GBEM RS06310
gene id: 404380:GBEM_RS06310
uniprot id: B5EI12
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

404380:GBEM RS13580
gene id: 404380:GBEM_RS13580
uniprot id: B5EHS6
names: Similarity
messages: Belongs to the peptidase U62 family.

404380:GBEM RS07580
gene id: 404380:GBEM_RS07580
uniprot id: B5E7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS17015
gene id: 404380:GBEM_RS17015
uniprot id: B5EBA8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS00205
gene id: 404380:GBEM_RS00205
uniprot id: B5EJ45
names: Similarity
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS14125
gene id: 404380:GBEM_RS14125
uniprot id: B5EID2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

404380:GBEM RS15470
gene id: 404380:GBEM_RS15470
uniprot id: B5E8T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS00230
gene id: 404380:GBEM_RS00230
uniprot id: B5EJ50
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS06990
gene id: 404380:GBEM_RS06990
uniprot id: B5EIP5
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS20305
gene id: 404380:GBEM_RS20305
uniprot id: B5EES0
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS15030
gene id: 404380:GBEM_RS15030
uniprot id: B5E845
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

404380:GBEM RS05700
gene id: 404380:GBEM_RS05700
uniprot id: B5EH54
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS00080
gene id: 404380:GBEM_RS00080
uniprot id: B5E7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS06720
gene id: 404380:GBEM_RS06720
uniprot id: B5EIJ1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

404380:GBEM RS13720
gene id: 404380:GBEM_RS13720
uniprot id: B5EHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

404380:GBEM RS11480
gene id: 404380:GBEM_RS11480
uniprot id: B5EEG1
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

404380:GBEM RS12010
gene id: 404380:GBEM_RS12010
uniprot id: B5EFU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

404380:GBEM RS17855
gene id: 404380:GBEM_RS17855
uniprot id: B5ECV1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

404380:GBEM RS04830
gene id: 404380:GBEM_RS04830
uniprot id: B5EFT5
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

404380:GBEM RS08620
gene id: 404380:GBEM_RS08620
uniprot id: B5E9I9
names: Similarity
messages: Belongs to the UPF0235 family.

404380:GBEM RS11080
gene id: 404380:GBEM_RS11080
uniprot id: B5EE79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

404380:GBEM RS10390
gene id: 404380:GBEM_RS10390
uniprot id: B5ECQ1
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

404380:GBEM RS12000
gene id: 404380:GBEM_RS12000
uniprot id: B5EFU5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

404380:GBEM RS18675
gene id: 404380:GBEM_RS18675
uniprot id: B5EDV5
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

404380:GBEM RS07260
gene id: 404380:GBEM_RS07260
uniprot id: B5E7S6
names: Similarity
messages: Belongs to the AOR/FOR family.

404380:GBEM RS09670
gene id: 404380:GBEM_RS09670
uniprot id: B5EBS0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

404380:GBEM RS03530
gene id: 404380:GBEM_RS03530
uniprot id: B5EE02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

404380:GBEM RS09920
gene id: 404380:GBEM_RS09920
uniprot id: B5EBX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

404380:GBEM RS18160
gene id: 404380:GBEM_RS18160
uniprot id: B5ED12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

404380:GBEM RS06215
gene id: 404380:GBEM_RS06215
uniprot id: B5EHZ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

404380:GBEM RS17505
gene id: 404380:GBEM_RS17505
uniprot id: B5EC43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

404380:GBEM RS12465
gene id: 404380:GBEM_RS12465
uniprot id: B5EGM0
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS10575
gene id: 404380:GBEM_RS10575
uniprot id: B5EDC8
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

404380:GBEM RS12970
gene id: 404380:GBEM_RS12970
uniprot id: B5EH70
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS13080
gene id: 404380:GBEM_RS13080
uniprot id: B5EH92
names: Similarity
messages: Belongs to the AOR/FOR family.

404380:GBEM RS02210
gene id: 404380:GBEM_RS02210
uniprot id: B5EBK8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

404380:GBEM RS02290
gene id: 404380:GBEM_RS02290
uniprot id: B5EBM5
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

404380:GBEM RS00010
gene id: 404380:GBEM_RS00010
uniprot id: B5E7P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

404380:GBEM RS11855
gene id: 404380:GBEM_RS11855
uniprot id: B5EF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

404380:GBEM RS19255
gene id: 404380:GBEM_RS19255
uniprot id: B5EF95
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS05825
gene id: 404380:GBEM_RS05825
uniprot id: B5EHH0
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS18495
gene id: 404380:GBEM_RS18495
uniprot id: B5EDS0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

404380:GBEM RS11395
gene id: 404380:GBEM_RS11395
uniprot id: B5EEE3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

404380:GBEM RS15015
gene id: 404380:GBEM_RS15015
uniprot id: B5E842
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

404380:GBEM RS11110
gene id: 404380:GBEM_RS11110
uniprot id: B5EE85
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

404380:GBEM RS03470
gene id: 404380:GBEM_RS03470
uniprot id: B5EDZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

404380:GBEM RS18785
gene id: 404380:GBEM_RS18785
uniprot id: B5EEG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

404380:GBEM RS15045
gene id: 404380:GBEM_RS15045
uniprot id: B5E848
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS02760
gene id: 404380:GBEM_RS02760
uniprot id: B5ECF9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

404380:GBEM RS00420
gene id: 404380:GBEM_RS00420
uniprot id: B5E8D3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

404380:GBEM RS13255
gene id: 404380:GBEM_RS13255
uniprot id: B5EHC6
names: Similarity
messages: Belongs to the TlyA family.

404380:GBEM RS02470
gene id: 404380:GBEM_RS02470
uniprot id: B5ECA1
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

404380:GBEM RS16660
gene id: 404380:GBEM_RS16660
uniprot id: B5EAJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

404380:GBEM RS09970
gene id: 404380:GBEM_RS09970
uniprot id: B5EBY2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

404380:GBEM RS08625
gene id: 404380:GBEM_RS08625
uniprot id: B5E9J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

404380:GBEM RS14060
gene id: 404380:GBEM_RS14060
uniprot id: B5EIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

404380:GBEM RS18465
gene id: 404380:GBEM_RS18465
uniprot id: B5EDR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

404380:GBEM RS11555
gene id: 404380:GBEM_RS11555
uniprot id: B5EF12
names: Similarity
messages: Belongs to the Nth/MutY family.

404380:GBEM RS14050
gene id: 404380:GBEM_RS14050
uniprot id: B5EIB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

404380:GBEM RS18990
gene id: 404380:GBEM_RS18990
uniprot id: B5EEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

404380:GBEM RS07965
gene id: 404380:GBEM_RS07965
uniprot id: B5E8L8
names: Similarity
messages: Belongs to the cytochrome c family. PetJ subfamily.

404380:GBEM RS08265
gene id: 404380:GBEM_RS08265
uniprot id: B5E9C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

404380:GBEM RS13280
gene id: 404380:GBEM_RS13280
uniprot id: B5EHD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

404380:GBEM RS03825
gene id: 404380:GBEM_RS03825
uniprot id: B5EE60
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS11370
gene id: 404380:GBEM_RS11370
uniprot id: B5EED9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

404380:GBEM RS03140
gene id: 404380:GBEM_RS03140
uniprot id: B5ED76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

404380:GBEM RS01310
gene id: 404380:GBEM_RS01310
uniprot id: B5E9Z3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

404380:GBEM RS13855
gene id: 404380:GBEM_RS13855
uniprot id: B5EHY0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

404380:GBEM RS00225
gene id: 404380:GBEM_RS00225
uniprot id: B5EJ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS16025
gene id: 404380:GBEM_RS16025
uniprot id: B5E9N5
names: Similarity
messages: Belongs to the RutC family.

404380:GBEM RS00875
gene id: 404380:GBEM_RS00875
uniprot id: B5E968
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

404380:GBEM RS11500
gene id: 404380:GBEM_RS11500
uniprot id: B5EEG5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

404380:GBEM RS13750
gene id: 404380:GBEM_RS13750
uniprot id: B5EHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

404380:GBEM RS14025
gene id: 404380:GBEM_RS14025
uniprot id: B5EIB1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

404380:GBEM RS19305
gene id: 404380:GBEM_RS19305
uniprot id: B5EFA5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

404380:GBEM RS04615
gene id: 404380:GBEM_RS04615
uniprot id: B5EFP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

404380:GBEM RS10710
gene id: 404380:GBEM_RS10710
uniprot id: B5EDF5
names: Similarity
messages: Belongs to the creatininase superfamily.

404380:GBEM RS19450
gene id: 404380:GBEM_RS19450
uniprot id: B5EFD4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

404380:GBEM RS11315
gene id: 404380:GBEM_RS11315
uniprot id: B5EEC8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

404380:GBEM RS04450
gene id: 404380:GBEM_RS04450
uniprot id: B5EFL2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

404380:GBEM RS11615
gene id: 404380:GBEM_RS11615
uniprot id: B5EF24
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

404380:GBEM RS03700
gene id: 404380:GBEM_RS03700
uniprot id: B5EE36
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

404380:GBEM RS12975
gene id: 404380:GBEM_RS12975
uniprot id: B5EH71
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

404380:GBEM RS13170
gene id: 404380:GBEM_RS13170
uniprot id: B5EHA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

404380:GBEM RS19735
gene id: 404380:GBEM_RS19735
uniprot id: B5EFJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

404380:GBEM RS19710
gene id: 404380:GBEM_RS19710
uniprot id: B5EFI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

404380:GBEM RS08270
gene id: 404380:GBEM_RS08270
uniprot id: B5E9C2
names: Similarity
messages: Belongs to the peptidase S41A family.

404380:GBEM RS17850
gene id: 404380:GBEM_RS17850
uniprot id: B5ECV0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

404380:GBEM RS19785
gene id: 404380:GBEM_RS19785
uniprot id: B5EG43
names: Similarity
messages: Belongs to the phosphohexose mutase family.

404380:GBEM RS16310
gene id: 404380:GBEM_RS16310
uniprot id: B5E9U3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

404380:GBEM RS11440
gene id: 404380:GBEM_RS11440
uniprot id: B5EEF3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

404380:GBEM RS07250
gene id: 404380:GBEM_RS07250
uniprot id: B5E7S4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

404380:GBEM RS15100
gene id: 404380:GBEM_RS15100
uniprot id: B5E858
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

404380:GBEM RS00775
gene id: 404380:GBEM_RS00775
uniprot id: B5E948
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

404380:GBEM RS09815
gene id: 404380:GBEM_RS09815
uniprot id: B5EBV2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

404380:GBEM RS16450
gene id: 404380:GBEM_RS16450
uniprot id: B5EAF5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS00860
gene id: 404380:GBEM_RS00860
uniprot id: B5E965
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS01730
gene id: 404380:GBEM_RS01730
uniprot id: B5EAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

404380:GBEM RS12115
gene id: 404380:GBEM_RS12115
uniprot id: B5EFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

404380:GBEM RS13435
gene id: 404380:GBEM_RS13435
uniprot id: B5EHP7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

404380:GBEM RS00320
gene id: 404380:GBEM_RS00320
uniprot id: B5E8B2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS18410
gene id: 404380:GBEM_RS18410
uniprot id: B5EDQ3
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

404380:GBEM RS09695
gene id: 404380:GBEM_RS09695
uniprot id: B5EBS5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS16470
gene id: 404380:GBEM_RS16470
uniprot id: B5EAF9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

404380:GBEM RS16670
gene id: 404380:GBEM_RS16670
uniprot id: B5EAJ7
names: Similarity
messages: Belongs to the AOR/FOR family.

404380:GBEM RS09975
gene id: 404380:GBEM_RS09975
uniprot id: B5EBY3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

404380:GBEM RS19795
gene id: 404380:GBEM_RS19795
uniprot id: B5EG45
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS09840
gene id: 404380:GBEM_RS09840
uniprot id: B5EBV7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

404380:GBEM RS16535
gene id: 404380:GBEM_RS16535
uniprot id: B5EAH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

404380:GBEM RS03945
gene id: 404380:GBEM_RS03945
uniprot id: B5EES5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS10775
gene id: 404380:GBEM_RS10775
uniprot id: B5EDG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS11695
gene id: 404380:GBEM_RS11695
uniprot id: B5EF40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS14700
gene id: 404380:GBEM_RS14700
uniprot id: B5EIZ2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS02000
gene id: 404380:GBEM_RS02000
uniprot id: B5EBG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

404380:GBEM RS18880
gene id: 404380:GBEM_RS18880
uniprot id: B5EEI8
names: Similarity
messages: Belongs to the UPF0111 family.

404380:GBEM RS19580
gene id: 404380:GBEM_RS19580
uniprot id: B5EFG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS03395
gene id: 404380:GBEM_RS03395
uniprot id: B5EDX5
names: Similarity
messages: Belongs to the peptidase M16 family.

404380:GBEM RS06385
gene id: 404380:GBEM_RS06385
uniprot id: B5EI28
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

404380:GBEM RS16295
gene id: 404380:GBEM_RS16295
uniprot id: B5E9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

404380:GBEM RS18295
gene id: 404380:GBEM_RS18295
uniprot id: B5EDN0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

404380:GBEM RS12205
gene id: 404380:GBEM_RS12205
uniprot id: B5EFY5
names: Similarity
messages: Belongs to the peptidase U62 family.

404380:GBEM RS03000
gene id: 404380:GBEM_RS03000
uniprot id: B5ED47
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

404380:GBEM RS08195
gene id: 404380:GBEM_RS08195
uniprot id: B5E9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS18755
gene id: 404380:GBEM_RS18755
uniprot id: B5EDX1
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

404380:GBEM RS17710
gene id: 404380:GBEM_RS17710
uniprot id: B5EC84
names: Similarity
messages: Belongs to the peptidase M16 family.

404380:GBEM RS19550
gene id: 404380:GBEM_RS19550
uniprot id: B5EFF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS04910
gene id: 404380:GBEM_RS04910
uniprot id: B5EGD4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

404380:GBEM RS16545
gene id: 404380:GBEM_RS16545
uniprot id: B5EAH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

404380:GBEM RS07045
gene id: 404380:GBEM_RS07045
uniprot id: B5EIQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

404380:GBEM RS13230
gene id: 404380:GBEM_RS13230
uniprot id: B5EHC1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

404380:GBEM RS04795
gene id: 404380:GBEM_RS04795
uniprot id: B5EFS7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

404380:GBEM RS08380
gene id: 404380:GBEM_RS08380
uniprot id: B5E9E3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS17520
gene id: 404380:GBEM_RS17520
uniprot id: B5EC46
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

404380:GBEM RS08600
gene id: 404380:GBEM_RS08600
uniprot id: B5E9I5
names: Similarity
messages: Belongs to the RutC family.

404380:GBEM RS17140
gene id: 404380:GBEM_RS17140
uniprot id: B5EBD3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

404380:GBEM RS11995
gene id: 404380:GBEM_RS11995
uniprot id: B5EFU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

404380:GBEM RS12985
gene id: 404380:GBEM_RS12985
uniprot id: B5EH73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

404380:GBEM RS01870
gene id: 404380:GBEM_RS01870
uniprot id: B5EAV0
names: Similarity
messages: Belongs to the peptidase A31 family.

404380:GBEM RS00295
gene id: 404380:GBEM_RS00295
uniprot id: B5EJ63
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

404380:GBEM RS00825
gene id: 404380:GBEM_RS00825
uniprot id: B5E958
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS10275
gene id: 404380:GBEM_RS10275
uniprot id: B5ECM8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

404380:GBEM RS12015
gene id: 404380:GBEM_RS12015
uniprot id: B5EFU8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

404380:GBEM RS01700
gene id: 404380:GBEM_RS01700
uniprot id: B5EAR5
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

404380:GBEM RS03590
gene id: 404380:GBEM_RS03590
uniprot id: B5EE14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS18140
gene id: 404380:GBEM_RS18140
uniprot id: B5ED08
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

404380:GBEM RS00565
gene id: 404380:GBEM_RS00565
uniprot id: B5E8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

404380:GBEM RS09870
gene id: 404380:GBEM_RS09870
uniprot id: B5EBW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

404380:GBEM RS06820
gene id: 404380:GBEM_RS06820
uniprot id: B5EIL1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

404380:GBEM RS14555
gene id: 404380:GBEM_RS14555
uniprot id: B5EIW4
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

404380:GBEM RS13445
gene id: 404380:GBEM_RS13445
uniprot id: B5EHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

404380:GBEM RS13135
gene id: 404380:GBEM_RS13135
uniprot id: B5EHA2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS13735
gene id: 404380:GBEM_RS13735
uniprot id: B5EHV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

404380:GBEM RS16035
gene id: 404380:GBEM_RS16035
uniprot id: B5E9N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

404380:GBEM RS17700
gene id: 404380:GBEM_RS17700
uniprot id: B5EC82
names: Similarity
messages: Belongs to the CobH/CbiC family.

404380:GBEM RS03065
gene id: 404380:GBEM_RS03065
uniprot id: B5ED60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

404380:GBEM RS05270
gene id: 404380:GBEM_RS05270
uniprot id: B5EGK5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

404380:GBEM RS00855
gene id: 404380:GBEM_RS00855
uniprot id: B5E964
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS09415
gene id: 404380:GBEM_RS09415
uniprot id: B5EB30
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

404380:GBEM RS10210
gene id: 404380:GBEM_RS10210
uniprot id: B5ECL5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

404380:GBEM RS05375
gene id: 404380:GBEM_RS05375
uniprot id: B5EGY8
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS09395
gene id: 404380:GBEM_RS09395
uniprot id: B5EB26
names: Similarity
messages: Belongs to the transglycosylase Slt family.

404380:GBEM RS16515
gene id: 404380:GBEM_RS16515
uniprot id: B5EAG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

404380:GBEM RS13805
gene id: 404380:GBEM_RS13805
uniprot id: B5EHX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

404380:GBEM RS05860
gene id: 404380:GBEM_RS05860
uniprot id: B5EHH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

404380:GBEM RS08515
gene id: 404380:GBEM_RS08515
uniprot id: B5E9G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

404380:GBEM RS04625
gene id: 404380:GBEM_RS04625
uniprot id: B5EFP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

404380:GBEM RS00530
gene id: 404380:GBEM_RS00530
uniprot id: B5E8F6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

404380:GBEM RS06875
gene id: 404380:GBEM_RS06875
uniprot id: B5EIM2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

404380:GBEM RS03190
gene id: 404380:GBEM_RS03190
uniprot id: B5ED86
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

404380:GBEM RS01290
gene id: 404380:GBEM_RS01290
uniprot id: B5E9Z0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS06900
gene id: 404380:GBEM_RS06900
uniprot id: B5EIM7
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

404380:GBEM RS16010
gene id: 404380:GBEM_RS16010
uniprot id: B5E9N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

404380:GBEM RS01610
gene id: 404380:GBEM_RS01610
uniprot id: B5EAP5
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12510
gene id: 404380:GBEM_RS12510
uniprot id: B5EGM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS01800
gene id: 404380:GBEM_RS01800
uniprot id: B5EAT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

404380:GBEM RS07855
gene id: 404380:GBEM_RS07855
uniprot id: B5E8J6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

404380:GBEM RS04650
gene id: 404380:GBEM_RS04650
uniprot id: B5EFP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

404380:GBEM RS19545
gene id: 404380:GBEM_RS19545
uniprot id: B5EFF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS09495
gene id: 404380:GBEM_RS09495
uniprot id: B5EB46
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

404380:GBEM RS01565
gene id: 404380:GBEM_RS01565
uniprot id: B5EAN4
names: Similarity
messages: Belongs to the AOR/FOR family.

404380:GBEM RS01955
gene id: 404380:GBEM_RS01955
uniprot id: B5EAW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

404380:GBEM RS02965
gene id: 404380:GBEM_RS02965
uniprot id: B5ED40
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

404380:GBEM RS08320
gene id: 404380:GBEM_RS08320
uniprot id: B5E9D1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

404380:GBEM RS17610
gene id: 404380:GBEM_RS17610
uniprot id: B5EC64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

404380:GBEM RS18220
gene id: 404380:GBEM_RS18220
uniprot id: B5ED24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

404380:GBEM RS12505
gene id: 404380:GBEM_RS12505
uniprot id: B5EGM8
names: Similarity
messages: Belongs to the MT-A70-like family.

404380:GBEM RS07325
gene id: 404380:GBEM_RS07325
uniprot id: B5E7T9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

404380:GBEM RS12160
gene id: 404380:GBEM_RS12160
uniprot id: B5EFX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

404380:GBEM RS04780
gene id: 404380:GBEM_RS04780
uniprot id: B5EFS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

404380:GBEM RS18055
gene id: 404380:GBEM_RS18055
uniprot id: B5ECZ1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

404380:GBEM RS07195
gene id: 404380:GBEM_RS07195
uniprot id: B5EIT4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

404380:GBEM RS06935
gene id: 404380:GBEM_RS06935
uniprot id: B5EIN4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

404380:GBEM RS12880
gene id: 404380:GBEM_RS12880
uniprot id: B5EGV5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

404380:GBEM RS06615
gene id: 404380:GBEM_RS06615
uniprot id: B5EI72
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

404380:GBEM RS18115
gene id: 404380:GBEM_RS18115
uniprot id: B5ED03
names: Similarity
messages: Belongs to the CinA family.

404380:GBEM RS01375
gene id: 404380:GBEM_RS01375
uniprot id: B5EA06
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

404380:GBEM RS01045
gene id: 404380:GBEM_RS01045
uniprot id: B5E9A3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

404380:GBEM RS00235
gene id: 404380:GBEM_RS00235
uniprot id: B5EJ51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

404380:GBEM RS11030
gene id: 404380:GBEM_RS11030
uniprot id: B5EDL9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS18265
gene id: 404380:GBEM_RS18265
uniprot id: B5EDM4
names: Similarity
messages: Belongs to the FeoA family.

404380:GBEM RS19230
gene id: 404380:GBEM_RS19230
uniprot id: B5EEQ9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

404380:GBEM RS05130
gene id: 404380:GBEM_RS05130
uniprot id: B5EGH5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

404380:GBEM RS12415
gene id: 404380:GBEM_RS12415
uniprot id: B5EG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

404380:GBEM RS02540
gene id: 404380:GBEM_RS02540
uniprot id: B5ECB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

404380:GBEM RS00085
gene id: 404380:GBEM_RS00085
uniprot id: B5E7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

404380:GBEM RS06775
gene id: 404380:GBEM_RS06775
uniprot id: B5EIK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

404380:GBEM RS07370
gene id: 404380:GBEM_RS07370
uniprot id: B5E7U9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

404380:GBEM RS02620
gene id: 404380:GBEM_RS02620
uniprot id: B5ECD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transport of potassium into the cell.

404380:GBEM RS04065
gene id: 404380:GBEM_RS04065
uniprot id: B5EEU4
names: Similarity
messages: Belongs to the disproportionating enzyme family.

404380:GBEM RS08660
gene id: 404380:GBEM_RS08660
uniprot id: B5EA35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

404380:GBEM RS13740
gene id: 404380:GBEM_RS13740
uniprot id: B5EHV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

404380:GBEM RS14280
gene id: 404380:GBEM_RS14280
uniprot id: B5EIG3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

404380:GBEM RS04705
gene id: 404380:GBEM_RS04705
uniprot id: B5EFQ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

404380:GBEM RS00670
gene id: 404380:GBEM_RS00670
uniprot id: B5E926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

404380:GBEM RS10025
gene id: 404380:GBEM_RS10025
uniprot id: B5EBZ2
names: Similarity
messages: Belongs to the ros/MucR family.

404380:GBEM RS14150
gene id: 404380:GBEM_RS14150
uniprot id: B5EID7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

404380:GBEM RS00945
gene id: 404380:GBEM_RS00945
uniprot id: B5E982
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

404380:GBEM RS06455
gene id: 404380:GBEM_RS06455
uniprot id: B5EI39
names: Similarity
messages: Belongs to the bacterial secretin family.

404380:GBEM RS13410
gene id: 404380:GBEM_RS13410
uniprot id: B5EHF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

404380:GBEM RS03835
gene id: 404380:GBEM_RS03835
uniprot id: B5EE62
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

404380:GBEM RS02480
gene id: 404380:GBEM_RS02480
uniprot id: B5ECA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

404380:GBEM RS13745
gene id: 404380:GBEM_RS13745
uniprot id: B5EHV9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS01250
gene id: 404380:GBEM_RS01250
uniprot id: B5E9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

404380:GBEM RS01445
gene id: 404380:GBEM_RS01445
uniprot id: B5EA20
names: Similarity
messages: Belongs to the TPP enzyme family.

404380:GBEM RS02990
gene id: 404380:GBEM_RS02990
uniprot id: B5ED45
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

404380:GBEM RS19170
gene id: 404380:GBEM_RS19170
uniprot id: B5EEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

404380:GBEM RS18155
gene id: 404380:GBEM_RS18155
uniprot id: B5ED11
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

404380:GBEM RS06040
gene id: 404380:GBEM_RS06040
uniprot id: B5EHL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

404380:GBEM RS17510
gene id: 404380:GBEM_RS17510
uniprot id: B5EC44
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

404380:GBEM RS19390
gene id: 404380:GBEM_RS19390
uniprot id: B5EFC2
names: Subcellular Location Annotation
messages: Periplasm

404380:GBEM RS17210
gene id: 404380:GBEM_RS17210
uniprot id: B5EBE7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS00450
gene id: 404380:GBEM_RS00450
uniprot id: B5E8D9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS02270
gene id: 404380:GBEM_RS02270
uniprot id: B5EBM1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

404380:GBEM RS20265
gene id: 404380:GBEM_RS20265
uniprot id: B5EGY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

404380:GBEM RS07715
gene id: 404380:GBEM_RS07715
uniprot id: B5E8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

404380:GBEM RS19040
gene id: 404380:GBEM_RS19040
uniprot id: B5EEM1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

404380:GBEM RS02655
gene id: 404380:GBEM_RS02655
uniprot id: B5ECE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

404380:GBEM RS11830
gene id: 404380:GBEM_RS11830
uniprot id: B5EF64
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

404380:GBEM RS19485
gene id: 404380:GBEM_RS19485
uniprot id: B5EFE1
names: Similarity
messages: Belongs to the peptidase S66 family.

404380:GBEM RS01685
gene id: 404380:GBEM_RS01685
uniprot id: B5EAR2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

404380:GBEM RS18535
gene id: 404380:GBEM_RS18535
uniprot id: B5EDS8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

404380:GBEM RS04840
gene id: 404380:GBEM_RS04840
uniprot id: B5EFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS03740
gene id: 404380:GBEM_RS03740
uniprot id: B5EE44
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

404380:GBEM RS18730
gene id: 404380:GBEM_RS18730
uniprot id: B5EDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

404380:GBEM RS09845
gene id: 404380:GBEM_RS09845
uniprot id: B5EBV8
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

404380:GBEM RS18195
gene id: 404380:GBEM_RS18195
uniprot id: B5ED19
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

404380:GBEM RS19440
gene id: 404380:GBEM_RS19440
uniprot id: B5EFD2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS17570
gene id: 404380:GBEM_RS17570
uniprot id: B5EC56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

404380:GBEM RS04990
gene id: 404380:GBEM_RS04990
uniprot id: B5EGF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

404380:GBEM RS04750
gene id: 404380:GBEM_RS04750
uniprot id: B5EFR7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

404380:GBEM RS12570
gene id: 404380:GBEM_RS12570
uniprot id: B5EGP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

404380:GBEM RS07990
gene id: 404380:GBEM_RS07990
uniprot id: B5E8M3
names: Similarity
messages: Belongs to the FeoA family.

404380:GBEM RS04960
gene id: 404380:GBEM_RS04960
uniprot id: B5EGE4
names: Similarity
messages: Belongs to the archease family.

404380:GBEM RS09505
gene id: 404380:GBEM_RS09505
uniprot id: B5EB48
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

404380:GBEM RS03235
gene id: 404380:GBEM_RS03235
uniprot id: B5ED95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

404380:GBEM RS19595
gene id: 404380:GBEM_RS19595
uniprot id: B5EFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS19345
gene id: 404380:GBEM_RS19345
uniprot id: B5EFB3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS06780
gene id: 404380:GBEM_RS06780
uniprot id: B5EIK3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

404380:GBEM RS04755
gene id: 404380:GBEM_RS04755
uniprot id: B5EFR8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

404380:GBEM RS13840
gene id: 404380:GBEM_RS13840
uniprot id: B5EHX8
names: Similarity
messages: Belongs to the hemerythrin family.

404380:GBEM RS13010
gene id: 404380:GBEM_RS13010
uniprot id: B5EH78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

404380:GBEM RS06915
gene id: 404380:GBEM_RS06915
uniprot id: B5EIN0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

404380:GBEM RS18150
gene id: 404380:GBEM_RS18150
uniprot id: B5ED10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

404380:GBEM RS08415
gene id: 404380:GBEM_RS08415
uniprot id: B5E9F0
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS18430
gene id: 404380:GBEM_RS18430
uniprot id: B5EDQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

404380:GBEM RS02865
gene id: 404380:GBEM_RS02865
uniprot id: B5ECH8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

404380:GBEM RS17120
gene id: 404380:GBEM_RS17120
uniprot id: B5EBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

404380:GBEM RS10955
gene id: 404380:GBEM_RS10955
uniprot id: B5EDK4
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS01060
gene id: 404380:GBEM_RS01060
uniprot id: B5E9U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

404380:GBEM RS13225
gene id: 404380:GBEM_RS13225
uniprot id: B5EHC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

404380:GBEM RS04600
gene id: 404380:GBEM_RS04600
uniprot id: B5EFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

404380:GBEM RS02680
gene id: 404380:GBEM_RS02680
uniprot id: B5ECE6
names: Similarity
messages: Belongs to the arginase family.

404380:GBEM RS07200
gene id: 404380:GBEM_RS07200
uniprot id: B5E7R4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

404380:GBEM RS09205
gene id: 404380:GBEM_RS09205
uniprot id: B5EAY8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS15615
gene id: 404380:GBEM_RS15615
uniprot id: B5E8W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

404380:GBEM RS11095
gene id: 404380:GBEM_RS11095
uniprot id: B5EE82
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS01385
gene id: 404380:GBEM_RS01385
uniprot id: B5EA08
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

404380:GBEM RS19370
gene id: 404380:GBEM_RS19370
uniprot id: B5EFB8
names: Similarity
messages: Belongs to the peptidase A31 family.

404380:GBEM RS09450
gene id: 404380:GBEM_RS09450
uniprot id: B5EB37
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS16040
gene id: 404380:GBEM_RS16040
uniprot id: B5E9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

404380:GBEM RS19080
gene id: 404380:GBEM_RS19080
uniprot id: B5EEM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

404380:GBEM RS04675
gene id: 404380:GBEM_RS04675
uniprot id: B5EFQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

404380:GBEM RS12140
gene id: 404380:GBEM_RS12140
uniprot id: B5EFX3
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS13870
gene id: 404380:GBEM_RS13870
uniprot id: B5EHY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS10325
gene id: 404380:GBEM_RS10325
uniprot id: B5ECN8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

404380:GBEM RS04085
gene id: 404380:GBEM_RS04085
uniprot id: B5EEU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

404380:GBEM RS10890
gene id: 404380:GBEM_RS10890
uniprot id: B5EDJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

404380:GBEM RS00525
gene id: 404380:GBEM_RS00525
uniprot id: B5E8F5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

404380:GBEM RS08805
gene id: 404380:GBEM_RS08805
uniprot id: B5EA63
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

404380:GBEM RS00520
gene id: 404380:GBEM_RS00520
uniprot id: B5E8F4
names: Subcellular Location Annotation
messages: Secreted

404380:GBEM RS00250
gene id: 404380:GBEM_RS00250
uniprot id: B5EJ54
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

404380:GBEM RS16995
gene id: 404380:GBEM_RS16995
uniprot id: B5EBA5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

404380:GBEM RS18470
gene id: 404380:GBEM_RS18470
uniprot id: B5EDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

404380:GBEM RS09485
gene id: 404380:GBEM_RS09485
uniprot id: B5EB44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

404380:GBEM RS04800
gene id: 404380:GBEM_RS04800
uniprot id: B5EFS8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

404380:GBEM RS14440
gene id: 404380:GBEM_RS14440
uniprot id: B5EIU1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

404380:GBEM RS18725
gene id: 404380:GBEM_RS18725
uniprot id: B5EDW5
names: Similarity
messages: Belongs to the MotB family.

404380:GBEM RS19620
gene id: 404380:GBEM_RS19620
uniprot id: B5EFG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

404380:GBEM RS00445
gene id: 404380:GBEM_RS00445
uniprot id: B5E8D8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS07440
gene id: 404380:GBEM_RS07440
uniprot id: B5E7W4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS15670
gene id: 404380:GBEM_RS15670
uniprot id: B5E8X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

404380:GBEM RS03635
gene id: 404380:GBEM_RS03635
uniprot id: B5EE23
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

404380:GBEM RS15430
gene id: 404380:GBEM_RS15430
uniprot id: B5E8S6
names: Similarity
messages: Belongs to the ros/MucR family.

404380:GBEM RS05305
gene id: 404380:GBEM_RS05305
uniprot id: B5EGL1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS08325
gene id: 404380:GBEM_RS08325
uniprot id: B5E9D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

404380:GBEM RS09530
gene id: 404380:GBEM_RS09530
uniprot id: B5EB53
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS05760
gene id: 404380:GBEM_RS05760
uniprot id: B5EH65
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

404380:GBEM RS06485
gene id: 404380:GBEM_RS06485
uniprot id: B5EI45
names: Similarity
messages: Belongs to the peptidase S41A family.

404380:GBEM RS14710
gene id: 404380:GBEM_RS14710
uniprot id: B5EIZ4
names: Similarity
messages: Belongs to the cytochrome c-552 family.

404380:GBEM RS07275
gene id: 404380:GBEM_RS07275
uniprot id: B5E7S9
names: Similarity
messages: Belongs to the HdrA family.

404380:GBEM RS17070
gene id: 404380:GBEM_RS17070
uniprot id: B5EBB9
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

404380:GBEM RS06585
gene id: 404380:GBEM_RS06585
uniprot id: B5EI65
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

404380:GBEM RS02275
gene id: 404380:GBEM_RS02275
uniprot id: B5EBM2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS07130
gene id: 404380:GBEM_RS07130
uniprot id: B5EIS2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

404380:GBEM RS03865
gene id: 404380:GBEM_RS03865
uniprot id: B5EE68
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

404380:GBEM RS07955
gene id: 404380:GBEM_RS07955
uniprot id: B5E8L6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

404380:GBEM RS10660
gene id: 404380:GBEM_RS10660
uniprot id: B5EDE5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

404380:GBEM RS18095
gene id: 404380:GBEM_RS18095
uniprot id: B5ECZ9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

404380:GBEM RS06095
gene id: 404380:GBEM_RS06095
uniprot id: B5EHM2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS14690
gene id: 404380:GBEM_RS14690
uniprot id: B5EIZ0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS03255
gene id: 404380:GBEM_RS03255
uniprot id: B5ED99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

404380:GBEM RS12220
gene id: 404380:GBEM_RS12220
uniprot id: B5EFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

404380:GBEM RS08690
gene id: 404380:GBEM_RS08690
uniprot id: B5EA41
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

404380:GBEM RS09730
gene id: 404380:GBEM_RS09730
uniprot id: B5EBT3
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS06525
gene id: 404380:GBEM_RS06525
uniprot id: B5EI53
names: Similarity
messages: Belongs to the threonine synthase family.

404380:GBEM RS04730
gene id: 404380:GBEM_RS04730
uniprot id: B5EFR3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

404380:GBEM RS19225
gene id: 404380:GBEM_RS19225
uniprot id: B5EEQ8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS01710
gene id: 404380:GBEM_RS01710
uniprot id: B5EAR7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

404380:GBEM RS19680
gene id: 404380:GBEM_RS19680
uniprot id: B5EFI0
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

404380:GBEM RS09885
gene id: 404380:GBEM_RS09885
uniprot id: B5EBW6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

404380:GBEM RS05230
gene id: 404380:GBEM_RS05230
uniprot id: B5EGJ6
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS14130
gene id: 404380:GBEM_RS14130
uniprot id: B5EID3
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS01515
gene id: 404380:GBEM_RS01515
uniprot id: B5EAM4
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS02940
gene id: 404380:GBEM_RS02940
uniprot id: B5ED35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

404380:GBEM RS13510
gene id: 404380:GBEM_RS13510
uniprot id: B5EHR2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

404380:GBEM RS18855
gene id: 404380:GBEM_RS18855
uniprot id: B5EEI3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

404380:GBEM RS12980
gene id: 404380:GBEM_RS12980
uniprot id: B5EH72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

404380:GBEM RS06715
gene id: 404380:GBEM_RS06715
uniprot id: B5EIJ0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

404380:GBEM RS12960
gene id: 404380:GBEM_RS12960
uniprot id: B5EH68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

404380:GBEM RS16325
gene id: 404380:GBEM_RS16325
uniprot id: B5EAD1
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS11125
gene id: 404380:GBEM_RS11125
uniprot id: B5EE88
names: Similarity
messages: Belongs to the UPF0178 family.

404380:GBEM RS01545
gene id: 404380:GBEM_RS01545
uniprot id: B5EAN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS14515
gene id: 404380:GBEM_RS14515
uniprot id: B5EIV6
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS16760
gene id: 404380:GBEM_RS16760
uniprot id: B5EAL5
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS11605
gene id: 404380:GBEM_RS11605
uniprot id: B5EF22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS06015
gene id: 404380:GBEM_RS06015
uniprot id: B5EHK9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

404380:GBEM RS04480
gene id: 404380:GBEM_RS04480
uniprot id: B5EFL8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

404380:GBEM RS02125
gene id: 404380:GBEM_RS02125
uniprot id: B5EBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

404380:GBEM RS18800
gene id: 404380:GBEM_RS18800
uniprot id: B5EEH2
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

404380:GBEM RS01945
gene id: 404380:GBEM_RS01945
uniprot id: B5EAW5
names: Similarity
messages: Belongs to the GcvT family.

404380:GBEM RS00900
gene id: 404380:GBEM_RS00900
uniprot id: B5E973
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS04670
gene id: 404380:GBEM_RS04670
uniprot id: B5EFQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

404380:GBEM RS07210
gene id: 404380:GBEM_RS07210
uniprot id: B5E7R6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

404380:GBEM RS15095
gene id: 404380:GBEM_RS15095
uniprot id: B5E857
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

404380:GBEM RS11360
gene id: 404380:GBEM_RS11360
uniprot id: B5EED7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS19500
gene id: 404380:GBEM_RS19500
uniprot id: B5EFE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

404380:GBEM RS02450
gene id: 404380:GBEM_RS02450
uniprot id: B5EBQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

404380:GBEM RS02410
gene id: 404380:GBEM_RS02410
uniprot id: B5EBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

404380:GBEM RS01465
gene id: 404380:GBEM_RS01465
uniprot id: B5EA24
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

404380:GBEM RS16550
gene id: 404380:GBEM_RS16550
uniprot id: B5EAH4
names: Similarity
messages: Belongs to the DnaA family.

404380:GBEM RS19790
gene id: 404380:GBEM_RS19790
uniprot id: B5EG44
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

404380:GBEM RS00470
gene id: 404380:GBEM_RS00470
uniprot id: B5E8E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

404380:GBEM RS07675
gene id: 404380:GBEM_RS07675
uniprot id: B5E809
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

404380:GBEM RS18200
gene id: 404380:GBEM_RS18200
uniprot id: B5ED20
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

404380:GBEM RS17955
gene id: 404380:GBEM_RS17955
uniprot id: B5ECX1
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS19290
gene id: 404380:GBEM_RS19290
uniprot id: B5EFA2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS21040
gene id: 404380:GBEM_RS21040
uniprot id: B5EB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS02555
gene id: 404380:GBEM_RS02555
uniprot id: B5ECB8
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS02735
gene id: 404380:GBEM_RS02735
uniprot id: B5ECF4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

404380:GBEM RS19100
gene id: 404380:GBEM_RS19100
uniprot id: B5EEN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

404380:GBEM RS19615
gene id: 404380:GBEM_RS19615
uniprot id: B5EFG7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS15745
gene id: 404380:GBEM_RS15745
uniprot id: B5E8Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

404380:GBEM RS02220
gene id: 404380:GBEM_RS02220
uniprot id: B5EBL0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

404380:GBEM RS18435
gene id: 404380:GBEM_RS18435
uniprot id: B5EDQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

404380:GBEM RS18445
gene id: 404380:GBEM_RS18445
uniprot id: B5EDR0
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS09420
gene id: 404380:GBEM_RS09420
uniprot id: B5EB31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

404380:GBEM RS07435
gene id: 404380:GBEM_RS07435
uniprot id: B5E7W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

404380:GBEM RS06535
gene id: 404380:GBEM_RS06535
uniprot id: B5EI55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

404380:GBEM RS10030
gene id: 404380:GBEM_RS10030
uniprot id: B5EBZ3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

404380:GBEM RS07545
gene id: 404380:GBEM_RS07545
uniprot id: B5E7Y3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

404380:GBEM RS19415
gene id: 404380:GBEM_RS19415
uniprot id: B5EFC7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS16705
gene id: 404380:GBEM_RS16705
uniprot id: B5EAK4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

404380:GBEM RS08020
gene id: 404380:GBEM_RS08020
uniprot id: B5E8M9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

404380:GBEM RS19625
gene id: 404380:GBEM_RS19625
uniprot id: B5EFG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

404380:GBEM RS01830
gene id: 404380:GBEM_RS01830
uniprot id: B5EAU2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

404380:GBEM RS11860
gene id: 404380:GBEM_RS11860
uniprot id: B5EF71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

404380:GBEM RS00940
gene id: 404380:GBEM_RS00940
uniprot id: B5E981
names: Similarity
messages: Belongs to the DEAD box helicase family.

404380:GBEM RS09525
gene id: 404380:GBEM_RS09525
uniprot id: B5EB52
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

404380:GBEM RS14245
gene id: 404380:GBEM_RS14245
uniprot id: B5EIF6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS03930
gene id: 404380:GBEM_RS03930
uniprot id: B5EES2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

404380:GBEM RS07905
gene id: 404380:GBEM_RS07905
uniprot id: B5E8K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

404380:GBEM RS04215
gene id: 404380:GBEM_RS04215
uniprot id: B5EEX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

404380:GBEM RS08545
gene id: 404380:GBEM_RS08545
uniprot id: B5E9H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

404380:GBEM RS19160
gene id: 404380:GBEM_RS19160
uniprot id: B5EEP5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

404380:GBEM RS10330
gene id: 404380:GBEM_RS10330
uniprot id: B5ECN9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

404380:GBEM RS18110
gene id: 404380:GBEM_RS18110
uniprot id: B5ED02
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

404380:GBEM RS03715
gene id: 404380:GBEM_RS03715
uniprot id: B5EE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

404380:GBEM RS10880
gene id: 404380:GBEM_RS10880
uniprot id: B5EDI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

404380:GBEM RS15105
gene id: 404380:GBEM_RS15105
uniprot id: B5E859
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

404380:GBEM RS11265
gene id: 404380:GBEM_RS11265
uniprot id: B5EEB7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

404380:GBEM RS06370
gene id: 404380:GBEM_RS06370
uniprot id: B5EI25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

404380:GBEM RS08280
gene id: 404380:GBEM_RS08280
uniprot id: B5E9C4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

404380:GBEM RS03005
gene id: 404380:GBEM_RS03005
uniprot id: B5ED48
names: Similarity
messages: Belongs to the UPF0047 family.

404380:GBEM RS01115
gene id: 404380:GBEM_RS01115
uniprot id: B5E9V5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

404380:GBEM RS17975
gene id: 404380:GBEM_RS17975
uniprot id: B5ECX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

404380:GBEM RS00175
gene id: 404380:GBEM_RS00175
uniprot id: B5EJ39
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS13480
gene id: 404380:GBEM_RS13480
uniprot id: B5EHQ6
names: Similarity
messages: Belongs to the hemerythrin family.

404380:GBEM RS17100
gene id: 404380:GBEM_RS17100
uniprot id: B5EBC5
names: Similarity
messages: Belongs to the UPF0102 family.

404380:GBEM RS15445
gene id: 404380:GBEM_RS15445
uniprot id: B5E8S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

404380:GBEM RS02005
gene id: 404380:GBEM_RS02005
uniprot id: B5EBG7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

404380:GBEM RS06505
gene id: 404380:GBEM_RS06505
uniprot id: B5EI49
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

404380:GBEM RS15520
gene id: 404380:GBEM_RS15520
uniprot id: B5E8U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

404380:GBEM RS09855
gene id: 404380:GBEM_RS09855
uniprot id: B5EBW0
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

404380:GBEM RS14425
gene id: 404380:GBEM_RS14425
uniprot id: B5EIT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

404380:GBEM RS16720
gene id: 404380:GBEM_RS16720
uniprot id: B5EAK7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS19365
gene id: 404380:GBEM_RS19365
uniprot id: B5EFB7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS12050
gene id: 404380:GBEM_RS12050
uniprot id: B5EFV5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

404380:GBEM RS18455
gene id: 404380:GBEM_RS18455
uniprot id: B5EDR2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

404380:GBEM RS11545
gene id: 404380:GBEM_RS11545
uniprot id: B5EF10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS06515
gene id: 404380:GBEM_RS06515
uniprot id: B5EI51
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS15280
gene id: 404380:GBEM_RS15280
uniprot id: B5E893
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

404380:GBEM RS07860
gene id: 404380:GBEM_RS07860
uniprot id: B5E8J7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

404380:GBEM RS04965
gene id: 404380:GBEM_RS04965
uniprot id: B5EGE5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

404380:GBEM RS07610
gene id: 404380:GBEM_RS07610
uniprot id: B5E7Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

404380:GBEM RS07525
gene id: 404380:GBEM_RS07525
uniprot id: B5E7X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

404380:GBEM RS20225
gene id: 404380:GBEM_RS20225
uniprot id: B5EGX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

404380:GBEM RS07235
gene id: 404380:GBEM_RS07235
uniprot id: B5E7S1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

404380:GBEM RS18885
gene id: 404380:GBEM_RS18885
uniprot id: B5EEI9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS04520
gene id: 404380:GBEM_RS04520
uniprot id: B5EFM6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS15915
gene id: 404380:GBEM_RS15915
uniprot id: B5E9L4
names: Similarity
messages: Belongs to the FrhG family.

404380:GBEM RS13700
gene id: 404380:GBEM_RS13700
uniprot id: B5EHV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

404380:GBEM RS16880
gene id: 404380:GBEM_RS16880
uniprot id: B5EB86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

404380:GBEM RS17145
gene id: 404380:GBEM_RS17145
uniprot id: B5EBD4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

404380:GBEM RS02385
gene id: 404380:GBEM_RS02385
uniprot id: B5EBP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

404380:GBEM RS12275
gene id: 404380:GBEM_RS12275
uniprot id: B5EFZ9
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

404380:GBEM RS18125
gene id: 404380:GBEM_RS18125
uniprot id: B5ED05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

404380:GBEM RS09915
gene id: 404380:GBEM_RS09915
uniprot id: B5EBX2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

404380:GBEM RS20140
gene id: 404380:GBEM_RS20140
uniprot id: B5EGB1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

404380:GBEM RS18965
gene id: 404380:GBEM_RS18965
uniprot id: B5EEK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

404380:GBEM RS04785
gene id: 404380:GBEM_RS04785
uniprot id: B5EFS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

404380:GBEM RS12165
gene id: 404380:GBEM_RS12165
uniprot id: B5EFX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

404380:GBEM RS04095
gene id: 404380:GBEM_RS04095
uniprot id: B5EEV0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

404380:GBEM RS04445
gene id: 404380:GBEM_RS04445
uniprot id: B5EFL1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

404380:GBEM RS18225
gene id: 404380:GBEM_RS18225
uniprot id: B5ED25
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

404380:GBEM RS19535
gene id: 404380:GBEM_RS19535
uniprot id: B5EFF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

404380:GBEM RS06620
gene id: 404380:GBEM_RS06620
uniprot id: B5EI73
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS06530
gene id: 404380:GBEM_RS06530
uniprot id: B5EI54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

404380:GBEM RS18520
gene id: 404380:GBEM_RS18520
uniprot id: B5EDS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

404380:GBEM RS02730
gene id: 404380:GBEM_RS02730
uniprot id: B5ECF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

404380:GBEM RS09440
gene id: 404380:GBEM_RS09440
uniprot id: B5EB35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

404380:GBEM RS16625
gene id: 404380:GBEM_RS16625
uniprot id: B5EAI8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

404380:GBEM RS02945
gene id: 404380:GBEM_RS02945
uniprot id: B5ED36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

404380:GBEM RS14140
gene id: 404380:GBEM_RS14140
uniprot id: B5EID5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

404380:GBEM RS17545
gene id: 404380:GBEM_RS17545
uniprot id: B5EC51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

404380:GBEM RS18865
gene id: 404380:GBEM_RS18865
uniprot id: B5EEI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

404380:GBEM RS05030
gene id: 404380:GBEM_RS05030
uniprot id: B5EGF9
names: Similarity
messages: Belongs to the peptidase C40 family.

404380:GBEM RS09215
gene id: 404380:GBEM_RS09215
uniprot id: B5EAZ0
names: Similarity
messages: Belongs to the bacterial secretin family.

404380:GBEM RS10930
gene id: 404380:GBEM_RS10930
uniprot id: B5EDJ9
names: Similarity
messages: Belongs to the cytochrome c family. PetJ subfamily.

404380:GBEM RS05235
gene id: 404380:GBEM_RS05235
uniprot id: B5EGJ7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

404380:GBEM RS20235
gene id: 404380:GBEM_RS20235
uniprot id: B5EGX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

404380:GBEM RS11650
gene id: 404380:GBEM_RS11650
uniprot id: B5EF31
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS16680
gene id: 404380:GBEM_RS16680
uniprot id: B5EAJ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS11325
gene id: 404380:GBEM_RS11325
uniprot id: B5EED0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

404380:GBEM RS10935
gene id: 404380:GBEM_RS10935
uniprot id: B5EDK0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

404380:GBEM RS10450
gene id: 404380:GBEM_RS10450
uniprot id: B5ECR3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

404380:GBEM RS04545
gene id: 404380:GBEM_RS04545
uniprot id: B5EFN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

404380:GBEM RS04645
gene id: 404380:GBEM_RS04645
uniprot id: B5EFP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

404380:GBEM RS06805
gene id: 404380:GBEM_RS06805
uniprot id: B5EIK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

404380:GBEM RS13025
gene id: 404380:GBEM_RS13025
uniprot id: B5EH81
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

404380:GBEM RS17550
gene id: 404380:GBEM_RS17550
uniprot id: B5EC52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

404380:GBEM RS09910
gene id: 404380:GBEM_RS09910
uniprot id: B5EBX1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

404380:GBEM RS12545
gene id: 404380:GBEM_RS12545
uniprot id: B5EGN6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

404380:GBEM RS01905
gene id: 404380:GBEM_RS01905
uniprot id: B5EAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

404380:GBEM RS12865
gene id: 404380:GBEM_RS12865
uniprot id: B5EGV2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

404380:GBEM RS03170
gene id: 404380:GBEM_RS03170
uniprot id: B5ED82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

404380:GBEM RS12385
gene id: 404380:GBEM_RS12385
uniprot id: B5EG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

404380:GBEM RS19720
gene id: 404380:GBEM_RS19720
uniprot id: B5EFI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

404380:GBEM RS16030
gene id: 404380:GBEM_RS16030
uniprot id: B5E9N6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

404380:GBEM RS04300
gene id: 404380:GBEM_RS04300
uniprot id: B5EEZ1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

404380:GBEM RS04585
gene id: 404380:GBEM_RS04585
uniprot id: B5EFN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

404380:GBEM RS18210
gene id: 404380:GBEM_RS18210
uniprot id: B5ED22
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

404380:GBEM RS11600
gene id: 404380:GBEM_RS11600
uniprot id: B5EF21
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

404380:GBEM RS03485
gene id: 404380:GBEM_RS03485
uniprot id: B5EDZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

404380:GBEM RS00045
gene id: 404380:GBEM_RS00045
uniprot id: B5E7Q4
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS07980
gene id: 404380:GBEM_RS07980
uniprot id: B5E8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

404380:GBEM RS01935
gene id: 404380:GBEM_RS01935
uniprot id: B5EAW3
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

404380:GBEM RS12120
gene id: 404380:GBEM_RS12120
uniprot id: B5EFW9
names: Similarity
messages: Belongs to the glycosyl hydrolase 100 family.

404380:GBEM RS11015
gene id: 404380:GBEM_RS11015
uniprot id: B5EDL6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

404380:GBEM RS14105
gene id: 404380:GBEM_RS14105
uniprot id: B5EIC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

404380:GBEM RS02045
gene id: 404380:GBEM_RS02045
uniprot id: B5EBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

404380:GBEM RS18750
gene id: 404380:GBEM_RS18750
uniprot id: B5EDX0
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

404380:GBEM RS20420
gene id: 404380:GBEM_RS20420
uniprot id: B5EGR2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS11105
gene id: 404380:GBEM_RS11105
uniprot id: B5EE84
names: Similarity
messages: Belongs to the ros/MucR family.

404380:GBEM RS16700
gene id: 404380:GBEM_RS16700
uniprot id: B5EAK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS10560
gene id: 404380:GBEM_RS10560
uniprot id: B5ECT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

404380:GBEM RS19980
gene id: 404380:GBEM_RS19980
uniprot id: B5EG80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

404380:GBEM RS00410
gene id: 404380:GBEM_RS00410
uniprot id: B5E8D1
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS08045
gene id: 404380:GBEM_RS08045
uniprot id: B5E8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

404380:GBEM RS07115
gene id: 404380:GBEM_RS07115
uniprot id: B5EIR9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

404380:GBEM RS07975
gene id: 404380:GBEM_RS07975
uniprot id: B5E8M0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS13975
gene id: 404380:GBEM_RS13975
uniprot id: B5EIA1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

404380:GBEM RS07695
gene id: 404380:GBEM_RS07695
uniprot id: B5E8G4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

404380:GBEM RS12995
gene id: 404380:GBEM_RS12995
uniprot id: B5EH75
names: Similarity
messages: Belongs to the heat shock protein 70 family.

404380:GBEM RS08925
gene id: 404380:GBEM_RS08925
uniprot id: B5EA88
names: Similarity
messages: Belongs to the asparagine synthetase family.

404380:GBEM RS16710
gene id: 404380:GBEM_RS16710
uniprot id: B5EAK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

404380:GBEM RS02435
gene id: 404380:GBEM_RS02435
uniprot id: B5EBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

404380:GBEM RS01475
gene id: 404380:GBEM_RS01475
uniprot id: B5EA26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

404380:GBEM RS02925
gene id: 404380:GBEM_RS02925
uniprot id: B5ED32
names: Similarity
messages: Belongs to the GSP I family.

404380:GBEM RS00100
gene id: 404380:GBEM_RS00100
uniprot id: B5E7Q0
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

404380:GBEM RS16315
gene id: 404380:GBEM_RS16315
uniprot id: B5EAC9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

404380:GBEM RS18860
gene id: 404380:GBEM_RS18860
uniprot id: B5EEI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

404380:GBEM RS02010
gene id: 404380:GBEM_RS02010
uniprot id: B5EBG8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

404380:GBEM RS02250
gene id: 404380:GBEM_RS02250
uniprot id: B5EBL7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

404380:GBEM RS11415
gene id: 404380:GBEM_RS11415
uniprot id: B5EEE7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

404380:GBEM RS18405
gene id: 404380:GBEM_RS18405
uniprot id: B5EDQ2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS15075
gene id: 404380:GBEM_RS15075
uniprot id: B5E853
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

404380:GBEM RS07700
gene id: 404380:GBEM_RS07700
uniprot id: B5E8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

404380:GBEM RS00630
gene id: 404380:GBEM_RS00630
uniprot id: B5E918
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

404380:GBEM RS09980
gene id: 404380:GBEM_RS09980
uniprot id: B5EBY4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

404380:GBEM RS15525
gene id: 404380:GBEM_RS15525
uniprot id: B5E8U5
names: Similarity
messages: Belongs to the fabD family.

404380:GBEM RS04420
gene id: 404380:GBEM_RS04420
uniprot id: B5EFK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

404380:GBEM RS18505
gene id: 404380:GBEM_RS18505
uniprot id: B5EDS2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

404380:GBEM RS03785
gene id: 404380:GBEM_RS03785
uniprot id: B5EE53
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

404380:GBEM RS12945
gene id: 404380:GBEM_RS12945
uniprot id: B5EGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

404380:GBEM RS02380
gene id: 404380:GBEM_RS02380
uniprot id: B5EBP2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

404380:GBEM RS13535
gene id: 404380:GBEM_RS13535
uniprot id: B5EHR7
names: Similarity
messages: Belongs to the DprA/Smf family.

404380:GBEM RS17790
gene id: 404380:GBEM_RS17790
uniprot id: B5ECT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

404380:GBEM RS15145
gene id: 404380:GBEM_RS15145
uniprot id: B5E868
names: Similarity
messages: Belongs to the VgrG protein family.

404380:GBEM RS08710
gene id: 404380:GBEM_RS08710
uniprot id: B5EA45
names: Similarity
messages: Belongs to the CmpA/NrtA family.

404380:GBEM RS04150
gene id: 404380:GBEM_RS04150
uniprot id: B5EEW1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

404380:GBEM RS19070
gene id: 404380:GBEM_RS19070
uniprot id: B5EEM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

404380:GBEM RS18260
gene id: 404380:GBEM_RS18260
uniprot id: B5EDM3
names: Similarity
messages: Belongs to the FeoA family.

404380:GBEM RS08910
gene id: 404380:GBEM_RS08910
uniprot id: B5EA85
names: Similarity
messages: Belongs to the FemABX family.

404380:GBEM RS13660
gene id: 404380:GBEM_RS13660
uniprot id: B5EHU2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

404380:GBEM RS19690
gene id: 404380:GBEM_RS19690
uniprot id: B5EFI2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

404380:GBEM RS15540
gene id: 404380:GBEM_RS15540
uniprot id: B5E8U8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

404380:GBEM RS16990
gene id: 404380:GBEM_RS16990
uniprot id: B5EBA4
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

404380:GBEM RS04640
gene id: 404380:GBEM_RS04640
uniprot id: B5EFP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

404380:GBEM RS17530
gene id: 404380:GBEM_RS17530
uniprot id: B5EC48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

404380:GBEM RS02810
gene id: 404380:GBEM_RS02810
uniprot id: B5ECG7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

404380:GBEM RS15535
gene id: 404380:GBEM_RS15535
uniprot id: B5E8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

404380:GBEM RS04905
gene id: 404380:GBEM_RS04905
uniprot id: B5EGD3
names: Similarity
messages: Belongs to the peptidase S11 family.

404380:GBEM RS06500
gene id: 404380:GBEM_RS06500
uniprot id: B5EI48
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

404380:GBEM RS00015
gene id: 404380:GBEM_RS00015
uniprot id: B5E7P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

404380:GBEM RS06980
gene id: 404380:GBEM_RS06980
uniprot id: B5EIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

404380:GBEM RS11460
gene id: 404380:GBEM_RS11460
uniprot id: B5EEF7
names: Similarity
messages: Belongs to the PhoH family.

404380:GBEM RS01345
gene id: 404380:GBEM_RS01345
uniprot id: B5EA00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

404380:GBEM RS06665
gene id: 404380:GBEM_RS06665
uniprot id: B5EI82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

404380:GBEM RS01725
gene id: 404380:GBEM_RS01725
uniprot id: B5EAS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

404380:GBEM RS15930
gene id: 404380:GBEM_RS15930
uniprot id: B5E9L7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS01130
gene id: 404380:GBEM_RS01130
uniprot id: B5E9V9
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

404380:GBEM RS18165
gene id: 404380:GBEM_RS18165
uniprot id: B5ED13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

404380:GBEM RS16570
gene id: 404380:GBEM_RS16570
uniprot id: B5EAH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

404380:GBEM RS12285
gene id: 404380:GBEM_RS12285
uniprot id: B5EG02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

404380:GBEM RS13795
gene id: 404380:GBEM_RS13795
uniprot id: B5EHW9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

404380:GBEM RS06740
gene id: 404380:GBEM_RS06740
uniprot id: B5EIJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

404380:GBEM RS13600
gene id: 404380:GBEM_RS13600
uniprot id: B5EHT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

404380:GBEM RS09715
gene id: 404380:GBEM_RS09715
uniprot id: B5EBT0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS05415
gene id: 404380:GBEM_RS05415
uniprot id: B5EGZ6
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS17635
gene id: 404380:GBEM_RS17635
uniprot id: B5EC69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS04530
gene id: 404380:GBEM_RS04530
uniprot id: B5EFM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

404380:GBEM RS11910
gene id: 404380:GBEM_RS11910
uniprot id: B5EF82
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS08505
gene id: 404380:GBEM_RS08505
uniprot id: B5E9G7
names: Similarity
messages: Belongs to the ModE family.

404380:GBEM RS03050
gene id: 404380:GBEM_RS03050
uniprot id: B5ED57
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

404380:GBEM RS11035
gene id: 404380:GBEM_RS11035
uniprot id: B5EE71
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

404380:GBEM RS04875
gene id: 404380:GBEM_RS04875
uniprot id: B5EGC7
names: Similarity
messages: Belongs to the YkuD family.

404380:GBEM RS11505
gene id: 404380:GBEM_RS11505
uniprot id: B5EEG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS02360
gene id: 404380:GBEM_RS02360
uniprot id: B5EBN8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

404380:GBEM RS03600
gene id: 404380:GBEM_RS03600
uniprot id: B5EE16
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS19110
gene id: 404380:GBEM_RS19110
uniprot id: B5EEN5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

404380:GBEM RS19090
gene id: 404380:GBEM_RS19090
uniprot id: B5EEN1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

404380:GBEM RS17240
gene id: 404380:GBEM_RS17240
uniprot id: B5EBF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

404380:GBEM RS09720
gene id: 404380:GBEM_RS09720
uniprot id: B5EBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

404380:GBEM RS13865
gene id: 404380:GBEM_RS13865
uniprot id: B5EHY2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

404380:GBEM RS12955
gene id: 404380:GBEM_RS12955
uniprot id: B5EH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

404380:GBEM RS03695
gene id: 404380:GBEM_RS03695
uniprot id: B5EE35
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

404380:GBEM RS08595
gene id: 404380:GBEM_RS08595
uniprot id: B5E9I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

404380:GBEM RS01950
gene id: 404380:GBEM_RS01950
uniprot id: B5EAW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

404380:GBEM RS11410
gene id: 404380:GBEM_RS11410
uniprot id: B5EEE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS17915
gene id: 404380:GBEM_RS17915
uniprot id: B5ECW3
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12380
gene id: 404380:GBEM_RS12380
uniprot id: B5EG21
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS16080
gene id: 404380:GBEM_RS16080
uniprot id: B5E9P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

404380:GBEM RS08725
gene id: 404380:GBEM_RS08725
uniprot id: B5EA48
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

404380:GBEM RS16970
gene id: 404380:GBEM_RS16970
uniprot id: B5EB99
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

404380:GBEM RS20380
gene id: 404380:GBEM_RS20380
uniprot id: B5EBQ9
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS02300
gene id: 404380:GBEM_RS02300
uniprot id: B5EBM7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS10415
gene id: 404380:GBEM_RS10415
uniprot id: B5ECQ6
names: Similarity
messages: Belongs to the NifX/NifY family.

404380:GBEM RS01885
gene id: 404380:GBEM_RS01885
uniprot id: B5EAV3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS15530
gene id: 404380:GBEM_RS15530
uniprot id: B5E8U6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

404380:GBEM RS12625
gene id: 404380:GBEM_RS12625
uniprot id: B5EGQ2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS08425
gene id: 404380:GBEM_RS08425
uniprot id: B5E9F2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

404380:GBEM RS02425
gene id: 404380:GBEM_RS02425
uniprot id: B5EBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

404380:GBEM RS17255
gene id: 404380:GBEM_RS17255
uniprot id: B5EBF7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

404380:GBEM RS04945
gene id: 404380:GBEM_RS04945
uniprot id: B5EGE1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

404380:GBEM RS11430
gene id: 404380:GBEM_RS11430
uniprot id: B5EEF0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS19555
gene id: 404380:GBEM_RS19555
uniprot id: B5EFF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS16690
gene id: 404380:GBEM_RS16690
uniprot id: B5EAK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

404380:GBEM RS19995
gene id: 404380:GBEM_RS19995
uniprot id: B5EG83
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

404380:GBEM RS04740
gene id: 404380:GBEM_RS04740
uniprot id: B5EFR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

404380:GBEM RS02445
gene id: 404380:GBEM_RS02445
uniprot id: B5EBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

404380:GBEM RS05360
gene id: 404380:GBEM_RS05360
uniprot id: B5EGY5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

404380:GBEM RS15510
gene id: 404380:GBEM_RS15510
uniprot id: B5E8U2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

404380:GBEM RS14340
gene id: 404380:GBEM_RS14340
uniprot id: B5EIH5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

404380:GBEM RS04660
gene id: 404380:GBEM_RS04660
uniprot id: B5EFP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

404380:GBEM RS04145
gene id: 404380:GBEM_RS04145
uniprot id: B5EEW0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

404380:GBEM RS04185
gene id: 404380:GBEM_RS04185
uniprot id: B5EEW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

404380:GBEM RS07225
gene id: 404380:GBEM_RS07225
uniprot id: B5E7R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

404380:GBEM RS04770
gene id: 404380:GBEM_RS04770
uniprot id: B5EFS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS16715
gene id: 404380:GBEM_RS16715
uniprot id: B5EAK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

404380:GBEM RS05075
gene id: 404380:GBEM_RS05075
uniprot id: B5EGG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS13020
gene id: 404380:GBEM_RS13020
uniprot id: B5EH80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

404380:GBEM RS19745
gene id: 404380:GBEM_RS19745
uniprot id: B5EFJ3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

404380:GBEM RS08810
gene id: 404380:GBEM_RS08810
uniprot id: B5EA64
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

404380:GBEM RS18900
gene id: 404380:GBEM_RS18900
uniprot id: B5EEJ2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

404380:GBEM RS11405
gene id: 404380:GBEM_RS11405
uniprot id: B5EEE5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

404380:GBEM RS00640
gene id: 404380:GBEM_RS00640
uniprot id: B5E920
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

404380:GBEM RS10705
gene id: 404380:GBEM_RS10705
uniprot id: B5EDF4
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12710
gene id: 404380:GBEM_RS12710
uniprot id: B5EGS0
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

404380:GBEM RS02440
gene id: 404380:GBEM_RS02440
uniprot id: B5EBQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

404380:GBEM RS17680
gene id: 404380:GBEM_RS17680
uniprot id: B5EC78
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

404380:GBEM RS11020
gene id: 404380:GBEM_RS11020
uniprot id: B5EDL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

404380:GBEM RS10850
gene id: 404380:GBEM_RS10850
uniprot id: B5EDI2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

404380:GBEM RS15810
gene id: 404380:GBEM_RS15810
uniprot id: B5E903
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS06380
gene id: 404380:GBEM_RS06380
uniprot id: B5EI27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

404380:GBEM RS05735
gene id: 404380:GBEM_RS05735
uniprot id: B5EH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

404380:GBEM RS17820
gene id: 404380:GBEM_RS17820
uniprot id: B5ECU4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

404380:GBEM RS09470
gene id: 404380:GBEM_RS09470
uniprot id: B5EB41
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

404380:GBEM RS02845
gene id: 404380:GBEM_RS02845
uniprot id: B5ECH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

404380:GBEM RS15965
gene id: 404380:GBEM_RS15965
uniprot id: B5E9M4
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS15080
gene id: 404380:GBEM_RS15080
uniprot id: B5E854
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

404380:GBEM RS00695
gene id: 404380:GBEM_RS00695
uniprot id: B5E931
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS17435
gene id: 404380:GBEM_RS17435
uniprot id: B5EC29
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

404380:GBEM RS13525
gene id: 404380:GBEM_RS13525
uniprot id: B5EHR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

404380:GBEM RS01990
gene id: 404380:GBEM_RS01990
uniprot id: B5EBG4
names: Similarity
messages: Belongs to the thioredoxin family.

404380:GBEM RS17135
gene id: 404380:GBEM_RS17135
uniprot id: B5EBD2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

404380:GBEM RS09520
gene id: 404380:GBEM_RS09520
uniprot id: B5EB51
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

404380:GBEM RS09825
gene id: 404380:GBEM_RS09825
uniprot id: B5EBV4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

404380:GBEM RS07660
gene id: 404380:GBEM_RS07660
uniprot id: B5E806
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS17065
gene id: 404380:GBEM_RS17065
uniprot id: B5EBB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

404380:GBEM RS12235
gene id: 404380:GBEM_RS12235
uniprot id: B5EFZ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS12620
gene id: 404380:GBEM_RS12620
uniprot id: B5EGQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

404380:GBEM RS06315
gene id: 404380:GBEM_RS06315
uniprot id: B5EI13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

404380:GBEM RS05140
gene id: 404380:GBEM_RS05140
uniprot id: B5EGH7
names: Similarity
messages: Belongs to the pirin family.

404380:GBEM RS18530
gene id: 404380:GBEM_RS18530
uniprot id: B5EDS7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS01485
gene id: 404380:GBEM_RS01485
uniprot id: B5EA28
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS18270
gene id: 404380:GBEM_RS18270
uniprot id: B5EDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

404380:GBEM RS02400
gene id: 404380:GBEM_RS02400
uniprot id: B5EBP6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS09200
gene id: 404380:GBEM_RS09200
uniprot id: B5EAY7
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS19105
gene id: 404380:GBEM_RS19105
uniprot id: B5EEN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

404380:GBEM RS11665
gene id: 404380:GBEM_RS11665
uniprot id: B5EF34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

404380:GBEM RS11220
gene id: 404380:GBEM_RS11220
uniprot id: B5EEA7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS13015
gene id: 404380:GBEM_RS13015
uniprot id: B5EH79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

404380:GBEM RS01705
gene id: 404380:GBEM_RS01705
uniprot id: B5EAR6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

404380:GBEM RS09660
gene id: 404380:GBEM_RS09660
uniprot id: B5EBR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

404380:GBEM RS04630
gene id: 404380:GBEM_RS04630
uniprot id: B5EFP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

404380:GBEM RS00375
gene id: 404380:GBEM_RS00375
uniprot id: B5E8C4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

404380:GBEM RS11765
gene id: 404380:GBEM_RS11765
uniprot id: B5EF50
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

404380:GBEM RS07050
gene id: 404380:GBEM_RS07050
uniprot id: B5EIQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

404380:GBEM RS00850
gene id: 404380:GBEM_RS00850
uniprot id: B5E963
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS10975
gene id: 404380:GBEM_RS10975
uniprot id: B5EDK8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

404380:GBEM RS06545
gene id: 404380:GBEM_RS06545
uniprot id: B5EI57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

404380:GBEM RS17500
gene id: 404380:GBEM_RS17500
uniprot id: B5EC42
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

404380:GBEM RS05925
gene id: 404380:GBEM_RS05925
uniprot id: B5EHJ1
names: Similarity
messages: Belongs to the pyruvate kinase family.

404380:GBEM RS14480
gene id: 404380:GBEM_RS14480
uniprot id: B5EIU9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

404380:GBEM RS06495
gene id: 404380:GBEM_RS06495
uniprot id: B5EI47
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

404380:GBEM RS18775
gene id: 404380:GBEM_RS18775
uniprot id: B5EEG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

404380:GBEM RS14580
gene id: 404380:GBEM_RS14580
uniprot id: B5EIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

404380:GBEM RS18065
gene id: 404380:GBEM_RS18065
uniprot id: B5ECZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

404380:GBEM RS00500
gene id: 404380:GBEM_RS00500
uniprot id: B5E8F0
names: Similarity
messages: Belongs to the UPF0502 family.

404380:GBEM RS06575
gene id: 404380:GBEM_RS06575
uniprot id: B5EI63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

404380:GBEM RS13970
gene id: 404380:GBEM_RS13970
uniprot id: B5EIA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

404380:GBEM RS17840
gene id: 404380:GBEM_RS17840
uniprot id: B5ECU8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

404380:GBEM RS06705
gene id: 404380:GBEM_RS06705
uniprot id: B5EII8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

404380:GBEM RS19905
gene id: 404380:GBEM_RS19905
uniprot id: B5EG65
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS16845
gene id: 404380:GBEM_RS16845
uniprot id: B5EB79
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

404380:GBEM RS18005
gene id: 404380:GBEM_RS18005
uniprot id: B5ECY1
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS00110
gene id: 404380:GBEM_RS00110
uniprot id: B5EJ27
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

404380:GBEM RS03405
gene id: 404380:GBEM_RS03405
uniprot id: B5EDX8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

404380:GBEM RS20025
gene id: 404380:GBEM_RS20025
uniprot id: B5EG89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

404380:GBEM RS17480
gene id: 404380:GBEM_RS17480
uniprot id: B5EC38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

404380:GBEM RS20610
gene id: 404380:GBEM_RS20610
uniprot id: B5EFS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

404380:GBEM RS13810
gene id: 404380:GBEM_RS13810
uniprot id: B5EHX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

404380:GBEM RS13765
gene id: 404380:GBEM_RS13765
uniprot id: B5EHW3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS16740
gene id: 404380:GBEM_RS16740
uniprot id: B5EAL1
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

404380:GBEM RS18395
gene id: 404380:GBEM_RS18395
uniprot id: B5EDQ0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

404380:GBEM RS12225
gene id: 404380:GBEM_RS12225
uniprot id: B5EFY9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

404380:GBEM RS05345
gene id: 404380:GBEM_RS05345
uniprot id: B5EGY2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

404380:GBEM RS02825
gene id: 404380:GBEM_RS02825
uniprot id: B5ECH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

404380:GBEM RS07465
gene id: 404380:GBEM_RS07465
uniprot id: B5E7W8
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12215
gene id: 404380:GBEM_RS12215
uniprot id: B5EFY7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

404380:GBEM RS02110
gene id: 404380:GBEM_RS02110
uniprot id: B5EBI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS15680
gene id: 404380:GBEM_RS15680
uniprot id: B5E8X7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

404380:GBEM RS11840
gene id: 404380:GBEM_RS11840
uniprot id: B5EF66
names: Similarity
messages: Belongs to the MlaA family.

404380:GBEM RS14260
gene id: 404380:GBEM_RS14260
uniprot id: B5EIF9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS10840
gene id: 404380:GBEM_RS10840
uniprot id: B5EDI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

404380:GBEM RS07315
gene id: 404380:GBEM_RS07315
uniprot id: B5E7T7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

404380:GBEM RS18740
gene id: 404380:GBEM_RS18740
uniprot id: B5EDW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

404380:GBEM RS05430
gene id: 404380:GBEM_RS05430
uniprot id: B5EGZ9
names: Similarity
messages: Belongs to the asparagine synthetase family.

404380:GBEM RS07845
gene id: 404380:GBEM_RS07845
uniprot id: B5E8J4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

404380:GBEM RS00950
gene id: 404380:GBEM_RS00950
uniprot id: B5E983
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

404380:GBEM RS20055
gene id: 404380:GBEM_RS20055
uniprot id: B5EG94
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

404380:GBEM RS16085
gene id: 404380:GBEM_RS16085
uniprot id: B5E9P8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

404380:GBEM RS09690
gene id: 404380:GBEM_RS09690
uniprot id: B5EBS4
names: Similarity
messages: Belongs to the leucine-binding protein family.

404380:GBEM RS04775
gene id: 404380:GBEM_RS04775
uniprot id: B5EFS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

404380:GBEM RS06930
gene id: 404380:GBEM_RS06930
uniprot id: B5EIN3
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

404380:GBEM RS07470
gene id: 404380:GBEM_RS07470
uniprot id: B5E7W9
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

404380:GBEM RS19270
gene id: 404380:GBEM_RS19270
uniprot id: B5EF98
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS13240
gene id: 404380:GBEM_RS13240
uniprot id: B5EHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

404380:GBEM RS20070
gene id: 404380:GBEM_RS20070
uniprot id: B5EG97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

404380:GBEM RS12585
gene id: 404380:GBEM_RS12585
uniprot id: B5EGP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

404380:GBEM RS04160
gene id: 404380:GBEM_RS04160
uniprot id: B5EEW3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS09965
gene id: 404380:GBEM_RS09965
uniprot id: B5EBY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

404380:GBEM RS01570
gene id: 404380:GBEM_RS01570
uniprot id: B5EAN5
names: Subunit
messages: Heterodimer of a large and a small subunit.

404380:GBEM RS07015
gene id: 404380:GBEM_RS07015
uniprot id: B5EIQ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS09125
gene id: 404380:GBEM_RS09125
uniprot id: B5EAC7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

404380:GBEM RS00485
gene id: 404380:GBEM_RS00485
uniprot id: B5E8E7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

404380:GBEM RS10490
gene id: 404380:GBEM_RS10490
uniprot id: B5ECS1
names: Similarity
messages: Belongs to the Skp family.

404380:GBEM RS19425
gene id: 404380:GBEM_RS19425
uniprot id: B5EFC9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

404380:GBEM RS11390
gene id: 404380:GBEM_RS11390
uniprot id: B5EEE2
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

404380:GBEM RS07535
gene id: 404380:GBEM_RS07535
uniprot id: B5E7Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

404380:GBEM RS15505
gene id: 404380:GBEM_RS15505
uniprot id: B5E8U1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

404380:GBEM RS19590
gene id: 404380:GBEM_RS19590
uniprot id: B5EFG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS18500
gene id: 404380:GBEM_RS18500
uniprot id: B5EDS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS03645
gene id: 404380:GBEM_RS03645
uniprot id: B5EE25
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

404380:GBEM RS11145
gene id: 404380:GBEM_RS11145
uniprot id: B5EE92
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS11295
gene id: 404380:GBEM_RS11295
uniprot id: B5EEC4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

404380:GBEM RS15375
gene id: 404380:GBEM_RS15375
uniprot id: B5E8R6
names: Similarity
messages: Belongs to the P(II) protein family.

404380:GBEM RS06165
gene id: 404380:GBEM_RS06165
uniprot id: B5EHN6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS00805
gene id: 404380:GBEM_RS00805
uniprot id: B5E954
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

404380:GBEM RS15855
gene id: 404380:GBEM_RS15855
uniprot id: B5E9K2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS14380
gene id: 404380:GBEM_RS14380
uniprot id: B5EII3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

404380:GBEM RS11400
gene id: 404380:GBEM_RS11400
uniprot id: B5EEE4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

404380:GBEM RS08655
gene id: 404380:GBEM_RS08655
uniprot id: B5E9J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

404380:GBEM RS07120
gene id: 404380:GBEM_RS07120
uniprot id: B5EIS0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

404380:GBEM RS16370
gene id: 404380:GBEM_RS16370
uniprot id: B5EAE0
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS16540
gene id: 404380:GBEM_RS16540
uniprot id: B5EAH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

404380:GBEM RS20300
gene id: 404380:GBEM_RS20300
uniprot id: B5EE59
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS00155
gene id: 404380:GBEM_RS00155
uniprot id: B5EJ35
names: Similarity
messages: Belongs to the HdrA family.

404380:GBEM RS00005
gene id: 404380:GBEM_RS00005
uniprot id: B5E7P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

404380:GBEM RS07345
gene id: 404380:GBEM_RS07345
uniprot id: B5E7U4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

404380:GBEM RS11800
gene id: 404380:GBEM_RS11800
uniprot id: B5EF57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

404380:GBEM RS07190
gene id: 404380:GBEM_RS07190
uniprot id: B5EIT3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

404380:GBEM RS00580
gene id: 404380:GBEM_RS00580
uniprot id: B5E8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

404380:GBEM RS12070
gene id: 404380:GBEM_RS12070
uniprot id: B5EFV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

404380:GBEM RS19065
gene id: 404380:GBEM_RS19065
uniprot id: B5EEM6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

404380:GBEM RS06595
gene id: 404380:GBEM_RS06595
uniprot id: B5EI68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm

404380:GBEM RS13530
gene id: 404380:GBEM_RS13530
uniprot id: B5EHR6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

404380:GBEM RS07125
gene id: 404380:GBEM_RS07125
uniprot id: B5EIS1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

404380:GBEM RS08025
gene id: 404380:GBEM_RS08025
uniprot id: B5E8N0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

404380:GBEM RS18780
gene id: 404380:GBEM_RS18780
uniprot id: B5EEG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

404380:GBEM RS11775
gene id: 404380:GBEM_RS11775
uniprot id: B5EF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS02850
gene id: 404380:GBEM_RS02850
uniprot id: B5ECH5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

404380:GBEM RS13705
gene id: 404380:GBEM_RS13705
uniprot id: B5EHV1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

404380:GBEM RS18845
gene id: 404380:GBEM_RS18845
uniprot id: B5EEI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

404380:GBEM RS11330
gene id: 404380:GBEM_RS11330
uniprot id: B5EED1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FdhD family.
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

404380:GBEM RS04735
gene id: 404380:GBEM_RS04735
uniprot id: B5EFR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

404380:GBEM RS02595
gene id: 404380:GBEM_RS02595
uniprot id: B5ECC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

404380:GBEM RS03015
gene id: 404380:GBEM_RS03015
uniprot id: B5ED50
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

404380:GBEM RS16530
gene id: 404380:GBEM_RS16530
uniprot id: B5EAH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

404380:GBEM RS11700
gene id: 404380:GBEM_RS11700
uniprot id: B5EF41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

404380:GBEM RS15070
gene id: 404380:GBEM_RS15070
uniprot id: B5E852
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

404380:GBEM RS05210
gene id: 404380:GBEM_RS05210
uniprot id: B5EGJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

404380:GBEM RS03100
gene id: 404380:GBEM_RS03100
uniprot id: B5ED67
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS03970
gene id: 404380:GBEM_RS03970
uniprot id: B5EET0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

404380:GBEM RS08535
gene id: 404380:GBEM_RS08535
uniprot id: B5E9H3
names: Similarity
messages: Belongs to the YjdM family.

404380:GBEM RS12020
gene id: 404380:GBEM_RS12020
uniprot id: B5EFU9
names: Similarity
messages: Belongs to the type III secretion exporter family.

404380:GBEM RS12085
gene id: 404380:GBEM_RS12085
uniprot id: B5EFW2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the epimerization of various hydrophobic dipeptides, such as L-Ala-L-Phe. Has epimerase activity with L-Ala-L-Thr, L-Ala-L-Met, L-Ala-L-Tyr, as well as L-Phe-L-Met, L-Phe-L-Ser and L-Phe-L-Thr (in vitro).
messages: Part of a large, functionally divergent protein family. Protein modeling and substrate docking was used to predict the substrate specificity, prior to biochemical analysis.

404380:GBEM RS07005
gene id: 404380:GBEM_RS07005
uniprot id: B5EIP8
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

404380:GBEM RS07875
gene id: 404380:GBEM_RS07875
uniprot id: B5E8K0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

404380:GBEM RS16975
gene id: 404380:GBEM_RS16975
uniprot id: B5EBA0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

404380:GBEM RS11465
gene id: 404380:GBEM_RS11465
uniprot id: B5EEF8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

404380:GBEM RS01350
gene id: 404380:GBEM_RS01350
uniprot id: B5EA01
names: Similarity
messages: Belongs to the peptidase M1 family.

404380:GBEM RS00135
gene id: 404380:GBEM_RS00135
uniprot id: B5EJ31
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

404380:GBEM RS07910
gene id: 404380:GBEM_RS07910
uniprot id: B5E8K7
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

404380:GBEM RS16230
gene id: 404380:GBEM_RS16230
uniprot id: B5E9S7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

404380:GBEM RS05085
gene id: 404380:GBEM_RS05085
uniprot id: B5EGH1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

404380:GBEM RS14210
gene id: 404380:GBEM_RS14210
uniprot id: B5EIE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

404380:GBEM RS02100
gene id: 404380:GBEM_RS02100
uniprot id: B5EBI6
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS01245
gene id: 404380:GBEM_RS01245
uniprot id: B5E9Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

404380:GBEM RS10305
gene id: 404380:GBEM_RS10305
uniprot id: B5ECN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

404380:GBEM RS10960
gene id: 404380:GBEM_RS10960
uniprot id: B5EDK5
names: Similarity
messages: Belongs to the leucine-binding protein family.

404380:GBEM RS01970
gene id: 404380:GBEM_RS01970
uniprot id: B5EAX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

404380:GBEM RS01215
gene id: 404380:GBEM_RS01215
uniprot id: B5E9X5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

404380:GBEM RS13265
gene id: 404380:GBEM_RS13265
uniprot id: B5EHC9
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS01330
gene id: 404380:GBEM_RS01330
uniprot id: B5E9Z7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

404380:GBEM RS07385
gene id: 404380:GBEM_RS07385
uniprot id: B5E7V2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

404380:GBEM RS19975
gene id: 404380:GBEM_RS19975
uniprot id: B5EG79
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

404380:GBEM RS11485
gene id: 404380:GBEM_RS11485
uniprot id: B5EEG2
names: Similarity
messages: Belongs to the MEMO1 family.

404380:GBEM RS07655
gene id: 404380:GBEM_RS07655
uniprot id: B5E805
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS01470
gene id: 404380:GBEM_RS01470
uniprot id: B5EA25
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS00935
gene id: 404380:GBEM_RS00935
uniprot id: B5E980
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

404380:GBEM RS03795
gene id: 404380:GBEM_RS03795
uniprot id: B5EE55
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

404380:GBEM RS16695
gene id: 404380:GBEM_RS16695
uniprot id: B5EAK2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

404380:GBEM RS19530
gene id: 404380:GBEM_RS19530
uniprot id: B5EFF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS06795
gene id: 404380:GBEM_RS06795
uniprot id: B5EIK6
names: Similarity
messages: Belongs to the AOR/FOR family.

404380:GBEM RS00715
gene id: 404380:GBEM_RS00715
uniprot id: B5E935
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

404380:GBEM RS11685
gene id: 404380:GBEM_RS11685
uniprot id: B5EF38
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12320
gene id: 404380:GBEM_RS12320
uniprot id: B5EG09
names: Similarity
messages: Belongs to the SfsA family.

404380:GBEM RS00845
gene id: 404380:GBEM_RS00845
uniprot id: B5E962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

404380:GBEM RS18640
gene id: 404380:GBEM_RS18640
uniprot id: B5EDU8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

404380:GBEM RS12155
gene id: 404380:GBEM_RS12155
uniprot id: B5EFX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

404380:GBEM RS17685
gene id: 404380:GBEM_RS17685
uniprot id: B5EC79
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

404380:GBEM RS15715
gene id: 404380:GBEM_RS15715
uniprot id: B5E8Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

404380:GBEM RS18105
gene id: 404380:GBEM_RS18105
uniprot id: B5ED01
names: Similarity
messages: Belongs to the LarC family.

404380:GBEM RS15215
gene id: 404380:GBEM_RS15215
uniprot id: B5E882
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

404380:GBEM RS06020
gene id: 404380:GBEM_RS06020
uniprot id: B5EHL0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

404380:GBEM RS00170
gene id: 404380:GBEM_RS00170
uniprot id: B5EJ38
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS15925
gene id: 404380:GBEM_RS15925
uniprot id: B5E9L6
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS07850
gene id: 404380:GBEM_RS07850
uniprot id: B5E8J5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

404380:GBEM RS06350
gene id: 404380:GBEM_RS06350
uniprot id: B5EI20
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

404380:GBEM RS13800
gene id: 404380:GBEM_RS13800
uniprot id: B5EHX0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

404380:GBEM RS01815
gene id: 404380:GBEM_RS01815
uniprot id: B5EAU0
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS05290
gene id: 404380:GBEM_RS05290
uniprot id: B5EGK8
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS05695
gene id: 404380:GBEM_RS05695
uniprot id: B5EH53
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

404380:GBEM RS16875
gene id: 404380:GBEM_RS16875
uniprot id: B5EB85
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS04325
gene id: 404380:GBEM_RS04325
uniprot id: B5EEZ6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

404380:GBEM RS07165
gene id: 404380:GBEM_RS07165
uniprot id: B5EIS9
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS07670
gene id: 404380:GBEM_RS07670
uniprot id: B5E808
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

404380:GBEM RS08155
gene id: 404380:GBEM_RS08155
uniprot id: B5E8Q6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

404380:GBEM RS02970
gene id: 404380:GBEM_RS02970
uniprot id: B5ED41
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

404380:GBEM RS19815
gene id: 404380:GBEM_RS19815
uniprot id: B5EG49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

404380:GBEM RS18310
gene id: 404380:GBEM_RS18310
uniprot id: B5EDN3
names: Similarity
messages: Belongs to the CapA family.

404380:GBEM RS13905
gene id: 404380:GBEM_RS13905
uniprot id: B5EHZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

404380:GBEM RS20230
gene id: 404380:GBEM_RS20230
uniprot id: B5EGX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

404380:GBEM RS01960
gene id: 404380:GBEM_RS01960
uniprot id: B5EAW8
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

404380:GBEM RS09805
gene id: 404380:GBEM_RS09805
uniprot id: B5EBV0
names: Similarity
messages: Belongs to the TrpF family.

404380:GBEM RS04700
gene id: 404380:GBEM_RS04700
uniprot id: B5EFQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

404380:GBEM RS19835
gene id: 404380:GBEM_RS19835
uniprot id: B5EG53
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

404380:GBEM RS10965
gene id: 404380:GBEM_RS10965
uniprot id: B5EDK6
names: Similarity
messages: Belongs to the leucine-binding protein family.

404380:GBEM RS04610
gene id: 404380:GBEM_RS04610
uniprot id: B5EFN9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

404380:GBEM RS06865
gene id: 404380:GBEM_RS06865
uniprot id: B5EIM0
names: Similarity
messages: Belongs to the YkuD family.

404380:GBEM RS08260
gene id: 404380:GBEM_RS08260
uniprot id: B5E9C0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

404380:GBEM RS06765
gene id: 404380:GBEM_RS06765
uniprot id: B5EIK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

404380:GBEM RS09955
gene id: 404380:GBEM_RS09955
uniprot id: B5EBX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS16105
gene id: 404380:GBEM_RS16105
uniprot id: B5E9Q4
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS05205
gene id: 404380:GBEM_RS05205
uniprot id: B5EGJ1
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12615
gene id: 404380:GBEM_RS12615
uniprot id: B5EGQ0
names: Similarity
messages: Belongs to the UPF0166 family.

404380:GBEM RS15035
gene id: 404380:GBEM_RS15035
uniprot id: B5E846
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

404380:GBEM RS19075
gene id: 404380:GBEM_RS19075
uniprot id: B5EEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

404380:GBEM RS16270
gene id: 404380:GBEM_RS16270
uniprot id: B5E9T5
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS13040
gene id: 404380:GBEM_RS13040
uniprot id: B5EH84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

404380:GBEM RS04265
gene id: 404380:GBEM_RS04265
uniprot id: B5EEY4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

404380:GBEM RS16400
gene id: 404380:GBEM_RS16400
uniprot id: B5EAE6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

404380:GBEM RS15665
gene id: 404380:GBEM_RS15665
uniprot id: B5E8X4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

404380:GBEM RS16245
gene id: 404380:GBEM_RS16245
uniprot id: B5E9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

404380:GBEM RS14560
gene id: 404380:GBEM_RS14560
uniprot id: B5EIW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS20220
gene id: 404380:GBEM_RS20220
uniprot id: B5EGX1
names: Similarity
messages: Belongs to the peptidase C56 family.

404380:GBEM RS17055
gene id: 404380:GBEM_RS17055
uniprot id: B5EBB6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

404380:GBEM RS12990
gene id: 404380:GBEM_RS12990
uniprot id: B5EH74
names: Similarity
messages: Belongs to the transglycosylase Slt family.

404380:GBEM RS19650
gene id: 404380:GBEM_RS19650
uniprot id: B5EFH4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

404380:GBEM RS09765
gene id: 404380:GBEM_RS09765
uniprot id: B5EBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

404380:GBEM RS05365
gene id: 404380:GBEM_RS05365
uniprot id: B5EGY6
names: Similarity
messages: Belongs to the FemABX family.

404380:GBEM RS08830
gene id: 404380:GBEM_RS08830
uniprot id: B5EA68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

404380:GBEM RS19715
gene id: 404380:GBEM_RS19715
uniprot id: B5EFI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

404380:GBEM RS07575
gene id: 404380:GBEM_RS07575
uniprot id: B5E7Y9
names: Similarity
messages: Belongs to the P(II) protein family.

404380:GBEM RS08055
gene id: 404380:GBEM_RS08055
uniprot id: B5E8N6
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

404380:GBEM RS18045
gene id: 404380:GBEM_RS18045
uniprot id: B5ECY9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS02285
gene id: 404380:GBEM_RS02285
uniprot id: B5EBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

404380:GBEM RS15660
gene id: 404380:GBEM_RS15660
uniprot id: B5E8X3
names: Similarity
messages: Belongs to the peptidase A31 family.

404380:GBEM RS17280
gene id: 404380:GBEM_RS17280
uniprot id: B5EBG2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

404380:GBEM RS20000
gene id: 404380:GBEM_RS20000
uniprot id: B5EG84
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS02230
gene id: 404380:GBEM_RS02230
uniprot id: B5EBL2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

404380:GBEM RS19030
gene id: 404380:GBEM_RS19030
uniprot id: B5EEL9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

404380:GBEM RS11380
gene id: 404380:GBEM_RS11380
uniprot id: B5EEE0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

404380:GBEM RS19025
gene id: 404380:GBEM_RS19025
uniprot id: B5EEL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

404380:GBEM RS01305
gene id: 404380:GBEM_RS01305
uniprot id: B5E9Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

404380:GBEM RS09390
gene id: 404380:GBEM_RS09390
uniprot id: B5EB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

404380:GBEM RS09290
gene id: 404380:GBEM_RS09290
uniprot id: B5EB05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

404380:GBEM RS15630
gene id: 404380:GBEM_RS15630
uniprot id: B5E8W7
names: Similarity
messages: Belongs to the HypE family.

404380:GBEM RS10280
gene id: 404380:GBEM_RS10280
uniprot id: B5ECM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS00350
gene id: 404380:GBEM_RS00350
uniprot id: B5E8B8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

404380:GBEM RS13185
gene id: 404380:GBEM_RS13185
uniprot id: B5EHB2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

404380:GBEM RS11920
gene id: 404380:GBEM_RS11920
uniprot id: B5EF84
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS05880
gene id: 404380:GBEM_RS05880
uniprot id: B5EHI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

404380:GBEM RS11795
gene id: 404380:GBEM_RS11795
uniprot id: B5EF56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

404380:GBEM RS02815
gene id: 404380:GBEM_RS02815
uniprot id: B5ECG8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

404380:GBEM RS01030
gene id: 404380:GBEM_RS01030
uniprot id: B5E9A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

404380:GBEM RS16125
gene id: 404380:GBEM_RS16125
uniprot id: B5E9Q7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

404380:GBEM RS01050
gene id: 404380:GBEM_RS01050
uniprot id: B5E9A4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

404380:GBEM RS00415
gene id: 404380:GBEM_RS00415
uniprot id: B5E8D2
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS08455
gene id: 404380:GBEM_RS08455
uniprot id: B5E9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

404380:GBEM RS17785
gene id: 404380:GBEM_RS17785
uniprot id: B5EC98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

404380:GBEM RS12490
gene id: 404380:GBEM_RS12490
uniprot id: B5EGM5
names: Similarity
names: Subunit
messages: Belongs to the organic radical-activating enzymes family.
messages: Monomer.

404380:GBEM RS01975
gene id: 404380:GBEM_RS01975
uniprot id: B5EAX1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

404380:GBEM RS03775
gene id: 404380:GBEM_RS03775
uniprot id: B5EE51
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

404380:GBEM RS04495
gene id: 404380:GBEM_RS04495
uniprot id: B5EFM1
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS06285
gene id: 404380:GBEM_RS06285
uniprot id: B5EI07
names: Similarity
messages: Belongs to the hemerythrin family.

404380:GBEM RS02390
gene id: 404380:GBEM_RS02390
uniprot id: B5EBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein.
messages: Membrane

404380:GBEM RS19155
gene id: 404380:GBEM_RS19155
uniprot id: B5EEP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

404380:GBEM RS10685
gene id: 404380:GBEM_RS10685
uniprot id: B5EDF0
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

404380:GBEM RS11705
gene id: 404380:GBEM_RS11705
uniprot id: B5EF42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

404380:GBEM RS14595
gene id: 404380:GBEM_RS14595
uniprot id: B5EIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

404380:GBEM RS16355
gene id: 404380:GBEM_RS16355
uniprot id: B5EAD7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS03460
gene id: 404380:GBEM_RS03460
uniprot id: B5EDY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

404380:GBEM RS00965
gene id: 404380:GBEM_RS00965
uniprot id: B5E986
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS16640
gene id: 404380:GBEM_RS16640
uniprot id: B5EAJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

404380:GBEM RS11385
gene id: 404380:GBEM_RS11385
uniprot id: B5EEE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

404380:GBEM RS06340
gene id: 404380:GBEM_RS06340
uniprot id: B5EI18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

404380:GBEM RS00035
gene id: 404380:GBEM_RS00035
uniprot id: B5E7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

404380:GBEM RS02980
gene id: 404380:GBEM_RS02980
uniprot id: B5ED43
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

404380:GBEM RS02315
gene id: 404380:GBEM_RS02315
uniprot id: B5EBN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

404380:GBEM RS06590
gene id: 404380:GBEM_RS06590
uniprot id: B5EI66
names: Similarity
messages: Belongs to the peptidase M29 family.

404380:GBEM RS08350
gene id: 404380:GBEM_RS08350
uniprot id: B5E9D7
names: Similarity
messages: Belongs to the universal stress protein A family.

404380:GBEM RS04180
gene id: 404380:GBEM_RS04180
uniprot id: B5EEW7
names: Similarity
messages: Belongs to the Skp family.

404380:GBEM RS07790
gene id: 404380:GBEM_RS07790
uniprot id: B5E8I3
names: Similarity
messages: Belongs to the bacterial secretin family.

404380:GBEM RS01795
gene id: 404380:GBEM_RS01795
uniprot id: B5EAT4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

404380:GBEM RS03315
gene id: 404380:GBEM_RS03315
uniprot id: B5EDB0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS15450
gene id: 404380:GBEM_RS15450
uniprot id: B5E8T0
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS10700
gene id: 404380:GBEM_RS10700
uniprot id: B5EDF3
names: Similarity
messages: Belongs to the CvfB family.

404380:GBEM RS10285
gene id: 404380:GBEM_RS10285
uniprot id: B5ECN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS07885
gene id: 404380:GBEM_RS07885
uniprot id: B5E8K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

404380:GBEM RS00240
gene id: 404380:GBEM_RS00240
uniprot id: B5EJ52
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12400
gene id: 404380:GBEM_RS12400
uniprot id: B5EG25
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS17495
gene id: 404380:GBEM_RS17495
uniprot id: B5EC41
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

404380:GBEM RS07380
gene id: 404380:GBEM_RS07380
uniprot id: B5E7V1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

404380:GBEM RS17650
gene id: 404380:GBEM_RS17650
uniprot id: B5EC72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS15935
gene id: 404380:GBEM_RS15935
uniprot id: B5E9L8
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS07500
gene id: 404380:GBEM_RS07500
uniprot id: B5E7X4
names: Similarity
messages: Belongs to the YggT family.

404380:GBEM RS13755
gene id: 404380:GBEM_RS13755
uniprot id: B5EHW1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

404380:GBEM RS18460
gene id: 404380:GBEM_RS18460
uniprot id: B5EDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

404380:GBEM RS11270
gene id: 404380:GBEM_RS11270
uniprot id: B5EEB8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

404380:GBEM RS00200
gene id: 404380:GBEM_RS00200
uniprot id: B5EJ44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

404380:GBEM RS12950
gene id: 404380:GBEM_RS12950
uniprot id: B5EGW9
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS15825
gene id: 404380:GBEM_RS15825
uniprot id: B5E906
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

404380:GBEM RS14115
gene id: 404380:GBEM_RS14115
uniprot id: B5EID0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

404380:GBEM RS10455
gene id: 404380:GBEM_RS10455
uniprot id: B5ECR4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

404380:GBEM RS18230
gene id: 404380:GBEM_RS18230
uniprot id: B5ED26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Membrane

404380:GBEM RS16575
gene id: 404380:GBEM_RS16575
uniprot id: B5EAH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

404380:GBEM RS11690
gene id: 404380:GBEM_RS11690
uniprot id: B5EF39
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

404380:GBEM RS13945
gene id: 404380:GBEM_RS13945
uniprot id: B5EI95
names: Subcellular Location Annotation
messages: Mitochondrion

404380:GBEM RS00835
gene id: 404380:GBEM_RS00835
uniprot id: B5E960
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS02260
gene id: 404380:GBEM_RS02260
uniprot id: B5EBL9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

404380:GBEM RS07540
gene id: 404380:GBEM_RS07540
uniprot id: B5E7Y2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

404380:GBEM RS14330
gene id: 404380:GBEM_RS14330
uniprot id: B5EIH3
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS03355
gene id: 404380:GBEM_RS03355
uniprot id: B5EDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

404380:GBEM RS15085
gene id: 404380:GBEM_RS15085
uniprot id: B5E855
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS01910
gene id: 404380:GBEM_RS01910
uniprot id: B5EAV8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

404380:GBEM RS13045
gene id: 404380:GBEM_RS13045
uniprot id: B5EH85
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

404380:GBEM RS11445
gene id: 404380:GBEM_RS11445
uniprot id: B5EEF4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

404380:GBEM RS02415
gene id: 404380:GBEM_RS02415
uniprot id: B5EBP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

404380:GBEM RS08420
gene id: 404380:GBEM_RS08420
uniprot id: B5E9F1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

404380:GBEM RS04055
gene id: 404380:GBEM_RS04055
uniprot id: B5EEU2
names: Similarity
messages: Belongs to the FPG family.

404380:GBEM RS15995
gene id: 404380:GBEM_RS15995
uniprot id: B5E9M9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

404380:GBEM RS06150
gene id: 404380:GBEM_RS06150
uniprot id: B5EHN3
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS09425
gene id: 404380:GBEM_RS09425
uniprot id: B5EB32
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

404380:GBEM RS04995
gene id: 404380:GBEM_RS04995
uniprot id: B5EGF1
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

404380:GBEM RS01755
gene id: 404380:GBEM_RS01755
uniprot id: B5EAS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS08850
gene id: 404380:GBEM_RS08850
uniprot id: B5EA72
names: Subcellular Location Annotation
messages: Secreted

404380:GBEM RS10420
gene id: 404380:GBEM_RS10420
uniprot id: B5ECQ7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

404380:GBEM RS18205
gene id: 404380:GBEM_RS18205
uniprot id: B5ED21
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

404380:GBEM RS04205
gene id: 404380:GBEM_RS04205
uniprot id: B5EEX2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS20260
gene id: 404380:GBEM_RS20260
uniprot id: B5EGX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

404380:GBEM RS11285
gene id: 404380:GBEM_RS11285
uniprot id: B5EEC2
names: Similarity
messages: Belongs to the hemerythrin family.

404380:GBEM RS17770
gene id: 404380:GBEM_RS17770
uniprot id: B5EC95
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

404380:GBEM RS19840
gene id: 404380:GBEM_RS19840
uniprot id: B5EG54
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

404380:GBEM RS00020
gene id: 404380:GBEM_RS00020
uniprot id: B5E7Q1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

404380:GBEM RS13155
gene id: 404380:GBEM_RS13155
uniprot id: B5EHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

404380:GBEM RS06300
gene id: 404380:GBEM_RS06300
uniprot id: B5EI10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

404380:GBEM RS16260
gene id: 404380:GBEM_RS16260
uniprot id: B5E9T3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

404380:GBEM RS14070
gene id: 404380:GBEM_RS14070
uniprot id: B5EIC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

404380:GBEM RS12305
gene id: 404380:GBEM_RS12305
uniprot id: B5EG06
names: Function
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.

404380:GBEM RS15500
gene id: 404380:GBEM_RS15500
uniprot id: B5E8U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS17080
gene id: 404380:GBEM_RS17080
uniprot id: B5EBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

404380:GBEM RS09880
gene id: 404380:GBEM_RS09880
uniprot id: B5EBW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS07135
gene id: 404380:GBEM_RS07135
uniprot id: B5EIS3
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

404380:GBEM RS11115
gene id: 404380:GBEM_RS11115
uniprot id: B5EE86
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

404380:GBEM RS12885
gene id: 404380:GBEM_RS12885
uniprot id: B5EGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS04715
gene id: 404380:GBEM_RS04715
uniprot id: B5EFR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

404380:GBEM RS16420
gene id: 404380:GBEM_RS16420
uniprot id: B5EAF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

404380:GBEM RS04305
gene id: 404380:GBEM_RS04305
uniprot id: B5EEZ2
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

404380:GBEM RS07590
gene id: 404380:GBEM_RS07590
uniprot id: B5E7Z2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

404380:GBEM RS13420
gene id: 404380:GBEM_RS13420
uniprot id: B5EHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS16840
gene id: 404380:GBEM_RS16840
uniprot id: B5EB78
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

404380:GBEM RS16360
gene id: 404380:GBEM_RS16360
uniprot id: B5EAD8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS03295
gene id: 404380:GBEM_RS03295
uniprot id: B5EDA6
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

404380:GBEM RS09165
gene id: 404380:GBEM_RS09165
uniprot id: B5EAY0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS10655
gene id: 404380:GBEM_RS10655
uniprot id: B5EDE4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

404380:GBEM RS16445
gene id: 404380:GBEM_RS16445
uniprot id: B5EAF4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS15355
gene id: 404380:GBEM_RS15355
uniprot id: B5E8R2
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

404380:GBEM RS13515
gene id: 404380:GBEM_RS13515
uniprot id: B5EHR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

404380:GBEM RS08065
gene id: 404380:GBEM_RS08065
uniprot id: B5E8N8
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS16250
gene id: 404380:GBEM_RS16250
uniprot id: B5E9T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS02305
gene id: 404380:GBEM_RS02305
uniprot id: B5EBM8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

404380:GBEM RS19585
gene id: 404380:GBEM_RS19585
uniprot id: B5EFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

404380:GBEM RS15550
gene id: 404380:GBEM_RS15550
uniprot id: B5E8V0
names: Similarity
messages: Belongs to the peptidase S49 family.

404380:GBEM RS04940
gene id: 404380:GBEM_RS04940
uniprot id: B5EGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

404380:GBEM RS13160
gene id: 404380:GBEM_RS13160
uniprot id: B5EHA7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

404380:GBEM RS06475
gene id: 404380:GBEM_RS06475
uniprot id: B5EI43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

404380:GBEM RS13625
gene id: 404380:GBEM_RS13625
uniprot id: B5EHT5
names: Similarity
messages: Belongs to the peptidase M16 family.

404380:GBEM RS04525
gene id: 404380:GBEM_RS04525
uniprot id: B5EFM7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS07105
gene id: 404380:GBEM_RS07105
uniprot id: B5EIR7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

404380:GBEM RS04920
gene id: 404380:GBEM_RS04920
uniprot id: B5EGD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

404380:GBEM RS04690
gene id: 404380:GBEM_RS04690
uniprot id: B5EFQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

404380:GBEM RS06330
gene id: 404380:GBEM_RS06330
uniprot id: B5EI16
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

404380:GBEM RS20035
gene id: 404380:GBEM_RS20035
uniprot id: B5EG91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

404380:GBEM RS16020
gene id: 404380:GBEM_RS16020
uniprot id: B5E9N4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

404380:GBEM RS04590
gene id: 404380:GBEM_RS04590
uniprot id: B5EFN6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

404380:GBEM RS18415
gene id: 404380:GBEM_RS18415
uniprot id: B5EDQ4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

404380:GBEM RS06470
gene id: 404380:GBEM_RS06470
uniprot id: B5EI42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

404380:GBEM RS17745
gene id: 404380:GBEM_RS17745
uniprot id: B5EC90
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

404380:GBEM RS14575
gene id: 404380:GBEM_RS14575
uniprot id: B5EIW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS06235
gene id: 404380:GBEM_RS06235
uniprot id: B5EHZ6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

404380:GBEM RS04550
gene id: 404380:GBEM_RS04550
uniprot id: B5EFN2
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

404380:GBEM RS04605
gene id: 404380:GBEM_RS04605
uniprot id: B5EFN8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

404380:GBEM RS01140
gene id: 404380:GBEM_RS01140
uniprot id: B5E9W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

404380:GBEM RS14475
gene id: 404380:GBEM_RS14475
uniprot id: B5EIU8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

404380:GBEM RS07150
gene id: 404380:GBEM_RS07150
uniprot id: B5EIS6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

404380:GBEM RS04790
gene id: 404380:GBEM_RS04790
uniprot id: B5EFS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

404380:GBEM RS07355
gene id: 404380:GBEM_RS07355
uniprot id: B5E7U6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

404380:GBEM RS00760
gene id: 404380:GBEM_RS00760
uniprot id: B5E945
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

404380:GBEM RS15640
gene id: 404380:GBEM_RS15640
uniprot id: B5E8W9
names: Similarity
messages: Belongs to the HupF/HypC family.

404380:GBEM RS19565
gene id: 404380:GBEM_RS19565
uniprot id: B5EFF7
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

404380:GBEM RS10845
gene id: 404380:GBEM_RS10845
uniprot id: B5EDI1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS00220
gene id: 404380:GBEM_RS00220
uniprot id: B5EJ48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

404380:GBEM RS19730
gene id: 404380:GBEM_RS19730
uniprot id: B5EFJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

404380:GBEM RS18915
gene id: 404380:GBEM_RS18915
uniprot id: B5EEJ5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

404380:GBEM RS18805
gene id: 404380:GBEM_RS18805
uniprot id: B5EEH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

404380:GBEM RS16960
gene id: 404380:GBEM_RS16960
uniprot id: B5EB97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

404380:GBEM RS09265
gene id: 404380:GBEM_RS09265
uniprot id: B5EB00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

404380:GBEM RS03780
gene id: 404380:GBEM_RS03780
uniprot id: B5EE52
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

404380:GBEM RS09655
gene id: 404380:GBEM_RS09655
uniprot id: B5EBR7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

404380:GBEM RS10040
gene id: 404380:GBEM_RS10040
uniprot id: B5EBZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

404380:GBEM RS06225
gene id: 404380:GBEM_RS06225
uniprot id: B5EHZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

404380:GBEM RS16495
gene id: 404380:GBEM_RS16495
uniprot id: B5EAG4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

404380:GBEM RS10915
gene id: 404380:GBEM_RS10915
uniprot id: B5EDJ6
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

404380:GBEM RS11960
gene id: 404380:GBEM_RS11960
uniprot id: B5EF92
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

404380:GBEM RS11670
gene id: 404380:GBEM_RS11670
uniprot id: B5EF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

404380:GBEM RS18320
gene id: 404380:GBEM_RS18320
uniprot id: B5EDN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

404380:GBEM RS17110
gene id: 404380:GBEM_RS17110
uniprot id: B5EBC7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

404380:GBEM RS01835
gene id: 404380:GBEM_RS01835
uniprot id: B5EAU3
names: Similarity
messages: Belongs to the UPF0045 family.

404380:GBEM RS04825
gene id: 404380:GBEM_RS04825
uniprot id: B5EFT4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

404380:GBEM RS08170
gene id: 404380:GBEM_RS08170
uniprot id: B5E8Q9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

404380:GBEM RS16285
gene id: 404380:GBEM_RS16285
uniprot id: B5E9T8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

404380:GBEM RS00815
gene id: 404380:GBEM_RS00815
uniprot id: B5E956
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

404380:GBEM RS10155
gene id: 404380:GBEM_RS10155
uniprot id: B5ECK4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

404380:GBEM RS16805
gene id: 404380:GBEM_RS16805
uniprot id: B5EB71
names: Similarity
messages: Belongs to the peptidase C40 family.

404380:GBEM RS00975
gene id: 404380:GBEM_RS00975
uniprot id: B5E988
names: Similarity
messages: Belongs to the UPF0502 family.

404380:GBEM RS01175
gene id: 404380:GBEM_RS01175
uniprot id: B5E9W7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

404380:GBEM RS20270
gene id: 404380:GBEM_RS20270
uniprot id: B5EGY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

404380:GBEM RS07365
gene id: 404380:GBEM_RS07365
uniprot id: B5E7U8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

404380:GBEM RS09270
gene id: 404380:GBEM_RS09270
uniprot id: B5EB01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

404380:GBEM RS07505
gene id: 404380:GBEM_RS07505
uniprot id: B5E7X5
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS04020
gene id: 404380:GBEM_RS04020
uniprot id: B5EET5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

404380:GBEM RS21030
gene id: 404380:GBEM_RS21030
uniprot id: B5E9J3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

404380:GBEM RS09465
gene id: 404380:GBEM_RS09465
uniprot id: B5EB40
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

404380:GBEM RS11065
gene id: 404380:GBEM_RS11065
uniprot id: B5EE76
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS18350
gene id: 404380:GBEM_RS18350
uniprot id: B5EDP2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

404380:GBEM RS17875
gene id: 404380:GBEM_RS17875
uniprot id: B5ECV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

404380:GBEM RS09285
gene id: 404380:GBEM_RS09285
uniprot id: B5EB04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

404380:GBEM RS09190
gene id: 404380:GBEM_RS09190
uniprot id: B5EAY5
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS06230
gene id: 404380:GBEM_RS06230
uniprot id: B5EHZ5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

404380:GBEM RS19950
gene id: 404380:GBEM_RS19950
uniprot id: B5EG74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

404380:GBEM RS01005
gene id: 404380:GBEM_RS01005
uniprot id: B5E994
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

404380:GBEM RS05295
gene id: 404380:GBEM_RS05295
uniprot id: B5EGK9
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS07300
gene id: 404380:GBEM_RS07300
uniprot id: B5E7T4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

404380:GBEM RS06325
gene id: 404380:GBEM_RS06325
uniprot id: B5EI15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

404380:GBEM RS20150
gene id: 404380:GBEM_RS20150
uniprot id: B5EGB3
names: Cofactor
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per subunit.

404380:GBEM RS06580
gene id: 404380:GBEM_RS06580
uniprot id: B5EI64
names: Similarity
messages: Belongs to the peptidase M16 family.

404380:GBEM RS08930
gene id: 404380:GBEM_RS08930
uniprot id: B5EA89
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

404380:GBEM RS19740
gene id: 404380:GBEM_RS19740
uniprot id: B5EFJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

404380:GBEM RS04620
gene id: 404380:GBEM_RS04620
uniprot id: B5EFP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

404380:GBEM RS03230
gene id: 404380:GBEM_RS03230
uniprot id: B5ED94
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS08315
gene id: 404380:GBEM_RS08315
uniprot id: B5E9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

404380:GBEM RS16365
gene id: 404380:GBEM_RS16365
uniprot id: B5EAD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

404380:GBEM RS12065
gene id: 404380:GBEM_RS12065
uniprot id: B5EFV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

404380:GBEM RS11335
gene id: 404380:GBEM_RS11335
uniprot id: B5EED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

404380:GBEM RS11090
gene id: 404380:GBEM_RS11090
uniprot id: B5EE81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

404380:GBEM RS18135
gene id: 404380:GBEM_RS18135
uniprot id: B5ED07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

404380:GBEM RS06730
gene id: 404380:GBEM_RS06730
uniprot id: B5EIJ3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

404380:GBEM RS13140
gene id: 404380:GBEM_RS13140
uniprot id: B5EHA3
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS00475
gene id: 404380:GBEM_RS00475
uniprot id: B5E8E5
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS04900
gene id: 404380:GBEM_RS04900
uniprot id: B5EGD2
names: Similarity
messages: Belongs to the UPF0047 family.

404380:GBEM RS09795
gene id: 404380:GBEM_RS09795
uniprot id: B5EBU7
names: Similarity
messages: Belongs to the TrpC family.

404380:GBEM RS03145
gene id: 404380:GBEM_RS03145
uniprot id: B5ED77
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

404380:GBEM RS06135
gene id: 404380:GBEM_RS06135
uniprot id: B5EHN0
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

404380:GBEM RS19150
gene id: 404380:GBEM_RS19150
uniprot id: B5EEP3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

404380:GBEM RS14490
gene id: 404380:GBEM_RS14490
uniprot id: B5EIV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS02995
gene id: 404380:GBEM_RS02995
uniprot id: B5ED46
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

404380:GBEM RS17515
gene id: 404380:GBEM_RS17515
uniprot id: B5EC45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

404380:GBEM RS20145
gene id: 404380:GBEM_RS20145
uniprot id: B5EGB2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS10950
gene id: 404380:GBEM_RS10950
uniprot id: B5EDK3
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS00755
gene id: 404380:GBEM_RS00755
uniprot id: B5E944
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

404380:GBEM RS16320
gene id: 404380:GBEM_RS16320
uniprot id: B5EAD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS00930
gene id: 404380:GBEM_RS00930
uniprot id: B5E979
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

404380:GBEM RS00480
gene id: 404380:GBEM_RS00480
uniprot id: B5E8E6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

404380:GBEM RS17965
gene id: 404380:GBEM_RS17965
uniprot id: B5ECX3
names: Similarity
messages: Belongs to the DEAD box helicase family.

404380:GBEM RS17085
gene id: 404380:GBEM_RS17085
uniprot id: B5EBC2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS16915
gene id: 404380:GBEM_RS16915
uniprot id: B5EB93
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

404380:GBEM RS00885
gene id: 404380:GBEM_RS00885
uniprot id: B5E970
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

404380:GBEM RS07510
gene id: 404380:GBEM_RS07510
uniprot id: B5E7X6
names: Similarity
messages: Belongs to the UPF0235 family.

404380:GBEM RS05250
gene id: 404380:GBEM_RS05250
uniprot id: B5EGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

404380:GBEM RS06375
gene id: 404380:GBEM_RS06375
uniprot id: B5EI26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

404380:GBEM RS15645
gene id: 404380:GBEM_RS15645
uniprot id: B5E8X0
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

404380:GBEM RS18180
gene id: 404380:GBEM_RS18180
uniprot id: B5ED16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

404380:GBEM RS01075
gene id: 404380:GBEM_RS01075
uniprot id: B5E9U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

404380:GBEM RS14120
gene id: 404380:GBEM_RS14120
uniprot id: B5EID1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

404380:GBEM RS09545
gene id: 404380:GBEM_RS09545
uniprot id: B5EB56
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

404380:GBEM RS07530
gene id: 404380:GBEM_RS07530
uniprot id: B5E7Y0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

404380:GBEM RS20135
gene id: 404380:GBEM_RS20135
uniprot id: B5EGB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

404380:GBEM RS20045
gene id: 404380:GBEM_RS20045
uniprot id: B5EG93
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

404380:GBEM RS18745
gene id: 404380:GBEM_RS18745
uniprot id: B5EDW9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

404380:GBEM RS16050
gene id: 404380:GBEM_RS16050
uniprot id: B5E9P0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

404380:GBEM RS09865
gene id: 404380:GBEM_RS09865
uniprot id: B5EBW2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

404380:GBEM RS18875
gene id: 404380:GBEM_RS18875
uniprot id: B5EEI7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS02115
gene id: 404380:GBEM_RS02115
uniprot id: B5EBI9
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS13130
gene id: 404380:GBEM_RS13130
uniprot id: B5EHA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

404380:GBEM RS08685
gene id: 404380:GBEM_RS08685
uniprot id: B5EA40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

404380:GBEM RS16985
gene id: 404380:GBEM_RS16985
uniprot id: B5EBA3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

404380:GBEM RS15125
gene id: 404380:GBEM_RS15125
uniprot id: B5E864
names: Similarity
messages: Belongs to the UPF0751 family.

404380:GBEM RS11905
gene id: 404380:GBEM_RS11905
uniprot id: B5EF81
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

404380:GBEM RS05460
gene id: 404380:GBEM_RS05460
uniprot id: B5EH05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

404380:GBEM RS19820
gene id: 404380:GBEM_RS19820
uniprot id: B5EG50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

404380:GBEM RS03580
gene id: 404380:GBEM_RS03580
uniprot id: B5EE12
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS18030
gene id: 404380:GBEM_RS18030
uniprot id: B5ECY6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS18215
gene id: 404380:GBEM_RS18215
uniprot id: B5ED23
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

404380:GBEM RS06650
gene id: 404380:GBEM_RS06650
uniprot id: B5EI79
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

404380:GBEM RS08630
gene id: 404380:GBEM_RS08630
uniprot id: B5E9J1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

404380:GBEM RS14075
gene id: 404380:GBEM_RS14075
uniprot id: B5EIC2
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS04680
gene id: 404380:GBEM_RS04680
uniprot id: B5EFQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

404380:GBEM RS02020
gene id: 404380:GBEM_RS02020
uniprot id: B5EBH0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

404380:GBEM RS02280
gene id: 404380:GBEM_RS02280
uniprot id: B5EBM3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

404380:GBEM RS14175
gene id: 404380:GBEM_RS14175
uniprot id: B5EIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

404380:GBEM RS04815
gene id: 404380:GBEM_RS04815
uniprot id: B5EFT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

404380:GBEM RS19095
gene id: 404380:GBEM_RS19095
uniprot id: B5EEN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

404380:GBEM RS13180
gene id: 404380:GBEM_RS13180
uniprot id: B5EHB1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

404380:GBEM RS10695
gene id: 404380:GBEM_RS10695
uniprot id: B5EDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

404380:GBEM RS14885
gene id: 404380:GBEM_RS14885
uniprot id: B5E818
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS17285
gene id: 404380:GBEM_RS17285
uniprot id: B5EBG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

404380:GBEM RS02805
gene id: 404380:GBEM_RS02805
uniprot id: B5ECG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

404380:GBEM RS14015
gene id: 404380:GBEM_RS14015
uniprot id: B5EIA9
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

404380:GBEM RS19540
gene id: 404380:GBEM_RS19540
uniprot id: B5EFF2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS13005
gene id: 404380:GBEM_RS13005
uniprot id: B5EH77
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS19120
gene id: 404380:GBEM_RS19120
uniprot id: B5EEN7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

404380:GBEM RS05855
gene id: 404380:GBEM_RS05855
uniprot id: B5EHH6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS15945
gene id: 404380:GBEM_RS15945
uniprot id: B5E9M0
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12300
gene id: 404380:GBEM_RS12300
uniprot id: B5EG05
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

404380:GBEM RS09510
gene id: 404380:GBEM_RS09510
uniprot id: B5EB49
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

404380:GBEM RS13670
gene id: 404380:GBEM_RS13670
uniprot id: B5EHU4
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS09790
gene id: 404380:GBEM_RS09790
uniprot id: B5EBU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

404380:GBEM RS14845
gene id: 404380:GBEM_RS14845
uniprot id: B5EJ25
names: Similarity
messages: Belongs to the HepT RNase toxin family.

404380:GBEM RS14400
gene id: 404380:GBEM_RS14400
uniprot id: B5EII7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

404380:GBEM RS20245
gene id: 404380:GBEM_RS20245
uniprot id: B5EGX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

404380:GBEM RS03400
gene id: 404380:GBEM_RS03400
uniprot id: B5EDX6
names: Similarity
messages: Belongs to the peptidase M16 family.

404380:GBEM RS03070
gene id: 404380:GBEM_RS03070
uniprot id: B5ED61
names: Similarity
messages: Belongs to the UPF0234 family.

404380:GBEM RS04025
gene id: 404380:GBEM_RS04025
uniprot id: B5EET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

404380:GBEM RS15350
gene id: 404380:GBEM_RS15350
uniprot id: B5E8A6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

404380:GBEM RS17125
gene id: 404380:GBEM_RS17125
uniprot id: B5EBD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

404380:GBEM RS08875
gene id: 404380:GBEM_RS08875
uniprot id: B5EA78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

404380:GBEM RS06240
gene id: 404380:GBEM_RS06240
uniprot id: B5EHZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

404380:GBEM RS19085
gene id: 404380:GBEM_RS19085
uniprot id: B5EEN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

404380:GBEM RS01595
gene id: 404380:GBEM_RS01595
uniprot id: B5EAP1
names: Function
names: Similarity
messages: Belongs to the MerB family.
messages: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.

404380:GBEM RS10440
gene id: 404380:GBEM_RS10440
uniprot id: B5ECR1
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

404380:GBEM RS15340
gene id: 404380:GBEM_RS15340
uniprot id: B5E8A4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

404380:GBEM RS19800
gene id: 404380:GBEM_RS19800
uniprot id: B5EG46
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS00180
gene id: 404380:GBEM_RS00180
uniprot id: B5EJ40
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

404380:GBEM RS11195
gene id: 404380:GBEM_RS11195
uniprot id: B5EEA2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

404380:GBEM RS13985
gene id: 404380:GBEM_RS13985
uniprot id: B5EIA3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

404380:GBEM RS15675
gene id: 404380:GBEM_RS15675
uniprot id: B5E8X6
names: Cofactor
names: Subunit
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: Heterodimer of a large and a small subunit.

404380:GBEM RS16300
gene id: 404380:GBEM_RS16300
uniprot id: B5E9U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS08190
gene id: 404380:GBEM_RS08190
uniprot id: B5E9A6
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

404380:GBEM RS09195
gene id: 404380:GBEM_RS09195
uniprot id: B5EAY6
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS09800
gene id: 404380:GBEM_RS09800
uniprot id: B5EBU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

404380:GBEM RS12430
gene id: 404380:GBEM_RS12430
uniprot id: B5EG31
names: Similarity
messages: Belongs to the CcdB toxin family.

404380:GBEM RS15990
gene id: 404380:GBEM_RS15990
uniprot id: B5E9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

404380:GBEM RS07160
gene id: 404380:GBEM_RS07160
uniprot id: B5EIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

404380:GBEM RS14945
gene id: 404380:GBEM_RS14945
uniprot id: B5E829
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

404380:GBEM RS14325
gene id: 404380:GBEM_RS14325
uniprot id: B5EIH2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS00690
gene id: 404380:GBEM_RS00690
uniprot id: B5E930
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

404380:GBEM RS00710
gene id: 404380:GBEM_RS00710
uniprot id: B5E934
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

404380:GBEM RS03160
gene id: 404380:GBEM_RS03160
uniprot id: B5ED80
names: Similarity
messages: Belongs to the peptidase C40 family.

404380:GBEM RS17695
gene id: 404380:GBEM_RS17695
uniprot id: B5EC81
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

404380:GBEM RS15025
gene id: 404380:GBEM_RS15025
uniprot id: B5E844
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

404380:GBEM RS06555
gene id: 404380:GBEM_RS06555
uniprot id: B5EI59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

404380:GBEM RS13395
gene id: 404380:GBEM_RS13395
uniprot id: B5EHF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS03500
gene id: 404380:GBEM_RS03500
uniprot id: B5EDZ6
names: Similarity
messages: Belongs to the peptidase S16 family.

404380:GBEM RS04760
gene id: 404380:GBEM_RS04760
uniprot id: B5EFR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

404380:GBEM RS13685
gene id: 404380:GBEM_RS13685
uniprot id: B5EHU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

404380:GBEM RS16240
gene id: 404380:GBEM_RS16240
uniprot id: B5E9S9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

404380:GBEM RS18995
gene id: 404380:GBEM_RS18995
uniprot id: B5EEL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

404380:GBEM RS07335
gene id: 404380:GBEM_RS07335
uniprot id: B5E7U2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

404380:GBEM RS18170
gene id: 404380:GBEM_RS18170
uniprot id: B5ED14
names: Similarity
messages: Belongs to the Nudix hydrolase family.

404380:GBEM RS00615
gene id: 404380:GBEM_RS00615
uniprot id: B5E915
names: Cofactor
names: Similarity
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.

404380:GBEM RS10215
gene id: 404380:GBEM_RS10215
uniprot id: B5ECL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

404380:GBEM RS19915
gene id: 404380:GBEM_RS19915
uniprot id: B5EG67
names: Similarity
messages: Belongs to the YkuD family.

404380:GBEM RS07895
gene id: 404380:GBEM_RS07895
uniprot id: B5E8K4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

404380:GBEM RS08435
gene id: 404380:GBEM_RS08435
uniprot id: B5E9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

404380:GBEM RS16885
gene id: 404380:GBEM_RS16885
uniprot id: B5EB87
names: Similarity
messages: Belongs to the acylphosphatase family.

404380:GBEM RS13175
gene id: 404380:GBEM_RS13175
uniprot id: B5EHB0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

404380:GBEM RS13790
gene id: 404380:GBEM_RS13790
uniprot id: B5EHW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

404380:GBEM RS09810
gene id: 404380:GBEM_RS09810
uniprot id: B5EBV1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

404380:GBEM RS16090
gene id: 404380:GBEM_RS16090
uniprot id: B5E9Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

404380:GBEM RS03550
gene id: 404380:GBEM_RS03550
uniprot id: B5EE06
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

404380:GBEM RS14055
gene id: 404380:GBEM_RS14055
uniprot id: B5EIB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

404380:GBEM RS10540
gene id: 404380:GBEM_RS10540
uniprot id: B5ECT2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS08145
gene id: 404380:GBEM_RS08145
uniprot id: B5E8Q4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

404380:GBEM RS04385
gene id: 404380:GBEM_RS04385
uniprot id: B5EFJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS00400
gene id: 404380:GBEM_RS00400
uniprot id: B5E8C9
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS14705
gene id: 404380:GBEM_RS14705
uniprot id: B5EIZ3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS04190
gene id: 404380:GBEM_RS04190
uniprot id: B5EEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

404380:GBEM RS02475
gene id: 404380:GBEM_RS02475
uniprot id: B5ECA2
names: Similarity
messages: Belongs to the peptidase S24 family.

404380:GBEM RS20240
gene id: 404380:GBEM_RS20240
uniprot id: B5EGX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

404380:GBEM RS04685
gene id: 404380:GBEM_RS04685
uniprot id: B5EFQ4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

404380:GBEM RS14620
gene id: 404380:GBEM_RS14620
uniprot id: B5EIX7
names: Similarity
messages: Belongs to the cytochrome c-552 family.

404380:GBEM RS02635
gene id: 404380:GBEM_RS02635
uniprot id: B5ECD6
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS12170
gene id: 404380:GBEM_RS12170
uniprot id: B5EFX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

404380:GBEM RS03385
gene id: 404380:GBEM_RS03385
uniprot id: B5EDC5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

404380:GBEM RS10580
gene id: 404380:GBEM_RS10580
uniprot id: B5EDC9
names: Similarity
messages: Belongs to the universal stress protein A family.

404380:GBEM RS01170
gene id: 404380:GBEM_RS01170
uniprot id: B5E9W6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS15245
gene id: 404380:GBEM_RS15245
uniprot id: B5E888
names: Similarity
messages: Belongs to the peptidase S8 family.

404380:GBEM RS11675
gene id: 404380:GBEM_RS11675
uniprot id: B5EF36
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

404380:GBEM RS17845
gene id: 404380:GBEM_RS17845
uniprot id: B5ECU9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

404380:GBEM RS08040
gene id: 404380:GBEM_RS08040
uniprot id: B5E8N3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS06425
gene id: 404380:GBEM_RS06425
uniprot id: B5EI33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS05175
gene id: 404380:GBEM_RS05175
uniprot id: B5EGI4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

404380:GBEM RS11320
gene id: 404380:GBEM_RS11320
uniprot id: B5EEC9
names: Similarity
messages: Belongs to the hemerythrin family.

404380:GBEM RS03025
gene id: 404380:GBEM_RS03025
uniprot id: B5ED52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

404380:GBEM RS06305
gene id: 404380:GBEM_RS06305
uniprot id: B5EI11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

404380:GBEM RS05895
gene id: 404380:GBEM_RS05895
uniprot id: B5EHI5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

404380:GBEM RS08300
gene id: 404380:GBEM_RS08300
uniprot id: B5E9C8
names: Similarity
messages: Belongs to the citrate synthase family.

404380:GBEM RS05885
gene id: 404380:GBEM_RS05885
uniprot id: B5EHI3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

404380:GBEM RS02915
gene id: 404380:GBEM_RS02915
uniprot id: B5ECI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

404380:GBEM RS04725
gene id: 404380:GBEM_RS04725
uniprot id: B5EFR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

404380:GBEM RS02880
gene id: 404380:GBEM_RS02880
uniprot id: B5ECI1
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS16275
gene id: 404380:GBEM_RS16275
uniprot id: B5E9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

404380:GBEM RS19490
gene id: 404380:GBEM_RS19490
uniprot id: B5EFE2
names: Similarity
messages: Belongs to the citrate synthase family.

404380:GBEM RS15370
gene id: 404380:GBEM_RS15370
uniprot id: B5E8R5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

404380:GBEM RS13780
gene id: 404380:GBEM_RS13780
uniprot id: B5EHW6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

404380:GBEM RS10345
gene id: 404380:GBEM_RS10345
uniprot id: B5ECP2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

404380:GBEM RS03765
gene id: 404380:GBEM_RS03765
uniprot id: B5EE49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS18425
gene id: 404380:GBEM_RS18425
uniprot id: B5EDQ6
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

404380:GBEM RS04375
gene id: 404380:GBEM_RS04375
uniprot id: B5EFJ7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS10020
gene id: 404380:GBEM_RS10020
uniprot id: B5EBZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

404380:GBEM RS09330
gene id: 404380:GBEM_RS09330
uniprot id: B5EB14
names: Similarity
messages: Belongs to the Lgt family.

404380:GBEM RS04135
gene id: 404380:GBEM_RS04135
uniprot id: B5EEV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

404380:GBEM RS06345
gene id: 404380:GBEM_RS06345
uniprot id: B5EI19
names: Similarity
messages: Belongs to the aspartokinase family.

404380:GBEM RS06390
gene id: 404380:GBEM_RS06390
uniprot id: B5EI29
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

404380:GBEM RS10225
gene id: 404380:GBEM_RS10225
uniprot id: B5ECL8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

404380:GBEM RS19770
gene id: 404380:GBEM_RS19770
uniprot id: B5EG40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

404380:GBEM RS12535
gene id: 404380:GBEM_RS12535
uniprot id: B5EGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

404380:GBEM RS12175
gene id: 404380:GBEM_RS12175
uniprot id: B5EFX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

404380:GBEM RS01020
gene id: 404380:GBEM_RS01020
uniprot id: B5E997
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

404380:GBEM RS20255
gene id: 404380:GBEM_RS20255
uniprot id: B5EGX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

404380:GBEM RS06280
gene id: 404380:GBEM_RS06280
uniprot id: B5EI06
names: Subcellular Location Annotation
messages: Cytoplasm

404380:GBEM RS13710
gene id: 404380:GBEM_RS13710
uniprot id: B5EHV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

404380:GBEM RS06880
gene id: 404380:GBEM_RS06880
uniprot id: B5EIM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

404380:GBEM RS13815
gene id: 404380:GBEM_RS13815
uniprot id: B5EHX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

404380:GBEM RS05485
gene id: 404380:GBEM_RS05485
uniprot id: B5EH11
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

404380:GBEM RS06870
gene id: 404380:GBEM_RS06870
uniprot id: B5EIM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

404380:GBEM RS05000
gene id: 404380:GBEM_RS05000
uniprot id: B5EGF2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

404380:GBEM RS01145
gene id: 404380:GBEM_RS01145
uniprot id: B5E9W2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

404380:GBEM RS14135
gene id: 404380:GBEM_RS14135
uniprot id: B5EID4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

404380:GBEM RS07360
gene id: 404380:GBEM_RS07360
uniprot id: B5E7U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

404380:GBEM RS12830
gene id: 404380:GBEM_RS12830
uniprot id: B5EGU5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

404380:GBEM RS06140
gene id: 404380:GBEM_RS06140
uniprot id: B5EHN1
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

404380:GBEM RS15655
gene id: 404380:GBEM_RS15655
uniprot id: B5E8X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

404380:GBEM RS09960
gene id: 404380:GBEM_RS09960
uniprot id: B5EBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

404380:GBEM RS06510
gene id: 404380:GBEM_RS06510
uniprot id: B5EI50
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

404380:GBEM RS05300
gene id: 404380:GBEM_RS05300
uniprot id: B5EGL0
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS17295
gene id: 404380:GBEM_RS17295
uniprot id: B5EC01
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

404380:GBEM RS00685
gene id: 404380:GBEM_RS00685
uniprot id: B5E929
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

404380:GBEM RS15555
gene id: 404380:GBEM_RS15555
uniprot id: B5E8V1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

404380:GBEM RS17020
gene id: 404380:GBEM_RS17020
uniprot id: B5EBA9
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS10110
gene id: 404380:GBEM_RS10110
uniprot id: B5ECJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

404380:GBEM RS03525
gene id: 404380:GBEM_RS03525
uniprot id: B5EE01
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

404380:GBEM RS13725
gene id: 404380:GBEM_RS13725
uniprot id: B5EHV5
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

404380:GBEM RS06430
gene id: 404380:GBEM_RS06430
uniprot id: B5EI34
names: Similarity
messages: Belongs to the GSP E family.

404380:GBEM RS06700
gene id: 404380:GBEM_RS06700
uniprot id: B5EI88
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

404380:GBEM RS04805
gene id: 404380:GBEM_RS04805
uniprot id: B5EFS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

404380:GBEM RS08645
gene id: 404380:GBEM_RS08645
uniprot id: B5E9J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

404380:GBEM RS05310
gene id: 404380:GBEM_RS05310
uniprot id: B5EGL2
names: Similarity
messages: Belongs to the bacterial secretin family.

404380:GBEM RS19600
gene id: 404380:GBEM_RS19600
uniprot id: B5EFG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

404380:GBEM RS04695
gene id: 404380:GBEM_RS04695
uniprot id: B5EFQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

404380:GBEM RS01600
gene id: 404380:GBEM_RS01600
uniprot id: B5EAP2
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS04540
gene id: 404380:GBEM_RS04540
uniprot id: B5EFN0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

404380:GBEM RS08205
gene id: 404380:GBEM_RS08205
uniprot id: B5E9A9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

404380:GBEM RS14435
gene id: 404380:GBEM_RS14435
uniprot id: B5EIU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

404380:GBEM RS07960
gene id: 404380:GBEM_RS07960
uniprot id: B5E8L7
names: Subcellular Location Annotation
messages: Membrane

404380:GBEM RS18290
gene id: 404380:GBEM_RS18290
uniprot id: B5EDM9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

404380:GBEM RS12260
gene id: 404380:GBEM_RS12260
uniprot id: B5EFZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.