394503:CCEL RS12275
gene id: 394503:CCEL_RS12275
uniprot id: B8I5L6
names: Similarity
messages: Belongs to the class-I fumarase family.

394503:CCEL RS04520
gene id: 394503:CCEL_RS04520
uniprot id: B8I8M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS14475
gene id: 394503:CCEL_RS14475
uniprot id: B8I872
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS02255
gene id: 394503:CCEL_RS02255
uniprot id: B8I6D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

394503:CCEL RS07910
gene id: 394503:CCEL_RS07910
uniprot id: B8I2C5
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

394503:CCEL RS07055
gene id: 394503:CCEL_RS07055
uniprot id: B8I1F8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

394503:CCEL RS12260
gene id: 394503:CCEL_RS12260
uniprot id: B8I5L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

394503:CCEL RS03915
gene id: 394503:CCEL_RS03915
uniprot id: B8I7Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

394503:CCEL RS09645
gene id: 394503:CCEL_RS09645
uniprot id: B8I3B0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

394503:CCEL RS15025
gene id: 394503:CCEL_RS15025
uniprot id: B8I8U9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

394503:CCEL RS00640
gene id: 394503:CCEL_RS00640
uniprot id: B8I4G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

394503:CCEL RS11480
gene id: 394503:CCEL_RS11480
uniprot id: B8I4V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).
messages: Monomer.

394503:CCEL RS07295
gene id: 394503:CCEL_RS07295
uniprot id: B8I1X5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

394503:CCEL RS17455
gene id: 394503:CCEL_RS17455
uniprot id: B8I2A3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

394503:CCEL RS11510
gene id: 394503:CCEL_RS11510
uniprot id: B8I4W1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS09875
gene id: 394503:CCEL_RS09875
uniprot id: B8I3F5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS12410
gene id: 394503:CCEL_RS12410
uniprot id: B8I614
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

394503:CCEL RS03075
gene id: 394503:CCEL_RS03075
uniprot id: B8I762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

394503:CCEL RS02380
gene id: 394503:CCEL_RS02380
uniprot id: B8I6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

394503:CCEL RS09380
gene id: 394503:CCEL_RS09380
uniprot id: B8I359
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

394503:CCEL RS06580
gene id: 394503:CCEL_RS06580
uniprot id: B8I0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

394503:CCEL RS14660
gene id: 394503:CCEL_RS14660
uniprot id: B8I8A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

394503:CCEL RS16350
gene id: 394503:CCEL_RS16350
uniprot id: B8I0Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS14615
gene id: 394503:CCEL_RS14615
uniprot id: B8I895
names: Subcellular Location Annotation
messages: Cytoplasm

394503:CCEL RS14640
gene id: 394503:CCEL_RS14640
uniprot id: B8I8A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

394503:CCEL RS01435
gene id: 394503:CCEL_RS01435
uniprot id: B8I594
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

394503:CCEL RS10965
gene id: 394503:CCEL_RS10965
uniprot id: B8I480
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

394503:CCEL RS05410
gene id: 394503:CCEL_RS05410
uniprot id: B8HZT7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS15080
gene id: 394503:CCEL_RS15080
uniprot id: B8I8V7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS07370
gene id: 394503:CCEL_RS07370
uniprot id: B8I1Z0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

394503:CCEL RS08515
gene id: 394503:CCEL_RS08515
uniprot id: B8I2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

394503:CCEL RS00705
gene id: 394503:CCEL_RS00705
uniprot id: B8I4H4
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

394503:CCEL RS02325
gene id: 394503:CCEL_RS02325
uniprot id: B8I6F1
names: Similarity
messages: Belongs to the ribF family.

394503:CCEL RS13510
gene id: 394503:CCEL_RS13510
uniprot id: B8I704
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

394503:CCEL RS07730
gene id: 394503:CCEL_RS07730
uniprot id: B8I258
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusB family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

394503:CCEL RS05020
gene id: 394503:CCEL_RS05020
uniprot id: B8I9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS02655
gene id: 394503:CCEL_RS02655
uniprot id: B8I6L5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

394503:CCEL RS08795
gene id: 394503:CCEL_RS08795
uniprot id: B8I2V1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

394503:CCEL RS03455
gene id: 394503:CCEL_RS03455
uniprot id: B8I7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

394503:CCEL RS08825
gene id: 394503:CCEL_RS08825
uniprot id: B8I2V7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

394503:CCEL RS00485
gene id: 394503:CCEL_RS00485
uniprot id: B8I4C8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

394503:CCEL RS11780
gene id: 394503:CCEL_RS11780
uniprot id: B8I5D1
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

394503:CCEL RS01225
gene id: 394503:CCEL_RS01225
uniprot id: B8I551
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

394503:CCEL RS03095
gene id: 394503:CCEL_RS03095
uniprot id: B8I766
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

394503:CCEL RS03415
gene id: 394503:CCEL_RS03415
uniprot id: B8I7C7
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.

394503:CCEL RS12390
gene id: 394503:CCEL_RS12390
uniprot id: B8I610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS06340
gene id: 394503:CCEL_RS06340
uniprot id: B8I0P6
names: Similarity
messages: Belongs to the DapA family.

394503:CCEL RS00550
gene id: 394503:CCEL_RS00550
uniprot id: B8I4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

394503:CCEL RS07835
gene id: 394503:CCEL_RS07835
uniprot id: B8I277
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

394503:CCEL RS02835
gene id: 394503:CCEL_RS02835
uniprot id: B8I719
names: Similarity
messages: Belongs to the glutamine synthetase family.

394503:CCEL RS07285
gene id: 394503:CCEL_RS07285
uniprot id: B8I1X3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS11290
gene id: 394503:CCEL_RS11290
uniprot id: B8I4S1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

394503:CCEL RS05135
gene id: 394503:CCEL_RS05135
uniprot id: B8I9C4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS08685
gene id: 394503:CCEL_RS08685
uniprot id: B8I2T0
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

394503:CCEL RS05295
gene id: 394503:CCEL_RS05295
uniprot id: B8I9F4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

394503:CCEL RS03870
gene id: 394503:CCEL_RS03870
uniprot id: B8I7Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

394503:CCEL RS15585
gene id: 394503:CCEL_RS15585
uniprot id: B8I066
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

394503:CCEL RS15085
gene id: 394503:CCEL_RS15085
uniprot id: B8I8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS15565
gene id: 394503:CCEL_RS15565
uniprot id: B8I062
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

394503:CCEL RS06790
gene id: 394503:CCEL_RS06790
uniprot id: B8I1A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

394503:CCEL RS13325
gene id: 394503:CCEL_RS13325
uniprot id: B8I6X0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

394503:CCEL RS05180
gene id: 394503:CCEL_RS05180
uniprot id: B8I9D3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS05930
gene id: 394503:CCEL_RS05930
uniprot id: B8I040
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS11500
gene id: 394503:CCEL_RS11500
uniprot id: B8I4V9
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS06375
gene id: 394503:CCEL_RS06375
uniprot id: B8I0Q2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

394503:CCEL RS01515
gene id: 394503:CCEL_RS01515
uniprot id: B8I5B0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

394503:CCEL RS03710
gene id: 394503:CCEL_RS03710
uniprot id: P37700
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
messages: The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.

394503:CCEL RS14625
gene id: 394503:CCEL_RS14625
uniprot id: B8I897
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

394503:CCEL RS12580
gene id: 394503:CCEL_RS12580
uniprot id: B8I648
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS03040
gene id: 394503:CCEL_RS03040
uniprot id: B8I755
names: Similarity
messages: Belongs to the YggT family.

394503:CCEL RS00710
gene id: 394503:CCEL_RS00710
uniprot id: B8I4H5
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

394503:CCEL RS04860
gene id: 394503:CCEL_RS04860
uniprot id: B8I969
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS06955
gene id: 394503:CCEL_RS06955
uniprot id: B8I1D9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

394503:CCEL RS12990
gene id: 394503:CCEL_RS12990
uniprot id: B8I6Q4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

394503:CCEL RS16865
gene id: 394503:CCEL_RS16865
uniprot id: B8I1L7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

394503:CCEL RS06045
gene id: 394503:CCEL_RS06045
uniprot id: B8I0I7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS17275
gene id: 394503:CCEL_RS17275
uniprot id: B8I1U4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS00750
gene id: 394503:CCEL_RS00750
uniprot id: B8I4I3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS03575
gene id: 394503:CCEL_RS03575
uniprot id: B8I7S5
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

394503:CCEL RS02670
gene id: 394503:CCEL_RS02670
uniprot id: B8I6L8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

394503:CCEL RS01180
gene id: 394503:CCEL_RS01180
uniprot id: B8I541
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

394503:CCEL RS13425
gene id: 394503:CCEL_RS13425
uniprot id: B8I6Y9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS00675
gene id: 394503:CCEL_RS00675
uniprot id: B8I4G8
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

394503:CCEL RS03895
gene id: 394503:CCEL_RS03895
uniprot id: B8I7Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

394503:CCEL RS11570
gene id: 394503:CCEL_RS11570
uniprot id: B8I4X3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

394503:CCEL RS01895
gene id: 394503:CCEL_RS01895
uniprot id: B8I5U9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

394503:CCEL RS15130
gene id: 394503:CCEL_RS15130
uniprot id: B8I8W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS03715
gene id: 394503:CCEL_RS03715
uniprot id: B8I7V4
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

394503:CCEL RS12595
gene id: 394503:CCEL_RS12595
uniprot id: B8I651
names: Similarity
messages: Belongs to the DEAD box helicase family.

394503:CCEL RS08450
gene id: 394503:CCEL_RS08450
uniprot id: B8I2N3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS14835
gene id: 394503:CCEL_RS14835
uniprot id: B8I8D9
names: Similarity
messages: Belongs to the PemK/MazF family.

394503:CCEL RS09735
gene id: 394503:CCEL_RS09735
uniprot id: B8I3C8
names: Similarity
messages: Belongs to the peptidase M24B family.

394503:CCEL RS17590
gene id: 394503:CCEL_RS17590
uniprot id: B8I8J9
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

394503:CCEL RS16705
gene id: 394503:CCEL_RS16705
uniprot id: B8I164
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

394503:CCEL RS06165
gene id: 394503:CCEL_RS06165
uniprot id: B8I0L1
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

394503:CCEL RS09520
gene id: 394503:CCEL_RS09520
uniprot id: B8I385
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

394503:CCEL RS12970
gene id: 394503:CCEL_RS12970
uniprot id: B8I6Q0
names: Similarity
messages: Belongs to the UPF0758 family.

394503:CCEL RS05470
gene id: 394503:CCEL_RS05470
uniprot id: B8HZV0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

394503:CCEL RS05885
gene id: 394503:CCEL_RS05885
uniprot id: B8I031
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

394503:CCEL RS15110
gene id: 394503:CCEL_RS15110
uniprot id: B8I8W3
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

394503:CCEL RS04350
gene id: 394503:CCEL_RS04350
uniprot id: B8I8J6
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS06680
gene id: 394503:CCEL_RS06680
uniprot id: B8I186
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

394503:CCEL RS01900
gene id: 394503:CCEL_RS01900
uniprot id: B8I5V0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

394503:CCEL RS16235
gene id: 394503:CCEL_RS16235
uniprot id: B8I0X1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

394503:CCEL RS09605
gene id: 394503:CCEL_RS09605
uniprot id: B8I3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

394503:CCEL RS08205
gene id: 394503:CCEL_RS08205
uniprot id: B8I2I4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

394503:CCEL RS02265
gene id: 394503:CCEL_RS02265
uniprot id: B8I6D9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

394503:CCEL RS06445
gene id: 394503:CCEL_RS06445
uniprot id: B8I0R6
names: Similarity
messages: Belongs to the CobH/CbiC family.

394503:CCEL RS07865
gene id: 394503:CCEL_RS07865
uniprot id: B8I2B6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

394503:CCEL RS01425
gene id: 394503:CCEL_RS01425
uniprot id: B8I592
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

394503:CCEL RS06510
gene id: 394503:CCEL_RS06510
uniprot id: B8I0S8
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

394503:CCEL RS00100
gene id: 394503:CCEL_RS00100
uniprot id: B8I3S9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

394503:CCEL RS11550
gene id: 394503:CCEL_RS11550
uniprot id: B8I4W9
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

394503:CCEL RS00225
gene id: 394503:CCEL_RS00225
uniprot id: B8I3V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

394503:CCEL RS07070
gene id: 394503:CCEL_RS07070
uniprot id: B8I1G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS06360
gene id: 394503:CCEL_RS06360
uniprot id: B8I0P9
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS03645
gene id: 394503:CCEL_RS03645
uniprot id: B8I7T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

394503:CCEL RS12850
gene id: 394503:CCEL_RS12850
uniprot id: B8I6A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS04085
gene id: 394503:CCEL_RS04085
uniprot id: B8I824
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

394503:CCEL RS04050
gene id: 394503:CCEL_RS04050
uniprot id: B8I817
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

394503:CCEL RS09055
gene id: 394503:CCEL_RS09055
uniprot id: B8I2Z9
names: Similarity
messages: Belongs to the RemA family.

394503:CCEL RS17060
gene id: 394503:CCEL_RS17060
uniprot id: B8I1Q5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

394503:CCEL RS12170
gene id: 394503:CCEL_RS12170
uniprot id: B8I5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

394503:CCEL RS16670
gene id: 394503:CCEL_RS16670
uniprot id: B8I157
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

394503:CCEL RS09825
gene id: 394503:CCEL_RS09825
uniprot id: B8I3E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

394503:CCEL RS04405
gene id: 394503:CCEL_RS04405
uniprot id: B8I8K6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

394503:CCEL RS16065
gene id: 394503:CCEL_RS16065
uniprot id: B8I0G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

394503:CCEL RS08735
gene id: 394503:CCEL_RS08735
uniprot id: B8I2T9
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

394503:CCEL RS13090
gene id: 394503:CCEL_RS13090
uniprot id: B8I6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS03190
gene id: 394503:CCEL_RS03190
uniprot id: B8I785
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

394503:CCEL RS02110
gene id: 394503:CCEL_RS02110
uniprot id: B8I5Y6
names: Similarity
messages: Belongs to the MYG1 family.

394503:CCEL RS01355
gene id: 394503:CCEL_RS01355
uniprot id: B8I578
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

394503:CCEL RS11355
gene id: 394503:CCEL_RS11355
uniprot id: B8I4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

394503:CCEL RS02535
gene id: 394503:CCEL_RS02535
uniprot id: B8I6J4
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS03635
gene id: 394503:CCEL_RS03635
uniprot id: B8I7T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS10490
gene id: 394503:CCEL_RS10490
uniprot id: B8I3Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

394503:CCEL RS02395
gene id: 394503:CCEL_RS02395
uniprot id: B8I6G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

394503:CCEL RS08070
gene id: 394503:CCEL_RS08070
uniprot id: B8I2F7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

394503:CCEL RS12950
gene id: 394503:CCEL_RS12950
uniprot id: B8I6C3
names: Similarity
messages: Belongs to the transpeptidase family.

394503:CCEL RS03405
gene id: 394503:CCEL_RS03405
uniprot id: B8I7C5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

394503:CCEL RS01280
gene id: 394503:CCEL_RS01280
uniprot id: B8I563
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS17530
gene id: 394503:CCEL_RS17530
uniprot id: B8I2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

394503:CCEL RS10080
gene id: 394503:CCEL_RS10080
uniprot id: B8I3J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

394503:CCEL RS00420
gene id: 394503:CCEL_RS00420
uniprot id: B8I4B5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

394503:CCEL RS04410
gene id: 394503:CCEL_RS04410
uniprot id: B8I8K7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

394503:CCEL RS04740
gene id: 394503:CCEL_RS04740
uniprot id: B8I944
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the hyi family.
messages: Binds 1 Mn(2+) or Co(2+) ion per subunit. Can also use Mg(2+), Fe(2+) and Ni(2+) ions to a lesser extent.
messages: Homotetramer.
messages: Involved in the biosynthesis of D-psicose. Catalyzes the reversible epimerization of D-fructose at the C3 position to yield D-psicose. The enzyme is highly specific for D-psicose and shows very low activity with D-tagatose.

394503:CCEL RS06280
gene id: 394503:CCEL_RS06280
uniprot id: B8I0N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS01635
gene id: 394503:CCEL_RS01635
uniprot id: B8I5P7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

394503:CCEL RS00350
gene id: 394503:CCEL_RS00350
uniprot id: B8I4A1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

394503:CCEL RS10385
gene id: 394503:CCEL_RS10385
uniprot id: B8I3Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

394503:CCEL RS01860
gene id: 394503:CCEL_RS01860
uniprot id: B8I5U2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

394503:CCEL RS02280
gene id: 394503:CCEL_RS02280
uniprot id: B8I6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

394503:CCEL RS12750
gene id: 394503:CCEL_RS12750
uniprot id: B8I682
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

394503:CCEL RS04165
gene id: 394503:CCEL_RS04165
uniprot id: B8I8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

394503:CCEL RS01520
gene id: 394503:CCEL_RS01520
uniprot id: B8I5B1
names: Similarity
messages: Belongs to the DEAD box helicase family.

394503:CCEL RS11145
gene id: 394503:CCEL_RS11145
uniprot id: B8I4P2
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

394503:CCEL RS01290
gene id: 394503:CCEL_RS01290
uniprot id: B8I565
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

394503:CCEL RS01555
gene id: 394503:CCEL_RS01555
uniprot id: B8I5N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

394503:CCEL RS05290
gene id: 394503:CCEL_RS05290
uniprot id: B8I9F3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

394503:CCEL RS10510
gene id: 394503:CCEL_RS10510
uniprot id: B8I3Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

394503:CCEL RS11060
gene id: 394503:CCEL_RS11060
uniprot id: B8I4M6
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS08290
gene id: 394503:CCEL_RS08290
uniprot id: B8I2K1
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS10085
gene id: 394503:CCEL_RS10085
uniprot id: B8I3J7
names: Similarity
messages: Belongs to the ThiD family.

394503:CCEL RS12340
gene id: 394503:CCEL_RS12340
uniprot id: B8I600
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

394503:CCEL RS01075
gene id: 394503:CCEL_RS01075
uniprot id: B8I521
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

394503:CCEL RS02285
gene id: 394503:CCEL_RS02285
uniprot id: B8I6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

394503:CCEL RS00250
gene id: 394503:CCEL_RS00250
uniprot id: B8I3V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS00175
gene id: 394503:CCEL_RS00175
uniprot id: B8I3U4
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS09890
gene id: 394503:CCEL_RS09890
uniprot id: B8I3F8
names: Similarity
messages: Belongs to the RecJ family.

394503:CCEL RS11585
gene id: 394503:CCEL_RS11585
uniprot id: B8I4X6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

394503:CCEL RS00725
gene id: 394503:CCEL_RS00725
uniprot id: B8I4H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS01870
gene id: 394503:CCEL_RS01870
uniprot id: B8I5U4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

394503:CCEL RS00785
gene id: 394503:CCEL_RS00785
uniprot id: B8I4J0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

394503:CCEL RS10525
gene id: 394503:CCEL_RS10525
uniprot id: B8I3Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS00440
gene id: 394503:CCEL_RS00440
uniprot id: B8I4B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

394503:CCEL RS04755
gene id: 394503:CCEL_RS04755
uniprot id: B8I947
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS16180
gene id: 394503:CCEL_RS16180
uniprot id: B8I0W0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

394503:CCEL RS08065
gene id: 394503:CCEL_RS08065
uniprot id: B8I2F6
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

394503:CCEL RS08810
gene id: 394503:CCEL_RS08810
uniprot id: B8I2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

394503:CCEL RS05045
gene id: 394503:CCEL_RS05045
uniprot id: B8I9A6
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

394503:CCEL RS12960
gene id: 394503:CCEL_RS12960
uniprot id: B8I6P8
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

394503:CCEL RS10125
gene id: 394503:CCEL_RS10125
uniprot id: B8I3K7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

394503:CCEL RS03125
gene id: 394503:CCEL_RS03125
uniprot id: B8I772
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

394503:CCEL RS08865
gene id: 394503:CCEL_RS08865
uniprot id: B8I2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

394503:CCEL RS00065
gene id: 394503:CCEL_RS00065
uniprot id: B8I3S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

394503:CCEL RS00495
gene id: 394503:CCEL_RS00495
uniprot id: B8I4D0
names: Similarity
messages: Belongs to the bacterial flagellin family.

394503:CCEL RS09880
gene id: 394503:CCEL_RS09880
uniprot id: B8I3F6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

394503:CCEL RS03070
gene id: 394503:CCEL_RS03070
uniprot id: B8I761
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

394503:CCEL RS03980
gene id: 394503:CCEL_RS03980
uniprot id: B8I803
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

394503:CCEL RS03140
gene id: 394503:CCEL_RS03140
uniprot id: B8I775
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

394503:CCEL RS09090
gene id: 394503:CCEL_RS09090
uniprot id: B8I306
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

394503:CCEL RS03065
gene id: 394503:CCEL_RS03065
uniprot id: B8I760
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

394503:CCEL RS17250
gene id: 394503:CCEL_RS17250
uniprot id: B8I1T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

394503:CCEL RS10390
gene id: 394503:CCEL_RS10390
uniprot id: B8I3Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

394503:CCEL RS15555
gene id: 394503:CCEL_RS15555
uniprot id: B8I060
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

394503:CCEL RS02360
gene id: 394503:CCEL_RS02360
uniprot id: B8I6F8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

394503:CCEL RS17405
gene id: 394503:CCEL_RS17405
uniprot id: B8I292
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

394503:CCEL RS08525
gene id: 394503:CCEL_RS08525
uniprot id: B8I2P8
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS11245
gene id: 394503:CCEL_RS11245
uniprot id: B8I4R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS11035
gene id: 394503:CCEL_RS11035
uniprot id: B8I492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

394503:CCEL RS14470
gene id: 394503:CCEL_RS14470
uniprot id: B8I871
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

394503:CCEL RS09470
gene id: 394503:CCEL_RS09470
uniprot id: B8I375
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

394503:CCEL RS12345
gene id: 394503:CCEL_RS12345
uniprot id: B8I601
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

394503:CCEL RS06450
gene id: 394503:CCEL_RS06450
uniprot id: B8I0R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

394503:CCEL RS02365
gene id: 394503:CCEL_RS02365
uniprot id: B8I6F9
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS16215
gene id: 394503:CCEL_RS16215
uniprot id: B8I0W7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS07735
gene id: 394503:CCEL_RS07735
uniprot id: B8I259
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

394503:CCEL RS04710
gene id: 394503:CCEL_RS04710
uniprot id: B8I8R6
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

394503:CCEL RS07785
gene id: 394503:CCEL_RS07785
uniprot id: B8I268
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

394503:CCEL RS03375
gene id: 394503:CCEL_RS03375
uniprot id: B8I7B9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS06585
gene id: 394503:CCEL_RS06585
uniprot id: B8I168
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

394503:CCEL RS03865
gene id: 394503:CCEL_RS03865
uniprot id: B8I7Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

394503:CCEL RS15650
gene id: 394503:CCEL_RS15650
uniprot id: B8I081
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS16090
gene id: 394503:CCEL_RS16090
uniprot id: B8I0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

394503:CCEL RS04430
gene id: 394503:CCEL_RS04430
uniprot id: B8I8L1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

394503:CCEL RS00295
gene id: 394503:CCEL_RS00295
uniprot id: B8I3W7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

394503:CCEL RS03365
gene id: 394503:CCEL_RS03365
uniprot id: B8I7B7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

394503:CCEL RS00135
gene id: 394503:CCEL_RS00135
uniprot id: B8I3T6
names: Similarity
messages: Belongs to the PspA/IM30 family.

394503:CCEL RS11240
gene id: 394503:CCEL_RS11240
uniprot id: B8I4R1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

394503:CCEL RS04660
gene id: 394503:CCEL_RS04660
uniprot id: B8I8Q6
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

394503:CCEL RS06440
gene id: 394503:CCEL_RS06440
uniprot id: B8I0R5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

394503:CCEL RS15175
gene id: 394503:CCEL_RS15175
uniprot id: B8I8X5
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

394503:CCEL RS08660
gene id: 394503:CCEL_RS08660
uniprot id: B8I2S5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

394503:CCEL RS02330
gene id: 394503:CCEL_RS02330
uniprot id: B8I6F2
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Belongs to the carbamoyltransferase HypF family.

394503:CCEL RS03905
gene id: 394503:CCEL_RS03905
uniprot id: B8I7Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

394503:CCEL RS02310
gene id: 394503:CCEL_RS02310
uniprot id: B8I6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

394503:CCEL RS03605
gene id: 394503:CCEL_RS03605
uniprot id: B8I7T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

394503:CCEL RS06390
gene id: 394503:CCEL_RS06390
uniprot id: B8I0Q5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

394503:CCEL RS04065
gene id: 394503:CCEL_RS04065
uniprot id: B8I820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

394503:CCEL RS16720
gene id: 394503:CCEL_RS16720
uniprot id: B8I167
names: Similarity
messages: Belongs to the ABC transporter superfamily.

394503:CCEL RS09095
gene id: 394503:CCEL_RS09095
uniprot id: B8I307
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

394503:CCEL RS01945
gene id: 394503:CCEL_RS01945
uniprot id: B8I5V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

394503:CCEL RS14465
gene id: 394503:CCEL_RS14465
uniprot id: B8I870
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

394503:CCEL RS14675
gene id: 394503:CCEL_RS14675
uniprot id: B8I8A7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

394503:CCEL RS10235
gene id: 394503:CCEL_RS10235
uniprot id: B8I3M7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

394503:CCEL RS11385
gene id: 394503:CCEL_RS11385
uniprot id: B8I4U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

394503:CCEL RS05380
gene id: 394503:CCEL_RS05380
uniprot id: B8HZT1
names: Similarity
messages: Belongs to the peptidase A31 family.

394503:CCEL RS06765
gene id: 394503:CCEL_RS06765
uniprot id: B8I1A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

394503:CCEL RS02435
gene id: 394503:CCEL_RS02435
uniprot id: B8I6H4
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

394503:CCEL RS17200
gene id: 394503:CCEL_RS17200
uniprot id: B8I1S9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

394503:CCEL RS14710
gene id: 394503:CCEL_RS14710
uniprot id: B8I8B4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS10485
gene id: 394503:CCEL_RS10485
uniprot id: B8I3Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

394503:CCEL RS03430
gene id: 394503:CCEL_RS03430
uniprot id: B8I7D0
names: Similarity
messages: Belongs to the CinA family.

394503:CCEL RS01980
gene id: 394503:CCEL_RS01980
uniprot id: B8I5W6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

394503:CCEL RS05160
gene id: 394503:CCEL_RS05160
uniprot id: B8I9C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS16970
gene id: 394503:CCEL_RS16970
uniprot id: B8I1N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

394503:CCEL RS11810
gene id: 394503:CCEL_RS11810
uniprot id: B8I5D7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

394503:CCEL RS11235
gene id: 394503:CCEL_RS11235
uniprot id: B8I4R0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

394503:CCEL RS07085
gene id: 394503:CCEL_RS07085
uniprot id: B8I1G4
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS09945
gene id: 394503:CCEL_RS09945
uniprot id: B8I3G9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

394503:CCEL RS11590
gene id: 394503:CCEL_RS11590
uniprot id: B8I4X7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

394503:CCEL RS12820
gene id: 394503:CCEL_RS12820
uniprot id: B8I696
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

394503:CCEL RS07170
gene id: 394503:CCEL_RS07170
uniprot id: B8I1I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

394503:CCEL RS04105
gene id: 394503:CCEL_RS04105
uniprot id: B8I8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

394503:CCEL RS10630
gene id: 394503:CCEL_RS10630
uniprot id: B8I413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

394503:CCEL RS13125
gene id: 394503:CCEL_RS13125
uniprot id: B8I6T1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

394503:CCEL RS12710
gene id: 394503:CCEL_RS12710
uniprot id: B8I674
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

394503:CCEL RS03495
gene id: 394503:CCEL_RS03495
uniprot id: B8I7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

394503:CCEL RS10315
gene id: 394503:CCEL_RS10315
uniprot id: B8I3P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

394503:CCEL RS01730
gene id: 394503:CCEL_RS01730
uniprot id: B8I5R6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

394503:CCEL RS01450
gene id: 394503:CCEL_RS01450
uniprot id: B8I597
names: Similarity
messages: Belongs to the peptidase S41A family.

394503:CCEL RS09780
gene id: 394503:CCEL_RS09780
uniprot id: B8I3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

394503:CCEL RS03450
gene id: 394503:CCEL_RS03450
uniprot id: B8I7D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

394503:CCEL RS00040
gene id: 394503:CCEL_RS00040
uniprot id: B8I3R9
names: Similarity
messages: Belongs to the ParB family.

394503:CCEL RS04765
gene id: 394503:CCEL_RS04765
uniprot id: B8I949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS12655
gene id: 394503:CCEL_RS12655
uniprot id: B8I663
names: Similarity
messages: Belongs to the Tlp family.

394503:CCEL RS14420
gene id: 394503:CCEL_RS14420
uniprot id: B8I861
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

394503:CCEL RS04560
gene id: 394503:CCEL_RS04560
uniprot id: B8I8N7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

394503:CCEL RS07705
gene id: 394503:CCEL_RS07705
uniprot id: B8I253
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

394503:CCEL RS00905
gene id: 394503:CCEL_RS00905
uniprot id: B8I4L4
names: Similarity
messages: Belongs to the IMPACT family.

394503:CCEL RS09660
gene id: 394503:CCEL_RS09660
uniprot id: B8I3B3
names: Similarity
messages: Belongs to the asp23 family.

394503:CCEL RS03280
gene id: 394503:CCEL_RS03280
uniprot id: B8I7A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

394503:CCEL RS04170
gene id: 394503:CCEL_RS04170
uniprot id: B8I8G5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

394503:CCEL RS12555
gene id: 394503:CCEL_RS12555
uniprot id: B8I643
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS16040
gene id: 394503:CCEL_RS16040
uniprot id: B8I0G2
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

394503:CCEL RS12585
gene id: 394503:CCEL_RS12585
uniprot id: B8I649
names: Cofactor
messages: Binds 1 zinc ion per subunit.

394503:CCEL RS13240
gene id: 394503:CCEL_RS13240
uniprot id: B8I6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

394503:CCEL RS00525
gene id: 394503:CCEL_RS00525
uniprot id: B8I4D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

394503:CCEL RS11180
gene id: 394503:CCEL_RS11180
uniprot id: B8I4P9
names: Similarity
messages: Belongs to the thioredoxin family.

394503:CCEL RS03855
gene id: 394503:CCEL_RS03855
uniprot id: B8I7X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

394503:CCEL RS10300
gene id: 394503:CCEL_RS10300
uniprot id: B8I3P0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS00695
gene id: 394503:CCEL_RS00695
uniprot id: B8I4H2
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

394503:CCEL RS10145
gene id: 394503:CCEL_RS10145
uniprot id: B8I3L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

394503:CCEL RS08480
gene id: 394503:CCEL_RS08480
uniprot id: B8I2N9
names: Similarity
messages: Belongs to the HypE family.

394503:CCEL RS09065
gene id: 394503:CCEL_RS09065
uniprot id: B8I301
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS07685
gene id: 394503:CCEL_RS07685
uniprot id: B8I249
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

394503:CCEL RS10445
gene id: 394503:CCEL_RS10445
uniprot id: B8I3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

394503:CCEL RS04235
gene id: 394503:CCEL_RS04235
uniprot id: B8I8H8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

394503:CCEL RS17545
gene id: 394503:CCEL_RS17545
uniprot id: B8I2B5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

394503:CCEL RS03930
gene id: 394503:CCEL_RS03930
uniprot id: B8I7Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

394503:CCEL RS01865
gene id: 394503:CCEL_RS01865
uniprot id: B8I5U3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

394503:CCEL RS17425
gene id: 394503:CCEL_RS17425
uniprot id: B8I297
names: Similarity
messages: Belongs to the UPF0047 family.

394503:CCEL RS16675
gene id: 394503:CCEL_RS16675
uniprot id: B8I158
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

394503:CCEL RS02750
gene id: 394503:CCEL_RS02750
uniprot id: B8I6N4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

394503:CCEL RS09480
gene id: 394503:CCEL_RS09480
uniprot id: B8I377
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

394503:CCEL RS07275
gene id: 394503:CCEL_RS07275
uniprot id: B8I1X1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

394503:CCEL RS02195
gene id: 394503:CCEL_RS02195
uniprot id: B8I6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS03925
gene id: 394503:CCEL_RS03925
uniprot id: B8I7Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

394503:CCEL RS08705
gene id: 394503:CCEL_RS08705
uniprot id: B8I2T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

394503:CCEL RS03515
gene id: 394503:CCEL_RS03515
uniprot id: B8I7R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

394503:CCEL RS11465
gene id: 394503:CCEL_RS11465
uniprot id: B8I4V3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS04345
gene id: 394503:CCEL_RS04345
uniprot id: B8I8J5
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS09730
gene id: 394503:CCEL_RS09730
uniprot id: B8I3C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

394503:CCEL RS09815
gene id: 394503:CCEL_RS09815
uniprot id: B8I3E4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

394503:CCEL RS00510
gene id: 394503:CCEL_RS00510
uniprot id: B8I4D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

394503:CCEL RS00415
gene id: 394503:CCEL_RS00415
uniprot id: B8I4B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

394503:CCEL RS07480
gene id: 394503:CCEL_RS07480
uniprot id: B8I210
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

394503:CCEL RS08835
gene id: 394503:CCEL_RS08835
uniprot id: B8I2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

394503:CCEL RS11605
gene id: 394503:CCEL_RS11605
uniprot id: B8I4X8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

394503:CCEL RS09020
gene id: 394503:CCEL_RS09020
uniprot id: B8I2Z2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

394503:CCEL RS13200
gene id: 394503:CCEL_RS13200
uniprot id: B8I6U7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

394503:CCEL RS07700
gene id: 394503:CCEL_RS07700
uniprot id: B8I252
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

394503:CCEL RS05475
gene id: 394503:CCEL_RS05475
uniprot id: B8HZV1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

394503:CCEL RS17025
gene id: 394503:CCEL_RS17025
uniprot id: B8I1P8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

394503:CCEL RS08490
gene id: 394503:CCEL_RS08490
uniprot id: B8I2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

394503:CCEL RS17030
gene id: 394503:CCEL_RS17030
uniprot id: B8I1P9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

394503:CCEL RS13060
gene id: 394503:CCEL_RS13060
uniprot id: B8I6R8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS00810
gene id: 394503:CCEL_RS00810
uniprot id: B8I4J5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

394503:CCEL RS08725
gene id: 394503:CCEL_RS08725
uniprot id: B8I2T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

394503:CCEL RS12270
gene id: 394503:CCEL_RS12270
uniprot id: B8I5L5
names: Similarity
messages: Belongs to the class-I fumarase family.

394503:CCEL RS09535
gene id: 394503:CCEL_RS09535
uniprot id: B8I388
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

394503:CCEL RS01360
gene id: 394503:CCEL_RS01360
uniprot id: B8I579
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

394503:CCEL RS16995
gene id: 394503:CCEL_RS16995
uniprot id: B8I1P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS11715
gene id: 394503:CCEL_RS11715
uniprot id: B8I5B8
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS14820
gene id: 394503:CCEL_RS14820
uniprot id: B8I8D6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

394503:CCEL RS02245
gene id: 394503:CCEL_RS02245
uniprot id: B8I6D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

394503:CCEL RS11370
gene id: 394503:CCEL_RS11370
uniprot id: B8I4T7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS00720
gene id: 394503:CCEL_RS00720
uniprot id: B8I4H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS06995
gene id: 394503:CCEL_RS06995
uniprot id: B8I1E7
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

394503:CCEL RS01630
gene id: 394503:CCEL_RS01630
uniprot id: B8I5P6
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

394503:CCEL RS03815
gene id: 394503:CCEL_RS03815
uniprot id: Q0PRM9
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

394503:CCEL RS06010
gene id: 394503:CCEL_RS06010
uniprot id: B8I0I1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

394503:CCEL RS12900
gene id: 394503:CCEL_RS12900
uniprot id: B8I6B2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

394503:CCEL RS09405
gene id: 394503:CCEL_RS09405
uniprot id: B8I364
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

394503:CCEL RS12995
gene id: 394503:CCEL_RS12995
uniprot id: B8I6Q5
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

394503:CCEL RS01545
gene id: 394503:CCEL_RS01545
uniprot id: B8I5M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

394503:CCEL RS03110
gene id: 394503:CCEL_RS03110
uniprot id: B8I769
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

394503:CCEL RS06285
gene id: 394503:CCEL_RS06285
uniprot id: B8I0N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS06210
gene id: 394503:CCEL_RS06210
uniprot id: B8I0M0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

394503:CCEL RS00685
gene id: 394503:CCEL_RS00685
uniprot id: B8I4H0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS01365
gene id: 394503:CCEL_RS01365
uniprot id: B8I580
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

394503:CCEL RS09975
gene id: 394503:CCEL_RS09975
uniprot id: B8I3H6
names: Similarity
messages: Belongs to the GerABKA family.

394503:CCEL RS16715
gene id: 394503:CCEL_RS16715
uniprot id: B8I166
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS14810
gene id: 394503:CCEL_RS14810
uniprot id: B8I8D4
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS02270
gene id: 394503:CCEL_RS02270
uniprot id: B8I6E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

394503:CCEL RS17430
gene id: 394503:CCEL_RS17430
uniprot id: B8I298
names: Similarity
messages: Belongs to the SfsA family.

394503:CCEL RS06685
gene id: 394503:CCEL_RS06685
uniprot id: B8I187
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

394503:CCEL RS07165
gene id: 394503:CCEL_RS07165
uniprot id: B8I1I0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

394503:CCEL RS02320
gene id: 394503:CCEL_RS02320
uniprot id: B8I6F0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

394503:CCEL RS05195
gene id: 394503:CCEL_RS05195
uniprot id: B8I9D6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

394503:CCEL RS09180
gene id: 394503:CCEL_RS09180
uniprot id: B8I324
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS05660
gene id: 394503:CCEL_RS05660
uniprot id: B8HZY7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS08690
gene id: 394503:CCEL_RS08690
uniprot id: B8I2T1
names: Similarity
messages: Belongs to the UPF0237 family.

394503:CCEL RS13205
gene id: 394503:CCEL_RS13205
uniprot id: B8I6U8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS04720
gene id: 394503:CCEL_RS04720
uniprot id: B8I941
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

394503:CCEL RS16835
gene id: 394503:CCEL_RS16835
uniprot id: B8I1L1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

394503:CCEL RS00635
gene id: 394503:CCEL_RS00635
uniprot id: B8I4G0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

394503:CCEL RS09905
gene id: 394503:CCEL_RS09905
uniprot id: B8I3G1
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS09410
gene id: 394503:CCEL_RS09410
uniprot id: B8I365
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS11065
gene id: 394503:CCEL_RS11065
uniprot id: B8I4M7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

394503:CCEL RS10950
gene id: 394503:CCEL_RS10950
uniprot id: B8I477
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

394503:CCEL RS07375
gene id: 394503:CCEL_RS07375
uniprot id: B8I1Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

394503:CCEL RS17240
gene id: 394503:CCEL_RS17240
uniprot id: B8I1T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

394503:CCEL RS13115
gene id: 394503:CCEL_RS13115
uniprot id: B8I6S9
names: Similarity
messages: Belongs to the RutC family.

394503:CCEL RS02105
gene id: 394503:CCEL_RS02105
uniprot id: B8I268
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

394503:CCEL RS05220
gene id: 394503:CCEL_RS05220
uniprot id: B8I9E1
names: Similarity
messages: Belongs to the group II decarboxylase family.

394503:CCEL RS04715
gene id: 394503:CCEL_RS04715
uniprot id: B8I940
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

394503:CCEL RS09445
gene id: 394503:CCEL_RS09445
uniprot id: B8I371
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

394503:CCEL RS10020
gene id: 394503:CCEL_RS10020
uniprot id: B8I3I4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

394503:CCEL RS05860
gene id: 394503:CCEL_RS05860
uniprot id: B8I026
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS11305
gene id: 394503:CCEL_RS11305
uniprot id: B8I4S4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

394503:CCEL RS01035
gene id: 394503:CCEL_RS01035
uniprot id: B8I512
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.

394503:CCEL RS16290
gene id: 394503:CCEL_RS16290
uniprot id: B8I0Y2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS10420
gene id: 394503:CCEL_RS10420
uniprot id: B8I3X4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

394503:CCEL RS11390
gene id: 394503:CCEL_RS11390
uniprot id: B8I4U1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

394503:CCEL RS17215
gene id: 394503:CCEL_RS17215
uniprot id: B8I1T2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

394503:CCEL RS09530
gene id: 394503:CCEL_RS09530
uniprot id: B8I387
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

394503:CCEL RS11030
gene id: 394503:CCEL_RS11030
uniprot id: B8I491
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS03540
gene id: 394503:CCEL_RS03540
uniprot id: B8I7R8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

394503:CCEL RS08615
gene id: 394503:CCEL_RS08615
uniprot id: B8I2R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

394503:CCEL RS07750
gene id: 394503:CCEL_RS07750
uniprot id: B8I262
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

394503:CCEL RS06460
gene id: 394503:CCEL_RS06460
uniprot id: B8I0R9
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

394503:CCEL RS04455
gene id: 394503:CCEL_RS04455
uniprot id: B8I8L6
names: Subcellular Location Annotation
messages: Cell membrane

394503:CCEL RS05060
gene id: 394503:CCEL_RS05060
uniprot id: B8I9A9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

394503:CCEL RS06795
gene id: 394503:CCEL_RS06795
uniprot id: B8I1A9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

394503:CCEL RS08975
gene id: 394503:CCEL_RS08975
uniprot id: B8I2Y3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

394503:CCEL RS10790
gene id: 394503:CCEL_RS10790
uniprot id: B8I445
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

394503:CCEL RS03955
gene id: 394503:CCEL_RS03955
uniprot id: B8I7Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

394503:CCEL RS09610
gene id: 394503:CCEL_RS09610
uniprot id: B8I3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

394503:CCEL RS14685
gene id: 394503:CCEL_RS14685
uniprot id: B8I8A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

394503:CCEL RS01575
gene id: 394503:CCEL_RS01575
uniprot id: B8I5N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

394503:CCEL RS04700
gene id: 394503:CCEL_RS04700
uniprot id: Q0PRN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

394503:CCEL RS15005
gene id: 394503:CCEL_RS15005
uniprot id: B8I8U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

394503:CCEL RS10005
gene id: 394503:CCEL_RS10005
uniprot id: B8I3I1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

394503:CCEL RS09400
gene id: 394503:CCEL_RS09400
uniprot id: B8I363
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

394503:CCEL RS04360
gene id: 394503:CCEL_RS04360
uniprot id: B8I8J8
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

394503:CCEL RS12440
gene id: 394503:CCEL_RS12440
uniprot id: B8I620
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS01345
gene id: 394503:CCEL_RS01345
uniprot id: B8I576
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

394503:CCEL RS10290
gene id: 394503:CCEL_RS10290
uniprot id: B8I3N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

394503:CCEL RS14425
gene id: 394503:CCEL_RS14425
uniprot id: B8I862
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

394503:CCEL RS04040
gene id: 394503:CCEL_RS04040
uniprot id: B8I815
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

394503:CCEL RS06195
gene id: 394503:CCEL_RS06195
uniprot id: Q0PRN3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

394503:CCEL RS10435
gene id: 394503:CCEL_RS10435
uniprot id: B8I3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

394503:CCEL RS09040
gene id: 394503:CCEL_RS09040
uniprot id: B8I2Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS06890
gene id: 394503:CCEL_RS06890
uniprot id: B8I1C6
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

394503:CCEL RS03675
gene id: 394503:CCEL_RS03675
uniprot id: B8I7U5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

394503:CCEL RS02335
gene id: 394503:CCEL_RS02335
uniprot id: B8I6F3
names: Similarity
messages: Belongs to the HupF/HypC family.

394503:CCEL RS02585
gene id: 394503:CCEL_RS02585
uniprot id: B8I6K5
names: Similarity
messages: Belongs to the UPF0047 family.

394503:CCEL RS09085
gene id: 394503:CCEL_RS09085
uniprot id: B8I305
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

394503:CCEL RS02620
gene id: 394503:CCEL_RS02620
uniprot id: B8I6L2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

394503:CCEL RS03810
gene id: 394503:CCEL_RS03810
uniprot id: Q0PRN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

394503:CCEL RS13370
gene id: 394503:CCEL_RS13370
uniprot id: B8I6X8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS03590
gene id: 394503:CCEL_RS03590
uniprot id: B8I7S8
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS08110
gene id: 394503:CCEL_RS08110
uniprot id: B8I2G5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

394503:CCEL RS09165
gene id: 394503:CCEL_RS09165
uniprot id: B8I321
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

394503:CCEL RS01950
gene id: 394503:CCEL_RS01950
uniprot id: B8I5W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

394503:CCEL RS14300
gene id: 394503:CCEL_RS14300
uniprot id: B8I836
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

394503:CCEL RS01620
gene id: 394503:CCEL_RS01620
uniprot id: B8I5P4
names: Similarity
messages: Belongs to the CtsR family.

394503:CCEL RS02420
gene id: 394503:CCEL_RS02420
uniprot id: B8I6H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

394503:CCEL RS05090
gene id: 394503:CCEL_RS05090
uniprot id: B8I9B5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

394503:CCEL RS10335
gene id: 394503:CCEL_RS10335
uniprot id: B8I3P7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

394503:CCEL RS10140
gene id: 394503:CCEL_RS10140
uniprot id: B8I3L0
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

394503:CCEL RS10560
gene id: 394503:CCEL_RS10560
uniprot id: B8I3Z9
names: Subcellular Location Annotation
messages: Cell membrane

394503:CCEL RS07360
gene id: 394503:CCEL_RS07360
uniprot id: B8I1Y8
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

394503:CCEL RS05505
gene id: 394503:CCEL_RS05505
uniprot id: B8HZV7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS13055
gene id: 394503:CCEL_RS13055
uniprot id: B8I6R7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

394503:CCEL RS03475
gene id: 394503:CCEL_RS03475
uniprot id: B8I7Q6
names: Similarity
messages: Belongs to the fabD family.

394503:CCEL RS07425
gene id: 394503:CCEL_RS07425
uniprot id: B8I201
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

394503:CCEL RS01565
gene id: 394503:CCEL_RS01565
uniprot id: B8I5N3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

394503:CCEL RS05755
gene id: 394503:CCEL_RS05755
uniprot id: B8I005
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

394503:CCEL RS08610
gene id: 394503:CCEL_RS08610
uniprot id: B8I2R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

394503:CCEL RS09935
gene id: 394503:CCEL_RS09935
uniprot id: B8I3G7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

394503:CCEL RS12190
gene id: 394503:CCEL_RS12190
uniprot id: B8I5K8
names: Similarity
messages: Belongs to the GSP E family.

394503:CCEL RS07315
gene id: 394503:CCEL_RS07315
uniprot id: B8I1X9
names: Similarity
messages: Belongs to the UPF0735 family.

394503:CCEL RS03725
gene id: 394503:CCEL_RS03725
uniprot id: B8I7V6
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

394503:CCEL RS15665
gene id: 394503:CCEL_RS15665
uniprot id: B8I084
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

394503:CCEL RS06110
gene id: 394503:CCEL_RS06110
uniprot id: B8I0K0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

394503:CCEL RS03800
gene id: 394503:CCEL_RS03800
uniprot id: B8I7X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 11 (cellulase G) family.

394503:CCEL RS01845
gene id: 394503:CCEL_RS01845
uniprot id: B8I5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS07270
gene id: 394503:CCEL_RS07270
uniprot id: B8I1X0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

394503:CCEL RS03100
gene id: 394503:CCEL_RS03100
uniprot id: B8I767
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

394503:CCEL RS10075
gene id: 394503:CCEL_RS10075
uniprot id: B8I3J5
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

394503:CCEL RS02495
gene id: 394503:CCEL_RS02495
uniprot id: B8I6I6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

394503:CCEL RS00425
gene id: 394503:CCEL_RS00425
uniprot id: B8I4B6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

394503:CCEL RS06225
gene id: 394503:CCEL_RS06225
uniprot id: B8I0M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

394503:CCEL RS14480
gene id: 394503:CCEL_RS14480
uniprot id: B8I873
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

394503:CCEL RS10310
gene id: 394503:CCEL_RS10310
uniprot id: B8I3P2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

394503:CCEL RS16115
gene id: 394503:CCEL_RS16115
uniprot id: B8I0U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

394503:CCEL RS07115
gene id: 394503:CCEL_RS07115
uniprot id: B8I1H1
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS05000
gene id: 394503:CCEL_RS05000
uniprot id: B8I997
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS06145
gene id: 394503:CCEL_RS06145
uniprot id: B8I0K7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS09045
gene id: 394503:CCEL_RS09045
uniprot id: B8I2Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

394503:CCEL RS01970
gene id: 394503:CCEL_RS01970
uniprot id: B8I5W4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS15560
gene id: 394503:CCEL_RS15560
uniprot id: B8I061
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

394503:CCEL RS11070
gene id: 394503:CCEL_RS11070
uniprot id: B8I4M8
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

394503:CCEL RS00690
gene id: 394503:CCEL_RS00690
uniprot id: B8I4H1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS03630
gene id: 394503:CCEL_RS03630
uniprot id: B8I7T6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

394503:CCEL RS05080
gene id: 394503:CCEL_RS05080
uniprot id: B8I9B3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS08115
gene id: 394503:CCEL_RS08115
uniprot id: B8I2G6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

394503:CCEL RS15880
gene id: 394503:CCEL_RS15880
uniprot id: B8I0C8
names: Similarity
messages: Belongs to the ParB family.

394503:CCEL RS05155
gene id: 394503:CCEL_RS05155
uniprot id: B8I9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS04120
gene id: 394503:CCEL_RS04120
uniprot id: B8I8F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

394503:CCEL RS00020
gene id: 394503:CCEL_RS00020
uniprot id: B8I3R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

394503:CCEL RS16735
gene id: 394503:CCEL_RS16735
uniprot id: B8I1J1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

394503:CCEL RS02090
gene id: 394503:CCEL_RS02090
uniprot id: B8I5Y2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

394503:CCEL RS09740
gene id: 394503:CCEL_RS09740
uniprot id: B8I3C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

394503:CCEL RS11415
gene id: 394503:CCEL_RS11415
uniprot id: B8I4U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

394503:CCEL RS03315
gene id: 394503:CCEL_RS03315
uniprot id: B8I7A9
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

394503:CCEL RS07345
gene id: 394503:CCEL_RS07345
uniprot id: B8I1Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

394503:CCEL RS10550
gene id: 394503:CCEL_RS10550
uniprot id: B8I3Z8
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS11135
gene id: 394503:CCEL_RS11135
uniprot id: B8I4P0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

394503:CCEL RS04495
gene id: 394503:CCEL_RS04495
uniprot id: B8I8M4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

394503:CCEL RS13135
gene id: 394503:CCEL_RS13135
uniprot id: B8I6T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

394503:CCEL RS08275
gene id: 394503:CCEL_RS08275
uniprot id: B8I2J8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

394503:CCEL RS03000
gene id: 394503:CCEL_RS03000
uniprot id: B8I747
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

394503:CCEL RS09630
gene id: 394503:CCEL_RS09630
uniprot id: B8I3A7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

394503:CCEL RS07755
gene id: 394503:CCEL_RS07755
uniprot id: B8I263
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

394503:CCEL RS04005
gene id: 394503:CCEL_RS04005
uniprot id: B8I808
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

394503:CCEL RS05430
gene id: 394503:CCEL_RS05430
uniprot id: B8HZU1
names: Similarity
messages: Belongs to the BtpA family.

394503:CCEL RS11020
gene id: 394503:CCEL_RS11020
uniprot id: B8I489
names: Similarity
messages: Belongs to the GARS family.

394503:CCEL RS07355
gene id: 394503:CCEL_RS07355
uniprot id: B8I1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

394503:CCEL RS12515
gene id: 394503:CCEL_RS12515
uniprot id: B8I634
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

394503:CCEL RS00255
gene id: 394503:CCEL_RS00255
uniprot id: B8I3W0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

394503:CCEL RS07180
gene id: 394503:CCEL_RS07180
uniprot id: B8I1I3
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS06770
gene id: 394503:CCEL_RS06770
uniprot id: B8I1A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

394503:CCEL RS08830
gene id: 394503:CCEL_RS08830
uniprot id: B8I2V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

394503:CCEL RS00005
gene id: 394503:CCEL_RS00005
uniprot id: B8I3R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

394503:CCEL RS00775
gene id: 394503:CCEL_RS00775
uniprot id: B8I4I8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

394503:CCEL RS00180
gene id: 394503:CCEL_RS00180
uniprot id: B8I3U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

394503:CCEL RS05870
gene id: 394503:CCEL_RS05870
uniprot id: B8I028
names: Similarity
messages: Belongs to the EamA transporter family.

394503:CCEL RS12125
gene id: 394503:CCEL_RS12125
uniprot id: B8I5J5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

394503:CCEL RS03120
gene id: 394503:CCEL_RS03120
uniprot id: B8I771
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

394503:CCEL RS10800
gene id: 394503:CCEL_RS10800
uniprot id: B8I447
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

394503:CCEL RS02605
gene id: 394503:CCEL_RS02605
uniprot id: B8I6K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

394503:CCEL RS12335
gene id: 394503:CCEL_RS12335
uniprot id: B8I5M8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

394503:CCEL RS00010
gene id: 394503:CCEL_RS00010
uniprot id: B8I3R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

394503:CCEL RS12650
gene id: 394503:CCEL_RS12650
uniprot id: B8I661
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS01275
gene id: 394503:CCEL_RS01275
uniprot id: B8I562
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

394503:CCEL RS01915
gene id: 394503:CCEL_RS01915
uniprot id: B8I5V3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

394503:CCEL RS00230
gene id: 394503:CCEL_RS00230
uniprot id: B8I3V5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

394503:CCEL RS06415
gene id: 394503:CCEL_RS06415
uniprot id: B8I0R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

394503:CCEL RS10805
gene id: 394503:CCEL_RS10805
uniprot id: B8I448
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

394503:CCEL RS13910
gene id: 394503:CCEL_RS13910
uniprot id: B8I7I9
names: Similarity
messages: Belongs to the pirin family.

394503:CCEL RS03785
gene id: 394503:CCEL_RS03785
uniprot id: B8I7W8
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS06640
gene id: 394503:CCEL_RS06640
uniprot id: B8I178
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

394503:CCEL RS06670
gene id: 394503:CCEL_RS06670
uniprot id: B8I184
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homomer.

394503:CCEL RS02275
gene id: 394503:CCEL_RS02275
uniprot id: B8I6E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

394503:CCEL RS12565
gene id: 394503:CCEL_RS12565
uniprot id: B8I645
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS01510
gene id: 394503:CCEL_RS01510
uniprot id: B8I5A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

394503:CCEL RS08440
gene id: 394503:CCEL_RS08440
uniprot id: B8I2N1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

394503:CCEL RS00765
gene id: 394503:CCEL_RS00765
uniprot id: B8I4I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS04265
gene id: 394503:CCEL_RS04265
uniprot id: P25472
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.

394503:CCEL RS04045
gene id: 394503:CCEL_RS04045
uniprot id: B8I816
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

394503:CCEL RS03890
gene id: 394503:CCEL_RS03890
uniprot id: B8I7Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

394503:CCEL RS05405
gene id: 394503:CCEL_RS05405
uniprot id: B8HZT6
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS03660
gene id: 394503:CCEL_RS03660
uniprot id: B8I7U2
names: Similarity
messages: Belongs to the UPF0102 family.

394503:CCEL RS12300
gene id: 394503:CCEL_RS12300
uniprot id: B8I5M1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

394503:CCEL RS01810
gene id: 394503:CCEL_RS01810
uniprot id: B8I5T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

394503:CCEL RS00160
gene id: 394503:CCEL_RS00160
uniprot id: B8I3U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

394503:CCEL RS11315
gene id: 394503:CCEL_RS11315
uniprot id: B8I4S6
names: Similarity
messages: Belongs to the UPF0473 family.

394503:CCEL RS10900
gene id: 394503:CCEL_RS10900
uniprot id: B8I466
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS03965
gene id: 394503:CCEL_RS03965
uniprot id: B8I800
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

394503:CCEL RS10355
gene id: 394503:CCEL_RS10355
uniprot id: B8I3Q1
names: Subcellular Location Annotation
messages: Cytoplasm

394503:CCEL RS03510
gene id: 394503:CCEL_RS03510
uniprot id: B8I7R3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

394503:CCEL RS12975
gene id: 394503:CCEL_RS12975
uniprot id: B8I6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

394503:CCEL RS13770
gene id: 394503:CCEL_RS13770
uniprot id: B8I7G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

394503:CCEL RS12180
gene id: 394503:CCEL_RS12180
uniprot id: B8I5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS03990
gene id: 394503:CCEL_RS03990
uniprot id: B8I805
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

394503:CCEL RS01825
gene id: 394503:CCEL_RS01825
uniprot id: B8I5T5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

394503:CCEL RS08920
gene id: 394503:CCEL_RS08920
uniprot id: B8I2X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS01505
gene id: 394503:CCEL_RS01505
uniprot id: B8I5A8
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS14670
gene id: 394503:CCEL_RS14670
uniprot id: B8I8A6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

394503:CCEL RS08230
gene id: 394503:CCEL_RS08230
uniprot id: B8I2I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS01735
gene id: 394503:CCEL_RS01735
uniprot id: B8I5R7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

394503:CCEL RS12430
gene id: 394503:CCEL_RS12430
uniprot id: B8I618
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

394503:CCEL RS16985
gene id: 394503:CCEL_RS16985
uniprot id: B8I1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

394503:CCEL RS02475
gene id: 394503:CCEL_RS02475
uniprot id: B8I6I2
names: Similarity
messages: Belongs to the heat shock protein 90 family.

394503:CCEL RS09485
gene id: 394503:CCEL_RS09485
uniprot id: B8I378
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

394503:CCEL RS01220
gene id: 394503:CCEL_RS01220
uniprot id: B8I550
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

394503:CCEL RS14740
gene id: 394503:CCEL_RS14740
uniprot id: B8I8C0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

394503:CCEL RS07445
gene id: 394503:CCEL_RS07445
uniprot id: B8I205
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

394503:CCEL RS00490
gene id: 394503:CCEL_RS00490
uniprot id: B8I4C9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

394503:CCEL RS01680
gene id: 394503:CCEL_RS01680
uniprot id: B8I5Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

394503:CCEL RS07420
gene id: 394503:CCEL_RS07420
uniprot id: B8I200
names: Caution
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS03600
gene id: 394503:CCEL_RS03600
uniprot id: B8I7T0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

394503:CCEL RS04125
gene id: 394503:CCEL_RS04125
uniprot id: B8I8F6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

394503:CCEL RS06190
gene id: 394503:CCEL_RS06190
uniprot id: B8I0L6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS06270
gene id: 394503:CCEL_RS06270
uniprot id: B8I0N2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS09030
gene id: 394503:CCEL_RS09030
uniprot id: B8I2Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

394503:CCEL RS12575
gene id: 394503:CCEL_RS12575
uniprot id: B8I647
names: Similarity
messages: Belongs to the hemerythrin family.

394503:CCEL RS01855
gene id: 394503:CCEL_RS01855
uniprot id: B8I5U1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

394503:CCEL RS05835
gene id: 394503:CCEL_RS05835
uniprot id: B8I021
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

394503:CCEL RS11310
gene id: 394503:CCEL_RS11310
uniprot id: B8I4S5
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS02240
gene id: 394503:CCEL_RS02240
uniprot id: B8I6D4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS11045
gene id: 394503:CCEL_RS11045
uniprot id: B8I494
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

394503:CCEL RS08140
gene id: 394503:CCEL_RS08140
uniprot id: B8I2H1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

394503:CCEL RS14490
gene id: 394503:CCEL_RS14490
uniprot id: B8I875
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

394503:CCEL RS16135
gene id: 394503:CCEL_RS16135
uniprot id: B8I0V1
names: Similarity
messages: Belongs to the TrpF family.

394503:CCEL RS02430
gene id: 394503:CCEL_RS02430
uniprot id: B8I6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

394503:CCEL RS08890
gene id: 394503:CCEL_RS08890
uniprot id: B8I2X0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

394503:CCEL RS09555
gene id: 394503:CCEL_RS09555
uniprot id: B8I392
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

394503:CCEL RS10595
gene id: 394503:CCEL_RS10595
uniprot id: B8I406
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

394503:CCEL RS10690
gene id: 394503:CCEL_RS10690
uniprot id: B8I425
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS03490
gene id: 394503:CCEL_RS03490
uniprot id: B8I7Q9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

394503:CCEL RS08130
gene id: 394503:CCEL_RS08130
uniprot id: B8I2G9
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

394503:CCEL RS03160
gene id: 394503:CCEL_RS03160
uniprot id: B8I779
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

394503:CCEL RS10070
gene id: 394503:CCEL_RS10070
uniprot id: B8I3J4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

394503:CCEL RS02610
gene id: 394503:CCEL_RS02610
uniprot id: B8I6L0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

394503:CCEL RS04055
gene id: 394503:CCEL_RS04055
uniprot id: B8I818
names: Similarity
messages: Belongs to the DtxR/MntR family.

394503:CCEL RS12955
gene id: 394503:CCEL_RS12955
uniprot id: B8I6C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

394503:CCEL RS16905
gene id: 394503:CCEL_RS16905
uniprot id: B8I1M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

394503:CCEL RS00910
gene id: 394503:CCEL_RS00910
uniprot id: B8I4L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

394503:CCEL RS17340
gene id: 394503:CCEL_RS17340
uniprot id: B8I1V7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS17520
gene id: 394503:CCEL_RS17520
uniprot id: B8I2B0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS08495
gene id: 394503:CCEL_RS08495
uniprot id: B8I2P2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

394503:CCEL RS01560
gene id: 394503:CCEL_RS01560
uniprot id: B8I5N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

394503:CCEL RS00245
gene id: 394503:CCEL_RS00245
uniprot id: B8I3V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS14780
gene id: 394503:CCEL_RS14780
uniprot id: B8I8C8
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS08545
gene id: 394503:CCEL_RS08545
uniprot id: B8I2Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

394503:CCEL RS14610
gene id: 394503:CCEL_RS14610
uniprot id: B8I894
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

394503:CCEL RS01415
gene id: 394503:CCEL_RS01415
uniprot id: B8I590
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

394503:CCEL RS15535
gene id: 394503:CCEL_RS15535
uniprot id: B8I056
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

394503:CCEL RS02505
gene id: 394503:CCEL_RS02505
uniprot id: B8I6I8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

394503:CCEL RS04015
gene id: 394503:CCEL_RS04015
uniprot id: B8I810
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

394503:CCEL RS11655
gene id: 394503:CCEL_RS11655
uniprot id: B8I4Y8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

394503:CCEL RS01285
gene id: 394503:CCEL_RS01285
uniprot id: B8I564
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

394503:CCEL RS11470
gene id: 394503:CCEL_RS11470
uniprot id: B8I4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

394503:CCEL RS02235
gene id: 394503:CCEL_RS02235
uniprot id: B8I6D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS10465
gene id: 394503:CCEL_RS10465
uniprot id: B8I3Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

394503:CCEL RS10710
gene id: 394503:CCEL_RS10710
uniprot id: B8I429
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS04525
gene id: 394503:CCEL_RS04525
uniprot id: B8I8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS15385
gene id: 394503:CCEL_RS15385
uniprot id: B8I919
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

394503:CCEL RS08605
gene id: 394503:CCEL_RS08605
uniprot id: B8I2R4
names: Similarity
messages: Belongs to the peptidase M16 family.

394503:CCEL RS01340
gene id: 394503:CCEL_RS01340
uniprot id: B8I575
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

394503:CCEL RS03420
gene id: 394503:CCEL_RS03420
uniprot id: B8I7C8
names: Similarity
messages: Belongs to the thioesterase family.

394503:CCEL RS12540
gene id: 394503:CCEL_RS12540
uniprot id: B8I640
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS03200
gene id: 394503:CCEL_RS03200
uniprot id: B8I787
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

394503:CCEL RS06140
gene id: 394503:CCEL_RS06140
uniprot id: B8I0K6
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS10970
gene id: 394503:CCEL_RS10970
uniprot id: B8I481
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS10850
gene id: 394503:CCEL_RS10850
uniprot id: B8I456
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS03015
gene id: 394503:CCEL_RS03015
uniprot id: B8I750
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

394503:CCEL RS15520
gene id: 394503:CCEL_RS15520
uniprot id: B8I053
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS17360
gene id: 394503:CCEL_RS17360
uniprot id: B8I284
names: Similarity
messages: Belongs to the peptidase M29 family.

394503:CCEL RS10575
gene id: 394503:CCEL_RS10575
uniprot id: B8I402
names: Similarity
messages: Belongs to the peptidase C56 family.

394503:CCEL RS06305
gene id: 394503:CCEL_RS06305
uniprot id: B8I0N9
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

394503:CCEL RS13440
gene id: 394503:CCEL_RS13440
uniprot id: B8I6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

394503:CCEL RS16660
gene id: 394503:CCEL_RS16660
uniprot id: B8I155
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

394503:CCEL RS03625
gene id: 394503:CCEL_RS03625
uniprot id: B8I7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

394503:CCEL RS01165
gene id: 394503:CCEL_RS01165
uniprot id: Q0PRN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

394503:CCEL RS08390
gene id: 394503:CCEL_RS08390
uniprot id: B8I2M1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

394503:CCEL RS00450
gene id: 394503:CCEL_RS00450
uniprot id: B8I4C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

394503:CCEL RS11745
gene id: 394503:CCEL_RS11745
uniprot id: B8I5C4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS14680
gene id: 394503:CCEL_RS14680
uniprot id: B8I8A8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS10815
gene id: 394503:CCEL_RS10815
uniprot id: B8I450
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

394503:CCEL RS17465
gene id: 394503:CCEL_RS17465
uniprot id: B8I2A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

394503:CCEL RS03135
gene id: 394503:CCEL_RS03135
uniprot id: B8I774
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

394503:CCEL RS03105
gene id: 394503:CCEL_RS03105
uniprot id: B8I768
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

394503:CCEL RS10775
gene id: 394503:CCEL_RS10775
uniprot id: B8I442
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

394503:CCEL RS05600
gene id: 394503:CCEL_RS05600
uniprot id: B8HZX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

394503:CCEL RS11325
gene id: 394503:CCEL_RS11325
uniprot id: B8I4S8
names: Similarity
messages: Belongs to the UPF0297 family.

394503:CCEL RS09350
gene id: 394503:CCEL_RS09350
uniprot id: B8I354
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

394503:CCEL RS08945
gene id: 394503:CCEL_RS08945
uniprot id: B8I2X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

394503:CCEL RS10100
gene id: 394503:CCEL_RS10100
uniprot id: B8I3K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

394503:CCEL RS02675
gene id: 394503:CCEL_RS02675
uniprot id: B8I6L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

394503:CCEL RS15570
gene id: 394503:CCEL_RS15570
uniprot id: B8I063
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

394503:CCEL RS02290
gene id: 394503:CCEL_RS02290
uniprot id: B8I6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

394503:CCEL RS03030
gene id: 394503:CCEL_RS03030
uniprot id: B8I753
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

394503:CCEL RS16860
gene id: 394503:CCEL_RS16860
uniprot id: B8I1L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

394503:CCEL RS17450
gene id: 394503:CCEL_RS17450
uniprot id: B8I2A2
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

394503:CCEL RS15055
gene id: 394503:CCEL_RS15055
uniprot id: B8I8V2
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS10410
gene id: 394503:CCEL_RS10410
uniprot id: B8I3X2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

394503:CCEL RS02465
gene id: 394503:CCEL_RS02465
uniprot id: B8I6I0
names: Similarity
messages: Belongs to the UPF0229 family.

394503:CCEL RS03920
gene id: 394503:CCEL_RS03920
uniprot id: B8I7Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

394503:CCEL RS17335
gene id: 394503:CCEL_RS17335
uniprot id: B8I1V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

394503:CCEL RS17535
gene id: 394503:CCEL_RS17535
uniprot id: B8I2B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

394503:CCEL RS05575
gene id: 394503:CCEL_RS05575
uniprot id: B8HZX0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

394503:CCEL RS01840
gene id: 394503:CCEL_RS01840
uniprot id: B8I5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

394503:CCEL RS18885
gene id: 394503:CCEL_RS18885
uniprot id: B8I0X3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS02825
gene id: 394503:CCEL_RS02825
uniprot id: B8I717
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS03885
gene id: 394503:CCEL_RS03885
uniprot id: B8I7Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

394503:CCEL RS06905
gene id: 394503:CCEL_RS06905
uniprot id: B8I1C9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS14190
gene id: 394503:CCEL_RS14190
uniprot id: B8I7P2
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS14825
gene id: 394503:CCEL_RS14825
uniprot id: B8I8D7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS09850
gene id: 394503:CCEL_RS09850
uniprot id: B8I3F0
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

394503:CCEL RS01065
gene id: 394503:CCEL_RS01065
uniprot id: B8I519
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

394503:CCEL RS09075
gene id: 394503:CCEL_RS09075
uniprot id: B8I303
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

394503:CCEL RS13025
gene id: 394503:CCEL_RS13025
uniprot id: B8I6R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

394503:CCEL RS07110
gene id: 394503:CCEL_RS07110
uniprot id: B8I1H0
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS04000
gene id: 394503:CCEL_RS04000
uniprot id: B8I807
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

394503:CCEL RS17500
gene id: 394503:CCEL_RS17500
uniprot id: B8I2A6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

394503:CCEL RS07200
gene id: 394503:CCEL_RS07200
uniprot id: B8I1I7
names: Similarity
messages: Belongs to the aldose epimerase family.

394503:CCEL RS04985
gene id: 394503:CCEL_RS04985
uniprot id: B8I994
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

394503:CCEL RS06155
gene id: 394503:CCEL_RS06155
uniprot id: B8I0K9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS01910
gene id: 394503:CCEL_RS01910
uniprot id: B8I5V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

394503:CCEL RS14745
gene id: 394503:CCEL_RS14745
uniprot id: B8I8C1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS04930
gene id: 394503:CCEL_RS04930
uniprot id: B8I983
names: Similarity
messages: Belongs to the group II decarboxylase family.

394503:CCEL RS10650
gene id: 394503:CCEL_RS10650
uniprot id: B8I417
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

394503:CCEL RS06380
gene id: 394503:CCEL_RS06380
uniprot id: B8I0Q3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

394503:CCEL RS01000
gene id: 394503:CCEL_RS01000
uniprot id: B8I505
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS02685
gene id: 394503:CCEL_RS02685
uniprot id: B8I6M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

394503:CCEL RS00200
gene id: 394503:CCEL_RS00200
uniprot id: B8I3U9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

394503:CCEL RS00665
gene id: 394503:CCEL_RS00665
uniprot id: B8I4G6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

394503:CCEL RS00645
gene id: 394503:CCEL_RS00645
uniprot id: B8I4G2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS09425
gene id: 394503:CCEL_RS09425
uniprot id: B8I368
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS09820
gene id: 394503:CCEL_RS09820
uniprot id: B8I3E5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

394503:CCEL RS10255
gene id: 394503:CCEL_RS10255
uniprot id: B8I3N1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

394503:CCEL RS02935
gene id: 394503:CCEL_RS02935
uniprot id: B8I733
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

394503:CCEL RS08540
gene id: 394503:CCEL_RS08540
uniprot id: B8I2Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

394503:CCEL RS07230
gene id: 394503:CCEL_RS07230
uniprot id: B8I1W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

394503:CCEL RS08855
gene id: 394503:CCEL_RS08855
uniprot id: B8I2W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

394503:CCEL RS11670
gene id: 394503:CCEL_RS11670
uniprot id: B8I4Z1
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS13870
gene id: 394503:CCEL_RS13870
uniprot id: B8I7I4
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS00530
gene id: 394503:CCEL_RS00530
uniprot id: B8I4D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

394503:CCEL RS16125
gene id: 394503:CCEL_RS16125
uniprot id: B8I0U9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

394503:CCEL RS14650
gene id: 394503:CCEL_RS14650
uniprot id: B8I8A2
names: Similarity
messages: Belongs to the CdaR family.

394503:CCEL RS12220
gene id: 394503:CCEL_RS12220
uniprot id: B8I5L0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

394503:CCEL RS16340
gene id: 394503:CCEL_RS16340
uniprot id: B8I0Z2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

394503:CCEL RS07840
gene id: 394503:CCEL_RS07840
uniprot id: B8I278
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS00740
gene id: 394503:CCEL_RS00740
uniprot id: B8I4I1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS04605
gene id: 394503:CCEL_RS04605
uniprot id: B8I8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS12825
gene id: 394503:CCEL_RS12825
uniprot id: B8I697
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

394503:CCEL RS04140
gene id: 394503:CCEL_RS04140
uniprot id: B8I8F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

394503:CCEL RS02680
gene id: 394503:CCEL_RS02680
uniprot id: B8I6M0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

394503:CCEL RS09885
gene id: 394503:CCEL_RS09885
uniprot id: B8I3F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS09615
gene id: 394503:CCEL_RS09615
uniprot id: B8I3A4
names: Similarity
messages: Belongs to the TlyA family.

394503:CCEL RS00030
gene id: 394503:CCEL_RS00030
uniprot id: B8I3R7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

394503:CCEL RS09080
gene id: 394503:CCEL_RS09080
uniprot id: B8I304
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

394503:CCEL RS14265
gene id: 394503:CCEL_RS14265
uniprot id: B8I829
names: Similarity
messages: Belongs to the peptidase S14 family.

394503:CCEL RS03130
gene id: 394503:CCEL_RS03130
uniprot id: B8I773
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS07310
gene id: 394503:CCEL_RS07310
uniprot id: B8I1X8
names: Similarity
messages: Belongs to the threonine synthase family.

394503:CCEL RS02955
gene id: 394503:CCEL_RS02955
uniprot id: B8I738
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

394503:CCEL RS10500
gene id: 394503:CCEL_RS10500
uniprot id: B8I3Y9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

394503:CCEL RS00290
gene id: 394503:CCEL_RS00290
uniprot id: B8I3W6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

394503:CCEL RS03900
gene id: 394503:CCEL_RS03900
uniprot id: B8I7Y7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

394503:CCEL RS15075
gene id: 394503:CCEL_RS15075
uniprot id: B8I8V6
names: Similarity
messages: Belongs to the UPF0178 family.

394503:CCEL RS06410
gene id: 394503:CCEL_RS06410
uniprot id: B8I0Q9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

394503:CCEL RS16145
gene id: 394503:CCEL_RS16145
uniprot id: B8I0V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

394503:CCEL RS17435
gene id: 394503:CCEL_RS17435
uniprot id: B8I299
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

394503:CCEL RS07710
gene id: 394503:CCEL_RS07710
uniprot id: B8I254
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

394503:CCEL RS11565
gene id: 394503:CCEL_RS11565
uniprot id: B8I4X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

394503:CCEL RS06590
gene id: 394503:CCEL_RS06590
uniprot id: B8I169
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

394503:CCEL RS00390
gene id: 394503:CCEL_RS00390
uniprot id: B8I4A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

394503:CCEL RS06310
gene id: 394503:CCEL_RS06310
uniprot id: B8I0P0
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

394503:CCEL RS10720
gene id: 394503:CCEL_RS10720
uniprot id: B8I431
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

394503:CCEL RS03390
gene id: 394503:CCEL_RS03390
uniprot id: B8I7C2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

394503:CCEL RS01530
gene id: 394503:CCEL_RS01530
uniprot id: B8I5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

394503:CCEL RS16155
gene id: 394503:CCEL_RS16155
uniprot id: B8I0V5
names: Similarity
messages: Belongs to the hexokinase family.

394503:CCEL RS05955
gene id: 394503:CCEL_RS05955
uniprot id: B8I045
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

394503:CCEL RS09855
gene id: 394503:CCEL_RS09855
uniprot id: B8I3F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS02425
gene id: 394503:CCEL_RS02425
uniprot id: B8I6H2
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS01925
gene id: 394503:CCEL_RS01925
uniprot id: B8I5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

394503:CCEL RS17225
gene id: 394503:CCEL_RS17225
uniprot id: B8I1T4
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

394503:CCEL RS06365
gene id: 394503:CCEL_RS06365
uniprot id: B8I0Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

394503:CCEL RS13465
gene id: 394503:CCEL_RS13465
uniprot id: B8I6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

394503:CCEL RS03985
gene id: 394503:CCEL_RS03985
uniprot id: B8I804
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

394503:CCEL RS01640
gene id: 394503:CCEL_RS01640
uniprot id: B8I5P8
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

394503:CCEL RS06900
gene id: 394503:CCEL_RS06900
uniprot id: B8I1C8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS03860
gene id: 394503:CCEL_RS03860
uniprot id: B8I7X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

394503:CCEL RS13080
gene id: 394503:CCEL_RS13080
uniprot id: B8I6S2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

394503:CCEL RS00660
gene id: 394503:CCEL_RS00660
uniprot id: B8I4G5
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

394503:CCEL RS16320
gene id: 394503:CCEL_RS16320
uniprot id: B8I0Y8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

394503:CCEL RS16925
gene id: 394503:CCEL_RS16925
uniprot id: B8I1M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

394503:CCEL RS02570
gene id: 394503:CCEL_RS02570
uniprot id: B8I6K2
names: Similarity
messages: Belongs to the peptidase A24 family.

394503:CCEL RS14730
gene id: 394503:CCEL_RS14730
uniprot id: B8I8B8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

394503:CCEL RS11555
gene id: 394503:CCEL_RS11555
uniprot id: B8I4X0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

394503:CCEL RS10305
gene id: 394503:CCEL_RS10305
uniprot id: B8I3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

394503:CCEL RS10120
gene id: 394503:CCEL_RS10120
uniprot id: B8I3K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

394503:CCEL RS01295
gene id: 394503:CCEL_RS01295
uniprot id: B8I566
names: Similarity
messages: Belongs to the LacAB/RpiB family.

394503:CCEL RS09810
gene id: 394503:CCEL_RS09810
uniprot id: B8I3E3
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS00870
gene id: 394503:CCEL_RS00870
uniprot id: B8I4K7
names: Similarity
messages: Belongs to the hemerythrin family.

394503:CCEL RS17220
gene id: 394503:CCEL_RS17220
uniprot id: B8I1T3
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

394503:CCEL RS11725
gene id: 394503:CCEL_RS11725
uniprot id: B8I5C0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

394503:CCEL RS11705
gene id: 394503:CCEL_RS11705
uniprot id: B8I5B6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS11650
gene id: 394503:CCEL_RS11650
uniprot id: B8I4Y7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

394503:CCEL RS07150
gene id: 394503:CCEL_RS07150
uniprot id: B8I1H7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS05375
gene id: 394503:CCEL_RS05375
uniprot id: B8HZT0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

394503:CCEL RS02390
gene id: 394503:CCEL_RS02390
uniprot id: B8I6G5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

394503:CCEL RS06565
gene id: 394503:CCEL_RS06565
uniprot id: B8I0T7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS16885
gene id: 394503:CCEL_RS16885
uniprot id: B8I1M1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

394503:CCEL RS06465
gene id: 394503:CCEL_RS06465
uniprot id: B8I0S0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

394503:CCEL RS09640
gene id: 394503:CCEL_RS09640
uniprot id: B8I3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

394503:CCEL RS11615
gene id: 394503:CCEL_RS11615
uniprot id: B8I4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

394503:CCEL RS17270
gene id: 394503:CCEL_RS17270
uniprot id: B8I1U3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

394503:CCEL RS11050
gene id: 394503:CCEL_RS11050
uniprot id: B8I4M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS04075
gene id: 394503:CCEL_RS04075
uniprot id: B8I822
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

394503:CCEL RS06300
gene id: 394503:CCEL_RS06300
uniprot id: B8I0N8
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS11220
gene id: 394503:CCEL_RS11220
uniprot id: B8I4Q7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

394503:CCEL RS11495
gene id: 394503:CCEL_RS11495
uniprot id: B8I4V8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

394503:CCEL RS00270
gene id: 394503:CCEL_RS00270
uniprot id: B8I3W2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

394503:CCEL RS03115
gene id: 394503:CCEL_RS03115
uniprot id: B8I770
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

394503:CCEL RS02355
gene id: 394503:CCEL_RS02355
uniprot id: B8I6F7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS00185
gene id: 394503:CCEL_RS00185
uniprot id: B8I3U6
names: Similarity
messages: Belongs to the SleB family.

394503:CCEL RS07830
gene id: 394503:CCEL_RS07830
uniprot id: B8I276
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

394503:CCEL RS06215
gene id: 394503:CCEL_RS06215
uniprot id: B8I0M1
names: Subcellular Location Annotation
messages: Secreted

394503:CCEL RS04400
gene id: 394503:CCEL_RS04400
uniprot id: B8I8K5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

394503:CCEL RS17460
gene id: 394503:CCEL_RS17460
uniprot id: B8I2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

394503:CCEL RS11200
gene id: 394503:CCEL_RS11200
uniprot id: B8I4Q3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

394503:CCEL RS10425
gene id: 394503:CCEL_RS10425
uniprot id: B8I3X5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

394503:CCEL RS01920
gene id: 394503:CCEL_RS01920
uniprot id: B8I5V4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

394503:CCEL RS10265
gene id: 394503:CCEL_RS10265
uniprot id: B8I3N3
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

394503:CCEL RS01890
gene id: 394503:CCEL_RS01890
uniprot id: B8I5U8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

394503:CCEL RS09590
gene id: 394503:CCEL_RS09590
uniprot id: B8I399
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS10680
gene id: 394503:CCEL_RS10680
uniprot id: B8I423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS09980
gene id: 394503:CCEL_RS09980
uniprot id: B8I3H7
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS16930
gene id: 394503:CCEL_RS16930
uniprot id: B8I1N0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS02340
gene id: 394503:CCEL_RS02340
uniprot id: B8I6F4
names: Similarity
messages: Belongs to the HypD family.

394503:CCEL RS11320
gene id: 394503:CCEL_RS11320
uniprot id: B8I4S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

394503:CCEL RS03755
gene id: 394503:CCEL_RS03755
uniprot id: B8I7W2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

394503:CCEL RS06595
gene id: 394503:CCEL_RS06595
uniprot id: B8I170
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

394503:CCEL RS16140
gene id: 394503:CCEL_RS16140
uniprot id: B8I0V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

394503:CCEL RS07655
gene id: 394503:CCEL_RS07655
uniprot id: B8I247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

394503:CCEL RS12720
gene id: 394503:CCEL_RS12720
uniprot id: B8I676
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

394503:CCEL RS02385
gene id: 394503:CCEL_RS02385
uniprot id: B8I6G4
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS04690
gene id: 394503:CCEL_RS04690
uniprot id: B8I8R2
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS08085
gene id: 394503:CCEL_RS08085
uniprot id: B8I2G0
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

394503:CCEL RS02345
gene id: 394503:CCEL_RS02345
uniprot id: B8I6F5
names: Similarity
messages: Belongs to the HypE family.

394503:CCEL RS02230
gene id: 394503:CCEL_RS02230
uniprot id: B8I6D2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

394503:CCEL RS10625
gene id: 394503:CCEL_RS10625
uniprot id: B8I412
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

394503:CCEL RS00515
gene id: 394503:CCEL_RS00515
uniprot id: B8I4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

394503:CCEL RS06985
gene id: 394503:CCEL_RS06985
uniprot id: B8I1E5
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

394503:CCEL RS09860
gene id: 394503:CCEL_RS09860
uniprot id: B8I3F2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS08670
gene id: 394503:CCEL_RS08670
uniprot id: B8I2S7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS05800
gene id: 394503:CCEL_RS05800
uniprot id: B8I014
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS03545
gene id: 394503:CCEL_RS03545
uniprot id: B8I7R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

394503:CCEL RS03880
gene id: 394503:CCEL_RS03880
uniprot id: B8I7Y3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

394503:CCEL RS03950
gene id: 394503:CCEL_RS03950
uniprot id: B8I7Z7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

394503:CCEL RS05960
gene id: 394503:CCEL_RS05960
uniprot id: B8I0H1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

394503:CCEL RS02405
gene id: 394503:CCEL_RS02405
uniprot id: B8I6G8
names: Similarity
messages: Belongs to the transpeptidase family.

394503:CCEL RS04620
gene id: 394503:CCEL_RS04620
uniprot id: B8I8P9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

394503:CCEL RS04695
gene id: 394503:CCEL_RS04695
uniprot id: B8I8R3
names: Similarity
messages: Belongs to the alkaline phosphatase family.

394503:CCEL RS01585
gene id: 394503:CCEL_RS01585
uniprot id: B8I5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

394503:CCEL RS07410
gene id: 394503:CCEL_RS07410
uniprot id: B8I1Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

394503:CCEL RS03970
gene id: 394503:CCEL_RS03970
uniprot id: B8I801
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

394503:CCEL RS05695
gene id: 394503:CCEL_RS05695
uniprot id: B8HZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS10270
gene id: 394503:CCEL_RS10270
uniprot id: B8I3N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

394503:CCEL RS06530
gene id: 394503:CCEL_RS06530
uniprot id: B8I0T0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

394503:CCEL RS05510
gene id: 394503:CCEL_RS05510
uniprot id: P17901
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: The C-terminus (AA 411-475) may play a role in organizing the cellulosome complex.
messages: The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.

394503:CCEL RS16255
gene id: 394503:CCEL_RS16255
uniprot id: B8I0X5
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

394503:CCEL RS16270
gene id: 394503:CCEL_RS16270
uniprot id: B8I0X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS10655
gene id: 394503:CCEL_RS10655
uniprot id: B8I418
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS06750
gene id: 394503:CCEL_RS06750
uniprot id: B8I1A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

394503:CCEL RS13255
gene id: 394503:CCEL_RS13255
uniprot id: B8I6V7
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

394503:CCEL RS11255
gene id: 394503:CCEL_RS11255
uniprot id: B8I4R4
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

394503:CCEL RS06775
gene id: 394503:CCEL_RS06775
uniprot id: B8I1A5
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

394503:CCEL RS12965
gene id: 394503:CCEL_RS12965
uniprot id: B8I6P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

394503:CCEL RS04965
gene id: 394503:CCEL_RS04965
uniprot id: B8I990
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

394503:CCEL RS12940
gene id: 394503:CCEL_RS12940
uniprot id: B8I6C1
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

394503:CCEL RS06170
gene id: 394503:CCEL_RS06170
uniprot id: B8I0L2
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS13210
gene id: 394503:CCEL_RS13210
uniprot id: B8I6U9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

394503:CCEL RS08815
gene id: 394503:CCEL_RS08815
uniprot id: B8I2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

394503:CCEL RS10400
gene id: 394503:CCEL_RS10400
uniprot id: B8I3R0
names: Similarity
messages: Belongs to the DprA/Smf family.

394503:CCEL RS06260
gene id: 394503:CCEL_RS06260
uniprot id: B8I0N0
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

394503:CCEL RS09770
gene id: 394503:CCEL_RS09770
uniprot id: B8I3D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS00880
gene id: 394503:CCEL_RS00880
uniprot id: B8I4K9
names: Similarity
messages: Belongs to the phosphopentomutase family.

394503:CCEL RS05925
gene id: 394503:CCEL_RS05925
uniprot id: B8I039
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS06120
gene id: 394503:CCEL_RS06120
uniprot id: B8I0K2
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

394503:CCEL RS01850
gene id: 394503:CCEL_RS01850
uniprot id: B8I5U0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

394503:CCEL RS02960
gene id: 394503:CCEL_RS02960
uniprot id: B8I739
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

394503:CCEL RS12715
gene id: 394503:CCEL_RS12715
uniprot id: B8I675
names: Similarity
messages: Belongs to the thioesterase family.

394503:CCEL RS11995
gene id: 394503:CCEL_RS11995
uniprot id: B8I5H4
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

394503:CCEL RS06040
gene id: 394503:CCEL_RS06040
uniprot id: B8I0I6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

394503:CCEL RS08335
gene id: 394503:CCEL_RS08335
uniprot id: B8I2L0
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS14790
gene id: 394503:CCEL_RS14790
uniprot id: B8I8D0
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS01580
gene id: 394503:CCEL_RS01580
uniprot id: B8I5N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

394503:CCEL RS11040
gene id: 394503:CCEL_RS11040
uniprot id: B8I493
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

394503:CCEL RS08200
gene id: 394503:CCEL_RS08200
uniprot id: B8I2I3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

394503:CCEL RS10440
gene id: 394503:CCEL_RS10440
uniprot id: B8I3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

394503:CCEL RS04515
gene id: 394503:CCEL_RS04515
uniprot id: B8I8M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

394503:CCEL RS04030
gene id: 394503:CCEL_RS04030
uniprot id: B8I813
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component). May be able to interact with more than 1 S component at a time (By similarity).
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

394503:CCEL RS10015
gene id: 394503:CCEL_RS10015
uniprot id: B8I3I3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

394503:CCEL RS12085
gene id: 394503:CCEL_RS12085
uniprot id: B8I5J1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS12445
gene id: 394503:CCEL_RS12445
uniprot id: B8I621
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS05625
gene id: 394503:CCEL_RS05625
uniprot id: B8HZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS11340
gene id: 394503:CCEL_RS11340
uniprot id: B8I4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

394503:CCEL RS08880
gene id: 394503:CCEL_RS08880
uniprot id: B8I2W8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

394503:CCEL RS03360
gene id: 394503:CCEL_RS03360
uniprot id: B8I7B6
names: Similarity
messages: Belongs to the helicase family. RAD3/XPD subfamily.

394503:CCEL RS08445
gene id: 394503:CCEL_RS08445
uniprot id: B8I2N2
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

394503:CCEL RS02905
gene id: 394503:CCEL_RS02905
uniprot id: B8I727
names: Similarity
messages: Belongs to the UPF0749 family.

394503:CCEL RS17255
gene id: 394503:CCEL_RS17255
uniprot id: B8I1U0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

394503:CCEL RS01330
gene id: 394503:CCEL_RS01330
uniprot id: B8I573
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

394503:CCEL RS01965
gene id: 394503:CCEL_RS01965
uniprot id: B8I5W3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

394503:CCEL RS11720
gene id: 394503:CCEL_RS11720
uniprot id: B8I5B9
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

394503:CCEL RS17505
gene id: 394503:CCEL_RS17505
uniprot id: B8I2A7
names: Similarity
messages: Belongs to the ParB family.

394503:CCEL RS04035
gene id: 394503:CCEL_RS04035
uniprot id: B8I814
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

394503:CCEL RS00570
gene id: 394503:CCEL_RS00570
uniprot id: B8I4E4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

394503:CCEL RS15590
gene id: 394503:CCEL_RS15590
uniprot id: B8I067
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

394503:CCEL RS15540
gene id: 394503:CCEL_RS15540
uniprot id: B8I057
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

394503:CCEL RS13160
gene id: 394503:CCEL_RS13160
uniprot id: B8I6T9
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Homodimer.

394503:CCEL RS04130
gene id: 394503:CCEL_RS04130
uniprot id: B8I8F7
names: Similarity
messages: Belongs to the peptidase S16 family.

394503:CCEL RS08310
gene id: 394503:CCEL_RS08310
uniprot id: B8I2K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

394503:CCEL RS03245
gene id: 394503:CCEL_RS03245
uniprot id: B8I795
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

394503:CCEL RS12435
gene id: 394503:CCEL_RS12435
uniprot id: B8I619
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

394503:CCEL RS16665
gene id: 394503:CCEL_RS16665
uniprot id: B8I156
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS12185
gene id: 394503:CCEL_RS12185
uniprot id: B8I5K7
names: Similarity
messages: Belongs to the GSP E family.

394503:CCEL RS03265
gene id: 394503:CCEL_RS03265
uniprot id: B8I799
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

394503:CCEL RS08475
gene id: 394503:CCEL_RS08475
uniprot id: B8I2N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS06575
gene id: 394503:CCEL_RS06575
uniprot id: B8I0T9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

394503:CCEL RS05750
gene id: 394503:CCEL_RS05750
uniprot id: B8I004
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

394503:CCEL RS10540
gene id: 394503:CCEL_RS10540
uniprot id: B8I3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS01700
gene id: 394503:CCEL_RS01700
uniprot id: B8I5R0
names: Similarity
messages: Belongs to the ycf81 family.

394503:CCEL RS06180
gene id: 394503:CCEL_RS06180
uniprot id: B8I0L4
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS13030
gene id: 394503:CCEL_RS13030
uniprot id: B8I6R2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

394503:CCEL RS11675
gene id: 394503:CCEL_RS11675
uniprot id: B8I4Z2
names: Similarity
messages: Belongs to the ArsC family.

394503:CCEL RS03485
gene id: 394503:CCEL_RS03485
uniprot id: B8I7Q8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

394503:CCEL RS01215
gene id: 394503:CCEL_RS01215
uniprot id: B8I549
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

394503:CCEL RS09580
gene id: 394503:CCEL_RS09580
uniprot id: B8I397
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS05995
gene id: 394503:CCEL_RS05995
uniprot id: B8I0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

394503:CCEL RS01230
gene id: 394503:CCEL_RS01230
uniprot id: B8I553
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS02695
gene id: 394503:CCEL_RS02695
uniprot id: B8I6M4
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

394503:CCEL RS08970
gene id: 394503:CCEL_RS08970
uniprot id: B8I2Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

394503:CCEL RS06630
gene id: 394503:CCEL_RS06630
uniprot id: B8I176
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

394503:CCEL RS10905
gene id: 394503:CCEL_RS10905
uniprot id: B8I467
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS00265
gene id: 394503:CCEL_RS00265
uniprot id: B8I3W1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

394503:CCEL RS04080
gene id: 394503:CCEL_RS04080
uniprot id: B8I823
names: Similarity
messages: Belongs to the peptidase S16 family.

394503:CCEL RS09900
gene id: 394503:CCEL_RS09900
uniprot id: B8I3G0
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS05100
gene id: 394503:CCEL_RS05100
uniprot id: B8I9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS08550
gene id: 394503:CCEL_RS08550
uniprot id: B8I2Q3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

394503:CCEL RS02445
gene id: 394503:CCEL_RS02445
uniprot id: B8I6H6
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

394503:CCEL RS07495
gene id: 394503:CCEL_RS07495
uniprot id: B8I213
names: Similarity
messages: Belongs to the transpeptidase family.

394503:CCEL RS11475
gene id: 394503:CCEL_RS11475
uniprot id: B8I4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

394503:CCEL RS16955
gene id: 394503:CCEL_RS16955
uniprot id: B8I1N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

394503:CCEL RS14800
gene id: 394503:CCEL_RS14800
uniprot id: B8I8D2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

394503:CCEL RS16075
gene id: 394503:CCEL_RS16075
uniprot id: B8I0G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

394503:CCEL RS12470
gene id: 394503:CCEL_RS12470
uniprot id: B8I626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS17095
gene id: 394503:CCEL_RS17095
uniprot id: B8I1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

394503:CCEL RS09570
gene id: 394503:CCEL_RS09570
uniprot id: B8I395
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

394503:CCEL RS07565
gene id: 394503:CCEL_RS07565
uniprot id: B8I227
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

394503:CCEL RS09395
gene id: 394503:CCEL_RS09395
uniprot id: B8I362
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

394503:CCEL RS12290
gene id: 394503:CCEL_RS12290
uniprot id: B8I5L9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS03995
gene id: 394503:CCEL_RS03995
uniprot id: B8I806
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

394503:CCEL RS13000
gene id: 394503:CCEL_RS13000
uniprot id: B8I6Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

394503:CCEL RS12945
gene id: 394503:CCEL_RS12945
uniprot id: B8I6C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

394503:CCEL RS13075
gene id: 394503:CCEL_RS13075
uniprot id: B8I6S1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

394503:CCEL RS11960
gene id: 394503:CCEL_RS11960
uniprot id: B8I5G7
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

394503:CCEL RS11505
gene id: 394503:CCEL_RS11505
uniprot id: B8I4W0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

394503:CCEL RS06205
gene id: 394503:CCEL_RS06205
uniprot id: Q0PRN1
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

394503:CCEL RS06570
gene id: 394503:CCEL_RS06570
uniprot id: B8I0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS08560
gene id: 394503:CCEL_RS08560
uniprot id: B8I2Q5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

394503:CCEL RS03750
gene id: 394503:CCEL_RS03750
uniprot id: B8I7W1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

394503:CCEL RS10275
gene id: 394503:CCEL_RS10275
uniprot id: B8I3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

394503:CCEL RS07100
gene id: 394503:CCEL_RS07100
uniprot id: B8I1G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

394503:CCEL RS03640
gene id: 394503:CCEL_RS03640
uniprot id: B8I7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

394503:CCEL RS14045
gene id: 394503:CCEL_RS14045
uniprot id: B8I7L4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

394503:CCEL RS00460
gene id: 394503:CCEL_RS00460
uniprot id: B8I4C3
names: Caution
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS16080
gene id: 394503:CCEL_RS16080
uniprot id: B8I0H0
names: Similarity
messages: Belongs to the CapA family.

394503:CCEL RS06015
gene id: 394503:CCEL_RS06015
uniprot id: B8I0I2
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

394503:CCEL RS06355
gene id: 394503:CCEL_RS06355
uniprot id: B8I0P8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

394503:CCEL RS06420
gene id: 394503:CCEL_RS06420
uniprot id: B8I0R1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS01455
gene id: 394503:CCEL_RS01455
uniprot id: B8I598
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

394503:CCEL RS10035
gene id: 394503:CCEL_RS10035
uniprot id: B8I3I7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS07125
gene id: 394503:CCEL_RS07125
uniprot id: B8I1H3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

394503:CCEL RS05205
gene id: 394503:CCEL_RS05205
uniprot id: B8I9D8
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

394503:CCEL RS02705
gene id: 394503:CCEL_RS02705
uniprot id: B8I6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

394503:CCEL RS00545
gene id: 394503:CCEL_RS00545
uniprot id: B8I4D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

394503:CCEL RS03910
gene id: 394503:CCEL_RS03910
uniprot id: B8I7Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

394503:CCEL RS10765
gene id: 394503:CCEL_RS10765
uniprot id: B8I440
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

394503:CCEL RS05780
gene id: 394503:CCEL_RS05780
uniprot id: B8I010
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS15115
gene id: 394503:CCEL_RS15115
uniprot id: B8I8W4
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

394503:CCEL RS03005
gene id: 394503:CCEL_RS03005
uniprot id: B8I748
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS17235
gene id: 394503:CCEL_RS17235
uniprot id: B8I1T6
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

394503:CCEL RS07470
gene id: 394503:CCEL_RS07470
uniprot id: B8I208
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

394503:CCEL RS17055
gene id: 394503:CCEL_RS17055
uniprot id: Q9L385
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

394503:CCEL RS17050
gene id: 394503:CCEL_RS17050
uniprot id: B8I1Q3
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

394503:CCEL RS16130
gene id: 394503:CCEL_RS16130
uniprot id: B8I0V0
names: Similarity
messages: Belongs to the TrpC family.

394503:CCEL RS10405
gene id: 394503:CCEL_RS10405
uniprot id: B8I3R1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

394503:CCEL RS00780
gene id: 394503:CCEL_RS00780
uniprot id: B8I4I9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

394503:CCEL RS08555
gene id: 394503:CCEL_RS08555
uniprot id: B8I2Q4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

394503:CCEL RS01590
gene id: 394503:CCEL_RS01590
uniprot id: B8I5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

394503:CCEL RS14005
gene id: 394503:CCEL_RS14005
uniprot id: B8I7K6
names: Similarity
messages: Belongs to the peptidase A24 family.

394503:CCEL RS08320
gene id: 394503:CCEL_RS08320
uniprot id: B8I2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS08780
gene id: 394503:CCEL_RS08780
uniprot id: B8I2U8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS01110
gene id: 394503:CCEL_RS01110
uniprot id: B8I528
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

394503:CCEL RS03610
gene id: 394503:CCEL_RS03610
uniprot id: B8I7T2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

394503:CCEL RS09750
gene id: 394503:CCEL_RS09750
uniprot id: B8I3D1
names: Similarity
messages: Belongs to the peptidase M18 family.

394503:CCEL RS17515
gene id: 394503:CCEL_RS17515
uniprot id: B8I2A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

394503:CCEL RS03035
gene id: 394503:CCEL_RS03035
uniprot id: B8I754
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

394503:CCEL RS00300
gene id: 394503:CCEL_RS00300
uniprot id: B8I3W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

394503:CCEL RS07440
gene id: 394503:CCEL_RS07440
uniprot id: B8I204
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

394503:CCEL RS05690
gene id: 394503:CCEL_RS05690
uniprot id: B8HZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS01260
gene id: 394503:CCEL_RS01260
uniprot id: B8I559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

394503:CCEL RS10025
gene id: 394503:CCEL_RS10025
uniprot id: B8I3I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

394503:CCEL RS15120
gene id: 394503:CCEL_RS15120
uniprot id: B8I8W5
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.
messages: Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man-Glc) to mannose 1-phosphate (Man1P) and glucose.

394503:CCEL RS09600
gene id: 394503:CCEL_RS09600
uniprot id: B8I3A1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

394503:CCEL RS11690
gene id: 394503:CCEL_RS11690
uniprot id: B8I4Z5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

394503:CCEL RS03195
gene id: 394503:CCEL_RS03195
uniprot id: B8I786
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

394503:CCEL RS09655
gene id: 394503:CCEL_RS09655
uniprot id: B8I3B2
names: Similarity
messages: Belongs to the asp23 family.

394503:CCEL RS16655
gene id: 394503:CCEL_RS16655
uniprot id: B8I154
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

394503:CCEL RS06335
gene id: 394503:CCEL_RS06335
uniprot id: B8I0P5
names: Similarity
messages: Belongs to the IlvD/Edd family.

394503:CCEL RS14630
gene id: 394503:CCEL_RS14630
uniprot id: B8I898
names: Similarity
messages: Belongs to the peptidase S41A family.

394503:CCEL RS03185
gene id: 394503:CCEL_RS03185
uniprot id: B8I784
names: Similarity
messages: Belongs to the UPF0251 family.

394503:CCEL RS03705
gene id: 394503:CCEL_RS03705
uniprot id: P37699
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.
messages: Monomer.
messages: The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
messages: There are two forms of the cellulase. The shorter form lacks probably the C-terminal reiterated domains.

394503:CCEL RS16910
gene id: 394503:CCEL_RS16910
uniprot id: B8I1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

394503:CCEL RS06950
gene id: 394503:CCEL_RS06950
uniprot id: B8I1D8
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

394503:CCEL RS16825
gene id: 394503:CCEL_RS16825
uniprot id: B8I1K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

394503:CCEL RS06760
gene id: 394503:CCEL_RS06760
uniprot id: B8I1A2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

394503:CCEL RS10175
gene id: 394503:CCEL_RS10175
uniprot id: B8I3L6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

394503:CCEL RS01005
gene id: 394503:CCEL_RS01005
uniprot id: B8I506
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS16745
gene id: 394503:CCEL_RS16745
uniprot id: B8I1J3
names: Similarity
messages: Belongs to the asp23 family.

394503:CCEL RS08995
gene id: 394503:CCEL_RS08995
uniprot id: B8I2Y7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

394503:CCEL RS00625
gene id: 394503:CCEL_RS00625
uniprot id: B8I4F8
names: Similarity
messages: Belongs to the DEAD box helicase family.

394503:CCEL RS08820
gene id: 394503:CCEL_RS08820
uniprot id: B8I2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS07320
gene id: 394503:CCEL_RS07320
uniprot id: B8I1Y0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

394503:CCEL RS12285
gene id: 394503:CCEL_RS12285
uniprot id: B8I5L8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

394503:CCEL RS01400
gene id: 394503:CCEL_RS01400
uniprot id: B8I587
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS09620
gene id: 394503:CCEL_RS09620
uniprot id: B8I3A5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

394503:CCEL RS08135
gene id: 394503:CCEL_RS08135
uniprot id: B8I2H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

394503:CCEL RS13215
gene id: 394503:CCEL_RS13215
uniprot id: B8I6V0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS16220
gene id: 394503:CCEL_RS16220
uniprot id: B8I0W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

394503:CCEL RS12305
gene id: 394503:CCEL_RS12305
uniprot id: B8I5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

394503:CCEL RS17245
gene id: 394503:CCEL_RS17245
uniprot id: B8I1T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

394503:CCEL RS08300
gene id: 394503:CCEL_RS08300
uniprot id: B8I2K3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS02140
gene id: 394503:CCEL_RS02140
uniprot id: B8I5Z1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

394503:CCEL RS08505
gene id: 394503:CCEL_RS08505
uniprot id: B8I2P4
names: Similarity
messages: Belongs to the FrhG family.

394503:CCEL RS10460
gene id: 394503:CCEL_RS10460
uniprot id: B8I3Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

394503:CCEL RS08645
gene id: 394503:CCEL_RS08645
uniprot id: B8I2S2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS10050
gene id: 394503:CCEL_RS10050
uniprot id: B8I3J0
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS08080
gene id: 394503:CCEL_RS08080
uniprot id: B8I2F9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

394503:CCEL RS12225
gene id: 394503:CCEL_RS12225
uniprot id: B8I5L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

394503:CCEL RS14455
gene id: 394503:CCEL_RS14455
uniprot id: B8I868
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

394503:CCEL RS04770
gene id: 394503:CCEL_RS04770
uniprot id: B8I950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS02760
gene id: 394503:CCEL_RS02760
uniprot id: B8I6N6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

394503:CCEL RS07810
gene id: 394503:CCEL_RS07810
uniprot id: B8I272
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS07650
gene id: 394503:CCEL_RS07650
uniprot id: B8I246
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

394503:CCEL RS10675
gene id: 394503:CCEL_RS10675
uniprot id: B8I422
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS04500
gene id: 394503:CCEL_RS04500
uniprot id: B8I8M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS03050
gene id: 394503:CCEL_RS03050
uniprot id: B8I757
names: Subcellular Location Annotation
messages: Cytoplasm

394503:CCEL RS02415
gene id: 394503:CCEL_RS02415
uniprot id: B8I6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

394503:CCEL RS00120
gene id: 394503:CCEL_RS00120
uniprot id: B8I3T3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

394503:CCEL RS12795
gene id: 394503:CCEL_RS12795
uniprot id: B8I691
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS02950
gene id: 394503:CCEL_RS02950
uniprot id: B8I736
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

394503:CCEL RS04800
gene id: 394503:CCEL_RS04800
uniprot id: B8I956
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

394503:CCEL RS15670
gene id: 394503:CCEL_RS15670
uniprot id: B8I085
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: Belongs to the CRISPR-associated protein Cas9 family. Subtype II-A subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

394503:CCEL RS17260
gene id: 394503:CCEL_RS17260
uniprot id: B8I1U1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

394503:CCEL RS04725
gene id: 394503:CCEL_RS04725
uniprot id: B8I942
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

394503:CCEL RS10635
gene id: 394503:CCEL_RS10635
uniprot id: B8I414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

394503:CCEL RS06800
gene id: 394503:CCEL_RS06800
uniprot id: B8I1B0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

394503:CCEL RS16875
gene id: 394503:CCEL_RS16875
uniprot id: B8I1L9
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

394503:CCEL RS10820
gene id: 394503:CCEL_RS10820
uniprot id: B8I451
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

394503:CCEL RS16770
gene id: 394503:CCEL_RS16770
uniprot id: B8I1J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

394503:CCEL RS05165
gene id: 394503:CCEL_RS05165
uniprot id: B8I9D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

394503:CCEL RS08020
gene id: 394503:CCEL_RS08020
uniprot id: B8I2C5
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

394503:CCEL RS01050
gene id: 394503:CCEL_RS01050
uniprot id: B8I516
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

394503:CCEL RS09385
gene id: 394503:CCEL_RS09385
uniprot id: B8I360
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

394503:CCEL RS05170
gene id: 394503:CCEL_RS05170
uniprot id: B8I9D1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

394503:CCEL RS17195
gene id: 394503:CCEL_RS17195
uniprot id: B8I1S8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

394503:CCEL RS11165
gene id: 394503:CCEL_RS11165
uniprot id: B8I4P6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

394503:CCEL RS03445
gene id: 394503:CCEL_RS03445
uniprot id: B8I7D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

394503:CCEL RS00995
gene id: 394503:CCEL_RS00995
uniprot id: B8I504
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS11025
gene id: 394503:CCEL_RS11025
uniprot id: B8I490
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

394503:CCEL RS08520
gene id: 394503:CCEL_RS08520
uniprot id: B8I2P7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS05605
gene id: 394503:CCEL_RS05605
uniprot id: B8HZX6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS12980
gene id: 394503:CCEL_RS12980
uniprot id: B8I6Q2
names: Similarity
messages: Belongs to the MecA family.

394503:CCEL RS10325
gene id: 394503:CCEL_RS10325
uniprot id: B8I3P5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

394503:CCEL RS03875
gene id: 394503:CCEL_RS03875
uniprot id: B8I7Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

394503:CCEL RS12075
gene id: 394503:CCEL_RS12075
uniprot id: B8I5I9
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

394503:CCEL RS10715
gene id: 394503:CCEL_RS10715
uniprot id: B8I430
names: Similarity
messages: Belongs to the UPF0111 family.

394503:CCEL RS05610
gene id: 394503:CCEL_RS05610
uniprot id: B8HZX7
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS03555
gene id: 394503:CCEL_RS03555
uniprot id: B8I7S1
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS03480
gene id: 394503:CCEL_RS03480
uniprot id: B8I7Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

394503:CCEL RS14495
gene id: 394503:CCEL_RS14495
uniprot id: B8I876
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

394503:CCEL RS09105
gene id: 394503:CCEL_RS09105
uniprot id: B8I309
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

394503:CCEL RS16240
gene id: 394503:CCEL_RS16240
uniprot id: B8I0X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS14715
gene id: 394503:CCEL_RS14715
uniprot id: B8I8B5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

394503:CCEL RS00435
gene id: 394503:CCEL_RS00435
uniprot id: B8I4B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

394503:CCEL RS03300
gene id: 394503:CCEL_RS03300
uniprot id: B8I7A6
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

394503:CCEL RS16915
gene id: 394503:CCEL_RS16915
uniprot id: B8I1M7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

394503:CCEL RS08775
gene id: 394503:CCEL_RS08775
uniprot id: B8I2U7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

394503:CCEL RS03780
gene id: 394503:CCEL_RS03780
uniprot id: B8I7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

394503:CCEL RS02710
gene id: 394503:CCEL_RS02710
uniprot id: B8I6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

394503:CCEL RS00820
gene id: 394503:CCEL_RS00820
uniprot id: B8I4J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

394503:CCEL RS03085
gene id: 394503:CCEL_RS03085
uniprot id: B8I764
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

394503:CCEL RS07475
gene id: 394503:CCEL_RS07475
uniprot id: B8I209
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

394503:CCEL RS10770
gene id: 394503:CCEL_RS10770
uniprot id: B8I441
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

394503:CCEL RS00280
gene id: 394503:CCEL_RS00280
uniprot id: B8I3W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

394503:CCEL RS08190
gene id: 394503:CCEL_RS08190
uniprot id: B8I2I1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

394503:CCEL RS08365
gene id: 394503:CCEL_RS08365
uniprot id: B8I2L6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS16205
gene id: 394503:CCEL_RS16205
uniprot id: B8I0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

394503:CCEL RS01335
gene id: 394503:CCEL_RS01335
uniprot id: B8I574
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

394503:CCEL RS00090
gene id: 394503:CCEL_RS00090
uniprot id: B8I3S7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

394503:CCEL RS10375
gene id: 394503:CCEL_RS10375
uniprot id: B8I3Q5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

394503:CCEL RS01480
gene id: 394503:CCEL_RS01480
uniprot id: B8I5A3
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS10285
gene id: 394503:CCEL_RS10285
uniprot id: B8I3N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

394503:CCEL RS02945
gene id: 394503:CCEL_RS02945
uniprot id: B8I735
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

394503:CCEL RS01905
gene id: 394503:CCEL_RS01905
uniprot id: B8I5V1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

394503:CCEL RS14805
gene id: 394503:CCEL_RS14805
uniprot id: B8I8D3
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS01720
gene id: 394503:CCEL_RS01720
uniprot id: B8I5R4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS03700
gene id: 394503:CCEL_RS03700
uniprot id: P37698
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 48 (cellulase L) family.
messages: Probable endoglucanase involved in the degradation of cellulose or related beta-glucans.

394503:CCEL RS16900
gene id: 394503:CCEL_RS16900
uniprot id: B8I1M4
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS10130
gene id: 394503:CCEL_RS10130
uniprot id: B8I3K8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

394503:CCEL RS17120
gene id: 394503:CCEL_RS17120
uniprot id: B8I1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS07095
gene id: 394503:CCEL_RS07095
uniprot id: B8I1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS03795
gene id: 394503:CCEL_RS03795
uniprot id: B8I7X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

394503:CCEL RS16260
gene id: 394503:CCEL_RS16260
uniprot id: B8I0X6
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

394503:CCEL RS02820
gene id: 394503:CCEL_RS02820
uniprot id: B8I716
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS05035
gene id: 394503:CCEL_RS05035
uniprot id: B8I9A4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

394503:CCEL RS01550
gene id: 394503:CCEL_RS01550
uniprot id: B8I5N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

394503:CCEL RS10370
gene id: 394503:CCEL_RS10370
uniprot id: B8I3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane

394503:CCEL RS11540
gene id: 394503:CCEL_RS11540
uniprot id: B8I4W7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

394503:CCEL RS04115
gene id: 394503:CCEL_RS04115
uniprot id: B8I8F4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

394503:CCEL RS15135
gene id: 394503:CCEL_RS15135
uniprot id: B8I8W8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

394503:CCEL RS13020
gene id: 394503:CCEL_RS13020
uniprot id: B8I6R0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

394503:CCEL RS15510
gene id: 394503:CCEL_RS15510
uniprot id: B8I051
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

394503:CCEL RS09635
gene id: 394503:CCEL_RS09635
uniprot id: B8I3A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

394503:CCEL RS08720
gene id: 394503:CCEL_RS08720
uniprot id: B8I2T6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

394503:CCEL RS14295
gene id: 394503:CCEL_RS14295
uniprot id: B8I835
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

394503:CCEL RS08925
gene id: 394503:CCEL_RS08925
uniprot id: B8I2X6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

394503:CCEL RS08860
gene id: 394503:CCEL_RS08860
uniprot id: B8I2W4
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

394503:CCEL RS09965
gene id: 394503:CCEL_RS09965
uniprot id: B8I3H4
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

394503:CCEL RS15545
gene id: 394503:CCEL_RS15545
uniprot id: B8I058
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

394503:CCEL RS10350
gene id: 394503:CCEL_RS10350
uniprot id: B8I3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS01020
gene id: 394503:CCEL_RS01020
uniprot id: B8I509
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS02730
gene id: 394503:CCEL_RS02730
uniprot id: B8I6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

394503:CCEL RS18180
gene id: 394503:CCEL_RS18180
uniprot id: B8I8K1
names: Function
messages: Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.

394503:CCEL RS12885
gene id: 394503:CCEL_RS12885
uniprot id: B8I6A9
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

394503:CCEL RS01525
gene id: 394503:CCEL_RS01525
uniprot id: B8I5B2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

394503:CCEL RS05350
gene id: 394503:CCEL_RS05350
uniprot id: B8HZS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS03395
gene id: 394503:CCEL_RS03395
uniprot id: B8I7C3
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

394503:CCEL RS08730
gene id: 394503:CCEL_RS08730
uniprot id: B8I2T8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

394503:CCEL RS06200
gene id: 394503:CCEL_RS06200
uniprot id: B8I0L8
names: Similarity
messages: Belongs to the glycosyl hydrolase 27 family.

394503:CCEL RS12350
gene id: 394503:CCEL_RS12350
uniprot id: B8I602
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

394503:CCEL RS01320
gene id: 394503:CCEL_RS01320
uniprot id: B8I571
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

394503:CCEL RS06370
gene id: 394503:CCEL_RS06370
uniprot id: B8I0Q1
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

394503:CCEL RS14645
gene id: 394503:CCEL_RS14645
uniprot id: B8I8A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

394503:CCEL RS08385
gene id: 394503:CCEL_RS08385
uniprot id: B8I2M0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS10280
gene id: 394503:CCEL_RS10280
uniprot id: B8I3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

394503:CCEL RS14665
gene id: 394503:CCEL_RS14665
uniprot id: B8I8A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

394503:CCEL RS10640
gene id: 394503:CCEL_RS10640
uniprot id: B8I415
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

394503:CCEL RS05775
gene id: 394503:CCEL_RS05775
uniprot id: B8I009
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS09560
gene id: 394503:CCEL_RS09560
uniprot id: B8I393
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

394503:CCEL RS06645
gene id: 394503:CCEL_RS06645
uniprot id: B8I179
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

394503:CCEL RS07965
gene id: 394503:CCEL_RS07965
uniprot id: B8I2C5
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

394503:CCEL RS00505
gene id: 394503:CCEL_RS00505
uniprot id: B8I4D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

394503:CCEL RS02410
gene id: 394503:CCEL_RS02410
uniprot id: B8I6G9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS15395
gene id: 394503:CCEL_RS15395
uniprot id: B8I922
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

394503:CCEL RS12935
gene id: 394503:CCEL_RS12935
uniprot id: B8I6C0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

394503:CCEL RS01935
gene id: 394503:CCEL_RS01935
uniprot id: B8I5V7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

394503:CCEL RS03285
gene id: 394503:CCEL_RS03285
uniprot id: B8I7A3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

394503:CCEL RS05635
gene id: 394503:CCEL_RS05635
uniprot id: B8HZY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS10395
gene id: 394503:CCEL_RS10395
uniprot id: B8I3Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

394503:CCEL RS04290
gene id: 394503:CCEL_RS04290
uniprot id: B8I8I6
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

394503:CCEL RS04025
gene id: 394503:CCEL_RS04025
uniprot id: B8I812
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

394503:CCEL RS02725
gene id: 394503:CCEL_RS02725
uniprot id: B8I6N0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

394503:CCEL RS14130
gene id: 394503:CCEL_RS14130
uniprot id: B8I7N0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

394503:CCEL RS08570
gene id: 394503:CCEL_RS08570
uniprot id: B8I2Q7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

394503:CCEL RS15825
gene id: 394503:CCEL_RS15825
uniprot id: B8I0B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

394503:CCEL RS02940
gene id: 394503:CCEL_RS02940
uniprot id: B8I734
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

394503:CCEL RS05095
gene id: 394503:CCEL_RS05095
uniprot id: B8I9B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS05055
gene id: 394503:CCEL_RS05055
uniprot id: B8I9A8
names: Similarity
messages: Belongs to the FGGY kinase family.

394503:CCEL RS04010
gene id: 394503:CCEL_RS04010
uniprot id: B8I809
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

394503:CCEL RS02660
gene id: 394503:CCEL_RS02660
uniprot id: B8I6L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

394503:CCEL RS12465
gene id: 394503:CCEL_RS12465
uniprot id: B8I625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

394503:CCEL RS04680
gene id: 394503:CCEL_RS04680
uniprot id: B8I8R0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

394503:CCEL RS15140
gene id: 394503:CCEL_RS15140
uniprot id: B8I8W9
names: Similarity
messages: Belongs to the Fur family.

394503:CCEL RS14775
gene id: 394503:CCEL_RS14775
uniprot id: B8I8C7
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS03935
gene id: 394503:CCEL_RS03935
uniprot id: B8I7Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

394503:CCEL RS15980
gene id: 394503:CCEL_RS15980
uniprot id: B8I0F0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

394503:CCEL RS10605
gene id: 394503:CCEL_RS10605
uniprot id: B8I408
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

394503:CCEL RS03620
gene id: 394503:CCEL_RS03620
uniprot id: B8I7T4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

394503:CCEL RS00590
gene id: 394503:CCEL_RS00590
uniprot id: B8I4E8
names: Similarity
messages: Belongs to the GSP E family.

394503:CCEL RS10495
gene id: 394503:CCEL_RS10495
uniprot id: B8I3Y8
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

394503:CCEL RS09025
gene id: 394503:CCEL_RS09025
uniprot id: B8I2Z3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

394503:CCEL RS02440
gene id: 394503:CCEL_RS02440
uniprot id: B8I6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

394503:CCEL RS02530
gene id: 394503:CCEL_RS02530
uniprot id: B8I6J3
names: Similarity
messages: Belongs to the GSP E family.

394503:CCEL RS10430
gene id: 394503:CCEL_RS10430
uniprot id: B8I3X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

394503:CCEL RS13120
gene id: 394503:CCEL_RS13120
uniprot id: B8I6T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

394503:CCEL RS05850
gene id: 394503:CCEL_RS05850
uniprot id: B8I024
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS13815
gene id: 394503:CCEL_RS13815
uniprot id: B8I7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

394503:CCEL RS06755
gene id: 394503:CCEL_RS06755
uniprot id: B8I1A1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS09970
gene id: 394503:CCEL_RS09970
uniprot id: B8I3H5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

394503:CCEL RS13760
gene id: 394503:CCEL_RS13760
uniprot id: B8I7G4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

394503:CCEL RS05360
gene id: 394503:CCEL_RS05360
uniprot id: B8HZS7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

394503:CCEL RS17130
gene id: 394503:CCEL_RS17130
uniprot id: B8I1R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

394503:CCEL RS10760
gene id: 394503:CCEL_RS10760
uniprot id: B8I439
names: Similarity
messages: Belongs to the peptidase C40 family.

394503:CCEL RS10380
gene id: 394503:CCEL_RS10380
uniprot id: B8I3Q6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

394503:CCEL RS04570
gene id: 394503:CCEL_RS04570
uniprot id: B8I8N9
names: Subcellular Location Annotation
messages: Membrane

394503:CCEL RS00860
gene id: 394503:CCEL_RS00860
uniprot id: B8I4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

394503:CCEL RS00760
gene id: 394503:CCEL_RS00760
uniprot id: B8I4I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS05935
gene id: 394503:CCEL_RS05935
uniprot id: B8I041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

394503:CCEL RS12315
gene id: 394503:CCEL_RS12315
uniprot id: B8I5M4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

394503:CCEL RS10930
gene id: 394503:CCEL_RS10930
uniprot id: B8I473
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

394503:CCEL RS05370
gene id: 394503:CCEL_RS05370
uniprot id: B8HZS9
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

394503:CCEL RS01300
gene id: 394503:CCEL_RS01300
uniprot id: B8I567
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

394503:CCEL RS01930
gene id: 394503:CCEL_RS01930
uniprot id: B8I5V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

394503:CCEL RS10095
gene id: 394503:CCEL_RS10095
uniprot id: B8I3K0
names: Similarity
messages: Belongs to the Fur family.

394503:CCEL RS14755
gene id: 394503:CCEL_RS14755
uniprot id: B8I8C3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

394503:CCEL RS07715
gene id: 394503:CCEL_RS07715
uniprot id: B8I255
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

394503:CCEL RS06870
gene id: 394503:CCEL_RS06870
uniprot id: B8I1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

394503:CCEL RS06405
gene id: 394503:CCEL_RS06405
uniprot id: B8I0Q8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

394503:CCEL RS08435
gene id: 394503:CCEL_RS08435
uniprot id: B8I2N0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

394503:CCEL RS16710
gene id: 394503:CCEL_RS16710
uniprot id: B8I165
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

394503:CCEL RS05145
gene id: 394503:CCEL_RS05145
uniprot id: B8I9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

394503:CCEL RS08950
gene id: 394503:CCEL_RS08950
uniprot id: B8I2Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

394503:CCEL RS02560
gene id: 394503:CCEL_RS02560
uniprot id: B8I6K0
names: Similarity
messages: Belongs to the peptidase A24 family.

394503:CCEL RS07145
gene id: 394503:CCEL_RS07145
uniprot id: B8I1H6
names: Subcellular Location Annotation
messages: Cell membrane

394503:CCEL RS17280
gene id: 394503:CCEL_RS17280
uniprot id: B8I1U5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

394503:CCEL RS02900
gene id: 394503:CCEL_RS02900
uniprot id: B8I726
names: Similarity
messages: Belongs to the UPF0749 family.

394503:CCEL RS12860
gene id: 394503:CCEL_RS12860
uniprot id: B8I6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

394503:CCEL RS01605
gene id: 394503:CCEL_RS01605
uniprot id: B8I5P1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

394503:CCEL RS08530
gene id: 394503:CCEL_RS08530
uniprot id: B8I2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

394503:CCEL RS09755
gene id: 394503:CCEL_RS09755
uniprot id: B8I3D2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

394503:CCEL RS04610
gene id: 394503:CCEL_RS04610
uniprot id: B8I8P7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

394503:CCEL RS08850
gene id: 394503:CCEL_RS08850
uniprot id: B8I2W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

394503:CCEL RS10980
gene id: 394503:CCEL_RS10980
uniprot id: B8I482
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

394503:CCEL RS03940
gene id: 394503:CCEL_RS03940
uniprot id: B8I7Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

394503:CCEL RS12855
gene id: 394503:CCEL_RS12855
uniprot id: B8I6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

394503:CCEL RS06350
gene id: 394503:CCEL_RS06350
uniprot id: B8I0P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

394503:CCEL RS15165
gene id: 394503:CCEL_RS15165
uniprot id: B8I8X3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

394503:CCEL RS06185
gene id: 394503:CCEL_RS06185
uniprot id: B8I0L5
names: Subcellular Location Annotation
messages: Secreted

394503:CCEL RS17020
gene id: 394503:CCEL_RS17020
uniprot id: B8I1P7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

394503:CCEL RS02985
gene id: 394503:CCEL_RS02985
uniprot id: B8I744
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

394503:CCEL RS01540
gene id: 394503:CCEL_RS01540
uniprot id: B8I5B5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

394503:CCEL RS17445
gene id: 394503:CCEL_RS17445
uniprot id: B8I2A1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

394503:CCEL RS03470
gene id: 394503:CCEL_RS03470
uniprot id: B8I7Q5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

394503:CCEL RS17510
gene id: 394503:CCEL_RS17510
uniprot id: B8I2A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

394503:CCEL RS13005
gene id: 394503:CCEL_RS13005
uniprot id: B8I6Q7
names: Similarity
messages: Belongs to the citrate synthase family.

394503:CCEL RS17090
gene id: 394503:CCEL_RS17090
uniprot id: B8I1R0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

394503:CCEL RS10615
gene id: 394503:CCEL_RS10615
uniprot id: B8I410
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

394503:CCEL RS01315
gene id: 394503:CCEL_RS01315
uniprot id: B8I570
names: Similarity
messages: Belongs to the MotB family.

394503:CCEL RS05910
gene id: 394503:CCEL_RS05910
uniprot id: B8I036
names: Cofactor
messages: Binds 1 zinc ion per subunit.

394503:CCEL RS12295
gene id: 394503:CCEL_RS12295
uniprot id: B8I5M0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

394503:CCEL RS01745
gene id: 394503:CCEL_RS01745
uniprot id: B8I5R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

394503:CCEL RS17540
gene id: 394503:CCEL_RS17540
uniprot id: B8I2B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

394503:CCEL RS08425
gene id: 394503:CCEL_RS08425
uniprot id: B8I2M8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

394503:CCEL RS03945
gene id: 394503:CCEL_RS03945
uniprot id: B8I7Z6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

394503:CCEL RS17365
gene id: 394503:CCEL_RS17365
uniprot id: B8I285
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

394503:CCEL RS12985
gene id: 394503:CCEL_RS12985
uniprot id: B8I6Q3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.