398580:DSHI RS10240
gene id: 398580:DSHI_RS10240
uniprot id: A8LP66
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

398580:DSHI RS14870
gene id: 398580:DSHI_RS14870
uniprot id: A8LJR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

398580:DSHI RS02235
gene id: 398580:DSHI_RS02235
uniprot id: A8LN40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

398580:DSHI RS03380
gene id: 398580:DSHI_RS03380
uniprot id: A8LQC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

398580:DSHI RS14630
gene id: 398580:DSHI_RS14630
uniprot id: A8LJL4
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

398580:DSHI RS18765
gene id: 398580:DSHI_RS18765
uniprot id: A8LT78
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS19695
gene id: 398580:DSHI_RS19695
uniprot id: A8LTR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

398580:DSHI RS11015
gene id: 398580:DSHI_RS11015
uniprot id: A8LQN3
names: Similarity
messages: Belongs to the peptidase C40 family.

398580:DSHI RS12655
gene id: 398580:DSHI_RS12655
uniprot id: A8LSM3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

398580:DSHI RS14355
gene id: 398580:DSHI_RS14355
uniprot id: A8LJ66
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

398580:DSHI RS15965
gene id: 398580:DSHI_RS15965
uniprot id: A8LLX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

398580:DSHI RS16455
gene id: 398580:DSHI_RS16455
uniprot id: A8LMQ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

398580:DSHI RS08710
gene id: 398580:DSHI_RS08710
uniprot id: A8LLS6
names: Similarity
messages: Belongs to the BolA/IbaG family.

398580:DSHI RS10420
gene id: 398580:DSHI_RS10420
uniprot id: C5ZZE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

398580:DSHI RS01485
gene id: 398580:DSHI_RS01485
uniprot id: A8LM70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

398580:DSHI RS10905
gene id: 398580:DSHI_RS10905
uniprot id: A8LQL2
names: Similarity
messages: Belongs to the pirin family.

398580:DSHI RS13850
gene id: 398580:DSHI_RS13850
uniprot id: A8LIM0
names: Similarity
messages: Belongs to the GARS family.

398580:DSHI RS14065
gene id: 398580:DSHI_RS14065
uniprot id: A8LJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

398580:DSHI RS07590
gene id: 398580:DSHI_RS07590
uniprot id: A8LK33
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

398580:DSHI RS14505
gene id: 398580:DSHI_RS14505
uniprot id: A8LJI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

398580:DSHI RS07645
gene id: 398580:DSHI_RS07645
uniprot id: A8LK44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

398580:DSHI RS17420
gene id: 398580:DSHI_RS17420
uniprot id: A8LPA8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

398580:DSHI RS16640
gene id: 398580:DSHI_RS16640
uniprot id: A8LMU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

398580:DSHI RS21035
gene id: 398580:DSHI_RS21035
uniprot id: A8LUI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS03080
gene id: 398580:DSHI_RS03080
uniprot id: A8LPM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS01205
gene id: 398580:DSHI_RS01205
uniprot id: A8LLI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

398580:DSHI RS20660
gene id: 398580:DSHI_RS20660
uniprot id: A8LUB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

398580:DSHI RS09350
gene id: 398580:DSHI_RS09350
uniprot id: A8LN61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS07785
gene id: 398580:DSHI_RS07785
uniprot id: A8LK72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

398580:DSHI RS02770
gene id: 398580:DSHI_RS02770
uniprot id: A8LPH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS19020
gene id: 398580:DSHI_RS19020
uniprot id: A8LTD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS02785
gene id: 398580:DSHI_RS02785
uniprot id: A8LPH3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

398580:DSHI RS08860
gene id: 398580:DSHI_RS08860
uniprot id: A8LMD7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

398580:DSHI RS00405
gene id: 398580:DSHI_RS00405
uniprot id: A8LKI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

398580:DSHI RS06320
gene id: 398580:DSHI_RS06320
uniprot id: A8LIC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

398580:DSHI RS03745
gene id: 398580:DSHI_RS03745
uniprot id: A8LQT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS17455
gene id: 398580:DSHI_RS17455
uniprot id: A8LPB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

398580:DSHI RS05175
gene id: 398580:DSHI_RS05175
uniprot id: A8LSD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS10255
gene id: 398580:DSHI_RS10255
uniprot id: A8LP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS09175
gene id: 398580:DSHI_RS09175
uniprot id: A8LMJ7
names: Similarity
messages: Belongs to the TrpC family.

398580:DSHI RS06440
gene id: 398580:DSHI_RS06440
uniprot id: A8LIF1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

398580:DSHI RS06330
gene id: 398580:DSHI_RS06330
uniprot id: A8LIC9
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

398580:DSHI RS17995
gene id: 398580:DSHI_RS17995
uniprot id: A8LQ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

398580:DSHI RS13920
gene id: 398580:DSHI_RS13920
uniprot id: A8LIN4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

398580:DSHI RS03365
gene id: 398580:DSHI_RS03365
uniprot id: A8LQB8
names: Subcellular Location Annotation
messages: Cell inner membrane

398580:DSHI RS07695
gene id: 398580:DSHI_RS07695
uniprot id: A8LK54
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

398580:DSHI RS05540
gene id: 398580:DSHI_RS05540
uniprot id: A8LSL1
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS12230
gene id: 398580:DSHI_RS12230
uniprot id: A8LS45
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

398580:DSHI RS11435
gene id: 398580:DSHI_RS11435
uniprot id: A8LR63
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

398580:DSHI RS05855
gene id: 398580:DSHI_RS05855
uniprot id: A8LHU1
names: Similarity
messages: Belongs to the threonine synthase family.

398580:DSHI RS03560
gene id: 398580:DSHI_RS03560
uniprot id: A8LQF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

398580:DSHI RS17765
gene id: 398580:DSHI_RS17765
uniprot id: A8LQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

398580:DSHI RS12810
gene id: 398580:DSHI_RS12810
uniprot id: A8LSQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

398580:DSHI RS07285
gene id: 398580:DSHI_RS07285
uniprot id: A8LJF0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

398580:DSHI RS02510
gene id: 398580:DSHI_RS02510
uniprot id: A8LNT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS04960
gene id: 398580:DSHI_RS04960
uniprot id: A8LS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS16320
gene id: 398580:DSHI_RS16320
uniprot id: A8LMM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

398580:DSHI RS10750
gene id: 398580:DSHI_RS10750
uniprot id: C5ZZE3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

398580:DSHI RS17755
gene id: 398580:DSHI_RS17755
uniprot id: A8LQ01
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

398580:DSHI RS04665
gene id: 398580:DSHI_RS04665
uniprot id: A8LRV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

398580:DSHI RS08405
gene id: 398580:DSHI_RS08405
uniprot id: A8LLL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS08880
gene id: 398580:DSHI_RS08880
uniprot id: A8LME1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

398580:DSHI RS20120
gene id: 398580:DSHI_RS20120
uniprot id: A8LU16
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

398580:DSHI RS01295
gene id: 398580:DSHI_RS01295
uniprot id: A8LLJ9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

398580:DSHI RS03075
gene id: 398580:DSHI_RS03075
uniprot id: A8LPM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS13620
gene id: 398580:DSHI_RS13620
uniprot id: A8LIH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

398580:DSHI RS17530
gene id: 398580:DSHI_RS17530
uniprot id: A8LPD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

398580:DSHI RS14385
gene id: 398580:DSHI_RS14385
uniprot id: A8LJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

398580:DSHI RS20345
gene id: 398580:DSHI_RS20345
uniprot id: A8LTD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS17985
gene id: 398580:DSHI_RS17985
uniprot id: A8LQ47
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

398580:DSHI RS18275
gene id: 398580:DSHI_RS18275
uniprot id: A8LSX7
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

398580:DSHI RS06645
gene id: 398580:DSHI_RS06645
uniprot id: A8LIT2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

398580:DSHI RS14390
gene id: 398580:DSHI_RS14390
uniprot id: A8LJ73
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS08260
gene id: 398580:DSHI_RS08260
uniprot id: A8LL01
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

398580:DSHI RS10680
gene id: 398580:DSHI_RS10680
uniprot id: A8LPY2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

398580:DSHI RS19555
gene id: 398580:DSHI_RS19555
uniprot id: A8LT46
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

398580:DSHI RS01150
gene id: 398580:DSHI_RS01150
uniprot id: A8LLG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

398580:DSHI RS10840
gene id: 398580:DSHI_RS10840
uniprot id: A8LQJ9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS06120
gene id: 398580:DSHI_RS06120
uniprot id: A8LI87
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

398580:DSHI RS09150
gene id: 398580:DSHI_RS09150
uniprot id: A8LMJ2
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

398580:DSHI RS06850
gene id: 398580:DSHI_RS06850
uniprot id: A8LIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

398580:DSHI RS14470
gene id: 398580:DSHI_RS14470
uniprot id: A8LJI1
names: Similarity
messages: Belongs to the autoinducer synthase family.

398580:DSHI RS16170
gene id: 398580:DSHI_RS16170
uniprot id: A8LM14
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

398580:DSHI RS15530
gene id: 398580:DSHI_RS15530
uniprot id: A8LL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

398580:DSHI RS01060
gene id: 398580:DSHI_RS01060
uniprot id: A8LLF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

398580:DSHI RS09270
gene id: 398580:DSHI_RS09270
uniprot id: A8LML4
names: Similarity
messages: Belongs to the pirin family.

398580:DSHI RS18320
gene id: 398580:DSHI_RS18320
uniprot id: A8LSY6
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

398580:DSHI RS19140
gene id: 398580:DSHI_RS19140
uniprot id: A8LTF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

398580:DSHI RS03135
gene id: 398580:DSHI_RS03135
uniprot id: A8LPP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

398580:DSHI RS05340
gene id: 398580:DSHI_RS05340
uniprot id: A8LSH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS13775
gene id: 398580:DSHI_RS13775
uniprot id: A8LIK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

398580:DSHI RS13645
gene id: 398580:DSHI_RS13645
uniprot id: A8LII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS08625
gene id: 398580:DSHI_RS08625
uniprot id: A8LLQ8
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS01435
gene id: 398580:DSHI_RS01435
uniprot id: A8LM60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

398580:DSHI RS05305
gene id: 398580:DSHI_RS05305
uniprot id: A8LSG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS03120
gene id: 398580:DSHI_RS03120
uniprot id: A8LPN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

398580:DSHI RS14165
gene id: 398580:DSHI_RS14165
uniprot id: A8LJ28
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

398580:DSHI RS01885
gene id: 398580:DSHI_RS01885
uniprot id: A8LMY1
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS09455
gene id: 398580:DSHI_RS09455
uniprot id: A8LN82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

398580:DSHI RS09610
gene id: 398580:DSHI_RS09610
uniprot id: A8LNB5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

398580:DSHI RS13635
gene id: 398580:DSHI_RS13635
uniprot id: A8LIH8
names: Similarity
messages: Belongs to the universal stress protein A family.

398580:DSHI RS16485
gene id: 398580:DSHI_RS16485
uniprot id: A8LMR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

398580:DSHI RS08130
gene id: 398580:DSHI_RS08130
uniprot id: A8LKX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS05900
gene id: 398580:DSHI_RS05900
uniprot id: A8LHV0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

398580:DSHI RS07670
gene id: 398580:DSHI_RS07670
uniprot id: A8LK49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

398580:DSHI RS16100
gene id: 398580:DSHI_RS16100
uniprot id: A8LM00
names: Similarity
messages: Belongs to the Ahb/Nir family.

398580:DSHI RS01185
gene id: 398580:DSHI_RS01185
uniprot id: A8LLH6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

398580:DSHI RS08470
gene id: 398580:DSHI_RS08470
uniprot id: A8LLM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS20665
gene id: 398580:DSHI_RS20665
uniprot id: A8LUB5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

398580:DSHI RS14205
gene id: 398580:DSHI_RS14205
uniprot id: A8LJ36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS16005
gene id: 398580:DSHI_RS16005
uniprot id: A8LLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS13470
gene id: 398580:DSHI_RS13470
uniprot id: A8LI53
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

398580:DSHI RS05830
gene id: 398580:DSHI_RS05830
uniprot id: A8LHT6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.

398580:DSHI RS07965
gene id: 398580:DSHI_RS07965
uniprot id: A8LKU3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

398580:DSHI RS15080
gene id: 398580:DSHI_RS15080
uniprot id: A8LKC3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

398580:DSHI RS12180
gene id: 398580:DSHI_RS12180
uniprot id: A8LS35
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

398580:DSHI RS15365
gene id: 398580:DSHI_RS15365
uniprot id: A8LKH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria (By similarity).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).

398580:DSHI RS13925
gene id: 398580:DSHI_RS13925
uniprot id: A8LIN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

398580:DSHI RS13105
gene id: 398580:DSHI_RS13105
uniprot id: A8LHX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

398580:DSHI RS11190
gene id: 398580:DSHI_RS11190
uniprot id: A8LR14
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS12205
gene id: 398580:DSHI_RS12205
uniprot id: A8LS40
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

398580:DSHI RS01615
gene id: 398580:DSHI_RS01615
uniprot id: A8LM96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

398580:DSHI RS20690
gene id: 398580:DSHI_RS20690
uniprot id: A8LUC0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

398580:DSHI RS00425
gene id: 398580:DSHI_RS00425
uniprot id: A8LKJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

398580:DSHI RS16090
gene id: 398580:DSHI_RS16090
uniprot id: A8LLZ8
names: Similarity
messages: Belongs to the Ahb/Nir family.

398580:DSHI RS11430
gene id: 398580:DSHI_RS11430
uniprot id: A8LR62
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

398580:DSHI RS11140
gene id: 398580:DSHI_RS11140
uniprot id: A8LQQ8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

398580:DSHI RS20555
gene id: 398580:DSHI_RS20555
uniprot id: A8LU92
names: Similarity
messages: Belongs to the RelE toxin family.

398580:DSHI RS02425
gene id: 398580:DSHI_RS02425
uniprot id: A8LNR4
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

398580:DSHI RS18595
gene id: 398580:DSHI_RS18595
uniprot id: A8LT46
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

398580:DSHI RS11925
gene id: 398580:DSHI_RS11925
uniprot id: A8LRP9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS13425
gene id: 398580:DSHI_RS13425
uniprot id: A8LI44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

398580:DSHI RS06420
gene id: 398580:DSHI_RS06420
uniprot id: A8LIE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

398580:DSHI RS09820
gene id: 398580:DSHI_RS09820
uniprot id: A8LNY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

398580:DSHI RS17695
gene id: 398580:DSHI_RS17695
uniprot id: A8LPG4
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS08750
gene id: 398580:DSHI_RS08750
uniprot id: A8LLT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

398580:DSHI RS06365
gene id: 398580:DSHI_RS06365
uniprot id: A8LID6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS05620
gene id: 398580:DSHI_RS05620
uniprot id: A8LHP4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

398580:DSHI RS15740
gene id: 398580:DSHI_RS15740
uniprot id: A8LL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

398580:DSHI RS15265
gene id: 398580:DSHI_RS15265
uniprot id: A8LKF8
names: Subcellular Location Annotation
messages: Cell inner membrane

398580:DSHI RS19890
gene id: 398580:DSHI_RS19890
uniprot id: A8LSX7
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

398580:DSHI RS04230
gene id: 398580:DSHI_RS04230
uniprot id: A8LRC1
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

398580:DSHI RS12025
gene id: 398580:DSHI_RS12025
uniprot id: A8LRR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

398580:DSHI RS08165
gene id: 398580:DSHI_RS08165
uniprot id: A8LKY3
names: Similarity
messages: Belongs to the virb1 family.

398580:DSHI RS06910
gene id: 398580:DSHI_RS06910
uniprot id: A8LIY5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS14550
gene id: 398580:DSHI_RS14550
uniprot id: A8LJJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

398580:DSHI RS05210
gene id: 398580:DSHI_RS05210
uniprot id: A8LSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

398580:DSHI RS14460
gene id: 398580:DSHI_RS14460
uniprot id: A8LJ87
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

398580:DSHI RS04875
gene id: 398580:DSHI_RS04875
uniprot id: A8LRZ2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

398580:DSHI RS08635
gene id: 398580:DSHI_RS08635
uniprot id: A8LLR0
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

398580:DSHI RS07830
gene id: 398580:DSHI_RS07830
uniprot id: A8LK81
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

398580:DSHI RS10410
gene id: 398580:DSHI_RS10410
uniprot id: A8LPS8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS17815
gene id: 398580:DSHI_RS17815
uniprot id: A8LQ13
names: Function
names: Similarity
messages: Belongs to the PufQ family.
messages: Required for bacteriochlorophyll biosynthesis. Directly involved in the assembly of both the B875 and B800-850 pigment-protein complexes.

398580:DSHI RS02745
gene id: 398580:DSHI_RS02745
uniprot id: A8LPG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

398580:DSHI RS06095
gene id: 398580:DSHI_RS06095
uniprot id: A8LI82
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

398580:DSHI RS06660
gene id: 398580:DSHI_RS06660
uniprot id: A8LIT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

398580:DSHI RS06245
gene id: 398580:DSHI_RS06245
uniprot id: A8LIB1
names: Similarity
messages: Belongs to the peptidase M1 family.

398580:DSHI RS12335
gene id: 398580:DSHI_RS12335
uniprot id: A8LS65
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS08615
gene id: 398580:DSHI_RS08615
uniprot id: A8LLQ6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

398580:DSHI RS09200
gene id: 398580:DSHI_RS09200
uniprot id: A8LMK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS20035
gene id: 398580:DSHI_RS20035
uniprot id: A8LU00
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS14400
gene id: 398580:DSHI_RS14400
uniprot id: A8LJ75
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS11560
gene id: 398580:DSHI_RS11560
uniprot id: A8LR88
names: Similarity
messages: Belongs to the RecJ family.

398580:DSHI RS18470
gene id: 398580:DSHI_RS18470
uniprot id: A8LT17
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

398580:DSHI RS01825
gene id: 398580:DSHI_RS01825
uniprot id: A8LMW9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

398580:DSHI RS19335
gene id: 398580:DSHI_RS19335
uniprot id: A8LTJ5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

398580:DSHI RS00935
gene id: 398580:DSHI_RS00935
uniprot id: A8LLC7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

398580:DSHI RS08565
gene id: 398580:DSHI_RS08565
uniprot id: A8LLP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

398580:DSHI RS01300
gene id: 398580:DSHI_RS01300
uniprot id: A8LLK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

398580:DSHI RS09205
gene id: 398580:DSHI_RS09205
uniprot id: A8LMK3
names: Similarity
messages: Belongs to the citrate synthase family.

398580:DSHI RS14910
gene id: 398580:DSHI_RS14910
uniprot id: A8LJR9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

398580:DSHI RS15050
gene id: 398580:DSHI_RS15050
uniprot id: A8LKB7
names: Similarity
messages: Belongs to the GcvT family.

398580:DSHI RS05510
gene id: 398580:DSHI_RS05510
uniprot id: A8LSK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

398580:DSHI RS07440
gene id: 398580:DSHI_RS07440
uniprot id: A8LK04
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

398580:DSHI RS05795
gene id: 398580:DSHI_RS05795
uniprot id: A8LHS9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

398580:DSHI RS11980
gene id: 398580:DSHI_RS11980
uniprot id: A8LRQ9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS06295
gene id: 398580:DSHI_RS06295
uniprot id: A8LIC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

398580:DSHI RS03395
gene id: 398580:DSHI_RS03395
uniprot id: A8LQC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

398580:DSHI RS07200
gene id: 398580:DSHI_RS07200
uniprot id: A8LJD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS05985
gene id: 398580:DSHI_RS05985
uniprot id: A8LHW7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

398580:DSHI RS17500
gene id: 398580:DSHI_RS17500
uniprot id: A8LPC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

398580:DSHI RS01010
gene id: 398580:DSHI_RS01010
uniprot id: A8LLE2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

398580:DSHI RS08695
gene id: 398580:DSHI_RS08695
uniprot id: A8LLS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

398580:DSHI RS13245
gene id: 398580:DSHI_RS13245
uniprot id: A8LI08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

398580:DSHI RS10495
gene id: 398580:DSHI_RS10495
uniprot id: A8LPU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

398580:DSHI RS12250
gene id: 398580:DSHI_RS12250
uniprot id: A8LS49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

398580:DSHI RS17470
gene id: 398580:DSHI_RS17470
uniprot id: A8LPB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

398580:DSHI RS17465
gene id: 398580:DSHI_RS17465
uniprot id: A8LPB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

398580:DSHI RS20445
gene id: 398580:DSHI_RS20445
uniprot id: A8LTF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

398580:DSHI RS14025
gene id: 398580:DSHI_RS14025
uniprot id: A8LJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

398580:DSHI RS11960
gene id: 398580:DSHI_RS11960
uniprot id: A8LRQ5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

398580:DSHI RS14085
gene id: 398580:DSHI_RS14085
uniprot id: A8LJ12
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

398580:DSHI RS03895
gene id: 398580:DSHI_RS03895
uniprot id: A8LQW4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS11955
gene id: 398580:DSHI_RS11955
uniprot id: A8LRQ4
names: Similarity
messages: Belongs to the HesB/IscA family.

398580:DSHI RS05110
gene id: 398580:DSHI_RS05110
uniprot id: A8LSC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

398580:DSHI RS13395
gene id: 398580:DSHI_RS13395
uniprot id: A8LI38
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS09230
gene id: 398580:DSHI_RS09230
uniprot id: A8LMK8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

398580:DSHI RS17390
gene id: 398580:DSHI_RS17390
uniprot id: A8LPA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

398580:DSHI RS11200
gene id: 398580:DSHI_RS11200
uniprot id: A8LR16
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

398580:DSHI RS19065
gene id: 398580:DSHI_RS19065
uniprot id: A8LTE0
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

398580:DSHI RS18740
gene id: 398580:DSHI_RS18740
uniprot id: A8LT73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS16695
gene id: 398580:DSHI_RS16695
uniprot id: A8LMV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

398580:DSHI RS04955
gene id: 398580:DSHI_RS04955
uniprot id: A8LS06
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS05840
gene id: 398580:DSHI_RS05840
uniprot id: A8LHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

398580:DSHI RS09120
gene id: 398580:DSHI_RS09120
uniprot id: A8LMI6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS19145
gene id: 398580:DSHI_RS19145
uniprot id: A8LTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

398580:DSHI RS18290
gene id: 398580:DSHI_RS18290
uniprot id: A8LSY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

398580:DSHI RS17485
gene id: 398580:DSHI_RS17485
uniprot id: A8LPC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS07290
gene id: 398580:DSHI_RS07290
uniprot id: A8LJF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS08160
gene id: 398580:DSHI_RS08160
uniprot id: A8LKY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

398580:DSHI RS14120
gene id: 398580:DSHI_RS14120
uniprot id: A8LJ19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

398580:DSHI RS06875
gene id: 398580:DSHI_RS06875
uniprot id: A8LIX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

398580:DSHI RS03805
gene id: 398580:DSHI_RS03805
uniprot id: A8LQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS15855
gene id: 398580:DSHI_RS15855
uniprot id: A8LLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS21090
gene id: 398580:DSHI_RS21090
uniprot id: A8LUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS02270
gene id: 398580:DSHI_RS02270
uniprot id: A8LN47
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

398580:DSHI RS12210
gene id: 398580:DSHI_RS12210
uniprot id: A8LS41
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

398580:DSHI RS11825
gene id: 398580:DSHI_RS11825
uniprot id: A8LRN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS13895
gene id: 398580:DSHI_RS13895
uniprot id: A8LIM9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

398580:DSHI RS21060
gene id: 398580:DSHI_RS21060
uniprot id: A8LUJ0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

398580:DSHI RS07380
gene id: 398580:DSHI_RS07380
uniprot id: A8LJG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

398580:DSHI RS05665
gene id: 398580:DSHI_RS05665
uniprot id: A8LHQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

398580:DSHI RS09625
gene id: 398580:DSHI_RS09625
uniprot id: A8LNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

398580:DSHI RS06955
gene id: 398580:DSHI_RS06955
uniprot id: A8LIZ4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS00355
gene id: 398580:DSHI_RS00355
uniprot id: A8LJZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

398580:DSHI RS07100
gene id: 398580:DSHI_RS07100
uniprot id: A8LJB5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

398580:DSHI RS16955
gene id: 398580:DSHI_RS16955
uniprot id: A8LNI4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

398580:DSHI RS00010
gene id: 398580:DSHI_RS00010
uniprot id: A8LJS5
names: Similarity
messages: Belongs to the glutamate synthase family.

398580:DSHI RS06060
gene id: 398580:DSHI_RS06060
uniprot id: A8LI75
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

398580:DSHI RS12280
gene id: 398580:DSHI_RS12280
uniprot id: A8LS54
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

398580:DSHI RS07140
gene id: 398580:DSHI_RS07140
uniprot id: A8LJC3
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS19060
gene id: 398580:DSHI_RS19060
uniprot id: A8LTD9
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

398580:DSHI RS09315
gene id: 398580:DSHI_RS09315
uniprot id: A8LMM2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

398580:DSHI RS17480
gene id: 398580:DSHI_RS17480
uniprot id: A8LPC0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

398580:DSHI RS04330
gene id: 398580:DSHI_RS04330
uniprot id: A8LRE1
names: Similarity
messages: Belongs to the ArsC family.

398580:DSHI RS05645
gene id: 398580:DSHI_RS05645
uniprot id: A8LHP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

398580:DSHI RS09475
gene id: 398580:DSHI_RS09475
uniprot id: A8LN86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS13415
gene id: 398580:DSHI_RS13415
uniprot id: A8LI42
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

398580:DSHI RS05575
gene id: 398580:DSHI_RS05575
uniprot id: A8LHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS16415
gene id: 398580:DSHI_RS16415
uniprot id: A8LMP8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS08200
gene id: 398580:DSHI_RS08200
uniprot id: A8LKZ0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

398580:DSHI RS08305
gene id: 398580:DSHI_RS08305
uniprot id: A8LL09
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

398580:DSHI RS19155
gene id: 398580:DSHI_RS19155
uniprot id: A8LTF9
names: Subcellular Location Annotation
messages: Cell inner membrane

398580:DSHI RS13710
gene id: 398580:DSHI_RS13710
uniprot id: A8LIJ2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

398580:DSHI RS18490
gene id: 398580:DSHI_RS18490
uniprot id: A8LT21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

398580:DSHI RS16730
gene id: 398580:DSHI_RS16730
uniprot id: A8LMV9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS17810
gene id: 398580:DSHI_RS17810
uniprot id: A8LQ12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

398580:DSHI RS05190
gene id: 398580:DSHI_RS05190
uniprot id: A8LSE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

398580:DSHI RS16015
gene id: 398580:DSHI_RS16015
uniprot id: A8LLY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS12135
gene id: 398580:DSHI_RS12135
uniprot id: A8LRT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

398580:DSHI RS00610
gene id: 398580:DSHI_RS00610
uniprot id: A8LKM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS10280
gene id: 398580:DSHI_RS10280
uniprot id: A8LPQ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS12660
gene id: 398580:DSHI_RS12660
uniprot id: A8LSM4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS07635
gene id: 398580:DSHI_RS07635
uniprot id: A8LK42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

398580:DSHI RS01285
gene id: 398580:DSHI_RS01285
uniprot id: A8LLJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

398580:DSHI RS05415
gene id: 398580:DSHI_RS05415
uniprot id: A8LSI6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS08970
gene id: 398580:DSHI_RS08970
uniprot id: A8LMF9
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

398580:DSHI RS19830
gene id: 398580:DSHI_RS19830
uniprot id: A8LSW4
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS17660
gene id: 398580:DSHI_RS17660
uniprot id: A8LPF7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

398580:DSHI RS15860
gene id: 398580:DSHI_RS15860
uniprot id: A8LLV2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS14060
gene id: 398580:DSHI_RS14060
uniprot id: A8LJ07
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

398580:DSHI RS15255
gene id: 398580:DSHI_RS15255
uniprot id: A8LKF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

398580:DSHI RS04240
gene id: 398580:DSHI_RS04240
uniprot id: A8LRC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

398580:DSHI RS06350
gene id: 398580:DSHI_RS06350
uniprot id: A8LID3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

398580:DSHI RS17575
gene id: 398580:DSHI_RS17575
uniprot id: A8LPE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

398580:DSHI RS19935
gene id: 398580:DSHI_RS19935
uniprot id: A8LSY6
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

398580:DSHI RS00315
gene id: 398580:DSHI_RS00315
uniprot id: A8LJY9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

398580:DSHI RS05195
gene id: 398580:DSHI_RS05195
uniprot id: A8LSE2
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

398580:DSHI RS18155
gene id: 398580:DSHI_RS18155
uniprot id: A8LQ81
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

398580:DSHI RS03785
gene id: 398580:DSHI_RS03785
uniprot id: A8LQU2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

398580:DSHI RS11275
gene id: 398580:DSHI_RS11275
uniprot id: A8LR31
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

398580:DSHI RS20390
gene id: 398580:DSHI_RS20390
uniprot id: A8LTE0
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

398580:DSHI RS06845
gene id: 398580:DSHI_RS06845
uniprot id: A8LIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

398580:DSHI RS01085
gene id: 398580:DSHI_RS01085
uniprot id: A8LLF7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

398580:DSHI RS07690
gene id: 398580:DSHI_RS07690
uniprot id: A8LK53
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

398580:DSHI RS16505
gene id: 398580:DSHI_RS16505
uniprot id: A8LMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

398580:DSHI RS14230
gene id: 398580:DSHI_RS14230
uniprot id: A8LJ41
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

398580:DSHI RS02720
gene id: 398580:DSHI_RS02720
uniprot id: A8LNX5
names: Similarity
messages: Belongs to the FGGY kinase family.

398580:DSHI RS14625
gene id: 398580:DSHI_RS14625
uniprot id: A8LJL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

398580:DSHI RS17785
gene id: 398580:DSHI_RS17785
uniprot id: A8LQ07
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

398580:DSHI RS07910
gene id: 398580:DSHI_RS07910
uniprot id: A8LKT2
names: Similarity
messages: Belongs to the hyi family.

398580:DSHI RS10860
gene id: 398580:DSHI_RS10860
uniprot id: A8LQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

398580:DSHI RS04675
gene id: 398580:DSHI_RS04675
uniprot id: A8LRV2
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

398580:DSHI RS06215
gene id: 398580:DSHI_RS06215
uniprot id: A8LIA5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

398580:DSHI RS20980
gene id: 398580:DSHI_RS20980
uniprot id: A8LUH4
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS09520
gene id: 398580:DSHI_RS09520
uniprot id: A8LN96
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

398580:DSHI RS07955
gene id: 398580:DSHI_RS07955
uniprot id: A8LKU1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

398580:DSHI RS01655
gene id: 398580:DSHI_RS01655
uniprot id: A8LMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

398580:DSHI RS11225
gene id: 398580:DSHI_RS11225
uniprot id: A8LR21
names: Similarity
messages: Belongs to the peptidase S13 family.

398580:DSHI RS04965
gene id: 398580:DSHI_RS04965
uniprot id: A8LS08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS05370
gene id: 398580:DSHI_RS05370
uniprot id: A8LSH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

398580:DSHI RS20880
gene id: 398580:DSHI_RS20880
uniprot id: A8LUF4
names: Similarity
messages: Belongs to the MipA/OmpV family.

398580:DSHI RS16460
gene id: 398580:DSHI_RS16460
uniprot id: A8LMQ7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

398580:DSHI RS10265
gene id: 398580:DSHI_RS10265
uniprot id: A8LPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS01570
gene id: 398580:DSHI_RS01570
uniprot id: A8LM87
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

398580:DSHI RS15660
gene id: 398580:DSHI_RS15660
uniprot id: A8LL73
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

398580:DSHI RS10985
gene id: 398580:DSHI_RS10985
uniprot id: A8LQM8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

398580:DSHI RS01685
gene id: 398580:DSHI_RS01685
uniprot id: A8LMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS15280
gene id: 398580:DSHI_RS15280
uniprot id: A8LKG1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

398580:DSHI RS06560
gene id: 398580:DSHI_RS06560
uniprot id: A8LIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

398580:DSHI RS19525
gene id: 398580:DSHI_RS19525
uniprot id: A8LTN1
names: Similarity
messages: Belongs to the peptidase S1B family.

398580:DSHI RS07570
gene id: 398580:DSHI_RS07570
uniprot id: A8LK29
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS13125
gene id: 398580:DSHI_RS13125
uniprot id: A8LHY1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

398580:DSHI RS21100
gene id: 398580:DSHI_RS21100
uniprot id: A8LUJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS05810
gene id: 398580:DSHI_RS05810
uniprot id: A8LHT2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

398580:DSHI RS10835
gene id: 398580:DSHI_RS10835
uniprot id: A8LQJ8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

398580:DSHI RS07585
gene id: 398580:DSHI_RS07585
uniprot id: A8LK32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS05145
gene id: 398580:DSHI_RS05145
uniprot id: A8LSD2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS06760
gene id: 398580:DSHI_RS06760
uniprot id: A8LIV5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS20650
gene id: 398580:DSHI_RS20650
uniprot id: A8LUB2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

398580:DSHI RS17525
gene id: 398580:DSHI_RS17525
uniprot id: A8LPD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

398580:DSHI RS18185
gene id: 398580:DSHI_RS18185
uniprot id: A8LQR9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

398580:DSHI RS19590
gene id: 398580:DSHI_RS19590
uniprot id: A8LTP6
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

398580:DSHI RS01015
gene id: 398580:DSHI_RS01015
uniprot id: A8LLE3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS17725
gene id: 398580:DSHI_RS17725
uniprot id: A8LPZ5
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

398580:DSHI RS17425
gene id: 398580:DSHI_RS17425
uniprot id: A8LPA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

398580:DSHI RS02205
gene id: 398580:DSHI_RS02205
uniprot id: A8LN35
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS02625
gene id: 398580:DSHI_RS02625
uniprot id: A8LNV6
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS02895
gene id: 398580:DSHI_RS02895
uniprot id: A8LPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

398580:DSHI RS01480
gene id: 398580:DSHI_RS01480
uniprot id: A8LM69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

398580:DSHI RS08170
gene id: 398580:DSHI_RS08170
uniprot id: A8LKY4
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

398580:DSHI RS11125
gene id: 398580:DSHI_RS11125
uniprot id: A8LQQ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

398580:DSHI RS16095
gene id: 398580:DSHI_RS16095
uniprot id: A8LLZ9
names: Similarity
messages: Belongs to the Ahb/Nir family.

398580:DSHI RS09915
gene id: 398580:DSHI_RS09915
uniprot id: A8LP04
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS05220
gene id: 398580:DSHI_RS05220
uniprot id: A8LSE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS21575
gene id: 398580:DSHI_RS21575
uniprot id: A8LUI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS17475
gene id: 398580:DSHI_RS17475
uniprot id: A8LPB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

398580:DSHI RS09220
gene id: 398580:DSHI_RS09220
uniprot id: A8LMK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

398580:DSHI RS12270
gene id: 398580:DSHI_RS12270
uniprot id: A8LS52
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

398580:DSHI RS19375
gene id: 398580:DSHI_RS19375
uniprot id: A8LTK3
names: Similarity
messages: Belongs to the TPP enzyme family.

398580:DSHI RS01440
gene id: 398580:DSHI_RS01440
uniprot id: A8LM61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

398580:DSHI RS16115
gene id: 398580:DSHI_RS16115
uniprot id: A8LM03
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

398580:DSHI RS15430
gene id: 398580:DSHI_RS15430
uniprot id: A8LL25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

398580:DSHI RS17515
gene id: 398580:DSHI_RS17515
uniprot id: A8LPC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

398580:DSHI RS19210
gene id: 398580:DSHI_RS19210
uniprot id: A8LTH0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS00175
gene id: 398580:DSHI_RS00175
uniprot id: A8LJV9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

398580:DSHI RS04905
gene id: 398580:DSHI_RS04905
uniprot id: A8LRZ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS19850
gene id: 398580:DSHI_RS19850
uniprot id: A8LSW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

398580:DSHI RS19220
gene id: 398580:DSHI_RS19220
uniprot id: A8LTH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS10555
gene id: 398580:DSHI_RS10555
uniprot id: A8LPV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS08650
gene id: 398580:DSHI_RS08650
uniprot id: A8LLR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

398580:DSHI RS06375
gene id: 398580:DSHI_RS06375
uniprot id: A8LID8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS19370
gene id: 398580:DSHI_RS19370
uniprot id: A8LTK2
names: Similarity
messages: Belongs to the Dps family.

398580:DSHI RS12465
gene id: 398580:DSHI_RS12465
uniprot id: A8LS91
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

398580:DSHI RS05120
gene id: 398580:DSHI_RS05120
uniprot id: A8LSC7
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS02580
gene id: 398580:DSHI_RS02580
uniprot id: A8LNU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS00775
gene id: 398580:DSHI_RS00775
uniprot id: A8LKR2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS02780
gene id: 398580:DSHI_RS02780
uniprot id: A8LPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS04335
gene id: 398580:DSHI_RS04335
uniprot id: A8LRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

398580:DSHI RS18455
gene id: 398580:DSHI_RS18455
uniprot id: A8LT14
names: Similarity
messages: Belongs to the GSP E family.

398580:DSHI RS02675
gene id: 398580:DSHI_RS02675
uniprot id: A8LNW6
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS00270
gene id: 398580:DSHI_RS00270
uniprot id: A8LJY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

398580:DSHI RS09010
gene id: 398580:DSHI_RS09010
uniprot id: A8LMG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

398580:DSHI RS13250
gene id: 398580:DSHI_RS13250
uniprot id: A8LI09
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

398580:DSHI RS11280
gene id: 398580:DSHI_RS11280
uniprot id: A8LR32
names: Subcellular Location Annotation
messages: Cytoplasm

398580:DSHI RS14830
gene id: 398580:DSHI_RS14830
uniprot id: A8LJQ3
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS08270
gene id: 398580:DSHI_RS08270
uniprot id: A8LL03
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS12400
gene id: 398580:DSHI_RS12400
uniprot id: A8LS78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

398580:DSHI RS06145
gene id: 398580:DSHI_RS06145
uniprot id: A8LI91
names: Similarity
messages: Belongs to the BolA/IbaG family.

398580:DSHI RS13365
gene id: 398580:DSHI_RS13365
uniprot id: A8LI32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS22485
gene id: 398580:DSHI_RS22485
uniprot id: A8LSH3
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

398580:DSHI RS09705
gene id: 398580:DSHI_RS09705
uniprot id: A8LND3
names: Subcellular Location Annotation
messages: Periplasm

398580:DSHI RS21125
gene id: 398580:DSHI_RS21125
uniprot id: A8LUK3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

398580:DSHI RS04205
gene id: 398580:DSHI_RS04205
uniprot id: A8LRB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS04055
gene id: 398580:DSHI_RS04055
uniprot id: A8LQZ5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

398580:DSHI RS18135
gene id: 398580:DSHI_RS18135
uniprot id: A8LQ77
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

398580:DSHI RS17970
gene id: 398580:DSHI_RS17970
uniprot id: A8LQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

398580:DSHI RS07260
gene id: 398580:DSHI_RS07260
uniprot id: A8LJE5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

398580:DSHI RS09445
gene id: 398580:DSHI_RS09445
uniprot id: A8LN80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

398580:DSHI RS18050
gene id: 398580:DSHI_RS18050
uniprot id: A8LQ60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

398580:DSHI RS15875
gene id: 398580:DSHI_RS15875
uniprot id: A8LLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS02775
gene id: 398580:DSHI_RS02775
uniprot id: A8LPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS07250
gene id: 398580:DSHI_RS07250
uniprot id: A8LJE3
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS09330
gene id: 398580:DSHI_RS09330
uniprot id: A8LN57
names: Similarity
messages: Belongs to the TPP enzyme family.

398580:DSHI RS08620
gene id: 398580:DSHI_RS08620
uniprot id: A8LLQ7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

398580:DSHI RS14890
gene id: 398580:DSHI_RS14890
uniprot id: A8LJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

398580:DSHI RS20905
gene id: 398580:DSHI_RS20905
uniprot id: A8LUF9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS08820
gene id: 398580:DSHI_RS08820
uniprot id: A8LLU6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

398580:DSHI RS19940
gene id: 398580:DSHI_RS19940
uniprot id: A8LSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

398580:DSHI RS08505
gene id: 398580:DSHI_RS08505
uniprot id: A8LLN5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

398580:DSHI RS11170
gene id: 398580:DSHI_RS11170
uniprot id: A8LQR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

398580:DSHI RS18010
gene id: 398580:DSHI_RS18010
uniprot id: A8LQ52
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

398580:DSHI RS00650
gene id: 398580:DSHI_RS00650
uniprot id: A8LKN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

398580:DSHI RS09240
gene id: 398580:DSHI_RS09240
uniprot id: A8LML0
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS08410
gene id: 398580:DSHI_RS08410
uniprot id: A8LLL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS01505
gene id: 398580:DSHI_RS01505
uniprot id: A8LM74
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

398580:DSHI RS15475
gene id: 398580:DSHI_RS15475
uniprot id: A8LL34
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

398580:DSHI RS20020
gene id: 398580:DSHI_RS20020
uniprot id: A8LTZ6
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

398580:DSHI RS12420
gene id: 398580:DSHI_RS12420
uniprot id: A8LS82
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

398580:DSHI RS07935
gene id: 398580:DSHI_RS07935
uniprot id: A8LKT7
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS19295
gene id: 398580:DSHI_RS19295
uniprot id: A8LTI7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

398580:DSHI RS10980
gene id: 398580:DSHI_RS10980
uniprot id: A8LQM7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

398580:DSHI RS18640
gene id: 398580:DSHI_RS18640
uniprot id: A8LT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

398580:DSHI RS09180
gene id: 398580:DSHI_RS09180
uniprot id: A8LMJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

398580:DSHI RS07895
gene id: 398580:DSHI_RS07895
uniprot id: A8LKS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

398580:DSHI RS08105
gene id: 398580:DSHI_RS08105
uniprot id: A8LKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

398580:DSHI RS12075
gene id: 398580:DSHI_RS12075
uniprot id: A8LRS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

398580:DSHI RS16665
gene id: 398580:DSHI_RS16665
uniprot id: A8LMU6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

398580:DSHI RS04280
gene id: 398580:DSHI_RS04280
uniprot id: A8LRD1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

398580:DSHI RS06595
gene id: 398580:DSHI_RS06595
uniprot id: A8LIS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

398580:DSHI RS05165
gene id: 398580:DSHI_RS05165
uniprot id: A8LSD6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

398580:DSHI RS01000
gene id: 398580:DSHI_RS01000
uniprot id: A8LLE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS10765
gene id: 398580:DSHI_RS10765
uniprot id: A8LQI4
names: Similarity
messages: Belongs to the GcvT family.

398580:DSHI RS01465
gene id: 398580:DSHI_RS01465
uniprot id: A8LM66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

398580:DSHI RS08755
gene id: 398580:DSHI_RS08755
uniprot id: A8LLT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

398580:DSHI RS04025
gene id: 398580:DSHI_RS04025
uniprot id: A8LQY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

398580:DSHI RS06605
gene id: 398580:DSHI_RS06605
uniprot id: A8LIS4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

398580:DSHI RS10970
gene id: 398580:DSHI_RS10970
uniprot id: A8LQM5
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

398580:DSHI RS09365
gene id: 398580:DSHI_RS09365
uniprot id: A8LN64
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS08950
gene id: 398580:DSHI_RS08950
uniprot id: A8LMF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

398580:DSHI RS08380
gene id: 398580:DSHI_RS08380
uniprot id: A8LLL0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

398580:DSHI RS11860
gene id: 398580:DSHI_RS11860
uniprot id: A8LRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

398580:DSHI RS00450
gene id: 398580:DSHI_RS00450
uniprot id: A8LKJ8
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

398580:DSHI RS06650
gene id: 398580:DSHI_RS06650
uniprot id: A8LIT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

398580:DSHI RS07865
gene id: 398580:DSHI_RS07865
uniprot id: A8LK88
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

398580:DSHI RS18130
gene id: 398580:DSHI_RS18130
uniprot id: A8LQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

398580:DSHI RS07825
gene id: 398580:DSHI_RS07825
uniprot id: A8LK80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

398580:DSHI RS08115
gene id: 398580:DSHI_RS08115
uniprot id: A8LKX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

398580:DSHI RS04705
gene id: 398580:DSHI_RS04705
uniprot id: A8LRV8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

398580:DSHI RS06035
gene id: 398580:DSHI_RS06035
uniprot id: A8LI70
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

398580:DSHI RS03640
gene id: 398580:DSHI_RS03640
uniprot id: A8LQH0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS09385
gene id: 398580:DSHI_RS09385
uniprot id: A8LN67
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

398580:DSHI RS14710
gene id: 398580:DSHI_RS14710
uniprot id: A8LJM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex alpha subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components.

398580:DSHI RS10085
gene id: 398580:DSHI_RS10085
uniprot id: A8LP36
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS13640
gene id: 398580:DSHI_RS13640
uniprot id: A8LIH9
names: Subcellular Location Annotation
messages: Periplasm

398580:DSHI RS16600
gene id: 398580:DSHI_RS16600
uniprot id: A8LMT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

398580:DSHI RS16615
gene id: 398580:DSHI_RS16615
uniprot id: A8LMT6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

398580:DSHI RS11910
gene id: 398580:DSHI_RS11910
uniprot id: A8LRP6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

398580:DSHI RS06780
gene id: 398580:DSHI_RS06780
uniprot id: A8LIV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS02695
gene id: 398580:DSHI_RS02695
uniprot id: A8LNX0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

398580:DSHI RS03730
gene id: 398580:DSHI_RS03730
uniprot id: A8LQT1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

398580:DSHI RS19215
gene id: 398580:DSHI_RS19215
uniprot id: A8LTH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS15030
gene id: 398580:DSHI_RS15030
uniprot id: A8LKB3
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS05435
gene id: 398580:DSHI_RS05435
uniprot id: A8LSJ0
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS05135
gene id: 398580:DSHI_RS05135
uniprot id: A8LSD0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

398580:DSHI RS02050
gene id: 398580:DSHI_RS02050
uniprot id: A8LN05
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Binds crRNA and tracrRNA.

398580:DSHI RS03735
gene id: 398580:DSHI_RS03735
uniprot id: A8LQT2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS00875
gene id: 398580:DSHI_RS00875
uniprot id: A8LLB5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

398580:DSHI RS02220
gene id: 398580:DSHI_RS02220
uniprot id: A8LN38
names: Similarity
messages: Belongs to the carbamate kinase family.

398580:DSHI RS05885
gene id: 398580:DSHI_RS05885
uniprot id: A8LHU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

398580:DSHI RS17130
gene id: 398580:DSHI_RS17130
uniprot id: A8LNM1
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS11110
gene id: 398580:DSHI_RS11110
uniprot id: A8LQQ2
names: Similarity
messages: Belongs to the fabD family.

398580:DSHI RS00575
gene id: 398580:DSHI_RS00575
uniprot id: A8LKM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS10455
gene id: 398580:DSHI_RS10455
uniprot id: A8LPT7
names: Similarity
messages: Belongs to the histone deacetylase family.

398580:DSHI RS09855
gene id: 398580:DSHI_RS09855
uniprot id: A8LNZ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

398580:DSHI RS14945
gene id: 398580:DSHI_RS14945
uniprot id: A8LK96
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

398580:DSHI RS03555
gene id: 398580:DSHI_RS03555
uniprot id: A8LQF5
names: Function
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

398580:DSHI RS06655
gene id: 398580:DSHI_RS06655
uniprot id: A8LIT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS19620
gene id: 398580:DSHI_RS19620
uniprot id: A8LTQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

398580:DSHI RS01625
gene id: 398580:DSHI_RS01625
uniprot id: A8LM98
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

398580:DSHI RS13210
gene id: 398580:DSHI_RS13210
uniprot id: A8LI01
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS18215
gene id: 398580:DSHI_RS18215
uniprot id: A8LSW4
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS07360
gene id: 398580:DSHI_RS07360
uniprot id: A8LJG5
names: Similarity
messages: Belongs to the universal stress protein A family.

398580:DSHI RS06065
gene id: 398580:DSHI_RS06065
uniprot id: A8LI76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS05020
gene id: 398580:DSHI_RS05020
uniprot id: A8LS17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

398580:DSHI RS06430
gene id: 398580:DSHI_RS06430
uniprot id: A8LIE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

398580:DSHI RS11555
gene id: 398580:DSHI_RS11555
uniprot id: A8LR87
names: Similarity
messages: Belongs to the FBPase class 2 family.

398580:DSHI RS15580
gene id: 398580:DSHI_RS15580
uniprot id: A8LL57
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

398580:DSHI RS03370
gene id: 398580:DSHI_RS03370
uniprot id: A8LQB9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS06550
gene id: 398580:DSHI_RS06550
uniprot id: A8LIR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

398580:DSHI RS01515
gene id: 398580:DSHI_RS01515
uniprot id: A8LM76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

398580:DSHI RS08610
gene id: 398580:DSHI_RS08610
uniprot id: A8LLQ5
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

398580:DSHI RS17460
gene id: 398580:DSHI_RS17460
uniprot id: A8LPB6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

398580:DSHI RS17890
gene id: 398580:DSHI_RS17890
uniprot id: A8LQ28
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

398580:DSHI RS17075
gene id: 398580:DSHI_RS17075
uniprot id: A8LNK9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

398580:DSHI RS02250
gene id: 398580:DSHI_RS02250
uniprot id: A8LN43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

398580:DSHI RS07515
gene id: 398580:DSHI_RS07515
uniprot id: A8LK19
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

398580:DSHI RS20045
gene id: 398580:DSHI_RS20045
uniprot id: A8LU02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

398580:DSHI RS05155
gene id: 398580:DSHI_RS05155
uniprot id: A8LSD4
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS12630
gene id: 398580:DSHI_RS12630
uniprot id: A8LSL9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

398580:DSHI RS04290
gene id: 398580:DSHI_RS04290
uniprot id: A8LRD3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS05650
gene id: 398580:DSHI_RS05650
uniprot id: A8LHQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

398580:DSHI RS06470
gene id: 398580:DSHI_RS06470
uniprot id: A8LIF7
names: Similarity
messages: Belongs to the TPP enzyme family.

398580:DSHI RS01080
gene id: 398580:DSHI_RS01080
uniprot id: A8LLF6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

398580:DSHI RS15870
gene id: 398580:DSHI_RS15870
uniprot id: A8LLV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS07355
gene id: 398580:DSHI_RS07355
uniprot id: A8LJG4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

398580:DSHI RS11790
gene id: 398580:DSHI_RS11790
uniprot id: A8LRM3
names: Similarity
messages: Belongs to the DNA photolyase family.

398580:DSHI RS13175
gene id: 398580:DSHI_RS13175
uniprot id: A8LHZ4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

398580:DSHI RS13450
gene id: 398580:DSHI_RS13450
uniprot id: A8LI49
names: Subcellular Location Annotation
messages: Mitochondrion

398580:DSHI RS05965
gene id: 398580:DSHI_RS05965
uniprot id: A8LHW3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS18350
gene id: 398580:DSHI_RS18350
uniprot id: A8LSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

398580:DSHI RS03350
gene id: 398580:DSHI_RS03350
uniprot id: A8LQB5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

398580:DSHI RS15845
gene id: 398580:DSHI_RS15845
uniprot id: A8LLA9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS00090
gene id: 398580:DSHI_RS00090
uniprot id: A8LJU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS17415
gene id: 398580:DSHI_RS17415
uniprot id: A8LPA7
names: Similarity
messages: Belongs to the thioredoxin family.

398580:DSHI RS17555
gene id: 398580:DSHI_RS17555
uniprot id: A8LPD6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

398580:DSHI RS20680
gene id: 398580:DSHI_RS20680
uniprot id: A8LUB8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

398580:DSHI RS11465
gene id: 398580:DSHI_RS11465
uniprot id: A8LR69
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

398580:DSHI RS14960
gene id: 398580:DSHI_RS14960
uniprot id: A8LK99
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

398580:DSHI RS05680
gene id: 398580:DSHI_RS05680
uniprot id: A8LHQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

398580:DSHI RS03820
gene id: 398580:DSHI_RS03820
uniprot id: A8LQU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

398580:DSHI RS18295
gene id: 398580:DSHI_RS18295
uniprot id: A8LSY1
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS10360
gene id: 398580:DSHI_RS10360
uniprot id: A8LPR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS04460
gene id: 398580:DSHI_RS04460
uniprot id: A8LRG7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

398580:DSHI RS08285
gene id: 398580:DSHI_RS08285
uniprot id: A8LL06
names: Similarity
messages: Belongs to the UPF0145 family.

398580:DSHI RS08310
gene id: 398580:DSHI_RS08310
uniprot id: A8LL10
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

398580:DSHI RS20995
gene id: 398580:DSHI_RS20995
uniprot id: A8LUH7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

398580:DSHI RS13480
gene id: 398580:DSHI_RS13480
uniprot id: A8LI55
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS08800
gene id: 398580:DSHI_RS08800
uniprot id: A8LLU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS07010
gene id: 398580:DSHI_RS07010
uniprot id: A8LJ97
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

398580:DSHI RS01800
gene id: 398580:DSHI_RS01800
uniprot id: A8LMD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

398580:DSHI RS01175
gene id: 398580:DSHI_RS01175
uniprot id: A8LLH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

398580:DSHI RS07900
gene id: 398580:DSHI_RS07900
uniprot id: A8LKT0
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

398580:DSHI RS15065
gene id: 398580:DSHI_RS15065
uniprot id: A8LKC0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

398580:DSHI RS12125
gene id: 398580:DSHI_RS12125
uniprot id: A8LRT6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

398580:DSHI RS06730
gene id: 398580:DSHI_RS06730
uniprot id: A8LIU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

398580:DSHI RS02210
gene id: 398580:DSHI_RS02210
uniprot id: A8LN36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

398580:DSHI RS13780
gene id: 398580:DSHI_RS13780
uniprot id: A8LIK6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

398580:DSHI RS07510
gene id: 398580:DSHI_RS07510
uniprot id: A8LK18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

398580:DSHI RS16805
gene id: 398580:DSHI_RS16805
uniprot id: A8LNF5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

398580:DSHI RS03800
gene id: 398580:DSHI_RS03800
uniprot id: A8LQU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

398580:DSHI RS01710
gene id: 398580:DSHI_RS01710
uniprot id: A8LMB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

398580:DSHI RS10875
gene id: 398580:DSHI_RS10875
uniprot id: A8LQK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

398580:DSHI RS13510
gene id: 398580:DSHI_RS13510
uniprot id: A8LI61
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

398580:DSHI RS20050
gene id: 398580:DSHI_RS20050
uniprot id: A8LU03
names: Similarity
messages: Belongs to the GSP E family.

398580:DSHI RS08910
gene id: 398580:DSHI_RS08910
uniprot id: A8LME7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS04695
gene id: 398580:DSHI_RS04695
uniprot id: A8LRV6
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS18825
gene id: 398580:DSHI_RS18825
uniprot id: A8LT90
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS17835
gene id: 398580:DSHI_RS17835
uniprot id: A8LQ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Cellular chromatophore membrane
messages: Membrane
messages: Reaction center is composed of four bacteriochlorophylls, two bacteriopheophytins, two ubiquinones, one iron, and highly hydrophobic polypeptide chains.
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

398580:DSHI RS14540
gene id: 398580:DSHI_RS14540
uniprot id: A8LJJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS01360
gene id: 398580:DSHI_RS01360
uniprot id: A8LM45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

398580:DSHI RS17620
gene id: 398580:DSHI_RS17620
uniprot id: A8LPE9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

398580:DSHI RS19085
gene id: 398580:DSHI_RS19085
uniprot id: A8LTE4
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS18065
gene id: 398580:DSHI_RS18065
uniprot id: A8LQ63
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

398580:DSHI RS10365
gene id: 398580:DSHI_RS10365
uniprot id: A8LPR9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family. HpsN subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD-dependent oxidation of (R)-2,3-dihydroxypropane-1-sulfonate to (R)-3-sulfolactate.

398580:DSHI RS00155
gene id: 398580:DSHI_RS00155
uniprot id: A8LJV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

398580:DSHI RS08075
gene id: 398580:DSHI_RS08075
uniprot id: A8LKW5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

398580:DSHI RS07600
gene id: 398580:DSHI_RS07600
uniprot id: A8LK35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

398580:DSHI RS02305
gene id: 398580:DSHI_RS02305
uniprot id: A8LN54
names: Function
names: Similarity
messages: Belongs to the PqqA family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.

398580:DSHI RS08135
gene id: 398580:DSHI_RS08135
uniprot id: A8LKX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS10900
gene id: 398580:DSHI_RS10900
uniprot id: A8LQL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS14980
gene id: 398580:DSHI_RS14980
uniprot id: A8LKA3
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

398580:DSHI RS14895
gene id: 398580:DSHI_RS14895
uniprot id: A8LJR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12) (By similarity).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

398580:DSHI RS03840
gene id: 398580:DSHI_RS03840
uniprot id: A8LQV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

398580:DSHI RS07315
gene id: 398580:DSHI_RS07315
uniprot id: A8LJF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS20385
gene id: 398580:DSHI_RS20385
uniprot id: A8LTD9
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

398580:DSHI RS08890
gene id: 398580:DSHI_RS08890
uniprot id: A8LME3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS05820
gene id: 398580:DSHI_RS05820
uniprot id: A8LHT4
names: Similarity
messages: Belongs to the peptidase U62 family.

398580:DSHI RS13455
gene id: 398580:DSHI_RS13455
uniprot id: A8LI50
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

398580:DSHI RS12830
gene id: 398580:DSHI_RS12830
uniprot id: A8LSQ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS05245
gene id: 398580:DSHI_RS05245
uniprot id: A8LSF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

398580:DSHI RS05390
gene id: 398580:DSHI_RS05390
uniprot id: A8LSI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS11145
gene id: 398580:DSHI_RS11145
uniprot id: A8LQQ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

398580:DSHI RS03740
gene id: 398580:DSHI_RS03740
uniprot id: A8LQT3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS00825
gene id: 398580:DSHI_RS00825
uniprot id: A8LKS2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS14955
gene id: 398580:DSHI_RS14955
uniprot id: A8LK98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

398580:DSHI RS18750
gene id: 398580:DSHI_RS18750
uniprot id: A8LT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS00685
gene id: 398580:DSHI_RS00685
uniprot id: A8LKP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

398580:DSHI RS02810
gene id: 398580:DSHI_RS02810
uniprot id: A8LPH8
names: Similarity
messages: Belongs to the FGGY kinase family.

398580:DSHI RS14015
gene id: 398580:DSHI_RS14015
uniprot id: A8LIZ8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

398580:DSHI RS17270
gene id: 398580:DSHI_RS17270
uniprot id: A8LP78
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

398580:DSHI RS01545
gene id: 398580:DSHI_RS01545
uniprot id: A8LM82
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

398580:DSHI RS10815
gene id: 398580:DSHI_RS10815
uniprot id: A8LQJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS16490
gene id: 398580:DSHI_RS16490
uniprot id: A8LMR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

398580:DSHI RS16205
gene id: 398580:DSHI_RS16205
uniprot id: A8LM21
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS06165
gene id: 398580:DSHI_RS06165
uniprot id: A8LI95
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

398580:DSHI RS05750
gene id: 398580:DSHI_RS05750
uniprot id: A8LHS0
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS01110
gene id: 398580:DSHI_RS01110
uniprot id: A8LLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

398580:DSHI RS13565
gene id: 398580:DSHI_RS13565
uniprot id: A8LIG5
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

398580:DSHI RS06345
gene id: 398580:DSHI_RS06345
uniprot id: A8LID2
names: Similarity
messages: Belongs to the IlvD/Edd family.

398580:DSHI RS01820
gene id: 398580:DSHI_RS01820
uniprot id: A8LMW8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

398580:DSHI RS11665
gene id: 398580:DSHI_RS11665
uniprot id: A8LRJ9
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

398580:DSHI RS00655
gene id: 398580:DSHI_RS00655
uniprot id: A8LKN8
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

398580:DSHI RS11995
gene id: 398580:DSHI_RS11995
uniprot id: A8LRR2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS04095
gene id: 398580:DSHI_RS04095
uniprot id: A8LR03
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

398580:DSHI RS10625
gene id: 398580:DSHI_RS10625
uniprot id: A8LPX1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS11105
gene id: 398580:DSHI_RS11105
uniprot id: A8LQQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

398580:DSHI RS19965
gene id: 398580:DSHI_RS19965
uniprot id: A8LSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

398580:DSHI RS14600
gene id: 398580:DSHI_RS14600
uniprot id: A8LJK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

398580:DSHI RS18285
gene id: 398580:DSHI_RS18285
uniprot id: A8LSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS00160
gene id: 398580:DSHI_RS00160
uniprot id: A8LJV6
names: Similarity
messages: Belongs to the UPF0434 family.

398580:DSHI RS10350
gene id: 398580:DSHI_RS10350
uniprot id: A8LPR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS09435
gene id: 398580:DSHI_RS09435
uniprot id: A8LN78
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

398580:DSHI RS05185
gene id: 398580:DSHI_RS05185
uniprot id: A8LSE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

398580:DSHI RS00055
gene id: 398580:DSHI_RS00055
uniprot id: A8LJT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

398580:DSHI RS13600
gene id: 398580:DSHI_RS13600
uniprot id: A8LIH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

398580:DSHI RS05695
gene id: 398580:DSHI_RS05695
uniprot id: A8LHQ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

398580:DSHI RS06620
gene id: 398580:DSHI_RS06620
uniprot id: A8LIS7
names: Similarity
messages: Belongs to the OmpW/AlkL family.

398580:DSHI RS14545
gene id: 398580:DSHI_RS14545
uniprot id: A8LJJ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

398580:DSHI RS17065
gene id: 398580:DSHI_RS17065
uniprot id: A8LNK7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

398580:DSHI RS13595
gene id: 398580:DSHI_RS13595
uniprot id: A8LIH1
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS15175
gene id: 398580:DSHI_RS15175
uniprot id: A8LKE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS11890
gene id: 398580:DSHI_RS11890
uniprot id: A8LRP2
names: Similarity
messages: Belongs to the cytochrome P450 family.

398580:DSHI RS15240
gene id: 398580:DSHI_RS15240
uniprot id: A8LKF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS09060
gene id: 398580:DSHI_RS09060
uniprot id: A8LMH6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

398580:DSHI RS09685
gene id: 398580:DSHI_RS09685
uniprot id: A8LNC9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

398580:DSHI RS05860
gene id: 398580:DSHI_RS05860
uniprot id: A8LHU2
names: Similarity
messages: Belongs to the peptidase M16 family.

398580:DSHI RS08400
gene id: 398580:DSHI_RS08400
uniprot id: A8LLL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS00330
gene id: 398580:DSHI_RS00330
uniprot id: A8LJZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS12225
gene id: 398580:DSHI_RS12225
uniprot id: A8LS44
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

398580:DSHI RS09185
gene id: 398580:DSHI_RS09185
uniprot id: A8LMJ9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

398580:DSHI RS05270
gene id: 398580:DSHI_RS05270
uniprot id: A8LSF7
names: Similarity
messages: Belongs to the TrpF family.

398580:DSHI RS10385
gene id: 398580:DSHI_RS10385
uniprot id: A8LPS3
names: Similarity
messages: Belongs to the UxaA family.

398580:DSHI RS19560
gene id: 398580:DSHI_RS19560
uniprot id: A8LT47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

398580:DSHI RS16760
gene id: 398580:DSHI_RS16760
uniprot id: A8LMW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

398580:DSHI RS05180
gene id: 398580:DSHI_RS05180
uniprot id: A8LSD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS15715
gene id: 398580:DSHI_RS15715
uniprot id: A8LL84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

398580:DSHI RS16885
gene id: 398580:DSHI_RS16885
uniprot id: A8LNH0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

398580:DSHI RS14555
gene id: 398580:DSHI_RS14555
uniprot id: A8LJJ8
names: PTM
messages: Binds 1 heme group per subunit.

398580:DSHI RS16465
gene id: 398580:DSHI_RS16465
uniprot id: A8LMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

398580:DSHI RS03665
gene id: 398580:DSHI_RS03665
uniprot id: A8LQH5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

398580:DSHI RS11215
gene id: 398580:DSHI_RS11215
uniprot id: A8LR19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

398580:DSHI RS17675
gene id: 398580:DSHI_RS17675
uniprot id: A8LPG0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

398580:DSHI RS01335
gene id: 398580:DSHI_RS01335
uniprot id: A8LM40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

398580:DSHI RS18440
gene id: 398580:DSHI_RS18440
uniprot id: A8LT11
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS20810
gene id: 398580:DSHI_RS20810
uniprot id: A8LUE0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

398580:DSHI RS05565
gene id: 398580:DSHI_RS05565
uniprot id: A8LHN3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

398580:DSHI RS19165
gene id: 398580:DSHI_RS19165
uniprot id: A8LTG1
names: Similarity
messages: Belongs to the CIA30 family.

398580:DSHI RS15210
gene id: 398580:DSHI_RS15210
uniprot id: A8LKE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

398580:DSHI RS02255
gene id: 398580:DSHI_RS02255
uniprot id: A8LN44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

398580:DSHI RS13095
gene id: 398580:DSHI_RS13095
uniprot id: A8LHX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

398580:DSHI RS13740
gene id: 398580:DSHI_RS13740
uniprot id: A8LIJ8
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS00540
gene id: 398580:DSHI_RS00540
uniprot id: A8LKL5
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS12155
gene id: 398580:DSHI_RS12155
uniprot id: A8LS30
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

398580:DSHI RS20505
gene id: 398580:DSHI_RS20505
uniprot id: A8LU82
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS16915
gene id: 398580:DSHI_RS16915
uniprot id: A8LNH6
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS15590
gene id: 398580:DSHI_RS15590
uniprot id: A8LL59
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

398580:DSHI RS13660
gene id: 398580:DSHI_RS13660
uniprot id: A8LII3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

398580:DSHI RS15935
gene id: 398580:DSHI_RS15935
uniprot id: A8LLW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS09170
gene id: 398580:DSHI_RS09170
uniprot id: A8LMJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

398580:DSHI RS14810
gene id: 398580:DSHI_RS14810
uniprot id: A8LJP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

398580:DSHI RS05910
gene id: 398580:DSHI_RS05910
uniprot id: A8LHV2
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

398580:DSHI RS09640
gene id: 398580:DSHI_RS09640
uniprot id: A8LNC0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS15390
gene id: 398580:DSHI_RS15390
uniprot id: A8LKI3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

398580:DSHI RS04065
gene id: 398580:DSHI_RS04065
uniprot id: A8LQZ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

398580:DSHI RS06725
gene id: 398580:DSHI_RS06725
uniprot id: A8LIU8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS16780
gene id: 398580:DSHI_RS16780
uniprot id: A8LNF0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

398580:DSHI RS18030
gene id: 398580:DSHI_RS18030
uniprot id: A8LQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

398580:DSHI RS00975
gene id: 398580:DSHI_RS00975
uniprot id: A8LLD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

398580:DSHI RS12355
gene id: 398580:DSHI_RS12355
uniprot id: A8LS69
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

398580:DSHI RS17550
gene id: 398580:DSHI_RS17550
uniprot id: A8LPD5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

398580:DSHI RS00865
gene id: 398580:DSHI_RS00865
uniprot id: A8LLB3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

398580:DSHI RS16580
gene id: 398580:DSHI_RS16580
uniprot id: A8LMS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

398580:DSHI RS14765
gene id: 398580:DSHI_RS14765
uniprot id: A8LJP0
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS02845
gene id: 398580:DSHI_RS02845
uniprot id: A8LPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

398580:DSHI RS10180
gene id: 398580:DSHI_RS10180
uniprot id: A8LP54
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

398580:DSHI RS17295
gene id: 398580:DSHI_RS17295
uniprot id: A8LP83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

398580:DSHI RS11505
gene id: 398580:DSHI_RS11505
uniprot id: A8LR77
names: Similarity
messages: Belongs to the GcvT family.

398580:DSHI RS16815
gene id: 398580:DSHI_RS16815
uniprot id: A8LNF7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

398580:DSHI RS19765
gene id: 398580:DSHI_RS19765
uniprot id: A8LTT3
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS05520
gene id: 398580:DSHI_RS05520
uniprot id: A8LSK7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

398580:DSHI RS15700
gene id: 398580:DSHI_RS15700
uniprot id: A8LL81
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

398580:DSHI RS06610
gene id: 398580:DSHI_RS06610
uniprot id: A8LIS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS15605
gene id: 398580:DSHI_RS15605
uniprot id: A8LL62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

398580:DSHI RS14425
gene id: 398580:DSHI_RS14425
uniprot id: A8LJ80
names: Similarity
messages: Belongs to the BMP lipoprotein family.

398580:DSHI RS15275
gene id: 398580:DSHI_RS15275
uniprot id: A8LKG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

398580:DSHI RS14645
gene id: 398580:DSHI_RS14645
uniprot id: A8LJL6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

398580:DSHI RS16230
gene id: 398580:DSHI_RS16230
uniprot id: A8LM26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

398580:DSHI RS07615
gene id: 398580:DSHI_RS07615
uniprot id: A8LK38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

398580:DSHI RS01560
gene id: 398580:DSHI_RS01560
uniprot id: A8LM85
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

398580:DSHI RS00510
gene id: 398580:DSHI_RS00510
uniprot id: A8LKK9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

398580:DSHI RS10940
gene id: 398580:DSHI_RS10940
uniprot id: A8LQL9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

398580:DSHI RS05955
gene id: 398580:DSHI_RS05955
uniprot id: A8LHW1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

398580:DSHI RS20890
gene id: 398580:DSHI_RS20890
uniprot id: A8LUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS07465
gene id: 398580:DSHI_RS07465
uniprot id: A8LK09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS09970
gene id: 398580:DSHI_RS09970
uniprot id: A8LP15
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

398580:DSHI RS08265
gene id: 398580:DSHI_RS08265
uniprot id: A8LL02
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS15370
gene id: 398580:DSHI_RS15370
uniprot id: A8LKH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has four main subunits: a(1), b(1), b'(1) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta, b and b' chains.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

398580:DSHI RS17840
gene id: 398580:DSHI_RS17840
uniprot id: A8LQ18
names: Function
names: PTM
messages: Binds 4 heme groups per subunit.
messages: The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.

398580:DSHI RS06070
gene id: 398580:DSHI_RS06070
uniprot id: A8LI77
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS14140
gene id: 398580:DSHI_RS14140
uniprot id: A8LJ23
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

398580:DSHI RS18600
gene id: 398580:DSHI_RS18600
uniprot id: A8LT47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

398580:DSHI RS21165
gene id: 398580:DSHI_RS21165
uniprot id: A8LUL1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

398580:DSHI RS05260
gene id: 398580:DSHI_RS05260
uniprot id: A8LSF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

398580:DSHI RS12560
gene id: 398580:DSHI_RS12560
uniprot id: A8LSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

398580:DSHI RS19260
gene id: 398580:DSHI_RS19260
uniprot id: A8LTI0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

398580:DSHI RS08825
gene id: 398580:DSHI_RS08825
uniprot id: A8LLU7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

398580:DSHI RS16500
gene id: 398580:DSHI_RS16500
uniprot id: A8LMR4
names: Similarity
messages: Belongs to the type III secretion exporter family.

398580:DSHI RS04080
gene id: 398580:DSHI_RS04080
uniprot id: A8LR00
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

398580:DSHI RS03570
gene id: 398580:DSHI_RS03570
uniprot id: A8LQF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS13695
gene id: 398580:DSHI_RS13695
uniprot id: A8LII9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS10585
gene id: 398580:DSHI_RS10585
uniprot id: A8LPW3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

398580:DSHI RS14675
gene id: 398580:DSHI_RS14675
uniprot id: A8LJM2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

398580:DSHI RS01580
gene id: 398580:DSHI_RS01580
uniprot id: A8LM89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

398580:DSHI RS07620
gene id: 398580:DSHI_RS07620
uniprot id: A8LK39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

398580:DSHI RS04890
gene id: 398580:DSHI_RS04890
uniprot id: A8LRZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS03670
gene id: 398580:DSHI_RS03670
uniprot id: A8LQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

398580:DSHI RS04405
gene id: 398580:DSHI_RS04405
uniprot id: A8LRF5
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS15470
gene id: 398580:DSHI_RS15470
uniprot id: A8LL33
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

398580:DSHI RS09360
gene id: 398580:DSHI_RS09360
uniprot id: A8LN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS12635
gene id: 398580:DSHI_RS12635
uniprot id: A8LSM0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

398580:DSHI RS07365
gene id: 398580:DSHI_RS07365
uniprot id: A8LJG6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS07650
gene id: 398580:DSHI_RS07650
uniprot id: A8LK45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

398580:DSHI RS16360
gene id: 398580:DSHI_RS16360
uniprot id: A8LMN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS15995
gene id: 398580:DSHI_RS15995
uniprot id: A8LLX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS10175
gene id: 398580:DSHI_RS10175
uniprot id: A8LP53
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

398580:DSHI RS15110
gene id: 398580:DSHI_RS15110
uniprot id: A8LKC9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

398580:DSHI RS05200
gene id: 398580:DSHI_RS05200
uniprot id: A8LSE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

398580:DSHI RS06535
gene id: 398580:DSHI_RS06535
uniprot id: A8LIR0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

398580:DSHI RS06975
gene id: 398580:DSHI_RS06975
uniprot id: A8LJ90
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

398580:DSHI RS18060
gene id: 398580:DSHI_RS18060
uniprot id: A8LQ62
names: Similarity
messages: Belongs to the UPF0758 family.

398580:DSHI RS11090
gene id: 398580:DSHI_RS11090
uniprot id: A8LQP8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

398580:DSHI RS08070
gene id: 398580:DSHI_RS08070
uniprot id: A8LKW4
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

398580:DSHI RS01645
gene id: 398580:DSHI_RS01645
uniprot id: A8LMA2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

398580:DSHI RS08960
gene id: 398580:DSHI_RS08960
uniprot id: A8LMF7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

398580:DSHI RS18325
gene id: 398580:DSHI_RS18325
uniprot id: A8LSY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

398580:DSHI RS12070
gene id: 398580:DSHI_RS12070
uniprot id: A8LRS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

398580:DSHI RS01680
gene id: 398580:DSHI_RS01680
uniprot id: A8LMA7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

398580:DSHI RS12305
gene id: 398580:DSHI_RS12305
uniprot id: A8LS59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

398580:DSHI RS10190
gene id: 398580:DSHI_RS10190
uniprot id: A8LP56
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS11775
gene id: 398580:DSHI_RS11775
uniprot id: A8LRM0
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

398580:DSHI RS14445
gene id: 398580:DSHI_RS14445
uniprot id: A8LJ84
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS03410
gene id: 398580:DSHI_RS03410
uniprot id: A8LQC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

398580:DSHI RS00795
gene id: 398580:DSHI_RS00795
uniprot id: A8LKR6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

398580:DSHI RS03970
gene id: 398580:DSHI_RS03970
uniprot id: A8LQX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS03225
gene id: 398580:DSHI_RS03225
uniprot id: A8LQ90
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

398580:DSHI RS06985
gene id: 398580:DSHI_RS06985
uniprot id: A8LJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS04715
gene id: 398580:DSHI_RS04715
uniprot id: A8LRW0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

398580:DSHI RS19905
gene id: 398580:DSHI_RS19905
uniprot id: A8LSY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

398580:DSHI RS17625
gene id: 398580:DSHI_RS17625
uniprot id: A8LPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

398580:DSHI RS17115
gene id: 398580:DSHI_RS17115
uniprot id: A8LNL8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

398580:DSHI RS13950
gene id: 398580:DSHI_RS13950
uniprot id: A8LIP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS15425
gene id: 398580:DSHI_RS15425
uniprot id: A8LL24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

398580:DSHI RS13275
gene id: 398580:DSHI_RS13275
uniprot id: A8LI14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS18040
gene id: 398580:DSHI_RS18040
uniprot id: A8LQ58
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

398580:DSHI RS15395
gene id: 398580:DSHI_RS15395
uniprot id: A8LKI4
names: Similarity
messages: Belongs to the SDHAF4 family.

398580:DSHI RS19925
gene id: 398580:DSHI_RS19925
uniprot id: A8LSY4
names: Similarity
messages: Belongs to the SCO1/2 family.

398580:DSHI RS08055
gene id: 398580:DSHI_RS08055
uniprot id: A8LKW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

398580:DSHI RS01730
gene id: 398580:DSHI_RS01730
uniprot id: A8LMB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

398580:DSHI RS01770
gene id: 398580:DSHI_RS01770
uniprot id: A8LMC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

398580:DSHI RS12295
gene id: 398580:DSHI_RS12295
uniprot id: A8LS57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

398580:DSHI RS17005
gene id: 398580:DSHI_RS17005
uniprot id: A8LNJ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

398580:DSHI RS09215
gene id: 398580:DSHI_RS09215
uniprot id: A8LMK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS21415
gene id: 398580:DSHI_RS21415
uniprot id: A8LS93
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

398580:DSHI RS17110
gene id: 398580:DSHI_RS17110
uniprot id: A8LNL7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

398580:DSHI RS04525
gene id: 398580:DSHI_RS04525
uniprot id: A8LRI0
names: Subcellular Location Annotation
messages: Cell inner membrane

398580:DSHI RS11250
gene id: 398580:DSHI_RS11250
uniprot id: A8LR26
names: Similarity
messages: Belongs to the universal stress protein A family.

398580:DSHI RS02765
gene id: 398580:DSHI_RS02765
uniprot id: A8LPG9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS00135
gene id: 398580:DSHI_RS00135
uniprot id: A8LJV1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

398580:DSHI RS05515
gene id: 398580:DSHI_RS05515
uniprot id: A8LSK6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

398580:DSHI RS14580
gene id: 398580:DSHI_RS14580
uniprot id: A8LJK4
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

398580:DSHI RS07715
gene id: 398580:DSHI_RS07715
uniprot id: A8LK58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS06575
gene id: 398580:DSHI_RS06575
uniprot id: A8LIR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

398580:DSHI RS20110
gene id: 398580:DSHI_RS20110
uniprot id: A8LU14
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

398580:DSHI RS14715
gene id: 398580:DSHI_RS14715
uniprot id: A8LJN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components.

398580:DSHI RS10490
gene id: 398580:DSHI_RS10490
uniprot id: A8LPU4
names: Similarity
messages: Belongs to the aspartokinase family.

398580:DSHI RS05395
gene id: 398580:DSHI_RS05395
uniprot id: A8LSI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS08340
gene id: 398580:DSHI_RS08340
uniprot id: A8LL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS14160
gene id: 398580:DSHI_RS14160
uniprot id: A8LJ27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

398580:DSHI RS17820
gene id: 398580:DSHI_RS17820
uniprot id: A8LQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components.

398580:DSHI RS09025
gene id: 398580:DSHI_RS09025
uniprot id: A8LMH0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

398580:DSHI RS14145
gene id: 398580:DSHI_RS14145
uniprot id: A8LJ24
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

398580:DSHI RS05850
gene id: 398580:DSHI_RS05850
uniprot id: A8LHU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS07165
gene id: 398580:DSHI_RS07165
uniprot id: A8LJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

398580:DSHI RS07470
gene id: 398580:DSHI_RS07470
uniprot id: A8LK10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

398580:DSHI RS17350
gene id: 398580:DSHI_RS17350
uniprot id: A8LP94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

398580:DSHI RS08905
gene id: 398580:DSHI_RS08905
uniprot id: A8LME6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

398580:DSHI RS04970
gene id: 398580:DSHI_RS04970
uniprot id: A8LS09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS13330
gene id: 398580:DSHI_RS13330
uniprot id: A8LI25
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS09140
gene id: 398580:DSHI_RS09140
uniprot id: A8LMJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

398580:DSHI RS04505
gene id: 398580:DSHI_RS04505
uniprot id: A8LRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

398580:DSHI RS17670
gene id: 398580:DSHI_RS17670
uniprot id: A8LPF9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS00720
gene id: 398580:DSHI_RS00720
uniprot id: A8LKQ1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

398580:DSHI RS11180
gene id: 398580:DSHI_RS11180
uniprot id: A8LQR8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

398580:DSHI RS06170
gene id: 398580:DSHI_RS06170
uniprot id: A8LI96
names: Similarity
messages: Belongs to the virb1 family.

398580:DSHI RS05755
gene id: 398580:DSHI_RS05755
uniprot id: A8LHS1
names: Similarity
messages: Belongs to the GSP E family.

398580:DSHI RS21955
gene id: 398580:DSHI_RS21955
uniprot id: A8LTF1
names: Subcellular Location Annotation
messages: Cell membrane

398580:DSHI RS07575
gene id: 398580:DSHI_RS07575
uniprot id: A8LK30
names: Subcellular Location Annotation
messages: Cell inner membrane

398580:DSHI RS03025
gene id: 398580:DSHI_RS03025
uniprot id: A8LPL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

398580:DSHI RS08420
gene id: 398580:DSHI_RS08420
uniprot id: A8LLL8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

398580:DSHI RS00900
gene id: 398580:DSHI_RS00900
uniprot id: A8LLC0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

398580:DSHI RS17855
gene id: 398580:DSHI_RS17855
uniprot id: A8LQ21
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. ChlP subfamily.

398580:DSHI RS10080
gene id: 398580:DSHI_RS10080
uniprot id: A8LP35
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS03285
gene id: 398580:DSHI_RS03285
uniprot id: A8LQA2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS06895
gene id: 398580:DSHI_RS06895
uniprot id: A8LIY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS06940
gene id: 398580:DSHI_RS06940
uniprot id: A8LIZ1
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

398580:DSHI RS15520
gene id: 398580:DSHI_RS15520
uniprot id: A8LL43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

398580:DSHI RS00745
gene id: 398580:DSHI_RS00745
uniprot id: A8LKQ6
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

398580:DSHI RS16010
gene id: 398580:DSHI_RS16010
uniprot id: A8LLY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS03495
gene id: 398580:DSHI_RS03495
uniprot id: A8LQE3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

398580:DSHI RS13935
gene id: 398580:DSHI_RS13935
uniprot id: A8LIN7
names: Similarity
messages: Belongs to the PhzF family.

398580:DSHI RS13295
gene id: 398580:DSHI_RS13295
uniprot id: A8LI18
names: Similarity
messages: Belongs to the CutA family.

398580:DSHI RS17540
gene id: 398580:DSHI_RS17540
uniprot id: A8LPD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

398580:DSHI RS12545
gene id: 398580:DSHI_RS12545
uniprot id: A8LSA7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

398580:DSHI RS10955
gene id: 398580:DSHI_RS10955
uniprot id: A8LQM2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

398580:DSHI RS06765
gene id: 398580:DSHI_RS06765
uniprot id: A8LIV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS09300
gene id: 398580:DSHI_RS09300
uniprot id: A8LML9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS05130
gene id: 398580:DSHI_RS05130
uniprot id: A8LSC9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

398580:DSHI RS03720
gene id: 398580:DSHI_RS03720
uniprot id: A8LQS9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS07005
gene id: 398580:DSHI_RS07005
uniprot id: A8LJ96
names: Similarity
messages: Belongs to the creatininase superfamily.

398580:DSHI RS15925
gene id: 398580:DSHI_RS15925
uniprot id: A8LLW5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS17685
gene id: 398580:DSHI_RS17685
uniprot id: A8LPG2
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS04255
gene id: 398580:DSHI_RS04255
uniprot id: A8LRC6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

398580:DSHI RS03870
gene id: 398580:DSHI_RS03870
uniprot id: A8LQV9
names: Similarity
messages: Belongs to the selenium-binding protein family.

398580:DSHI RS12835
gene id: 398580:DSHI_RS12835
uniprot id: A8LSQ8
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS15260
gene id: 398580:DSHI_RS15260
uniprot id: A8LKF7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

398580:DSHI RS01250
gene id: 398580:DSHI_RS01250
uniprot id: A8LLJ0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

398580:DSHI RS08570
gene id: 398580:DSHI_RS08570
uniprot id: A8LLP7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

398580:DSHI RS03815
gene id: 398580:DSHI_RS03815
uniprot id: A8LQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

398580:DSHI RS01535
gene id: 398580:DSHI_RS01535
uniprot id: A8LM80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

398580:DSHI RS01230
gene id: 398580:DSHI_RS01230
uniprot id: A8LLI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

398580:DSHI RS01420
gene id: 398580:DSHI_RS01420
uniprot id: A8LM57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

398580:DSHI RS09125
gene id: 398580:DSHI_RS09125
uniprot id: A8LMI7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

398580:DSHI RS14685
gene id: 398580:DSHI_RS14685
uniprot id: A8LJM4
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

398580:DSHI RS15730
gene id: 398580:DSHI_RS15730
uniprot id: A8LL87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

398580:DSHI RS08955
gene id: 398580:DSHI_RS08955
uniprot id: A8LMF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

398580:DSHI RS07545
gene id: 398580:DSHI_RS07545
uniprot id: A8LK25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS06125
gene id: 398580:DSHI_RS06125
uniprot id: A8LI88
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS18260
gene id: 398580:DSHI_RS18260
uniprot id: A8LSX3
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS07525
gene id: 398580:DSHI_RS07525
uniprot id: A8LK21
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS18235
gene id: 398580:DSHI_RS18235
uniprot id: A8LSW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

398580:DSHI RS20685
gene id: 398580:DSHI_RS20685
uniprot id: A8LUB9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

398580:DSHI RS01500
gene id: 398580:DSHI_RS01500
uniprot id: A8LM73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

398580:DSHI RS14020
gene id: 398580:DSHI_RS14020
uniprot id: A8LIZ9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS09050
gene id: 398580:DSHI_RS09050
uniprot id: A8LMH4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

398580:DSHI RS09090
gene id: 398580:DSHI_RS09090
uniprot id: A8LMI1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

398580:DSHI RS01795
gene id: 398580:DSHI_RS01795
uniprot id: A8LMD0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

398580:DSHI RS10665
gene id: 398580:DSHI_RS10665
uniprot id: A8LPX9
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

398580:DSHI RS19725
gene id: 398580:DSHI_RS19725
uniprot id: A8LTS3
names: Similarity
messages: Belongs to the Dps family.

398580:DSHI RS19480
gene id: 398580:DSHI_RS19480
uniprot id: A8LTM2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

398580:DSHI RS09485
gene id: 398580:DSHI_RS09485
uniprot id: A8LN88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

398580:DSHI RS19610
gene id: 398580:DSHI_RS19610
uniprot id: A8LTQ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

398580:DSHI RS05095
gene id: 398580:DSHI_RS05095
uniprot id: A8LSC2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

398580:DSHI RS12060
gene id: 398580:DSHI_RS12060
uniprot id: A8LRS4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

398580:DSHI RS07880
gene id: 398580:DSHI_RS07880
uniprot id: A8LK91
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

398580:DSHI RS08640
gene id: 398580:DSHI_RS08640
uniprot id: A8LLR2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS02980
gene id: 398580:DSHI_RS02980
uniprot id: A8LPK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS07885
gene id: 398580:DSHI_RS07885
uniprot id: A8LK92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

398580:DSHI RS14990
gene id: 398580:DSHI_RS14990
uniprot id: A8LKA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS15360
gene id: 398580:DSHI_RS15360
uniprot id: A8LKH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

398580:DSHI RS12645
gene id: 398580:DSHI_RS12645
uniprot id: A8LSM2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

398580:DSHI RS07135
gene id: 398580:DSHI_RS07135
uniprot id: A8LJC2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS03860
gene id: 398580:DSHI_RS03860
uniprot id: A8LQV7
names: Function
messages: Multidrug efflux pump.

398580:DSHI RS02420
gene id: 398580:DSHI_RS02420
uniprot id: A8LNR3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

398580:DSHI RS11150
gene id: 398580:DSHI_RS11150
uniprot id: A8LQR0
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

398580:DSHI RS00810
gene id: 398580:DSHI_RS00810
uniprot id: A8LKR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

398580:DSHI RS11130
gene id: 398580:DSHI_RS11130
uniprot id: A8LQQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

398580:DSHI RS16240
gene id: 398580:DSHI_RS16240
uniprot id: A8LM28
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

398580:DSHI RS00550
gene id: 398580:DSHI_RS00550
uniprot id: A8LKL7
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS12370
gene id: 398580:DSHI_RS12370
uniprot id: A8LS72
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS12105
gene id: 398580:DSHI_RS12105
uniprot id: A8LRT3
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

398580:DSHI RS01220
gene id: 398580:DSHI_RS01220
uniprot id: A8LLI3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

398580:DSHI RS08280
gene id: 398580:DSHI_RS08280
uniprot id: A8LL05
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

398580:DSHI RS03565
gene id: 398580:DSHI_RS03565
uniprot id: A8LQF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS06500
gene id: 398580:DSHI_RS06500
uniprot id: A8LIQ3
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS15930
gene id: 398580:DSHI_RS15930
uniprot id: A8LLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS19205
gene id: 398580:DSHI_RS19205
uniprot id: A8LTG9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS13165
gene id: 398580:DSHI_RS13165
uniprot id: A8LHZ1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

398580:DSHI RS10620
gene id: 398580:DSHI_RS10620
uniprot id: A8LPX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

398580:DSHI RS05745
gene id: 398580:DSHI_RS05745
uniprot id: A8LHR9
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS09670
gene id: 398580:DSHI_RS09670
uniprot id: A8LNC6
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

398580:DSHI RS13090
gene id: 398580:DSHI_RS13090
uniprot id: A8LSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

398580:DSHI RS21010
gene id: 398580:DSHI_RS21010
uniprot id: A8LUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS10415
gene id: 398580:DSHI_RS10415
uniprot id: A8LPS9
names: Similarity
messages: Belongs to the TPP enzyme family.

398580:DSHI RS00445
gene id: 398580:DSHI_RS00445
uniprot id: A8LKJ7
names: Similarity
messages: Belongs to the peptidase S41A family.

398580:DSHI RS15635
gene id: 398580:DSHI_RS15635
uniprot id: A8LL68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

398580:DSHI RS04510
gene id: 398580:DSHI_RS04510
uniprot id: A8LRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

398580:DSHI RS12445
gene id: 398580:DSHI_RS12445
uniprot id: A8LS87
names: Similarity
messages: Belongs to the DapA family.

398580:DSHI RS04545
gene id: 398580:DSHI_RS04545
uniprot id: A8LRI4
names: Similarity
messages: Belongs to the DSD1 family.

398580:DSHI RS06300
gene id: 398580:DSHI_RS06300
uniprot id: A8LIC3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

398580:DSHI RS14450
gene id: 398580:DSHI_RS14450
uniprot id: A8LJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS05700
gene id: 398580:DSHI_RS05700
uniprot id: A8LHR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

398580:DSHI RS08385
gene id: 398580:DSHI_RS08385
uniprot id: A8LLL1
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

398580:DSHI RS19340
gene id: 398580:DSHI_RS19340
uniprot id: A8LTJ6
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

398580:DSHI RS17825
gene id: 398580:DSHI_RS17825
uniprot id: A8LQ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex alpha subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components.

398580:DSHI RS01385
gene id: 398580:DSHI_RS01385
uniprot id: A8LM50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

398580:DSHI RS00960
gene id: 398580:DSHI_RS00960
uniprot id: A8LLD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

398580:DSHI RS09070
gene id: 398580:DSHI_RS09070
uniprot id: A8LMH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

398580:DSHI RS15575
gene id: 398580:DSHI_RS15575
uniprot id: A8LL56
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

398580:DSHI RS11750
gene id: 398580:DSHI_RS11750
uniprot id: A8LRL6
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

398580:DSHI RS00695
gene id: 398580:DSHI_RS00695
uniprot id: A8LKP6
names: Similarity
messages: Belongs to the MlaA family.

398580:DSHI RS00905
gene id: 398580:DSHI_RS00905
uniprot id: A8LLC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

398580:DSHI RS09505
gene id: 398580:DSHI_RS09505
uniprot id: A8LN92
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS12315
gene id: 398580:DSHI_RS12315
uniprot id: A8LS61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

398580:DSHI RS18450
gene id: 398580:DSHI_RS18450
uniprot id: A8LT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

398580:DSHI RS00640
gene id: 398580:DSHI_RS00640
uniprot id: A8LKN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

398580:DSHI RS00730
gene id: 398580:DSHI_RS00730
uniprot id: A8LKQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

398580:DSHI RS04060
gene id: 398580:DSHI_RS04060
uniprot id: A8LQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

398580:DSHI RS05100
gene id: 398580:DSHI_RS05100
uniprot id: A8LSC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS02885
gene id: 398580:DSHI_RS02885
uniprot id: A8LPJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

398580:DSHI RS09325
gene id: 398580:DSHI_RS09325
uniprot id: A8LN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

398580:DSHI RS15045
gene id: 398580:DSHI_RS15045
uniprot id: A8LKB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

398580:DSHI RS08245
gene id: 398580:DSHI_RS08245
uniprot id: A8LKZ9
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

398580:DSHI RS09265
gene id: 398580:DSHI_RS09265
uniprot id: A8LML3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

398580:DSHI RS11935
gene id: 398580:DSHI_RS11935
uniprot id: A8LRQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

398580:DSHI RS04210
gene id: 398580:DSHI_RS04210
uniprot id: A8LRB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS10475
gene id: 398580:DSHI_RS10475
uniprot id: A8LPU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

398580:DSHI RS17850
gene id: 398580:DSHI_RS17850
uniprot id: A8LQ20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

398580:DSHI RS16520
gene id: 398580:DSHI_RS16520
uniprot id: A8LMR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

398580:DSHI RS13985
gene id: 398580:DSHI_RS13985
uniprot id: A8LIP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS07770
gene id: 398580:DSHI_RS07770
uniprot id: A8LK69
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

398580:DSHI RS07480
gene id: 398580:DSHI_RS07480
uniprot id: A8LK12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

398580:DSHI RS12065
gene id: 398580:DSHI_RS12065
uniprot id: A8LRS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

398580:DSHI RS04765
gene id: 398580:DSHI_RS04765
uniprot id: A8LRW9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

398580:DSHI RS14155
gene id: 398580:DSHI_RS14155
uniprot id: A8LJ26
names: Similarity
messages: Belongs to the UPF0173 family.

398580:DSHI RS09210
gene id: 398580:DSHI_RS09210
uniprot id: A8LMK4
names: Similarity
messages: Belongs to the universal stress protein A family.

398580:DSHI RS10995
gene id: 398580:DSHI_RS10995
uniprot id: A8LQN0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

398580:DSHI RS03575
gene id: 398580:DSHI_RS03575
uniprot id: A8LQF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS13290
gene id: 398580:DSHI_RS13290
uniprot id: A8LI17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

398580:DSHI RS03450
gene id: 398580:DSHI_RS03450
uniprot id: A8LQD4
names: Subunit
messages: Homodimer.

398580:DSHI RS05460
gene id: 398580:DSHI_RS05460
uniprot id: A8LSJ5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

398580:DSHI RS01020
gene id: 398580:DSHI_RS01020
uniprot id: A8LLE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS13835
gene id: 398580:DSHI_RS13835
uniprot id: A8LIL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

398580:DSHI RS15410
gene id: 398580:DSHI_RS15410
uniprot id: A8LL21
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

398580:DSHI RS19980
gene id: 398580:DSHI_RS19980
uniprot id: A8LTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS01665
gene id: 398580:DSHI_RS01665
uniprot id: A8LMA5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

398580:DSHI RS09000
gene id: 398580:DSHI_RS09000
uniprot id: A8LMG4
names: Similarity
messages: Belongs to the LOG family.

398580:DSHI RS02740
gene id: 398580:DSHI_RS02740
uniprot id: A8LNX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

398580:DSHI RS07095
gene id: 398580:DSHI_RS07095
uniprot id: A8LJB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

398580:DSHI RS01065
gene id: 398580:DSHI_RS01065
uniprot id: A8LLF3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

398580:DSHI RS06045
gene id: 398580:DSHI_RS06045
uniprot id: A8LI72
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

398580:DSHI RS20540
gene id: 398580:DSHI_RS20540
uniprot id: A8LU89
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

398580:DSHI RS08150
gene id: 398580:DSHI_RS08150
uniprot id: A8LKY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

398580:DSHI RS15445
gene id: 398580:DSHI_RS15445
uniprot id: A8LL28
names: Similarity
messages: Belongs to the tannase family.

398580:DSHI RS01075
gene id: 398580:DSHI_RS01075
uniprot id: A8LLF5
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

398580:DSHI RS05505
gene id: 398580:DSHI_RS05505
uniprot id: A8LSK4
names: Similarity
messages: Belongs to the SAICAR synthetase family.

398580:DSHI RS19860
gene id: 398580:DSHI_RS19860
uniprot id: A8LSX0
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS16555
gene id: 398580:DSHI_RS16555
uniprot id: A8LMS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

398580:DSHI RS06900
gene id: 398580:DSHI_RS06900
uniprot id: A8LIY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS15310
gene id: 398580:DSHI_RS15310
uniprot id: A8LKG7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

398580:DSHI RS04030
gene id: 398580:DSHI_RS04030
uniprot id: A8LQZ0
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

398580:DSHI RS12720
gene id: 398580:DSHI_RS12720
uniprot id: A8LSN5
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS06755
gene id: 398580:DSHI_RS06755
uniprot id: A8LIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS13650
gene id: 398580:DSHI_RS13650
uniprot id: A8LII1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

398580:DSHI RS02435
gene id: 398580:DSHI_RS02435
uniprot id: A8LNR6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

398580:DSHI RS17275
gene id: 398580:DSHI_RS17275
uniprot id: A8LP79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS00415
gene id: 398580:DSHI_RS00415
uniprot id: A8LKJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

398580:DSHI RS16445
gene id: 398580:DSHI_RS16445
uniprot id: A8LMQ4
names: Subcellular Location Annotation
messages: Cytoplasm

398580:DSHI RS20065
gene id: 398580:DSHI_RS20065
uniprot id: A8LU05
names: Similarity
messages: Belongs to the TrbL/VirB6 family.

398580:DSHI RS04845
gene id: 398580:DSHI_RS04845
uniprot id: A8LRY6
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

398580:DSHI RS16895
gene id: 398580:DSHI_RS16895
uniprot id: A8LNH2
names: Similarity
messages: Belongs to the UPF0246 family.

398580:DSHI RS16245
gene id: 398580:DSHI_RS16245
uniprot id: A8LM29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

398580:DSHI RS17770
gene id: 398580:DSHI_RS17770
uniprot id: A8LQ04
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS04350
gene id: 398580:DSHI_RS04350
uniprot id: A8LRE5
names: Similarity
messages: Belongs to the DEAD box helicase family.

398580:DSHI RS12670
gene id: 398580:DSHI_RS12670
uniprot id: A8LSM6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

398580:DSHI RS05010
gene id: 398580:DSHI_RS05010
uniprot id: A8LS15
names: Similarity
messages: Belongs to the UPF0262 family.

398580:DSHI RS17205
gene id: 398580:DSHI_RS17205
uniprot id: A8LNN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

398580:DSHI RS18525
gene id: 398580:DSHI_RS18525
uniprot id: A8LT29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

398580:DSHI RS15560
gene id: 398580:DSHI_RS15560
uniprot id: A8LL52
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS14395
gene id: 398580:DSHI_RS14395
uniprot id: A8LJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS18080
gene id: 398580:DSHI_RS18080
uniprot id: A8LQ66
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS12265
gene id: 398580:DSHI_RS12265
uniprot id: A8LS51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

398580:DSHI RS00710
gene id: 398580:DSHI_RS00710
uniprot id: A8LKP9
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

398580:DSHI RS03470
gene id: 398580:DSHI_RS03470
uniprot id: A8LQD8
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS00820
gene id: 398580:DSHI_RS00820
uniprot id: A8LKS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

398580:DSHI RS03455
gene id: 398580:DSHI_RS03455
uniprot id: A8LQD5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

398580:DSHI RS07120
gene id: 398580:DSHI_RS07120
uniprot id: A8LJB9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS15025
gene id: 398580:DSHI_RS15025
uniprot id: A8LKB2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS02965
gene id: 398580:DSHI_RS02965
uniprot id: A8LPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

398580:DSHI RS21105
gene id: 398580:DSHI_RS21105
uniprot id: A8LUJ9
names: Function
messages: Acts on leucine, isoleucine and valine.

398580:DSHI RS01525
gene id: 398580:DSHI_RS01525
uniprot id: A8LM78
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

398580:DSHI RS01380
gene id: 398580:DSHI_RS01380
uniprot id: A8LM49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

398580:DSHI RS01475
gene id: 398580:DSHI_RS01475
uniprot id: A8LM68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

398580:DSHI RS15380
gene id: 398580:DSHI_RS15380
uniprot id: A8LKI1
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

398580:DSHI RS14070
gene id: 398580:DSHI_RS14070
uniprot id: A8LJ09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

398580:DSHI RS14755
gene id: 398580:DSHI_RS14755
uniprot id: A8LJN8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

398580:DSHI RS08835
gene id: 398580:DSHI_RS08835
uniprot id: A8LLU9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

398580:DSHI RS10805
gene id: 398580:DSHI_RS10805
uniprot id: A8LQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS04645
gene id: 398580:DSHI_RS04645
uniprot id: A8LRU6
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

398580:DSHI RS16045
gene id: 398580:DSHI_RS16045
uniprot id: A8LLY9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

398580:DSHI RS04410
gene id: 398580:DSHI_RS04410
uniprot id: A8LRF6
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS02635
gene id: 398580:DSHI_RS02635
uniprot id: A8LNV8
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

398580:DSHI RS05940
gene id: 398580:DSHI_RS05940
uniprot id: A8LHV8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

398580:DSHI RS21030
gene id: 398580:DSHI_RS21030
uniprot id: A8LUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS05815
gene id: 398580:DSHI_RS05815
uniprot id: A8LHT3
names: Similarity
messages: Belongs to the DprA/Smf family.

398580:DSHI RS15300
gene id: 398580:DSHI_RS15300
uniprot id: A8LKG5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS17510
gene id: 398580:DSHI_RS17510
uniprot id: A8LPC6
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

398580:DSHI RS05730
gene id: 398580:DSHI_RS05730
uniprot id: A8LHR6
names: Similarity
messages: Belongs to the peptidase A24 family.

398580:DSHI RS05690
gene id: 398580:DSHI_RS05690
uniprot id: A8LHQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

398580:DSHI RS00030
gene id: 398580:DSHI_RS00030
uniprot id: A8LJS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

398580:DSHI RS07625
gene id: 398580:DSHI_RS07625
uniprot id: A8LK40
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS18630
gene id: 398580:DSHI_RS18630
uniprot id: A8LT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

398580:DSHI RS06355
gene id: 398580:DSHI_RS06355
uniprot id: A8LID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS01040
gene id: 398580:DSHI_RS01040
uniprot id: A8LLE8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

398580:DSHI RS17135
gene id: 398580:DSHI_RS17135
uniprot id: A8LNM2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS03270
gene id: 398580:DSHI_RS03270
uniprot id: A8LQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS15950
gene id: 398580:DSHI_RS15950
uniprot id: A8LLX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

398580:DSHI RS06090
gene id: 398580:DSHI_RS06090
uniprot id: A8LI81
names: Similarity
messages: Belongs to the cytochrome P450 family.

398580:DSHI RS18020
gene id: 398580:DSHI_RS18020
uniprot id: A8LQ54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

398580:DSHI RS01325
gene id: 398580:DSHI_RS01325
uniprot id: A8LLK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

398580:DSHI RS17860
gene id: 398580:DSHI_RS17860
uniprot id: A8LQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

398580:DSHI RS11395
gene id: 398580:DSHI_RS11395
uniprot id: A8LR55
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

398580:DSHI RS12290
gene id: 398580:DSHI_RS12290
uniprot id: A8LS56
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

398580:DSHI RS05600
gene id: 398580:DSHI_RS05600
uniprot id: A8LHP0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

398580:DSHI RS01195
gene id: 398580:DSHI_RS01195
uniprot id: A8LLH8
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

398580:DSHI RS11785
gene id: 398580:DSHI_RS11785
uniprot id: A8LRM2
names: Similarity
messages: Belongs to the CFA/CMAS family.

398580:DSHI RS13190
gene id: 398580:DSHI_RS13190
uniprot id: A8LHZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

398580:DSHI RS06025
gene id: 398580:DSHI_RS06025
uniprot id: A8LI68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

398580:DSHI RS10990
gene id: 398580:DSHI_RS10990
uniprot id: A8LQM9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

398580:DSHI RS12330
gene id: 398580:DSHI_RS12330
uniprot id: A8LS64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS09835
gene id: 398580:DSHI_RS09835
uniprot id: C5ZZD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

398580:DSHI RS15985
gene id: 398580:DSHI_RS15985
uniprot id: A8LLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS02750
gene id: 398580:DSHI_RS02750
uniprot id: A8LPG6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

398580:DSHI RS14235
gene id: 398580:DSHI_RS14235
uniprot id: A8LJ42
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

398580:DSHI RS05105
gene id: 398580:DSHI_RS05105
uniprot id: A8LSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell inner membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: Part of an energy-coupled inorganic carbon pump.

398580:DSHI RS15330
gene id: 398580:DSHI_RS15330
uniprot id: A8LKH1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

398580:DSHI RS02325
gene id: 398580:DSHI_RS02325
uniprot id: A8LNP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

398580:DSHI RS10575
gene id: 398580:DSHI_RS10575
uniprot id: A8LPW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

398580:DSHI RS17335
gene id: 398580:DSHI_RS17335
uniprot id: A8LP91
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

398580:DSHI RS17200
gene id: 398580:DSHI_RS17200
uniprot id: A8LNN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS07810
gene id: 398580:DSHI_RS07810
uniprot id: A8LK77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

398580:DSHI RS02315
gene id: 398580:DSHI_RS02315
uniprot id: A8LNP2
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

398580:DSHI RS03505
gene id: 398580:DSHI_RS03505
uniprot id: A8LQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

398580:DSHI RS08145
gene id: 398580:DSHI_RS08145
uniprot id: A8LKX9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

398580:DSHI RS20380
gene id: 398580:DSHI_RS20380
uniprot id: A8LTD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS18085
gene id: 398580:DSHI_RS18085
uniprot id: A8LQ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

398580:DSHI RS04235
gene id: 398580:DSHI_RS04235
uniprot id: A8LRC2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

398580:DSHI RS10315
gene id: 398580:DSHI_RS10315
uniprot id: A8LPQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS22615
gene id: 398580:DSHI_RS22615
uniprot id: A8LSU8
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

398580:DSHI RS18245
gene id: 398580:DSHI_RS18245
uniprot id: A8LSX0
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS20920
gene id: 398580:DSHI_RS20920
uniprot id: A8LUG2
names: Subcellular Location Annotation
messages: Cell membrane

398580:DSHI RS10740
gene id: 398580:DSHI_RS10740
uniprot id: A8LQI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

398580:DSHI RS04120
gene id: 398580:DSHI_RS04120
uniprot id: A8LR08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

398580:DSHI RS13845
gene id: 398580:DSHI_RS13845
uniprot id: A8LIL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

398580:DSHI RS14175
gene id: 398580:DSHI_RS14175
uniprot id: A8LJ30
names: Similarity
messages: Belongs to the TelA family.

398580:DSHI RS09825
gene id: 398580:DSHI_RS09825
uniprot id: A8LNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

398580:DSHI RS00955
gene id: 398580:DSHI_RS00955
uniprot id: A8LLD1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

398580:DSHI RS17375
gene id: 398580:DSHI_RS17375
uniprot id: A8LP99
names: Similarity
messages: Belongs to the SCO1/2 family.

398580:DSHI RS14435
gene id: 398580:DSHI_RS14435
uniprot id: A8LJ82
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS16055
gene id: 398580:DSHI_RS16055
uniprot id: A8LLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

398580:DSHI RS07205
gene id: 398580:DSHI_RS07205
uniprot id: A8LJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS10355
gene id: 398580:DSHI_RS10355
uniprot id: A8LPR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS00350
gene id: 398580:DSHI_RS00350
uniprot id: A8LJZ6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

398580:DSHI RS01720
gene id: 398580:DSHI_RS01720
uniprot id: A8LMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

398580:DSHI RS04285
gene id: 398580:DSHI_RS04285
uniprot id: A8LRD2
names: Similarity
messages: Belongs to the GST superfamily.

398580:DSHI RS08395
gene id: 398580:DSHI_RS08395
uniprot id: A8LLL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

398580:DSHI RS07835
gene id: 398580:DSHI_RS07835
uniprot id: A8LK82
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS13980
gene id: 398580:DSHI_RS13980
uniprot id: A8LIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS01810
gene id: 398580:DSHI_RS01810
uniprot id: A8LMD3
names: Similarity
messages: Belongs to the peptidase M16 family.

398580:DSHI RS02805
gene id: 398580:DSHI_RS02805
uniprot id: A8LPH7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

398580:DSHI RS13350
gene id: 398580:DSHI_RS13350
uniprot id: A8LI29
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

398580:DSHI RS16855
gene id: 398580:DSHI_RS16855
uniprot id: A8LNG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS06770
gene id: 398580:DSHI_RS06770
uniprot id: A8LIV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS20525
gene id: 398580:DSHI_RS20525
uniprot id: A8LT46
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

398580:DSHI RS00545
gene id: 398580:DSHI_RS00545
uniprot id: A8LKL6
names: Similarity
messages: Belongs to the UPF0178 family.

398580:DSHI RS18565
gene id: 398580:DSHI_RS18565
uniprot id: A8LT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

398580:DSHI RS03355
gene id: 398580:DSHI_RS03355
uniprot id: A8LQB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS15270
gene id: 398580:DSHI_RS15270
uniprot id: A8LKF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS02230
gene id: 398580:DSHI_RS02230
uniprot id: A8LN39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

398580:DSHI RS12010
gene id: 398580:DSHI_RS12010
uniprot id: A8LRR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

398580:DSHI RS20875
gene id: 398580:DSHI_RS20875
uniprot id: A8LUF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.

398580:DSHI RS17580
gene id: 398580:DSHI_RS17580
uniprot id: A8LPE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

398580:DSHI RS16450
gene id: 398580:DSHI_RS16450
uniprot id: A8LMQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

398580:DSHI RS13540
gene id: 398580:DSHI_RS13540
uniprot id: A8LI67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS02925
gene id: 398580:DSHI_RS02925
uniprot id: A8LPJ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS16160
gene id: 398580:DSHI_RS16160
uniprot id: A8LM12
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS12385
gene id: 398580:DSHI_RS12385
uniprot id: A8LS75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

398580:DSHI RS13260
gene id: 398580:DSHI_RS13260
uniprot id: A8LI11
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

398580:DSHI RS16480
gene id: 398580:DSHI_RS16480
uniprot id: A8LMR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

398580:DSHI RS12690
gene id: 398580:DSHI_RS12690
uniprot id: A8LSN0
names: Subcellular Location Annotation
messages: Cell membrane

398580:DSHI RS03325
gene id: 398580:DSHI_RS03325
uniprot id: A8LQB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

398580:DSHI RS14650
gene id: 398580:DSHI_RS14650
uniprot id: A8LJL7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

398580:DSHI RS14365
gene id: 398580:DSHI_RS14365
uniprot id: A8LJ68
names: Similarity
messages: Belongs to the UPF0102 family.

398580:DSHI RS00895
gene id: 398580:DSHI_RS00895
uniprot id: A8LLB9
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

398580:DSHI RS19350
gene id: 398580:DSHI_RS19350
uniprot id: A8LTJ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

398580:DSHI RS01715
gene id: 398580:DSHI_RS01715
uniprot id: A8LMB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

398580:DSHI RS05300
gene id: 398580:DSHI_RS05300
uniprot id: A8LSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS06530
gene id: 398580:DSHI_RS06530
uniprot id: A8LIQ9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

398580:DSHI RS08275
gene id: 398580:DSHI_RS08275
uniprot id: A8LL04
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

398580:DSHI RS20790
gene id: 398580:DSHI_RS20790
uniprot id: A8LUD6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

398580:DSHI RS13065
gene id: 398580:DSHI_RS13065
uniprot id: A8LSV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS16900
gene id: 398580:DSHI_RS16900
uniprot id: A8LNH3
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

398580:DSHI RS09345
gene id: 398580:DSHI_RS09345
uniprot id: A8LN60
names: Similarity
messages: Belongs to the universal stress protein A family.

398580:DSHI RS08230
gene id: 398580:DSHI_RS08230
uniprot id: A8LKZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

398580:DSHI RS18480
gene id: 398580:DSHI_RS18480
uniprot id: A8LT19
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: Single-chain monomer with multiple functions.

398580:DSHI RS20675
gene id: 398580:DSHI_RS20675
uniprot id: A8LUB7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

398580:DSHI RS03020
gene id: 398580:DSHI_RS03020
uniprot id: A8LPL7
names: Similarity
messages: Belongs to the MreC family.

398580:DSHI RS15230
gene id: 398580:DSHI_RS15230
uniprot id: A8LKF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS01365
gene id: 398580:DSHI_RS01365
uniprot id: A8LLG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

398580:DSHI RS06050
gene id: 398580:DSHI_RS06050
uniprot id: A8LI73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

398580:DSHI RS06960
gene id: 398580:DSHI_RS06960
uniprot id: A8LIZ5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

398580:DSHI RS00985
gene id: 398580:DSHI_RS00985
uniprot id: A8LLD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

398580:DSHI RS15090
gene id: 398580:DSHI_RS15090
uniprot id: A8LKC5
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

398580:DSHI RS06260
gene id: 398580:DSHI_RS06260
uniprot id: A8LIB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

398580:DSHI RS05005
gene id: 398580:DSHI_RS05005
uniprot id: A8LS14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

398580:DSHI RS05205
gene id: 398580:DSHI_RS05205
uniprot id: A8LSE4
names: Similarity
messages: Belongs to the PhoH family.

398580:DSHI RS04790
gene id: 398580:DSHI_RS04790
uniprot id: A8LRX4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

398580:DSHI RS19910
gene id: 398580:DSHI_RS19910
uniprot id: A8LSY1
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS10795
gene id: 398580:DSHI_RS10795
uniprot id: A8LQJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS10800
gene id: 398580:DSHI_RS10800
uniprot id: A8LQJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS09190
gene id: 398580:DSHI_RS09190
uniprot id: A8LMK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

398580:DSHI RS17600
gene id: 398580:DSHI_RS17600
uniprot id: A8LPE5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

398580:DSHI RS09460
gene id: 398580:DSHI_RS09460
uniprot id: A8LN83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

398580:DSHI RS15435
gene id: 398580:DSHI_RS15435
uniprot id: A8LL26
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

398580:DSHI RS20340
gene id: 398580:DSHI_RS20340
uniprot id: A8LTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

398580:DSHI RS09005
gene id: 398580:DSHI_RS09005
uniprot id: A8LMG5
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

398580:DSHI RS02055
gene id: 398580:DSHI_RS02055
uniprot id: A8LN06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

398580:DSHI RS08575
gene id: 398580:DSHI_RS08575
uniprot id: A8LLP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS14620
gene id: 398580:DSHI_RS14620
uniprot id: A8LJL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

398580:DSHI RS08360
gene id: 398580:DSHI_RS08360
uniprot id: A8LL20
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

398580:DSHI RS05570
gene id: 398580:DSHI_RS05570
uniprot id: A8LHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS11605
gene id: 398580:DSHI_RS11605
uniprot id: A8LR96
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

398580:DSHI RS10910
gene id: 398580:DSHI_RS10910
uniprot id: A8LQL3
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

398580:DSHI RS00835
gene id: 398580:DSHI_RS00835
uniprot id: A8LKS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS01635
gene id: 398580:DSHI_RS01635
uniprot id: A8LMA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

398580:DSHI RS01595
gene id: 398580:DSHI_RS01595
uniprot id: A8LM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

398580:DSHI RS13930
gene id: 398580:DSHI_RS13930
uniprot id: A8LIN6
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

398580:DSHI RS17085
gene id: 398580:DSHI_RS17085
uniprot id: A8LNL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

398580:DSHI RS16190
gene id: 398580:DSHI_RS16190
uniprot id: A8LM18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

398580:DSHI RS14815
gene id: 398580:DSHI_RS14815
uniprot id: A8LJQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

398580:DSHI RS10965
gene id: 398580:DSHI_RS10965
uniprot id: A8LQM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS01510
gene id: 398580:DSHI_RS01510
uniprot id: A8LM75
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

398580:DSHI RS00190
gene id: 398580:DSHI_RS00190
uniprot id: A8LJW2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

398580:DSHI RS02795
gene id: 398580:DSHI_RS02795
uniprot id: A8LPH5
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

398580:DSHI RS17885
gene id: 398580:DSHI_RS17885
uniprot id: A8LQ27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

398580:DSHI RS21935
gene id: 398580:DSHI_RS21935
uniprot id: A8LTB3
names: Similarity
messages: Belongs to the RelE toxin family.

398580:DSHI RS08700
gene id: 398580:DSHI_RS08700
uniprot id: A8LLS4
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

398580:DSHI RS03170
gene id: 398580:DSHI_RS03170
uniprot id: A8LPP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

398580:DSHI RS14705
gene id: 398580:DSHI_RS14705
uniprot id: A8LJM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

398580:DSHI RS16535
gene id: 398580:DSHI_RS16535
uniprot id: A8LMS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

398580:DSHI RS01945
gene id: 398580:DSHI_RS01945
uniprot id: A8LMZ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

398580:DSHI RS05770
gene id: 398580:DSHI_RS05770
uniprot id: A8LHS4
names: Similarity
messages: Belongs to the bacterial secretin family.

398580:DSHI RS16930
gene id: 398580:DSHI_RS16930
uniprot id: A8LNH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

398580:DSHI RS01745
gene id: 398580:DSHI_RS01745
uniprot id: A8LMC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

398580:DSHI RS17750
gene id: 398580:DSHI_RS17750
uniprot id: A8LQ00
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

398580:DSHI RS19380
gene id: 398580:DSHI_RS19380
uniprot id: A8LTK4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

398580:DSHI RS17090
gene id: 398580:DSHI_RS17090
uniprot id: A8LNL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

398580:DSHI RS21220
gene id: 398580:DSHI_RS21220
uniprot id: A8LLJ6
names: Similarity
messages: Belongs to the peptidase S8 family.

398580:DSHI RS01815
gene id: 398580:DSHI_RS01815
uniprot id: A8LMD4
names: Similarity
messages: Belongs to the peptidase M16 family.

398580:DSHI RS04070
gene id: 398580:DSHI_RS04070
uniprot id: A8LQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

398580:DSHI RS17285
gene id: 398580:DSHI_RS17285
uniprot id: A8LP81
names: Similarity
messages: Belongs to the YciI family.

398580:DSHI RS16470
gene id: 398580:DSHI_RS16470
uniprot id: A8LMQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

398580:DSHI RS11475
gene id: 398580:DSHI_RS11475
uniprot id: A8LR71
names: Similarity
messages: Belongs to the UPF0047 family.

398580:DSHI RS06690
gene id: 398580:DSHI_RS06690
uniprot id: A8LIU1
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

398580:DSHI RS09695
gene id: 398580:DSHI_RS09695
uniprot id: A8LND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

398580:DSHI RS11305
gene id: 398580:DSHI_RS11305
uniprot id: A8LR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS00560
gene id: 398580:DSHI_RS00560
uniprot id: A8LKL9
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

398580:DSHI RS02060
gene id: 398580:DSHI_RS02060
uniprot id: A8LN07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

398580:DSHI RS02680
gene id: 398580:DSHI_RS02680
uniprot id: A8LNW7
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS10395
gene id: 398580:DSHI_RS10395
uniprot id: A8LPS5
names: Similarity
messages: Belongs to the universal stress protein A family.

398580:DSHI RS04130
gene id: 398580:DSHI_RS04130
uniprot id: A8LR10
names: Similarity
messages: Belongs to the MipA/OmpV family.

398580:DSHI RS13130
gene id: 398580:DSHI_RS13130
uniprot id: A8LHY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

398580:DSHI RS09525
gene id: 398580:DSHI_RS09525
uniprot id: A8LN97
names: Similarity
messages: Belongs to the glutamate synthase family.

398580:DSHI RS01100
gene id: 398580:DSHI_RS01100
uniprot id: A8LLG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

398580:DSHI RS03930
gene id: 398580:DSHI_RS03930
uniprot id: A8LQX1
names: Subcellular Location Annotation
messages: Cytoplasm

398580:DSHI RS02215
gene id: 398580:DSHI_RS02215
uniprot id: A8LN37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS07540
gene id: 398580:DSHI_RS07540
uniprot id: A8LK24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS00115
gene id: 398580:DSHI_RS00115
uniprot id: A8LJU7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

398580:DSHI RS10295
gene id: 398580:DSHI_RS10295
uniprot id: A8LPQ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

398580:DSHI RS14300
gene id: 398580:DSHI_RS14300
uniprot id: A8LJ55
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

398580:DSHI RS04800
gene id: 398580:DSHI_RS04800
uniprot id: A8LRX6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS06285
gene id: 398580:DSHI_RS06285
uniprot id: A8LIC0
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS03330
gene id: 398580:DSHI_RS03330
uniprot id: A8LQB1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

398580:DSHI RS13975
gene id: 398580:DSHI_RS13975
uniprot id: A8LIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS15095
gene id: 398580:DSHI_RS15095
uniprot id: A8LKC6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS04295
gene id: 398580:DSHI_RS04295
uniprot id: A8LRD4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS01495
gene id: 398580:DSHI_RS01495
uniprot id: A8LM72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

398580:DSHI RS11095
gene id: 398580:DSHI_RS11095
uniprot id: A8LQP9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

398580:DSHI RS16145
gene id: 398580:DSHI_RS16145
uniprot id: A8LM09
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

398580:DSHI RS05335
gene id: 398580:DSHI_RS05335
uniprot id: A8LSH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS11115
gene id: 398580:DSHI_RS11115
uniprot id: A8LQQ3
names: Subcellular Location Annotation
messages: Cell membrane

398580:DSHI RS08330
gene id: 398580:DSHI_RS08330
uniprot id: A8LL14
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS06235
gene id: 398580:DSHI_RS06235
uniprot id: A8LIA9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

398580:DSHI RS17535
gene id: 398580:DSHI_RS17535
uniprot id: A8LPD2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

398580:DSHI RS08790
gene id: 398580:DSHI_RS08790
uniprot id: A8LLU0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

398580:DSHI RS16710
gene id: 398580:DSHI_RS16710
uniprot id: A8LMV5
names: Similarity
messages: Belongs to the histone deacetylase family.

398580:DSHI RS04110
gene id: 398580:DSHI_RS04110
uniprot id: A8LR06
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

398580:DSHI RS02260
gene id: 398580:DSHI_RS02260
uniprot id: A8LN45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

398580:DSHI RS00430
gene id: 398580:DSHI_RS00430
uniprot id: A8LKJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

398580:DSHI RS07210
gene id: 398580:DSHI_RS07210
uniprot id: A8LJD6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS17595
gene id: 398580:DSHI_RS17595
uniprot id: A8LPE4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

398580:DSHI RS13900
gene id: 398580:DSHI_RS13900
uniprot id: A8LIN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

398580:DSHI RS05115
gene id: 398580:DSHI_RS05115
uniprot id: A8LSC6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

398580:DSHI RS20745
gene id: 398580:DSHI_RS20745
uniprot id: A8LUC7
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus membrane

398580:DSHI RS11765
gene id: 398580:DSHI_RS11765
uniprot id: A8LRL8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

398580:DSHI RS16645
gene id: 398580:DSHI_RS16645
uniprot id: A8LMU2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

398580:DSHI RS18070
gene id: 398580:DSHI_RS18070
uniprot id: A8LQ64
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

398580:DSHI RS08335
gene id: 398580:DSHI_RS08335
uniprot id: A8LL15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

398580:DSHI RS15690
gene id: 398580:DSHI_RS15690
uniprot id: A8LL79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

398580:DSHI RS13605
gene id: 398580:DSHI_RS13605
uniprot id: A8LIH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

398580:DSHI RS16085
gene id: 398580:DSHI_RS16085
uniprot id: A8LLZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Involved in heme d1 biosynthesis (PubMed:29076625). Radical SAM enzyme that catalyzes the removal of two propionate side chains from the intermediate 12,18-didecarboxysiroheme (DDSH) and may introduce the keto functions on rings A and B, yielding the heme d1 precursor dihydro-heme d1 (PubMed:29076625).

398580:DSHI RS05640
gene id: 398580:DSHI_RS05640
uniprot id: A8LHP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

398580:DSHI RS06455
gene id: 398580:DSHI_RS06455
uniprot id: A8LIF4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

398580:DSHI RS07195
gene id: 398580:DSHI_RS07195
uniprot id: A8LJD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

398580:DSHI RS14110
gene id: 398580:DSHI_RS14110
uniprot id: A8LJ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

398580:DSHI RS11920
gene id: 398580:DSHI_RS11920
uniprot id: A8LRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

398580:DSHI RS03005
gene id: 398580:DSHI_RS03005
uniprot id: A8LPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

398580:DSHI RS16670
gene id: 398580:DSHI_RS16670
uniprot id: A8LMU7
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

398580:DSHI RS11900
gene id: 398580:DSHI_RS11900
uniprot id: A8LRP4
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

398580:DSHI RS11470
gene id: 398580:DSHI_RS11470
uniprot id: A8LR70
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

398580:DSHI RS18310
gene id: 398580:DSHI_RS18310
uniprot id: A8LSY4
names: Similarity
messages: Belongs to the SCO1/2 family.

398580:DSHI RS14975
gene id: 398580:DSHI_RS14975
uniprot id: A8LKA2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

398580:DSHI RS13215
gene id: 398580:DSHI_RS13215
uniprot id: A8LI02
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

398580:DSHI RS04135
gene id: 398580:DSHI_RS04135
uniprot id: A8LR11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

398580:DSHI RS08985
gene id: 398580:DSHI_RS08985
uniprot id: A8LMG2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS20865
gene id: 398580:DSHI_RS20865
uniprot id: A8LUF1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

398580:DSHI RS00395
gene id: 398580:DSHI_RS00395
uniprot id: A8LKI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS14280
gene id: 398580:DSHI_RS14280
uniprot id: A8LJ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

398580:DSHI RS07815
gene id: 398580:DSHI_RS07815
uniprot id: A8LK78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS16380
gene id: 398580:DSHI_RS16380
uniprot id: A8LMP1
names: Similarity
messages: Belongs to the peptidase C40 family.

398580:DSHI RS14520
gene id: 398580:DSHI_RS14520
uniprot id: A8LJJ1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

398580:DSHI RS16140
gene id: 398580:DSHI_RS16140
uniprot id: A8LM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

398580:DSHI RS10755
gene id: 398580:DSHI_RS10755
uniprot id: A8LQI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS02790
gene id: 398580:DSHI_RS02790
uniprot id: A8LPH4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

398580:DSHI RS04855
gene id: 398580:DSHI_RS04855
uniprot id: A8LRY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

398580:DSHI RS07060
gene id: 398580:DSHI_RS07060
uniprot id: A8LJA7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

398580:DSHI RS06055
gene id: 398580:DSHI_RS06055
uniprot id: A8LI74
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

398580:DSHI RS15340
gene id: 398580:DSHI_RS15340
uniprot id: A8LKH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

398580:DSHI RS15640
gene id: 398580:DSHI_RS15640
uniprot id: A8LL69
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

398580:DSHI RS00070
gene id: 398580:DSHI_RS00070
uniprot id: A8LJT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

398580:DSHI RS16865
gene id: 398580:DSHI_RS16865
uniprot id: A8LNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS06080
gene id: 398580:DSHI_RS06080
uniprot id: A8LI79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

398580:DSHI RS01355
gene id: 398580:DSHI_RS01355
uniprot id: A8LM44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

398580:DSHI RS03485
gene id: 398580:DSHI_RS03485
uniprot id: A8LQE1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

398580:DSHI RS06705
gene id: 398580:DSHI_RS06705
uniprot id: A8LIU4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

398580:DSHI RS12570
gene id: 398580:DSHI_RS12570
uniprot id: A8LSB2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS05980
gene id: 398580:DSHI_RS05980
uniprot id: A8LHW6
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

398580:DSHI RS06840
gene id: 398580:DSHI_RS06840
uniprot id: A8LIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

398580:DSHI RS03480
gene id: 398580:DSHI_RS03480
uniprot id: A8LQE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

398580:DSHI RS20125
gene id: 398580:DSHI_RS20125
uniprot id: A8LU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

398580:DSHI RS11715
gene id: 398580:DSHI_RS11715
uniprot id: A8LRK9
names: Subcellular Location Annotation
messages: Cytoplasm

398580:DSHI RS00715
gene id: 398580:DSHI_RS00715
uniprot id: A8LKQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS17035
gene id: 398580:DSHI_RS17035
uniprot id: A8LNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

398580:DSHI RS00995
gene id: 398580:DSHI_RS00995
uniprot id: A8LLD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

398580:DSHI RS17955
gene id: 398580:DSHI_RS17955
uniprot id: A8LQ41
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS07630
gene id: 398580:DSHI_RS07630
uniprot id: A8LK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

398580:DSHI RS11550
gene id: 398580:DSHI_RS11550
uniprot id: A8LR86
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

398580:DSHI RS15665
gene id: 398580:DSHI_RS15665
uniprot id: A8LL74
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

398580:DSHI RS08365
gene id: 398580:DSHI_RS08365
uniprot id: A8LLK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

398580:DSHI RS02150
gene id: 398580:DSHI_RS02150
uniprot id: A8LN26
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

398580:DSHI RS12055
gene id: 398580:DSHI_RS12055
uniprot id: A8LRS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

398580:DSHI RS06395
gene id: 398580:DSHI_RS06395
uniprot id: A8LIE2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

398580:DSHI RS16995
gene id: 398580:DSHI_RS16995
uniprot id: A8LNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

398580:DSHI RS08430
gene id: 398580:DSHI_RS08430
uniprot id: A8LLM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS00150
gene id: 398580:DSHI_RS00150
uniprot id: A8LJV4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

398580:DSHI RS09880
gene id: 398580:DSHI_RS09880
uniprot id: A8LNZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

398580:DSHI RS16475
gene id: 398580:DSHI_RS16475
uniprot id: A8LMR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

398580:DSHI RS04840
gene id: 398580:DSHI_RS04840
uniprot id: A8LRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

398580:DSHI RS03165
gene id: 398580:DSHI_RS03165
uniprot id: A8LPP6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

398580:DSHI RS16235
gene id: 398580:DSHI_RS16235
uniprot id: A8LM27
names: Subunit
messages: Homodimer.

398580:DSHI RS09615
gene id: 398580:DSHI_RS09615
uniprot id: A8LNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

398580:DSHI RS05580
gene id: 398580:DSHI_RS05580
uniprot id: A8LHN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS08740
gene id: 398580:DSHI_RS08740
uniprot id: A8LLT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

398580:DSHI RS19700
gene id: 398580:DSHI_RS19700
uniprot id: A8LTR8
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS06790
gene id: 398580:DSHI_RS06790
uniprot id: A8LIW1
names: Similarity
messages: Belongs to the DEAD box helicase family.

398580:DSHI RS20950
gene id: 398580:DSHI_RS20950
uniprot id: A8LUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

398580:DSHI RS09355
gene id: 398580:DSHI_RS09355
uniprot id: A8LN62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS19015
gene id: 398580:DSHI_RS19015
uniprot id: A8LTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

398580:DSHI RS09390
gene id: 398580:DSHI_RS09390
uniprot id: A8LN68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

398580:DSHI RS19120
gene id: 398580:DSHI_RS19120
uniprot id: A8LTF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

398580:DSHI RS09665
gene id: 398580:DSHI_RS09665
uniprot id: A8LNC5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

398580:DSHI RS07980
gene id: 398580:DSHI_RS07980
uniprot id: A8LKU6
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS01320
gene id: 398580:DSHI_RS01320
uniprot id: A8LLK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

398580:DSHI RS13885
gene id: 398580:DSHI_RS13885
uniprot id: A8LIM7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

398580:DSHI RS13735
gene id: 398580:DSHI_RS13735
uniprot id: A8LIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS01900
gene id: 398580:DSHI_RS01900
uniprot id: A8LMY4
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS15235
gene id: 398580:DSHI_RS15235
uniprot id: A8LKF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS08445
gene id: 398580:DSHI_RS08445
uniprot id: A8LLM3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

398580:DSHI RS20245
gene id: 398580:DSHI_RS20245
uniprot id: A8LU41
names: Similarity
messages: Belongs to the ParB family.

398580:DSHI RS17865
gene id: 398580:DSHI_RS17865
uniprot id: A8LQ23
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS08925
gene id: 398580:DSHI_RS08925
uniprot id: A8LMF0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

398580:DSHI RS14760
gene id: 398580:DSHI_RS14760
uniprot id: A8LJN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

398580:DSHI RS03925
gene id: 398580:DSHI_RS03925
uniprot id: A8LQX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

398580:DSHI RS10030
gene id: 398580:DSHI_RS10030
uniprot id: A8LP26
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

398580:DSHI RS19180
gene id: 398580:DSHI_RS19180
uniprot id: A8LTG4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

398580:DSHI RS21095
gene id: 398580:DSHI_RS21095
uniprot id: A8LUJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS18015
gene id: 398580:DSHI_RS18015
uniprot id: A8LQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

398580:DSHI RS18425
gene id: 398580:DSHI_RS18425
uniprot id: A8LT07
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

398580:DSHI RS15375
gene id: 398580:DSHI_RS15375
uniprot id: A8LKI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a, b, b' and c.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

398580:DSHI RS10400
gene id: 398580:DSHI_RS10400
uniprot id: A8LPS6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS01340
gene id: 398580:DSHI_RS01340
uniprot id: A8LM41
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

398580:DSHI RS15990
gene id: 398580:DSHI_RS15990
uniprot id: A8LLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS19875
gene id: 398580:DSHI_RS19875
uniprot id: A8LSX3
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS06865
gene id: 398580:DSHI_RS06865
uniprot id: A8LIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS17095
gene id: 398580:DSHI_RS17095
uniprot id: A8LNL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

398580:DSHI RS03935
gene id: 398580:DSHI_RS03935
uniprot id: A8LQX2
names: Similarity
messages: Belongs to the ArsC family.

398580:DSHI RS00990
gene id: 398580:DSHI_RS00990
uniprot id: A8LLD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

398580:DSHI RS10070
gene id: 398580:DSHI_RS10070
uniprot id: A8LP33
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

398580:DSHI RS15835
gene id: 398580:DSHI_RS15835
uniprot id: A8LLA7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

398580:DSHI RS06540
gene id: 398580:DSHI_RS06540
uniprot id: A8LIR1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

398580:DSHI RS00780
gene id: 398580:DSHI_RS00780
uniprot id: A8LKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

398580:DSHI RS09920
gene id: 398580:DSHI_RS09920
uniprot id: A8LP05
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS13865
gene id: 398580:DSHI_RS13865
uniprot id: A8LIM3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

398580:DSHI RS03235
gene id: 398580:DSHI_RS03235
uniprot id: A8LQ92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

398580:DSHI RS00110
gene id: 398580:DSHI_RS00110
uniprot id: A8LJU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

398580:DSHI RS15885
gene id: 398580:DSHI_RS15885
uniprot id: A8LLV7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

398580:DSHI RS19150
gene id: 398580:DSHI_RS19150
uniprot id: A8LTF8
names: Subcellular Location Annotation
messages: Cell inner membrane

398580:DSHI RS03960
gene id: 398580:DSHI_RS03960
uniprot id: A8LQX7
names: Function
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.

398580:DSHI RS07035
gene id: 398580:DSHI_RS07035
uniprot id: A8LJA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS12585
gene id: 398580:DSHI_RS12585
uniprot id: A8LSB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

398580:DSHI RS01955
gene id: 398580:DSHI_RS01955
uniprot id: A8LMZ4
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS15550
gene id: 398580:DSHI_RS15550
uniprot id: A8LL50
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

398580:DSHI RS17120
gene id: 398580:DSHI_RS17120
uniprot id: A8LNL9
names: Similarity
messages: Belongs to the MotB family.

398580:DSHI RS08030
gene id: 398580:DSHI_RS08030
uniprot id: A8LKV6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

398580:DSHI RS18555
gene id: 398580:DSHI_RS18555
uniprot id: A8LT36
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS03055
gene id: 398580:DSHI_RS03055
uniprot id: A8LPM4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS07610
gene id: 398580:DSHI_RS07610
uniprot id: A8LK37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

398580:DSHI RS01470
gene id: 398580:DSHI_RS01470
uniprot id: A8LM67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

398580:DSHI RS18610
gene id: 398580:DSHI_RS18610
uniprot id: A8LT49
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

398580:DSHI RS16395
gene id: 398580:DSHI_RS16395
uniprot id: A8LMP4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

398580:DSHI RS14925
gene id: 398580:DSHI_RS14925
uniprot id: A8LJS2
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

398580:DSHI RS10020
gene id: 398580:DSHI_RS10020
uniprot id: A8LP24
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

398580:DSHI RS00305
gene id: 398580:DSHI_RS00305
uniprot id: A8LJY7
names: Similarity
messages: Belongs to the peptidase U62 family.

398580:DSHI RS05240
gene id: 398580:DSHI_RS05240
uniprot id: A8LSF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

398580:DSHI RS00665
gene id: 398580:DSHI_RS00665
uniprot id: A8LKP0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

398580:DSHI RS14590
gene id: 398580:DSHI_RS14590
uniprot id: A8LJK6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

398580:DSHI RS18745
gene id: 398580:DSHI_RS18745
uniprot id: A8LT74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS11905
gene id: 398580:DSHI_RS11905
uniprot id: A8LRP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

398580:DSHI RS01290
gene id: 398580:DSHI_RS01290
uniprot id: A8LLJ8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

398580:DSHI RS04885
gene id: 398580:DSHI_RS04885
uniprot id: A8LRZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS12675
gene id: 398580:DSHI_RS12675
uniprot id: A8LSM7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

398580:DSHI RS21170
gene id: 398580:DSHI_RS21170
uniprot id: A8LUL2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS07565
gene id: 398580:DSHI_RS07565
uniprot id: A8LK28
names: Similarity
messages: Belongs to the GcvT family.

398580:DSHI RS03320
gene id: 398580:DSHI_RS03320
uniprot id: A8LQA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

398580:DSHI RS10150
gene id: 398580:DSHI_RS10150
uniprot id: A8LP48
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS00585
gene id: 398580:DSHI_RS00585
uniprot id: A8LKM4
names: Similarity
messages: Belongs to the SfsA family.

398580:DSHI RS03795
gene id: 398580:DSHI_RS03795
uniprot id: A8LQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

398580:DSHI RS17430
gene id: 398580:DSHI_RS17430
uniprot id: A8LPB0
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS07725
gene id: 398580:DSHI_RS07725
uniprot id: A8LK60
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS21190
gene id: 398580:DSHI_RS21190
uniprot id: A8LUL6
names: Similarity
messages: Belongs to the Dps family.

398580:DSHI RS11135
gene id: 398580:DSHI_RS11135
uniprot id: A8LQQ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

398580:DSHI RS03940
gene id: 398580:DSHI_RS03940
uniprot id: A8LQX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

398580:DSHI RS07660
gene id: 398580:DSHI_RS07660
uniprot id: A8LK47
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

398580:DSHI RS18820
gene id: 398580:DSHI_RS18820
uniprot id: A8LT89
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS09380
gene id: 398580:DSHI_RS09380
uniprot id: A8LN66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS09700
gene id: 398580:DSHI_RS09700
uniprot id: A8LND2
names: Subcellular Location Annotation
messages: Periplasm

398580:DSHI RS05790
gene id: 398580:DSHI_RS05790
uniprot id: A8LHS8
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

398580:DSHI RS05610
gene id: 398580:DSHI_RS05610
uniprot id: A8LHP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

398580:DSHI RS11495
gene id: 398580:DSHI_RS11495
uniprot id: A8LR75
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

398580:DSHI RS09195
gene id: 398580:DSHI_RS09195
uniprot id: A8LMK1
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS16705
gene id: 398580:DSHI_RS16705
uniprot id: A8LMV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

398580:DSHI RS02310
gene id: 398580:DSHI_RS02310
uniprot id: A8LN55
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

398580:DSHI RS01590
gene id: 398580:DSHI_RS01590
uniprot id: A8LM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

398580:DSHI RS02265
gene id: 398580:DSHI_RS02265
uniprot id: A8LN46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12) (By similarity).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

398580:DSHI RS09480
gene id: 398580:DSHI_RS09480
uniprot id: A8LN87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

398580:DSHI RS06275
gene id: 398580:DSHI_RS06275
uniprot id: A8LIB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

398580:DSHI RS18815
gene id: 398580:DSHI_RS18815
uniprot id: A8LT88
names: Similarity
messages: Belongs to the leucine-binding protein family.

398580:DSHI RS09565
gene id: 398580:DSHI_RS09565
uniprot id: A8LNA5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

398580:DSHI RS16550
gene id: 398580:DSHI_RS16550
uniprot id: A8LMS4
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

398580:DSHI RS08480
gene id: 398580:DSHI_RS08480
uniprot id: A8LLN0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS16030
gene id: 398580:DSHI_RS16030
uniprot id: A8LLY6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor.
messages: Periplasm

398580:DSHI RS11490
gene id: 398580:DSHI_RS11490
uniprot id: A8LR74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

398580:DSHI RS20410
gene id: 398580:DSHI_RS20410
uniprot id: A8LTE4
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS10915
gene id: 398580:DSHI_RS10915
uniprot id: A8LQL4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

398580:DSHI RS15670
gene id: 398580:DSHI_RS15670
uniprot id: A8LL75
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

398580:DSHI RS05535
gene id: 398580:DSHI_RS05535
uniprot id: A8LSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

398580:DSHI RS15970
gene id: 398580:DSHI_RS15970
uniprot id: A8LLX4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS04635
gene id: 398580:DSHI_RS04635
uniprot id: A8LRU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS16215
gene id: 398580:DSHI_RS16215
uniprot id: A8LM23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.

398580:DSHI RS06735
gene id: 398580:DSHI_RS06735
uniprot id: A8LIV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS04995
gene id: 398580:DSHI_RS04995
uniprot id: A8LS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

398580:DSHI RS20930
gene id: 398580:DSHI_RS20930
uniprot id: A8LUG4
names: Subcellular Location Annotation
messages: Periplasm

398580:DSHI RS17910
gene id: 398580:DSHI_RS17910
uniprot id: A8LQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

398580:DSHI RS05660
gene id: 398580:DSHI_RS05660
uniprot id: A8LHQ2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

398580:DSHI RS09490
gene id: 398580:DSHI_RS09490
uniprot id: A8LN89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

398580:DSHI RS03515
gene id: 398580:DSHI_RS03515
uniprot id: A8LQE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS05280
gene id: 398580:DSHI_RS05280
uniprot id: A8LSF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

398580:DSHI RS16155
gene id: 398580:DSHI_RS16155
uniprot id: A8LM11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS05845
gene id: 398580:DSHI_RS05845
uniprot id: A8LHT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS14150
gene id: 398580:DSHI_RS14150
uniprot id: A8LJ25
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS00770
gene id: 398580:DSHI_RS00770
uniprot id: A8LKR1
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS14045
gene id: 398580:DSHI_RS14045
uniprot id: A8LJ04
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS00740
gene id: 398580:DSHI_RS00740
uniprot id: A8LKQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

398580:DSHI RS16385
gene id: 398580:DSHI_RS16385
uniprot id: A8LMP2
names: Similarity
messages: Belongs to the peptidase M17 family.

398580:DSHI RS12470
gene id: 398580:DSHI_RS12470
uniprot id: A8LS92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

398580:DSHI RS12040
gene id: 398580:DSHI_RS12040
uniprot id: A8LRS0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

398580:DSHI RS18620
gene id: 398580:DSHI_RS18620
uniprot id: A8LT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

398580:DSHI RS12725
gene id: 398580:DSHI_RS12725
uniprot id: A8LSN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

398580:DSHI RS15555
gene id: 398580:DSHI_RS15555
uniprot id: A8LL51
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

398580:DSHI RS09095
gene id: 398580:DSHI_RS09095
uniprot id: A8LMI2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

398580:DSHI RS05625
gene id: 398580:DSHI_RS05625
uniprot id: A8LHP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

398580:DSHI RS17105
gene id: 398580:DSHI_RS17105
uniprot id: A8LNL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

398580:DSHI RS01660
gene id: 398580:DSHI_RS01660
uniprot id: A8LMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

398580:DSHI RS03305
gene id: 398580:DSHI_RS03305
uniprot id: A8LQA6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

398580:DSHI RS12200
gene id: 398580:DSHI_RS12200
uniprot id: A8LS39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

398580:DSHI RS05235
gene id: 398580:DSHI_RS05235
uniprot id: A8LSF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

398580:DSHI RS08425
gene id: 398580:DSHI_RS08425
uniprot id: A8LLL9
names: Similarity
messages: Belongs to the bacterial glucokinase family.

398580:DSHI RS04355
gene id: 398580:DSHI_RS04355
uniprot id: A8LRE6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

398580:DSHI RS17055
gene id: 398580:DSHI_RS17055
uniprot id: A8LNK4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

398580:DSHI RS20520
gene id: 398580:DSHI_RS20520
uniprot id: A8LT47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

398580:DSHI RS11165
gene id: 398580:DSHI_RS11165
uniprot id: A8LQR4
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

398580:DSHI RS19185
gene id: 398580:DSHI_RS19185
uniprot id: A8LTG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS13145
gene id: 398580:DSHI_RS13145
uniprot id: A8LHY5
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

398580:DSHI RS16945
gene id: 398580:DSHI_RS16945
uniprot id: A8LNI2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

398580:DSHI RS01460
gene id: 398580:DSHI_RS01460
uniprot id: A8LM65
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

398580:DSHI RS04630
gene id: 398580:DSHI_RS04630
uniprot id: A8LRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

398580:DSHI RS17745
gene id: 398580:DSHI_RS17745
uniprot id: A8LPZ9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

398580:DSHI RS11440
gene id: 398580:DSHI_RS11440
uniprot id: A8LR64
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

398580:DSHI RS08195
gene id: 398580:DSHI_RS08195
uniprot id: A8LKY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

398580:DSHI RS20040
gene id: 398580:DSHI_RS20040
uniprot id: A8LU01
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

398580:DSHI RS19655
gene id: 398580:DSHI_RS19655
uniprot id: A8LTQ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

398580:DSHI RS19705
gene id: 398580:DSHI_RS19705
uniprot id: A8LTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

398580:DSHI RS10250
gene id: 398580:DSHI_RS10250
uniprot id: A8LP68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS17070
gene id: 398580:DSHI_RS17070
uniprot id: A8LNK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

398580:DSHI RS17900
gene id: 398580:DSHI_RS17900
uniprot id: A8LQ30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.

398580:DSHI RS01350
gene id: 398580:DSHI_RS01350
uniprot id: A8LM43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

398580:DSHI RS07945
gene id: 398580:DSHI_RS07945
uniprot id: A8LKT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

398580:DSHI RS01375
gene id: 398580:DSHI_RS01375
uniprot id: A8LM48
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

398580:DSHI RS13625
gene id: 398580:DSHI_RS13625
uniprot id: A8LIH7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

398580:DSHI RS02940
gene id: 398580:DSHI_RS02940
uniprot id: A8LPK2
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS18340
gene id: 398580:DSHI_RS18340
uniprot id: A8LSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

398580:DSHI RS05310
gene id: 398580:DSHI_RS05310
uniprot id: A8LSG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS18545
gene id: 398580:DSHI_RS18545
uniprot id: A8LT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

398580:DSHI RS15945
gene id: 398580:DSHI_RS15945
uniprot id: A8LLW9
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

398580:DSHI RS14880
gene id: 398580:DSHI_RS14880
uniprot id: A8LJR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

398580:DSHI RS14865
gene id: 398580:DSHI_RS14865
uniprot id: A8LJR0
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

398580:DSHI RS17140
gene id: 398580:DSHI_RS17140
uniprot id: A8LNM3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

398580:DSHI RS16905
gene id: 398580:DSHI_RS16905
uniprot id: A8LNH4
names: Similarity
messages: Belongs to the YggT family.

398580:DSHI RS07730
gene id: 398580:DSHI_RS07730
uniprot id: A8LK61
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS06230
gene id: 398580:DSHI_RS06230
uniprot id: A8LIA8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

398580:DSHI RS08455
gene id: 398580:DSHI_RS08455
uniprot id: A8LLM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS18445
gene id: 398580:DSHI_RS18445
uniprot id: A8LT12
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

398580:DSHI RS04245
gene id: 398580:DSHI_RS04245
uniprot id: A8LRC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

398580:DSHI RS17665
gene id: 398580:DSHI_RS17665
uniprot id: A8LPF8
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS03085
gene id: 398580:DSHI_RS03085
uniprot id: A8LPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS05685
gene id: 398580:DSHI_RS05685
uniprot id: A8LHQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

398580:DSHI RS17830
gene id: 398580:DSHI_RS17830
uniprot id: A8LQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Cellular chromatophore membrane
messages: Membrane
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

398580:DSHI RS09155
gene id: 398580:DSHI_RS09155
uniprot id: A8LMJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

398580:DSHI RS15980
gene id: 398580:DSHI_RS15980
uniprot id: A8LLX6
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

398580:DSHI RS15775
gene id: 398580:DSHI_RS15775
uniprot id: A8LL95
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

398580:DSHI RS04895
gene id: 398580:DSHI_RS04895
uniprot id: A8LRZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS04115
gene id: 398580:DSHI_RS04115
uniprot id: A8LR07
names: Similarity
messages: Belongs to the TPP enzyme family.

398580:DSHI RS00205
gene id: 398580:DSHI_RS00205
uniprot id: A8LJW5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

398580:DSHI RS20870
gene id: 398580:DSHI_RS20870
uniprot id: A8LUF2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

398580:DSHI RS17965
gene id: 398580:DSHI_RS17965
uniprot id: A8LQ43
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

398580:DSHI RS07535
gene id: 398580:DSHI_RS07535
uniprot id: A8LK23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS08375
gene id: 398580:DSHI_RS08375
uniprot id: A8LLK9
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS10945
gene id: 398580:DSHI_RS10945
uniprot id: A8LQM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS10810
gene id: 398580:DSHI_RS10810
uniprot id: A8LQJ3
names: Similarity
messages: Belongs to the creatininase superfamily.

398580:DSHI RS00435
gene id: 398580:DSHI_RS00435
uniprot id: A8LKJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

398580:DSHI RS03850
gene id: 398580:DSHI_RS03850
uniprot id: A8LQV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

398580:DSHI RS10270
gene id: 398580:DSHI_RS10270
uniprot id: A8LPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS07065
gene id: 398580:DSHI_RS07065
uniprot id: A8LJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

398580:DSHI RS06590
gene id: 398580:DSHI_RS06590
uniprot id: A8LIS1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

398580:DSHI RS07700
gene id: 398580:DSHI_RS07700
uniprot id: A8LK55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.

398580:DSHI RS00200
gene id: 398580:DSHI_RS00200
uniprot id: A8LJW4
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS06360
gene id: 398580:DSHI_RS06360
uniprot id: A8LID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS06805
gene id: 398580:DSHI_RS06805
uniprot id: A8LIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

398580:DSHI RS05230
gene id: 398580:DSHI_RS05230
uniprot id: A8LSE9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS14885
gene id: 398580:DSHI_RS14885
uniprot id: A8LJR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

398580:DSHI RS18770
gene id: 398580:DSHI_RS18770
uniprot id: A8LT79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS00620
gene id: 398580:DSHI_RS00620
uniprot id: A8LKN1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

398580:DSHI RS19685
gene id: 398580:DSHI_RS19685
uniprot id: A8LTR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

398580:DSHI RS07505
gene id: 398580:DSHI_RS07505
uniprot id: A8LK17
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

398580:DSHI RS12565
gene id: 398580:DSHI_RS12565
uniprot id: A8LSB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

398580:DSHI RS08975
gene id: 398580:DSHI_RS08975
uniprot id: A8LMG0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS01430
gene id: 398580:DSHI_RS01430
uniprot id: A8LM59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

398580:DSHI RS01155
gene id: 398580:DSHI_RS01155
uniprot id: A8LLH0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

398580:DSHI RS01520
gene id: 398580:DSHI_RS01520
uniprot id: A8LM77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

398580:DSHI RS17250
gene id: 398580:DSHI_RS17250
uniprot id: A8LP74
names: Similarity
messages: Belongs to the YkuD family.

398580:DSHI RS17800
gene id: 398580:DSHI_RS17800
uniprot id: A8LQ10
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

398580:DSHI RS08205
gene id: 398580:DSHI_RS08205
uniprot id: A8LKZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

398580:DSHI RS01425
gene id: 398580:DSHI_RS01425
uniprot id: A8LM58
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

398580:DSHI RS19900
gene id: 398580:DSHI_RS19900
uniprot id: A8LSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS19955
gene id: 398580:DSHI_RS19955
uniprot id: A8LSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

398580:DSHI RS08045
gene id: 398580:DSHI_RS08045
uniprot id: A8LKV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

398580:DSHI RS17980
gene id: 398580:DSHI_RS17980
uniprot id: A8LQ46
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

398580:DSHI RS06640
gene id: 398580:DSHI_RS06640
uniprot id: A8LIT1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

398580:DSHI RS09690
gene id: 398580:DSHI_RS09690
uniprot id: A8LND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

398580:DSHI RS05405
gene id: 398580:DSHI_RS05405
uniprot id: A8LSI4
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

398580:DSHI RS19055
gene id: 398580:DSHI_RS19055
uniprot id: A8LTD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS04105
gene id: 398580:DSHI_RS04105
uniprot id: A8LR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

398580:DSHI RS16810
gene id: 398580:DSHI_RS16810
uniprot id: A8LNF6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

398580:DSHI RS09870
gene id: 398580:DSHI_RS09870
uniprot id: A8LNZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

398580:DSHI RS16050
gene id: 398580:DSHI_RS16050
uniprot id: A8LLZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

398580:DSHI RS01140
gene id: 398580:DSHI_RS01140
uniprot id: A8LLG7
names: Similarity
messages: Belongs to the pyruvate kinase family.

398580:DSHI RS18410
gene id: 398580:DSHI_RS18410
uniprot id: A8LT04
names: Similarity
messages: Belongs to the virb1 family.

398580:DSHI RS15195
gene id: 398580:DSHI_RS15195
uniprot id: A8LKE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

398580:DSHI RS08220
gene id: 398580:DSHI_RS08220
uniprot id: A8LKZ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

398580:DSHI RS01200
gene id: 398580:DSHI_RS01200
uniprot id: A8LLH9
names: Similarity
messages: Belongs to the GST superfamily.

398580:DSHI RS16610
gene id: 398580:DSHI_RS16610
uniprot id: A8LMT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Cell membrane
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

398580:DSHI RS20080
gene id: 398580:DSHI_RS20080
uniprot id: A8LU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

398580:DSHI RS00280
gene id: 398580:DSHI_RS00280
uniprot id: A8LJY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

398580:DSHI RS06210
gene id: 398580:DSHI_RS06210
uniprot id: A8LIA4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

398580:DSHI RS04250
gene id: 398580:DSHI_RS04250
uniprot id: A8LRC5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

398580:DSHI RS06745
gene id: 398580:DSHI_RS06745
uniprot id: A8LIV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

398580:DSHI RS14100
gene id: 398580:DSHI_RS14100
uniprot id: A8LJ15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

398580:DSHI RS09225
gene id: 398580:DSHI_RS09225
uniprot id: A8LMK7
names: Subcellular Location Annotation
messages: Membrane

398580:DSHI RS08390
gene id: 398580:DSHI_RS08390
uniprot id: A8LLL2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

398580:DSHI RS04015
gene id: 398580:DSHI_RS04015
uniprot id: A8LQY7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

398580:DSHI RS17895
gene id: 398580:DSHI_RS17895
uniprot id: A8LQ29
names: Similarity
messages: Belongs to the Mg-chelatase subunit H family.

398580:DSHI RS11300
gene id: 398580:DSHI_RS11300
uniprot id: A8LR36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS03830
gene id: 398580:DSHI_RS03830
uniprot id: A8LQV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

398580:DSHI RS00040
gene id: 398580:DSHI_RS00040
uniprot id: A8LJT2
names: Subcellular Location Annotation
messages: Cytoplasm

398580:DSHI RS17945
gene id: 398580:DSHI_RS17945
uniprot id: A8LQ39
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

398580:DSHI RS01555
gene id: 398580:DSHI_RS01555
uniprot id: A8LM84
names: Similarity
messages: Belongs to the autoinducer synthase family.

398580:DSHI RS02640
gene id: 398580:DSHI_RS02640
uniprot id: A8LNV9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

398580:DSHI RS13890
gene id: 398580:DSHI_RS13890
uniprot id: A8LIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

398580:DSHI RS16860
gene id: 398580:DSHI_RS16860
uniprot id: A8LNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

398580:DSHI RS05170
gene id: 398580:DSHI_RS05170
uniprot id: A8LSD7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

398580:DSHI RS07580
gene id: 398580:DSHI_RS07580
uniprot id: A8LK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

398580:DSHI RS11580
gene id: 398580:DSHI_RS11580
uniprot id: A8LR91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

398580:DSHI RS17565
gene id: 398580:DSHI_RS17565
uniprot id: A8LPD8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

398580:DSHI RS08920
gene id: 398580:DSHI_RS08920
uniprot id: A8LME9
names: Similarity
messages: Belongs to the HIBADH-related family.

398580:DSHI RS11325
gene id: 398580:DSHI_RS11325
uniprot id: A8LR41
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

398580:DSHI RS11100
gene id: 398580:DSHI_RS11100
uniprot id: A8LQQ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

398580:DSHI RS11740
gene id: 398580:DSHI_RS11740
uniprot id: A8LRL4
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

398580:DSHI RS10870
gene id: 398580:DSHI_RS10870
uniprot id: A8LQK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

398580:DSHI RS22040
gene id: 398580:DSHI_RS22040
uniprot id: A8LTF1
names: Subcellular Location Annotation
messages: Cell membrane

398580:DSHI RS13745
gene id: 398580:DSHI_RS13745
uniprot id: A8LIJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

398580:DSHI RS16635
gene id: 398580:DSHI_RS16635
uniprot id: A8LMU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

398580:DSHI RS03030
gene id: 398580:DSHI_RS03030
uniprot id: A8LPL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

398580:DSHI RS00130
gene id: 398580:DSHI_RS00130
uniprot id: A8LJV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane