395963:BIND RS04215
gene id: 395963:BIND_RS04215
uniprot id: B2IH67
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS12360
gene id: 395963:BIND_RS12360
uniprot id: B2II99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

395963:BIND RS18210
gene id: 395963:BIND_RS18210
uniprot id: B2IG64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

395963:BIND RS14795
gene id: 395963:BIND_RS14795
uniprot id: B2IKW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

395963:BIND RS00745
gene id: 395963:BIND_RS00745
uniprot id: B2IBT2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

395963:BIND RS05935
gene id: 395963:BIND_RS05935
uniprot id: B2IJ48
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS16325
gene id: 395963:BIND_RS16325
uniprot id: B2ID14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

395963:BIND RS17590
gene id: 395963:BIND_RS17590
uniprot id: B2IEL0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

395963:BIND RS07215
gene id: 395963:BIND_RS07215
uniprot id: B2IKM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

395963:BIND RS11665
gene id: 395963:BIND_RS11665
uniprot id: B2IHD5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

395963:BIND RS02415
gene id: 395963:BIND_RS02415
uniprot id: B2IET4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

395963:BIND RS06400
gene id: 395963:BIND_RS06400
uniprot id: B2IJN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Membrane
messages: Transport of potassium into the cell.

395963:BIND RS03835
gene id: 395963:BIND_RS03835
uniprot id: B2IGY7
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

395963:BIND RS09135
gene id: 395963:BIND_RS09135
uniprot id: B2IDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

395963:BIND RS03765
gene id: 395963:BIND_RS03765
uniprot id: B2IGK4
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

395963:BIND RS19320
gene id: 395963:BIND_RS19320
uniprot id: B2ILF1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395963:BIND RS06650
gene id: 395963:BIND_RS06650
uniprot id: B2IK18
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

395963:BIND RS17330
gene id: 395963:BIND_RS17330
uniprot id: B2IEN2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

395963:BIND RS06140
gene id: 395963:BIND_RS06140
uniprot id: B2IJ91
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

395963:BIND RS10750
gene id: 395963:BIND_RS10750
uniprot id: B2IG07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

395963:BIND RS12425
gene id: 395963:BIND_RS12425
uniprot id: B2IIB2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS02655
gene id: 395963:BIND_RS02655
uniprot id: B2IEY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

395963:BIND RS14610
gene id: 395963:BIND_RS14610
uniprot id: B2IKI5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

395963:BIND RS07755
gene id: 395963:BIND_RS07755
uniprot id: B2IB78
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

395963:BIND RS16855
gene id: 395963:BIND_RS16855
uniprot id: B2IDU8
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

395963:BIND RS15400
gene id: 395963:BIND_RS15400
uniprot id: B2IBH7
names: Similarity
messages: Belongs to the peptidase C40 family.

395963:BIND RS02800
gene id: 395963:BIND_RS02800
uniprot id: B2IF11
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS01105
gene id: 395963:BIND_RS01105
uniprot id: B2ICI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

395963:BIND RS02020
gene id: 395963:BIND_RS02020
uniprot id: B2IE27
names: Similarity
messages: Belongs to the HesB/IscA family.

395963:BIND RS17190
gene id: 395963:BIND_RS17190
uniprot id: B2IEK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS07350
gene id: 395963:BIND_RS07350
uniprot id: B2IKP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

395963:BIND RS07010
gene id: 395963:BIND_RS07010
uniprot id: B2IK89
names: Subcellular Location Annotation
messages: Cytoplasm

395963:BIND RS16735
gene id: 395963:BIND_RS16735
uniprot id: B2IDS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

395963:BIND RS12210
gene id: 395963:BIND_RS12210
uniprot id: B2IHY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

395963:BIND RS15945
gene id: 395963:BIND_RS15945
uniprot id: B2ICB5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS00420
gene id: 395963:BIND_RS00420
uniprot id: B2IB43
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS17555
gene id: 395963:BIND_RS17555
uniprot id: B2IES7
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS05160
gene id: 395963:BIND_RS05160
uniprot id: B2II77
names: Similarity
messages: Belongs to the ArsC family.

395963:BIND RS07655
gene id: 395963:BIND_RS07655
uniprot id: B2IB58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

395963:BIND RS19070
gene id: 395963:BIND_RS19070
uniprot id: B2ILA5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

395963:BIND RS11340
gene id: 395963:BIND_RS11340
uniprot id: B2IGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

395963:BIND RS12655
gene id: 395963:BIND_RS12655
uniprot id: B2IIF8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

395963:BIND RS09925
gene id: 395963:BIND_RS09925
uniprot id: B2IEJ1
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

395963:BIND RS18140
gene id: 395963:BIND_RS18140
uniprot id: B2IG51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

395963:BIND RS11855
gene id: 395963:BIND_RS11855
uniprot id: B2IHR5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

395963:BIND RS17320
gene id: 395963:BIND_RS17320
uniprot id: B2IEN0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

395963:BIND RS03515
gene id: 395963:BIND_RS03515
uniprot id: B2IGF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

395963:BIND RS07520
gene id: 395963:BIND_RS07520
uniprot id: B2IKS6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS14760
gene id: 395963:BIND_RS14760
uniprot id: B2IKV4
names: Similarity
messages: Belongs to the TrpF family.

395963:BIND RS00890
gene id: 395963:BIND_RS00890
uniprot id: B2IBW1
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS09185
gene id: 395963:BIND_RS09185
uniprot id: B2IDK6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

395963:BIND RS17145
gene id: 395963:BIND_RS17145
uniprot id: B2IEJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

395963:BIND RS03735
gene id: 395963:BIND_RS03735
uniprot id: B2IGJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

395963:BIND RS06955
gene id: 395963:BIND_RS06955
uniprot id: B2IK78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

395963:BIND RS00210
gene id: 395963:BIND_RS00210
uniprot id: B2IB00
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

395963:BIND RS01815
gene id: 395963:BIND_RS01815
uniprot id: B2IDG0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS01005
gene id: 395963:BIND_RS01005
uniprot id: B2ICG8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

395963:BIND RS05845
gene id: 395963:BIND_RS05845
uniprot id: B2IJ30
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

395963:BIND RS17625
gene id: 395963:BIND_RS17625
uniprot id: B2IFC5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

395963:BIND RS01620
gene id: 395963:BIND_RS01620
uniprot id: B2IDB5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

395963:BIND RS18480
gene id: 395963:BIND_RS18480
uniprot id: B2IGB3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

395963:BIND RS07800
gene id: 395963:BIND_RS07800
uniprot id: B2IB87
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

395963:BIND RS08035
gene id: 395963:BIND_RS08035
uniprot id: B2IBD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

395963:BIND RS02120
gene id: 395963:BIND_RS02120
uniprot id: B2IE47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

395963:BIND RS19940
gene id: 395963:BIND_RS19940
uniprot id: B2IE70
names: Similarity
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.

395963:BIND RS00235
gene id: 395963:BIND_RS00235
uniprot id: B2IB06
names: Cofactor
messages: Can also use Mn(2+) ion.

395963:BIND RS02395
gene id: 395963:BIND_RS02395
uniprot id: B2IET0
names: Similarity
messages: Belongs to the ArsC family.

395963:BIND RS12040
gene id: 395963:BIND_RS12040
uniprot id: B2IHV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395963:BIND RS04465
gene id: 395963:BIND_RS04465
uniprot id: B2IHK6
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

395963:BIND RS18620
gene id: 395963:BIND_RS18620
uniprot id: B2IGW8
names: Similarity
messages: Belongs to the SCO1/2 family.

395963:BIND RS11840
gene id: 395963:BIND_RS11840
uniprot id: B2IHR2
names: Similarity
messages: Belongs to the UPF0303 family.

395963:BIND RS13870
gene id: 395963:BIND_RS13870
uniprot id: B2IJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS18590
gene id: 395963:BIND_RS18590
uniprot id: B2IGW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.

395963:BIND RS12340
gene id: 395963:BIND_RS12340
uniprot id: B2II95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

395963:BIND RS06855
gene id: 395963:BIND_RS06855
uniprot id: B2IK58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

395963:BIND RS06875
gene id: 395963:BIND_RS06875
uniprot id: B2IK62
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

395963:BIND RS06255
gene id: 395963:BIND_RS06255
uniprot id: B2IJJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

395963:BIND RS06800
gene id: 395963:BIND_RS06800
uniprot id: B2IK46
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

395963:BIND RS04340
gene id: 395963:BIND_RS04340
uniprot id: B2IHI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

395963:BIND RS14310
gene id: 395963:BIND_RS14310
uniprot id: B2IBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

395963:BIND RS07640
gene id: 395963:BIND_RS07640
uniprot id: B2IB55
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

395963:BIND RS12265
gene id: 395963:BIND_RS12265
uniprot id: B2IHZ1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

395963:BIND RS14275
gene id: 395963:BIND_RS14275
uniprot id: B2IKB9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

395963:BIND RS04210
gene id: 395963:BIND_RS04210
uniprot id: B2IH66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

395963:BIND RS18075
gene id: 395963:BIND_RS18075
uniprot id: B2IG38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

395963:BIND RS17345
gene id: 395963:BIND_RS17345
uniprot id: B2IEN5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

395963:BIND RS16790
gene id: 395963:BIND_RS16790
uniprot id: B2IDT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

395963:BIND RS19290
gene id: 395963:BIND_RS19290
uniprot id: B2ILE3
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

395963:BIND RS09750
gene id: 395963:BIND_RS09750
uniprot id: B2IEF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

395963:BIND RS05365
gene id: 395963:BIND_RS05365
uniprot id: B2IIK6
names: Similarity
messages: Belongs to the PhoH family.

395963:BIND RS11680
gene id: 395963:BIND_RS11680
uniprot id: B2IHD8
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS02885
gene id: 395963:BIND_RS02885
uniprot id: B2IFK8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

395963:BIND RS01825
gene id: 395963:BIND_RS01825
uniprot id: B2IDG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS11300
gene id: 395963:BIND_RS11300
uniprot id: B2IGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

395963:BIND RS16200
gene id: 395963:BIND_RS16200
uniprot id: B2ICZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

395963:BIND RS19365
gene id: 395963:BIND_RS19365
uniprot id: B2ILF6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

395963:BIND RS09895
gene id: 395963:BIND_RS09895
uniprot id: B2IEI0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

395963:BIND RS14270
gene id: 395963:BIND_RS14270
uniprot id: B2IKB8
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

395963:BIND RS19145
gene id: 395963:BIND_RS19145
uniprot id: B2ILC1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

395963:BIND RS04145
gene id: 395963:BIND_RS04145
uniprot id: B2IH51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS03580
gene id: 395963:BIND_RS03580
uniprot id: B2IGG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

395963:BIND RS00290
gene id: 395963:BIND_RS00290
uniprot id: B2IB17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

395963:BIND RS09455
gene id: 395963:BIND_RS09455
uniprot id: B2IDQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

395963:BIND RS05035
gene id: 395963:BIND_RS05035
uniprot id: B2II53
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

395963:BIND RS17975
gene id: 395963:BIND_RS17975
uniprot id: B2IFJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

395963:BIND RS17970
gene id: 395963:BIND_RS17970
uniprot id: B2IFJ5
names: Subcellular Location Annotation
messages: Mitochondrion

395963:BIND RS17300
gene id: 395963:BIND_RS17300
uniprot id: B2IEM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

395963:BIND RS16840
gene id: 395963:BIND_RS16840
uniprot id: B2IDU5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

395963:BIND RS09460
gene id: 395963:BIND_RS09460
uniprot id: B2IDQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

395963:BIND RS13200
gene id: 395963:BIND_RS13200
uniprot id: B2IIZ2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395963:BIND RS17515
gene id: 395963:BIND_RS17515
uniprot id: B2IER8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

395963:BIND RS11610
gene id: 395963:BIND_RS11610
uniprot id: B2IHC5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

395963:BIND RS10695
gene id: 395963:BIND_RS10695
uniprot id: B2IFZ7
names: Similarity
messages: Belongs to the pirin family.

395963:BIND RS10435
gene id: 395963:BIND_RS10435
uniprot id: B2IFU9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

395963:BIND RS04400
gene id: 395963:BIND_RS04400
uniprot id: B2IHJ4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

395963:BIND RS09510
gene id: 395963:BIND_RS09510
uniprot id: B2IEA5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

395963:BIND RS00650
gene id: 395963:BIND_RS00650
uniprot id: B2IBR4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

395963:BIND RS08005
gene id: 395963:BIND_RS08005
uniprot id: B2IBC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS12440
gene id: 395963:BIND_RS12440
uniprot id: B2IIB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS09980
gene id: 395963:BIND_RS09980
uniprot id: B2IF30
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS19795
gene id: 395963:BIND_RS19795
uniprot id: B2ILN1
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

395963:BIND RS14180
gene id: 395963:BIND_RS14180
uniprot id: B2IK06
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

395963:BIND RS05330
gene id: 395963:BIND_RS05330
uniprot id: B2IIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

395963:BIND RS07245
gene id: 395963:BIND_RS07245
uniprot id: B2IKM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS11935
gene id: 395963:BIND_RS11935
uniprot id: B2IHT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

395963:BIND RS00860
gene id: 395963:BIND_RS00860
uniprot id: B2IBV5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

395963:BIND RS13050
gene id: 395963:BIND_RS13050
uniprot id: B2IIW8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS09280
gene id: 395963:BIND_RS09280
uniprot id: B2IDM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS03405
gene id: 395963:BIND_RS03405
uniprot id: B2IGC7
names: Subcellular Location Annotation
messages: Cytoplasm

395963:BIND RS15425
gene id: 395963:BIND_RS15425
uniprot id: B2IBI1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

395963:BIND RS09885
gene id: 395963:BIND_RS09885
uniprot id: B2IEH8
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS05135
gene id: 395963:BIND_RS05135
uniprot id: B2II73
names: Similarity
messages: Belongs to the GARS family.

395963:BIND RS18205
gene id: 395963:BIND_RS18205
uniprot id: B2IG63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

395963:BIND RS06915
gene id: 395963:BIND_RS06915
uniprot id: B2IK70
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

395963:BIND RS16800
gene id: 395963:BIND_RS16800
uniprot id: B2IDT7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

395963:BIND RS10595
gene id: 395963:BIND_RS10595
uniprot id: B2IFX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

395963:BIND RS01245
gene id: 395963:BIND_RS01245
uniprot id: B2ICL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

395963:BIND RS16605
gene id: 395963:BIND_RS16605
uniprot id: B2ID67
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

395963:BIND RS07975
gene id: 395963:BIND_RS07975
uniprot id: B2IBC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

395963:BIND RS06930
gene id: 395963:BIND_RS06930
uniprot id: B2IK73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

395963:BIND RS02330
gene id: 395963:BIND_RS02330
uniprot id: B2IE87
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS07150
gene id: 395963:BIND_RS07150
uniprot id: B2IKK9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS17835
gene id: 395963:BIND_RS17835
uniprot id: B2IFG6
names: Similarity
messages: Belongs to the CobH/CbiC family.

395963:BIND RS14025
gene id: 395963:BIND_RS14025
uniprot id: B2IJX7
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

395963:BIND RS10295
gene id: 395963:BIND_RS10295
uniprot id: B2IF96
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

395963:BIND RS00315
gene id: 395963:BIND_RS00315
uniprot id: B2IB22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

395963:BIND RS06825
gene id: 395963:BIND_RS06825
uniprot id: B2IK52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

395963:BIND RS07725
gene id: 395963:BIND_RS07725
uniprot id: B2IB72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395963:BIND RS17920
gene id: 395963:BIND_RS17920
uniprot id: B2IFI7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395963:BIND RS09265
gene id: 395963:BIND_RS09265
uniprot id: B2IDM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS20210
gene id: 395963:BIND_RS20210
uniprot id: B2IJC7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

395963:BIND RS02535
gene id: 395963:BIND_RS02535
uniprot id: B2IEW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

395963:BIND RS15125
gene id: 395963:BIND_RS15125
uniprot id: B2IL19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

395963:BIND RS08965
gene id: 395963:BIND_RS08965
uniprot id: B2ICX7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395963:BIND RS06160
gene id: 395963:BIND_RS06160
uniprot id: B2IJ88
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS11400
gene id: 395963:BIND_RS11400
uniprot id: B2IH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

395963:BIND RS02155
gene id: 395963:BIND_RS02155
uniprot id: B2IE54
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

395963:BIND RS06845
gene id: 395963:BIND_RS06845
uniprot id: B2IK56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

395963:BIND RS06525
gene id: 395963:BIND_RS06525
uniprot id: B2IJQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

395963:BIND RS14965
gene id: 395963:BIND_RS14965
uniprot id: B2IKZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS11040
gene id: 395963:BIND_RS11040
uniprot id: B2IGP2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

395963:BIND RS15325
gene id: 395963:BIND_RS15325
uniprot id: B2IBG3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

395963:BIND RS06520
gene id: 395963:BIND_RS06520
uniprot id: B2IJQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

395963:BIND RS12800
gene id: 395963:BIND_RS12800
uniprot id: B2IIS4
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

395963:BIND RS16910
gene id: 395963:BIND_RS16910
uniprot id: B2IDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm

395963:BIND RS14710
gene id: 395963:BIND_RS14710
uniprot id: B2IKK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

395963:BIND RS09805
gene id: 395963:BIND_RS09805
uniprot id: B2IEG2
names: Similarity
messages: Belongs to the pirin family.

395963:BIND RS01055
gene id: 395963:BIND_RS01055
uniprot id: B2ICH7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

395963:BIND RS11165
gene id: 395963:BIND_RS11165
uniprot id: B2IGR4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

395963:BIND RS15370
gene id: 395963:BIND_RS15370
uniprot id: B2IBH1
names: Subcellular Location Annotation
messages: Cytoplasm

395963:BIND RS16985
gene id: 395963:BIND_RS16985
uniprot id: B2IDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS12110
gene id: 395963:BIND_RS12110
uniprot id: B2IHW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395963:BIND RS14755
gene id: 395963:BIND_RS14755
uniprot id: B2IKV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

395963:BIND RS07670
gene id: 395963:BIND_RS07670
uniprot id: B2IB61
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

395963:BIND RS08130
gene id: 395963:BIND_RS08130
uniprot id: B2IBX8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

395963:BIND RS02255
gene id: 395963:BIND_RS02255
uniprot id: B2IE73
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

395963:BIND RS12830
gene id: 395963:BIND_RS12830
uniprot id: B2IIT0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS03180
gene id: 395963:BIND_RS03180
uniprot id: B2IFQ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

395963:BIND RS18300
gene id: 395963:BIND_RS18300
uniprot id: B2IG81
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

395963:BIND RS10390
gene id: 395963:BIND_RS10390
uniprot id: B2IFB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS08645
gene id: 395963:BIND_RS08645
uniprot id: B2ICR2
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS05975
gene id: 395963:BIND_RS05975
uniprot id: B2IJ56
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS05885
gene id: 395963:BIND_RS05885
uniprot id: B2IJ38
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

395963:BIND RS18855
gene id: 395963:BIND_RS18855
uniprot id: B2IL60
names: Caution
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395963:BIND RS08105
gene id: 395963:BIND_RS08105
uniprot id: B2IBX3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS17225
gene id: 395963:BIND_RS17225
uniprot id: B2IEK9
names: Similarity
messages: Belongs to the TmoD/XamoD family.

395963:BIND RS19715
gene id: 395963:BIND_RS19715
uniprot id: B2ILL6
names: Similarity
messages: Belongs to the ParB family.

395963:BIND RS06660
gene id: 395963:BIND_RS06660
uniprot id: B2IK20
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

395963:BIND RS00910
gene id: 395963:BIND_RS00910
uniprot id: B2IBW5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

395963:BIND RS03565
gene id: 395963:BIND_RS03565
uniprot id: B2IGG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

395963:BIND RS05900
gene id: 395963:BIND_RS05900
uniprot id: B2IJ41
names: Similarity
messages: Belongs to the HupF/HypC family.

395963:BIND RS06710
gene id: 395963:BIND_RS06710
uniprot id: B2IK30
names: Similarity
messages: Belongs to the acylphosphatase family.

395963:BIND RS13535
gene id: 395963:BIND_RS13535
uniprot id: B2IJE3
names: Similarity
messages: Belongs to the virb1 family.

395963:BIND RS09105
gene id: 395963:BIND_RS09105
uniprot id: B2IDI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS07040
gene id: 395963:BIND_RS07040
uniprot id: B2IK95
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

395963:BIND RS05820
gene id: 395963:BIND_RS05820
uniprot id: B2IJ25
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

395963:BIND RS00980
gene id: 395963:BIND_RS00980
uniprot id: B2ICG4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

395963:BIND RS02585
gene id: 395963:BIND_RS02585
uniprot id: B2IEX0
names: Similarity
messages: Belongs to the peptidase A31 family.

395963:BIND RS13620
gene id: 395963:BIND_RS13620
uniprot id: B2IJG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

395963:BIND RS02045
gene id: 395963:BIND_RS02045
uniprot id: B2IE32
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

395963:BIND RS13875
gene id: 395963:BIND_RS13875
uniprot id: B2IJU7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

395963:BIND RS10840
gene id: 395963:BIND_RS10840
uniprot id: B2IG25
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS01085
gene id: 395963:BIND_RS01085
uniprot id: B2ICI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

395963:BIND RS07275
gene id: 395963:BIND_RS07275
uniprot id: B2IKN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

395963:BIND RS10650
gene id: 395963:BIND_RS10650
uniprot id: B2IFY8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

395963:BIND RS03350
gene id: 395963:BIND_RS03350
uniprot id: B2IFU0
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS11010
gene id: 395963:BIND_RS11010
uniprot id: B2IGN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.

395963:BIND RS14210
gene id: 395963:BIND_RS14210
uniprot id: B2IK15
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS18800
gene id: 395963:BIND_RS18800
uniprot id: B2IL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

395963:BIND RS17425
gene id: 395963:BIND_RS17425
uniprot id: B2IEQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

395963:BIND RS07370
gene id: 395963:BIND_RS07370
uniprot id: B2IKQ2
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

395963:BIND RS00905
gene id: 395963:BIND_RS00905
uniprot id: B2IBW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

395963:BIND RS01925
gene id: 395963:BIND_RS01925
uniprot id: B2IE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

395963:BIND RS08385
gene id: 395963:BIND_RS08385
uniprot id: B2IC30
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

395963:BIND RS06670
gene id: 395963:BIND_RS06670
uniprot id: B2IK22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

395963:BIND RS14045
gene id: 395963:BIND_RS14045
uniprot id: B2IJX9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS11380
gene id: 395963:BIND_RS11380
uniprot id: B2IH83
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

395963:BIND RS04180
gene id: 395963:BIND_RS04180
uniprot id: B2IH59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

395963:BIND RS14780
gene id: 395963:BIND_RS14780
uniprot id: B2IKV8
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

395963:BIND RS19035
gene id: 395963:BIND_RS19035
uniprot id: B2ILA1
names: Similarity
messages: Belongs to the peptidase S24 family.

395963:BIND RS06240
gene id: 395963:BIND_RS06240
uniprot id: B2IJJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

395963:BIND RS03385
gene id: 395963:BIND_RS03385
uniprot id: B2IGC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

395963:BIND RS07790
gene id: 395963:BIND_RS07790
uniprot id: B2IB85
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

395963:BIND RS15800
gene id: 395963:BIND_RS15800
uniprot id: B2IC85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

395963:BIND RS07710
gene id: 395963:BIND_RS07710
uniprot id: B2IB69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

395963:BIND RS08780
gene id: 395963:BIND_RS08780
uniprot id: B2ICT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

395963:BIND RS14615
gene id: 395963:BIND_RS14615
uniprot id: B2IKI6
names: Similarity
messages: Belongs to the UPF0758 family.

395963:BIND RS02685
gene id: 395963:BIND_RS02685
uniprot id: B2IEY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

395963:BIND RS04130
gene id: 395963:BIND_RS04130
uniprot id: B2IH48
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

395963:BIND RS10015
gene id: 395963:BIND_RS10015
uniprot id: B2IF37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

395963:BIND RS02745
gene id: 395963:BIND_RS02745
uniprot id: B2IF00
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

395963:BIND RS00655
gene id: 395963:BIND_RS00655
uniprot id: B2IBR5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

395963:BIND RS18755
gene id: 395963:BIND_RS18755
uniprot id: B2IL39
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

395963:BIND RS18055
gene id: 395963:BIND_RS18055
uniprot id: B2IG34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

395963:BIND RS00530
gene id: 395963:BIND_RS00530
uniprot id: B2IBP1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS02305
gene id: 395963:BIND_RS02305
uniprot id: B2IE82
names: Similarity
messages: Belongs to the YkuD family.

395963:BIND RS12490
gene id: 395963:BIND_RS12490
uniprot id: B2IIC5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS03915
gene id: 395963:BIND_RS03915
uniprot id: B2IH04
names: Similarity
messages: Belongs to the WrbA family.

395963:BIND RS06630
gene id: 395963:BIND_RS06630
uniprot id: B2IJK6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395963:BIND RS13145
gene id: 395963:BIND_RS13145
uniprot id: B2IIY3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

395963:BIND RS17875
gene id: 395963:BIND_RS17875
uniprot id: B2IFH4
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

395963:BIND RS08815
gene id: 395963:BIND_RS08815
uniprot id: B2ICU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

395963:BIND RS01190
gene id: 395963:BIND_RS01190
uniprot id: B2ICK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

395963:BIND RS13780
gene id: 395963:BIND_RS13780
uniprot id: B2IJS9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

395963:BIND RS13600
gene id: 395963:BIND_RS13600
uniprot id: B2IJF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

395963:BIND RS03715
gene id: 395963:BIND_RS03715
uniprot id: B2IGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

395963:BIND RS15825
gene id: 395963:BIND_RS15825
uniprot id: B2IC90
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

395963:BIND RS16700
gene id: 395963:BIND_RS16700
uniprot id: B2IDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

395963:BIND RS03205
gene id: 395963:BIND_RS03205
uniprot id: B2IFR1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

395963:BIND RS00100
gene id: 395963:BIND_RS00100
uniprot id: B2IAX8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

395963:BIND RS18575
gene id: 395963:BIND_RS18575
uniprot id: B2IGV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

395963:BIND RS03805
gene id: 395963:BIND_RS03805
uniprot id: B2IGE6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

395963:BIND RS18520
gene id: 395963:BIND_RS18520
uniprot id: B2IGB7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

395963:BIND RS16460
gene id: 395963:BIND_RS16460
uniprot id: B2ID39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS12615
gene id: 395963:BIND_RS12615
uniprot id: B2IIF0
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

395963:BIND RS05105
gene id: 395963:BIND_RS05105
uniprot id: B2II67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

395963:BIND RS06375
gene id: 395963:BIND_RS06375
uniprot id: B2IJM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

395963:BIND RS00770
gene id: 395963:BIND_RS00770
uniprot id: B2IBT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

395963:BIND RS18150
gene id: 395963:BIND_RS18150
uniprot id: B2IG53
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

395963:BIND RS11055
gene id: 395963:BIND_RS11055
uniprot id: B2IGP4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

395963:BIND RS14155
gene id: 395963:BIND_RS14155
uniprot id: B2IK01
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

395963:BIND RS16580
gene id: 395963:BIND_RS16580
uniprot id: B2ID62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS12995
gene id: 395963:BIND_RS12995
uniprot id: B2IIV9
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

395963:BIND RS17790
gene id: 395963:BIND_RS17790
uniprot id: B2IFF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

395963:BIND RS04390
gene id: 395963:BIND_RS04390
uniprot id: B2IHJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS15430
gene id: 395963:BIND_RS15430
uniprot id: B2IBI2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

395963:BIND RS03555
gene id: 395963:BIND_RS03555
uniprot id: B2IGG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS18330
gene id: 395963:BIND_RS18330
uniprot id: B2IG85
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

395963:BIND RS12825
gene id: 395963:BIND_RS12825
uniprot id: B2IIS9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395963:BIND RS12235
gene id: 395963:BIND_RS12235
uniprot id: B2IHY6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

395963:BIND RS06895
gene id: 395963:BIND_RS06895
uniprot id: B2IK66
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

395963:BIND RS08720
gene id: 395963:BIND_RS08720
uniprot id: B2ICS6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

395963:BIND RS15885
gene id: 395963:BIND_RS15885
uniprot id: B2ICA3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

395963:BIND RS09840
gene id: 395963:BIND_RS09840
uniprot id: B2IEG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

395963:BIND RS09890
gene id: 395963:BIND_RS09890
uniprot id: B2IEH9
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS05100
gene id: 395963:BIND_RS05100
uniprot id: B2II66
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395963:BIND RS00505
gene id: 395963:BIND_RS00505
uniprot id: B2IBN6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

395963:BIND RS02060
gene id: 395963:BIND_RS02060
uniprot id: B2IE35
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

395963:BIND RS15890
gene id: 395963:BIND_RS15890
uniprot id: B2ICA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

395963:BIND RS10145
gene id: 395963:BIND_RS10145
uniprot id: B2IF64
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS10070
gene id: 395963:BIND_RS10070
uniprot id: B2IF48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

395963:BIND RS01600
gene id: 395963:BIND_RS01600
uniprot id: B2IDB1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

395963:BIND RS17370
gene id: 395963:BIND_RS17370
uniprot id: B2IEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

395963:BIND RS02420
gene id: 395963:BIND_RS02420
uniprot id: B2IET5
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

395963:BIND RS21860
gene id: 395963:BIND_RS21860
uniprot id: B2IBS7
names: Similarity
messages: Belongs to the YkuD family.

395963:BIND RS18470
gene id: 395963:BIND_RS18470
uniprot id: B2IGB1
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

395963:BIND RS15315
gene id: 395963:BIND_RS15315
uniprot id: B2IBG1
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS02210
gene id: 395963:BIND_RS02210
uniprot id: B2IE64
names: Similarity
messages: Belongs to the UDPGP type 2 family.

395963:BIND RS13700
gene id: 395963:BIND_RS13700
uniprot id: B2IJH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

395963:BIND RS06310
gene id: 395963:BIND_RS06310
uniprot id: B2IJL2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

395963:BIND RS12045
gene id: 395963:BIND_RS12045
uniprot id: B2IHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

395963:BIND RS09745
gene id: 395963:BIND_RS09745
uniprot id: B2IEF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

395963:BIND RS05395
gene id: 395963:BIND_RS05395
uniprot id: B2IIL3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS17655
gene id: 395963:BIND_RS17655
uniprot id: B2IFD1
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS15395
gene id: 395963:BIND_RS15395
uniprot id: B2IBH6
names: Similarity
messages: Belongs to the peptidase M17 family.

395963:BIND RS07360
gene id: 395963:BIND_RS07360
uniprot id: B2IKQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

395963:BIND RS06530
gene id: 395963:BIND_RS06530
uniprot id: B2IJQ6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

395963:BIND RS01820
gene id: 395963:BIND_RS01820
uniprot id: B2IDG1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

395963:BIND RS11245
gene id: 395963:BIND_RS11245
uniprot id: B2IGT0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

395963:BIND RS07135
gene id: 395963:BIND_RS07135
uniprot id: B2IKK6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

395963:BIND RS11120
gene id: 395963:BIND_RS11120
uniprot id: B2IGQ6
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

395963:BIND RS12970
gene id: 395963:BIND_RS12970
uniprot id: B2IIV6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

395963:BIND RS06810
gene id: 395963:BIND_RS06810
uniprot id: B2IK49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

395963:BIND RS15520
gene id: 395963:BIND_RS15520
uniprot id: B2IBK0
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

395963:BIND RS18285
gene id: 395963:BIND_RS18285
uniprot id: B2IG78
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

395963:BIND RS15500
gene id: 395963:BIND_RS15500
uniprot id: B2IBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

395963:BIND RS00525
gene id: 395963:BIND_RS00525
uniprot id: B2IBP0
names: Similarity
messages: Belongs to the HesB/IscA family.

395963:BIND RS14660
gene id: 395963:BIND_RS14660
uniprot id: B2IKJ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

395963:BIND RS05320
gene id: 395963:BIND_RS05320
uniprot id: B2IIJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

395963:BIND RS02360
gene id: 395963:BIND_RS02360
uniprot id: B2IE97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

395963:BIND RS05695
gene id: 395963:BIND_RS05695
uniprot id: B2IJ02
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

395963:BIND RS12895
gene id: 395963:BIND_RS12895
uniprot id: B2IIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395963:BIND RS00150
gene id: 395963:BIND_RS00150
uniprot id: B2IAY8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS03780
gene id: 395963:BIND_RS03780
uniprot id: B2IGK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

395963:BIND RS16890
gene id: 395963:BIND_RS16890
uniprot id: B2IDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

395963:BIND RS14825
gene id: 395963:BIND_RS14825
uniprot id: B2IKW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

395963:BIND RS09515
gene id: 395963:BIND_RS09515
uniprot id: B2IEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS04160
gene id: 395963:BIND_RS04160
uniprot id: B2IH55
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

395963:BIND RS04545
gene id: 395963:BIND_RS04545
uniprot id: B2IHM1
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

395963:BIND RS09125
gene id: 395963:BIND_RS09125
uniprot id: B2IDJ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS09430
gene id: 395963:BIND_RS09430
uniprot id: B2IDQ2
names: Similarity
messages: Belongs to the pyruvate kinase family.

395963:BIND RS13630
gene id: 395963:BIND_RS13630
uniprot id: B2IJG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

395963:BIND RS08485
gene id: 395963:BIND_RS08485
uniprot id: B2IC50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

395963:BIND RS06980
gene id: 395963:BIND_RS06980
uniprot id: B2IK83
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

395963:BIND RS06440
gene id: 395963:BIND_RS06440
uniprot id: B2IJN9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

395963:BIND RS05600
gene id: 395963:BIND_RS05600
uniprot id: B2IIQ2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

395963:BIND RS11660
gene id: 395963:BIND_RS11660
uniprot id: B2IHD4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

395963:BIND RS14460
gene id: 395963:BIND_RS14460
uniprot id: B2IKF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS12450
gene id: 395963:BIND_RS12450
uniprot id: B2IIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS06225
gene id: 395963:BIND_RS06225
uniprot id: B2IJJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS11600
gene id: 395963:BIND_RS11600
uniprot id: B2IHC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

395963:BIND RS05495
gene id: 395963:BIND_RS05495
uniprot id: B2IIN3
names: Similarity
messages: Belongs to the creatininase superfamily.

395963:BIND RS15815
gene id: 395963:BIND_RS15815
uniprot id: B2IC88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

395963:BIND RS02925
gene id: 395963:BIND_RS02925
uniprot id: B2IFL6
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS15350
gene id: 395963:BIND_RS15350
uniprot id: B2IBG7
names: Similarity
messages: Belongs to the glutamate synthase family.

395963:BIND RS02445
gene id: 395963:BIND_RS02445
uniprot id: B2IEU0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

395963:BIND RS17595
gene id: 395963:BIND_RS17595
uniprot id: B2IEL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

395963:BIND RS01080
gene id: 395963:BIND_RS01080
uniprot id: B2ICI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

395963:BIND RS14145
gene id: 395963:BIND_RS14145
uniprot id: B2IJZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

395963:BIND RS17540
gene id: 395963:BIND_RS17540
uniprot id: B2IES4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

395963:BIND RS04605
gene id: 395963:BIND_RS04605
uniprot id: B2IHN4
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

395963:BIND RS06805
gene id: 395963:BIND_RS06805
uniprot id: B2IK47
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

395963:BIND RS04635
gene id: 395963:BIND_RS04635
uniprot id: B2IHP0
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS05985
gene id: 395963:BIND_RS05985
uniprot id: B2IJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

395963:BIND RS18290
gene id: 395963:BIND_RS18290
uniprot id: B2IG79
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

395963:BIND RS01800
gene id: 395963:BIND_RS01800
uniprot id: B2IDF7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

395963:BIND RS17275
gene id: 395963:BIND_RS17275
uniprot id: B2IEM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS11625
gene id: 395963:BIND_RS11625
uniprot id: B2IHC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

395963:BIND RS19765
gene id: 395963:BIND_RS19765
uniprot id: B2ILM5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

395963:BIND RS11645
gene id: 395963:BIND_RS11645
uniprot id: B2IHD1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

395963:BIND RS11800
gene id: 395963:BIND_RS11800
uniprot id: B2IHG2
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

395963:BIND RS05225
gene id: 395963:BIND_RS05225
uniprot id: B2IIH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

395963:BIND RS01200
gene id: 395963:BIND_RS01200
uniprot id: B2ICK7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

395963:BIND RS03400
gene id: 395963:BIND_RS03400
uniprot id: B2IGC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

395963:BIND RS12460
gene id: 395963:BIND_RS12460
uniprot id: B2IIB9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

395963:BIND RS15695
gene id: 395963:BIND_RS15695
uniprot id: B2IC63
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

395963:BIND RS06835
gene id: 395963:BIND_RS06835
uniprot id: B2IK54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

395963:BIND RS03945
gene id: 395963:BIND_RS03945
uniprot id: B2IH10
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395963:BIND RS02810
gene id: 395963:BIND_RS02810
uniprot id: B2IF13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS13140
gene id: 395963:BIND_RS13140
uniprot id: B2IIY2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

395963:BIND RS17605
gene id: 395963:BIND_RS17605
uniprot id: B2IFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS01685
gene id: 395963:BIND_RS01685
uniprot id: B2IDD4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

395963:BIND RS06405
gene id: 395963:BIND_RS06405
uniprot id: B2IJN2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

395963:BIND RS02425
gene id: 395963:BIND_RS02425
uniprot id: B2IET6
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

395963:BIND RS03095
gene id: 395963:BIND_RS03095
uniprot id: B2IFP5
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

395963:BIND RS12890
gene id: 395963:BIND_RS12890
uniprot id: B2IIU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395963:BIND RS09570
gene id: 395963:BIND_RS09570
uniprot id: B2IEB7
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

395963:BIND RS06550
gene id: 395963:BIND_RS06550
uniprot id: B2IJR1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS08895
gene id: 395963:BIND_RS08895
uniprot id: B2ICW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

395963:BIND RS18410
gene id: 395963:BIND_RS18410
uniprot id: B2IG99
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

395963:BIND RS07120
gene id: 395963:BIND_RS07120
uniprot id: B2IKA7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

395963:BIND RS05375
gene id: 395963:BIND_RS05375
uniprot id: B2IIK8
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

395963:BIND RS02755
gene id: 395963:BIND_RS02755
uniprot id: B2IF02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

395963:BIND RS05850
gene id: 395963:BIND_RS05850
uniprot id: B2IJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

395963:BIND RS01335
gene id: 395963:BIND_RS01335
uniprot id: B2ICN2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

395963:BIND RS03335
gene id: 395963:BIND_RS03335
uniprot id: B2IFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395963:BIND RS14775
gene id: 395963:BIND_RS14775
uniprot id: B2IKV7
names: Similarity
messages: Belongs to the peptidase S49 family.

395963:BIND RS17730
gene id: 395963:BIND_RS17730
uniprot id: B2IFE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

395963:BIND RS08320
gene id: 395963:BIND_RS08320
uniprot id: B2IC17
names: Similarity
messages: Belongs to the SufE family.

395963:BIND RS04190
gene id: 395963:BIND_RS04190
uniprot id: B2IH61
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

395963:BIND RS09180
gene id: 395963:BIND_RS09180
uniprot id: B2IDK5
names: Similarity
messages: Belongs to the TlyA family.

395963:BIND RS18340
gene id: 395963:BIND_RS18340
uniprot id: B2IG87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

395963:BIND RS17355
gene id: 395963:BIND_RS17355
uniprot id: B2IEN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

395963:BIND RS03680
gene id: 395963:BIND_RS03680
uniprot id: B2IGI6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

395963:BIND RS02695
gene id: 395963:BIND_RS02695
uniprot id: B2IEZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

395963:BIND RS09670
gene id: 395963:BIND_RS09670
uniprot id: B2IED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

395963:BIND RS04140
gene id: 395963:BIND_RS04140
uniprot id: B2IH50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

395963:BIND RS18770
gene id: 395963:BIND_RS18770
uniprot id: B2IL42
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS08595
gene id: 395963:BIND_RS08595
uniprot id: B2ICQ3
names: Similarity
messages: Belongs to the RNase T2 family.

395963:BIND RS00325
gene id: 395963:BIND_RS00325
uniprot id: B2IB24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

395963:BIND RS09565
gene id: 395963:BIND_RS09565
uniprot id: B2IEB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

395963:BIND RS05075
gene id: 395963:BIND_RS05075
uniprot id: B2II61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

395963:BIND RS14495
gene id: 395963:BIND_RS14495
uniprot id: B2IKG3
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS17360
gene id: 395963:BIND_RS17360
uniprot id: B2IEN8
names: Similarity
messages: Belongs to the DprA/Smf family.

395963:BIND RS11715
gene id: 395963:BIND_RS11715
uniprot id: B2IHE5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

395963:BIND RS03460
gene id: 395963:BIND_RS03460
uniprot id: B2IGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

395963:BIND RS17200
gene id: 395963:BIND_RS17200
uniprot id: B2IEK4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

395963:BIND RS09035
gene id: 395963:BIND_RS09035
uniprot id: B2IDH5
names: Similarity
messages: Belongs to the YkuD family.

395963:BIND RS10250
gene id: 395963:BIND_RS10250
uniprot id: B2IF85
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

395963:BIND RS05575
gene id: 395963:BIND_RS05575
uniprot id: B2IIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

395963:BIND RS00165
gene id: 395963:BIND_RS00165
uniprot id: B2IAZ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS05310
gene id: 395963:BIND_RS05310
uniprot id: B2IIJ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

395963:BIND RS14160
gene id: 395963:BIND_RS14160
uniprot id: B2IK02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

395963:BIND RS17620
gene id: 395963:BIND_RS17620
uniprot id: B2IFC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395963:BIND RS19740
gene id: 395963:BIND_RS19740
uniprot id: B2ILM1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS14480
gene id: 395963:BIND_RS14480
uniprot id: B2IKG0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

395963:BIND RS04135
gene id: 395963:BIND_RS04135
uniprot id: B2IH49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS03425
gene id: 395963:BIND_RS03425
uniprot id: B2IGD0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

395963:BIND RS05890
gene id: 395963:BIND_RS05890
uniprot id: B2IJ39
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

395963:BIND RS17610
gene id: 395963:BIND_RS17610
uniprot id: B2IFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395963:BIND RS12155
gene id: 395963:BIND_RS12155
uniprot id: B2IHX3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

395963:BIND RS01370
gene id: 395963:BIND_RS01370
uniprot id: B2ICP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

395963:BIND RS07645
gene id: 395963:BIND_RS07645
uniprot id: B2IB56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

395963:BIND RS16215
gene id: 395963:BIND_RS16215
uniprot id: B2ICZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

395963:BIND RS01995
gene id: 395963:BIND_RS01995
uniprot id: B2IE22
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

395963:BIND RS11215
gene id: 395963:BIND_RS11215
uniprot id: B2IGS4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395963:BIND RS15580
gene id: 395963:BIND_RS15580
uniprot id: B2IBL1
names: Similarity
messages: Belongs to the aldose epimerase family.

395963:BIND RS11175
gene id: 395963:BIND_RS11175
uniprot id: B2IGR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS05195
gene id: 395963:BIND_RS05195
uniprot id: B2II84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

395963:BIND RS12870
gene id: 395963:BIND_RS12870
uniprot id: B2IIT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS00380
gene id: 395963:BIND_RS00380
uniprot id: B2IB35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

395963:BIND RS14005
gene id: 395963:BIND_RS14005
uniprot id: B2IJX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

395963:BIND RS10500
gene id: 395963:BIND_RS10500
uniprot id: B2IFW2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395963:BIND RS03000
gene id: 395963:BIND_RS03000
uniprot id: B2IFN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

395963:BIND RS05000
gene id: 395963:BIND_RS05000
uniprot id: B2II46
names: Cofactor
messages: Binds 2 manganese ions per subunit.

395963:BIND RS01710
gene id: 395963:BIND_RS01710
uniprot id: B2IDD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

395963:BIND RS16595
gene id: 395963:BIND_RS16595
uniprot id: B2ID65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

395963:BIND RS09780
gene id: 395963:BIND_RS09780
uniprot id: B2IEF8
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

395963:BIND RS19745
gene id: 395963:BIND_RS19745
uniprot id: B2ILM2
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS09645
gene id: 395963:BIND_RS09645
uniprot id: B2IED0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

395963:BIND RS11595
gene id: 395963:BIND_RS11595
uniprot id: B2IHC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

395963:BIND RS16355
gene id: 395963:BIND_RS16355
uniprot id: B2ID20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

395963:BIND RS07905
gene id: 395963:BIND_RS07905
uniprot id: B2IBA5
names: Similarity
messages: Belongs to the NodU/CmcH family.

395963:BIND RS06480
gene id: 395963:BIND_RS06480
uniprot id: B2IJP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS14225
gene id: 395963:BIND_RS14225
uniprot id: B2IK11
names: Similarity
messages: Belongs to the IlvD/Edd family.

395963:BIND RS11285
gene id: 395963:BIND_RS11285
uniprot id: B2IGT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS01280
gene id: 395963:BIND_RS01280
uniprot id: B2ICM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

395963:BIND RS06945
gene id: 395963:BIND_RS06945
uniprot id: B2IK76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

395963:BIND RS08630
gene id: 395963:BIND_RS08630
uniprot id: B2ICQ9
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

395963:BIND RS03790
gene id: 395963:BIND_RS03790
uniprot id: B2IGL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

395963:BIND RS05125
gene id: 395963:BIND_RS05125
uniprot id: B2II71
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

395963:BIND RS18450
gene id: 395963:BIND_RS18450
uniprot id: B2IGA7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

395963:BIND RS16400
gene id: 395963:BIND_RS16400
uniprot id: B2ID29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

395963:BIND RS03240
gene id: 395963:BIND_RS03240
uniprot id: B2IFR8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

395963:BIND RS11315
gene id: 395963:BIND_RS11315
uniprot id: B2IGU7
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

395963:BIND RS08740
gene id: 395963:BIND_RS08740
uniprot id: B2ICS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

395963:BIND RS06220
gene id: 395963:BIND_RS06220
uniprot id: B2IJJ2
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

395963:BIND RS17965
gene id: 395963:BIND_RS17965
uniprot id: B2IFJ4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

395963:BIND RS18405
gene id: 395963:BIND_RS18405
uniprot id: B2IG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

395963:BIND RS14470
gene id: 395963:BIND_RS14470
uniprot id: B2IKF8
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

395963:BIND RS02180
gene id: 395963:BIND_RS02180
uniprot id: B2IE59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

395963:BIND RS12520
gene id: 395963:BIND_RS12520
uniprot id: B2IID2
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS18605
gene id: 395963:BIND_RS18605
uniprot id: B2IGW5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

395963:BIND RS06970
gene id: 395963:BIND_RS06970
uniprot id: B2IK81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

395963:BIND RS07935
gene id: 395963:BIND_RS07935
uniprot id: B2IBB1
names: Similarity
messages: Belongs to the RecJ family.

395963:BIND RS12085
gene id: 395963:BIND_RS12085
uniprot id: B2IHW2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

395963:BIND RS16295
gene id: 395963:BIND_RS16295
uniprot id: B2ID10
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

395963:BIND RS04960
gene id: 395963:BIND_RS04960
uniprot id: B2II38
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS11810
gene id: 395963:BIND_RS11810
uniprot id: B2IHG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

395963:BIND RS11370
gene id: 395963:BIND_RS11370
uniprot id: B2IH81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

395963:BIND RS09860
gene id: 395963:BIND_RS09860
uniprot id: B2IEH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

395963:BIND RS00300
gene id: 395963:BIND_RS00300
uniprot id: B2IB19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

395963:BIND RS18625
gene id: 395963:BIND_RS18625
uniprot id: B2IGW9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

395963:BIND RS07535
gene id: 395963:BIND_RS07535
uniprot id: B2IKS8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395963:BIND RS13790
gene id: 395963:BIND_RS13790
uniprot id: B2IJT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

395963:BIND RS08970
gene id: 395963:BIND_RS08970
uniprot id: B2ICX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS16310
gene id: 395963:BIND_RS16310
uniprot id: B2ID11
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

395963:BIND RS02405
gene id: 395963:BIND_RS02405
uniprot id: B2IET2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

395963:BIND RS14785
gene id: 395963:BIND_RS14785
uniprot id: B2IKV9
names: Similarity
messages: Belongs to the peptidase S41A family.

395963:BIND RS18350
gene id: 395963:BIND_RS18350
uniprot id: B2IG89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

395963:BIND RS16945
gene id: 395963:BIND_RS16945
uniprot id: B2IDW5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

395963:BIND RS05405
gene id: 395963:BIND_RS05405
uniprot id: B2IIL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

395963:BIND RS11955
gene id: 395963:BIND_RS11955
uniprot id: B2IHT5
names: Similarity
messages: Belongs to the Gfa family.

395963:BIND RS02100
gene id: 395963:BIND_RS02100
uniprot id: B2IE43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS06515
gene id: 395963:BIND_RS06515
uniprot id: B2IJQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

395963:BIND RS02615
gene id: 395963:BIND_RS02615
uniprot id: B2IEX5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

395963:BIND RS20190
gene id: 395963:BIND_RS20190
uniprot id: B2IIZ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS10130
gene id: 395963:BIND_RS10130
uniprot id: B2IF61
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

395963:BIND RS09610
gene id: 395963:BIND_RS09610
uniprot id: B2IEC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395963:BIND RS02355
gene id: 395963:BIND_RS02355
uniprot id: B2IE96
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS09910
gene id: 395963:BIND_RS09910
uniprot id: B2IEI3
names: Subcellular Location Annotation
messages: Cell inner membrane

395963:BIND RS00675
gene id: 395963:BIND_RS00675
uniprot id: B2IBR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

395963:BIND RS08700
gene id: 395963:BIND_RS08700
uniprot id: B2ICS2
names: Subcellular Location Annotation
messages: Cell outer membrane

395963:BIND RS08055
gene id: 395963:BIND_RS08055
uniprot id: B2IBE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS06940
gene id: 395963:BIND_RS06940
uniprot id: B2IK75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

395963:BIND RS02700
gene id: 395963:BIND_RS02700
uniprot id: B2IEZ1
names: Similarity
messages: Belongs to the UPF0310 family.

395963:BIND RS17750
gene id: 395963:BIND_RS17750
uniprot id: B2IFE9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

395963:BIND RS01930
gene id: 395963:BIND_RS01930
uniprot id: B2IE09
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

395963:BIND RS03820
gene id: 395963:BIND_RS03820
uniprot id: B2IGY4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

395963:BIND RS05870
gene id: 395963:BIND_RS05870
uniprot id: B2IJ35
names: Similarity
messages: Belongs to the HupH/HyaF family.

395963:BIND RS12370
gene id: 395963:BIND_RS12370
uniprot id: B2IIA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

395963:BIND RS12305
gene id: 395963:BIND_RS12305
uniprot id: B2II88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

395963:BIND RS02675
gene id: 395963:BIND_RS02675
uniprot id: B2IEY6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS18595
gene id: 395963:BIND_RS18595
uniprot id: B2IGW3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395963:BIND RS01180
gene id: 395963:BIND_RS01180
uniprot id: B2ICK3
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

395963:BIND RS07170
gene id: 395963:BIND_RS07170
uniprot id: B2IKL2
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS02930
gene id: 395963:BIND_RS02930
uniprot id: B2IFL7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS10445
gene id: 395963:BIND_RS10445
uniprot id: B2IFV1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

395963:BIND RS12090
gene id: 395963:BIND_RS12090
uniprot id: B2IHW3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

395963:BIND RS01340
gene id: 395963:BIND_RS01340
uniprot id: B2ICN3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

395963:BIND RS08560
gene id: 395963:BIND_RS08560
uniprot id: B2ICP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

395963:BIND RS12015
gene id: 395963:BIND_RS12015
uniprot id: B2IHU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

395963:BIND RS09595
gene id: 395963:BIND_RS09595
uniprot id: B2IEC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

395963:BIND RS10685
gene id: 395963:BIND_RS10685
uniprot id: B2IFZ5
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS14190
gene id: 395963:BIND_RS14190
uniprot id: B2IK08
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

395963:BIND RS10815
gene id: 395963:BIND_RS10815
uniprot id: B2IG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

395963:BIND RS18760
gene id: 395963:BIND_RS18760
uniprot id: B2IL40
names: Similarity
messages: Belongs to the RelE toxin family.

395963:BIND RS01000
gene id: 395963:BIND_RS01000
uniprot id: B2ICG7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

395963:BIND RS19700
gene id: 395963:BIND_RS19700
uniprot id: B2ILL4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

395963:BIND RS01570
gene id: 395963:BIND_RS01570
uniprot id: B2IDA6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS18485
gene id: 395963:BIND_RS18485
uniprot id: B2IGB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

395963:BIND RS12330
gene id: 395963:BIND_RS12330
uniprot id: B2II93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

395963:BIND RS10285
gene id: 395963:BIND_RS10285
uniprot id: B2IF93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

395963:BIND RS07320
gene id: 395963:BIND_RS07320
uniprot id: B2IKP2
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

395963:BIND RS20135
gene id: 395963:BIND_RS20135
uniprot id: B2IDN3
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

395963:BIND RS18200
gene id: 395963:BIND_RS18200
uniprot id: B2IG62
names: Similarity
messages: Belongs to the phosphohexose mutase family.

395963:BIND RS02600
gene id: 395963:BIND_RS02600
uniprot id: B2IEX2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

395963:BIND RS17265
gene id: 395963:BIND_RS17265
uniprot id: B2IEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

395963:BIND RS17710
gene id: 395963:BIND_RS17710
uniprot id: B2IFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

395963:BIND RS07865
gene id: 395963:BIND_RS07865
uniprot id: B2IB98
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

395963:BIND RS08995
gene id: 395963:BIND_RS08995
uniprot id: B2ICX0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS11860
gene id: 395963:BIND_RS11860
uniprot id: B2IHR6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

395963:BIND RS05995
gene id: 395963:BIND_RS05995
uniprot id: B2IJ60
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

395963:BIND RS01210
gene id: 395963:BIND_RS01210
uniprot id: B2ICK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

395963:BIND RS07950
gene id: 395963:BIND_RS07950
uniprot id: B2IBB5
names: Similarity
messages: Belongs to the GppA/Ppx family.

395963:BIND RS01045
gene id: 395963:BIND_RS01045
uniprot id: B2ICH5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

395963:BIND RS19255
gene id: 395963:BIND_RS19255
uniprot id: B2ILD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS08565
gene id: 395963:BIND_RS08565
uniprot id: B2ICP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

395963:BIND RS12840
gene id: 395963:BIND_RS12840
uniprot id: B2IIT2
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS00670
gene id: 395963:BIND_RS00670
uniprot id: B2IBR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

395963:BIND RS06975
gene id: 395963:BIND_RS06975
uniprot id: B2IK82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

395963:BIND RS06870
gene id: 395963:BIND_RS06870
uniprot id: B2IK61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

395963:BIND RS17740
gene id: 395963:BIND_RS17740
uniprot id: B2IFE8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

395963:BIND RS06910
gene id: 395963:BIND_RS06910
uniprot id: B2IK69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

395963:BIND RS05990
gene id: 395963:BIND_RS05990
uniprot id: B2IJ59
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS10460
gene id: 395963:BIND_RS10460
uniprot id: B2IFV4
names: Similarity
messages: Belongs to the SDHAF4 family.

395963:BIND RS03955
gene id: 395963:BIND_RS03955
uniprot id: B2IH12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

395963:BIND RS06725
gene id: 395963:BIND_RS06725
uniprot id: B2IK33
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

395963:BIND RS11675
gene id: 395963:BIND_RS11675
uniprot id: B2IHD7
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

395963:BIND RS18805
gene id: 395963:BIND_RS18805
uniprot id: B2IL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

395963:BIND RS01755
gene id: 395963:BIND_RS01755
uniprot id: B2IDE8
names: Similarity
messages: Belongs to the GST superfamily.

395963:BIND RS09160
gene id: 395963:BIND_RS09160
uniprot id: B2IDK1
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

395963:BIND RS01690
gene id: 395963:BIND_RS01690
uniprot id: B2IDD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

395963:BIND RS00125
gene id: 395963:BIND_RS00125
uniprot id: B2IAY3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

395963:BIND RS05825
gene id: 395963:BIND_RS05825
uniprot id: B2IJ26
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

395963:BIND RS14070
gene id: 395963:BIND_RS14070
uniprot id: B2IJY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

395963:BIND RS09635
gene id: 395963:BIND_RS09635
uniprot id: B2IEC9
names: Subcellular Location Annotation
messages: Cell inner membrane

395963:BIND RS05485
gene id: 395963:BIND_RS05485
uniprot id: B2IIN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

395963:BIND RS08450
gene id: 395963:BIND_RS08450
uniprot id: B2IC43
names: Similarity
messages: Belongs to the ClpA/ClpB family.

395963:BIND RS19245
gene id: 395963:BIND_RS19245
uniprot id: B2ILD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

395963:BIND RS10850
gene id: 395963:BIND_RS10850
uniprot id: B2IG27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

395963:BIND RS12515
gene id: 395963:BIND_RS12515
uniprot id: B2IID1
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS17220
gene id: 395963:BIND_RS17220
uniprot id: B2IEK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

395963:BIND RS19260
gene id: 395963:BIND_RS19260
uniprot id: B2ILD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS02315
gene id: 395963:BIND_RS02315
uniprot id: B2IE84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

395963:BIND RS18085
gene id: 395963:BIND_RS18085
uniprot id: B2IG40
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

395963:BIND RS14110
gene id: 395963:BIND_RS14110
uniprot id: B2IJZ2
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

395963:BIND RS17015
gene id: 395963:BIND_RS17015
uniprot id: B2IDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

395963:BIND RS06830
gene id: 395963:BIND_RS06830
uniprot id: B2IK53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

395963:BIND RS02115
gene id: 395963:BIND_RS02115
uniprot id: B2IE46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

395963:BIND RS16475
gene id: 395963:BIND_RS16475
uniprot id: B2ID42
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

395963:BIND RS08335
gene id: 395963:BIND_RS08335
uniprot id: B2IC20
names: Similarity
messages: Belongs to the peptidase S9A family.

395963:BIND RS12505
gene id: 395963:BIND_RS12505
uniprot id: B2IIC9
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS09465
gene id: 395963:BIND_RS09465
uniprot id: B2IDQ6
names: Similarity
messages: Belongs to the virb1 family.

395963:BIND RS10360
gene id: 395963:BIND_RS10360
uniprot id: B2IFA9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

395963:BIND RS02035
gene id: 395963:BIND_RS02035
uniprot id: B2IE30
names: Similarity
messages: Belongs to the NifZ family.

395963:BIND RS10550
gene id: 395963:BIND_RS10550
uniprot id: B2IFX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS07890
gene id: 395963:BIND_RS07890
uniprot id: B2IBA2
names: Similarity
messages: Belongs to the TPP enzyme family.

395963:BIND RS10355
gene id: 395963:BIND_RS10355
uniprot id: B2IFA8
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

395963:BIND RS12280
gene id: 395963:BIND_RS12280
uniprot id: B2IHZ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS13675
gene id: 395963:BIND_RS13675
uniprot id: B2IJH1
names: Similarity
messages: Belongs to the HesB/IscA family.

395963:BIND RS09665
gene id: 395963:BIND_RS09665
uniprot id: B2IED4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

395963:BIND RS06025
gene id: 395963:BIND_RS06025
uniprot id: B2IJ66
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

395963:BIND RS09045
gene id: 395963:BIND_RS09045
uniprot id: B2IDH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

395963:BIND RS10310
gene id: 395963:BIND_RS10310
uniprot id: B2IF99
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

395963:BIND RS16930
gene id: 395963:BIND_RS16930
uniprot id: B2IDW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

395963:BIND RS07085
gene id: 395963:BIND_RS07085
uniprot id: B2IKA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS05265
gene id: 395963:BIND_RS05265
uniprot id: B2III8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

395963:BIND RS04690
gene id: 395963:BIND_RS04690
uniprot id: B2IHP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

395963:BIND RS00025
gene id: 395963:BIND_RS00025
uniprot id: B2IAW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

395963:BIND RS15320
gene id: 395963:BIND_RS15320
uniprot id: B2IBG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

395963:BIND RS12055
gene id: 395963:BIND_RS12055
uniprot id: B2IHV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395963:BIND RS04305
gene id: 395963:BIND_RS04305
uniprot id: B2IHH5
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

395963:BIND RS17770
gene id: 395963:BIND_RS17770
uniprot id: B2IFF3
names: Similarity
messages: Belongs to the UPF0102 family.

395963:BIND RS18000
gene id: 395963:BIND_RS18000
uniprot id: B2IFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

395963:BIND RS15795
gene id: 395963:BIND_RS15795
uniprot id: B2IC84
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

395963:BIND RS13625
gene id: 395963:BIND_RS13625
uniprot id: B2IJG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

395963:BIND RS17150
gene id: 395963:BIND_RS17150
uniprot id: B2IEJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

395963:BIND RS08750
gene id: 395963:BIND_RS08750
uniprot id: B2ICT1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

395963:BIND RS01525
gene id: 395963:BIND_RS01525
uniprot id: B2ID97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

395963:BIND RS01350
gene id: 395963:BIND_RS01350
uniprot id: B2ICN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

395963:BIND RS18280
gene id: 395963:BIND_RS18280
uniprot id: B2IG77
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS15410
gene id: 395963:BIND_RS15410
uniprot id: B2IBH9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

395963:BIND RS01635
gene id: 395963:BIND_RS01635
uniprot id: B2IDB8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

395963:BIND RS01970
gene id: 395963:BIND_RS01970
uniprot id: B2IE17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395963:BIND RS04940
gene id: 395963:BIND_RS04940
uniprot id: B2II34
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

395963:BIND RS10290
gene id: 395963:BIND_RS10290
uniprot id: B2IF94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

395963:BIND RS16180
gene id: 395963:BIND_RS16180
uniprot id: B2ICY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

395963:BIND RS03840
gene id: 395963:BIND_RS03840
uniprot id: B2IGY8
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

395963:BIND RS10535
gene id: 395963:BIND_RS10535
uniprot id: B2IFW8
names: Similarity
messages: Belongs to the hyi family.

395963:BIND RS17535
gene id: 395963:BIND_RS17535
uniprot id: B2IES3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS11280
gene id: 395963:BIND_RS11280
uniprot id: B2IGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

395963:BIND RS10220
gene id: 395963:BIND_RS10220
uniprot id: B2IF79
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

395963:BIND RS12345
gene id: 395963:BIND_RS12345
uniprot id: B2II96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

395963:BIND RS04485
gene id: 395963:BIND_RS04485
uniprot id: B2IHL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

395963:BIND RS00405
gene id: 395963:BIND_RS00405
uniprot id: B2IB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

395963:BIND RS02200
gene id: 395963:BIND_RS02200
uniprot id: B2IE62
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

395963:BIND RS01515
gene id: 395963:BIND_RS01515
uniprot id: B2ID95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

395963:BIND RS01415
gene id: 395963:BIND_RS01415
uniprot id: B2ID77
names: Subcellular Location Annotation
messages: Cell inner membrane

395963:BIND RS03785
gene id: 395963:BIND_RS03785
uniprot id: B2IGK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria (By similarity).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains (By similarity).

395963:BIND RS15875
gene id: 395963:BIND_RS15875
uniprot id: B2ICA0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

395963:BIND RS07065
gene id: 395963:BIND_RS07065
uniprot id: B2IKA0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS15690
gene id: 395963:BIND_RS15690
uniprot id: B2IC62
names: Subcellular Location Annotation
messages: Cytoplasm

395963:BIND RS03465
gene id: 395963:BIND_RS03465
uniprot id: B2IGD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS15550
gene id: 395963:BIND_RS15550
uniprot id: B2IBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

395963:BIND RS12820
gene id: 395963:BIND_RS12820
uniprot id: B2IIS8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

395963:BIND RS05480
gene id: 395963:BIND_RS05480
uniprot id: B2IIN0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

395963:BIND RS02205
gene id: 395963:BIND_RS02205
uniprot id: B2IE63
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

395963:BIND RS03625
gene id: 395963:BIND_RS03625
uniprot id: B2IGH4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

395963:BIND RS01290
gene id: 395963:BIND_RS01290
uniprot id: B2ICM5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

395963:BIND RS18155
gene id: 395963:BIND_RS18155
uniprot id: B2IG54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

395963:BIND RS18380
gene id: 395963:BIND_RS18380
uniprot id: B2IG94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

395963:BIND RS16205
gene id: 395963:BIND_RS16205
uniprot id: B2ICZ3
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

395963:BIND RS03795
gene id: 395963:BIND_RS03795
uniprot id: B2IGL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

395963:BIND RS02855
gene id: 395963:BIND_RS02855
uniprot id: B2IF22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

395963:BIND RS00190
gene id: 395963:BIND_RS00190
uniprot id: B2IAZ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS08980
gene id: 395963:BIND_RS08980
uniprot id: B2ICY0
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

395963:BIND RS01560
gene id: 395963:BIND_RS01560
uniprot id: B2IDA4
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

395963:BIND RS04325
gene id: 395963:BIND_RS04325
uniprot id: B2IHH9
names: Similarity
messages: Belongs to the peptidase M1 family.

395963:BIND RS14440
gene id: 395963:BIND_RS14440
uniprot id: B2IKF2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS07675
gene id: 395963:BIND_RS07675
uniprot id: B2IB62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS14770
gene id: 395963:BIND_RS14770
uniprot id: B2IKV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

395963:BIND RS12390
gene id: 395963:BIND_RS12390
uniprot id: B2IIA5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS17380
gene id: 395963:BIND_RS17380
uniprot id: B2IEP2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

395963:BIND RS18190
gene id: 395963:BIND_RS18190
uniprot id: B2IG60
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

395963:BIND RS10265
gene id: 395963:BIND_RS10265
uniprot id: B2IF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

395963:BIND RS06820
gene id: 395963:BIND_RS06820
uniprot id: B2IK51
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

395963:BIND RS19455
gene id: 395963:BIND_RS19455
uniprot id: B2ILG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395963:BIND RS00030
gene id: 395963:BIND_RS00030
uniprot id: B2IAW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

395963:BIND RS04530
gene id: 395963:BIND_RS04530
uniprot id: B2IHL9
names: Similarity
messages: Belongs to the aspartokinase family.

395963:BIND RS00040
gene id: 395963:BIND_RS00040
uniprot id: B2IAW6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

395963:BIND RS14510
gene id: 395963:BIND_RS14510
uniprot id: B2IKG6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS10425
gene id: 395963:BIND_RS10425
uniprot id: B2IFU7
names: Similarity
messages: Belongs to the DinB family.

395963:BIND RS06290
gene id: 395963:BIND_RS06290
uniprot id: B2IJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

395963:BIND RS14290
gene id: 395963:BIND_RS14290
uniprot id: B2IKC2
names: Similarity
messages: Belongs to the TPP enzyme family.

395963:BIND RS00595
gene id: 395963:BIND_RS00595
uniprot id: B2IBQ3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

395963:BIND RS17400
gene id: 395963:BIND_RS17400
uniprot id: B2IEP6
names: Similarity
messages: Belongs to the BolA/IbaG family.

395963:BIND RS17665
gene id: 395963:BIND_RS17665
uniprot id: B2IFD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

395963:BIND RS03845
gene id: 395963:BIND_RS03845
uniprot id: B2IGY9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS05750
gene id: 395963:BIND_RS05750
uniprot id: B2IJ12
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

395963:BIND RS03705
gene id: 395963:BIND_RS03705
uniprot id: B2IGJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

395963:BIND RS14815
gene id: 395963:BIND_RS14815
uniprot id: B2IKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

395963:BIND RS10880
gene id: 395963:BIND_RS10880
uniprot id: B2IG14
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

395963:BIND RS02495
gene id: 395963:BIND_RS02495
uniprot id: B2IEV2
names: Function
names: Similarity
messages: Could be a 3Fe-4S cluster-containing protein.
messages: To ferredoxins from P.putida and C.tartarivorum, ferredoxin I from A.vinelandii, ferredoxin II from D.desulfuricans.

395963:BIND RS14705
gene id: 395963:BIND_RS14705
uniprot id: B2IKK3
names: Similarity
messages: Belongs to the bacterial glucokinase family.

395963:BIND RS07730
gene id: 395963:BIND_RS07730
uniprot id: B2IB73
names: Function
messages: Acts on leucine, isoleucine and valine.

395963:BIND RS17525
gene id: 395963:BIND_RS17525
uniprot id: B2IES1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

395963:BIND RS01255
gene id: 395963:BIND_RS01255
uniprot id: B2ICL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

395963:BIND RS02095
gene id: 395963:BIND_RS02095
uniprot id: B2IE42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

395963:BIND RS00630
gene id: 395963:BIND_RS00630
uniprot id: B2IBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

395963:BIND RS18490
gene id: 395963:BIND_RS18490
uniprot id: B2IGB5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

395963:BIND RS06435
gene id: 395963:BIND_RS06435
uniprot id: B2IJN8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

395963:BIND RS15660
gene id: 395963:BIND_RS15660
uniprot id: B2IBM6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS09505
gene id: 395963:BIND_RS09505
uniprot id: B2IEA4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

395963:BIND RS06960
gene id: 395963:BIND_RS06960
uniprot id: B2IK79
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

395963:BIND RS01530
gene id: 395963:BIND_RS01530
uniprot id: B2ID98
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS19310
gene id: 395963:BIND_RS19310
uniprot id: B2ILE8
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

395963:BIND RS10705
gene id: 395963:BIND_RS10705
uniprot id: B2IFZ9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

395963:BIND RS13745
gene id: 395963:BIND_RS13745
uniprot id: B2IJD5
names: Similarity
messages: Belongs to the peptidase C40 family.

395963:BIND RS10230
gene id: 395963:BIND_RS10230
uniprot id: B2IF81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

395963:BIND RS09090
gene id: 395963:BIND_RS09090
uniprot id: B2IDI6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

395963:BIND RS08215
gene id: 395963:BIND_RS08215
uniprot id: B2IBZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

395963:BIND RS02830
gene id: 395963:BIND_RS02830
uniprot id: B2IF17
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS01975
gene id: 395963:BIND_RS01975
uniprot id: B2IE18
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

395963:BIND RS12860
gene id: 395963:BIND_RS12860
uniprot id: B2IIT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

395963:BIND RS13560
gene id: 395963:BIND_RS13560
uniprot id: B2IJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

395963:BIND RS05665
gene id: 395963:BIND_RS05665
uniprot id: B2IIR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

395963:BIND RS05950
gene id: 395963:BIND_RS05950
uniprot id: B2IJ51
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

395963:BIND RS11795
gene id: 395963:BIND_RS11795
uniprot id: B2IHG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

395963:BIND RS00010
gene id: 395963:BIND_RS00010
uniprot id: B2IAW0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

395963:BIND RS05785
gene id: 395963:BIND_RS05785
uniprot id: B2IJ18
names: Function
messages: Acts on leucine, isoleucine and valine.

395963:BIND RS10225
gene id: 395963:BIND_RS10225
uniprot id: B2IF80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

395963:BIND RS01810
gene id: 395963:BIND_RS01810
uniprot id: B2IDF9
names: Similarity
messages: Belongs to the peptidase S11 family.

395963:BIND RS00205
gene id: 395963:BIND_RS00205
uniprot id: B2IAZ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS04915
gene id: 395963:BIND_RS04915
uniprot id: B2II29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS17085
gene id: 395963:BIND_RS17085
uniprot id: B2IDZ4
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

395963:BIND RS18185
gene id: 395963:BIND_RS18185
uniprot id: B2IG59
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

395963:BIND RS17450
gene id: 395963:BIND_RS17450
uniprot id: B2IEQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

395963:BIND RS13975
gene id: 395963:BIND_RS13975
uniprot id: B2IJW7
names: Similarity
messages: Belongs to the creatininase superfamily.

395963:BIND RS16260
gene id: 395963:BIND_RS16260
uniprot id: B2ID03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

395963:BIND RS12095
gene id: 395963:BIND_RS12095
uniprot id: B2IHW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395963:BIND RS14230
gene id: 395963:BIND_RS14230
uniprot id: B2IK12
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS02430
gene id: 395963:BIND_RS02430
uniprot id: B2IET7
names: Similarity
messages: Belongs to the NifX/NifY family.

395963:BIND RS06925
gene id: 395963:BIND_RS06925
uniprot id: B2IK72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

395963:BIND RS01215
gene id: 395963:BIND_RS01215
uniprot id: B2ICL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

395963:BIND RS03720
gene id: 395963:BIND_RS03720
uniprot id: B2IGJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

395963:BIND RS10940
gene id: 395963:BIND_RS10940
uniprot id: B2IGM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

395963:BIND RS07330
gene id: 395963:BIND_RS07330
uniprot id: B2IKP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

395963:BIND RS00515
gene id: 395963:BIND_RS00515
uniprot id: B2IBN8
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

395963:BIND RS00540
gene id: 395963:BIND_RS00540
uniprot id: B2IBP3
names: Similarity
messages: Belongs to the DEAD box helicase family.

395963:BIND RS02780
gene id: 395963:BIND_RS02780
uniprot id: B2IF07
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS18160
gene id: 395963:BIND_RS18160
uniprot id: B2IG55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

395963:BIND RS06020
gene id: 395963:BIND_RS06020
uniprot id: B2IJ65
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS01765
gene id: 395963:BIND_RS01765
uniprot id: B2IDF0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

395963:BIND RS00465
gene id: 395963:BIND_RS00465
uniprot id: B2IBM9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

395963:BIND RS11805
gene id: 395963:BIND_RS11805
uniprot id: B2IHG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS05535
gene id: 395963:BIND_RS05535
uniprot id: B2IIN9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS02350
gene id: 395963:BIND_RS02350
uniprot id: B2IE95
names: Similarity
messages: Belongs to the GST superfamily.

395963:BIND RS17305
gene id: 395963:BIND_RS17305
uniprot id: B2IEM7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395963:BIND RS07735
gene id: 395963:BIND_RS07735
uniprot id: B2IB74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

395963:BIND RS07430
gene id: 395963:BIND_RS07430
uniprot id: B2IKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

395963:BIND RS08820
gene id: 395963:BIND_RS08820
uniprot id: B2ICU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

395963:BIND RS01835
gene id: 395963:BIND_RS01835
uniprot id: B2IDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

395963:BIND RS13640
gene id: 395963:BIND_RS13640
uniprot id: B2IJG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

395963:BIND RS13385
gene id: 395963:BIND_RS13385
uniprot id: B2IJB3
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS00395
gene id: 395963:BIND_RS00395
uniprot id: B2IB38
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

395963:BIND RS12225
gene id: 395963:BIND_RS12225
uniprot id: B2IHY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

395963:BIND RS08260
gene id: 395963:BIND_RS08260
uniprot id: B2IC06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395963:BIND RS11295
gene id: 395963:BIND_RS11295
uniprot id: B2IGU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

395963:BIND RS03025
gene id: 395963:BIND_RS03025
uniprot id: B2IFN4
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS10755
gene id: 395963:BIND_RS10755
uniprot id: B2IG08
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS04460
gene id: 395963:BIND_RS04460
uniprot id: B2IHK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS09365
gene id: 395963:BIND_RS09365
uniprot id: B2IDN9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

395963:BIND RS02490
gene id: 395963:BIND_RS02490
uniprot id: B2IEV1
names: Function
names: Similarity
messages: Belongs to the ETF-QO/FixC family.
messages: Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and reduces a quinone.
messages: Part of an electron transfer system.

395963:BIND RS00500
gene id: 395963:BIND_RS00500
uniprot id: B2IBN5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

395963:BIND RS09240
gene id: 395963:BIND_RS09240
uniprot id: B2IDL6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS18715
gene id: 395963:BIND_RS18715
uniprot id: B2IL31
names: Similarity
messages: Belongs to the GSP E family.

395963:BIND RS15380
gene id: 395963:BIND_RS15380
uniprot id: B2IBH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

395963:BIND RS09050
gene id: 395963:BIND_RS09050
uniprot id: B2IDH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

395963:BIND RS07775
gene id: 395963:BIND_RS07775
uniprot id: B2IB82
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

395963:BIND RS17255
gene id: 395963:BIND_RS17255
uniprot id: B2IEL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

395963:BIND RS12420
gene id: 395963:BIND_RS12420
uniprot id: B2IIB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS02935
gene id: 395963:BIND_RS02935
uniprot id: B2IFL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS02825
gene id: 395963:BIND_RS02825
uniprot id: B2IF16
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

395963:BIND RS15600
gene id: 395963:BIND_RS15600
uniprot id: B2IBL5
names: Similarity
messages: Belongs to the DapA family.

395963:BIND RS02460
gene id: 395963:BIND_RS02460
uniprot id: B2IEU2
names: Similarity
messages: Belongs to the HesB/IscA family.

395963:BIND RS00865
gene id: 395963:BIND_RS00865
uniprot id: B2IBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

395963:BIND RS01460
gene id: 395963:BIND_RS01460
uniprot id: B2ID85
names: Similarity
messages: Belongs to the manganese catalase family.

395963:BIND RS01100
gene id: 395963:BIND_RS01100
uniprot id: B2ICI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

395963:BIND RS14265
gene id: 395963:BIND_RS14265
uniprot id: B2IKB7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

395963:BIND RS16610
gene id: 395963:BIND_RS16610
uniprot id: B2ID68
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

395963:BIND RS18100
gene id: 395963:BIND_RS18100
uniprot id: B2IG43
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

395963:BIND RS12385
gene id: 395963:BIND_RS12385
uniprot id: B2IIA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS10050
gene id: 395963:BIND_RS10050
uniprot id: B2IF44
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

395963:BIND RS07280
gene id: 395963:BIND_RS07280
uniprot id: B2IKN4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

395963:BIND RS14720
gene id: 395963:BIND_RS14720
uniprot id: B2IKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

395963:BIND RS13920
gene id: 395963:BIND_RS13920
uniprot id: B2IJV6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

395963:BIND RS08190
gene id: 395963:BIND_RS08190
uniprot id: B2IBZ3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS18585
gene id: 395963:BIND_RS18585
uniprot id: B2IGW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

395963:BIND RS10865
gene id: 395963:BIND_RS10865
uniprot id: B2IG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

395963:BIND RS16690
gene id: 395963:BIND_RS16690
uniprot id: B2IDR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS04415
gene id: 395963:BIND_RS04415
uniprot id: B2IHJ7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

395963:BIND RS07000
gene id: 395963:BIND_RS07000
uniprot id: B2IK87
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

395963:BIND RS10060
gene id: 395963:BIND_RS10060
uniprot id: B2IF46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

395963:BIND RS15720
gene id: 395963:BIND_RS15720
uniprot id: B2IC68
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

395963:BIND RS02475
gene id: 395963:BIND_RS02475
uniprot id: B2IEU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifW family.
messages: Homotrimer; associates with NifD.
messages: May protect the nitrogenase Fe-Mo protein from oxidative damage.

395963:BIND RS02765
gene id: 395963:BIND_RS02765
uniprot id: B2IF04
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

395963:BIND RS09355
gene id: 395963:BIND_RS09355
uniprot id: B2IDN7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

395963:BIND RS10920
gene id: 395963:BIND_RS10920
uniprot id: B2IGL8
names: Similarity
messages: Belongs to the peptidase M24B family.

395963:BIND RS04830
gene id: 395963:BIND_RS04830
uniprot id: B2II14
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

395963:BIND RS12510
gene id: 395963:BIND_RS12510
uniprot id: B2IID0
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS08625
gene id: 395963:BIND_RS08625
uniprot id: B2ICQ8
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

395963:BIND RS18650
gene id: 395963:BIND_RS18650
uniprot id: B2IGX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395963:BIND RS12940
gene id: 395963:BIND_RS12940
uniprot id: B2IIV2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS15640
gene id: 395963:BIND_RS15640
uniprot id: B2IBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

395963:BIND RS17160
gene id: 395963:BIND_RS17160
uniprot id: B2IEJ7
names: Similarity
messages: Belongs to the UPF0174 family.

395963:BIND RS09370
gene id: 395963:BIND_RS09370
uniprot id: B2IDP0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

395963:BIND RS09055
gene id: 395963:BIND_RS09055
uniprot id: B2IDH9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

395963:BIND RS16615
gene id: 395963:BIND_RS16615
uniprot id: B2ID69
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

395963:BIND RS00085
gene id: 395963:BIND_RS00085
uniprot id: B2IAX5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

395963:BIND RS01170
gene id: 395963:BIND_RS01170
uniprot id: B2ICK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

395963:BIND RS04195
gene id: 395963:BIND_RS04195
uniprot id: B2IH62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

395963:BIND RS00250
gene id: 395963:BIND_RS00250
uniprot id: B2IB09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

395963:BIND RS05025
gene id: 395963:BIND_RS05025
uniprot id: B2II51
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

395963:BIND RS16385
gene id: 395963:BIND_RS16385
uniprot id: B2ID26
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

395963:BIND RS16290
gene id: 395963:BIND_RS16290
uniprot id: B2ID09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

395963:BIND RS18345
gene id: 395963:BIND_RS18345
uniprot id: B2IG88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

395963:BIND RS07795
gene id: 395963:BIND_RS07795
uniprot id: B2IB86
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

395963:BIND RS17245
gene id: 395963:BIND_RS17245
uniprot id: B2IEL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

395963:BIND RS07635
gene id: 395963:BIND_RS07635
uniprot id: B2IB54
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

395963:BIND RS10505
gene id: 395963:BIND_RS10505
uniprot id: B2IFW3
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS14010
gene id: 395963:BIND_RS14010
uniprot id: B2IJX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395963:BIND RS15565
gene id: 395963:BIND_RS15565
uniprot id: B2IBK8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS16860
gene id: 395963:BIND_RS16860
uniprot id: B2IDU9
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

395963:BIND RS08110
gene id: 395963:BIND_RS08110
uniprot id: B2IBX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

395963:BIND RS07290
gene id: 395963:BIND_RS07290
uniprot id: B2IKN6
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

395963:BIND RS01480
gene id: 395963:BIND_RS01480
uniprot id: B2ID88
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

395963:BIND RS01270
gene id: 395963:BIND_RS01270
uniprot id: B2ICM1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

395963:BIND RS08680
gene id: 395963:BIND_RS08680
uniprot id: B2ICR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

395963:BIND RS14740
gene id: 395963:BIND_RS14740
uniprot id: B2IKV0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS04750
gene id: 395963:BIND_RS04750
uniprot id: B2II00
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

395963:BIND RS00350
gene id: 395963:BIND_RS00350
uniprot id: B2IB29
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

395963:BIND RS07050
gene id: 395963:BIND_RS07050
uniprot id: B2IK97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

395963:BIND RS03920
gene id: 395963:BIND_RS03920
uniprot id: B2IH05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

395963:BIND RS07545
gene id: 395963:BIND_RS07545
uniprot id: B2IKT0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395963:BIND RS07995
gene id: 395963:BIND_RS07995
uniprot id: B2IBC4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homomer.

395963:BIND RS17865
gene id: 395963:BIND_RS17865
uniprot id: B2IFH2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

395963:BIND RS05040
gene id: 395963:BIND_RS05040
uniprot id: B2II54
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

395963:BIND RS05070
gene id: 395963:BIND_RS05070
uniprot id: B2II60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

395963:BIND RS04050
gene id: 395963:BIND_RS04050
uniprot id: B2IH32
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395963:BIND RS13300
gene id: 395963:BIND_RS13300
uniprot id: B2IJ99
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS05860
gene id: 395963:BIND_RS05860
uniprot id: B2IJ33
names: Similarity
messages: Belongs to the HupF/HypC family.

395963:BIND RS15975
gene id: 395963:BIND_RS15975
uniprot id: B2ICC0
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

395963:BIND RS19040
gene id: 395963:BIND_RS19040
uniprot id: B2ILA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

395963:BIND RS16715
gene id: 395963:BIND_RS16715
uniprot id: B2IDS2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

395963:BIND RS15035
gene id: 395963:BIND_RS15035
uniprot id: B2IL05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS05335
gene id: 395963:BIND_RS05335
uniprot id: B2IIK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

395963:BIND RS00330
gene id: 395963:BIND_RS00330
uniprot id: B2IB25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

395963:BIND RS00810
gene id: 395963:BIND_RS00810
uniprot id: B2IBU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS17340
gene id: 395963:BIND_RS17340
uniprot id: B2IEN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

395963:BIND RS01175
gene id: 395963:BIND_RS01175
uniprot id: B2ICK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

395963:BIND RS19300
gene id: 395963:BIND_RS19300
uniprot id: B2ILE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

395963:BIND RS04775
gene id: 395963:BIND_RS04775
uniprot id: B2II04
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS03645
gene id: 395963:BIND_RS03645
uniprot id: B2IGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

395963:BIND RS17675
gene id: 395963:BIND_RS17675
uniprot id: B2IFD5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

395963:BIND RS13880
gene id: 395963:BIND_RS13880
uniprot id: B2IJU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

395963:BIND RS03760
gene id: 395963:BIND_RS03760
uniprot id: B2IGK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

395963:BIND RS10000
gene id: 395963:BIND_RS10000
uniprot id: B2IF34
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

395963:BIND RS12930
gene id: 395963:BIND_RS12930
uniprot id: B2IIV0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

395963:BIND RS12185
gene id: 395963:BIND_RS12185
uniprot id: B2IHX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS17250
gene id: 395963:BIND_RS17250
uniprot id: B2IEL6
names: Similarity
messages: Belongs to the ArsC family.

395963:BIND RS07660
gene id: 395963:BIND_RS07660
uniprot id: B2IB59
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

395963:BIND RS02690
gene id: 395963:BIND_RS02690
uniprot id: B2IEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

395963:BIND RS07705
gene id: 395963:BIND_RS07705
uniprot id: B2IB68
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

395963:BIND RS14385
gene id: 395963:BIND_RS14385
uniprot id: B2IKE1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

395963:BIND RS15505
gene id: 395963:BIND_RS15505
uniprot id: B2IBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

395963:BIND RS15260
gene id: 395963:BIND_RS15260
uniprot id: B2IBF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

395963:BIND RS17735
gene id: 395963:BIND_RS17735
uniprot id: B2IFE7
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS04795
gene id: 395963:BIND_RS04795
uniprot id: B2II07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

395963:BIND RS11000
gene id: 395963:BIND_RS11000
uniprot id: B2IGN5
names: Similarity
messages: Belongs to the thioredoxin family.

395963:BIND RS08510
gene id: 395963:BIND_RS08510
uniprot id: B2IC55
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

395963:BIND RS03810
gene id: 395963:BIND_RS03810
uniprot id: B2IGE7
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

395963:BIND RS17530
gene id: 395963:BIND_RS17530
uniprot id: B2IES2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

395963:BIND RS12075
gene id: 395963:BIND_RS12075
uniprot id: B2IHW0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395963:BIND RS07980
gene id: 395963:BIND_RS07980
uniprot id: B2IBC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

395963:BIND RS11980
gene id: 395963:BIND_RS11980
uniprot id: B2IHU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BA14k family.
messages: Cell membrane
messages: Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.
messages: Membrane

395963:BIND RS18020
gene id: 395963:BIND_RS18020
uniprot id: B2IFK6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

395963:BIND RS15335
gene id: 395963:BIND_RS15335
uniprot id: B2IBG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

395963:BIND RS02310
gene id: 395963:BIND_RS02310
uniprot id: B2IE83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

395963:BIND RS01750
gene id: 395963:BIND_RS01750
uniprot id: B2IDE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

395963:BIND RS12455
gene id: 395963:BIND_RS12455
uniprot id: B2IIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

395963:BIND RS09870
gene id: 395963:BIND_RS09870
uniprot id: B2IEH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

395963:BIND RS02945
gene id: 395963:BIND_RS02945
uniprot id: B2IFM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS06920
gene id: 395963:BIND_RS06920
uniprot id: B2IK71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

395963:BIND RS13590
gene id: 395963:BIND_RS13590
uniprot id: B2IJF4
names: Function
names: Similarity
messages: Belongs to the ADC family.
messages: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.

395963:BIND RS09520
gene id: 395963:BIND_RS09520
uniprot id: B2IEA7
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS06950
gene id: 395963:BIND_RS06950
uniprot id: B2IK77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

395963:BIND RS03595
gene id: 395963:BIND_RS03595
uniprot id: B2IGG8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

395963:BIND RS17005
gene id: 395963:BIND_RS17005
uniprot id: B2IDX7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

395963:BIND RS05905
gene id: 395963:BIND_RS05905
uniprot id: B2IJ42
names: Similarity
messages: Belongs to the HypD family.

395963:BIND RS07365
gene id: 395963:BIND_RS07365
uniprot id: B2IKQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395963:BIND RS13340
gene id: 395963:BIND_RS13340
uniprot id: B2IJ71
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

395963:BIND RS06120
gene id: 395963:BIND_RS06120
uniprot id: B2IJ84
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS01300
gene id: 395963:BIND_RS01300
uniprot id: B2ICM7
names: Similarity
messages: Belongs to the DEAD box helicase family.

395963:BIND RS16190
gene id: 395963:BIND_RS16190
uniprot id: B2ICZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

395963:BIND RS12415
gene id: 395963:BIND_RS12415
uniprot id: B2IIB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

395963:BIND RS05830
gene id: 395963:BIND_RS05830
uniprot id: B2IJ27
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

395963:BIND RS05565
gene id: 395963:BIND_RS05565
uniprot id: B2IIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

395963:BIND RS09450
gene id: 395963:BIND_RS09450
uniprot id: B2IDQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

395963:BIND RS11835
gene id: 395963:BIND_RS11835
uniprot id: B2IHR1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

395963:BIND RS00805
gene id: 395963:BIND_RS00805
uniprot id: B2IBU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

395963:BIND RS19140
gene id: 395963:BIND_RS19140
uniprot id: B2ILC0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395963:BIND RS06655
gene id: 395963:BIND_RS06655
uniprot id: B2IK19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

395963:BIND RS14080
gene id: 395963:BIND_RS14080
uniprot id: B2IJY6
names: Similarity
messages: Belongs to the thioredoxin family.

395963:BIND RS04965
gene id: 395963:BIND_RS04965
uniprot id: B2II39
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS08325
gene id: 395963:BIND_RS08325
uniprot id: B2IC18
names: Similarity
messages: Belongs to the ros/MucR family.

395963:BIND RS03550
gene id: 395963:BIND_RS03550
uniprot id: B2IGF9
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS03330
gene id: 395963:BIND_RS03330
uniprot id: B2IFT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395963:BIND RS17840
gene id: 395963:BIND_RS17840
uniprot id: B2IFG7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

395963:BIND RS06090
gene id: 395963:BIND_RS06090
uniprot id: B2IJ78
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS07265
gene id: 395963:BIND_RS07265
uniprot id: B2IKN1
names: Similarity
messages: Belongs to the UPF0276 family.

395963:BIND RS04675
gene id: 395963:BIND_RS04675
uniprot id: B2IHP7
names: Similarity
messages: Belongs to the autoinducer synthase family.

395963:BIND RS15515
gene id: 395963:BIND_RS15515
uniprot id: B2IBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

395963:BIND RS00760
gene id: 395963:BIND_RS00760
uniprot id: B2IBT5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

395963:BIND RS11535
gene id: 395963:BIND_RS11535
uniprot id: B2IHB5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

395963:BIND RS06905
gene id: 395963:BIND_RS06905
uniprot id: B2IK68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

395963:BIND RS04475
gene id: 395963:BIND_RS04475
uniprot id: B2IHK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

395963:BIND RS03245
gene id: 395963:BIND_RS03245
uniprot id: B2IFR9
names: Similarity
messages: Belongs to the pyruvate kinase family.

395963:BIND RS15785
gene id: 395963:BIND_RS15785
uniprot id: B2IC82
names: Similarity
messages: Belongs to the BolA/IbaG family.

395963:BIND RS12275
gene id: 395963:BIND_RS12275
uniprot id: B2IHZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell inner membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

395963:BIND RS11390
gene id: 395963:BIND_RS11390
uniprot id: B2IH85
names: Function
messages: Multidrug efflux pump.

395963:BIND RS03560
gene id: 395963:BIND_RS03560
uniprot id: B2IGG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

395963:BIND RS00895
gene id: 395963:BIND_RS00895
uniprot id: B2IBW2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

395963:BIND RS14455
gene id: 395963:BIND_RS14455
uniprot id: B2IKF5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

395963:BIND RS01760
gene id: 395963:BIND_RS01760
uniprot id: B2IDE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

395963:BIND RS05280
gene id: 395963:BIND_RS05280
uniprot id: B2IIJ1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

395963:BIND RS15405
gene id: 395963:BIND_RS15405
uniprot id: B2IBH8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

395963:BIND RS08785
gene id: 395963:BIND_RS08785
uniprot id: B2ICT7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

395963:BIND RS03545
gene id: 395963:BIND_RS03545
uniprot id: B2IGF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

395963:BIND RS02860
gene id: 395963:BIND_RS02860
uniprot id: B2IF23
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

395963:BIND RS04740
gene id: 395963:BIND_RS04740
uniprot id: B2IHQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

395963:BIND RS00845
gene id: 395963:BIND_RS00845
uniprot id: B2IBV2
names: Similarity
messages: Belongs to the fructosamine kinase family.

395963:BIND RS08880
gene id: 395963:BIND_RS08880
uniprot id: B2ICV7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

395963:BIND RS10240
gene id: 395963:BIND_RS10240
uniprot id: B2IF83
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS16315
gene id: 395963:BIND_RS16315
uniprot id: B2ID12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

395963:BIND RS10325
gene id: 395963:BIND_RS10325
uniprot id: B2IFA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS05315
gene id: 395963:BIND_RS05315
uniprot id: B2IIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

395963:BIND RS10100
gene id: 395963:BIND_RS10100
uniprot id: B2IF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS02725
gene id: 395963:BIND_RS02725
uniprot id: B2IEZ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

395963:BIND RS16535
gene id: 395963:BIND_RS16535
uniprot id: B2ID53
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

395963:BIND RS04125
gene id: 395963:BIND_RS04125
uniprot id: B2IH47
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS09500
gene id: 395963:BIND_RS09500
uniprot id: B2IEA3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

395963:BIND RS05390
gene id: 395963:BIND_RS05390
uniprot id: B2IIL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

395963:BIND RS07300
gene id: 395963:BIND_RS07300
uniprot id: B2IKN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS00035
gene id: 395963:BIND_RS00035
uniprot id: B2IAW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

395963:BIND RS07205
gene id: 395963:BIND_RS07205
uniprot id: B2IKL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

395963:BIND RS16960
gene id: 395963:BIND_RS16960
uniprot id: B2IDW8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

395963:BIND RS05540
gene id: 395963:BIND_RS05540
uniprot id: B2IIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS08465
gene id: 395963:BIND_RS08465
uniprot id: B2IC46
names: Similarity
messages: Belongs to the peptidase S11 family.

395963:BIND RS16845
gene id: 395963:BIND_RS16845
uniprot id: B2IDU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

395963:BIND RS08760
gene id: 395963:BIND_RS08760
uniprot id: B2ICT2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

395963:BIND RS00275
gene id: 395963:BIND_RS00275
uniprot id: B2IB14
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS11440
gene id: 395963:BIND_RS11440
uniprot id: B2IH96
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS03030
gene id: 395963:BIND_RS03030
uniprot id: B2IFN5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS17000
gene id: 395963:BIND_RS17000
uniprot id: B2IDX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

395963:BIND RS06060
gene id: 395963:BIND_RS06060
uniprot id: B2IJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

395963:BIND RS05165
gene id: 395963:BIND_RS05165
uniprot id: B2II78
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

395963:BIND RS00400
gene id: 395963:BIND_RS00400
uniprot id: B2IB39
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

395963:BIND RS11775
gene id: 395963:BIND_RS11775
uniprot id: B2IHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

395963:BIND RS00510
gene id: 395963:BIND_RS00510
uniprot id: B2IBN7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

395963:BIND RS01680
gene id: 395963:BIND_RS01680
uniprot id: B2IDD3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

395963:BIND RS08885
gene id: 395963:BIND_RS08885
uniprot id: B2ICV8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

395963:BIND RS14465
gene id: 395963:BIND_RS14465
uniprot id: B2IKF7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

395963:BIND RS09680
gene id: 395963:BIND_RS09680
uniprot id: B2IED7
names: Similarity
messages: Belongs to the LOG family.

395963:BIND RS07720
gene id: 395963:BIND_RS07720
uniprot id: B2IB71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395963:BIND RS17805
gene id: 395963:BIND_RS17805
uniprot id: B2IFG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

395963:BIND RS02805
gene id: 395963:BIND_RS02805
uniprot id: B2IF12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS14015
gene id: 395963:BIND_RS14015
uniprot id: B2IJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

395963:BIND RS12065
gene id: 395963:BIND_RS12065
uniprot id: B2IHV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395963:BIND RS13510
gene id: 395963:BIND_RS13510
uniprot id: B2IJD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

395963:BIND RS07965
gene id: 395963:BIND_RS07965
uniprot id: B2IBB8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

395963:BIND RS03540
gene id: 395963:BIND_RS03540
uniprot id: B2IGF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

395963:BIND RS11405
gene id: 395963:BIND_RS11405
uniprot id: B2IH89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395963:BIND RS11185
gene id: 395963:BIND_RS11185
uniprot id: B2IGR8
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS14520
gene id: 395963:BIND_RS14520
uniprot id: B2IKG8
names: Similarity
messages: Belongs to the YggT family.

395963:BIND RS03165
gene id: 395963:BIND_RS03165
uniprot id: B2IFQ3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

395963:BIND RS06365
gene id: 395963:BIND_RS06365
uniprot id: B2IJM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

395963:BIND RS01700
gene id: 395963:BIND_RS01700
uniprot id: B2IDD7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS11850
gene id: 395963:BIND_RS11850
uniprot id: B2IHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

395963:BIND RS09305
gene id: 395963:BIND_RS09305
uniprot id: B2IDM7
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

395963:BIND RS09945
gene id: 395963:BIND_RS09945
uniprot id: B2IEI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

395963:BIND RS18080
gene id: 395963:BIND_RS18080
uniprot id: B2IG39
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

395963:BIND RS10910
gene id: 395963:BIND_RS10910
uniprot id: B2IGL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

395963:BIND RS06450
gene id: 395963:BIND_RS06450
uniprot id: B2IJP0
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Has an organic peroxide-dependent peroxidase activity.

395963:BIND RS08370
gene id: 395963:BIND_RS08370
uniprot id: B2IC27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

395963:BIND RS05045
gene id: 395963:BIND_RS05045
uniprot id: B2II55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

395963:BIND RS11670
gene id: 395963:BIND_RS11670
uniprot id: B2IHD6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

395963:BIND RS04995
gene id: 395963:BIND_RS04995
uniprot id: B2II45
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS12610
gene id: 395963:BIND_RS12610
uniprot id: B2IIE9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

395963:BIND RS00485
gene id: 395963:BIND_RS00485
uniprot id: B2IBN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

395963:BIND RS05795
gene id: 395963:BIND_RS05795
uniprot id: B2IJ20
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

395963:BIND RS11415
gene id: 395963:BIND_RS11415
uniprot id: B2IH91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

395963:BIND RS12070
gene id: 395963:BIND_RS12070
uniprot id: B2IHV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

395963:BIND RS01275
gene id: 395963:BIND_RS01275
uniprot id: B2ICM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

395963:BIND RS18580
gene id: 395963:BIND_RS18580
uniprot id: B2IGW0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

395963:BIND RS18440
gene id: 395963:BIND_RS18440
uniprot id: B2IGA5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

395963:BIND RS07540
gene id: 395963:BIND_RS07540
uniprot id: B2IKS9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS03170
gene id: 395963:BIND_RS03170
uniprot id: B2IFQ4
names: Similarity
messages: Belongs to the HIBADH-related family.

395963:BIND RS02760
gene id: 395963:BIND_RS02760
uniprot id: B2IF03
names: Similarity
messages: Belongs to the YkuD family.

395963:BIND RS00495
gene id: 395963:BIND_RS00495
uniprot id: B2IBN4
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

395963:BIND RS02795
gene id: 395963:BIND_RS02795
uniprot id: B2IF10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

395963:BIND RS02740
gene id: 395963:BIND_RS02740
uniprot id: B2IEZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

395963:BIND RS07005
gene id: 395963:BIND_RS07005
uniprot id: B2IK88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

395963:BIND RS10055
gene id: 395963:BIND_RS10055
uniprot id: B2IF45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

395963:BIND RS12855
gene id: 395963:BIND_RS12855
uniprot id: B2IIT5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

395963:BIND RS12910
gene id: 395963:BIND_RS12910
uniprot id: B2IIU6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

395963:BIND RS07355
gene id: 395963:BIND_RS07355
uniprot id: B2IKP9
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

395963:BIND RS06030
gene id: 395963:BIND_RS06030
uniprot id: B2IJ67
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

395963:BIND RS15255
gene id: 395963:BIND_RS15255
uniprot id: B2IBE9
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

395963:BIND RS18495
gene id: 395963:BIND_RS18495
uniprot id: B2IGB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

395963:BIND RS11005
gene id: 395963:BIND_RS11005
uniprot id: B2IGN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

395963:BIND RS14900
gene id: 395963:BIND_RS14900
uniprot id: B2IKY0
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS08250
gene id: 395963:BIND_RS08250
uniprot id: B2IC04
names: Similarity
messages: Belongs to the UPF0386 family.

395963:BIND RS18685
gene id: 395963:BIND_RS18685
uniprot id: B2IGY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

395963:BIND RS02335
gene id: 395963:BIND_RS02335
uniprot id: B2IE88
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

395963:BIND RS00240
gene id: 395963:BIND_RS00240
uniprot id: B2IB07
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

395963:BIND RS09440
gene id: 395963:BIND_RS09440
uniprot id: B2IDQ4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

395963:BIND RS13715
gene id: 395963:BIND_RS13715
uniprot id: B2IJH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

395963:BIND RS10540
gene id: 395963:BIND_RS10540
uniprot id: B2IFW9
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

395963:BIND RS08430
gene id: 395963:BIND_RS08430
uniprot id: B2IC39
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS10485
gene id: 395963:BIND_RS10485
uniprot id: B2IFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

395963:BIND RS12295
gene id: 395963:BIND_RS12295
uniprot id: B2IHZ4
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

395963:BIND RS12290
gene id: 395963:BIND_RS12290
uniprot id: B2IHZ3
names: Subcellular Location Annotation
messages: Cytoplasm

395963:BIND RS06880
gene id: 395963:BIND_RS06880
uniprot id: B2IK63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

395963:BIND RS11510
gene id: 395963:BIND_RS11510
uniprot id: B2IHB1
names: Similarity
messages: Belongs to the AHA1 family.

395963:BIND RS01235
gene id: 395963:BIND_RS01235
uniprot id: B2ICL4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

395963:BIND RS13670
gene id: 395963:BIND_RS13670
uniprot id: B2IJH0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

395963:BIND RS11525
gene id: 395963:BIND_RS11525
uniprot id: B2IHB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane

395963:BIND RS14130
gene id: 395963:BIND_RS14130
uniprot id: B2IJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

395963:BIND RS15290
gene id: 395963:BIND_RS15290
uniprot id: B2IBF6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

395963:BIND RS05380
gene id: 395963:BIND_RS05380
uniprot id: B2IIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS11430
gene id: 395963:BIND_RS11430
uniprot id: B2IH94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

395963:BIND RS10935
gene id: 395963:BIND_RS10935
uniprot id: B2IGM2
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.

395963:BIND RS04585
gene id: 395963:BIND_RS04585
uniprot id: B2IHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS09625
gene id: 395963:BIND_RS09625
uniprot id: B2IEC7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

395963:BIND RS02300
gene id: 395963:BIND_RS02300
uniprot id: B2IE81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

395963:BIND RS03730
gene id: 395963:BIND_RS03730
uniprot id: B2IGJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

395963:BIND RS08030
gene id: 395963:BIND_RS08030
uniprot id: B2IBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS12850
gene id: 395963:BIND_RS12850
uniprot id: B2IIT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alphaproteobacteria porin family.
messages: Cell outer membrane
messages: Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.
messages: Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.

395963:BIND RS05370
gene id: 395963:BIND_RS05370
uniprot id: B2IIK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

395963:BIND RS14445
gene id: 395963:BIND_RS14445
uniprot id: B2IKF3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

395963:BIND RS15805
gene id: 395963:BIND_RS15805
uniprot id: B2IC86
names: Similarity
messages: Belongs to the SAICAR synthetase family.

395963:BIND RS05855
gene id: 395963:BIND_RS05855
uniprot id: B2IJ32
names: Similarity
messages: Belongs to the peptidase A31 family.

395963:BIND RS09170
gene id: 395963:BIND_RS09170
uniprot id: B2IDK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

395963:BIND RS10405
gene id: 395963:BIND_RS10405
uniprot id: B2IFB7
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS11035
gene id: 395963:BIND_RS11035
uniprot id: B2IGP1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

395963:BIND RS01310
gene id: 395963:BIND_RS01310
uniprot id: B2ICM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

395963:BIND RS02400
gene id: 395963:BIND_RS02400
uniprot id: B2IET1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS02485
gene id: 395963:BIND_RS02485
uniprot id: B2IEV0
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

395963:BIND RS01365
gene id: 395963:BIND_RS01365
uniprot id: B2ICP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

395963:BIND RS06850
gene id: 395963:BIND_RS06850
uniprot id: B2IK57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

395963:BIND RS18135
gene id: 395963:BIND_RS18135
uniprot id: B2IG50
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS12025
gene id: 395963:BIND_RS12025
uniprot id: B2IHV0
names: Similarity
messages: Belongs to the SCO1/2 family.

395963:BIND RS01035
gene id: 395963:BIND_RS01035
uniprot id: B2ICH3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

395963:BIND RS05570
gene id: 395963:BIND_RS05570
uniprot id: B2IIP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

395963:BIND RS01090
gene id: 395963:BIND_RS01090
uniprot id: B2ICI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

395963:BIND RS02160
gene id: 395963:BIND_RS02160
uniprot id: B2IE55
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS01095
gene id: 395963:BIND_RS01095
uniprot id: B2ICI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

395963:BIND RS04420
gene id: 395963:BIND_RS04420
uniprot id: B2IHJ8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS07555
gene id: 395963:BIND_RS07555
uniprot id: B2IKT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

395963:BIND RS15740
gene id: 395963:BIND_RS15740
uniprot id: B2IC73
names: Caution
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS17775
gene id: 395963:BIND_RS17775
uniprot id: B2IFF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

395963:BIND RS11090
gene id: 395963:BIND_RS11090
uniprot id: B2IGQ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS07155
gene id: 395963:BIND_RS07155
uniprot id: B2IKL0
names: Similarity
messages: Belongs to the citrate synthase family.

395963:BIND RS06555
gene id: 395963:BIND_RS06555
uniprot id: B2IJR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

395963:BIND RS14675
gene id: 395963:BIND_RS14675
uniprot id: B2IKJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS16820
gene id: 395963:BIND_RS16820
uniprot id: B2IDU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

395963:BIND RS12050
gene id: 395963:BIND_RS12050
uniprot id: B2IHV5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

395963:BIND RS00765
gene id: 395963:BIND_RS00765
uniprot id: B2IBT6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

395963:BIND RS04110
gene id: 395963:BIND_RS04110
uniprot id: B2IH44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.

395963:BIND RS01935
gene id: 395963:BIND_RS01935
uniprot id: B2IE10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

395963:BIND RS16550
gene id: 395963:BIND_RS16550
uniprot id: B2ID56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

395963:BIND RS03910
gene id: 395963:BIND_RS03910
uniprot id: B2IH03
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

395963:BIND RS06900
gene id: 395963:BIND_RS06900
uniprot id: B2IK67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

395963:BIND RS04595
gene id: 395963:BIND_RS04595
uniprot id: B2IHN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

395963:BIND RS11555
gene id: 395963:BIND_RS11555
uniprot id: B2IHB8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

395963:BIND RS18195
gene id: 395963:BIND_RS18195
uniprot id: B2IG61
names: Similarity
messages: Belongs to the UPF0235 family.

395963:BIND RS16740
gene id: 395963:BIND_RS16740
uniprot id: B2IDS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

395963:BIND RS11990
gene id: 395963:BIND_RS11990
uniprot id: B2IHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

395963:BIND RS11150
gene id: 395963:BIND_RS11150
uniprot id: B2IGR2
names: Similarity
messages: Belongs to the XFP family.

395963:BIND RS08115
gene id: 395963:BIND_RS08115
uniprot id: B2IBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

395963:BIND RS17615
gene id: 395963:BIND_RS17615
uniprot id: B2IFC3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

395963:BIND RS15780
gene id: 395963:BIND_RS15780
uniprot id: B2IC81
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

395963:BIND RS12640
gene id: 395963:BIND_RS12640
uniprot id: B2IIF5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

395963:BIND RS13105
gene id: 395963:BIND_RS13105
uniprot id: B2IIX5
names: Similarity
messages: Belongs to the MlaA family.

395963:BIND RS08120
gene id: 395963:BIND_RS08120
uniprot id: B2IBX6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

395963:BIND RS00535
gene id: 395963:BIND_RS00535
uniprot id: B2IBP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

395963:BIND RS14415
gene id: 395963:BIND_RS14415
uniprot id: B2IKE7
names: Similarity
messages: Belongs to the pyruvate kinase family.

395963:BIND RS12365
gene id: 395963:BIND_RS12365
uniprot id: B2IIA0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

395963:BIND RS17040
gene id: 395963:BIND_RS17040
uniprot id: B2IDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS03155
gene id: 395963:BIND_RS03155
uniprot id: B2IFQ1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

395963:BIND RS15920
gene id: 395963:BIND_RS15920
uniprot id: B2ICB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

395963:BIND RS06735
gene id: 395963:BIND_RS06735
uniprot id: B2IK35
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

395963:BIND RS10915
gene id: 395963:BIND_RS10915
uniprot id: B2IGL7
names: Similarity
messages: Belongs to the CutA family.

395963:BIND RS11650
gene id: 395963:BIND_RS11650
uniprot id: B2IHD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

395963:BIND RS03570
gene id: 395963:BIND_RS03570
uniprot id: B2IGG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

395963:BIND RS01400
gene id: 395963:BIND_RS01400
uniprot id: B2ID74
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

395963:BIND RS01510
gene id: 395963:BIND_RS01510
uniprot id: B2ID94
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS00055
gene id: 395963:BIND_RS00055
uniprot id: B2IAW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS03585
gene id: 395963:BIND_RS03585
uniprot id: B2IGG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

395963:BIND RS08245
gene id: 395963:BIND_RS08245
uniprot id: B2IC03
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

395963:BIND RS11755
gene id: 395963:BIND_RS11755
uniprot id: B2IHF3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell inner membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

395963:BIND RS17925
gene id: 395963:BIND_RS17925
uniprot id: B2IFI8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

395963:BIND RS05245
gene id: 395963:BIND_RS05245
uniprot id: B2III4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

395963:BIND RS16685
gene id: 395963:BIND_RS16685
uniprot id: B2IDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

395963:BIND RS12355
gene id: 395963:BIND_RS12355
uniprot id: B2II98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

395963:BIND RS05215
gene id: 395963:BIND_RS05215
uniprot id: B2IIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

395963:BIND RS13995
gene id: 395963:BIND_RS13995
uniprot id: B2IJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

395963:BIND RS01645
gene id: 395963:BIND_RS01645
uniprot id: B2IDC6
names: Similarity
messages: Belongs to the YkuD family.

395963:BIND RS00265
gene id: 395963:BIND_RS00265
uniprot id: B2IB12
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

395963:BIND RS12160
gene id: 395963:BIND_RS12160
uniprot id: B2IHX4
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS10300
gene id: 395963:BIND_RS10300
uniprot id: B2IF97
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

395963:BIND RS14680
gene id: 395963:BIND_RS14680
uniprot id: B2IKJ9
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

395963:BIND RS17695
gene id: 395963:BIND_RS17695
uniprot id: B2IFD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

395963:BIND RS01405
gene id: 395963:BIND_RS01405
uniprot id: B2ID75
names: Subcellular Location Annotation
messages: Cell inner membrane

395963:BIND RS10165
gene id: 395963:BIND_RS10165
uniprot id: B2IF68
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

395963:BIND RS10710
gene id: 395963:BIND_RS10710
uniprot id: B2IG00
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS11250
gene id: 395963:BIND_RS11250
uniprot id: B2IGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

395963:BIND RS06175
gene id: 395963:BIND_RS06175
uniprot id: B2IJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

395963:BIND RS10860
gene id: 395963:BIND_RS10860
uniprot id: B2IG29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

395963:BIND RS16925
gene id: 395963:BIND_RS16925
uniprot id: B2IDW2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

395963:BIND RS05080
gene id: 395963:BIND_RS05080
uniprot id: B2II62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

395963:BIND RS14095
gene id: 395963:BIND_RS14095
uniprot id: B2IJY9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

395963:BIND RS07455
gene id: 395963:BIND_RS07455
uniprot id: B2IKR5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS15170
gene id: 395963:BIND_RS15170
uniprot id: B2IL27
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS00020
gene id: 395963:BIND_RS00020
uniprot id: B2IAW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

395963:BIND RS19640
gene id: 395963:BIND_RS19640
uniprot id: B2ILK2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

395963:BIND RS02410
gene id: 395963:BIND_RS02410
uniprot id: B2IET3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

395963:BIND RS06180
gene id: 395963:BIND_RS06180
uniprot id: B2IJI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.
messages: In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.

395963:BIND RS04550
gene id: 395963:BIND_RS04550
uniprot id: B2IHM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

395963:BIND RS01165
gene id: 395963:BIND_RS01165
uniprot id: B2ICK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

395963:BIND RS14170
gene id: 395963:BIND_RS14170
uniprot id: B2IK04
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

395963:BIND RS13475
gene id: 395963:BIND_RS13475
uniprot id: B2IJC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

395963:BIND RS02500
gene id: 395963:BIND_RS02500
uniprot id: B2IEV3
names: Function
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.

395963:BIND RS11905
gene id: 395963:BIND_RS11905
uniprot id: B2IHS5
names: Similarity
messages: Belongs to the GST superfamily.

395963:BIND RS04225
gene id: 395963:BIND_RS04225
uniprot id: B2IH69
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

395963:BIND RS01040
gene id: 395963:BIND_RS01040
uniprot id: B2ICH4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

395963:BIND RS04525
gene id: 395963:BIND_RS04525
uniprot id: B2IHL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

395963:BIND RS18565
gene id: 395963:BIND_RS18565
uniprot id: B2IGV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

395963:BIND RS05840
gene id: 395963:BIND_RS05840
uniprot id: B2IJ29
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

395963:BIND RS17600
gene id: 395963:BIND_RS17600
uniprot id: B2IFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

395963:BIND RS00875
gene id: 395963:BIND_RS00875
uniprot id: B2IBV8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS07380
gene id: 395963:BIND_RS07380
uniprot id: B2IKQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS03750
gene id: 395963:BIND_RS03750
uniprot id: B2IGK1
names: Similarity
messages: Belongs to the GcvT family.

395963:BIND RS08905
gene id: 395963:BIND_RS08905
uniprot id: B2ICW2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

395963:BIND RS14350
gene id: 395963:BIND_RS14350
uniprot id: B2IKD5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

395963:BIND RS00545
gene id: 395963:BIND_RS00545
uniprot id: B2IBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

395963:BIND RS18395
gene id: 395963:BIND_RS18395
uniprot id: B2IG96
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

395963:BIND RS09690
gene id: 395963:BIND_RS09690
uniprot id: B2IED9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

395963:BIND RS05580
gene id: 395963:BIND_RS05580
uniprot id: B2IIP8
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS00260
gene id: 395963:BIND_RS00260
uniprot id: B2IB11
names: Similarity
messages: Belongs to the YkuD family.

395963:BIND RS06865
gene id: 395963:BIND_RS06865
uniprot id: B2IEH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

395963:BIND RS06995
gene id: 395963:BIND_RS06995
uniprot id: B2IK86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

395963:BIND RS03695
gene id: 395963:BIND_RS03695
uniprot id: B2IGI9
names: Similarity
messages: Belongs to the peptidase M16 family.

395963:BIND RS13800
gene id: 395963:BIND_RS13800
uniprot id: B2IJT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

395963:BIND RS03440
gene id: 395963:BIND_RS03440
uniprot id: B2IGD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

395963:BIND RS07445
gene id: 395963:BIND_RS07445
uniprot id: B2IKR4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

395963:BIND RS02320
gene id: 395963:BIND_RS02320
uniprot id: B2IE85
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

395963:BIND RS13010
gene id: 395963:BIND_RS13010
uniprot id: B2IIW0
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS01650
gene id: 395963:BIND_RS01650
uniprot id: B2IDC7
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

395963:BIND RS10985
gene id: 395963:BIND_RS10985
uniprot id: B2IGN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

395963:BIND RS06570
gene id: 395963:BIND_RS06570
uniprot id: B2IJR5
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS12745
gene id: 395963:BIND_RS12745
uniprot id: B2IIH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

395963:BIND RS07200
gene id: 395963:BIND_RS07200
uniprot id: B2IKL7
names: Similarity
messages: Belongs to the TrpC family.

395963:BIND RS08875
gene id: 395963:BIND_RS08875
uniprot id: B2ICV6
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

395963:BIND RS06705
gene id: 395963:BIND_RS06705
uniprot id: B2IK29
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

395963:BIND RS16785
gene id: 395963:BIND_RS16785
uniprot id: B2IDT4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

395963:BIND RS01050
gene id: 395963:BIND_RS01050
uniprot id: B2ICH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

395963:BIND RS06860
gene id: 395963:BIND_RS06860
uniprot id: B2IK59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

395963:BIND RS00920
gene id: 395963:BIND_RS00920
uniprot id: B2IBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.

395963:BIND RS05545
gene id: 395963:BIND_RS05545
uniprot id: B2IIP1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

395963:BIND RS01130
gene id: 395963:BIND_RS01130
uniprot id: B2ICJ3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

395963:BIND RS15490
gene id: 395963:BIND_RS15490
uniprot id: B2IBJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

395963:BIND RS10335
gene id: 395963:BIND_RS10335
uniprot id: B2IFA4
names: Function
names: Similarity
messages: Belongs to the CowN family.
messages: Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.

395963:BIND RS15665
gene id: 395963:BIND_RS15665
uniprot id: B2IBM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

395963:BIND RS09725
gene id: 395963:BIND_RS09725
uniprot id: B2IEE7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS03725
gene id: 395963:BIND_RS03725
uniprot id: B2IGJ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

395963:BIND RS06815
gene id: 395963:BIND_RS06815
uniprot id: B2IK50
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

395963:BIND RS03480
gene id: 395963:BIND_RS03480
uniprot id: B2IGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS15710
gene id: 395963:BIND_RS15710
uniprot id: B2IC66
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

395963:BIND RS02145
gene id: 395963:BIND_RS02145
uniprot id: B2IE52
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

395963:BIND RS00800
gene id: 395963:BIND_RS00800
uniprot id: B2IBU3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

395963:BIND RS01945
gene id: 395963:BIND_RS01945
uniprot id: B2IE12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

395963:BIND RS19775
gene id: 395963:BIND_RS19775
uniprot id: B2ILM6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

395963:BIND RS00790
gene id: 395963:BIND_RS00790
uniprot id: B2IBU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

395963:BIND RS11945
gene id: 395963:BIND_RS11945
uniprot id: B2IHT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

395963:BIND RS00995
gene id: 395963:BIND_RS00995
uniprot id: B2ICG6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

395963:BIND RS04205
gene id: 395963:BIND_RS04205
uniprot id: B2IH64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

395963:BIND RS00840
gene id: 395963:BIND_RS00840
uniprot id: B2IBV1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

395963:BIND RS12060
gene id: 395963:BIND_RS12060
uniprot id: B2IHV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

395963:BIND RS14235
gene id: 395963:BIND_RS14235
uniprot id: B2IK13
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS13990
gene id: 395963:BIND_RS13990
uniprot id: B2IJX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

395963:BIND RS02515
gene id: 395963:BIND_RS02515
uniprot id: B2IEV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

395963:BIND RS07160
gene id: 395963:BIND_RS07160
uniprot id: B2IKL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

395963:BIND RS11815
gene id: 395963:BIND_RS11815
uniprot id: B2IHG5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

395963:BIND RS15435
gene id: 395963:BIND_RS15435
uniprot id: B2IBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

395963:BIND RS12405
gene id: 395963:BIND_RS12405
uniprot id: B2IIA8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

395963:BIND RS08405
gene id: 395963:BIND_RS08405
uniprot id: B2IC34
names: Similarity
messages: Belongs to the peptidase C15 family.

395963:BIND RS02525
gene id: 395963:BIND_RS02525
uniprot id: B2IEV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

395963:BIND RS14050
gene id: 395963:BIND_RS14050
uniprot id: B2IJY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS06055
gene id: 395963:BIND_RS06055
uniprot id: B2IJ71
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

395963:BIND RS07045
gene id: 395963:BIND_RS07045
uniprot id: B2IK96
names: Similarity
messages: Belongs to the FBPase class 2 family.

395963:BIND RS16880
gene id: 395963:BIND_RS16880
uniprot id: B2IDV3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

395963:BIND RS20215
gene id: 395963:BIND_RS20215
uniprot id: B2IJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

395963:BIND RS01410
gene id: 395963:BIND_RS01410
uniprot id: B2ID76
names: Similarity
messages: Belongs to the NadC/ModD family.

395963:BIND RS05020
gene id: 395963:BIND_RS05020
uniprot id: B2II50
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

395963:BIND RS10890
gene id: 395963:BIND_RS10890
uniprot id: B2IGL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

395963:BIND RS00455
gene id: 395963:BIND_RS00455
uniprot id: B2IB45
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395963:BIND RS03190
gene id: 395963:BIND_RS03190
uniprot id: B2IFQ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS09560
gene id: 395963:BIND_RS09560
uniprot id: B2IEB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

395963:BIND RS15790
gene id: 395963:BIND_RS15790
uniprot id: B2IC83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

395963:BIND RS05740
gene id: 395963:BIND_RS05740
uniprot id: B2IJ10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell inner membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

395963:BIND RS14810
gene id: 395963:BIND_RS14810
uniprot id: B2IKW4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

395963:BIND RS03970
gene id: 395963:BIND_RS03970
uniprot id: B2IH15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

395963:BIND RS04045
gene id: 395963:BIND_RS04045
uniprot id: B2IH31
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

395963:BIND RS02105
gene id: 395963:BIND_RS02105
uniprot id: B2IE44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

395963:BIND RS13530
gene id: 395963:BIND_RS13530
uniprot id: B2IJE2
names: Similarity
messages: Belongs to the peptidase S58 family.

395963:BIND RS15510
gene id: 395963:BIND_RS15510
uniprot id: B2IBJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

395963:BIND RS11960
gene id: 395963:BIND_RS11960
uniprot id: B2IHT6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS05910
gene id: 395963:BIND_RS05910
uniprot id: B2IJ43
names: Similarity
messages: Belongs to the HypE family.

395963:BIND RS08690
gene id: 395963:BIND_RS08690
uniprot id: B2ICS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

395963:BIND RS13325
gene id: 395963:BIND_RS13325
uniprot id: B2IJA2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

395963:BIND RS07690
gene id: 395963:BIND_RS07690
uniprot id: B2IB65
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS02340
gene id: 395963:BIND_RS02340
uniprot id: B2IE89
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

395963:BIND RS02965
gene id: 395963:BIND_RS02965
uniprot id: B2IFM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

395963:BIND RS15955
gene id: 395963:BIND_RS15955
uniprot id: B2ICB6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

395963:BIND RS10680
gene id: 395963:BIND_RS10680
uniprot id: B2IFZ4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS08345
gene id: 395963:BIND_RS08345
uniprot id: B2IC22
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

395963:BIND RS01770
gene id: 395963:BIND_RS01770
uniprot id: B2IDF1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS12780
gene id: 395963:BIND_RS12780
uniprot id: B2IIS0
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS02750
gene id: 395963:BIND_RS02750
uniprot id: B2IF01
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

395963:BIND RS12730
gene id: 395963:BIND_RS12730
uniprot id: B2IIG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS08050
gene id: 395963:BIND_RS08050
uniprot id: B2IBE0
names: Similarity
messages: Belongs to the peptidase A24 family.

395963:BIND RS08145
gene id: 395963:BIND_RS08145
uniprot id: B2IBY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

395963:BIND RS18245
gene id: 395963:BIND_RS18245
uniprot id: B2IG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

395963:BIND RS06505
gene id: 395963:BIND_RS06505
uniprot id: B2IJQ1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

395963:BIND RS08420
gene id: 395963:BIND_RS08420
uniprot id: B2IC37
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

395963:BIND RS04785
gene id: 395963:BIND_RS04785
uniprot id: B2II05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Membrane

395963:BIND RS17995
gene id: 395963:BIND_RS17995
uniprot id: B2IFK0
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

395963:BIND RS06000
gene id: 395963:BIND_RS06000
uniprot id: B2IJ61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS17295
gene id: 395963:BIND_RS17295
uniprot id: B2IEM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

395963:BIND RS08705
gene id: 395963:BIND_RS08705
uniprot id: B2ICS3
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS04535
gene id: 395963:BIND_RS04535
uniprot id: B2IHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

395963:BIND RS12445
gene id: 395963:BIND_RS12445
uniprot id: B2IIB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

395963:BIND RS02480
gene id: 395963:BIND_RS02480
uniprot id: B2IEU9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

395963:BIND RS08240
gene id: 395963:BIND_RS08240
uniprot id: B2IC02
names: Similarity
messages: Belongs to the UPF0260 family.

395963:BIND RS08495
gene id: 395963:BIND_RS08495
uniprot id: B2IC52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

395963:BIND RS06890
gene id: 395963:BIND_RS06890
uniprot id: B2IK65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

395963:BIND RS16445
gene id: 395963:BIND_RS16445
uniprot id: B2ID37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

395963:BIND RS03755
gene id: 395963:BIND_RS03755
uniprot id: B2IGK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

395963:BIND RS15595
gene id: 395963:BIND_RS15595
uniprot id: B2IBL4
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS04725
gene id: 395963:BIND_RS04725
uniprot id: B2IHQ8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

395963:BIND RS00710
gene id: 395963:BIND_RS00710
uniprot id: B2IBS6
names: Similarity
messages: Belongs to the Dps family.

395963:BIND RS02165
gene id: 395963:BIND_RS02165
uniprot id: B2IE56
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

395963:BIND RS12320
gene id: 395963:BIND_RS12320
uniprot id: B2II91
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS17915
gene id: 395963:BIND_RS17915
uniprot id: B2IFI6
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS17205
gene id: 395963:BIND_RS17205
uniprot id: B2IEK5
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS10855
gene id: 395963:BIND_RS10855
uniprot id: B2IG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

395963:BIND RS04520
gene id: 395963:BIND_RS04520
uniprot id: B2IHL7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

395963:BIND RS03485
gene id: 395963:BIND_RS03485
uniprot id: B2IGE2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

395963:BIND RS12805
gene id: 395963:BIND_RS12805
uniprot id: B2IIS5
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS05055
gene id: 395963:BIND_RS05055
uniprot id: B2II57
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

395963:BIND RS18435
gene id: 395963:BIND_RS18435
uniprot id: B2IGA4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

395963:BIND RS01880
gene id: 395963:BIND_RS01880
uniprot id: B2IDC2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

395963:BIND RS00105
gene id: 395963:BIND_RS00105
uniprot id: B2IAX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

395963:BIND RS05155
gene id: 395963:BIND_RS05155
uniprot id: B2II76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

395963:BIND RS07650
gene id: 395963:BIND_RS07650
uniprot id: B2IB57
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

395963:BIND RS13860
gene id: 395963:BIND_RS13860
uniprot id: B2IJU4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

395963:BIND RS12775
gene id: 395963:BIND_RS12775
uniprot id: B2IIR9
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

395963:BIND RS13665
gene id: 395963:BIND_RS13665
uniprot id: B2IJG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

395963:BIND RS03510
gene id: 395963:BIND_RS03510
uniprot id: B2IGF1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

395963:BIND RS05800
gene id: 395963:BIND_RS05800
uniprot id: B2IJ21
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

395963:BIND RS15605
gene id: 395963:BIND_RS15605
uniprot id: B2IBL6
names: Similarity
messages: Belongs to the IlvD/Edd family.

395963:BIND RS04350
gene id: 395963:BIND_RS04350
uniprot id: B2IHI4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

395963:BIND RS06770
gene id: 395963:BIND_RS06770
uniprot id: B2IK42
names: Subcellular Location Annotation
messages: Membrane

395963:BIND RS02530
gene id: 395963:BIND_RS02530
uniprot id: B2IEV9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

395963:BIND RS03965
gene id: 395963:BIND_RS03965
uniprot id: B2IH14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

395963:BIND RS13525
gene id: 395963:BIND_RS13525
uniprot id: B2IJE1
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

395963:BIND RS00665
gene id: 395963:BIND_RS00665
uniprot id: B2IBR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

395963:BIND RS06560
gene id: 395963:BIND_RS06560
uniprot id: B2IJR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

395963:BIND RS02875
gene id: 395963:BIND_RS02875
uniprot id: B2IEU4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

395963:BIND RS18145
gene id: 395963:BIND_RS18145
uniprot id: B2IG52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS09700
gene id: 395963:BIND_RS09700
uniprot id: B2IEE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

395963:BIND RS03655
gene id: 395963:BIND_RS03655
uniprot id: B2IGI1
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

395963:BIND RS08800
gene id: 395963:BIND_RS08800
uniprot id: B2ICU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

395963:BIND RS07075
gene id: 395963:BIND_RS07075
uniprot id: B2IKA2
names: Similarity
messages: Belongs to the YciI family.

395963:BIND RS06535
gene id: 395963:BIND_RS06535
uniprot id: B2IJQ7
names: Similarity
messages: Belongs to the UPF0145 family.

395963:BIND RS06965
gene id: 395963:BIND_RS06965
uniprot id: B2IK80
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

395963:BIND RS01305
gene id: 395963:BIND_RS01305
uniprot id: B2ICM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

395963:BIND RS00425
gene id: 395963:BIND_RS00425
uniprot id: B2IB44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

395963:BIND RS10665
gene id: 395963:BIND_RS10665
uniprot id: B2IFZ1
names: Similarity
messages: Belongs to the thioredoxin family.

395963:BIND RS15830
gene id: 395963:BIND_RS15830
uniprot id: B2IC91
names: Activity Regulation
names: Caution
names: Domain
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

395963:BIND RS16515
gene id: 395963:BIND_RS16515
uniprot id: B2ID49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

395963:BIND RS02230
gene id: 395963:BIND_RS02230
uniprot id: B2IE68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

395963:BIND RS18015
gene id: 395963:BIND_RS18015
uniprot id: B2IFK5
names: Similarity
messages: Belongs to the cysteine dioxygenase family.