397948:CMAQ RS08835
gene id: 397948:CMAQ_RS08835
uniprot id: A8MAG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

397948:CMAQ RS09465
gene id: 397948:CMAQ_RS09465
uniprot id: A8MB26
names: Similarity
messages: Belongs to the carbamate kinase family.

397948:CMAQ RS09215
gene id: 397948:CMAQ_RS09215
uniprot id: A8MAY7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

397948:CMAQ RS04410
gene id: 397948:CMAQ_RS04410
uniprot id: A8MD44
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase 2 family.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

397948:CMAQ RS03360
gene id: 397948:CMAQ_RS03360
uniprot id: A8MCJ5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

397948:CMAQ RS01520
gene id: 397948:CMAQ_RS01520
uniprot id: A8MAV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

397948:CMAQ RS05270
gene id: 397948:CMAQ_RS05270
uniprot id: A8MDK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS09435
gene id: 397948:CMAQ_RS09435
uniprot id: A8MB21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

397948:CMAQ RS01525
gene id: 397948:CMAQ_RS01525
uniprot id: A8MAV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

397948:CMAQ RS07950
gene id: 397948:CMAQ_RS07950
uniprot id: A8M9F0
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

397948:CMAQ RS03670
gene id: 397948:CMAQ_RS03670
uniprot id: A8MCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

397948:CMAQ RS02465
gene id: 397948:CMAQ_RS02465
uniprot id: A8MBY5
names: Similarity
messages: Belongs to the UPF0273 family.

397948:CMAQ RS02580
gene id: 397948:CMAQ_RS02580
uniprot id: A8MC44
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS06980
gene id: 397948:CMAQ_RS06980
uniprot id: A8M8W6
names: Similarity
messages: Belongs to the eIF-2-alpha family.

397948:CMAQ RS01900
gene id: 397948:CMAQ_RS01900
uniprot id: A8MBC9
names: Similarity
messages: Belongs to the malic enzymes family.

397948:CMAQ RS02830
gene id: 397948:CMAQ_RS02830
uniprot id: A8MC93
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

397948:CMAQ RS06465
gene id: 397948:CMAQ_RS06465
uniprot id: A8ME79
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS05675
gene id: 397948:CMAQ_RS05675
uniprot id: A8MDT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

397948:CMAQ RS06565
gene id: 397948:CMAQ_RS06565
uniprot id: A8M8N8
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS05885
gene id: 397948:CMAQ_RS05885
uniprot id: A8MDX2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

397948:CMAQ RS05315
gene id: 397948:CMAQ_RS05315
uniprot id: A8MDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Membrane

397948:CMAQ RS08845
gene id: 397948:CMAQ_RS08845
uniprot id: A8MAG5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

397948:CMAQ RS08575
gene id: 397948:CMAQ_RS08575
uniprot id: A8MAB5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS03460
gene id: 397948:CMAQ_RS03460
uniprot id: A8MCL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

397948:CMAQ RS00750
gene id: 397948:CMAQ_RS00750
uniprot id: A8MA62
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

397948:CMAQ RS04095
gene id: 397948:CMAQ_RS04095
uniprot id: A8MCY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS03395
gene id: 397948:CMAQ_RS03395
uniprot id: A8MCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

397948:CMAQ RS03400
gene id: 397948:CMAQ_RS03400
uniprot id: A8MCK3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

397948:CMAQ RS06410
gene id: 397948:CMAQ_RS06410
uniprot id: A8ME68
names: Similarity
messages: Belongs to the pirin family.

397948:CMAQ RS06210
gene id: 397948:CMAQ_RS06210
uniprot id: A8ME30
names: Similarity
messages: Belongs to the CinA family.

397948:CMAQ RS04635
gene id: 397948:CMAQ_RS04635
uniprot id: A8MD84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

397948:CMAQ RS00900
gene id: 397948:CMAQ_RS00900
uniprot id: A8MA91
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
messages: Reaction proceeds via a syn dehydration.

397948:CMAQ RS02015
gene id: 397948:CMAQ_RS02015
uniprot id: A8MBF0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs.

397948:CMAQ RS06575
gene id: 397948:CMAQ_RS06575
uniprot id: A8M8P0
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS07210
gene id: 397948:CMAQ_RS07210
uniprot id: A8M909
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

397948:CMAQ RS02340
gene id: 397948:CMAQ_RS02340
uniprot id: A8MBW0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

397948:CMAQ RS09160
gene id: 397948:CMAQ_RS09160
uniprot id: A8MAX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

397948:CMAQ RS08170
gene id: 397948:CMAQ_RS08170
uniprot id: A8M9U2
names: Similarity
messages: Belongs to the MEMO1 family.

397948:CMAQ RS05310
gene id: 397948:CMAQ_RS05310
uniprot id: A8MDL2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

397948:CMAQ RS04185
gene id: 397948:CMAQ_RS04185
uniprot id: A8MCZ9
names: Similarity
messages: Belongs to the PrpD family.

397948:CMAQ RS02230
gene id: 397948:CMAQ_RS02230
uniprot id: A8MBT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS06305
gene id: 397948:CMAQ_RS06305
uniprot id: A8ME48
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

397948:CMAQ RS04015
gene id: 397948:CMAQ_RS04015
uniprot id: A8MCW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS03475
gene id: 397948:CMAQ_RS03475
uniprot id: A8MCL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS02630
gene id: 397948:CMAQ_RS02630
uniprot id: A8MC55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

397948:CMAQ RS01725
gene id: 397948:CMAQ_RS01725
uniprot id: A8MB94
names: Similarity
messages: Belongs to the AOR/FOR family.

397948:CMAQ RS06680
gene id: 397948:CMAQ_RS06680
uniprot id: A8M8Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways.

397948:CMAQ RS10130
gene id: 397948:CMAQ_RS10130
uniprot id: A8MBZ9
names: Similarity
messages: Belongs to the PGI/PMI family.

397948:CMAQ RS04270
gene id: 397948:CMAQ_RS04270
uniprot id: A8MD16
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

397948:CMAQ RS04435
gene id: 397948:CMAQ_RS04435
uniprot id: A8MD49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

397948:CMAQ RS03040
gene id: 397948:CMAQ_RS03040
uniprot id: A8MCD3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

397948:CMAQ RS09185
gene id: 397948:CMAQ_RS09185
uniprot id: A8MAY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

397948:CMAQ RS04715
gene id: 397948:CMAQ_RS04715
uniprot id: A8MDA0
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

397948:CMAQ RS10405
gene id: 397948:CMAQ_RS10405
uniprot id: A8MDT4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

397948:CMAQ RS01585
gene id: 397948:CMAQ_RS01585
uniprot id: A8MB67
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

397948:CMAQ RS05150
gene id: 397948:CMAQ_RS05150
uniprot id: A8MDI3
names: Similarity
messages: Belongs to the UPF0179 family.

397948:CMAQ RS05060
gene id: 397948:CMAQ_RS05060
uniprot id: A8MDG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

397948:CMAQ RS03835
gene id: 397948:CMAQ_RS03835
uniprot id: A8MCT2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

397948:CMAQ RS04115
gene id: 397948:CMAQ_RS04115
uniprot id: A8MCY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS05815
gene id: 397948:CMAQ_RS05815
uniprot id: A8MDV8
names: Similarity
messages: Belongs to the AOR/FOR family.

397948:CMAQ RS08475
gene id: 397948:CMAQ_RS08475
uniprot id: A8MA01
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

397948:CMAQ RS03920
gene id: 397948:CMAQ_RS03920
uniprot id: A8MCU7
names: Similarity
messages: Belongs to the SfsA family.

397948:CMAQ RS04105
gene id: 397948:CMAQ_RS04105
uniprot id: A8MCY3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

397948:CMAQ RS02385
gene id: 397948:CMAQ_RS02385
uniprot id: A8MBW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

397948:CMAQ RS03915
gene id: 397948:CMAQ_RS03915
uniprot id: A8MCU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

397948:CMAQ RS09430
gene id: 397948:CMAQ_RS09430
uniprot id: A8MB20
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

397948:CMAQ RS00700
gene id: 397948:CMAQ_RS00700
uniprot id: A8MA52
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

397948:CMAQ RS03240
gene id: 397948:CMAQ_RS03240
uniprot id: A8MCH1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

397948:CMAQ RS06175
gene id: 397948:CMAQ_RS06175
uniprot id: A8ME23
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

397948:CMAQ RS08880
gene id: 397948:CMAQ_RS08880
uniprot id: A8MAH2
names: Similarity
messages: Belongs to the glutaredoxin family.

397948:CMAQ RS07270
gene id: 397948:CMAQ_RS07270
uniprot id: A8M919
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

397948:CMAQ RS04010
gene id: 397948:CMAQ_RS04010
uniprot id: A8MCW4
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

397948:CMAQ RS00630
gene id: 397948:CMAQ_RS00630
uniprot id: A8MA42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

397948:CMAQ RS10305
gene id: 397948:CMAQ_RS10305
uniprot id: A8MC33
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

397948:CMAQ RS04905
gene id: 397948:CMAQ_RS04905
uniprot id: A8MDD6
names: Similarity
messages: Belongs to the HypE family.

397948:CMAQ RS06985
gene id: 397948:CMAQ_RS06985
uniprot id: A8M8W7
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

397948:CMAQ RS09740
gene id: 397948:CMAQ_RS09740
uniprot id: A8MBH6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

397948:CMAQ RS06590
gene id: 397948:CMAQ_RS06590
uniprot id: A8M8P2
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

397948:CMAQ RS07925
gene id: 397948:CMAQ_RS07925
uniprot id: A8M9E5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS09245
gene id: 397948:CMAQ_RS09245
uniprot id: A8MAZ1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

397948:CMAQ RS00960
gene id: 397948:CMAQ_RS00960
uniprot id: A8MAA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

397948:CMAQ RS03225
gene id: 397948:CMAQ_RS03225
uniprot id: A8MCG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

397948:CMAQ RS05115
gene id: 397948:CMAQ_RS05115
uniprot id: A8MDH6
names: Similarity
messages: Belongs to the isopentenyl phosphate kinase family.

397948:CMAQ RS05405
gene id: 397948:CMAQ_RS05405
uniprot id: A8MDN0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

397948:CMAQ RS00125
gene id: 397948:CMAQ_RS00125
uniprot id: A8M9J7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS07255
gene id: 397948:CMAQ_RS07255
uniprot id: A8M916
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

397948:CMAQ RS04070
gene id: 397948:CMAQ_RS04070
uniprot id: A8MCX6
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

397948:CMAQ RS08455
gene id: 397948:CMAQ_RS08455
uniprot id: A8M9Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

397948:CMAQ RS08315
gene id: 397948:CMAQ_RS08315
uniprot id: A8M9W8
names: Similarity
messages: Belongs to the class-I fumarase family.

397948:CMAQ RS09140
gene id: 397948:CMAQ_RS09140
uniprot id: A8MAX2
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS00855
gene id: 397948:CMAQ_RS00855
uniprot id: A8MA82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

397948:CMAQ RS08815
gene id: 397948:CMAQ_RS08815
uniprot id: A8MAG0
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.

397948:CMAQ RS04870
gene id: 397948:CMAQ_RS04870
uniprot id: A8MDD0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

397948:CMAQ RS03685
gene id: 397948:CMAQ_RS03685
uniprot id: A8MCQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

397948:CMAQ RS02025
gene id: 397948:CMAQ_RS02025
uniprot id: A8MBP9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

397948:CMAQ RS02760
gene id: 397948:CMAQ_RS02760
uniprot id: A8MC80
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

397948:CMAQ RS00865
gene id: 397948:CMAQ_RS00865
uniprot id: A8MA84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

397948:CMAQ RS09200
gene id: 397948:CMAQ_RS09200
uniprot id: A8MAY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

397948:CMAQ RS02635
gene id: 397948:CMAQ_RS02635
uniprot id: A8MC56
names: Similarity
messages: In the N-terminal section; belongs to the DHNA family.

397948:CMAQ RS03605
gene id: 397948:CMAQ_RS03605
uniprot id: A8MCP0
names: Similarity
messages: Belongs to the AOR/FOR family.

397948:CMAQ RS04145
gene id: 397948:CMAQ_RS04145
uniprot id: A8MCZ1
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS06725
gene id: 397948:CMAQ_RS06725
uniprot id: A8M8R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

397948:CMAQ RS01850
gene id: 397948:CMAQ_RS01850
uniprot id: A8MBB9
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS05195
gene id: 397948:CMAQ_RS05195
uniprot id: A8MDJ2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

397948:CMAQ RS02175
gene id: 397948:CMAQ_RS02175
uniprot id: A8MBS7
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS05465
gene id: 397948:CMAQ_RS05465
uniprot id: A8MDP1
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

397948:CMAQ RS01945
gene id: 397948:CMAQ_RS01945
uniprot id: A8MBD7
names: Subcellular Location Annotation
messages: Nucleus

397948:CMAQ RS10080
gene id: 397948:CMAQ_RS10080
uniprot id: A8MBP1
names: Similarity
messages: Belongs to the glutaredoxin family.

397948:CMAQ RS06195
gene id: 397948:CMAQ_RS06195
uniprot id: A8ME27
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.

397948:CMAQ RS02655
gene id: 397948:CMAQ_RS02655
uniprot id: A8MC60
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homomer.

397948:CMAQ RS08490
gene id: 397948:CMAQ_RS08490
uniprot id: A8MA04
names: Similarity
messages: Belongs to the peptidase M24B family.

397948:CMAQ RS04155
gene id: 397948:CMAQ_RS04155
uniprot id: A8MCZ3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

397948:CMAQ RS09650
gene id: 397948:CMAQ_RS09650
uniprot id: A8MBF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

397948:CMAQ RS10245
gene id: 397948:CMAQ_RS10245
uniprot id: A8MC22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

397948:CMAQ RS04445
gene id: 397948:CMAQ_RS04445
uniprot id: A8MD51
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

397948:CMAQ RS05895
gene id: 397948:CMAQ_RS05895
uniprot id: A8MDX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

397948:CMAQ RS01765
gene id: 397948:CMAQ_RS01765
uniprot id: A8MBA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

397948:CMAQ RS03790
gene id: 397948:CMAQ_RS03790
uniprot id: A8MCS3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS09930
gene id: 397948:CMAQ_RS09930
uniprot id: A8MBL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

397948:CMAQ RS01865
gene id: 397948:CMAQ_RS01865
uniprot id: A8MBC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

397948:CMAQ RS04365
gene id: 397948:CMAQ_RS04365
uniprot id: A8MD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

397948:CMAQ RS04790
gene id: 397948:CMAQ_RS04790
uniprot id: A8MDB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

397948:CMAQ RS08495
gene id: 397948:CMAQ_RS08495
uniprot id: A8MA05
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

397948:CMAQ RS03775
gene id: 397948:CMAQ_RS03775
uniprot id: A8MCS0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

397948:CMAQ RS02425
gene id: 397948:CMAQ_RS02425
uniprot id: A8MBX7
names: Similarity
messages: Belongs to the ZPR1 family.

397948:CMAQ RS08695
gene id: 397948:CMAQ_RS08695
uniprot id: A8MAD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

397948:CMAQ RS02240
gene id: 397948:CMAQ_RS02240
uniprot id: A8MBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

397948:CMAQ RS01230
gene id: 397948:CMAQ_RS01230
uniprot id: A8MAQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

397948:CMAQ RS00975
gene id: 397948:CMAQ_RS00975
uniprot id: A8MAA6
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS02005
gene id: 397948:CMAQ_RS02005
uniprot id: A8MBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

397948:CMAQ RS03450
gene id: 397948:CMAQ_RS03450
uniprot id: A8MCL2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

397948:CMAQ RS06145
gene id: 397948:CMAQ_RS06145
uniprot id: A8ME18
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

397948:CMAQ RS06800
gene id: 397948:CMAQ_RS06800
uniprot id: A8M8T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS04580
gene id: 397948:CMAQ_RS04580
uniprot id: A8MD76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS04000
gene id: 397948:CMAQ_RS04000
uniprot id: A8MCW2
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

397948:CMAQ RS02825
gene id: 397948:CMAQ_RS02825
uniprot id: A8MC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

397948:CMAQ RS08670
gene id: 397948:CMAQ_RS08670
uniprot id: A8MAD4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

397948:CMAQ RS01700
gene id: 397948:CMAQ_RS01700
uniprot id: A8MB89
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

397948:CMAQ RS09750
gene id: 397948:CMAQ_RS09750
uniprot id: A8MBH8
names: Similarity
messages: Belongs to the UPF0215 family.

397948:CMAQ RS08950
gene id: 397948:CMAQ_RS08950
uniprot id: A8MAI6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

397948:CMAQ RS05720
gene id: 397948:CMAQ_RS05720
uniprot id: A8MDT9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

397948:CMAQ RS01570
gene id: 397948:CMAQ_RS01570
uniprot id: A8MB64
names: Similarity
messages: Belongs to the citrate synthase family.

397948:CMAQ RS01995
gene id: 397948:CMAQ_RS01995
uniprot id: A8MBE6
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

397948:CMAQ RS09590
gene id: 397948:CMAQ_RS09590
uniprot id: A8MB50
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

397948:CMAQ RS04740
gene id: 397948:CMAQ_RS04740
uniprot id: A8MDA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

397948:CMAQ RS07230
gene id: 397948:CMAQ_RS07230
uniprot id: A8M913
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

397948:CMAQ RS00210
gene id: 397948:CMAQ_RS00210
uniprot id: A8M9L4
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

397948:CMAQ RS08240
gene id: 397948:CMAQ_RS08240
uniprot id: A8M9V3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds to the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

397948:CMAQ RS07910
gene id: 397948:CMAQ_RS07910
uniprot id: A8M9E1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

397948:CMAQ RS06890
gene id: 397948:CMAQ_RS06890
uniprot id: A8M8U9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

397948:CMAQ RS02755
gene id: 397948:CMAQ_RS02755
uniprot id: A8MC79
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

397948:CMAQ RS09980
gene id: 397948:CMAQ_RS09980
uniprot id: A8MBM5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

397948:CMAQ RS06245
gene id: 397948:CMAQ_RS06245
uniprot id: A8ME36
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

397948:CMAQ RS08175
gene id: 397948:CMAQ_RS08175
uniprot id: A8M9U3
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS03440
gene id: 397948:CMAQ_RS03440
uniprot id: A8MCL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

397948:CMAQ RS05855
gene id: 397948:CMAQ_RS05855
uniprot id: A8MDW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS03640
gene id: 397948:CMAQ_RS03640
uniprot id: A8MCP6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS06285
gene id: 397948:CMAQ_RS06285
uniprot id: A8ME44
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

397948:CMAQ RS07200
gene id: 397948:CMAQ_RS07200
uniprot id: A8M907
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

397948:CMAQ RS05995
gene id: 397948:CMAQ_RS05995
uniprot id: A8MDZ1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Heterodimer composed of an alpha and a beta subunit.

397948:CMAQ RS05490
gene id: 397948:CMAQ_RS05490
uniprot id: A8MDP6
names: Similarity
messages: Belongs to the UPF0173 family.

397948:CMAQ RS02545
gene id: 397948:CMAQ_RS02545
uniprot id: A8MC37
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

397948:CMAQ RS03480
gene id: 397948:CMAQ_RS03480
uniprot id: A8MCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

397948:CMAQ RS03785
gene id: 397948:CMAQ_RS03785
uniprot id: A8MCS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

397948:CMAQ RS04530
gene id: 397948:CMAQ_RS04530
uniprot id: A8MD67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

397948:CMAQ RS03425
gene id: 397948:CMAQ_RS03425
uniprot id: A8MCK7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

397948:CMAQ RS03590
gene id: 397948:CMAQ_RS03590
uniprot id: A8MCN7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

397948:CMAQ RS00895
gene id: 397948:CMAQ_RS00895
uniprot id: A8MA90
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

397948:CMAQ RS07390
gene id: 397948:CMAQ_RS07390
uniprot id: A8M943
names: Similarity
messages: Belongs to the HepT RNase toxin family.

397948:CMAQ RS02260
gene id: 397948:CMAQ_RS02260
uniprot id: A8MBU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

397948:CMAQ RS10185
gene id: 397948:CMAQ_RS10185
uniprot id: A8MC10
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS09025
gene id: 397948:CMAQ_RS09025
uniprot id: A8MAK1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

397948:CMAQ RS09350
gene id: 397948:CMAQ_RS09350
uniprot id: A8MB06
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family.
messages: Heterodimer composed of an alpha and a beta subunit.

397948:CMAQ RS09490
gene id: 397948:CMAQ_RS09490
uniprot id: A8MB30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

397948:CMAQ RS00025
gene id: 397948:CMAQ_RS00025
uniprot id: A8M9H8
names: Similarity
messages: Belongs to the AOR/FOR family.

397948:CMAQ RS08300
gene id: 397948:CMAQ_RS08300
uniprot id: A8M9W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

397948:CMAQ RS08605
gene id: 397948:CMAQ_RS08605
uniprot id: A8MAC1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

397948:CMAQ RS03570
gene id: 397948:CMAQ_RS03570
uniprot id: A8MCN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

397948:CMAQ RS09920
gene id: 397948:CMAQ_RS09920
uniprot id: A8MBL3
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS10295
gene id: 397948:CMAQ_RS10295
uniprot id: A8MC31
names: Similarity
messages: Belongs to the UPF0201 family.

397948:CMAQ RS04695
gene id: 397948:CMAQ_RS04695
uniprot id: A8MD96
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

397948:CMAQ RS00800
gene id: 397948:CMAQ_RS00800
uniprot id: A8MA72
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
messages: Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

397948:CMAQ RS06300
gene id: 397948:CMAQ_RS06300
uniprot id: A8ME47
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

397948:CMAQ RS00345
gene id: 397948:CMAQ_RS00345
uniprot id: A8M9P0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

397948:CMAQ RS01430
gene id: 397948:CMAQ_RS01430
uniprot id: A8MAU0
names: Similarity
messages: Belongs to the peptidase M1 family.

397948:CMAQ RS09155
gene id: 397948:CMAQ_RS09155
uniprot id: A8MAX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

397948:CMAQ RS01735
gene id: 397948:CMAQ_RS01735
uniprot id: A8MB96
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

397948:CMAQ RS05740
gene id: 397948:CMAQ_RS05740
uniprot id: A8MDU3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

397948:CMAQ RS07140
gene id: 397948:CMAQ_RS07140
uniprot id: A8M8Z5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

397948:CMAQ RS01010
gene id: 397948:CMAQ_RS01010
uniprot id: A8MAB4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

397948:CMAQ RS09895
gene id: 397948:CMAQ_RS09895
uniprot id: A8MBK8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

397948:CMAQ RS02335
gene id: 397948:CMAQ_RS02335
uniprot id: A8MBV9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

397948:CMAQ RS08705
gene id: 397948:CMAQ_RS08705
uniprot id: A8MAE0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

397948:CMAQ RS00070
gene id: 397948:CMAQ_RS00070
uniprot id: A8M9I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS00075
gene id: 397948:CMAQ_RS00075
uniprot id: A8M9I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

397948:CMAQ RS07980
gene id: 397948:CMAQ_RS07980
uniprot id: A8M9F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

397948:CMAQ RS04860
gene id: 397948:CMAQ_RS04860
uniprot id: A8MDC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

397948:CMAQ RS00035
gene id: 397948:CMAQ_RS00035
uniprot id: A8M9I0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

397948:CMAQ RS00055
gene id: 397948:CMAQ_RS00055
uniprot id: A8M9I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

397948:CMAQ RS05760
gene id: 397948:CMAQ_RS05760
uniprot id: A8MDU7
names: Similarity
messages: Belongs to the acylphosphatase family.

397948:CMAQ RS01595
gene id: 397948:CMAQ_RS01595
uniprot id: A8MB69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

397948:CMAQ RS00140
gene id: 397948:CMAQ_RS00140
uniprot id: A8M9K0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

397948:CMAQ RS05980
gene id: 397948:CMAQ_RS05980
uniprot id: A8MDY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

397948:CMAQ RS04750
gene id: 397948:CMAQ_RS04750
uniprot id: A8MDA6
names: Similarity
messages: Belongs to the peptidase M1 family.

397948:CMAQ RS04760
gene id: 397948:CMAQ_RS04760
uniprot id: A8MDA8
names: Similarity
messages: Belongs to the UPF0147 family.

397948:CMAQ RS07215
gene id: 397948:CMAQ_RS07215
uniprot id: A8M910
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

397948:CMAQ RS00325
gene id: 397948:CMAQ_RS00325
uniprot id: A8M9N6
names: Similarity
messages: Belongs to the glutamate synthase family.

397948:CMAQ RS09565
gene id: 397948:CMAQ_RS09565
uniprot id: A8MB45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS06675
gene id: 397948:CMAQ_RS06675
uniprot id: A8M8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Cytoplasm
messages: Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis).

397948:CMAQ RS10160
gene id: 397948:CMAQ_RS10160
uniprot id: A8MC05
names: Similarity
messages: Belongs to the peptidase U62 family.

397948:CMAQ RS01335
gene id: 397948:CMAQ_RS01335
uniprot id: A8MAS2
names: Similarity
messages: Belongs to the AOR/FOR family.

397948:CMAQ RS10040
gene id: 397948:CMAQ_RS10040
uniprot id: A8MBN4
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

397948:CMAQ RS03850
gene id: 397948:CMAQ_RS03850
uniprot id: A8MCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

397948:CMAQ RS09310
gene id: 397948:CMAQ_RS09310
uniprot id: A8MAZ8
names: Similarity
messages: Belongs to the AOR/FOR family.

397948:CMAQ RS02495
gene id: 397948:CMAQ_RS02495
uniprot id: A8MBZ0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

397948:CMAQ RS06990
gene id: 397948:CMAQ_RS06990
uniprot id: A8M8W8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

397948:CMAQ RS07235
gene id: 397948:CMAQ_RS07235
uniprot id: A8M914
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

397948:CMAQ RS04045
gene id: 397948:CMAQ_RS04045
uniprot id: A8MCX1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

397948:CMAQ RS07890
gene id: 397948:CMAQ_RS07890
uniprot id: A8M9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

397948:CMAQ RS01095
gene id: 397948:CMAQ_RS01095
uniprot id: A8MAM7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

397948:CMAQ RS05360
gene id: 397948:CMAQ_RS05360
uniprot id: A8MDM2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

397948:CMAQ RS09475
gene id: 397948:CMAQ_RS09475
uniprot id: A8MB28
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

397948:CMAQ RS07580
gene id: 397948:CMAQ_RS07580
uniprot id: A8M978
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

397948:CMAQ RS03085
gene id: 397948:CMAQ_RS03085
uniprot id: A8MCE2
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

397948:CMAQ RS10090
gene id: 397948:CMAQ_RS10090
uniprot id: A8MBP3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS07130
gene id: 397948:CMAQ_RS07130
uniprot id: A8M8Z3
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

397948:CMAQ RS05775
gene id: 397948:CMAQ_RS05775
uniprot id: A8MDV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Involved in DNA damage repair.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS03185
gene id: 397948:CMAQ_RS03185
uniprot id: A8MCG1
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

397948:CMAQ RS01630
gene id: 397948:CMAQ_RS01630
uniprot id: A8MB76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

397948:CMAQ RS08185
gene id: 397948:CMAQ_RS08185
uniprot id: A8M9U4
names: Similarity
messages: Belongs to the UPF0045 family.

397948:CMAQ RS08380
gene id: 397948:CMAQ_RS08380
uniprot id: A8M9Y2
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

397948:CMAQ RS10150
gene id: 397948:CMAQ_RS10150
uniprot id: A8MC03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homodimer.

397948:CMAQ RS05795
gene id: 397948:CMAQ_RS05795
uniprot id: A8MDV4
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

397948:CMAQ RS00540
gene id: 397948:CMAQ_RS00540
uniprot id: A8MA26
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

397948:CMAQ RS06620
gene id: 397948:CMAQ_RS06620
uniprot id: A8M8P7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

397948:CMAQ RS08595
gene id: 397948:CMAQ_RS08595
uniprot id: A8MAB9
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS08615
gene id: 397948:CMAQ_RS08615
uniprot id: A8MAC3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

397948:CMAQ RS02520
gene id: 397948:CMAQ_RS02520
uniprot id: A8MBZ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.
messages: The N-terminal domain is an archaea-specific tRNA-editing domain that hydrolyzes incorrectly charged L-seryl-tRNA(Thr). Catalysis of tRNA editing is performed by the charged tRNA itself.

397948:CMAQ RS03830
gene id: 397948:CMAQ_RS03830
uniprot id: A8MCT1
names: Similarity
messages: Belongs to the UPF0282 family.

397948:CMAQ RS03535
gene id: 397948:CMAQ_RS03535
uniprot id: A8MCM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS05330
gene id: 397948:CMAQ_RS05330
uniprot id: A8MDL6
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

397948:CMAQ RS09555
gene id: 397948:CMAQ_RS09555
uniprot id: A8MB43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

397948:CMAQ RS04140
gene id: 397948:CMAQ_RS04140
uniprot id: A8MCZ0
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

397948:CMAQ RS02660
gene id: 397948:CMAQ_RS02660
uniprot id: A8MC62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

397948:CMAQ RS09355
gene id: 397948:CMAQ_RS09355
uniprot id: A8MB07
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

397948:CMAQ RS08790
gene id: 397948:CMAQ_RS08790
uniprot id: A8MAF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

397948:CMAQ RS08470
gene id: 397948:CMAQ_RS08470
uniprot id: A8MA00
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS06480
gene id: 397948:CMAQ_RS06480
uniprot id: A8ME82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

397948:CMAQ RS07055
gene id: 397948:CMAQ_RS07055
uniprot id: A8M8X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

397948:CMAQ RS00205
gene id: 397948:CMAQ_RS00205
uniprot id: A8M9L3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).

397948:CMAQ RS10235
gene id: 397948:CMAQ_RS10235
uniprot id: A8MC20
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

397948:CMAQ RS07205
gene id: 397948:CMAQ_RS07205
uniprot id: A8M908
names: Similarity
messages: Belongs to the HisA/HisF family.

397948:CMAQ RS06005
gene id: 397948:CMAQ_RS06005
uniprot id: A8MDZ3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

397948:CMAQ RS10125
gene id: 397948:CMAQ_RS10125
uniprot id: A8MBZ8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

397948:CMAQ RS08120
gene id: 397948:CMAQ_RS08120
uniprot id: A8M9T2
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

397948:CMAQ RS05850
gene id: 397948:CMAQ_RS05850
uniprot id: A8MDW5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

397948:CMAQ RS00850
gene id: 397948:CMAQ_RS00850
uniprot id: A8MA81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.

397948:CMAQ RS05985
gene id: 397948:CMAQ_RS05985
uniprot id: A8MDY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

397948:CMAQ RS09515
gene id: 397948:CMAQ_RS09515
uniprot id: A8MB35
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

397948:CMAQ RS01240
gene id: 397948:CMAQ_RS01240
uniprot id: A8MAQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

397948:CMAQ RS08285
gene id: 397948:CMAQ_RS08285
uniprot id: A8M9W2
names: Similarity
messages: Belongs to the HerA family.

397948:CMAQ RS04945
gene id: 397948:CMAQ_RS04945
uniprot id: A8MDE4
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

397948:CMAQ RS04805
gene id: 397948:CMAQ_RS04805
uniprot id: A8MDB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

397948:CMAQ RS08755
gene id: 397948:CMAQ_RS08755
uniprot id: A8MAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

397948:CMAQ RS09865
gene id: 397948:CMAQ_RS09865
uniprot id: A8MBK2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

397948:CMAQ RS02565
gene id: 397948:CMAQ_RS02565
uniprot id: A8MC41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

397948:CMAQ RS00255
gene id: 397948:CMAQ_RS00255
uniprot id: A8M9M3
names: Similarity
messages: Belongs to the glutaredoxin family.

397948:CMAQ RS07820
gene id: 397948:CMAQ_RS07820
uniprot id: A8M9C5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

397948:CMAQ RS04570
gene id: 397948:CMAQ_RS04570
uniprot id: A8MD75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS06555
gene id: 397948:CMAQ_RS06555
uniprot id: A8ME99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

397948:CMAQ RS00955
gene id: 397948:CMAQ_RS00955
uniprot id: A8MAA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

397948:CMAQ RS04420
gene id: 397948:CMAQ_RS04420
uniprot id: A8MD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

397948:CMAQ RS05180
gene id: 397948:CMAQ_RS05180
uniprot id: A8MDI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

397948:CMAQ RS07285
gene id: 397948:CMAQ_RS07285
uniprot id: A8M922
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

397948:CMAQ RS00870
gene id: 397948:CMAQ_RS00870
uniprot id: A8MA85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

397948:CMAQ RS06895
gene id: 397948:CMAQ_RS06895
uniprot id: A8M8V0
names: Similarity
messages: Belongs to the glutaredoxin family.

397948:CMAQ RS06840
gene id: 397948:CMAQ_RS06840
uniprot id: A8M8T9
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

397948:CMAQ RS02940
gene id: 397948:CMAQ_RS02940
uniprot id: A8MCB3
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

397948:CMAQ RS01015
gene id: 397948:CMAQ_RS01015
uniprot id: A8MAL1
names: Similarity
messages: Belongs to the SDO1/SBDS family.

397948:CMAQ RS00350
gene id: 397948:CMAQ_RS00350
uniprot id: A8M9P1
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS00050
gene id: 397948:CMAQ_RS00050
uniprot id: A8M9I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

397948:CMAQ RS03255
gene id: 397948:CMAQ_RS03255
uniprot id: A8MCH3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

397948:CMAQ RS05510
gene id: 397948:CMAQ_RS05510
uniprot id: A8MDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

397948:CMAQ RS08465
gene id: 397948:CMAQ_RS08465
uniprot id: A8M9Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

397948:CMAQ RS05340
gene id: 397948:CMAQ_RS05340
uniprot id: A8MDL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

397948:CMAQ RS07295
gene id: 397948:CMAQ_RS07295
uniprot id: A8M924
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

397948:CMAQ RS10340
gene id: 397948:CMAQ_RS10340
uniprot id: A8MC42
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

397948:CMAQ RS07635
gene id: 397948:CMAQ_RS07635
uniprot id: A8M988
names: Cofactor
messages: Binds 1 copper ion per subunit.

397948:CMAQ RS01005
gene id: 397948:CMAQ_RS01005
uniprot id: A8MAB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

397948:CMAQ RS04345
gene id: 397948:CMAQ_RS04345
uniprot id: A8MD31
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS03375
gene id: 397948:CMAQ_RS03375
uniprot id: A8MCJ8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

397948:CMAQ RS01645
gene id: 397948:CMAQ_RS01645
uniprot id: A8MB79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

397948:CMAQ RS08560
gene id: 397948:CMAQ_RS08560
uniprot id: A8MA18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

397948:CMAQ RS09510
gene id: 397948:CMAQ_RS09510
uniprot id: A8MB34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

397948:CMAQ RS06090
gene id: 397948:CMAQ_RS06090
uniprot id: A8ME08
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

397948:CMAQ RS00575
gene id: 397948:CMAQ_RS00575
uniprot id: A8MA31
names: Similarity
messages: Belongs to the type IA topoisomerase family.

397948:CMAQ RS01340
gene id: 397948:CMAQ_RS01340
uniprot id: A8MAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

397948:CMAQ RS06695
gene id: 397948:CMAQ_RS06695
uniprot id: A8M8R2
names: Function
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
messages: Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD(+) and NADP(+) as electron acceptor. Is involved in the degradation of glucose through a non-phosphorylative variant of the Entner-Doudoroff pathway.

397948:CMAQ RS08275
gene id: 397948:CMAQ_RS08275
uniprot id: A8M9W0
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS00820
gene id: 397948:CMAQ_RS00820
uniprot id: A8MA75
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

397948:CMAQ RS09715
gene id: 397948:CMAQ_RS09715
uniprot id: A8MBH1
names: Similarity
messages: Belongs to the Nth/MutY family.

397948:CMAQ RS04595
gene id: 397948:CMAQ_RS04595
uniprot id: A8MD78
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

397948:CMAQ RS04700
gene id: 397948:CMAQ_RS04700
uniprot id: A8MD97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

397948:CMAQ RS08140
gene id: 397948:CMAQ_RS08140
uniprot id: A8M9T6
names: Similarity
messages: Belongs to the arginase family.

397948:CMAQ RS06665
gene id: 397948:CMAQ_RS06665
uniprot id: A8M8Q6
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

397948:CMAQ RS01580
gene id: 397948:CMAQ_RS01580
uniprot id: A8MB66
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

397948:CMAQ RS00240
gene id: 397948:CMAQ_RS00240
uniprot id: A8M9M0
names: Similarity
messages: Belongs to the HerA family.

397948:CMAQ RS08015
gene id: 397948:CMAQ_RS08015
uniprot id: A8M9G2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

397948:CMAQ RS01875
gene id: 397948:CMAQ_RS01875
uniprot id: A8MBC4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

397948:CMAQ RS01955
gene id: 397948:CMAQ_RS01955
uniprot id: A8MBD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS03985
gene id: 397948:CMAQ_RS03985
uniprot id: A8MCV9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

397948:CMAQ RS01345
gene id: 397948:CMAQ_RS01345
uniprot id: A8MAS4
names: Similarity
messages: Belongs to the glutaredoxin family.

397948:CMAQ RS08295
gene id: 397948:CMAQ_RS08295
uniprot id: A8M9W4
names: Similarity
messages: Belongs to the UPF0047 family.

397948:CMAQ RS04090
gene id: 397948:CMAQ_RS04090
uniprot id: A8MCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS01745
gene id: 397948:CMAQ_RS01745
uniprot id: A8MB98
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

397948:CMAQ RS02880
gene id: 397948:CMAQ_RS02880
uniprot id: A8MCA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

397948:CMAQ RS05755
gene id: 397948:CMAQ_RS05755
uniprot id: A8MDU6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

397948:CMAQ RS10315
gene id: 397948:CMAQ_RS10315
uniprot id: A8MA63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS03900
gene id: 397948:CMAQ_RS03900
uniprot id: A8MCU3
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS06375
gene id: 397948:CMAQ_RS06375
uniprot id: A8ME61
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

397948:CMAQ RS09925
gene id: 397948:CMAQ_RS09925
uniprot id: A8MBL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

397948:CMAQ RS09500
gene id: 397948:CMAQ_RS09500
uniprot id: A8MB32
names: Similarity
messages: Belongs to the AAA ATPase family.

397948:CMAQ RS04815
gene id: 397948:CMAQ_RS04815
uniprot id: A8MDB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

397948:CMAQ RS03270
gene id: 397948:CMAQ_RS03270
uniprot id: A8MCH6
names: Subcellular Location Annotation
messages: Cytoplasm

397948:CMAQ RS02380
gene id: 397948:CMAQ_RS02380
uniprot id: A8MBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

397948:CMAQ RS07220
gene id: 397948:CMAQ_RS07220
uniprot id: A8M911
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

397948:CMAQ RS03285
gene id: 397948:CMAQ_RS03285
uniprot id: A8MCH9
names: Similarity
messages: Belongs to the HerA family.

397948:CMAQ RS01050
gene id: 397948:CMAQ_RS01050
uniprot id: A8MAL8
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS00665
gene id: 397948:CMAQ_RS00665
uniprot id: A8MA48
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS06650
gene id: 397948:CMAQ_RS06650
uniprot id: A8M8Q3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

397948:CMAQ RS05335
gene id: 397948:CMAQ_RS05335
uniprot id: A8MDL7
names: Similarity
messages: Belongs to the TrpF family.

397948:CMAQ RS03660
gene id: 397948:CMAQ_RS03660
uniprot id: A8MCQ0
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

397948:CMAQ RS06415
gene id: 397948:CMAQ_RS06415
uniprot id: A8ME69
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

397948:CMAQ RS04235
gene id: 397948:CMAQ_RS04235
uniprot id: A8MD09
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.

397948:CMAQ RS06275
gene id: 397948:CMAQ_RS06275
uniprot id: A8ME42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

397948:CMAQ RS07100
gene id: 397948:CMAQ_RS07100
uniprot id: A8M8Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

397948:CMAQ RS07110
gene id: 397948:CMAQ_RS07110
uniprot id: A8M8Y9
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

397948:CMAQ RS09180
gene id: 397948:CMAQ_RS09180
uniprot id: A8MAY0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

397948:CMAQ RS01640
gene id: 397948:CMAQ_RS01640
uniprot id: A8MB78
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

397948:CMAQ RS04065
gene id: 397948:CMAQ_RS04065
uniprot id: A8MCX5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS04990
gene id: 397948:CMAQ_RS04990
uniprot id: A8MDF3
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS03320
gene id: 397948:CMAQ_RS03320
uniprot id: A8MCI6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

397948:CMAQ RS09600
gene id: 397948:CMAQ_RS09600
uniprot id: A8MB52
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

397948:CMAQ RS02550
gene id: 397948:CMAQ_RS02550
uniprot id: A8MC38
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

397948:CMAQ RS09190
gene id: 397948:CMAQ_RS09190
uniprot id: A8MAY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

397948:CMAQ RS10180
gene id: 397948:CMAQ_RS10180
uniprot id: A8MC09
names: Similarity
messages: Belongs to the acylphosphatase family.

397948:CMAQ RS03880
gene id: 397948:CMAQ_RS03880
uniprot id: A8MCU0
names: Similarity
messages: Belongs to the SUI1 family.

397948:CMAQ RS09530
gene id: 397948:CMAQ_RS09530
uniprot id: A8MB38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

397948:CMAQ RS06720
gene id: 397948:CMAQ_RS06720
uniprot id: A8M8R7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

397948:CMAQ RS02600
gene id: 397948:CMAQ_RS02600
uniprot id: A8MC48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

397948:CMAQ RS08655
gene id: 397948:CMAQ_RS08655
uniprot id: A8MAD1
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS05395
gene id: 397948:CMAQ_RS05395
uniprot id: A8MDM8
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS08080
gene id: 397948:CMAQ_RS08080
uniprot id: A8M9S4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

397948:CMAQ RS04615
gene id: 397948:CMAQ_RS04615
uniprot id: A8MD82
names: Similarity
messages: Belongs to the RuvB family.

397948:CMAQ RS03015
gene id: 397948:CMAQ_RS03015
uniprot id: A8MCC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.

397948:CMAQ RS02510
gene id: 397948:CMAQ_RS02510
uniprot id: A8MBZ3
names: Similarity
messages: Belongs to the UPF0145 family.

397948:CMAQ RS06795
gene id: 397948:CMAQ_RS06795
uniprot id: A8M8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

397948:CMAQ RS06020
gene id: 397948:CMAQ_RS06020
uniprot id: A8MDZ6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

397948:CMAQ RS01190
gene id: 397948:CMAQ_RS01190
uniprot id: A8MAP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS08460
gene id: 397948:CMAQ_RS08460
uniprot id: A8M9Z8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

397948:CMAQ RS03105
gene id: 397948:CMAQ_RS03105
uniprot id: A8MCE6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

397948:CMAQ RS00780
gene id: 397948:CMAQ_RS00780
uniprot id: A8MA68
names: Similarity
messages: Belongs to the Ahb/Nir family.

397948:CMAQ RS01115
gene id: 397948:CMAQ_RS01115
uniprot id: A8MAN0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

397948:CMAQ RS01040
gene id: 397948:CMAQ_RS01040
uniprot id: A8MAL6
names: Similarity
messages: Belongs to the PDCD5 family.

397948:CMAQ RS02585
gene id: 397948:CMAQ_RS02585
uniprot id: A8MC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS09405
gene id: 397948:CMAQ_RS09405
uniprot id: A8MB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

397948:CMAQ RS00875
gene id: 397948:CMAQ_RS00875
uniprot id: A8MA86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Binds two Mg(2+) per subunit.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.

397948:CMAQ RS08115
gene id: 397948:CMAQ_RS08115
uniprot id: A8M9T1
names: Similarity
messages: Belongs to the class-I fumarase family.

397948:CMAQ RS06290
gene id: 397948:CMAQ_RS06290
uniprot id: A8ME45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).

397948:CMAQ RS09040
gene id: 397948:CMAQ_RS09040
uniprot id: A8MAK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS04035
gene id: 397948:CMAQ_RS04035
uniprot id: A8MCW9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

397948:CMAQ RS03595
gene id: 397948:CMAQ_RS03595
uniprot id: A8MCN8
names: Similarity
messages: Belongs to the xylose isomerase family.

397948:CMAQ RS01870
gene id: 397948:CMAQ_RS01870
uniprot id: A8MBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

397948:CMAQ RS02345
gene id: 397948:CMAQ_RS02345
uniprot id: A8MBW1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

397948:CMAQ RS05520
gene id: 397948:CMAQ_RS05520
uniprot id: A8MDQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

397948:CMAQ RS01030
gene id: 397948:CMAQ_RS01030
uniprot id: A8MAL4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

397948:CMAQ RS06830
gene id: 397948:CMAQ_RS06830
uniprot id: A8M8T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

397948:CMAQ RS06255
gene id: 397948:CMAQ_RS06255
uniprot id: A8ME38
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

397948:CMAQ RS01625
gene id: 397948:CMAQ_RS01625
uniprot id: A8MB75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

397948:CMAQ RS09460
gene id: 397948:CMAQ_RS09460
uniprot id: A8MB25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

397948:CMAQ RS00910
gene id: 397948:CMAQ_RS00910
uniprot id: A8MA93
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS01305
gene id: 397948:CMAQ_RS01305
uniprot id: A8MAR7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.

397948:CMAQ RS04255
gene id: 397948:CMAQ_RS04255
uniprot id: A8MD13
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS09770
gene id: 397948:CMAQ_RS09770
uniprot id: A8MBI2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

397948:CMAQ RS06730
gene id: 397948:CMAQ_RS06730
uniprot id: A8M8R9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

397948:CMAQ RS07530
gene id: 397948:CMAQ_RS07530
uniprot id: A8M968
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS09105
gene id: 397948:CMAQ_RS09105
uniprot id: A8MAW5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

397948:CMAQ RS00725
gene id: 397948:CMAQ_RS00725
uniprot id: A8MA57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

397948:CMAQ RS05095
gene id: 397948:CMAQ_RS05095
uniprot id: A8MDH2
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

397948:CMAQ RS01055
gene id: 397948:CMAQ_RS01055
uniprot id: A8MAL9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

397948:CMAQ RS08100
gene id: 397948:CMAQ_RS08100
uniprot id: A8M9S8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

397948:CMAQ RS07935
gene id: 397948:CMAQ_RS07935
uniprot id: A8M9E7
names: Similarity
messages: Belongs to the arginase family.

397948:CMAQ RS03495
gene id: 397948:CMAQ_RS03495
uniprot id: A8MCM1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

397948:CMAQ RS06395
gene id: 397948:CMAQ_RS06395
uniprot id: A8ME65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

397948:CMAQ RS01620
gene id: 397948:CMAQ_RS01620
uniprot id: A8MB74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

397948:CMAQ RS05595
gene id: 397948:CMAQ_RS05595
uniprot id: A8MDR6
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS07740
gene id: 397948:CMAQ_RS07740
uniprot id: A8M9A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

397948:CMAQ RS02610
gene id: 397948:CMAQ_RS02610
uniprot id: A8MC51
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

397948:CMAQ RS01285
gene id: 397948:CMAQ_RS01285
uniprot id: A8MAR3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

397948:CMAQ RS07025
gene id: 397948:CMAQ_RS07025
uniprot id: A8M8X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

397948:CMAQ RS08780
gene id: 397948:CMAQ_RS08780
uniprot id: A8MAF4
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS08900
gene id: 397948:CMAQ_RS08900
uniprot id: A8MAH6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

397948:CMAQ RS09425
gene id: 397948:CMAQ_RS09425
uniprot id: A8MB19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

397948:CMAQ RS00980
gene id: 397948:CMAQ_RS00980
uniprot id: A8MAA7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

397948:CMAQ RS06870
gene id: 397948:CMAQ_RS06870
uniprot id: A8M8U5
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

397948:CMAQ RS05645
gene id: 397948:CMAQ_RS05645
uniprot id: A8MDS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

397948:CMAQ RS05100
gene id: 397948:CMAQ_RS05100
uniprot id: A8MDH3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS01465
gene id: 397948:CMAQ_RS01465
uniprot id: A8MAU6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

397948:CMAQ RS07145
gene id: 397948:CMAQ_RS07145
uniprot id: A8M8Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

397948:CMAQ RS08370
gene id: 397948:CMAQ_RS08370
uniprot id: A8M9Y0
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

397948:CMAQ RS01950
gene id: 397948:CMAQ_RS01950
uniprot id: A8MBD8
names: Similarity
messages: Belongs to the MCM family.

397948:CMAQ RS03150
gene id: 397948:CMAQ_RS03150
uniprot id: A8MCF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

397948:CMAQ RS08865
gene id: 397948:CMAQ_RS08865
uniprot id: A8MAG9
names: Similarity
messages: Belongs to the HerA family.

397948:CMAQ RS10060
gene id: 397948:CMAQ_RS10060
uniprot id: A8MBN7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

397948:CMAQ RS00415
gene id: 397948:CMAQ_RS00415
uniprot id: A8M9Q3
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

397948:CMAQ RS05460
gene id: 397948:CMAQ_RS05460
uniprot id: A8MDP0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

397948:CMAQ RS04110
gene id: 397948:CMAQ_RS04110
uniprot id: A8MCY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

397948:CMAQ RS06445
gene id: 397948:CMAQ_RS06445
uniprot id: A8ME75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

397948:CMAQ RS09580
gene id: 397948:CMAQ_RS09580
uniprot id: A8MB48
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

397948:CMAQ RS09145
gene id: 397948:CMAQ_RS09145
uniprot id: A8MAX3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

397948:CMAQ RS04600
gene id: 397948:CMAQ_RS04600
uniprot id: A8MD79
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

397948:CMAQ RS01035
gene id: 397948:CMAQ_RS01035
uniprot id: A8MAL5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

397948:CMAQ RS04765
gene id: 397948:CMAQ_RS04765
uniprot id: A8MDA9
names: Similarity
messages: Belongs to the NadC/ModD family.

397948:CMAQ RS08920
gene id: 397948:CMAQ_RS08920
uniprot id: A8MAI0
names: Similarity
messages: Belongs to the MoaB/Mog family.

397948:CMAQ RS08570
gene id: 397948:CMAQ_RS08570
uniprot id: A8MA20
names: Similarity
messages: Belongs to the peptidase S66 family.

397948:CMAQ RS06530
gene id: 397948:CMAQ_RS06530
uniprot id: A8ME93
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS00290
gene id: 397948:CMAQ_RS00290
uniprot id: A8M9M9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

397948:CMAQ RS00710
gene id: 397948:CMAQ_RS00710
uniprot id: A8MA54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

397948:CMAQ RS00475
gene id: 397948:CMAQ_RS00475
uniprot id: A8M9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

397948:CMAQ RS05350
gene id: 397948:CMAQ_RS05350
uniprot id: A8MDM0
names: Function
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

397948:CMAQ RS03580
gene id: 397948:CMAQ_RS03580
uniprot id: A8MCN5
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

397948:CMAQ RS10120
gene id: 397948:CMAQ_RS10120
uniprot id: A8MBZ7
names: Similarity
messages: Belongs to the UPF0111 family.

397948:CMAQ RS01555
gene id: 397948:CMAQ_RS01555
uniprot id: A8MB61
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS01075
gene id: 397948:CMAQ_RS01075
uniprot id: A8MAM3
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

397948:CMAQ RS09915
gene id: 397948:CMAQ_RS09915
uniprot id: A8MBL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

397948:CMAQ RS08105
gene id: 397948:CMAQ_RS08105
uniprot id: A8M9S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

397948:CMAQ RS02045
gene id: 397948:CMAQ_RS02045
uniprot id: A8MBQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

397948:CMAQ RS02430
gene id: 397948:CMAQ_RS02430
uniprot id: A8MBX8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

397948:CMAQ RS00095
gene id: 397948:CMAQ_RS00095
uniprot id: A8M9J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

397948:CMAQ RS02960
gene id: 397948:CMAQ_RS02960
uniprot id: A8MCB7
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

397948:CMAQ RS05265
gene id: 397948:CMAQ_RS05265
uniprot id: A8MDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS09560
gene id: 397948:CMAQ_RS09560
uniprot id: A8MB44
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

397948:CMAQ RS10635
gene id: 397948:CMAQ_RS10635
uniprot id: A8MB80
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

397948:CMAQ RS04560
gene id: 397948:CMAQ_RS04560
uniprot id: A8MD73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

397948:CMAQ RS08740
gene id: 397948:CMAQ_RS08740
uniprot id: A8MAE7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS03350
gene id: 397948:CMAQ_RS03350
uniprot id: A8MCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

397948:CMAQ RS00315
gene id: 397948:CMAQ_RS00315
uniprot id: A8M9N4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

397948:CMAQ RS07085
gene id: 397948:CMAQ_RS07085
uniprot id: A8M8Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

397948:CMAQ RS07870
gene id: 397948:CMAQ_RS07870
uniprot id: A8M9D3
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

397948:CMAQ RS01970
gene id: 397948:CMAQ_RS01970
uniprot id: A8MBE2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

397948:CMAQ RS06710
gene id: 397948:CMAQ_RS06710
uniprot id: A8M8R5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

397948:CMAQ RS04490
gene id: 397948:CMAQ_RS04490
uniprot id: A8MD59
names: Similarity
messages: Belongs to the peptidase C56 family.

397948:CMAQ RS06270
gene id: 397948:CMAQ_RS06270
uniprot id: A8ME41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

397948:CMAQ RS00085
gene id: 397948:CMAQ_RS00085
uniprot id: A8M9J0
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS06475
gene id: 397948:CMAQ_RS06475
uniprot id: A8ME81
names: Subcellular Location Annotation
messages: Cytoplasm

397948:CMAQ RS03530
gene id: 397948:CMAQ_RS03530
uniprot id: A8MCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

397948:CMAQ RS04800
gene id: 397948:CMAQ_RS04800
uniprot id: A8MDB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

397948:CMAQ RS02255
gene id: 397948:CMAQ_RS02255
uniprot id: A8MBU3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

397948:CMAQ RS08610
gene id: 397948:CMAQ_RS08610
uniprot id: A8MAC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
messages: Cytoplasm

397948:CMAQ RS03905
gene id: 397948:CMAQ_RS03905
uniprot id: A8MCU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS04890
gene id: 397948:CMAQ_RS04890
uniprot id: A8MDD4
names: Subcellular Location Annotation
messages: Cell membrane

397948:CMAQ RS05485
gene id: 397948:CMAQ_RS05485
uniprot id: A8MDP5
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

397948:CMAQ RS05250
gene id: 397948:CMAQ_RS05250
uniprot id: A8MDK2
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS09905
gene id: 397948:CMAQ_RS09905
uniprot id: A8MBL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

397948:CMAQ RS01600
gene id: 397948:CMAQ_RS01600
uniprot id: A8MB70
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

397948:CMAQ RS02305
gene id: 397948:CMAQ_RS02305
uniprot id: A8MBV3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.
messages: Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity.

397948:CMAQ RS02950
gene id: 397948:CMAQ_RS02950
uniprot id: A8MCB5
names: Similarity
messages: Belongs to the pyruvate kinase family.

397948:CMAQ RS00215
gene id: 397948:CMAQ_RS00215
uniprot id: A8M9L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

397948:CMAQ RS04925
gene id: 397948:CMAQ_RS04925
uniprot id: A8MDE0
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS03390
gene id: 397948:CMAQ_RS03390
uniprot id: A8MCK1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

397948:CMAQ RS08660
gene id: 397948:CMAQ_RS08660
uniprot id: A8MAD2
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS01740
gene id: 397948:CMAQ_RS01740
uniprot id: A8MB97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

397948:CMAQ RS02700
gene id: 397948:CMAQ_RS02700
uniprot id: A8MC69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Reduced FMN (FMNH(2)).

397948:CMAQ RS08960
gene id: 397948:CMAQ_RS08960
uniprot id: A8MAI8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

397948:CMAQ RS01415
gene id: 397948:CMAQ_RS01415
uniprot id: A8MAT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

397948:CMAQ RS02090
gene id: 397948:CMAQ_RS02090
uniprot id: A8MBR0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

397948:CMAQ RS04845
gene id: 397948:CMAQ_RS04845
uniprot id: A8MDC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

397948:CMAQ RS04785
gene id: 397948:CMAQ_RS04785
uniprot id: A8MDB3
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS02280
gene id: 397948:CMAQ_RS02280
uniprot id: A8MBU8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

397948:CMAQ RS02070
gene id: 397948:CMAQ_RS02070
uniprot id: A8MBQ7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

397948:CMAQ RS07680
gene id: 397948:CMAQ_RS07680
uniprot id: A8M997
names: Subcellular Location Annotation
messages: Membrane

397948:CMAQ RS07305
gene id: 397948:CMAQ_RS07305
uniprot id: A8M926
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS03950
gene id: 397948:CMAQ_RS03950
uniprot id: A8MCV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

397948:CMAQ RS02675
gene id: 397948:CMAQ_RS02675
uniprot id: A8MC64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

397948:CMAQ RS00830
gene id: 397948:CMAQ_RS00830
uniprot id: A8MA77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

397948:CMAQ RS01930
gene id: 397948:CMAQ_RS01930
uniprot id: A8MBD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal adenylate kinase family.
messages: Cytoplasm

397948:CMAQ RS09340
gene id: 397948:CMAQ_RS09340
uniprot id: A8MB04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS10205
gene id: 397948:CMAQ_RS10205
uniprot id: A8MC14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

397948:CMAQ RS02180
gene id: 397948:CMAQ_RS02180
uniprot id: A8MBS8
names: Similarity
messages: Belongs to the complex I subunit 3 family.

397948:CMAQ RS00320
gene id: 397948:CMAQ_RS00320
uniprot id: A8M9N5
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

397948:CMAQ RS02595
gene id: 397948:CMAQ_RS02595
uniprot id: A8MC47
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

397948:CMAQ RS04230
gene id: 397948:CMAQ_RS04230
uniprot id: A8MD08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.

397948:CMAQ RS09855
gene id: 397948:CMAQ_RS09855
uniprot id: A8MBK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 2 family.
messages: Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

397948:CMAQ RS01180
gene id: 397948:CMAQ_RS01180
uniprot id: A8MAP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

397948:CMAQ RS03405
gene id: 397948:CMAQ_RS03405
uniprot id: A8MCK4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

397948:CMAQ RS08995
gene id: 397948:CMAQ_RS08995
uniprot id: A8MAJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.