395965:MSIL RS00310
gene id: 395965:MSIL_RS00310
uniprot id: B8EL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395965:MSIL RS06705
gene id: 395965:MSIL_RS06705
uniprot id: B8ER91
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS15355
gene id: 395965:MSIL_RS15355
uniprot id: B8EKP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

395965:MSIL RS07070
gene id: 395965:MSIL_RS07070
uniprot id: B8ESL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

395965:MSIL RS06200
gene id: 395965:MSIL_RS06200
uniprot id: B8EPG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

395965:MSIL RS14755
gene id: 395965:MSIL_RS14755
uniprot id: B8ETH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

395965:MSIL RS11650
gene id: 395965:MSIL_RS11650
uniprot id: B8EI92
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

395965:MSIL RS08295
gene id: 395965:MSIL_RS08295
uniprot id: B8EK35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

395965:MSIL RS06270
gene id: 395965:MSIL_RS06270
uniprot id: B8EPI4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395965:MSIL RS19300
gene id: 395965:MSIL_RS19300
uniprot id: B8EMK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

395965:MSIL RS11115
gene id: 395965:MSIL_RS11115
uniprot id: B8ESX5
names: Similarity
messages: Belongs to the ParB family.

395965:MSIL RS09345
gene id: 395965:MSIL_RS09345
uniprot id: B8ELZ7
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

395965:MSIL RS15200
gene id: 395965:MSIL_RS15200
uniprot id: B8EIS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

395965:MSIL RS14880
gene id: 395965:MSIL_RS14880
uniprot id: B8EIM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS14400
gene id: 395965:MSIL_RS14400
uniprot id: B8ETA7
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS07155
gene id: 395965:MSIL_RS07155
uniprot id: B8ESN0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395965:MSIL RS16460
gene id: 395965:MSIL_RS16460
uniprot id: B8EQC7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS13040
gene id: 395965:MSIL_RS13040
uniprot id: B8EM93
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

395965:MSIL RS04810
gene id: 395965:MSIL_RS04810
uniprot id: B8EJV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

395965:MSIL RS14240
gene id: 395965:MSIL_RS14240
uniprot id: B8ET76
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

395965:MSIL RS12505
gene id: 395965:MSIL_RS12505
uniprot id: B8EKK8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS13965
gene id: 395965:MSIL_RS13965
uniprot id: B8ERW7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

395965:MSIL RS00255
gene id: 395965:MSIL_RS00255
uniprot id: B8EL37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

395965:MSIL RS07600
gene id: 395965:MSIL_RS07600
uniprot id: B8ESV7
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS18060
gene id: 395965:MSIL_RS18060
uniprot id: B8EIV3
names: Similarity
messages: Belongs to the GST superfamily.

395965:MSIL RS04610
gene id: 395965:MSIL_RS04610
uniprot id: B8ESH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

395965:MSIL RS04625
gene id: 395965:MSIL_RS04625
uniprot id: B8ESH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

395965:MSIL RS00725
gene id: 395965:MSIL_RS00725
uniprot id: B8EMY8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

395965:MSIL RS04065
gene id: 395965:MSIL_RS04065
uniprot id: B8ER13
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

395965:MSIL RS02105
gene id: 395965:MSIL_RS02105
uniprot id: B8EQW8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

395965:MSIL RS18350
gene id: 395965:MSIL_RS18350
uniprot id: B8EJ05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS00870
gene id: 395965:MSIL_RS00870
uniprot id: B8EN13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

395965:MSIL RS15175
gene id: 395965:MSIL_RS15175
uniprot id: B8EIS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

395965:MSIL RS05825
gene id: 395965:MSIL_RS05825
uniprot id: B8ENG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

395965:MSIL RS13980
gene id: 395965:MSIL_RS13980
uniprot id: B8ERX0
names: Similarity
messages: Belongs to the peptidase A31 family.

395965:MSIL RS05685
gene id: 395965:MSIL_RS05685
uniprot id: B8ENE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

395965:MSIL RS01915
gene id: 395965:MSIL_RS01915
uniprot id: B8EQT1
names: Similarity
messages: Belongs to the manganese catalase family.

395965:MSIL RS01685
gene id: 395965:MSIL_RS01685
uniprot id: B8EQN6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

395965:MSIL RS11145
gene id: 395965:MSIL_RS11145
uniprot id: B8ESY2
names: Cofactor
messages: Binds 2 manganese ions per subunit.

395965:MSIL RS12925
gene id: 395965:MSIL_RS12925
uniprot id: B8EM70
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

395965:MSIL RS08555
gene id: 395965:MSIL_RS08555
uniprot id: B8EK87
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS16615
gene id: 395965:MSIL_RS16615
uniprot id: B8EQF9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

395965:MSIL RS11850
gene id: 395965:MSIL_RS11850
uniprot id: B8EID1
names: Similarity
messages: Belongs to the OmpW/AlkL family.

395965:MSIL RS08820
gene id: 395965:MSIL_RS08820
uniprot id: B8EKD8
names: Similarity
messages: Belongs to the type IB topoisomerase family.

395965:MSIL RS13715
gene id: 395965:MSIL_RS13715
uniprot id: B8ERR8
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS02970
gene id: 395965:MSIL_RS02970
uniprot id: B8ELG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

395965:MSIL RS08730
gene id: 395965:MSIL_RS08730
uniprot id: B8EKC1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

395965:MSIL RS08880
gene id: 395965:MSIL_RS08880
uniprot id: B8EKE9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

395965:MSIL RS12325
gene id: 395965:MSIL_RS12325
uniprot id: B8EKH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

395965:MSIL RS18575
gene id: 395965:MSIL_RS18575
uniprot id: B8EJ50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

395965:MSIL RS08870
gene id: 395965:MSIL_RS08870
uniprot id: B8EKE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

395965:MSIL RS09220
gene id: 395965:MSIL_RS09220
uniprot id: B8ELX2
names: Similarity
messages: Belongs to the EfeM/EfeO family.

395965:MSIL RS06065
gene id: 395965:MSIL_RS06065
uniprot id: B8EPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

395965:MSIL RS10455
gene id: 395965:MSIL_RS10455
uniprot id: B8EPY4
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

395965:MSIL RS08965
gene id: 395965:MSIL_RS08965
uniprot id: B8ELS5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

395965:MSIL RS01105
gene id: 395965:MSIL_RS01105
uniprot id: B8EN61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

395965:MSIL RS03685
gene id: 395965:MSIL_RS03685
uniprot id: B8EPA1
names: Similarity
messages: Belongs to the TlyA family.

395965:MSIL RS04475
gene id: 395965:MSIL_RS04475
uniprot id: B8ESE7
names: Similarity
messages: Belongs to the glutamate synthase family.

395965:MSIL RS14765
gene id: 395965:MSIL_RS14765
uniprot id: B8ETH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

395965:MSIL RS05490
gene id: 395965:MSIL_RS05490
uniprot id: B8ELP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

395965:MSIL RS00855
gene id: 395965:MSIL_RS00855
uniprot id: B8EN11
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

395965:MSIL RS19405
gene id: 395965:MSIL_RS19405
uniprot id: B8EMM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

395965:MSIL RS02020
gene id: 395965:MSIL_RS02020
uniprot id: B8EQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

395965:MSIL RS19635
gene id: 395965:MSIL_RS19635
uniprot id: B8EMS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

395965:MSIL RS00705
gene id: 395965:MSIL_RS00705
uniprot id: B8EMY4
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

395965:MSIL RS06805
gene id: 395965:MSIL_RS06805
uniprot id: B8ERB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

395965:MSIL RS08030
gene id: 395965:MSIL_RS08030
uniprot id: B8EI44
names: Subcellular Location Annotation
messages: Cell inner membrane

395965:MSIL RS13090
gene id: 395965:MSIL_RS13090
uniprot id: B8EMA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS08325
gene id: 395965:MSIL_RS08325
uniprot id: B8EK41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

395965:MSIL RS01440
gene id: 395965:MSIL_RS01440
uniprot id: B8EP21
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS12930
gene id: 395965:MSIL_RS12930
uniprot id: B8EM71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

395965:MSIL RS02035
gene id: 395965:MSIL_RS02035
uniprot id: B8EQV4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

395965:MSIL RS19570
gene id: 395965:MSIL_RS19570
uniprot id: B8EMQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

395965:MSIL RS11060
gene id: 395965:MSIL_RS11060
uniprot id: B8EN20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

395965:MSIL RS07660
gene id: 395965:MSIL_RS07660
uniprot id: B8ESW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS17000
gene id: 395965:MSIL_RS17000
uniprot id: B8ES31
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS16565
gene id: 395965:MSIL_RS16565
uniprot id: B8EQE8
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

395965:MSIL RS12870
gene id: 395965:MSIL_RS12870
uniprot id: B8EM58
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

395965:MSIL RS15210
gene id: 395965:MSIL_RS15210
uniprot id: B8EIS9
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS13805
gene id: 395965:MSIL_RS13805
uniprot id: B8ERT6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

395965:MSIL RS00105
gene id: 395965:MSIL_RS00105
uniprot id: B8EL08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

395965:MSIL RS12240
gene id: 395965:MSIL_RS12240
uniprot id: B8EKF6
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

395965:MSIL RS17435
gene id: 395965:MSIL_RS17435
uniprot id: B8ESB0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395965:MSIL RS09785
gene id: 395965:MSIL_RS09785
uniprot id: B8ENS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

395965:MSIL RS00575
gene id: 395965:MSIL_RS00575
uniprot id: B8EL97
names: Cofactor
messages: Binds 2 manganese ions per subunit.

395965:MSIL RS03530
gene id: 395965:MSIL_RS03530
uniprot id: B8EP74
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

395965:MSIL RS20350
gene id: 395965:MSIL_RS20350
uniprot id: B8EQC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS10765
gene id: 395965:MSIL_RS10765
uniprot id: B8ERJ5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

395965:MSIL RS19130
gene id: 395965:MSIL_RS19130
uniprot id: B8EJF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

395965:MSIL RS18475
gene id: 395965:MSIL_RS18475
uniprot id: B8EJ30
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

395965:MSIL RS09540
gene id: 395965:MSIL_RS09540
uniprot id: B8ENN1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

395965:MSIL RS02715
gene id: 395965:MSIL_RS02715
uniprot id: B8ELB7
names: Function
messages: Acts on leucine, isoleucine and valine.

395965:MSIL RS00020
gene id: 395965:MSIL_RS00020
uniprot id: B8EJI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

395965:MSIL RS04365
gene id: 395965:MSIL_RS04365
uniprot id: B8ESC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

395965:MSIL RS18025
gene id: 395965:MSIL_RS18025
uniprot id: B8ETT6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

395965:MSIL RS18450
gene id: 395965:MSIL_RS18450
uniprot id: B8EJ25
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-102 inactivates the nitrogenase reductase and regulates nitrogenase activity.

395965:MSIL RS05500
gene id: 395965:MSIL_RS05500
uniprot id: B8ELP2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

395965:MSIL RS07970
gene id: 395965:MSIL_RS07970
uniprot id: B8EI32
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

395965:MSIL RS17530
gene id: 395965:MSIL_RS17530
uniprot id: B8ETJ0
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS16370
gene id: 395965:MSIL_RS16370
uniprot id: B8EMJ4
names: Similarity
messages: Belongs to the pirin family.

395965:MSIL RS11515
gene id: 395965:MSIL_RS11515
uniprot id: B8ET52
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS13960
gene id: 395965:MSIL_RS13960
uniprot id: B8ERW6
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

395965:MSIL RS18000
gene id: 395965:MSIL_RS18000
uniprot id: B8ETT1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

395965:MSIL RS02665
gene id: 395965:MSIL_RS02665
uniprot id: B8EJU2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

395965:MSIL RS04860
gene id: 395965:MSIL_RS04860
uniprot id: B8EJW3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

395965:MSIL RS05520
gene id: 395965:MSIL_RS05520
uniprot id: B8ELP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

395965:MSIL RS08835
gene id: 395965:MSIL_RS08835
uniprot id: B8EKE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

395965:MSIL RS02590
gene id: 395965:MSIL_RS02590
uniprot id: B8EJS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395965:MSIL RS02605
gene id: 395965:MSIL_RS02605
uniprot id: B8EJT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

395965:MSIL RS01070
gene id: 395965:MSIL_RS01070
uniprot id: B8EN54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

395965:MSIL RS06100
gene id: 395965:MSIL_RS06100
uniprot id: B8EPE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

395965:MSIL RS03130
gene id: 395965:MSIL_RS03130
uniprot id: B8EN74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395965:MSIL RS03255
gene id: 395965:MSIL_RS03255
uniprot id: B8EN97
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

395965:MSIL RS08165
gene id: 395965:MSIL_RS08165
uniprot id: B8EI70
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

395965:MSIL RS18435
gene id: 395965:MSIL_RS18435
uniprot id: B8EJ22
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

395965:MSIL RS13570
gene id: 395965:MSIL_RS13570
uniprot id: B8EQ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

395965:MSIL RS16000
gene id: 395965:MSIL_RS16000
uniprot id: B8EMC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

395965:MSIL RS06780
gene id: 395965:MSIL_RS06780
uniprot id: B8ERA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395965:MSIL RS08005
gene id: 395965:MSIL_RS08005
uniprot id: B8EI39
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

395965:MSIL RS19475
gene id: 395965:MSIL_RS19475
uniprot id: B8EMN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS18380
gene id: 395965:MSIL_RS18380
uniprot id: B8EJ11
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

395965:MSIL RS02860
gene id: 395965:MSIL_RS02860
uniprot id: B8ELE5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

395965:MSIL RS18370
gene id: 395965:MSIL_RS18370
uniprot id: B8EJ09
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

395965:MSIL RS08950
gene id: 395965:MSIL_RS08950
uniprot id: B8ELS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS07455
gene id: 395965:MSIL_RS07455
uniprot id: B8EST3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395965:MSIL RS06130
gene id: 395965:MSIL_RS06130
uniprot id: B8EPF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS09195
gene id: 395965:MSIL_RS09195
uniprot id: B8ELW7
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

395965:MSIL RS14710
gene id: 395965:MSIL_RS14710
uniprot id: B8ETG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS12910
gene id: 395965:MSIL_RS12910
uniprot id: B8EM67
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS12715
gene id: 395965:MSIL_RS12715
uniprot id: B8EM31
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS11395
gene id: 395965:MSIL_RS11395
uniprot id: B8ET28
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

395965:MSIL RS15640
gene id: 395965:MSIL_RS15640
uniprot id: B8EKV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

395965:MSIL RS16085
gene id: 395965:MSIL_RS16085
uniprot id: B8EMD8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

395965:MSIL RS18570
gene id: 395965:MSIL_RS18570
uniprot id: B8EJ49
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

395965:MSIL RS05815
gene id: 395965:MSIL_RS05815
uniprot id: B8ENG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

395965:MSIL RS12935
gene id: 395965:MSIL_RS12935
uniprot id: B8EM72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

395965:MSIL RS04970
gene id: 395965:MSIL_RS04970
uniprot id: B8EJY4
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS04715
gene id: 395965:MSIL_RS04715
uniprot id: B8ESJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS09865
gene id: 395965:MSIL_RS09865
uniprot id: B8ENU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

395965:MSIL RS12640
gene id: 395965:MSIL_RS12640
uniprot id: B8EKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

395965:MSIL RS17645
gene id: 395965:MSIL_RS17645
uniprot id: B8ETL3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

395965:MSIL RS03440
gene id: 395965:MSIL_RS03440
uniprot id: B8EP59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

395965:MSIL RS05840
gene id: 395965:MSIL_RS05840
uniprot id: B8ENH1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

395965:MSIL RS03775
gene id: 395965:MSIL_RS03775
uniprot id: B8EPB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alphaproteobacteria porin family.
messages: Cell outer membrane
messages: Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.
messages: Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.

395965:MSIL RS00560
gene id: 395965:MSIL_RS00560
uniprot id: B8EL94
names: Similarity
messages: Belongs to the ketopantoate reductase family.

395965:MSIL RS17190
gene id: 395965:MSIL_RS17190
uniprot id: B8ES69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS08790
gene id: 395965:MSIL_RS08790
uniprot id: B8EKD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS05640
gene id: 395965:MSIL_RS05640
uniprot id: B8END3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

395965:MSIL RS10270
gene id: 395965:MSIL_RS10270
uniprot id: B8EPV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

395965:MSIL RS16705
gene id: 395965:MSIL_RS16705
uniprot id: B8EQH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

395965:MSIL RS15980
gene id: 395965:MSIL_RS15980
uniprot id: B8EMB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

395965:MSIL RS01455
gene id: 395965:MSIL_RS01455
uniprot id: B8EP24
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

395965:MSIL RS12860
gene id: 395965:MSIL_RS12860
uniprot id: B8EM56
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

395965:MSIL RS07150
gene id: 395965:MSIL_RS07150
uniprot id: B8ESM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS04765
gene id: 395965:MSIL_RS04765
uniprot id: B8ESK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

395965:MSIL RS05365
gene id: 395965:MSIL_RS05365
uniprot id: B8ELL4
names: Similarity
messages: Belongs to the RelE toxin family.

395965:MSIL RS03755
gene id: 395965:MSIL_RS03755
uniprot id: B8EPB4
names: Similarity
messages: Belongs to the cytochrome P450 family.

395965:MSIL RS09545
gene id: 395965:MSIL_RS09545
uniprot id: B8ENN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

395965:MSIL RS09805
gene id: 395965:MSIL_RS09805
uniprot id: B8ENS9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS01090
gene id: 395965:MSIL_RS01090
uniprot id: B8EN58
names: Similarity
messages: Belongs to the phosphohexose mutase family.

395965:MSIL RS11815
gene id: 395965:MSIL_RS11815
uniprot id: B8EIC4
names: Similarity
messages: Belongs to the fructosamine kinase family.

395965:MSIL RS00245
gene id: 395965:MSIL_RS00245
uniprot id: B8EL36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

395965:MSIL RS06800
gene id: 395965:MSIL_RS06800
uniprot id: B8ERB0
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS17755
gene id: 395965:MSIL_RS17755
uniprot id: B8ETN6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

395965:MSIL RS07440
gene id: 395965:MSIL_RS07440
uniprot id: B8EST0
names: Similarity
messages: Belongs to the universal stress protein A family.

395965:MSIL RS13950
gene id: 395965:MSIL_RS13950
uniprot id: B8ERW4
names: Similarity
messages: Belongs to the HypD family.

395965:MSIL RS06855
gene id: 395965:MSIL_RS06855
uniprot id: B8ERC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

395965:MSIL RS10160
gene id: 395965:MSIL_RS10160
uniprot id: B8EPS8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

395965:MSIL RS03590
gene id: 395965:MSIL_RS03590
uniprot id: B8EP85
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395965:MSIL RS09685
gene id: 395965:MSIL_RS09685
uniprot id: B8ENQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

395965:MSIL RS00145
gene id: 395965:MSIL_RS00145
uniprot id: B8EL16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

395965:MSIL RS05350
gene id: 395965:MSIL_RS05350
uniprot id: B8ELL1
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS05790
gene id: 395965:MSIL_RS05790
uniprot id: B8ENG1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

395965:MSIL RS06370
gene id: 395965:MSIL_RS06370
uniprot id: B8EPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

395965:MSIL RS14325
gene id: 395965:MSIL_RS14325
uniprot id: B8ET92
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell inner membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

395965:MSIL RS09585
gene id: 395965:MSIL_RS09585
uniprot id: B8ENP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

395965:MSIL RS03325
gene id: 395965:MSIL_RS03325
uniprot id: B8ENB1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

395965:MSIL RS00175
gene id: 395965:MSIL_RS00175
uniprot id: B8EL22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

395965:MSIL RS06440
gene id: 395965:MSIL_RS06440
uniprot id: B8EPL9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

395965:MSIL RS10770
gene id: 395965:MSIL_RS10770
uniprot id: B8ERJ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

395965:MSIL RS05050
gene id: 395965:MSIL_RS05050
uniprot id: B8EK00
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

395965:MSIL RS16465
gene id: 395965:MSIL_RS16465
uniprot id: B8EQC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

395965:MSIL RS14280
gene id: 395965:MSIL_RS14280
uniprot id: B8ET83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

395965:MSIL RS16700
gene id: 395965:MSIL_RS16700
uniprot id: B8EQH6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

395965:MSIL RS00180
gene id: 395965:MSIL_RS00180
uniprot id: B8EL23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

395965:MSIL RS18255
gene id: 395965:MSIL_RS18255
uniprot id: B8EIY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

395965:MSIL RS02410
gene id: 395965:MSIL_RS02410
uniprot id: B8EJP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methanol dehydrogenase subunit 2 family.
messages: Catalyzes the oxidation of primary alcohols including methanol.
messages: Heterotetramer composed of 2 alpha and 2 beta subunits.

395965:MSIL RS05335
gene id: 395965:MSIL_RS05335
uniprot id: B8ELK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS08150
gene id: 395965:MSIL_RS08150
uniprot id: B8EI67
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

395965:MSIL RS19535
gene id: 395965:MSIL_RS19535
uniprot id: B8EMQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

395965:MSIL RS12515
gene id: 395965:MSIL_RS12515
uniprot id: B8EKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS06715
gene id: 395965:MSIL_RS06715
uniprot id: B8ER93
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

395965:MSIL RS09135
gene id: 395965:MSIL_RS09135
uniprot id: B8ELV6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395965:MSIL RS18430
gene id: 395965:MSIL_RS18430
uniprot id: B8EJ21
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

395965:MSIL RS10495
gene id: 395965:MSIL_RS10495
uniprot id: B8EPZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components.

395965:MSIL RS06925
gene id: 395965:MSIL_RS06925
uniprot id: B8ERD4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

395965:MSIL RS07740
gene id: 395965:MSIL_RS07740
uniprot id: B8EHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS14930
gene id: 395965:MSIL_RS14930
uniprot id: B8EIN3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

395965:MSIL RS03965
gene id: 395965:MSIL_RS03965
uniprot id: B8EQZ5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS01400
gene id: 395965:MSIL_RS01400
uniprot id: B8EP13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

395965:MSIL RS05005
gene id: 395965:MSIL_RS05005
uniprot id: B8EJZ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS14815
gene id: 395965:MSIL_RS14815
uniprot id: B8EIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

395965:MSIL RS01380
gene id: 395965:MSIL_RS01380
uniprot id: B8EP09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

395965:MSIL RS08215
gene id: 395965:MSIL_RS08215
uniprot id: B8EI78
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

395965:MSIL RS10610
gene id: 395965:MSIL_RS10610
uniprot id: B8ERG4
names: Similarity
messages: Belongs to the UPF0758 family.

395965:MSIL RS08575
gene id: 395965:MSIL_RS08575
uniprot id: B8EK90
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

395965:MSIL RS01175
gene id: 395965:MSIL_RS01175
uniprot id: B8ENX1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

395965:MSIL RS03225
gene id: 395965:MSIL_RS03225
uniprot id: B8EN92
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

395965:MSIL RS08745
gene id: 395965:MSIL_RS08745
uniprot id: B8EKC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

395965:MSIL RS02110
gene id: 395965:MSIL_RS02110
uniprot id: B8EQW9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

395965:MSIL RS05090
gene id: 395965:MSIL_RS05090
uniprot id: B8EK08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

395965:MSIL RS13810
gene id: 395965:MSIL_RS13810
uniprot id: B8ERT7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

395965:MSIL RS13830
gene id: 395965:MSIL_RS13830
uniprot id: B8ERU1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395965:MSIL RS10415
gene id: 395965:MSIL_RS10415
uniprot id: B8EPX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
messages: Homodimer. Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB.

395965:MSIL RS10485
gene id: 395965:MSIL_RS10485
uniprot id: B8EPZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

395965:MSIL RS02585
gene id: 395965:MSIL_RS02585
uniprot id: B8EJS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

395965:MSIL RS11725
gene id: 395965:MSIL_RS11725
uniprot id: B8EIA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

395965:MSIL RS02745
gene id: 395965:MSIL_RS02745
uniprot id: B8ELC3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

395965:MSIL RS00345
gene id: 395965:MSIL_RS00345
uniprot id: B8EL55
names: Similarity
messages: Belongs to the leucine-binding protein family.

395965:MSIL RS15125
gene id: 395965:MSIL_RS15125
uniprot id: B8EIR4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

395965:MSIL RS14585
gene id: 395965:MSIL_RS14585
uniprot id: B8ETE4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

395965:MSIL RS04820
gene id: 395965:MSIL_RS04820
uniprot id: B8EJV5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

395965:MSIL RS15245
gene id: 395965:MSIL_RS15245
uniprot id: B8EIT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

395965:MSIL RS18850
gene id: 395965:MSIL_RS18850
uniprot id: B8EJA2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

395965:MSIL RS08260
gene id: 395965:MSIL_RS08260
uniprot id: B8EI87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

395965:MSIL RS15015
gene id: 395965:MSIL_RS15015
uniprot id: B8EIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

395965:MSIL RS07350
gene id: 395965:MSIL_RS07350
uniprot id: B8ESR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

395965:MSIL RS04965
gene id: 395965:MSIL_RS04965
uniprot id: B8EJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

395965:MSIL RS15070
gene id: 395965:MSIL_RS15070
uniprot id: B8EIQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

395965:MSIL RS02565
gene id: 395965:MSIL_RS02565
uniprot id: B8EJS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

395965:MSIL RS03560
gene id: 395965:MSIL_RS03560
uniprot id: B8EP80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide deacetylase family.
messages: Cytoplasm
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

395965:MSIL RS06000
gene id: 395965:MSIL_RS06000
uniprot id: B8ENK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS16080
gene id: 395965:MSIL_RS16080
uniprot id: B8EMD7
names: Cofactor
messages: Can also use Mn(2+) ion.

395965:MSIL RS02150
gene id: 395965:MSIL_RS02150
uniprot id: B8EQX7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS04225
gene id: 395965:MSIL_RS04225
uniprot id: B8ER44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

395965:MSIL RS13205
gene id: 395965:MSIL_RS13205
uniprot id: B8EQ24
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

395965:MSIL RS02240
gene id: 395965:MSIL_RS02240
uniprot id: B8EJL2
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS06215
gene id: 395965:MSIL_RS06215
uniprot id: B8EPH2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

395965:MSIL RS03800
gene id: 395965:MSIL_RS03800
uniprot id: B8EPC0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

395965:MSIL RS14330
gene id: 395965:MSIL_RS14330
uniprot id: B8ET93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

395965:MSIL RS05930
gene id: 395965:MSIL_RS05930
uniprot id: B8ENI9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

395965:MSIL RS11890
gene id: 395965:MSIL_RS11890
uniprot id: B8EID9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

395965:MSIL RS06415
gene id: 395965:MSIL_RS06415
uniprot id: B8EPL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

395965:MSIL RS07010
gene id: 395965:MSIL_RS07010
uniprot id: B8ERF1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

395965:MSIL RS12680
gene id: 395965:MSIL_RS12680
uniprot id: B8EM24
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

395965:MSIL RS00190
gene id: 395965:MSIL_RS00190
uniprot id: B8EL25
names: Similarity
messages: Belongs to the MotB family.

395965:MSIL RS19055
gene id: 395965:MSIL_RS19055
uniprot id: B8EJE2
names: Similarity
messages: Belongs to the HupF/HypC family.

395965:MSIL RS12775
gene id: 395965:MSIL_RS12775
uniprot id: B8EM39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

395965:MSIL RS11445
gene id: 395965:MSIL_RS11445
uniprot id: B8ET38
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS09230
gene id: 395965:MSIL_RS09230
uniprot id: B8ELX4
names: Similarity
messages: Belongs to the EfeM/EfeO family.

395965:MSIL RS02660
gene id: 395965:MSIL_RS02660
uniprot id: B8EJU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

395965:MSIL RS18920
gene id: 395965:MSIL_RS18920
uniprot id: B8EJB5
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

395965:MSIL RS12945
gene id: 395965:MSIL_RS12945
uniprot id: B8EM74
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

395965:MSIL RS12520
gene id: 395965:MSIL_RS12520
uniprot id: B8EKL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS12375
gene id: 395965:MSIL_RS12375
uniprot id: B8EKI3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395965:MSIL RS08695
gene id: 395965:MSIL_RS08695
uniprot id: B8EKB4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

395965:MSIL RS05795
gene id: 395965:MSIL_RS05795
uniprot id: B8ENG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

395965:MSIL RS16970
gene id: 395965:MSIL_RS16970
uniprot id: B8ES25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

395965:MSIL RS02005
gene id: 395965:MSIL_RS02005
uniprot id: B8EQU8
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS06155
gene id: 395965:MSIL_RS06155
uniprot id: B8EPF9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

395965:MSIL RS15050
gene id: 395965:MSIL_RS15050
uniprot id: B8EIP9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

395965:MSIL RS19895
gene id: 395965:MSIL_RS19895
uniprot id: B8EMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395965:MSIL RS09505
gene id: 395965:MSIL_RS09505
uniprot id: B8ENM4
names: Similarity
messages: Belongs to the thioredoxin family.

395965:MSIL RS14720
gene id: 395965:MSIL_RS14720
uniprot id: B8ETG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

395965:MSIL RS18600
gene id: 395965:MSIL_RS18600
uniprot id: B8EJ55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. FixP subunit is required for transferring electrons from donor cytochrome c via its heme groups to FixO subunit. From there, electrons are shuttled to the catalytic binuclear center of FixN subunit where oxygen reduction takes place. The complex also functions as a proton pump.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase at least composed of FixN, FixO, FixQ and FixP.
messages: Membrane

395965:MSIL RS09755
gene id: 395965:MSIL_RS09755
uniprot id: B8ENR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

395965:MSIL RS14360
gene id: 395965:MSIL_RS14360
uniprot id: B8ET99
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS14295
gene id: 395965:MSIL_RS14295
uniprot id: B8ET86
names: Similarity
messages: Belongs to the phosphohexose mutase family.

395965:MSIL RS05620
gene id: 395965:MSIL_RS05620
uniprot id: B8ENC9
names: Similarity
messages: Belongs to the peptidase S58 family.

395965:MSIL RS13460
gene id: 395965:MSIL_RS13460
uniprot id: B8EQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS14545
gene id: 395965:MSIL_RS14545
uniprot id: B8ETD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

395965:MSIL RS08085
gene id: 395965:MSIL_RS08085
uniprot id: B8EI54
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

395965:MSIL RS03980
gene id: 395965:MSIL_RS03980
uniprot id: B8EQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS07765
gene id: 395965:MSIL_RS07765
uniprot id: B8EHY9
names: Similarity
messages: Belongs to the SCO1/2 family.

395965:MSIL RS12805
gene id: 395965:MSIL_RS12805
uniprot id: B8EM45
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

395965:MSIL RS01410
gene id: 395965:MSIL_RS01410
uniprot id: B8EP15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

395965:MSIL RS16645
gene id: 395965:MSIL_RS16645
uniprot id: B8EQG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

395965:MSIL RS05760
gene id: 395965:MSIL_RS05760
uniprot id: B8ENF6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

395965:MSIL RS09080
gene id: 395965:MSIL_RS09080
uniprot id: B8ELU5
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

395965:MSIL RS11165
gene id: 395965:MSIL_RS11165
uniprot id: B8ESY5
names: Similarity
messages: Belongs to the TPP enzyme family.

395965:MSIL RS13225
gene id: 395965:MSIL_RS13225
uniprot id: B8EQ28
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

395965:MSIL RS12950
gene id: 395965:MSIL_RS12950
uniprot id: B8EM75
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

395965:MSIL RS19495
gene id: 395965:MSIL_RS19495
uniprot id: B8EMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

395965:MSIL RS07695
gene id: 395965:MSIL_RS07695
uniprot id: B8EHX5
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS01525
gene id: 395965:MSIL_RS01525
uniprot id: B8EP38
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

395965:MSIL RS06045
gene id: 395965:MSIL_RS06045
uniprot id: B8ENL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

395965:MSIL RS02895
gene id: 395965:MSIL_RS02895
uniprot id: B8ELF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

395965:MSIL RS07710
gene id: 395965:MSIL_RS07710
uniprot id: B8EHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS02395
gene id: 395965:MSIL_RS02395
uniprot id: B8EJP0
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

395965:MSIL RS01415
gene id: 395965:MSIL_RS01415
uniprot id: B8EP16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

395965:MSIL RS10965
gene id: 395965:MSIL_RS10965
uniprot id: B8ERN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS12300
gene id: 395965:MSIL_RS12300
uniprot id: B8EKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS15445
gene id: 395965:MSIL_RS15445
uniprot id: B8EKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

395965:MSIL RS16095
gene id: 395965:MSIL_RS16095
uniprot id: B8EME0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

395965:MSIL RS14905
gene id: 395965:MSIL_RS14905
uniprot id: B8EIM8
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS10275
gene id: 395965:MSIL_RS10275
uniprot id: B8EPV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

395965:MSIL RS18030
gene id: 395965:MSIL_RS18030
uniprot id: B8ETT7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS15165
gene id: 395965:MSIL_RS15165
uniprot id: B8EIS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

395965:MSIL RS09370
gene id: 395965:MSIL_RS09370
uniprot id: B8EM02
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

395965:MSIL RS19345
gene id: 395965:MSIL_RS19345
uniprot id: B8EML2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

395965:MSIL RS00330
gene id: 395965:MSIL_RS00330
uniprot id: B8EL52
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS07720
gene id: 395965:MSIL_RS07720
uniprot id: B8EHY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

395965:MSIL RS09355
gene id: 395965:MSIL_RS09355
uniprot id: B8ELZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

395965:MSIL RS01765
gene id: 395965:MSIL_RS01765
uniprot id: B8EQQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

395965:MSIL RS00840
gene id: 395965:MSIL_RS00840
uniprot id: B8EN08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

395965:MSIL RS19035
gene id: 395965:MSIL_RS19035
uniprot id: B8EJD8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

395965:MSIL RS04305
gene id: 395965:MSIL_RS04305
uniprot id: B8ER60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

395965:MSIL RS03350
gene id: 395965:MSIL_RS03350
uniprot id: B8ENB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

395965:MSIL RS08960
gene id: 395965:MSIL_RS08960
uniprot id: B8ELS4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

395965:MSIL RS11280
gene id: 395965:MSIL_RS11280
uniprot id: B8ET05
names: Similarity
messages: Belongs to the HesB/IscA family.

395965:MSIL RS00300
gene id: 395965:MSIL_RS00300
uniprot id: B8EL46
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

395965:MSIL RS06150
gene id: 395965:MSIL_RS06150
uniprot id: B8EPF8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

395965:MSIL RS16375
gene id: 395965:MSIL_RS16375
uniprot id: B8EMJ5
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

395965:MSIL RS02510
gene id: 395965:MSIL_RS02510
uniprot id: B8EJR1
names: Similarity
messages: Belongs to the HesB/IscA family.

395965:MSIL RS06680
gene id: 395965:MSIL_RS06680
uniprot id: B8ER85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS00135
gene id: 395965:MSIL_RS00135
uniprot id: B8EL14
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

395965:MSIL RS16380
gene id: 395965:MSIL_RS16380
uniprot id: B8EQB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

395965:MSIL RS13210
gene id: 395965:MSIL_RS13210
uniprot id: B8EQ25
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

395965:MSIL RS01555
gene id: 395965:MSIL_RS01555
uniprot id: B8EP44
names: Similarity
messages: Belongs to the UPF0276 family.

395965:MSIL RS01795
gene id: 395965:MSIL_RS01795
uniprot id: B8EQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

395965:MSIL RS03580
gene id: 395965:MSIL_RS03580
uniprot id: B8EP83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

395965:MSIL RS19875
gene id: 395965:MSIL_RS19875
uniprot id: B8EMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS19640
gene id: 395965:MSIL_RS19640
uniprot id: B8EMS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

395965:MSIL RS07340
gene id: 395965:MSIL_RS07340
uniprot id: B8ESR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

395965:MSIL RS04270
gene id: 395965:MSIL_RS04270
uniprot id: B8ER53
names: Similarity
messages: Belongs to the universal stress protein A family.

395965:MSIL RS05915
gene id: 395965:MSIL_RS05915
uniprot id: B8ENI6
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

395965:MSIL RS00010
gene id: 395965:MSIL_RS00010
uniprot id: B8EJI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

395965:MSIL RS16405
gene id: 395965:MSIL_RS16405
uniprot id: B8EQB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

395965:MSIL RS09315
gene id: 395965:MSIL_RS09315
uniprot id: B8ELZ1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395965:MSIL RS13580
gene id: 395965:MSIL_RS13580
uniprot id: B8EQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

395965:MSIL RS01930
gene id: 395965:MSIL_RS01930
uniprot id: B8EQT4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395965:MSIL RS05130
gene id: 395965:MSIL_RS05130
uniprot id: B8EK16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

395965:MSIL RS04995
gene id: 395965:MSIL_RS04995
uniprot id: B8EJY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

395965:MSIL RS16145
gene id: 395965:MSIL_RS16145
uniprot id: B8EMF1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

395965:MSIL RS07375
gene id: 395965:MSIL_RS07375
uniprot id: B8ESS0
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

395965:MSIL RS01790
gene id: 395965:MSIL_RS01790
uniprot id: B8EQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

395965:MSIL RS10460
gene id: 395965:MSIL_RS10460
uniprot id: B8EPY5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

395965:MSIL RS04220
gene id: 395965:MSIL_RS04220
uniprot id: B8ER43
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

395965:MSIL RS09270
gene id: 395965:MSIL_RS09270
uniprot id: B8ELY2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

395965:MSIL RS16415
gene id: 395965:MSIL_RS16415
uniprot id: B8EQB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

395965:MSIL RS09815
gene id: 395965:MSIL_RS09815
uniprot id: B8ENT1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

395965:MSIL RS10835
gene id: 395965:MSIL_RS10835
uniprot id: B8ERK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

395965:MSIL RS02865
gene id: 395965:MSIL_RS02865
uniprot id: B8ELE6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

395965:MSIL RS13895
gene id: 395965:MSIL_RS13895
uniprot id: B8ERV4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS03075
gene id: 395965:MSIL_RS03075
uniprot id: B8EN64
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

395965:MSIL RS05230
gene id: 395965:MSIL_RS05230
uniprot id: B8ELI7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

395965:MSIL RS03340
gene id: 395965:MSIL_RS03340
uniprot id: B8ENB4
names: Similarity
messages: Belongs to the UPF0174 family.

395965:MSIL RS18100
gene id: 395965:MSIL_RS18100
uniprot id: B8EIW1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

395965:MSIL RS14610
gene id: 395965:MSIL_RS14610
uniprot id: B8ETE9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

395965:MSIL RS11170
gene id: 395965:MSIL_RS11170
uniprot id: B8ESY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS13800
gene id: 395965:MSIL_RS13800
uniprot id: B8ERT5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

395965:MSIL RS14825
gene id: 395965:MSIL_RS14825
uniprot id: B8EIL4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

395965:MSIL RS02910
gene id: 395965:MSIL_RS02910
uniprot id: B8ELF5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

395965:MSIL RS00600
gene id: 395965:MSIL_RS00600
uniprot id: B8ELA2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

395965:MSIL RS15380
gene id: 395965:MSIL_RS15380
uniprot id: B8EKP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

395965:MSIL RS16040
gene id: 395965:MSIL_RS16040
uniprot id: B8EMD0
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

395965:MSIL RS06460
gene id: 395965:MSIL_RS06460
uniprot id: B8EPM3
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

395965:MSIL RS03445
gene id: 395965:MSIL_RS03445
uniprot id: B8EP60
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

395965:MSIL RS09360
gene id: 395965:MSIL_RS09360
uniprot id: B8EM00
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

395965:MSIL RS00885
gene id: 395965:MSIL_RS00885
uniprot id: B8EN16
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395965:MSIL RS02995
gene id: 395965:MSIL_RS02995
uniprot id: B8ELH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

395965:MSIL RS08520
gene id: 395965:MSIL_RS08520
uniprot id: B8EK80
names: Similarity
messages: Belongs to the SufE family.

395965:MSIL RS15405
gene id: 395965:MSIL_RS15405
uniprot id: B8EKQ4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

395965:MSIL RS19650
gene id: 395965:MSIL_RS19650
uniprot id: B8EMS3
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS17150
gene id: 395965:MSIL_RS17150
uniprot id: B8ES61
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

395965:MSIL RS00905
gene id: 395965:MSIL_RS00905
uniprot id: B8EN20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

395965:MSIL RS04900
gene id: 395965:MSIL_RS04900
uniprot id: B8EJX1
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS05125
gene id: 395965:MSIL_RS05125
uniprot id: B8EK15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

395965:MSIL RS13045
gene id: 395965:MSIL_RS13045
uniprot id: B8EM94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

395965:MSIL RS01460
gene id: 395965:MSIL_RS01460
uniprot id: B8EP25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

395965:MSIL RS09735
gene id: 395965:MSIL_RS09735
uniprot id: B8ENR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

395965:MSIL RS13500
gene id: 395965:MSIL_RS13500
uniprot id: B8EQ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

395965:MSIL RS03985
gene id: 395965:MSIL_RS03985
uniprot id: B8EQZ9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS16725
gene id: 395965:MSIL_RS16725
uniprot id: B8EQI1
names: Subcellular Location Annotation
messages: Cytoplasm

395965:MSIL RS01920
gene id: 395965:MSIL_RS01920
uniprot id: B8EQT2
names: Similarity
messages: Belongs to the DNA photolyase family.

395965:MSIL RS10915
gene id: 395965:MSIL_RS10915
uniprot id: B8ERM4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS10235
gene id: 395965:MSIL_RS10235
uniprot id: B8EPU3
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS10370
gene id: 395965:MSIL_RS10370
uniprot id: B8EPW6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

395965:MSIL RS02055
gene id: 395965:MSIL_RS02055
uniprot id: B8EQV8
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

395965:MSIL RS11965
gene id: 395965:MSIL_RS11965
uniprot id: B8EIF3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

395965:MSIL RS03680
gene id: 395965:MSIL_RS03680
uniprot id: B8EPA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

395965:MSIL RS06360
gene id: 395965:MSIL_RS06360
uniprot id: B8EPK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

395965:MSIL RS02690
gene id: 395965:MSIL_RS02690
uniprot id: B8EJU7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

395965:MSIL RS05330
gene id: 395965:MSIL_RS05330
uniprot id: B8ELK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS05800
gene id: 395965:MSIL_RS05800
uniprot id: B8ENG3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS16780
gene id: 395965:MSIL_RS16780
uniprot id: B8EQJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

395965:MSIL RS10945
gene id: 395965:MSIL_RS10945
uniprot id: B8ERN0
names: Similarity
messages: Belongs to the AHA1 family.

395965:MSIL RS17700
gene id: 395965:MSIL_RS17700
uniprot id: B8ETM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS02595
gene id: 395965:MSIL_RS02595
uniprot id: B8EJS8
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

395965:MSIL RS02905
gene id: 395965:MSIL_RS02905
uniprot id: B8ELF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

395965:MSIL RS04655
gene id: 395965:MSIL_RS04655
uniprot id: B8ESI1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

395965:MSIL RS17675
gene id: 395965:MSIL_RS17675
uniprot id: B8ETL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

395965:MSIL RS13605
gene id: 395965:MSIL_RS13605
uniprot id: B8EQA5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS02000
gene id: 395965:MSIL_RS02000
uniprot id: B8EQU7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

395965:MSIL RS07175
gene id: 395965:MSIL_RS07175
uniprot id: B8ESN4
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

395965:MSIL RS00515
gene id: 395965:MSIL_RS00515
uniprot id: B8EL85
names: Similarity
messages: Belongs to the autoinducer synthase family.

395965:MSIL RS08625
gene id: 395965:MSIL_RS08625
uniprot id: B8EKA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

395965:MSIL RS16910
gene id: 395965:MSIL_RS16910
uniprot id: B8EQL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

395965:MSIL RS02880
gene id: 395965:MSIL_RS02880
uniprot id: B8ELE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

395965:MSIL RS11295
gene id: 395965:MSIL_RS11295
uniprot id: B8ET08
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

395965:MSIL RS12580
gene id: 395965:MSIL_RS12580
uniprot id: B8EKM4
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

395965:MSIL RS07575
gene id: 395965:MSIL_RS07575
uniprot id: B8ESV4
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

395965:MSIL RS13685
gene id: 395965:MSIL_RS13685
uniprot id: B8ERR2
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS02710
gene id: 395965:MSIL_RS02710
uniprot id: B8ELB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395965:MSIL RS06295
gene id: 395965:MSIL_RS06295
uniprot id: B8EPI9
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS12765
gene id: 395965:MSIL_RS12765
uniprot id: B8EM38
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

395965:MSIL RS07450
gene id: 395965:MSIL_RS07450
uniprot id: B8EST2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395965:MSIL RS03425
gene id: 395965:MSIL_RS03425
uniprot id: B8EP56
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS04255
gene id: 395965:MSIL_RS04255
uniprot id: B8ER50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

395965:MSIL RS10240
gene id: 395965:MSIL_RS10240
uniprot id: B8EPU4
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS18055
gene id: 395965:MSIL_RS18055
uniprot id: B8EIV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS07540
gene id: 395965:MSIL_RS07540
uniprot id: B8ESU7
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

395965:MSIL RS02855
gene id: 395965:MSIL_RS02855
uniprot id: B8ELE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

395965:MSIL RS10605
gene id: 395965:MSIL_RS10605
uniprot id: B8ERG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

395965:MSIL RS18955
gene id: 395965:MSIL_RS18955
uniprot id: B8EJC3
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

395965:MSIL RS03830
gene id: 395965:MSIL_RS03830
uniprot id: B8EPC6
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS17785
gene id: 395965:MSIL_RS17785
uniprot id: B8ETP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

395965:MSIL RS01420
gene id: 395965:MSIL_RS01420
uniprot id: B8EP17
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

395965:MSIL RS13325
gene id: 395965:MSIL_RS13325
uniprot id: B8EQ48
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

395965:MSIL RS06015
gene id: 395965:MSIL_RS06015
uniprot id: B8ENK5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

395965:MSIL RS03630
gene id: 395965:MSIL_RS03630
uniprot id: B8EP91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS08235
gene id: 395965:MSIL_RS08235
uniprot id: B8EI82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS18755
gene id: 395965:MSIL_RS18755
uniprot id: B8EJ84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

395965:MSIL RS15345
gene id: 395965:MSIL_RS15345
uniprot id: B8EKP2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

395965:MSIL RS08560
gene id: 395965:MSIL_RS08560
uniprot id: B8EK88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395965:MSIL RS00825
gene id: 395965:MSIL_RS00825
uniprot id: B8EN05
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

395965:MSIL RS13975
gene id: 395965:MSIL_RS13975
uniprot id: B8ERW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS16590
gene id: 395965:MSIL_RS16590
uniprot id: B8EQF4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

395965:MSIL RS14840
gene id: 395965:MSIL_RS14840
uniprot id: B8EIL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

395965:MSIL RS04490
gene id: 395965:MSIL_RS04490
uniprot id: B8ESF0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

395965:MSIL RS04540
gene id: 395965:MSIL_RS04540
uniprot id: B8ESF9
names: Similarity
messages: Belongs to the Gfa family.

395965:MSIL RS05035
gene id: 395965:MSIL_RS05035
uniprot id: B8EJZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

395965:MSIL RS05555
gene id: 395965:MSIL_RS05555
uniprot id: B8ELQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

395965:MSIL RS03585
gene id: 395965:MSIL_RS03585
uniprot id: B8EP84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS02220
gene id: 395965:MSIL_RS02220
uniprot id: B8EJK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS13690
gene id: 395965:MSIL_RS13690
uniprot id: B8ERR3
names: Similarity
messages: Belongs to the peptidase A24 family.

395965:MSIL RS03805
gene id: 395965:MSIL_RS03805
uniprot id: B8EPC1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

395965:MSIL RS17865
gene id: 395965:MSIL_RS17865
uniprot id: B8ETQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS19355
gene id: 395965:MSIL_RS19355
uniprot id: B8EML4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

395965:MSIL RS14895
gene id: 395965:MSIL_RS14895
uniprot id: B8EIM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS01640
gene id: 395965:MSIL_RS01640
uniprot id: B8EQM8
names: Similarity
messages: Belongs to the BolA/IbaG family.

395965:MSIL RS09455
gene id: 395965:MSIL_RS09455
uniprot id: B8ENL4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

395965:MSIL RS04100
gene id: 395965:MSIL_RS04100
uniprot id: B8ER20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

395965:MSIL RS18720
gene id: 395965:MSIL_RS18720
uniprot id: B8EJ78
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

395965:MSIL RS03955
gene id: 395965:MSIL_RS03955
uniprot id: B8EQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

395965:MSIL RS09280
gene id: 395965:MSIL_RS09280
uniprot id: B8ELY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

395965:MSIL RS13250
gene id: 395965:MSIL_RS13250
uniprot id: B8EQ33
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

395965:MSIL RS09950
gene id: 395965:MSIL_RS09950
uniprot id: B8ENV3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

395965:MSIL RS03810
gene id: 395965:MSIL_RS03810
uniprot id: B8EPC2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

395965:MSIL RS16365
gene id: 395965:MSIL_RS16365
uniprot id: B8EMJ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS09170
gene id: 395965:MSIL_RS09170
uniprot id: B8ELW2
names: Subcellular Location Annotation
messages: Cytoplasm

395965:MSIL RS17695
gene id: 395965:MSIL_RS17695
uniprot id: B8ETM3
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS16760
gene id: 395965:MSIL_RS16760
uniprot id: B8EQI8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

395965:MSIL RS02090
gene id: 395965:MSIL_RS02090
uniprot id: B8EQW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395965:MSIL RS11380
gene id: 395965:MSIL_RS11380
uniprot id: B8ET25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS08050
gene id: 395965:MSIL_RS08050
uniprot id: B8EI47
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

395965:MSIL RS09495
gene id: 395965:MSIL_RS09495
uniprot id: B8ENM2
names: Similarity
messages: Belongs to the UPF0434 family.

395965:MSIL RS12270
gene id: 395965:MSIL_RS12270
uniprot id: B8EKG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

395965:MSIL RS12995
gene id: 395965:MSIL_RS12995
uniprot id: B8EM84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

395965:MSIL RS06075
gene id: 395965:MSIL_RS06075
uniprot id: B8EPE3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

395965:MSIL RS16930
gene id: 395965:MSIL_RS16930
uniprot id: B8ES17
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

395965:MSIL RS06375
gene id: 395965:MSIL_RS06375
uniprot id: B8EPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS08600
gene id: 395965:MSIL_RS08600
uniprot id: B8EK95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

395965:MSIL RS17705
gene id: 395965:MSIL_RS17705
uniprot id: B8ETM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

395965:MSIL RS08675
gene id: 395965:MSIL_RS08675
uniprot id: B8EKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

395965:MSIL RS15655
gene id: 395965:MSIL_RS15655
uniprot id: B8EKV4
names: Similarity
messages: Belongs to the RecJ family.

395965:MSIL RS00370
gene id: 395965:MSIL_RS00370
uniprot id: B8EL60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

395965:MSIL RS08460
gene id: 395965:MSIL_RS08460
uniprot id: B8EK68
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

395965:MSIL RS13415
gene id: 395965:MSIL_RS13415
uniprot id: B8EQ67
names: Similarity
messages: Belongs to the glutamate synthase family.

395965:MSIL RS13620
gene id: 395965:MSIL_RS13620
uniprot id: B8EQA8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS09335
gene id: 395965:MSIL_RS09335
uniprot id: B8ELZ5
names: Function
messages: Multidrug efflux pump.

395965:MSIL RS03895
gene id: 395965:MSIL_RS03895
uniprot id: B8EQY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

395965:MSIL RS07200
gene id: 395965:MSIL_RS07200
uniprot id: B8ESN9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

395965:MSIL RS03365
gene id: 395965:MSIL_RS03365
uniprot id: B8ENB9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

395965:MSIL RS04005
gene id: 395965:MSIL_RS04005
uniprot id: B8ER03
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

395965:MSIL RS18645
gene id: 395965:MSIL_RS18645
uniprot id: B8EJ63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

395965:MSIL RS06170
gene id: 395965:MSIL_RS06170
uniprot id: B8EPG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

395965:MSIL RS00610
gene id: 395965:MSIL_RS00610
uniprot id: B8ELA5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

395965:MSIL RS18490
gene id: 395965:MSIL_RS18490
uniprot id: B8EJ33
names: Similarity
messages: Belongs to the NifZ family.

395965:MSIL RS00675
gene id: 395965:MSIL_RS00675
uniprot id: B8EMX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395965:MSIL RS04505
gene id: 395965:MSIL_RS04505
uniprot id: B8ESF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

395965:MSIL RS18980
gene id: 395965:MSIL_RS18980
uniprot id: B8EJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395965:MSIL RS16620
gene id: 395965:MSIL_RS16620
uniprot id: B8EQG0
names: Similarity
messages: Belongs to the CobH/CbiC family.

395965:MSIL RS18750
gene id: 395965:MSIL_RS18750
uniprot id: B8EJ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS10315
gene id: 395965:MSIL_RS10315
uniprot id: B8EPV6
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

395965:MSIL RS15040
gene id: 395965:MSIL_RS15040
uniprot id: B8EIP7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

395965:MSIL RS07285
gene id: 395965:MSIL_RS07285
uniprot id: B8ESQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

395965:MSIL RS09485
gene id: 395965:MSIL_RS09485
uniprot id: B8ENM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

395965:MSIL RS16135
gene id: 395965:MSIL_RS16135
uniprot id: B8EME9
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS16635
gene id: 395965:MSIL_RS16635
uniprot id: B8EQG3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

395965:MSIL RS13630
gene id: 395965:MSIL_RS13630
uniprot id: B8EQB0
names: Cofactor
messages: Binds 2 manganese ions per subunit.

395965:MSIL RS03635
gene id: 395965:MSIL_RS03635
uniprot id: B8EP92
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS08350
gene id: 395965:MSIL_RS08350
uniprot id: B8EK46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

395965:MSIL RS15190
gene id: 395965:MSIL_RS15190
uniprot id: B8EIS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

395965:MSIL RS09475
gene id: 395965:MSIL_RS09475
uniprot id: B8ENL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

395965:MSIL RS13790
gene id: 395965:MSIL_RS13790
uniprot id: B8ERT3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

395965:MSIL RS18775
gene id: 395965:MSIL_RS18775
uniprot id: B8EJ88
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

395965:MSIL RS18765
gene id: 395965:MSIL_RS18765
uniprot id: B8EJ86
names: Similarity
messages: Belongs to the UPF0276 family.

395965:MSIL RS19615
gene id: 395965:MSIL_RS19615
uniprot id: B8EMR6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

395965:MSIL RS04135
gene id: 395965:MSIL_RS04135
uniprot id: B8ER26
names: Function
names: Similarity
messages: Belongs to the CowN family.
messages: Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.

395965:MSIL RS14305
gene id: 395965:MSIL_RS14305
uniprot id: B8ET88
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

395965:MSIL RS14875
gene id: 395965:MSIL_RS14875
uniprot id: B8EIM2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

395965:MSIL RS08395
gene id: 395965:MSIL_RS08395
uniprot id: B8EK55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

395965:MSIL RS02380
gene id: 395965:MSIL_RS02380
uniprot id: B8EJN7
names: Similarity
messages: Belongs to the CopC family.

395965:MSIL RS06525
gene id: 395965:MSIL_RS06525
uniprot id: B8EPN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS14620
gene id: 395965:MSIL_RS14620
uniprot id: B8ETF1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

395965:MSIL RS01085
gene id: 395965:MSIL_RS01085
uniprot id: B8EN57
names: Similarity
messages: Belongs to the disproportionating enzyme family.
messages: Belongs to the glycosyl hydrolase 13 family.

395965:MSIL RS19815
gene id: 395965:MSIL_RS19815
uniprot id: B8EMV6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS01435
gene id: 395965:MSIL_RS01435
uniprot id: B8EP20
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

395965:MSIL RS03900
gene id: 395965:MSIL_RS03900
uniprot id: B8EQY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

395965:MSIL RS14000
gene id: 395965:MSIL_RS14000
uniprot id: B8ERX4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

395965:MSIL RS02545
gene id: 395965:MSIL_RS02545
uniprot id: B8EJR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

395965:MSIL RS10875
gene id: 395965:MSIL_RS10875
uniprot id: B8ERL6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395965:MSIL RS14810
gene id: 395965:MSIL_RS14810
uniprot id: B8EIL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

395965:MSIL RS00665
gene id: 395965:MSIL_RS00665
uniprot id: B8EMX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395965:MSIL RS04875
gene id: 395965:MSIL_RS04875
uniprot id: B8EJW6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395965:MSIL RS11410
gene id: 395965:MSIL_RS11410
uniprot id: B8ET31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

395965:MSIL RS18360
gene id: 395965:MSIL_RS18360
uniprot id: B8EJ07
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and reduces a quinone.
messages: Part of an electron transfer system.

395965:MSIL RS02010
gene id: 395965:MSIL_RS02010
uniprot id: B8EQU9
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

395965:MSIL RS19395
gene id: 395965:MSIL_RS19395
uniprot id: B8EMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

395965:MSIL RS09430
gene id: 395965:MSIL_RS09430
uniprot id: B8EM14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS09235
gene id: 395965:MSIL_RS09235
uniprot id: B8ELX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

395965:MSIL RS01925
gene id: 395965:MSIL_RS01925
uniprot id: B8EQT3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

395965:MSIL RS03575
gene id: 395965:MSIL_RS03575
uniprot id: B8EP82
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS05250
gene id: 395965:MSIL_RS05250
uniprot id: B8ELJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

395965:MSIL RS08465
gene id: 395965:MSIL_RS08465
uniprot id: B8EK69
names: Similarity
messages: Belongs to the UPF0260 family.

395965:MSIL RS07915
gene id: 395965:MSIL_RS07915
uniprot id: B8EI21
names: Similarity
messages: Belongs to the HsdR family.

395965:MSIL RS03820
gene id: 395965:MSIL_RS03820
uniprot id: B8EPC4
names: Similarity
messages: Belongs to the UPF0173 family.

395965:MSIL RS17735
gene id: 395965:MSIL_RS17735
uniprot id: B8ETN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

395965:MSIL RS01680
gene id: 395965:MSIL_RS01680
uniprot id: B8EQN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

395965:MSIL RS10820
gene id: 395965:MSIL_RS10820
uniprot id: B8ERK5
names: Similarity
messages: Belongs to the UPF0047 family.

395965:MSIL RS07145
gene id: 395965:MSIL_RS07145
uniprot id: B8ESM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS10335
gene id: 395965:MSIL_RS10335
uniprot id: B8EPV9
names: Similarity
messages: Belongs to the CFA/CMAS family.

395965:MSIL RS05920
gene id: 395965:MSIL_RS05920
uniprot id: B8ENI7
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

395965:MSIL RS05535
gene id: 395965:MSIL_RS05535
uniprot id: B8ELP9
names: Similarity
messages: Belongs to the peptidase C15 family.

395965:MSIL RS17725
gene id: 395965:MSIL_RS17725
uniprot id: B8ETN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

395965:MSIL RS17930
gene id: 395965:MSIL_RS17930
uniprot id: B8ETR7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

395965:MSIL RS01545
gene id: 395965:MSIL_RS01545
uniprot id: B8EP42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

395965:MSIL RS16455
gene id: 395965:MSIL_RS16455
uniprot id: B8EQC6
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS19450
gene id: 395965:MSIL_RS19450
uniprot id: B8EMN4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

395965:MSIL RS03435
gene id: 395965:MSIL_RS03435
uniprot id: B8EP58
names: Similarity
messages: Belongs to the heat shock protein 70 family.

395965:MSIL RS18090
gene id: 395965:MSIL_RS18090
uniprot id: B8EIV9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

395965:MSIL RS00765
gene id: 395965:MSIL_RS00765
uniprot id: B8EMZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

395965:MSIL RS02550
gene id: 395965:MSIL_RS02550
uniprot id: B8EJR9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

395965:MSIL RS01500
gene id: 395965:MSIL_RS01500
uniprot id: B8EP33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

395965:MSIL RS01585
gene id: 395965:MSIL_RS01585
uniprot id: B8EP50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

395965:MSIL RS09525
gene id: 395965:MSIL_RS09525
uniprot id: B8ENM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

395965:MSIL RS02265
gene id: 395965:MSIL_RS02265
uniprot id: B8EJL7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

395965:MSIL RS08195
gene id: 395965:MSIL_RS08195
uniprot id: B8EI74
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

395965:MSIL RS11795
gene id: 395965:MSIL_RS11795
uniprot id: B8EIC0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

395965:MSIL RS19540
gene id: 395965:MSIL_RS19540
uniprot id: B8EMQ1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

395965:MSIL RS01755
gene id: 395965:MSIL_RS01755
uniprot id: B8EQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

395965:MSIL RS03475
gene id: 395965:MSIL_RS03475
uniprot id: B8EP65
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

395965:MSIL RS06255
gene id: 395965:MSIL_RS06255
uniprot id: B8EPI1
names: Similarity
messages: Belongs to the GcvT family.

395965:MSIL RS14915
gene id: 395965:MSIL_RS14915
uniprot id: B8EIN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS13365
gene id: 395965:MSIL_RS13365
uniprot id: B8EQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

395965:MSIL RS00150
gene id: 395965:MSIL_RS00150
uniprot id: B8EL17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

395965:MSIL RS10960
gene id: 395965:MSIL_RS10960
uniprot id: B8ERN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

395965:MSIL RS08540
gene id: 395965:MSIL_RS08540
uniprot id: B8EK84
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

395965:MSIL RS07205
gene id: 395965:MSIL_RS07205
uniprot id: B8ESP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

395965:MSIL RS05020
gene id: 395965:MSIL_RS05020
uniprot id: B8EJZ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS07445
gene id: 395965:MSIL_RS07445
uniprot id: B8EST1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

395965:MSIL RS18365
gene id: 395965:MSIL_RS18365
uniprot id: B8EJ08
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

395965:MSIL RS18790
gene id: 395965:MSIL_RS18790
uniprot id: B8EJ91
names: Similarity
messages: Belongs to the UPF0335 family.

395965:MSIL RS19585
gene id: 395965:MSIL_RS19585
uniprot id: B8EMR0
names: Similarity
messages: Belongs to the DprA/Smf family.

395965:MSIL RS19645
gene id: 395965:MSIL_RS19645
uniprot id: B8EMS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

395965:MSIL RS00695
gene id: 395965:MSIL_RS00695
uniprot id: B8EMY2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

395965:MSIL RS02170
gene id: 395965:MSIL_RS02170
uniprot id: B8EQY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

395965:MSIL RS15315
gene id: 395965:MSIL_RS15315
uniprot id: B8EIU7
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS04425
gene id: 395965:MSIL_RS04425
uniprot id: B8ESD7
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS14465
gene id: 395965:MSIL_RS14465
uniprot id: B8ETC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS05910
gene id: 395965:MSIL_RS05910
uniprot id: B8ENI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

395965:MSIL RS01505
gene id: 395965:MSIL_RS01505
uniprot id: B8EP34
names: Similarity
messages: Belongs to the UPF0102 family.

395965:MSIL RS10910
gene id: 395965:MSIL_RS10910
uniprot id: B8ERM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS04405
gene id: 395965:MSIL_RS04405
uniprot id: B8ESD4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

395965:MSIL RS02915
gene id: 395965:MSIL_RS02915
uniprot id: B8ELF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

395965:MSIL RS11470
gene id: 395965:MSIL_RS11470
uniprot id: B8ET43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Cell inner membrane

395965:MSIL RS07385
gene id: 395965:MSIL_RS07385
uniprot id: B8ESS2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

395965:MSIL RS10555
gene id: 395965:MSIL_RS10555
uniprot id: B8EQ04
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

395965:MSIL RS12485
gene id: 395965:MSIL_RS12485
uniprot id: B8EKK4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395965:MSIL RS19460
gene id: 395965:MSIL_RS19460
uniprot id: B8EMN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

395965:MSIL RS01540
gene id: 395965:MSIL_RS01540
uniprot id: B8EP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395965:MSIL RS00620
gene id: 395965:MSIL_RS00620
uniprot id: B8ELA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

395965:MSIL RS18810
gene id: 395965:MSIL_RS18810
uniprot id: B8EJ95
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

395965:MSIL RS13475
gene id: 395965:MSIL_RS13475
uniprot id: B8EQ80
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

395965:MSIL RS18780
gene id: 395965:MSIL_RS18780
uniprot id: B8EJ89
names: Similarity
messages: Belongs to the UDPGP type 2 family.

395965:MSIL RS06885
gene id: 395965:MSIL_RS06885
uniprot id: B8ERC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

395965:MSIL RS04175
gene id: 395965:MSIL_RS04175
uniprot id: B8ER34
names: Similarity
messages: Belongs to the DinB family.

395965:MSIL RS11665
gene id: 395965:MSIL_RS11665
uniprot id: B8EI95
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

395965:MSIL RS08785
gene id: 395965:MSIL_RS08785
uniprot id: B8EKD1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

395965:MSIL RS01960
gene id: 395965:MSIL_RS01960
uniprot id: B8EQT9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS06240
gene id: 395965:MSIL_RS06240
uniprot id: B8EPH8
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

395965:MSIL RS05015
gene id: 395965:MSIL_RS05015
uniprot id: B8EJZ3
names: Subcellular Location Annotation
messages: Cytoplasm

395965:MSIL RS18975
gene id: 395965:MSIL_RS18975
uniprot id: B8EJC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395965:MSIL RS02555
gene id: 395965:MSIL_RS02555
uniprot id: B8EJS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

395965:MSIL RS10865
gene id: 395965:MSIL_RS10865
uniprot id: B8ERL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

395965:MSIL RS19910
gene id: 395965:MSIL_RS19910
uniprot id: B8EMX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

395965:MSIL RS17285
gene id: 395965:MSIL_RS17285
uniprot id: B8ES85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS19620
gene id: 395965:MSIL_RS19620
uniprot id: B8EMR7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

395965:MSIL RS02875
gene id: 395965:MSIL_RS02875
uniprot id: B8ELE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

395965:MSIL RS10995
gene id: 395965:MSIL_RS10995
uniprot id: B8ERN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

395965:MSIL RS04620
gene id: 395965:MSIL_RS04620
uniprot id: B8ESH4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

395965:MSIL RS01100
gene id: 395965:MSIL_RS01100
uniprot id: B8EN60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

395965:MSIL RS13575
gene id: 395965:MSIL_RS13575
uniprot id: B8EQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

395965:MSIL RS07550
gene id: 395965:MSIL_RS07550
uniprot id: B8ESU9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

395965:MSIL RS00945
gene id: 395965:MSIL_RS00945
uniprot id: B8EN30
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

395965:MSIL RS06420
gene id: 395965:MSIL_RS06420
uniprot id: B8EPL5
names: Similarity
messages: Belongs to the threonine synthase family.

395965:MSIL RS07415
gene id: 395965:MSIL_RS07415
uniprot id: B8ESS8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

395965:MSIL RS15475
gene id: 395965:MSIL_RS15475
uniprot id: B8EKR8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

395965:MSIL RS18550
gene id: 395965:MSIL_RS18550
uniprot id: B8EJ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

395965:MSIL RS08345
gene id: 395965:MSIL_RS08345
uniprot id: B8EK45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS12875
gene id: 395965:MSIL_RS12875
uniprot id: B8EM60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

395965:MSIL RS02850
gene id: 395965:MSIL_RS02850
uniprot id: B8ELE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

395965:MSIL RS15250
gene id: 395965:MSIL_RS15250
uniprot id: B8EIT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

395965:MSIL RS13510
gene id: 395965:MSIL_RS13510
uniprot id: B8EQ87
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

395965:MSIL RS17890
gene id: 395965:MSIL_RS17890
uniprot id: B8ETR0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

395965:MSIL RS05745
gene id: 395965:MSIL_RS05745
uniprot id: B8ENF3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

395965:MSIL RS12290
gene id: 395965:MSIL_RS12290
uniprot id: B8EKG6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

395965:MSIL RS18385
gene id: 395965:MSIL_RS18385
uniprot id: B8EJ12
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

395965:MSIL RS02920
gene id: 395965:MSIL_RS02920
uniprot id: B8ELF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

395965:MSIL RS13260
gene id: 395965:MSIL_RS13260
uniprot id: B8EQ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS03790
gene id: 395965:MSIL_RS03790
uniprot id: B8EPB9
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

395965:MSIL RS07290
gene id: 395965:MSIL_RS07290
uniprot id: B8ESQ7
names: Similarity
messages: Belongs to the peptidase M24B family.

395965:MSIL RS02945
gene id: 395965:MSIL_RS02945
uniprot id: B8ELG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

395965:MSIL RS11505
gene id: 395965:MSIL_RS11505
uniprot id: B8ET50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS02655
gene id: 395965:MSIL_RS02655
uniprot id: B8EJU0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

395965:MSIL RS01810
gene id: 395965:MSIL_RS01810
uniprot id: B8EQR1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS07965
gene id: 395965:MSIL_RS07965
uniprot id: B8EI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

395965:MSIL RS03360
gene id: 395965:MSIL_RS03360
uniprot id: B8ENB8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

395965:MSIL RS03735
gene id: 395965:MSIL_RS03735
uniprot id: B8EPB0
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

395965:MSIL RS10810
gene id: 395965:MSIL_RS10810
uniprot id: B8ERK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

395965:MSIL RS02950
gene id: 395965:MSIL_RS02950
uniprot id: B8ELG3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

395965:MSIL RS11995
gene id: 395965:MSIL_RS11995
uniprot id: B8EIF8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

395965:MSIL RS04355
gene id: 395965:MSIL_RS04355
uniprot id: B8ESC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

395965:MSIL RS05295
gene id: 395965:MSIL_RS05295
uniprot id: B8ELK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

395965:MSIL RS05960
gene id: 395965:MSIL_RS05960
uniprot id: B8ENJ5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

395965:MSIL RS00125
gene id: 395965:MSIL_RS00125
uniprot id: B8EL12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.

395965:MSIL RS03300
gene id: 395965:MSIL_RS03300
uniprot id: B8ENA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

395965:MSIL RS10525
gene id: 395965:MSIL_RS10525
uniprot id: B8EPZ8
names: Similarity
messages: Belongs to the PucC family.

395965:MSIL RS15465
gene id: 395965:MSIL_RS15465
uniprot id: B8EKR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

395965:MSIL RS15065
gene id: 395965:MSIL_RS15065
uniprot id: B8EIQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

395965:MSIL RS06120
gene id: 395965:MSIL_RS06120
uniprot id: B8EPF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

395965:MSIL RS17775
gene id: 395965:MSIL_RS17775
uniprot id: B8ETP0
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

395965:MSIL RS19420
gene id: 395965:MSIL_RS19420
uniprot id: B8EMM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

395965:MSIL RS06450
gene id: 395965:MSIL_RS06450
uniprot id: B8EPM1
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

395965:MSIL RS18495
gene id: 395965:MSIL_RS18495
uniprot id: B8EJ34
names: Similarity
messages: Belongs to the NifZ family.

395965:MSIL RS09895
gene id: 395965:MSIL_RS09895
uniprot id: B8ENU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS04230
gene id: 395965:MSIL_RS04230
uniprot id: B8ER45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

395965:MSIL RS16510
gene id: 395965:MSIL_RS16510
uniprot id: B8EQD7
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

395965:MSIL RS09825
gene id: 395965:MSIL_RS09825
uniprot id: B8ENT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS18310
gene id: 395965:MSIL_RS18310
uniprot id: B8EIZ7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

395965:MSIL RS19110
gene id: 395965:MSIL_RS19110
uniprot id: B8EJF3
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

395965:MSIL RS08860
gene id: 395965:MSIL_RS08860
uniprot id: B8EKE5
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

395965:MSIL RS11350
gene id: 395965:MSIL_RS11350
uniprot id: B8ET19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS18345
gene id: 395965:MSIL_RS18345
uniprot id: B8EJ04
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395965:MSIL RS14165
gene id: 395965:MSIL_RS14165
uniprot id: B8ES04
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

395965:MSIL RS09415
gene id: 395965:MSIL_RS09415
uniprot id: B8EM11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

395965:MSIL RS08355
gene id: 395965:MSIL_RS08355
uniprot id: B8EK47
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

395965:MSIL RS13520
gene id: 395965:MSIL_RS13520
uniprot id: B8EQ89
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

395965:MSIL RS03245
gene id: 395965:MSIL_RS03245
uniprot id: B8EN95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

395965:MSIL RS14520
gene id: 395965:MSIL_RS14520
uniprot id: B8ETD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

395965:MSIL RS14680
gene id: 395965:MSIL_RS14680
uniprot id: B8ETG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

395965:MSIL RS08330
gene id: 395965:MSIL_RS08330
uniprot id: B8EK42
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS19455
gene id: 395965:MSIL_RS19455
uniprot id: B8EMN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

395965:MSIL RS12850
gene id: 395965:MSIL_RS12850
uniprot id: B8EM54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

395965:MSIL RS14850
gene id: 395965:MSIL_RS14850
uniprot id: B8EIL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS08760
gene id: 395965:MSIL_RS08760
uniprot id: B8EKC6
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

395965:MSIL RS07135
gene id: 395965:MSIL_RS07135
uniprot id: B8ESM5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

395965:MSIL RS12330
gene id: 395965:MSIL_RS12330
uniprot id: B8EKH4
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS19060
gene id: 395965:MSIL_RS19060
uniprot id: B8EJE3
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

395965:MSIL RS18835
gene id: 395965:MSIL_RS18835
uniprot id: B8EJ99
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395965:MSIL RS03190
gene id: 395965:MSIL_RS03190
uniprot id: B8EN85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

395965:MSIL RS05010
gene id: 395965:MSIL_RS05010
uniprot id: B8EJZ2
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

395965:MSIL RS00980
gene id: 395965:MSIL_RS00980
uniprot id: B8EN37
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

395965:MSIL RS16660
gene id: 395965:MSIL_RS16660
uniprot id: B8EQG8
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

395965:MSIL RS11025
gene id: 395965:MSIL_RS11025
uniprot id: B8ERP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

395965:MSIL RS02750
gene id: 395965:MSIL_RS02750
uniprot id: B8ELC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395965:MSIL RS06695
gene id: 395965:MSIL_RS06695
uniprot id: B8ER88
names: Cofactor
messages: Binds 1 zinc ion per subunit.

395965:MSIL RS00215
gene id: 395965:MSIL_RS00215
uniprot id: B8EL30
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

395965:MSIL RS01720
gene id: 395965:MSIL_RS01720
uniprot id: B8EQP3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

395965:MSIL RS02050
gene id: 395965:MSIL_RS02050
uniprot id: B8EQV7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS16690
gene id: 395965:MSIL_RS16690
uniprot id: B8EQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

395965:MSIL RS01110
gene id: 395965:MSIL_RS01110
uniprot id: B8ENV9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

395965:MSIL RS08725
gene id: 395965:MSIL_RS08725
uniprot id: B8EKC0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

395965:MSIL RS09150
gene id: 395965:MSIL_RS09150
uniprot id: B8ELV8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

395965:MSIL RS05160
gene id: 395965:MSIL_RS05160
uniprot id: B8EK21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

395965:MSIL RS19900
gene id: 395965:MSIL_RS19900
uniprot id: B8EMX2
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

395965:MSIL RS07690
gene id: 395965:MSIL_RS07690
uniprot id: B8EHX4
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

395965:MSIL RS00755
gene id: 395965:MSIL_RS00755
uniprot id: B8EMZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

395965:MSIL RS19050
gene id: 395965:MSIL_RS19050
uniprot id: B8EJE1
names: Similarity
messages: Belongs to the HypD family.

395965:MSIL RS04695
gene id: 395965:MSIL_RS04695
uniprot id: B8ESI8
names: Similarity
messages: Belongs to the peptidase A24 family.

395965:MSIL RS16950
gene id: 395965:MSIL_RS16950
uniprot id: B8ES21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

395965:MSIL RS08185
gene id: 395965:MSIL_RS08185
uniprot id: B8EI72
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

395965:MSIL RS14340
gene id: 395965:MSIL_RS14340
uniprot id: B8ET95
names: Similarity
messages: Belongs to the AHA1 family.

395965:MSIL RS14365
gene id: 395965:MSIL_RS14365
uniprot id: B8ETA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

395965:MSIL RS10265
gene id: 395965:MSIL_RS10265
uniprot id: B8EPU9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

395965:MSIL RS09070
gene id: 395965:MSIL_RS09070
uniprot id: B8ELU3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

395965:MSIL RS06285
gene id: 395965:MSIL_RS06285
uniprot id: B8EPI7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

395965:MSIL RS11435
gene id: 395965:MSIL_RS11435
uniprot id: B8ET36
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

395965:MSIL RS16290
gene id: 395965:MSIL_RS16290
uniprot id: B8EMH9
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

395965:MSIL RS00895
gene id: 395965:MSIL_RS00895
uniprot id: B8EN18
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

395965:MSIL RS06080
gene id: 395965:MSIL_RS06080
uniprot id: B8EPE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

395965:MSIL RS11345
gene id: 395965:MSIL_RS11345
uniprot id: B8ET18
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS10675
gene id: 395965:MSIL_RS10675
uniprot id: B8ERH5
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS12045
gene id: 395965:MSIL_RS12045
uniprot id: B8EIG8
names: Similarity
messages: Belongs to the VgrG protein family.

395965:MSIL RS14910
gene id: 395965:MSIL_RS14910
uniprot id: B8EIM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

395965:MSIL RS04265
gene id: 395965:MSIL_RS04265
uniprot id: B8ER52
names: Similarity
messages: Belongs to the glutamate synthase family.

395965:MSIL RS11175
gene id: 395965:MSIL_RS11175
uniprot id: B8ESY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

395965:MSIL RS01320
gene id: 395965:MSIL_RS01320
uniprot id: B8ENZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ModE family.
messages: Cell inner membrane

395965:MSIL RS00645
gene id: 395965:MSIL_RS00645
uniprot id: B8ELB2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS02985
gene id: 395965:MSIL_RS02985
uniprot id: B8ELH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

395965:MSIL RS04190
gene id: 395965:MSIL_RS04190
uniprot id: B8ER37
names: Function
names: Similarity
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.

395965:MSIL RS02095
gene id: 395965:MSIL_RS02095
uniprot id: B8EQW6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS11260
gene id: 395965:MSIL_RS11260
uniprot id: B8ET01
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

395965:MSIL RS19270
gene id: 395965:MSIL_RS19270
uniprot id: B8EMJ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS12435
gene id: 395965:MSIL_RS12435
uniprot id: B8EKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

395965:MSIL RS19240
gene id: 395965:MSIL_RS19240
uniprot id: B8EJH8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

395965:MSIL RS18745
gene id: 395965:MSIL_RS18745
uniprot id: B8EJ82
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

395965:MSIL RS04095
gene id: 395965:MSIL_RS04095
uniprot id: B8ER19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

395965:MSIL RS10475
gene id: 395965:MSIL_RS10475
uniprot id: B8EPY8
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

395965:MSIL RS07505
gene id: 395965:MSIL_RS07505
uniprot id: B8ESU0
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

395965:MSIL RS13130
gene id: 395965:MSIL_RS13130
uniprot id: B8EQ09
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

395965:MSIL RS13165
gene id: 395965:MSIL_RS13165
uniprot id: B8EQ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

395965:MSIL RS16820
gene id: 395965:MSIL_RS16820
uniprot id: B8EQK0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395965:MSIL RS02630
gene id: 395965:MSIL_RS02630
uniprot id: B8EJT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS18390
gene id: 395965:MSIL_RS18390
uniprot id: B8EJ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

395965:MSIL RS05280
gene id: 395965:MSIL_RS05280
uniprot id: B8ELJ7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

395965:MSIL RS12400
gene id: 395965:MSIL_RS12400
uniprot id: B8EKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

395965:MSIL RS02255
gene id: 395965:MSIL_RS02255
uniprot id: B8EJL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

395965:MSIL RS17895
gene id: 395965:MSIL_RS17895
uniprot id: B8ETR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

395965:MSIL RS10920
gene id: 395965:MSIL_RS10920
uniprot id: B8ERM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS02790
gene id: 395965:MSIL_RS02790
uniprot id: B8ELD1
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

395965:MSIL RS10640
gene id: 395965:MSIL_RS10640
uniprot id: B8ERG9
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS20160
gene id: 395965:MSIL_RS20160
uniprot id: B8ENP1
names: Similarity
messages: Belongs to the virb1 family.

395965:MSIL RS15080
gene id: 395965:MSIL_RS15080
uniprot id: B8EIQ5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

395965:MSIL RS19505
gene id: 395965:MSIL_RS19505
uniprot id: B8EMP4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

395965:MSIL RS02935
gene id: 395965:MSIL_RS02935
uniprot id: B8ELG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

395965:MSIL RS13985
gene id: 395965:MSIL_RS13985
uniprot id: B8ERX1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

395965:MSIL RS00860
gene id: 395965:MSIL_RS00860
uniprot id: B8EN12
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS08765
gene id: 395965:MSIL_RS08765
uniprot id: B8EKC7
names: Similarity
messages: Belongs to the CutA family.

395965:MSIL RS15220
gene id: 395965:MSIL_RS15220
uniprot id: B8EIT1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

395965:MSIL RS06670
gene id: 395965:MSIL_RS06670
uniprot id: B8ER84
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS12365
gene id: 395965:MSIL_RS12365
uniprot id: B8EKI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

395965:MSIL RS14860
gene id: 395965:MSIL_RS14860
uniprot id: B8EIL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS02675
gene id: 395965:MSIL_RS02675
uniprot id: B8EJU4
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS18410
gene id: 395965:MSIL_RS18410
uniprot id: B8EJ17
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

395965:MSIL RS03155
gene id: 395965:MSIL_RS03155
uniprot id: B8EN78
names: Similarity
messages: Belongs to the Dps family.

395965:MSIL RS08830
gene id: 395965:MSIL_RS08830
uniprot id: B8EKE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

395965:MSIL RS18585
gene id: 395965:MSIL_RS18585
uniprot id: B8EJ52
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Cell membrane
messages: Membrane

395965:MSIL RS18095
gene id: 395965:MSIL_RS18095
uniprot id: B8EIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS02625
gene id: 395965:MSIL_RS02625
uniprot id: B8EJT4
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS05120
gene id: 395965:MSIL_RS05120
uniprot id: B8EK14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

395965:MSIL RS15180
gene id: 395965:MSIL_RS15180
uniprot id: B8EIS5
names: Similarity
messages: Belongs to the asparaginase 1 family.

395965:MSIL RS19515
gene id: 395965:MSIL_RS19515
uniprot id: B8EMP6
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS09460
gene id: 395965:MSIL_RS09460
uniprot id: B8ENL5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

395965:MSIL RS17605
gene id: 395965:MSIL_RS17605
uniprot id: B8ETK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

395965:MSIL RS11840
gene id: 395965:MSIL_RS11840
uniprot id: B8EIC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

395965:MSIL RS10510
gene id: 395965:MSIL_RS10510
uniprot id: B8EPZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Cellular chromatophore membrane
messages: Membrane
messages: Reaction center is composed of four bacteriochlorophylls, two bacteriopheophytins, two ubiquinones, one iron, and highly hydrophobic polypeptide chains.
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

395965:MSIL RS13600
gene id: 395965:MSIL_RS13600
uniprot id: B8EQA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS03125
gene id: 395965:MSIL_RS03125
uniprot id: B8EN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

395965:MSIL RS01800
gene id: 395965:MSIL_RS01800
uniprot id: B8EQQ9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

395965:MSIL RS00115
gene id: 395965:MSIL_RS00115
uniprot id: B8EL10
names: Similarity
messages: Belongs to the type III secretion exporter family.

395965:MSIL RS14415
gene id: 395965:MSIL_RS14415
uniprot id: B8ETB0
names: Similarity
messages: Belongs to the CmpA/NrtA family.

395965:MSIL RS19360
gene id: 395965:MSIL_RS19360
uniprot id: B8EML5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

395965:MSIL RS05565
gene id: 395965:MSIL_RS05565
uniprot id: B8ELQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395965:MSIL RS12550
gene id: 395965:MSIL_RS12550
uniprot id: B8EKL7
names: Similarity
messages: Belongs to the YciI family.

395965:MSIL RS06180
gene id: 395965:MSIL_RS06180
uniprot id: B8EPG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

395965:MSIL RS19115
gene id: 395965:MSIL_RS19115
uniprot id: B8EJF4
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

395965:MSIL RS14900
gene id: 395965:MSIL_RS14900
uniprot id: B8EIM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS06165
gene id: 395965:MSIL_RS06165
uniprot id: B8EPG1
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

395965:MSIL RS09765
gene id: 395965:MSIL_RS09765
uniprot id: B8ENS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

395965:MSIL RS11365
gene id: 395965:MSIL_RS11365
uniprot id: B8ET22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

395965:MSIL RS06365
gene id: 395965:MSIL_RS06365
uniprot id: B8EPK3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

395965:MSIL RS01035
gene id: 395965:MSIL_RS01035
uniprot id: B8EN48
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395965:MSIL RS00455
gene id: 395965:MSIL_RS00455
uniprot id: B8EL76
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

395965:MSIL RS06425
gene id: 395965:MSIL_RS06425
uniprot id: B8EPL6
names: Similarity
messages: Belongs to the peptidase M16 family.

395965:MSIL RS07170
gene id: 395965:MSIL_RS07170
uniprot id: B8ESN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

395965:MSIL RS00240
gene id: 395965:MSIL_RS00240
uniprot id: B8EL35
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

395965:MSIL RS04040
gene id: 395965:MSIL_RS04040
uniprot id: B8ER09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

395965:MSIL RS12990
gene id: 395965:MSIL_RS12990
uniprot id: B8EM83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

395965:MSIL RS04710
gene id: 395965:MSIL_RS04710
uniprot id: B8ESJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

395965:MSIL RS18510
gene id: 395965:MSIL_RS18510
uniprot id: B8EJ37
names: Similarity
messages: Belongs to the HesB/IscA family.

395965:MSIL RS12320
gene id: 395965:MSIL_RS12320
uniprot id: B8EKH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

395965:MSIL RS08550
gene id: 395965:MSIL_RS08550
uniprot id: B8EK86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

395965:MSIL RS02645
gene id: 395965:MSIL_RS02645
uniprot id: B8EJT8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

395965:MSIL RS06190
gene id: 395965:MSIL_RS06190
uniprot id: B8EPG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

395965:MSIL RS04285
gene id: 395965:MSIL_RS04285
uniprot id: B8ER56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

395965:MSIL RS06400
gene id: 395965:MSIL_RS06400
uniprot id: B8EPL1
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

395965:MSIL RS08190
gene id: 395965:MSIL_RS08190
uniprot id: B8EI73
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

395965:MSIL RS05850
gene id: 395965:MSIL_RS05850
uniprot id: B8ENH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

395965:MSIL RS12305
gene id: 395965:MSIL_RS12305
uniprot id: B8EKG9
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS11715
gene id: 395965:MSIL_RS11715
uniprot id: B8EIA5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

395965:MSIL RS08320
gene id: 395965:MSIL_RS08320
uniprot id: B8EK40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

395965:MSIL RS03050
gene id: 395965:MSIL_RS03050
uniprot id: B8ELI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS13335
gene id: 395965:MSIL_RS13335
uniprot id: B8EQ50
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS08125
gene id: 395965:MSIL_RS08125
uniprot id: B8EI62
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

395965:MSIL RS09060
gene id: 395965:MSIL_RS09060
uniprot id: B8ELU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

395965:MSIL RS08010
gene id: 395965:MSIL_RS08010
uniprot id: B8EI40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

395965:MSIL RS16650
gene id: 395965:MSIL_RS16650
uniprot id: B8EQG6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

395965:MSIL RS05410
gene id: 395965:MSIL_RS05410
uniprot id: B8ELM3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395965:MSIL RS16585
gene id: 395965:MSIL_RS16585
uniprot id: B8EQF3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

395965:MSIL RS11900
gene id: 395965:MSIL_RS11900
uniprot id: B8EIE0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

395965:MSIL RS08450
gene id: 395965:MSIL_RS08450
uniprot id: B8EK66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

395965:MSIL RS17730
gene id: 395965:MSIL_RS17730
uniprot id: B8ETN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

395965:MSIL RS02955
gene id: 395965:MSIL_RS02955
uniprot id: B8ELG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

395965:MSIL RS19305
gene id: 395965:MSIL_RS19305
uniprot id: B8EMK4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

395965:MSIL RS01590
gene id: 395965:MSIL_RS01590
uniprot id: B8EQL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

395965:MSIL RS11290
gene id: 395965:MSIL_RS11290
uniprot id: B8ET07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

395965:MSIL RS19630
gene id: 395965:MSIL_RS19630
uniprot id: B8EMR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

395965:MSIL RS06140
gene id: 395965:MSIL_RS06140
uniprot id: B8EPF6
names: Similarity
messages: Belongs to the phosphoribulokinase family.

395965:MSIL RS02930
gene id: 395965:MSIL_RS02930
uniprot id: B8ELF9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

395965:MSIL RS10515
gene id: 395965:MSIL_RS10515
uniprot id: B8EPZ6
names: Function
names: PTM
messages: Binds 4 heme groups per subunit.
messages: The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.

395965:MSIL RS10535
gene id: 395965:MSIL_RS10535
uniprot id: B8EQ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

395965:MSIL RS05420
gene id: 395965:MSIL_RS05420
uniprot id: B8ELM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

395965:MSIL RS00715
gene id: 395965:MSIL_RS00715
uniprot id: B8EMY6
names: Similarity
messages: Belongs to the LOG family.

395965:MSIL RS04840
gene id: 395965:MSIL_RS04840
uniprot id: B8EJV9
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS11785
gene id: 395965:MSIL_RS11785
uniprot id: B8EIB8
names: Similarity
messages: Belongs to the GST superfamily.

395965:MSIL RS03940
gene id: 395965:MSIL_RS03940
uniprot id: B8EQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

395965:MSIL RS03100
gene id: 395965:MSIL_RS03100
uniprot id: B8EN68
names: Subcellular Location Annotation
messages: Cell inner membrane

395965:MSIL RS11670
gene id: 395965:MSIL_RS11670
uniprot id: B8EI96
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395965:MSIL RS00165
gene id: 395965:MSIL_RS00165
uniprot id: B8EL20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

395965:MSIL RS15320
gene id: 395965:MSIL_RS15320
uniprot id: B8EKN7
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS19195
gene id: 395965:MSIL_RS19195
uniprot id: B8EJH0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

395965:MSIL RS04850
gene id: 395965:MSIL_RS04850
uniprot id: B8EJW1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS10680
gene id: 395965:MSIL_RS10680
uniprot id: B8ERH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

395965:MSIL RS18005
gene id: 395965:MSIL_RS18005
uniprot id: B8ETT2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

395965:MSIL RS00925
gene id: 395965:MSIL_RS00925
uniprot id: B8EN25
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

395965:MSIL RS00425
gene id: 395965:MSIL_RS00425
uniprot id: B8EL70
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS08280
gene id: 395965:MSIL_RS08280
uniprot id: B8EK33
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodecamer; pentamer of dimers.

395965:MSIL RS16310
gene id: 395965:MSIL_RS16310
uniprot id: B8EMI3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS01075
gene id: 395965:MSIL_RS01075
uniprot id: B8EN55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS01725
gene id: 395965:MSIL_RS01725
uniprot id: B8EQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

395965:MSIL RS01750
gene id: 395965:MSIL_RS01750
uniprot id: B8EQP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

395965:MSIL RS04930
gene id: 395965:MSIL_RS04930
uniprot id: B8EJX6
names: Similarity
messages: Belongs to the DEAD box helicase family.

395965:MSIL RS14855
gene id: 395965:MSIL_RS14855
uniprot id: B8EIL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS18845
gene id: 395965:MSIL_RS18845
uniprot id: B8EJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

395965:MSIL RS03200
gene id: 395965:MSIL_RS03200
uniprot id: B8EN87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS04310
gene id: 395965:MSIL_RS04310
uniprot id: B8ER61
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS06185
gene id: 395965:MSIL_RS06185
uniprot id: B8EPG6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

395965:MSIL RS13775
gene id: 395965:MSIL_RS13775
uniprot id: B8ERT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

395965:MSIL RS02515
gene id: 395965:MSIL_RS02515
uniprot id: B8EJR2
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

395965:MSIL RS06865
gene id: 395965:MSIL_RS06865
uniprot id: B8ERC3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

395965:MSIL RS14555
gene id: 395965:MSIL_RS14555
uniprot id: B8ETD8
names: Similarity
messages: Belongs to the peptidase M16 family.

395965:MSIL RS12790
gene id: 395965:MSIL_RS12790
uniprot id: B8EM42
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

395965:MSIL RS17615
gene id: 395965:MSIL_RS17615
uniprot id: B8ETK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

395965:MSIL RS13720
gene id: 395965:MSIL_RS13720
uniprot id: B8ERR9
names: Similarity
messages: Belongs to the bacterial secretin family.

395965:MSIL RS01610
gene id: 395965:MSIL_RS01610
uniprot id: B8EQM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

395965:MSIL RS18565
gene id: 395965:MSIL_RS18565
uniprot id: B8EJ48
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

395965:MSIL RS00740
gene id: 395965:MSIL_RS00740
uniprot id: B8EMZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

395965:MSIL RS13970
gene id: 395965:MSIL_RS13970
uniprot id: B8ERW8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

395965:MSIL RS18560
gene id: 395965:MSIL_RS18560
uniprot id: B8EJ47
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

395965:MSIL RS00160
gene id: 395965:MSIL_RS00160
uniprot id: B8EL19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

395965:MSIL RS16560
gene id: 395965:MSIL_RS16560
uniprot id: B8EQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

395965:MSIL RS19610
gene id: 395965:MSIL_RS19610
uniprot id: B8EMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

395965:MSIL RS00995
gene id: 395965:MSIL_RS00995
uniprot id: B8EN40
names: Similarity
messages: Belongs to the peptidase M1 family.

395965:MSIL RS15010
gene id: 395965:MSIL_RS15010
uniprot id: B8EIP3
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS11320
gene id: 395965:MSIL_RS11320
uniprot id: B8ET13
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

395965:MSIL RS18355
gene id: 395965:MSIL_RS18355
uniprot id: B8EJ06
names: Function
names: Similarity
messages: Could be a 3Fe-4S cluster-containing protein.
messages: To ferredoxins from P.putida and C.tartarivorum, ferredoxin I from A.vinelandii, ferredoxin II from D.desulfuricans.

395965:MSIL RS18045
gene id: 395965:MSIL_RS18045
uniprot id: B8EIV0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

395965:MSIL RS16720
gene id: 395965:MSIL_RS16720
uniprot id: B8EQI0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

395965:MSIL RS07210
gene id: 395965:MSIL_RS07210
uniprot id: B8ESP1
names: Similarity
messages: Belongs to the thioredoxin family.

395965:MSIL RS19915
gene id: 395965:MSIL_RS19915
uniprot id: B8EMX4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

395965:MSIL RS19580
gene id: 395965:MSIL_RS19580
uniprot id: B8EMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

395965:MSIL RS02890
gene id: 395965:MSIL_RS02890
uniprot id: B8ELF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

395965:MSIL RS04315
gene id: 395965:MSIL_RS04315
uniprot id: B8ESB7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395965:MSIL RS16010
gene id: 395965:MSIL_RS16010
uniprot id: B8EMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

395965:MSIL RS07590
gene id: 395965:MSIL_RS07590
uniprot id: B8ESV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

395965:MSIL RS05210
gene id: 395965:MSIL_RS05210
uniprot id: B8EK30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

395965:MSIL RS11405
gene id: 395965:MSIL_RS11405
uniprot id: B8ET30
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS00520
gene id: 395965:MSIL_RS00520
uniprot id: B8EL86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS13505
gene id: 395965:MSIL_RS13505
uniprot id: B8EQ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

395965:MSIL RS20000
gene id: 395965:MSIL_RS20000
uniprot id: B8ELH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

395965:MSIL RS06160
gene id: 395965:MSIL_RS06160
uniprot id: B8EPG0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

395965:MSIL RS16670
gene id: 395965:MSIL_RS16670
uniprot id: B8EQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

395965:MSIL RS11305
gene id: 395965:MSIL_RS11305
uniprot id: B8ET10
names: Similarity
messages: Belongs to the AHA1 family.

395965:MSIL RS12785
gene id: 395965:MSIL_RS12785
uniprot id: B8EM41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

395965:MSIL RS01250
gene id: 395965:MSIL_RS01250
uniprot id: B8ENY4
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

395965:MSIL RS19125
gene id: 395965:MSIL_RS19125
uniprot id: B8EJF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS13945
gene id: 395965:MSIL_RS13945
uniprot id: B8ERW3
names: Similarity
messages: Belongs to the HypE family.

395965:MSIL RS10695
gene id: 395965:MSIL_RS10695
uniprot id: B8ERH9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

395965:MSIL RS12535
gene id: 395965:MSIL_RS12535
uniprot id: B8EKL4
names: Similarity
messages: Belongs to the NTE family.

395965:MSIL RS18710
gene id: 395965:MSIL_RS18710
uniprot id: B8EJ76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS00440
gene id: 395965:MSIL_RS00440
uniprot id: B8EL73
names: Similarity
messages: Belongs to the acylphosphatase family.

395965:MSIL RS15295
gene id: 395965:MSIL_RS15295
uniprot id: B8EIU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

395965:MSIL RS17540
gene id: 395965:MSIL_RS17540
uniprot id: B8ETJ2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395965:MSIL RS10830
gene id: 395965:MSIL_RS10830
uniprot id: B8ERK7
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS10885
gene id: 395965:MSIL_RS10885
uniprot id: B8ERL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS16420
gene id: 395965:MSIL_RS16420
uniprot id: B8EQB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

395965:MSIL RS03825
gene id: 395965:MSIL_RS03825
uniprot id: B8EPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

395965:MSIL RS02230
gene id: 395965:MSIL_RS02230
uniprot id: B8EJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

395965:MSIL RS00025
gene id: 395965:MSIL_RS00025
uniprot id: B8EJI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

395965:MSIL RS14885
gene id: 395965:MSIL_RS14885
uniprot id: B8EIM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

395965:MSIL RS09330
gene id: 395965:MSIL_RS09330
uniprot id: B8ELZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

395965:MSIL RS16805
gene id: 395965:MSIL_RS16805
uniprot id: B8EQJ7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

395965:MSIL RS03570
gene id: 395965:MSIL_RS03570
uniprot id: B8EP81
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

395965:MSIL RS04645
gene id: 395965:MSIL_RS04645
uniprot id: B8ESH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

395965:MSIL RS03010
gene id: 395965:MSIL_RS03010
uniprot id: B8ELH5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

395965:MSIL RS19280
gene id: 395965:MSIL_RS19280
uniprot id: B8EMJ9
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS05355
gene id: 395965:MSIL_RS05355
uniprot id: B8ELL2
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS09275
gene id: 395965:MSIL_RS09275
uniprot id: B8ELY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

395965:MSIL RS19040
gene id: 395965:MSIL_RS19040
uniprot id: B8EJD9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

395965:MSIL RS17085
gene id: 395965:MSIL_RS17085
uniprot id: B8ES49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BA14k family.
messages: Cell membrane
messages: Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.
messages: Membrane

395965:MSIL RS00140
gene id: 395965:MSIL_RS00140
uniprot id: B8EL15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

395965:MSIL RS12525
gene id: 395965:MSIL_RS12525
uniprot id: B8EKL2
names: Similarity
messages: Belongs to the glutathione peroxidase family.

395965:MSIL RS19200
gene id: 395965:MSIL_RS19200
uniprot id: B8EJH1
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

395965:MSIL RS04250
gene id: 395965:MSIL_RS04250
uniprot id: B8ER49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

395965:MSIL RS08945
gene id: 395965:MSIL_RS08945
uniprot id: B8ELS1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

395965:MSIL RS16975
gene id: 395965:MSIL_RS16975
uniprot id: B8ES26
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

395965:MSIL RS02980
gene id: 395965:MSIL_RS02980
uniprot id: B8ELG9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

395965:MSIL RS09830
gene id: 395965:MSIL_RS09830
uniprot id: B8ENT4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395965:MSIL RS13060
gene id: 395965:MSIL_RS13060
uniprot id: B8EM97
names: Similarity
messages: Belongs to the pirin family.

395965:MSIL RS03395
gene id: 395965:MSIL_RS03395
uniprot id: B8ENC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

395965:MSIL RS17570
gene id: 395965:MSIL_RS17570
uniprot id: B8ETJ8
names: Similarity
messages: Belongs to the nitrile hydratase subunit alpha family.

395965:MSIL RS00585
gene id: 395965:MSIL_RS00585
uniprot id: B8EL99
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

395965:MSIL RS03850
gene id: 395965:MSIL_RS03850
uniprot id: B8EPD0
names: Similarity
messages: Belongs to the ClpA/ClpB family.

395965:MSIL RS15255
gene id: 395965:MSIL_RS15255
uniprot id: B8EIT5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

395965:MSIL RS00100
gene id: 395965:MSIL_RS00100
uniprot id: B8EL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

395965:MSIL RS11400
gene id: 395965:MSIL_RS11400
uniprot id: B8ET29
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

395965:MSIL RS05845
gene id: 395965:MSIL_RS05845
uniprot id: B8ENH2
names: Subcellular Location Annotation
messages: Mitochondrion

395965:MSIL RS15460
gene id: 395965:MSIL_RS15460
uniprot id: B8EKR4
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS07560
gene id: 395965:MSIL_RS07560
uniprot id: B8ESV1
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

395965:MSIL RS18870
gene id: 395965:MSIL_RS18870
uniprot id: B8EJA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS15645
gene id: 395965:MSIL_RS15645
uniprot id: B8EKV2
names: Similarity
messages: Belongs to the UPF0262 family.

395965:MSIL RS14510
gene id: 395965:MSIL_RS14510
uniprot id: B8ETC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

395965:MSIL RS12355
gene id: 395965:MSIL_RS12355
uniprot id: B8EKH9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

395965:MSIL RS04510
gene id: 395965:MSIL_RS04510
uniprot id: B8ESF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

395965:MSIL RS00335
gene id: 395965:MSIL_RS00335
uniprot id: B8EL53
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS18445
gene id: 395965:MSIL_RS18445
uniprot id: B8EJ24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

395965:MSIL RS07165
gene id: 395965:MSIL_RS07165
uniprot id: B8ESN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

395965:MSIL RS07955
gene id: 395965:MSIL_RS07955
uniprot id: B8EI29
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

395965:MSIL RS05475
gene id: 395965:MSIL_RS05475
uniprot id: B8ELN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

395965:MSIL RS06485
gene id: 395965:MSIL_RS06485
uniprot id: B8EPM8
names: Similarity
messages: Belongs to the TmoD/XamoD family.

395965:MSIL RS02720
gene id: 395965:MSIL_RS02720
uniprot id: B8ELB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

395965:MSIL RS17270
gene id: 395965:MSIL_RS17270
uniprot id: B8ES82
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS12430
gene id: 395965:MSIL_RS12430
uniprot id: B8EKJ3
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS03460
gene id: 395965:MSIL_RS03460
uniprot id: B8EP62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

395965:MSIL RS16880
gene id: 395965:MSIL_RS16880
uniprot id: B8EQL1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

395965:MSIL RS15340
gene id: 395965:MSIL_RS15340
uniprot id: B8EKP1
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

395965:MSIL RS08525
gene id: 395965:MSIL_RS08525
uniprot id: B8EK81
names: Similarity
messages: Belongs to the ros/MucR family.

395965:MSIL RS18075
gene id: 395965:MSIL_RS18075
uniprot id: B8EIV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS18530
gene id: 395965:MSIL_RS18530
uniprot id: B8EJ41
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

395965:MSIL RS15975
gene id: 395965:MSIL_RS15975
uniprot id: B8EMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

395965:MSIL RS02885
gene id: 395965:MSIL_RS02885
uniprot id: B8ELF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

395965:MSIL RS03865
gene id: 395965:MSIL_RS03865
uniprot id: B8EPD3
names: Similarity
messages: Belongs to the peptidase S11 family.

395965:MSIL RS04770
gene id: 395965:MSIL_RS04770
uniprot id: B8ESK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

395965:MSIL RS05865
gene id: 395965:MSIL_RS05865
uniprot id: B8ENH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

395965:MSIL RS01095
gene id: 395965:MSIL_RS01095
uniprot id: B8EN59
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

395965:MSIL RS06710
gene id: 395965:MSIL_RS06710
uniprot id: B8ER92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS08315
gene id: 395965:MSIL_RS08315
uniprot id: B8EK39
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395965:MSIL RS10365
gene id: 395965:MSIL_RS10365
uniprot id: B8EPW5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

395965:MSIL RS11780
gene id: 395965:MSIL_RS11780
uniprot id: B8EIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

395965:MSIL RS15795
gene id: 395965:MSIL_RS15795
uniprot id: B8EKY2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

395965:MSIL RS11875
gene id: 395965:MSIL_RS11875
uniprot id: B8EID6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

395965:MSIL RS12385
gene id: 395965:MSIL_RS12385
uniprot id: B8EKI5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

395965:MSIL RS06110
gene id: 395965:MSIL_RS06110
uniprot id: B8EPF0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

395965:MSIL RS05985
gene id: 395965:MSIL_RS05985
uniprot id: B8ENJ9
names: Similarity
messages: Belongs to the creatininase superfamily.

395965:MSIL RS10690
gene id: 395965:MSIL_RS10690
uniprot id: B8ERH8
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

395965:MSIL RS14475
gene id: 395965:MSIL_RS14475
uniprot id: B8ETC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

395965:MSIL RS11325
gene id: 395965:MSIL_RS11325
uniprot id: B8ET14
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS14770
gene id: 395965:MSIL_RS14770
uniprot id: B8ETH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

395965:MSIL RS06040
gene id: 395965:MSIL_RS06040
uniprot id: B8ENL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

395965:MSIL RS10775
gene id: 395965:MSIL_RS10775
uniprot id: B8ERJ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS05765
gene id: 395965:MSIL_RS05765
uniprot id: B8ENF7
names: Similarity
messages: Belongs to the AHA1 family.

395965:MSIL RS07140
gene id: 395965:MSIL_RS07140
uniprot id: B8ESM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395965:MSIL RS10100
gene id: 395965:MSIL_RS10100
uniprot id: B8EPR7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395965:MSIL RS08630
gene id: 395965:MSIL_RS08630
uniprot id: B8EKA1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

395965:MSIL RS06085
gene id: 395965:MSIL_RS06085
uniprot id: B8EPE5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

395965:MSIL RS19775
gene id: 395965:MSIL_RS19775
uniprot id: B8EMU6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS00055
gene id: 395965:MSIL_RS00055
uniprot id: B8EJJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS11360
gene id: 395965:MSIL_RS11360
uniprot id: B8ET21
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

395965:MSIL RS14420
gene id: 395965:MSIL_RS14420
uniprot id: B8ETB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS07745
gene id: 395965:MSIL_RS07745
uniprot id: B8EHY5
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

395965:MSIL RS14865
gene id: 395965:MSIL_RS14865
uniprot id: B8EIM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS01155
gene id: 395965:MSIL_RS01155
uniprot id: B8ENW7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

395965:MSIL RS10635
gene id: 395965:MSIL_RS10635
uniprot id: B8ERG8
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS16895
gene id: 395965:MSIL_RS16895
uniprot id: B8EQL4
names: Function
messages: Multidrug efflux pump.

395965:MSIL RS07000
gene id: 395965:MSIL_RS07000
uniprot id: B8ERE9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

395965:MSIL RS10990
gene id: 395965:MSIL_RS10990
uniprot id: B8ERN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

395965:MSIL RS04775
gene id: 395965:MSIL_RS04775
uniprot id: B8ESK3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

395965:MSIL RS01025
gene id: 395965:MSIL_RS01025
uniprot id: B8EN46
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

395965:MSIL RS19510
gene id: 395965:MSIL_RS19510
uniprot id: B8EMP5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

395965:MSIL RS09285
gene id: 395965:MSIL_RS09285
uniprot id: B8ELY5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395965:MSIL RS02650
gene id: 395965:MSIL_RS02650
uniprot id: B8EJT9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

395965:MSIL RS10595
gene id: 395965:MSIL_RS10595
uniprot id: B8ERG1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

395965:MSIL RS15260
gene id: 395965:MSIL_RS15260
uniprot id: B8EIT6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

395965:MSIL RS09225
gene id: 395965:MSIL_RS09225
uniprot id: B8ELX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

395965:MSIL RS01980
gene id: 395965:MSIL_RS01980
uniprot id: B8EQU3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

395965:MSIL RS05390
gene id: 395965:MSIL_RS05390
uniprot id: B8ELL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

395965:MSIL RS08900
gene id: 395965:MSIL_RS08900
uniprot id: B8EKF3
names: Similarity
messages: Belongs to the YciI family.

395965:MSIL RS02310
gene id: 395965:MSIL_RS02310
uniprot id: B8EJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

395965:MSIL RS18985
gene id: 395965:MSIL_RS18985
uniprot id: B8EJC9
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

395965:MSIL RS09190
gene id: 395965:MSIL_RS09190
uniprot id: B8ELW6
names: Subcellular Location Annotation
messages: Nucleus

395965:MSIL RS03330
gene id: 395965:MSIL_RS03330
uniprot id: B8ENB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

395965:MSIL RS02760
gene id: 395965:MSIL_RS02760
uniprot id: B8ELC6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

395965:MSIL RS07300
gene id: 395965:MSIL_RS07300
uniprot id: B8ESQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

395965:MSIL RS06105
gene id: 395965:MSIL_RS06105
uniprot id: B8EPE9
names: Similarity
messages: Belongs to the BolA/IbaG family.

395965:MSIL RS05660
gene id: 395965:MSIL_RS05660
uniprot id: B8END7
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

395965:MSIL RS04615
gene id: 395965:MSIL_RS04615
uniprot id: B8ESH3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

395965:MSIL RS03540
gene id: 395965:MSIL_RS03540
uniprot id: B8EP76
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS19430
gene id: 395965:MSIL_RS19430
uniprot id: B8EMM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

395965:MSIL RS11820
gene id: 395965:MSIL_RS11820
uniprot id: B8EIC5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

395965:MSIL RS17670
gene id: 395965:MSIL_RS17670
uniprot id: B8ETL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

395965:MSIL RS08445
gene id: 395965:MSIL_RS08445
uniprot id: B8EK65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm
messages: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.

395965:MSIL RS03905
gene id: 395965:MSIL_RS03905
uniprot id: B8EQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

395965:MSIL RS07100
gene id: 395965:MSIL_RS07100
uniprot id: B8ESL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

395965:MSIL RS02960
gene id: 395965:MSIL_RS02960
uniprot id: B8ELG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

395965:MSIL RS01820
gene id: 395965:MSIL_RS01820
uniprot id: B8EQR4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

395965:MSIL RS19335
gene id: 395965:MSIL_RS19335
uniprot id: B8EML0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

395965:MSIL RS11690
gene id: 395965:MSIL_RS11690
uniprot id: B8EIA0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

395965:MSIL RS13455
gene id: 395965:MSIL_RS13455
uniprot id: B8EQ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

395965:MSIL RS14820
gene id: 395965:MSIL_RS14820
uniprot id: B8EIL3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

395965:MSIL RS03480
gene id: 395965:MSIL_RS03480
uniprot id: B8EP66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

395965:MSIL RS06300
gene id: 395965:MSIL_RS06300
uniprot id: B8EPJ0
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

395965:MSIL RS03970
gene id: 395965:MSIL_RS03970
uniprot id: B8EQZ6
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

395965:MSIL RS02640
gene id: 395965:MSIL_RS02640
uniprot id: B8EJT7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

395965:MSIL RS03070
gene id: 395965:MSIL_RS03070
uniprot id: B8EN63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

395965:MSIL RS19880
gene id: 395965:MSIL_RS19880
uniprot id: B8EMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS03535
gene id: 395965:MSIL_RS03535
uniprot id: B8EP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395965:MSIL RS10170
gene id: 395965:MSIL_RS10170
uniprot id: B8EPT0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

395965:MSIL RS10355
gene id: 395965:MSIL_RS10355
uniprot id: B8EPW3
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS01745
gene id: 395965:MSIL_RS01745
uniprot id: B8EQP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

395965:MSIL RS16245
gene id: 395965:MSIL_RS16245
uniprot id: B8EMH0
names: PTM
names: Subcellular Location Annotation
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm

395965:MSIL RS00535
gene id: 395965:MSIL_RS00535
uniprot id: B8EL89
names: Similarity
messages: Belongs to the ArsC family.

395965:MSIL RS04075
gene id: 395965:MSIL_RS04075
uniprot id: B8ER15
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

395965:MSIL RS09400
gene id: 395965:MSIL_RS09400
uniprot id: B8EM08
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS06995
gene id: 395965:MSIL_RS06995
uniprot id: B8ERE8
names: Similarity
messages: Belongs to the peptidase S11 family.

395965:MSIL RS10280
gene id: 395965:MSIL_RS10280
uniprot id: B8EPV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

395965:MSIL RS18730
gene id: 395965:MSIL_RS18730
uniprot id: B8EJ79
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

395965:MSIL RS04350
gene id: 395965:MSIL_RS04350
uniprot id: B8ESC4
names: Similarity
messages: Belongs to the histone deacetylase family.

395965:MSIL RS13065
gene id: 395965:MSIL_RS13065
uniprot id: B8EM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS18470
gene id: 395965:MSIL_RS18470
uniprot id: B8EJ29
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

395965:MSIL RS11045
gene id: 395965:MSIL_RS11045
uniprot id: B8ERP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

395965:MSIL RS08500
gene id: 395965:MSIL_RS08500
uniprot id: B8EK76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

395965:MSIL RS08720
gene id: 395965:MSIL_RS08720
uniprot id: B8EKB9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

395965:MSIL RS10505
gene id: 395965:MSIL_RS10505
uniprot id: B8EPZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Membrane
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

395965:MSIL RS13955
gene id: 395965:MSIL_RS13955
uniprot id: B8ERW5
names: Similarity
messages: Belongs to the HupF/HypC family.

395965:MSIL RS04145
gene id: 395965:MSIL_RS04145
uniprot id: B8ER28
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

395965:MSIL RS11475
gene id: 395965:MSIL_RS11475
uniprot id: B8ET44
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

395965:MSIL RS02285
gene id: 395965:MSIL_RS02285
uniprot id: B8EJM0
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

395965:MSIL RS04705
gene id: 395965:MSIL_RS04705
uniprot id: B8ESJ0
names: Similarity
messages: Belongs to the GSP E family.

395965:MSIL RS13610
gene id: 395965:MSIL_RS13610
uniprot id: B8EQA6
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

395965:MSIL RS00640
gene id: 395965:MSIL_RS00640
uniprot id: B8ELB1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

395965:MSIL RS19600
gene id: 395965:MSIL_RS19600
uniprot id: B8EMR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

395965:MSIL RS16825
gene id: 395965:MSIL_RS16825
uniprot id: B8EQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS18820
gene id: 395965:MSIL_RS18820
uniprot id: B8EJ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

395965:MSIL RS05000
gene id: 395965:MSIL_RS05000
uniprot id: B8EJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

395965:MSIL RS13390
gene id: 395965:MSIL_RS13390
uniprot id: B8EQ61
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS13190
gene id: 395965:MSIL_RS13190
uniprot id: B8EQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

395965:MSIL RS00325
gene id: 395965:MSIL_RS00325
uniprot id: B8EL51
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS16410
gene id: 395965:MSIL_RS16410
uniprot id: B8EQB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

395965:MSIL RS10425
gene id: 395965:MSIL_RS10425
uniprot id: B8EPX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

395965:MSIL RS17650
gene id: 395965:MSIL_RS17650
uniprot id: B8ETL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

395965:MSIL RS05450
gene id: 395965:MSIL_RS05450
uniprot id: B8ELN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

395965:MSIL RS14285
gene id: 395965:MSIL_RS14285
uniprot id: B8ET84
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

395965:MSIL RS08985
gene id: 395965:MSIL_RS08985
uniprot id: B8ELS9
names: Similarity
messages: Belongs to the ArsC family.

395965:MSIL RS04640
gene id: 395965:MSIL_RS04640
uniprot id: B8ESH8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

395965:MSIL RS17565
gene id: 395965:MSIL_RS17565
uniprot id: B8ETJ7
names: Function
names: Similarity
messages: Belongs to the nitrile hydratase subunit beta family.
messages: NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.

395965:MSIL RS13435
gene id: 395965:MSIL_RS13435
uniprot id: B8EQ71
names: Similarity
messages: Belongs to the GcvT family.

395965:MSIL RS04370
gene id: 395965:MSIL_RS04370
uniprot id: B8ESC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

395965:MSIL RS02780
gene id: 395965:MSIL_RS02780
uniprot id: B8ELD0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

395965:MSIL RS15265
gene id: 395965:MSIL_RS15265
uniprot id: B8EIT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

395965:MSIL RS00170
gene id: 395965:MSIL_RS00170
uniprot id: B8EL21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

395965:MSIL RS16140
gene id: 395965:MSIL_RS16140
uniprot id: B8EMF0
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Membrane
messages: Secreted

395965:MSIL RS12705
gene id: 395965:MSIL_RS12705
uniprot id: B8EM29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

395965:MSIL RS16940
gene id: 395965:MSIL_RS16940
uniprot id: B8ES19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

395965:MSIL RS13010
gene id: 395965:MSIL_RS13010
uniprot id: B8EM87
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

395965:MSIL RS00710
gene id: 395965:MSIL_RS00710
uniprot id: B8EMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

395965:MSIL RS00580
gene id: 395965:MSIL_RS00580
uniprot id: B8EL98
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS07240
gene id: 395965:MSIL_RS07240
uniprot id: B8ESP7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS18455
gene id: 395965:MSIL_RS18455
uniprot id: B8EJ26
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS07960
gene id: 395965:MSIL_RS07960
uniprot id: B8EI30
names: Similarity
messages: Belongs to the aspartokinase family.

395965:MSIL RS01385
gene id: 395965:MSIL_RS01385
uniprot id: B8EP10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

395965:MSIL RS16155
gene id: 395965:MSIL_RS16155
uniprot id: B8EMF3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

395965:MSIL RS00630
gene id: 395965:MSIL_RS00630
uniprot id: B8ELA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

395965:MSIL RS14245
gene id: 395965:MSIL_RS14245
uniprot id: B8ET77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

395965:MSIL RS19800
gene id: 395965:MSIL_RS19800
uniprot id: B8EMV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395965:MSIL RS04325
gene id: 395965:MSIL_RS04325
uniprot id: B8ESB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

395965:MSIL RS03375
gene id: 395965:MSIL_RS03375
uniprot id: B8ENC1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

395965:MSIL RS01695
gene id: 395965:MSIL_RS01695
uniprot id: B8EQN8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

395965:MSIL RS17555
gene id: 395965:MSIL_RS17555
uniprot id: B8ETJ5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

395965:MSIL RS18440
gene id: 395965:MSIL_RS18440
uniprot id: B8EJ23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

395965:MSIL RS02130
gene id: 395965:MSIL_RS02130
uniprot id: B8EQX3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

395965:MSIL RS15000
gene id: 395965:MSIL_RS15000
uniprot id: B8EIP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

395965:MSIL RS13265
gene id: 395965:MSIL_RS13265
uniprot id: B8EQ36
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS08200
gene id: 395965:MSIL_RS08200
uniprot id: B8EI75
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

395965:MSIL RS00540
gene id: 395965:MSIL_RS00540
uniprot id: B8EL90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS18320
gene id: 395965:MSIL_RS18320
uniprot id: B8EIZ9
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS14480
gene id: 395965:MSIL_RS14480
uniprot id: B8ETC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

395965:MSIL RS02375
gene id: 395965:MSIL_RS02375
uniprot id: B8EJN6
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS03320
gene id: 395965:MSIL_RS03320
uniprot id: B8ENB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

395965:MSIL RS04200
gene id: 395965:MSIL_RS04200
uniprot id: B8ER39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

395965:MSIL RS02250
gene id: 395965:MSIL_RS02250
uniprot id: B8EJL4
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

395965:MSIL RS08340
gene id: 395965:MSIL_RS08340
uniprot id: B8EK44
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395965:MSIL RS08000
gene id: 395965:MSIL_RS08000
uniprot id: B8EI38
names: Similarity
messages: Belongs to the UPF0145 family.

395965:MSIL RS19095
gene id: 395965:MSIL_RS19095
uniprot id: B8EJF0
names: Similarity
messages: Belongs to the peptidase A31 family.

395965:MSIL RS05995
gene id: 395965:MSIL_RS05995
uniprot id: B8ENK1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS05810
gene id: 395965:MSIL_RS05810
uniprot id: B8ENG5
names: Similarity
messages: Belongs to the peptidase C40 family.

395965:MSIL RS00340
gene id: 395965:MSIL_RS00340
uniprot id: B8EL54
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS00890
gene id: 395965:MSIL_RS00890
uniprot id: B8EN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

395965:MSIL RS10405
gene id: 395965:MSIL_RS10405
uniprot id: B8EPX3
names: Similarity
messages: Belongs to the PucC family.

395965:MSIL RS14375
gene id: 395965:MSIL_RS14375
uniprot id: B8ETA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

395965:MSIL RS18375
gene id: 395965:MSIL_RS18375
uniprot id: B8EJ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

395965:MSIL RS14370
gene id: 395965:MSIL_RS14370
uniprot id: B8ETA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

395965:MSIL RS08110
gene id: 395965:MSIL_RS08110
uniprot id: B8EI59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

395965:MSIL RS06245
gene id: 395965:MSIL_RS06245
uniprot id: B8EPH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

395965:MSIL RS18520
gene id: 395965:MSIL_RS18520
uniprot id: B8EJ39
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.
messages: Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.

395965:MSIL RS03555
gene id: 395965:MSIL_RS03555
uniprot id: B8EP79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395965:MSIL RS15855
gene id: 395965:MSIL_RS15855
uniprot id: B8EKZ3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

395965:MSIL RS12940
gene id: 395965:MSIL_RS12940
uniprot id: B8EM73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

395965:MSIL RS18400
gene id: 395965:MSIL_RS18400
uniprot id: B8EJ15
names: Similarity
messages: Belongs to the HesB/IscA family.

395965:MSIL RS04125
gene id: 395965:MSIL_RS04125
uniprot id: B8ER24
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS04440
gene id: 395965:MSIL_RS04440
uniprot id: B8ESE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS19870
gene id: 395965:MSIL_RS19870
uniprot id: B8EMW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

395965:MSIL RS05115
gene id: 395965:MSIL_RS05115
uniprot id: B8EK13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

395965:MSIL RS17665
gene id: 395965:MSIL_RS17665
uniprot id: B8ETL7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS10250
gene id: 395965:MSIL_RS10250
uniprot id: B8EPU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

395965:MSIL RS03270
gene id: 395965:MSIL_RS03270
uniprot id: B8ENA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

395965:MSIL RS16555
gene id: 395965:MSIL_RS16555
uniprot id: B8EQE6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

395965:MSIL RS03745
gene id: 395965:MSIL_RS03745
uniprot id: B8EPB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

395965:MSIL RS02620
gene id: 395965:MSIL_RS02620
uniprot id: B8EJT3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

395965:MSIL RS03280
gene id: 395965:MSIL_RS03280
uniprot id: B8ENA2
names: Similarity
messages: Belongs to the peptidase S41A family.

395965:MSIL RS19365
gene id: 395965:MSIL_RS19365
uniprot id: B8EML6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

395965:MSIL RS12360
gene id: 395965:MSIL_RS12360
uniprot id: B8EKI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS08440
gene id: 395965:MSIL_RS08440
uniprot id: B8EK64
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

395965:MSIL RS02155
gene id: 395965:MSIL_RS02155
uniprot id: B8EQX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

395965:MSIL RS14410
gene id: 395965:MSIL_RS14410
uniprot id: B8ETA9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS03640
gene id: 395965:MSIL_RS03640
uniprot id: B8EP93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

395965:MSIL RS10895
gene id: 395965:MSIL_RS10895
uniprot id: B8ERM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS17820
gene id: 395965:MSIL_RS17820
uniprot id: B8ETP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS16900
gene id: 395965:MSIL_RS16900
uniprot id: B8EQL5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

395965:MSIL RS02560
gene id: 395965:MSIL_RS02560
uniprot id: B8EJS1
names: Similarity
messages: Belongs to the TrpC family.

395965:MSIL RS18065
gene id: 395965:MSIL_RS18065
uniprot id: B8EIV4
names: Similarity
messages: Belongs to the peptidase C59 family.

395965:MSIL RS19250
gene id: 395965:MSIL_RS19250
uniprot id: B8EJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

395965:MSIL RS14515
gene id: 395965:MSIL_RS14515
uniprot id: B8ETD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

395965:MSIL RS12710
gene id: 395965:MSIL_RS12710
uniprot id: B8EM30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS17295
gene id: 395965:MSIL_RS17295
uniprot id: B8ES87
names: Similarity
messages: Belongs to the DSD1 family.

395965:MSIL RS18050
gene id: 395965:MSIL_RS18050
uniprot id: B8EIV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

395965:MSIL RS05360
gene id: 395965:MSIL_RS05360
uniprot id: B8ELL3
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS04155
gene id: 395965:MSIL_RS04155
uniprot id: B8ER30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS17600
gene id: 395965:MSIL_RS17600
uniprot id: B8ETK5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS17710
gene id: 395965:MSIL_RS17710
uniprot id: B8ETM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

395965:MSIL RS17465
gene id: 395965:MSIL_RS17465
uniprot id: B8ESB6
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

395965:MSIL RS10825
gene id: 395965:MSIL_RS10825
uniprot id: B8ERK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

395965:MSIL RS07520
gene id: 395965:MSIL_RS07520
uniprot id: B8ESU3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

395965:MSIL RS17765
gene id: 395965:MSIL_RS17765
uniprot id: B8ETN8
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

395965:MSIL RS19625
gene id: 395965:MSIL_RS19625
uniprot id: B8EMR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

395965:MSIL RS09250
gene id: 395965:MSIL_RS09250
uniprot id: B8ELX8
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS19275
gene id: 395965:MSIL_RS19275
uniprot id: B8EMJ8
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS12345
gene id: 395965:MSIL_RS12345
uniprot id: B8EKH7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

395965:MSIL RS00465
gene id: 395965:MSIL_RS00465
uniprot id: B8EL77
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

395965:MSIL RS04290
gene id: 395965:MSIL_RS04290
uniprot id: B8ER57
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

395965:MSIL RS18035
gene id: 395965:MSIL_RS18035
uniprot id: B8EIU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

395965:MSIL RS17780
gene id: 395965:MSIL_RS17780
uniprot id: B8ETP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

395965:MSIL RS10430
gene id: 395965:MSIL_RS10430
uniprot id: B8EPX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

395965:MSIL RS05970
gene id: 395965:MSIL_RS05970
uniprot id: B8ENJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

395965:MSIL RS07565
gene id: 395965:MSIL_RS07565
uniprot id: B8ESV2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

395965:MSIL RS05275
gene id: 395965:MSIL_RS05275
uniprot id: B8ELJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

395965:MSIL RS06640
gene id: 395965:MSIL_RS06640
uniprot id: B8ER80
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

395965:MSIL RS02845
gene id: 395965:MSIL_RS02845
uniprot id: B8ELE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

395965:MSIL RS14695
gene id: 395965:MSIL_RS14695
uniprot id: B8ETG5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS07255
gene id: 395965:MSIL_RS07255
uniprot id: B8ESQ0
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS06850
gene id: 395965:MSIL_RS06850
uniprot id: B8ERB9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

395965:MSIL RS02480
gene id: 395965:MSIL_RS02480
uniprot id: B8EJQ6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

395965:MSIL RS18615
gene id: 395965:MSIL_RS18615
uniprot id: B8EJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

395965:MSIL RS17720
gene id: 395965:MSIL_RS17720
uniprot id: B8ETM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

395965:MSIL RS19150
gene id: 395965:MSIL_RS19150
uniprot id: B8EJG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

395965:MSIL RS13485
gene id: 395965:MSIL_RS13485
uniprot id: B8EQ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

395965:MSIL RS11695
gene id: 395965:MSIL_RS11695
uniprot id: B8EIA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS05440
gene id: 395965:MSIL_RS05440
uniprot id: B8ELM8
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS11735
gene id: 395965:MSIL_RS11735
uniprot id: B8EIA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

395965:MSIL RS02830
gene id: 395965:MSIL_RS02830
uniprot id: B8ELD8
names: Similarity
messages: Belongs to the NodU/CmcH family.

395965:MSIL RS19685
gene id: 395965:MSIL_RS19685
uniprot id: B8EMT0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

395965:MSIL RS01450
gene id: 395965:MSIL_RS01450
uniprot id: B8EP23
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

395965:MSIL RS00130
gene id: 395965:MSIL_RS00130
uniprot id: B8EL13
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

395965:MSIL RS09090
gene id: 395965:MSIL_RS09090
uniprot id: B8ELU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

395965:MSIL RS05170
gene id: 395965:MSIL_RS05170
uniprot id: B8EK23
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

395965:MSIL RS04020
gene id: 395965:MSIL_RS04020
uniprot id: B8ER06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

395965:MSIL RS00735
gene id: 395965:MSIL_RS00735
uniprot id: B8EMY9
names: Similarity
messages: Belongs to the peptidase S49 family.

395965:MSIL RS13020
gene id: 395965:MSIL_RS13020
uniprot id: B8EM89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

395965:MSIL RS18275
gene id: 395965:MSIL_RS18275
uniprot id: B8EIZ1
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

395965:MSIL RS03025
gene id: 395965:MSIL_RS03025
uniprot id: B8ELH8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

395965:MSIL RS10940
gene id: 395965:MSIL_RS10940
uniprot id: B8ERM9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

395965:MSIL RS02870
gene id: 395965:MSIL_RS02870
uniprot id: B8ELE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

395965:MSIL RS02165
gene id: 395965:MSIL_RS02165
uniprot id: B8EQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

395965:MSIL RS04780
gene id: 395965:MSIL_RS04780
uniprot id: B8ESK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

395965:MSIL RS07040
gene id: 395965:MSIL_RS07040
uniprot id: B8ERF7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

395965:MSIL RS16045
gene id: 395965:MSIL_RS16045
uniprot id: B8EMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

395965:MSIL RS18285
gene id: 395965:MSIL_RS18285
uniprot id: B8EIZ2
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

395965:MSIL RS09725
gene id: 395965:MSIL_RS09725
uniprot id: B8ENR4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

395965:MSIL RS09880
gene id: 395965:MSIL_RS09880
uniprot id: B8ENU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

395965:MSIL RS02975
gene id: 395965:MSIL_RS02975
uniprot id: B8ELG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

395965:MSIL RS15185
gene id: 395965:MSIL_RS15185
uniprot id: B8EIS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

395965:MSIL RS01815
gene id: 395965:MSIL_RS01815
uniprot id: B8EQR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS17680
gene id: 395965:MSIL_RS17680
uniprot id: B8ETM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

395965:MSIL RS14560
gene id: 395965:MSIL_RS14560
uniprot id: B8ETD9
names: Similarity
messages: Belongs to the peptidase M16 family.

395965:MSIL RS05200
gene id: 395965:MSIL_RS05200
uniprot id: B8EK29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

395965:MSIL RS11185
gene id: 395965:MSIL_RS11185
uniprot id: B8ESY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

395965:MSIL RS11315
gene id: 395965:MSIL_RS11315
uniprot id: B8ET12
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS15100
gene id: 395965:MSIL_RS15100
uniprot id: B8EIQ9
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS05935
gene id: 395965:MSIL_RS05935
uniprot id: B8ENJ0
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

395965:MSIL RS02160
gene id: 395965:MSIL_RS02160
uniprot id: B8EQX9
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

395965:MSIL RS08285
gene id: 395965:MSIL_RS08285
uniprot id: B8EK34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

395965:MSIL RS12295
gene id: 395965:MSIL_RS12295
uniprot id: B8EKG7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS01830
gene id: 395965:MSIL_RS01830
uniprot id: B8EQR6
names: Similarity
messages: Belongs to the MipA/OmpV family.

395965:MSIL RS15270
gene id: 395965:MSIL_RS15270
uniprot id: B8EIT8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

395965:MSIL RS16935
gene id: 395965:MSIL_RS16935
uniprot id: B8ES18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

395965:MSIL RS14795
gene id: 395965:MSIL_RS14795
uniprot id: B8EIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

395965:MSIL RS17745
gene id: 395965:MSIL_RS17745
uniprot id: B8ETN4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

395965:MSIL RS00220
gene id: 395965:MSIL_RS00220
uniprot id: B8EL31
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

395965:MSIL RS01670
gene id: 395965:MSIL_RS01670
uniprot id: B8EQN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

395965:MSIL RS03675
gene id: 395965:MSIL_RS03675
uniprot id: B8EP99
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

395965:MSIL RS09570
gene id: 395965:MSIL_RS09570
uniprot id: B8ENN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395965:MSIL RS19290
gene id: 395965:MSIL_RS19290
uniprot id: B8EMK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

395965:MSIL RS17955
gene id: 395965:MSIL_RS17955
uniprot id: B8ETS2
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

395965:MSIL RS02100
gene id: 395965:MSIL_RS02100
uniprot id: B8EQW7
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS18425
gene id: 395965:MSIL_RS18425
uniprot id: B8EJ20
names: Similarity
messages: Belongs to the NifX/NifY family.

395965:MSIL RS06785
gene id: 395965:MSIL_RS06785
uniprot id: B8ERA7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS02725
gene id: 395965:MSIL_RS02725
uniprot id: B8ELB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

395965:MSIL RS07065
gene id: 395965:MSIL_RS07065
uniprot id: B8ESL1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

395965:MSIL RS01760
gene id: 395965:MSIL_RS01760
uniprot id: B8EQQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

395965:MSIL RS00110
gene id: 395965:MSIL_RS00110
uniprot id: B8EL09
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

395965:MSIL RS08130
gene id: 395965:MSIL_RS08130
uniprot id: B8EI63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

395965:MSIL RS19705
gene id: 395965:MSIL_RS19705
uniprot id: B8EMT4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

395965:MSIL RS05345
gene id: 395965:MSIL_RS05345
uniprot id: B8ELL0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

395965:MSIL RS19380
gene id: 395965:MSIL_RS19380
uniprot id: B8EML9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

395965:MSIL RS06020
gene id: 395965:MSIL_RS06020
uniprot id: B8ENK6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395965:MSIL RS02965
gene id: 395965:MSIL_RS02965
uniprot id: B8ELG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

395965:MSIL RS16835
gene id: 395965:MSIL_RS16835
uniprot id: B8EQK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

395965:MSIL RS08565
gene id: 395965:MSIL_RS08565
uniprot id: B8EK89
names: Similarity
messages: Belongs to the citrate synthase family.

395965:MSIL RS02575
gene id: 395965:MSIL_RS02575
uniprot id: B8EJS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

395965:MSIL RS16450
gene id: 395965:MSIL_RS16450
uniprot id: B8EQC5
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

395965:MSIL RS16490
gene id: 395965:MSIL_RS16490
uniprot id: B8EQD3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395965:MSIL RS05495
gene id: 395965:MSIL_RS05495
uniprot id: B8ELP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

395965:MSIL RS16540
gene id: 395965:MSIL_RS16540
uniprot id: B8EQE4
names: Similarity
messages: Belongs to the RlpA family.

395965:MSIL RS05110
gene id: 395965:MSIL_RS05110
uniprot id: B8EK12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

395965:MSIL RS14315
gene id: 395965:MSIL_RS14315
uniprot id: B8ET90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

395965:MSIL RS13005
gene id: 395965:MSIL_RS13005
uniprot id: B8EM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

395965:MSIL RS17060
gene id: 395965:MSIL_RS17060
uniprot id: B8ES44
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

395965:MSIL RS05040
gene id: 395965:MSIL_RS05040
uniprot id: B8EJZ8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

395965:MSIL RS02580
gene id: 395965:MSIL_RS02580
uniprot id: B8EJS5
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

395965:MSIL RS00550
gene id: 395965:MSIL_RS00550
uniprot id: B8EL92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

395965:MSIL RS19590
gene id: 395965:MSIL_RS19590
uniprot id: B8EMR1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

395965:MSIL RS07390
gene id: 395965:MSIL_RS07390
uniprot id: B8ESS3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

395965:MSIL RS08310
gene id: 395965:MSIL_RS08310
uniprot id: B8EK38
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

395965:MSIL RS17685
gene id: 395965:MSIL_RS17685
uniprot id: B8ETM1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395965:MSIL RS02925
gene id: 395965:MSIL_RS02925
uniprot id: B8ELF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

395965:MSIL RS07035
gene id: 395965:MSIL_RS07035
uniprot id: B8ERF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS04375
gene id: 395965:MSIL_RS04375
uniprot id: B8ESC9
names: Similarity
messages: Belongs to the virb1 family.

395965:MSIL RS06515
gene id: 395965:MSIL_RS06515
uniprot id: B8EPN4
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.
messages: Belongs to the chaperonin (HSP60) family.

395965:MSIL RS20240
gene id: 395965:MSIL_RS20240
uniprot id: B8EQ13
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS07190
gene id: 395965:MSIL_RS07190
uniprot id: B8ESN7
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS02215
gene id: 395965:MSIL_RS02215
uniprot id: B8EJK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

395965:MSIL RS09140
gene id: 395965:MSIL_RS09140
uniprot id: B8ELV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

395965:MSIL RS08455
gene id: 395965:MSIL_RS08455
uniprot id: B8EK67
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

395965:MSIL RS16150
gene id: 395965:MSIL_RS16150
uniprot id: B8EMF2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

395965:MSIL RS04360
gene id: 395965:MSIL_RS04360
uniprot id: B8ESC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

395965:MSIL RS15285
gene id: 395965:MSIL_RS15285
uniprot id: B8EIU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395965:MSIL RS07900
gene id: 395965:MSIL_RS07900
uniprot id: B8EI18
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

395965:MSIL RS06250
gene id: 395965:MSIL_RS06250
uniprot id: B8EPI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

395965:MSIL RS05510
gene id: 395965:MSIL_RS05510
uniprot id: B8ELP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

395965:MSIL RS02900
gene id: 395965:MSIL_RS02900
uniprot id: B8ELF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

395965:MSIL RS15415
gene id: 395965:MSIL_RS15415
uniprot id: B8EKQ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

395965:MSIL RS19145
gene id: 395965:MSIL_RS19145
uniprot id: B8EJG0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

395965:MSIL RS07115
gene id: 395965:MSIL_RS07115
uniprot id: B8ESM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

395965:MSIL RS19400
gene id: 395965:MSIL_RS19400
uniprot id: B8EMM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

395965:MSIL RS16480
gene id: 395965:MSIL_RS16480
uniprot id: B8EQD1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395965:MSIL RS11010
gene id: 395965:MSIL_RS11010
uniprot id: B8ERP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

395965:MSIL RS04975
gene id: 395965:MSIL_RS04975
uniprot id: B8EJY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

395965:MSIL RS11990
gene id: 395965:MSIL_RS11990
uniprot id: B8EIF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

395965:MSIL RS00420
gene id: 395965:MSIL_RS00420
uniprot id: B8EL69
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

395965:MSIL RS17240
gene id: 395965:MSIL_RS17240
uniprot id: B8ES78
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

395965:MSIL RS03385
gene id: 395965:MSIL_RS03385
uniprot id: B8ENC3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

395965:MSIL RS03065
gene id: 395965:MSIL_RS03065
uniprot id: B8EN62
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

395965:MSIL RS06960
gene id: 395965:MSIL_RS06960
uniprot id: B8ERE1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

395965:MSIL RS19045
gene id: 395965:MSIL_RS19045
uniprot id: B8EJE0
names: Similarity
messages: Belongs to the HypE family.

395965:MSIL RS03295
gene id: 395965:MSIL_RS03295
uniprot id: B8ENA5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

395965:MSIL RS13795
gene id: 395965:MSIL_RS13795
uniprot id: B8ERT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

395965:MSIL RS06955
gene id: 395965:MSIL_RS06955
uniprot id: B8ERE0
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS01895
gene id: 395965:MSIL_RS01895
uniprot id: B8EQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

395965:MSIL RS09110
gene id: 395965:MSIL_RS09110
uniprot id: B8ELV1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

395965:MSIL RS07275
gene id: 395965:MSIL_RS07275
uniprot id: B8ESQ4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395965:MSIL RS18120
gene id: 395965:MSIL_RS18120
uniprot id: B8EIW5
names: Similarity
messages: Belongs to the YggT family.

395965:MSIL RS18080
gene id: 395965:MSIL_RS18080
uniprot id: B8EIV7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395965:MSIL RS10730
gene id: 395965:MSIL_RS10730
uniprot id: B8ERI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

395965:MSIL RS12215
gene id: 395965:MSIL_RS12215
uniprot id: B8EIK2
names: Similarity
messages: Belongs to the HisA/HisF family.

395965:MSIL RS14890
gene id: 395965:MSIL_RS14890
uniprot id: B8EIM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395965:MSIL RS17125
gene id: 395965:MSIL_RS17125
uniprot id: B8ES58
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395965:MSIL RS17535
gene id: 395965:MSIL_RS17535
uniprot id: B8ETJ1
names: Subcellular Location Annotation
messages: Membrane

395965:MSIL RS00015
gene id: 395965:MSIL_RS00015
uniprot id: B8EJI4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

395965:MSIL RS19695
gene id: 395965:MSIL_RS19695
uniprot id: B8EMT2
names: Similarity
messages: Belongs to the YkuD family.

395965:MSIL RS10380
gene id: 395965:MSIL_RS10380
uniprot id: B8EPW8
names: Function
names: Similarity
messages: Belongs to the AcsF family.
messages: Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).