393595:ABO RS08100
gene id: 393595:ABO_RS08100
uniprot id: Q0VP88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS04420
gene id: 393595:ABO_RS04420
uniprot id: Q0VR94
names: Similarity
messages: Belongs to the cytochrome c-552 family.

393595:ABO RS08445
gene id: 393595:ABO_RS08445
uniprot id: Q0VP20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

393595:ABO RS02400
gene id: 393595:ABO_RS02400
uniprot id: Q0VSD7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

393595:ABO RS10045
gene id: 393595:ABO_RS10045
uniprot id: Q0VN47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

393595:ABO RS11355
gene id: 393595:ABO_RS11355
uniprot id: Q0VMD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

393595:ABO RS13245
gene id: 393595:ABO_RS13245
uniprot id: Q0VLA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

393595:ABO RS10985
gene id: 393595:ABO_RS10985
uniprot id: Q0VML2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

393595:ABO RS11810
gene id: 393595:ABO_RS11810
uniprot id: Q0VM49
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

393595:ABO RS05345
gene id: 393595:ABO_RS05345
uniprot id: Q0VQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

393595:ABO RS01995
gene id: 393595:ABO_RS01995
uniprot id: Q0VSL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

393595:ABO RS12435
gene id: 393595:ABO_RS12435
uniprot id: Q0VLS0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

393595:ABO RS11005
gene id: 393595:ABO_RS11005
uniprot id: Q0VMK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

393595:ABO RS13360
gene id: 393595:ABO_RS13360
uniprot id: Q0VL85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

393595:ABO RS08990
gene id: 393595:ABO_RS08990
uniprot id: Q0VNQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

393595:ABO RS05990
gene id: 393595:ABO_RS05990
uniprot id: Q0VQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

393595:ABO RS08465
gene id: 393595:ABO_RS08465
uniprot id: Q0VP16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

393595:ABO RS13160
gene id: 393595:ABO_RS13160
uniprot id: Q0VLC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

393595:ABO RS02455
gene id: 393595:ABO_RS02455
uniprot id: Q0VSC6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS05635
gene id: 393595:ABO_RS05635
uniprot id: Q0VQK9
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS07415
gene id: 393595:ABO_RS07415
uniprot id: Q0VPL9
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

393595:ABO RS01570
gene id: 393595:ABO_RS01570
uniprot id: Q0VSU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS10740
gene id: 393595:ABO_RS10740
uniprot id: Q0VMR1
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

393595:ABO RS10810
gene id: 393595:ABO_RS10810
uniprot id: Q0VMP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

393595:ABO RS13910
gene id: 393595:ABO_RS13910
uniprot id: Q0VKX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

393595:ABO RS12160
gene id: 393595:ABO_RS12160
uniprot id: Q0VLX6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

393595:ABO RS04685
gene id: 393595:ABO_RS04685
uniprot id: Q0VR43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS11210
gene id: 393595:ABO_RS11210
uniprot id: Q0VMG7
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

393595:ABO RS00675
gene id: 393595:ABO_RS00675
uniprot id: Q0VTD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

393595:ABO RS11350
gene id: 393595:ABO_RS11350
uniprot id: Q0VME0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

393595:ABO RS12515
gene id: 393595:ABO_RS12515
uniprot id: Q0VLQ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

393595:ABO RS07650
gene id: 393595:ABO_RS07650
uniprot id: Q0VPH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

393595:ABO RS02705
gene id: 393595:ABO_RS02705
uniprot id: Q0VS80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

393595:ABO RS11510
gene id: 393595:ABO_RS11510
uniprot id: Q0VMA8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS11055
gene id: 393595:ABO_RS11055
uniprot id: Q0VMJ8
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

393595:ABO RS13350
gene id: 393595:ABO_RS13350
uniprot id: Q0VL87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS01495
gene id: 393595:ABO_RS01495
uniprot id: Q0VSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

393595:ABO RS09485
gene id: 393595:ABO_RS09485
uniprot id: Q0VNF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

393595:ABO RS11740
gene id: 393595:ABO_RS11740
uniprot id: Q0VM62
names: Similarity
messages: Belongs to the cytochrome P450 family.

393595:ABO RS02600
gene id: 393595:ABO_RS02600
uniprot id: Q0VSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

393595:ABO RS10395
gene id: 393595:ABO_RS10395
uniprot id: Q0VMX9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

393595:ABO RS09130
gene id: 393595:ABO_RS09130
uniprot id: Q0VNN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

393595:ABO RS12240
gene id: 393595:ABO_RS12240
uniprot id: Q0VLW0
names: Similarity
messages: Belongs to the UPF0047 family.

393595:ABO RS01695
gene id: 393595:ABO_RS01695
uniprot id: Q0VSR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

393595:ABO RS04330
gene id: 393595:ABO_RS04330
uniprot id: Q0VRB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS06975
gene id: 393595:ABO_RS06975
uniprot id: Q0VPV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

393595:ABO RS10390
gene id: 393595:ABO_RS10390
uniprot id: Q0VMY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

393595:ABO RS06800
gene id: 393595:ABO_RS06800
uniprot id: Q0VPY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

393595:ABO RS07595
gene id: 393595:ABO_RS07595
uniprot id: Q0VPI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS06535
gene id: 393595:ABO_RS06535
uniprot id: Q0VQ36
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS13955
gene id: 393595:ABO_RS13955
uniprot id: Q0VKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

393595:ABO RS02060
gene id: 393595:ABO_RS02060
uniprot id: Q0VSK5
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

393595:ABO RS11390
gene id: 393595:ABO_RS11390
uniprot id: Q0VMD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

393595:ABO RS00845
gene id: 393595:ABO_RS00845
uniprot id: Q0VTA4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

393595:ABO RS00650
gene id: 393595:ABO_RS00650
uniprot id: Q0VTE2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

393595:ABO RS11155
gene id: 393595:ABO_RS11155
uniprot id: Q0VMH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

393595:ABO RS09265
gene id: 393595:ABO_RS09265
uniprot id: Q0VNK3
names: Similarity
messages: Belongs to the aspartokinase family.

393595:ABO RS06675
gene id: 393595:ABO_RS06675
uniprot id: Q0VQ08
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

393595:ABO RS07565
gene id: 393595:ABO_RS07565
uniprot id: Q0VPJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

393595:ABO RS03255
gene id: 393595:ABO_RS03255
uniprot id: Q0VRX0
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS05925
gene id: 393595:ABO_RS05925
uniprot id: Q0VQF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

393595:ABO RS14405
gene id: 393595:ABO_RS14405
uniprot id: Q0VN88
names: Subcellular Location Annotation
messages: Cytoplasm

393595:ABO RS13715
gene id: 393595:ABO_RS13715
uniprot id: Q0VL16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

393595:ABO RS01990
gene id: 393595:ABO_RS01990
uniprot id: Q0VSL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

393595:ABO RS04350
gene id: 393595:ABO_RS04350
uniprot id: Q0VRA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

393595:ABO RS00170
gene id: 393595:ABO_RS00170
uniprot id: Q0VTM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

393595:ABO RS10960
gene id: 393595:ABO_RS10960
uniprot id: Q0VML6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS09465
gene id: 393595:ABO_RS09465
uniprot id: Q0VNG3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

393595:ABO RS01595
gene id: 393595:ABO_RS01595
uniprot id: Q0VST6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

393595:ABO RS11305
gene id: 393595:ABO_RS11305
uniprot id: Q0VME9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

393595:ABO RS11250
gene id: 393595:ABO_RS11250
uniprot id: Q0VMF9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

393595:ABO RS00245
gene id: 393595:ABO_RS00245
uniprot id: Q0VTG6
names: Similarity
messages: Belongs to the UPF0234 family.

393595:ABO RS08345
gene id: 393595:ABO_RS08345
uniprot id: Q0VP40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

393595:ABO RS09815
gene id: 393595:ABO_RS09815
uniprot id: Q0VN94
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

393595:ABO RS00665
gene id: 393595:ABO_RS00665
uniprot id: Q0VTD9
names: Similarity
messages: Belongs to the DprA/Smf family.

393595:ABO RS02740
gene id: 393595:ABO_RS02740
uniprot id: Q0VS73
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

393595:ABO RS04135
gene id: 393595:ABO_RS04135
uniprot id: Q0VRE9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

393595:ABO RS02910
gene id: 393595:ABO_RS02910
uniprot id: Q0VS39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

393595:ABO RS11290
gene id: 393595:ABO_RS11290
uniprot id: Q0VMF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

393595:ABO RS02915
gene id: 393595:ABO_RS02915
uniprot id: Q0VS38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

393595:ABO RS09250
gene id: 393595:ABO_RS09250
uniprot id: Q0VNK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

393595:ABO RS03690
gene id: 393595:ABO_RS03690
uniprot id: Q0VRN6
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

393595:ABO RS01210
gene id: 393595:ABO_RS01210
uniprot id: Q0VT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

393595:ABO RS12225
gene id: 393595:ABO_RS12225
uniprot id: Q0VLW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

393595:ABO RS11145
gene id: 393595:ABO_RS11145
uniprot id: Q0VMI0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

393595:ABO RS09980
gene id: 393595:ABO_RS09980
uniprot id: Q0VN60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS04235
gene id: 393595:ABO_RS04235
uniprot id: Q0VRC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

393595:ABO RS03635
gene id: 393595:ABO_RS03635
uniprot id: Q0VRP7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

393595:ABO RS02075
gene id: 393595:ABO_RS02075
uniprot id: Q0VSK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

393595:ABO RS00835
gene id: 393595:ABO_RS00835
uniprot id: Q0VTA6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

393595:ABO RS11460
gene id: 393595:ABO_RS11460
uniprot id: Q0VMB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

393595:ABO RS02490
gene id: 393595:ABO_RS02490
uniprot id: Q0VSB9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

393595:ABO RS12800
gene id: 393595:ABO_RS12800
uniprot id: Q0VLJ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS12695
gene id: 393595:ABO_RS12695
uniprot id: Q0VLL7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

393595:ABO RS10040
gene id: 393595:ABO_RS10040
uniprot id: Q0VN48
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

393595:ABO RS10670
gene id: 393595:ABO_RS10670
uniprot id: Q0VMS5
names: Similarity
messages: Belongs to the ParB family.

393595:ABO RS13480
gene id: 393595:ABO_RS13480
uniprot id: Q0VL62
names: Similarity
messages: Belongs to the glutathione peroxidase family.

393595:ABO RS10835
gene id: 393595:ABO_RS10835
uniprot id: Q0VMP1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS04715
gene id: 393595:ABO_RS04715
uniprot id: Q0VR37
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

393595:ABO RS06485
gene id: 393595:ABO_RS06485
uniprot id: Q0VQ46
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

393595:ABO RS05430
gene id: 393595:ABO_RS05430
uniprot id: Q0VQQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

393595:ABO RS12120
gene id: 393595:ABO_RS12120
uniprot id: Q0VLY5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

393595:ABO RS12015
gene id: 393595:ABO_RS12015
uniprot id: Q0VM06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS10335
gene id: 393595:ABO_RS10335
uniprot id: Q0VMZ1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

393595:ABO RS09140
gene id: 393595:ABO_RS09140
uniprot id: Q0VNM8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS11315
gene id: 393595:ABO_RS11315
uniprot id: Q0VME7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

393595:ABO RS07025
gene id: 393595:ABO_RS07025
uniprot id: Q0VPU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

393595:ABO RS05455
gene id: 393595:ABO_RS05455
uniprot id: Q0VQP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

393595:ABO RS06960
gene id: 393595:ABO_RS06960
uniprot id: Q0VPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

393595:ABO RS04825
gene id: 393595:ABO_RS04825
uniprot id: Q0VR16
names: Similarity
messages: Belongs to the UDPGP type 2 family.

393595:ABO RS07600
gene id: 393595:ABO_RS07600
uniprot id: Q0VPI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS01085
gene id: 393595:ABO_RS01085
uniprot id: Q0VT56
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

393595:ABO RS07120
gene id: 393595:ABO_RS07120
uniprot id: Q0VPS6
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS08555
gene id: 393595:ABO_RS08555
uniprot id: Q0VNZ8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

393595:ABO RS02085
gene id: 393595:ABO_RS02085
uniprot id: Q0VSK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

393595:ABO RS11660
gene id: 393595:ABO_RS11660
uniprot id: Q0VM78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

393595:ABO RS07575
gene id: 393595:ABO_RS07575
uniprot id: Q0VPI8
names: Similarity
messages: Belongs to the TrpF family.

393595:ABO RS01955
gene id: 393595:ABO_RS01955
uniprot id: Q0VSM6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

393595:ABO RS03725
gene id: 393595:ABO_RS03725
uniprot id: Q0VRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

393595:ABO RS01070
gene id: 393595:ABO_RS01070
uniprot id: Q0VT59
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS09160
gene id: 393595:ABO_RS09160
uniprot id: Q0VNM4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

393595:ABO RS10540
gene id: 393595:ABO_RS10540
uniprot id: Q0VMV0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

393595:ABO RS10605
gene id: 393595:ABO_RS10605
uniprot id: Q0VMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

393595:ABO RS09460
gene id: 393595:ABO_RS09460
uniprot id: Q0VNG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

393595:ABO RS13380
gene id: 393595:ABO_RS13380
uniprot id: Q0VL81
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

393595:ABO RS02065
gene id: 393595:ABO_RS02065
uniprot id: Q0VSK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

393595:ABO RS07560
gene id: 393595:ABO_RS07560
uniprot id: Q0VPJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

393595:ABO RS10415
gene id: 393595:ABO_RS10415
uniprot id: Q0VMX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

393595:ABO RS10475
gene id: 393595:ABO_RS10475
uniprot id: Q0VMW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Membrane

393595:ABO RS12375
gene id: 393595:ABO_RS12375
uniprot id: Q0VLT1
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

393595:ABO RS10140
gene id: 393595:ABO_RS10140
uniprot id: Q0VN28
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS10245
gene id: 393595:ABO_RS10245
uniprot id: Q0VN10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

393595:ABO RS05475
gene id: 393595:ABO_RS05475
uniprot id: Q0VQP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

393595:ABO RS05985
gene id: 393595:ABO_RS05985
uniprot id: Q0VQE2
names: Subcellular Location Annotation
messages: Cytoplasm

393595:ABO RS03090
gene id: 393595:ABO_RS03090
uniprot id: Q0VS02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

393595:ABO RS11940
gene id: 393595:ABO_RS11940
uniprot id: Q0VM22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

393595:ABO RS07775
gene id: 393595:ABO_RS07775
uniprot id: Q0VPF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

393595:ABO RS12670
gene id: 393595:ABO_RS12670
uniprot id: Q0VLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

393595:ABO RS12280
gene id: 393595:ABO_RS12280
uniprot id: Q0VLV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

393595:ABO RS07840
gene id: 393595:ABO_RS07840
uniprot id: Q0VPD9
names: Similarity
messages: Belongs to the universal stress protein A family.

393595:ABO RS05360
gene id: 393595:ABO_RS05360
uniprot id: Q0VQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

393595:ABO RS03545
gene id: 393595:ABO_RS03545
uniprot id: Q0VRR4
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS14070
gene id: 393595:ABO_RS14070
uniprot id: Q0VKU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

393595:ABO RS13430
gene id: 393595:ABO_RS13430
uniprot id: Q0VL72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

393595:ABO RS12060
gene id: 393595:ABO_RS12060
uniprot id: Q0VLZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

393595:ABO RS02470
gene id: 393595:ABO_RS02470
uniprot id: Q0VSC3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

393595:ABO RS14040
gene id: 393595:ABO_RS14040
uniprot id: Q0VKV3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

393595:ABO RS05530
gene id: 393595:ABO_RS05530
uniprot id: Q0VQN0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

393595:ABO RS06655
gene id: 393595:ABO_RS06655
uniprot id: Q0VQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

393595:ABO RS08005
gene id: 393595:ABO_RS08005
uniprot id: Q0VPA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane

393595:ABO RS09615
gene id: 393595:ABO_RS09615
uniprot id: Q0VND2
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

393595:ABO RS08440
gene id: 393595:ABO_RS08440
uniprot id: Q0VP21
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

393595:ABO RS00905
gene id: 393595:ABO_RS00905
uniprot id: Q0VT92
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS01005
gene id: 393595:ABO_RS01005
uniprot id: Q5CA10
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

393595:ABO RS04140
gene id: 393595:ABO_RS04140
uniprot id: Q0VRE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

393595:ABO RS07570
gene id: 393595:ABO_RS07570
uniprot id: Q0VPI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

393595:ABO RS11150
gene id: 393595:ABO_RS11150
uniprot id: Q0VMH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

393595:ABO RS02140
gene id: 393595:ABO_RS02140
uniprot id: Q0VSI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

393595:ABO RS01720
gene id: 393595:ABO_RS01720
uniprot id: Q0VSR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

393595:ABO RS04900
gene id: 393595:ABO_RS04900
uniprot id: Q0VR03
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

393595:ABO RS03745
gene id: 393595:ABO_RS03745
uniprot id: Q0VRM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

393595:ABO RS09665
gene id: 393595:ABO_RS09665
uniprot id: Q0VNC3
names: Similarity
messages: Belongs to the HAM1 NTPase family.

393595:ABO RS03110
gene id: 393595:ABO_RS03110
uniprot id: Q0VRZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

393595:ABO RS02175
gene id: 393595:ABO_RS02175
uniprot id: Q0VSI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

393595:ABO RS02395
gene id: 393595:ABO_RS02395
uniprot id: Q0VSD8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

393595:ABO RS08490
gene id: 393595:ABO_RS08490
uniprot id: Q0VP11
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

393595:ABO RS11690
gene id: 393595:ABO_RS11690
uniprot id: Q0VM72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

393595:ABO RS03795
gene id: 393595:ABO_RS03795
uniprot id: Q0VRL5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

393595:ABO RS05525
gene id: 393595:ABO_RS05525
uniprot id: Q0VQN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

393595:ABO RS00860
gene id: 393595:ABO_RS00860
uniprot id: Q0VTA1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

393595:ABO RS11785
gene id: 393595:ABO_RS11785
uniprot id: Q0VM54
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

393595:ABO RS07965
gene id: 393595:ABO_RS07965
uniprot id: Q0VPB5
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS01550
gene id: 393595:ABO_RS01550
uniprot id: Q0VSU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

393595:ABO RS09165
gene id: 393595:ABO_RS09165
uniprot id: Q0VNM3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

393595:ABO RS10730
gene id: 393595:ABO_RS10730
uniprot id: Q0VMR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

393595:ABO RS11230
gene id: 393595:ABO_RS11230
uniprot id: Q0VMG3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

393595:ABO RS12235
gene id: 393595:ABO_RS12235
uniprot id: Q0VLW1
names: Similarity
messages: Belongs to the UPF0319 family.

393595:ABO RS00745
gene id: 393595:ABO_RS00745
uniprot id: Q0VTC4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

393595:ABO RS12775
gene id: 393595:ABO_RS12775
uniprot id: Q0VLK0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

393595:ABO RS09605
gene id: 393595:ABO_RS09605
uniprot id: Q0VND4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

393595:ABO RS06415
gene id: 393595:ABO_RS06415
uniprot id: Q0VQ60
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS01580
gene id: 393595:ABO_RS01580
uniprot id: Q0VST9
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS12205
gene id: 393595:ABO_RS12205
uniprot id: Q0VLW7
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

393595:ABO RS09420
gene id: 393595:ABO_RS09420
uniprot id: Q0VNH1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

393595:ABO RS06595
gene id: 393595:ABO_RS06595
uniprot id: Q0VQ24
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

393595:ABO RS08340
gene id: 393595:ABO_RS08340
uniprot id: Q0VP41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

393595:ABO RS04105
gene id: 393595:ABO_RS04105
uniprot id: Q0VRF5
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS00610
gene id: 393595:ABO_RS00610
uniprot id: Q0VTH3
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Binds 2 Fe(3+) ions per subunit.
messages: Catalyzes the hydroxylation of n-alkanes in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C8-C16 hydrocarbons.
messages: Cell inner membrane
messages: Induced by n-alkanes.

393595:ABO RS13965
gene id: 393595:ABO_RS13965
uniprot id: Q0VKW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

393595:ABO RS01315
gene id: 393595:ABO_RS01315
uniprot id: Q0VSZ1
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

393595:ABO RS03980
gene id: 393595:ABO_RS03980
uniprot id: Q0VRH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

393595:ABO RS13985
gene id: 393595:ABO_RS13985
uniprot id: Q0VKW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

393595:ABO RS03760
gene id: 393595:ABO_RS03760
uniprot id: Q0VRM2
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

393595:ABO RS01655
gene id: 393595:ABO_RS01655
uniprot id: Q0VSS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

393595:ABO RS02735
gene id: 393595:ABO_RS02735
uniprot id: Q0VS74
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

393595:ABO RS02215
gene id: 393595:ABO_RS02215
uniprot id: Q0VSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

393595:ABO RS10965
gene id: 393595:ABO_RS10965
uniprot id: Q0VML5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS01970
gene id: 393595:ABO_RS01970
uniprot id: Q0VSM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

393595:ABO RS06545
gene id: 393595:ABO_RS06545
uniprot id: Q0VQ34
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

393595:ABO RS06870
gene id: 393595:ABO_RS06870
uniprot id: Q0VPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

393595:ABO RS13445
gene id: 393595:ABO_RS13445
uniprot id: Q0VL69
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

393595:ABO RS03605
gene id: 393595:ABO_RS03605
uniprot id: Q0VRQ3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

393595:ABO RS05350
gene id: 393595:ABO_RS05350
uniprot id: Q0VQR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

393595:ABO RS10105
gene id: 393595:ABO_RS10105
uniprot id: Q0VN35
names: Similarity
messages: Belongs to the peptidase S13 family.

393595:ABO RS11345
gene id: 393595:ABO_RS11345
uniprot id: Q0VME1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

393595:ABO RS09630
gene id: 393595:ABO_RS09630
uniprot id: Q0VNC9
names: Similarity
messages: Belongs to the SufE family.

393595:ABO RS08025
gene id: 393595:ABO_RS08025
uniprot id: Q0VPA3
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS05960
gene id: 393595:ABO_RS05960
uniprot id: Q0VQE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

393595:ABO RS02835
gene id: 393595:ABO_RS02835
uniprot id: Q0VS54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

393595:ABO RS05805
gene id: 393595:ABO_RS05805
uniprot id: Q0VQH7
names: Similarity
messages: Belongs to the P(II) protein family.

393595:ABO RS12390
gene id: 393595:ABO_RS12390
uniprot id: Q0VLS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS11190
gene id: 393595:ABO_RS11190
uniprot id: Q0VMH1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

393595:ABO RS07500
gene id: 393595:ABO_RS07500
uniprot id: Q0VPK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

393595:ABO RS01905
gene id: 393595:ABO_RS01905
uniprot id: Q0VSN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS13575
gene id: 393595:ABO_RS13575
uniprot id: Q0VL44
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS02845
gene id: 393595:ABO_RS02845
uniprot id: Q0VS52
names: Subcellular Location Annotation
messages: Cytoplasm

393595:ABO RS11520
gene id: 393595:ABO_RS11520
uniprot id: Q0VMA6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

393595:ABO RS05880
gene id: 393595:ABO_RS05880
uniprot id: Q0VQG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

393595:ABO RS12190
gene id: 393595:ABO_RS12190
uniprot id: Q0VLX0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

393595:ABO RS12540
gene id: 393595:ABO_RS12540
uniprot id: Q0VLP8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

393595:ABO RS00400
gene id: 393595:ABO_RS00400
uniprot id: Q0VKT3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

393595:ABO RS03875
gene id: 393595:ABO_RS03875
uniprot id: Q0VRJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

393595:ABO RS03070
gene id: 393595:ABO_RS03070
uniprot id: Q0VS06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS08415
gene id: 393595:ABO_RS08415
uniprot id: Q0VP26
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

393595:ABO RS03080
gene id: 393595:ABO_RS03080
uniprot id: Q0VS04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

393595:ABO RS04725
gene id: 393595:ABO_RS04725
uniprot id: Q0VR35
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS02370
gene id: 393595:ABO_RS02370
uniprot id: Q0VSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

393595:ABO RS02225
gene id: 393595:ABO_RS02225
uniprot id: Q0VSH1
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS13145
gene id: 393595:ABO_RS13145
uniprot id: Q0VLC7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

393595:ABO RS04890
gene id: 393595:ABO_RS04890
uniprot id: Q0VR05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

393595:ABO RS08910
gene id: 393595:ABO_RS08910
uniprot id: Q0VNS6
names: Similarity
messages: Belongs to the PhzF family.

393595:ABO RS11070
gene id: 393595:ABO_RS11070
uniprot id: Q0VMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

393595:ABO RS07035
gene id: 393595:ABO_RS07035
uniprot id: Q0VPU2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

393595:ABO RS04720
gene id: 393595:ABO_RS04720
uniprot id: Q0VR36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

393595:ABO RS01455
gene id: 393595:ABO_RS01455
uniprot id: Q0VSW4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS13900
gene id: 393595:ABO_RS13900
uniprot id: Q0VKY1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

393595:ABO RS06550
gene id: 393595:ABO_RS06550
uniprot id: Q0VQ33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

393595:ABO RS08230
gene id: 393595:ABO_RS08230
uniprot id: Q0VP64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

393595:ABO RS04830
gene id: 393595:ABO_RS04830
uniprot id: Q0VR15
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

393595:ABO RS06835
gene id: 393595:ABO_RS06835
uniprot id: Q0VPY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

393595:ABO RS03730
gene id: 393595:ABO_RS03730
uniprot id: Q0VRM8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

393595:ABO RS06275
gene id: 393595:ABO_RS06275
uniprot id: Q0VQ87
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

393595:ABO RS12455
gene id: 393595:ABO_RS12455
uniprot id: Q0VLR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

393595:ABO RS03535
gene id: 393595:ABO_RS03535
uniprot id: Q0VRR6
names: Similarity
messages: Belongs to the elongation factor P family.

393595:ABO RS06925
gene id: 393595:ABO_RS06925
uniprot id: Q0VPW2
names: Similarity
messages: Belongs to the UPF0246 family.

393595:ABO RS13300
gene id: 393595:ABO_RS13300
uniprot id: Q0VL97
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

393595:ABO RS05460
gene id: 393595:ABO_RS05460
uniprot id: Q0VQP4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

393595:ABO RS00145
gene id: 393595:ABO_RS00145
uniprot id: Q0VTN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS02185
gene id: 393595:ABO_RS02185
uniprot id: Q0VSH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

393595:ABO RS07555
gene id: 393595:ABO_RS07555
uniprot id: Q0VPJ2
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

393595:ABO RS10085
gene id: 393595:ABO_RS10085
uniprot id: Q0VN39
names: Similarity
messages: Belongs to the UPF0250 family.

393595:ABO RS11435
gene id: 393595:ABO_RS11435
uniprot id: Q0VMC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS03860
gene id: 393595:ABO_RS03860
uniprot id: Q0VRK2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

393595:ABO RS02750
gene id: 393595:ABO_RS02750
uniprot id: Q0VS71
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

393595:ABO RS09955
gene id: 393595:ABO_RS09955
uniprot id: Q0VN65
names: Similarity
messages: Belongs to the PhoH family.

393595:ABO RS02505
gene id: 393595:ABO_RS02505
uniprot id: Q0VSB6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS06710
gene id: 393595:ABO_RS06710
uniprot id: Q0VQ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

393595:ABO RS01950
gene id: 393595:ABO_RS01950
uniprot id: Q0VSM7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

393595:ABO RS06145
gene id: 393595:ABO_RS06145
uniprot id: Q0VQA9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

393595:ABO RS11120
gene id: 393595:ABO_RS11120
uniprot id: Q0VMI5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

393595:ABO RS01590
gene id: 393595:ABO_RS01590
uniprot id: Q0VST7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

393595:ABO RS04545
gene id: 393595:ABO_RS04545
uniprot id: Q0VR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS01615
gene id: 393595:ABO_RS01615
uniprot id: Q0VST2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS13825
gene id: 393595:ABO_RS13825
uniprot id: Q0VKZ5
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS04700
gene id: 393595:ABO_RS04700
uniprot id: Q0VR40
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

393595:ABO RS06015
gene id: 393595:ABO_RS06015
uniprot id: Q0VQD6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

393595:ABO RS02460
gene id: 393595:ABO_RS02460
uniprot id: Q0VSC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

393595:ABO RS03105
gene id: 393595:ABO_RS03105
uniprot id: Q0VRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

393595:ABO RS08765
gene id: 393595:ABO_RS08765
uniprot id: Q0VNV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

393595:ABO RS02090
gene id: 393595:ABO_RS02090
uniprot id: Q0VSJ9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

393595:ABO RS01865
gene id: 393595:ABO_RS01865
uniprot id: Q0VSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS12925
gene id: 393595:ABO_RS12925
uniprot id: Q0VLH0
names: Similarity
messages: Belongs to the P(II) protein family.

393595:ABO RS07810
gene id: 393595:ABO_RS07810
uniprot id: Q0VPE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

393595:ABO RS00815
gene id: 393595:ABO_RS00815
uniprot id: Q0VTB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

393595:ABO RS06005
gene id: 393595:ABO_RS06005
uniprot id: Q0VQD8
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

393595:ABO RS03270
gene id: 393595:ABO_RS03270
uniprot id: Q0VRW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

393595:ABO RS10115
gene id: 393595:ABO_RS10115
uniprot id: Q0VN33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

393595:ABO RS09950
gene id: 393595:ABO_RS09950
uniprot id: Q0VN66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS13700
gene id: 393595:ABO_RS13700
uniprot id: Q0VL19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

393595:ABO RS09035
gene id: 393595:ABO_RS09035
uniprot id: Q0VNQ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS01960
gene id: 393595:ABO_RS01960
uniprot id: Q0VSM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

393595:ABO RS10715
gene id: 393595:ABO_RS10715
uniprot id: Q0VMR6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

393595:ABO RS09285
gene id: 393595:ABO_RS09285
uniprot id: Q0VNJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

393595:ABO RS03750
gene id: 393595:ABO_RS03750
uniprot id: Q0VRM4
names: Similarity
messages: Belongs to the glyoxalase I family.

393595:ABO RS11380
gene id: 393595:ABO_RS11380
uniprot id: Q0VMD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS03735
gene id: 393595:ABO_RS03735
uniprot id: Q0VRM7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

393595:ABO RS01265
gene id: 393595:ABO_RS01265
uniprot id: Q0VT01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
messages: Cell inner membrane
messages: Homodimer. Part of the tripartite efflux system MacAB-TolC, which is composed of an inner membrane transporter, MacB, a periplasmic membrane fusion protein, MacA, and an outer membrane component, TolC. The complex forms a large protein conduit and can translocate molecules across both the inner and outer membranes. Interacts with MacA.
messages: Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

393595:ABO RS07170
gene id: 393595:ABO_RS07170
uniprot id: Q0VPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

393595:ABO RS03235
gene id: 393595:ABO_RS03235
uniprot id: Q0VRX3
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

393595:ABO RS01650
gene id: 393595:ABO_RS01650
uniprot id: Q0VSS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

393595:ABO RS10355
gene id: 393595:ABO_RS10355
uniprot id: Q0VMY7
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

393595:ABO RS02980
gene id: 393595:ABO_RS02980
uniprot id: Q0VS24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

393595:ABO RS06875
gene id: 393595:ABO_RS06875
uniprot id: Q0VPX2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

393595:ABO RS11695
gene id: 393595:ABO_RS11695
uniprot id: Q0VM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

393595:ABO RS12965
gene id: 393595:ABO_RS12965
uniprot id: Q0VLG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

393595:ABO RS10685
gene id: 393595:ABO_RS10685
uniprot id: Q0VMS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

393595:ABO RS05975
gene id: 393595:ABO_RS05975
uniprot id: Q0VQE4
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

393595:ABO RS13370
gene id: 393595:ABO_RS13370
uniprot id: Q0VL83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

393595:ABO RS09280
gene id: 393595:ABO_RS09280
uniprot id: Q0VNK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

393595:ABO RS11615
gene id: 393595:ABO_RS11615
uniprot id: Q0VM87
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

393595:ABO RS04165
gene id: 393595:ABO_RS04165
uniprot id: Q0VRE3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

393595:ABO RS05910
gene id: 393595:ABO_RS05910
uniprot id: Q0VQF7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

393595:ABO RS07425
gene id: 393595:ABO_RS07425
uniprot id: Q0VPL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

393595:ABO RS13315
gene id: 393595:ABO_RS13315
uniprot id: Q0VL94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

393595:ABO RS09245
gene id: 393595:ABO_RS09245
uniprot id: Q0VNK7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

393595:ABO RS04430
gene id: 393595:ABO_RS04430
uniprot id: Q0VR92
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS06065
gene id: 393595:ABO_RS06065
uniprot id: Q0VQC6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

393595:ABO RS02955
gene id: 393595:ABO_RS02955
uniprot id: Q0VS30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

393595:ABO RS03240
gene id: 393595:ABO_RS03240
uniprot id: Q0VRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

393595:ABO RS08815
gene id: 393595:ABO_RS08815
uniprot id: Q0VNU5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

393595:ABO RS02125
gene id: 393595:ABO_RS02125
uniprot id: Q0VSJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

393595:ABO RS10690
gene id: 393595:ABO_RS10690
uniprot id: Q0VMS1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

393595:ABO RS12035
gene id: 393595:ABO_RS12035
uniprot id: Q0VM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

393595:ABO RS05870
gene id: 393595:ABO_RS05870
uniprot id: Q0VQG4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

393595:ABO RS10210
gene id: 393595:ABO_RS10210
uniprot id: Q0VN17
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

393595:ABO RS08850
gene id: 393595:ABO_RS08850
uniprot id: Q0VNT8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

393595:ABO RS02810
gene id: 393595:ABO_RS02810
uniprot id: Q0VS59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

393595:ABO RS11555
gene id: 393595:ABO_RS11555
uniprot id: Q0VMA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

393595:ABO RS04690
gene id: 393595:ABO_RS04690
uniprot id: Q0VR42
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

393595:ABO RS02040
gene id: 393595:ABO_RS02040
uniprot id: Q0VSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

393595:ABO RS04805
gene id: 393595:ABO_RS04805
uniprot id: Q0VR20
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

393595:ABO RS09145
gene id: 393595:ABO_RS09145
uniprot id: Q0VNM7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

393595:ABO RS02105
gene id: 393595:ABO_RS02105
uniprot id: Q0VSJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

393595:ABO RS11595
gene id: 393595:ABO_RS11595
uniprot id: Q0VM91
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

393595:ABO RS07545
gene id: 393595:ABO_RS07545
uniprot id: Q0VPJ4
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS00840
gene id: 393595:ABO_RS00840
uniprot id: Q0VTA5
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

393595:ABO RS08360
gene id: 393595:ABO_RS08360
uniprot id: Q0VP37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

393595:ABO RS01705
gene id: 393595:ABO_RS01705
uniprot id: Q0VSR6
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

393595:ABO RS01745
gene id: 393595:ABO_RS01745
uniprot id: Q0VSQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

393595:ABO RS00485
gene id: 393595:ABO_RS00485
uniprot id: Q0VTJ8
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS01015
gene id: 393595:ABO_RS01015
uniprot id: Q5CA09
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

393595:ABO RS05515
gene id: 393595:ABO_RS05515
uniprot id: Q0VQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

393595:ABO RS05295
gene id: 393595:ABO_RS05295
uniprot id: Q0VQS7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

393595:ABO RS11525
gene id: 393595:ABO_RS11525
uniprot id: Q0VMA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

393595:ABO RS00365
gene id: 393595:ABO_RS00365
uniprot id: Q0VKU1
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

393595:ABO RS05040
gene id: 393595:ABO_RS05040
uniprot id: Q0VQX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

393595:ABO RS05505
gene id: 393595:ABO_RS05505
uniprot id: Q0VQN5
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

393595:ABO RS09300
gene id: 393595:ABO_RS09300
uniprot id: Q0VNJ6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

393595:ABO RS09770
gene id: 393595:ABO_RS09770
uniprot id: Q0VNA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

393595:ABO RS04985
gene id: 393595:ABO_RS04985
uniprot id: Q0VQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS02715
gene id: 393595:ABO_RS02715
uniprot id: Q0VS78
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

393595:ABO RS12495
gene id: 393595:ABO_RS12495
uniprot id: Q0VLQ8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

393595:ABO RS14200
gene id: 393595:ABO_RS14200
uniprot id: Q0VSI2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

393595:ABO RS03815
gene id: 393595:ABO_RS03815
uniprot id: Q0VRL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS02135
gene id: 393595:ABO_RS02135
uniprot id: Q0VSJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

393595:ABO RS04550
gene id: 393595:ABO_RS04550
uniprot id: Q0VR70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS03135
gene id: 393595:ABO_RS03135
uniprot id: Q0VRZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

393595:ABO RS01065
gene id: 393595:ABO_RS01065
uniprot id: Q0VT60
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

393595:ABO RS11300
gene id: 393595:ABO_RS11300
uniprot id: Q0VMF0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

393595:ABO RS07615
gene id: 393595:ABO_RS07615
uniprot id: Q0VPI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

393595:ABO RS06830
gene id: 393595:ABO_RS06830
uniprot id: Q0VPY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

393595:ABO RS02760
gene id: 393595:ABO_RS02760
uniprot id: Q0VS69
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

393595:ABO RS06255
gene id: 393595:ABO_RS06255
uniprot id: Q0VQ91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

393595:ABO RS01800
gene id: 393595:ABO_RS01800
uniprot id: Q0VSP7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

393595:ABO RS12295
gene id: 393595:ABO_RS12295
uniprot id: Q0VLU8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS00345
gene id: 393595:ABO_RS00345
uniprot id: Q0VTE6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

393595:ABO RS10500
gene id: 393595:ABO_RS10500
uniprot id: Q0VMV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

393595:ABO RS05465
gene id: 393595:ABO_RS05465
uniprot id: Q0VQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

393595:ABO RS03075
gene id: 393595:ABO_RS03075
uniprot id: Q0VS05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

393595:ABO RS01410
gene id: 393595:ABO_RS01410
uniprot id: Q0VSX3
names: Similarity
messages: Belongs to the HSP15 family.

393595:ABO RS13845
gene id: 393595:ABO_RS13845
uniprot id: Q0VKZ1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

393595:ABO RS12660
gene id: 393595:ABO_RS12660
uniprot id: Q0VLM4
names: Similarity
messages: Belongs to the FrmR/RcnR family.

393595:ABO RS02900
gene id: 393595:ABO_RS02900
uniprot id: Q0VS41
names: Similarity
messages: Belongs to the BolA/IbaG family.

393595:ABO RS05190
gene id: 393595:ABO_RS05190
uniprot id: Q0VQU8
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS08410
gene id: 393595:ABO_RS08410
uniprot id: Q0VP27
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

393595:ABO RS04510
gene id: 393595:ABO_RS04510
uniprot id: Q0VR76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

393595:ABO RS05690
gene id: 393595:ABO_RS05690
uniprot id: Q0VQK0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

393595:ABO RS11880
gene id: 393595:ABO_RS11880
uniprot id: Q0VM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

393595:ABO RS03825
gene id: 393595:ABO_RS03825
uniprot id: Q0VRK9
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS09030
gene id: 393595:ABO_RS09030
uniprot id: Q0VNQ1
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

393595:ABO RS08975
gene id: 393595:ABO_RS08975
uniprot id: Q0VNR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

393595:ABO RS06440
gene id: 393595:ABO_RS06440
uniprot id: Q0VQ55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
messages: Divalent metal cation.
messages: Homotrimer.

393595:ABO RS03975
gene id: 393595:ABO_RS03975
uniprot id: Q0VRI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

393595:ABO RS13240
gene id: 393595:ABO_RS13240
uniprot id: Q0VLA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

393595:ABO RS09885
gene id: 393595:ABO_RS09885
uniprot id: Q0VN80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

393595:ABO RS05485
gene id: 393595:ABO_RS05485
uniprot id: Q0VQN9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

393595:ABO RS00045
gene id: 393595:ABO_RS00045
uniprot id: Q0VT22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

393595:ABO RS08525
gene id: 393595:ABO_RS08525
uniprot id: Q0VP04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

393595:ABO RS00740
gene id: 393595:ABO_RS00740
uniprot id: Q0VTC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

393595:ABO RS12170
gene id: 393595:ABO_RS12170
uniprot id: Q0VLX4
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

393595:ABO RS07580
gene id: 393595:ABO_RS07580
uniprot id: Q0VPI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

393595:ABO RS10340
gene id: 393595:ABO_RS10340
uniprot id: Q0VMZ0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

393595:ABO RS06685
gene id: 393595:ABO_RS06685
uniprot id: Q0VQ06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

393595:ABO RS00955
gene id: 393595:ABO_RS00955
uniprot id: Q0VT82
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

393595:ABO RS01630
gene id: 393595:ABO_RS01630
uniprot id: Q0VSS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

393595:ABO RS05365
gene id: 393595:ABO_RS05365
uniprot id: Q0VQR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

393595:ABO RS11490
gene id: 393595:ABO_RS11490
uniprot id: Q0VMB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

393595:ABO RS10055
gene id: 393595:ABO_RS10055
uniprot id: Q0VN45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

393595:ABO RS11910
gene id: 393595:ABO_RS11910
uniprot id: Q0VM28
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

393595:ABO RS09635
gene id: 393595:ABO_RS09635
uniprot id: Q0VNC8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

393595:ABO RS01435
gene id: 393595:ABO_RS01435
uniprot id: Q0VSW8
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

393595:ABO RS04100
gene id: 393595:ABO_RS04100
uniprot id: Q0VRF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS02745
gene id: 393595:ABO_RS02745
uniprot id: Q0VS72
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

393595:ABO RS06500
gene id: 393595:ABO_RS06500
uniprot id: Q0VQ43
names: Similarity
messages: Belongs to the Lgt family.

393595:ABO RS10905
gene id: 393595:ABO_RS10905
uniprot id: Q0VMM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS12920
gene id: 393595:ABO_RS12920
uniprot id: Q0VLH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

393595:ABO RS09370
gene id: 393595:ABO_RS09370
uniprot id: Q0VNI2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

393595:ABO RS10070
gene id: 393595:ABO_RS10070
uniprot id: Q0VN42
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

393595:ABO RS13650
gene id: 393595:ABO_RS13650
uniprot id: Q0VL29
names: Similarity
messages: Belongs to the GSP E family.

393595:ABO RS02665
gene id: 393595:ABO_RS02665
uniprot id: Q0VS87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS02170
gene id: 393595:ABO_RS02170
uniprot id: Q0VSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

393595:ABO RS13170
gene id: 393595:ABO_RS13170
uniprot id: Q0VLC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

393595:ABO RS04195
gene id: 393595:ABO_RS04195
uniprot id: Q0VRD7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS06805
gene id: 393595:ABO_RS06805
uniprot id: Q0VPY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS10480
gene id: 393595:ABO_RS10480
uniprot id: Q0VMW2
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS08895
gene id: 393595:ABO_RS08895
uniprot id: Q0VNS9
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

393595:ABO RS01980
gene id: 393595:ABO_RS01980
uniprot id: Q0VSM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

393595:ABO RS10365
gene id: 393595:ABO_RS10365
uniprot id: Q0VMY5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

393595:ABO RS01075
gene id: 393595:ABO_RS01075
uniprot id: Q0VT58
names: Similarity
messages: Belongs to the UPF0758 family.

393595:ABO RS06380
gene id: 393595:ABO_RS06380
uniprot id: Q0VQ67
names: Similarity
messages: Belongs to the hyi family.

393595:ABO RS00970
gene id: 393595:ABO_RS00970
uniprot id: Q0VT79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

393595:ABO RS09590
gene id: 393595:ABO_RS09590
uniprot id: Q0VND7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

393595:ABO RS00040
gene id: 393595:ABO_RS00040
uniprot id: Q0VT23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

393595:ABO RS02890
gene id: 393595:ABO_RS02890
uniprot id: Q0VS43
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

393595:ABO RS01715
gene id: 393595:ABO_RS01715
uniprot id: Q0VSR4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

393595:ABO RS00890
gene id: 393595:ABO_RS00890
uniprot id: Q0VT95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

393595:ABO RS02620
gene id: 393595:ABO_RS02620
uniprot id: Q0VS96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

393595:ABO RS00655
gene id: 393595:ABO_RS00655
uniprot id: Q0VTE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

393595:ABO RS03405
gene id: 393595:ABO_RS03405
uniprot id: Q0VRU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

393595:ABO RS06090
gene id: 393595:ABO_RS06090
uniprot id: Q0VQC0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

393595:ABO RS07325
gene id: 393595:ABO_RS07325
uniprot id: Q0VPN5
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS02100
gene id: 393595:ABO_RS02100
uniprot id: Q0VSJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

393595:ABO RS00020
gene id: 393595:ABO_RS00020
uniprot id: Q0VT27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

393595:ABO RS07090
gene id: 393595:ABO_RS07090
uniprot id: Q0VPT2
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS12590
gene id: 393595:ABO_RS12590
uniprot id: Q0VLN8
names: Similarity
messages: Belongs to the thioredoxin family.

393595:ABO RS13140
gene id: 393595:ABO_RS13140
uniprot id: Q0VLC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

393595:ABO RS05570
gene id: 393595:ABO_RS05570
uniprot id: Q0VQM2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

393595:ABO RS10125
gene id: 393595:ABO_RS10125
uniprot id: Q0VN31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

393595:ABO RS10870
gene id: 393595:ABO_RS10870
uniprot id: Q0VMN5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

393595:ABO RS13565
gene id: 393595:ABO_RS13565
uniprot id: Q0VL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

393595:ABO RS07365
gene id: 393595:ABO_RS07365
uniprot id: Q0VPM9
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS00895
gene id: 393595:ABO_RS00895
uniprot id: Q0VT94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

393595:ABO RS13585
gene id: 393595:ABO_RS13585
uniprot id: Q0VL42
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

393595:ABO RS04975
gene id: 393595:ABO_RS04975
uniprot id: Q0VQY8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

393595:ABO RS01690
gene id: 393595:ABO_RS01690
uniprot id: Q0VSR9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

393595:ABO RS05445
gene id: 393595:ABO_RS05445
uniprot id: Q0VQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

393595:ABO RS11680
gene id: 393595:ABO_RS11680
uniprot id: Q0VM74
names: Similarity
messages: Belongs to the peptidase S41A family.

393595:ABO RS04935
gene id: 393595:ABO_RS04935
uniprot id: Q0VQZ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS00450
gene id: 393595:ABO_RS00450
uniprot id: Q0VTK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

393595:ABO RS01310
gene id: 393595:ABO_RS01310
uniprot id: Q0VSZ2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

393595:ABO RS13605
gene id: 393595:ABO_RS13605
uniprot id: Q0VL38
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS03060
gene id: 393595:ABO_RS03060
uniprot id: Q0VS08
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

393595:ABO RS03285
gene id: 393595:ABO_RS03285
uniprot id: Q0VRW4
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS04815
gene id: 393595:ABO_RS04815
uniprot id: Q0VR18
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

393595:ABO RS07750
gene id: 393595:ABO_RS07750
uniprot id: Q0VPF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

393595:ABO RS00215
gene id: 393595:ABO_RS00215
uniprot id: Q0VTL8
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

393595:ABO RS13990
gene id: 393595:ABO_RS13990
uniprot id: Q0VKW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

393595:ABO RS01555
gene id: 393595:ABO_RS01555
uniprot id: Q0VSU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

393595:ABO RS11565
gene id: 393595:ABO_RS11565
uniprot id: Q0VM98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

393595:ABO RS00435
gene id: 393595:ABO_RS00435
uniprot id: Q0VTK8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

393595:ABO RS01270
gene id: 393595:ABO_RS01270
uniprot id: Q0VT00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

393595:ABO RS02355
gene id: 393595:ABO_RS02355
uniprot id: Q0VSE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS02030
gene id: 393595:ABO_RS02030
uniprot id: Q0VSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS12930
gene id: 393595:ABO_RS12930
uniprot id: Q0VLG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

393595:ABO RS13930
gene id: 393595:ABO_RS13930
uniprot id: Q0VKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

393595:ABO RS04310
gene id: 393595:ABO_RS04310
uniprot id: Q0VRB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS09905
gene id: 393595:ABO_RS09905
uniprot id: Q0VN76
names: Similarity
messages: Belongs to the PhoH family.

393595:ABO RS02390
gene id: 393595:ABO_RS02390
uniprot id: Q0VSD9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

393595:ABO RS08160
gene id: 393595:ABO_RS08160
uniprot id: Q0VP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

393595:ABO RS04980
gene id: 393595:ABO_RS04980
uniprot id: Q0VQY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

393595:ABO RS10240
gene id: 393595:ABO_RS10240
uniprot id: Q0VN11
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

393595:ABO RS04170
gene id: 393595:ABO_RS04170
uniprot id: Q0VRE2
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS12575
gene id: 393595:ABO_RS12575
uniprot id: Q0VLP1
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

393595:ABO RS09850
gene id: 393595:ABO_RS09850
uniprot id: Q0VN87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

393595:ABO RS00825
gene id: 393595:ABO_RS00825
uniprot id: Q0VTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

393595:ABO RS10875
gene id: 393595:ABO_RS10875
uniprot id: Q0VMN4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS01600
gene id: 393595:ABO_RS01600
uniprot id: Q0VST5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

393595:ABO RS10130
gene id: 393595:ABO_RS10130
uniprot id: Q0VN30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

393595:ABO RS00115
gene id: 393595:ABO_RS00115
uniprot id: Q0VT09
names: Similarity
messages: Belongs to the HIBADH-related family.

393595:ABO RS09375
gene id: 393595:ABO_RS09375
uniprot id: Q0VNI1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

393595:ABO RS07755
gene id: 393595:ABO_RS07755
uniprot id: Q0VPF4
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

393595:ABO RS06815
gene id: 393595:ABO_RS06815
uniprot id: Q0VPY4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

393595:ABO RS04785
gene id: 393595:ABO_RS04785
uniprot id: Q0VR23
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

393595:ABO RS11550
gene id: 393595:ABO_RS11550
uniprot id: Q0VMA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

393595:ABO RS06220
gene id: 393595:ABO_RS06220
uniprot id: Q0VQ95
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

393595:ABO RS01605
gene id: 393595:ABO_RS01605
uniprot id: Q0VST4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

393595:ABO RS13570
gene id: 393595:ABO_RS13570
uniprot id: Q0VL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

393595:ABO RS13580
gene id: 393595:ABO_RS13580
uniprot id: Q0VL43
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS11730
gene id: 393595:ABO_RS11730
uniprot id: Q0VM64
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

393595:ABO RS02585
gene id: 393595:ABO_RS02585
uniprot id: Q0VSA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

393595:ABO RS08105
gene id: 393595:ABO_RS08105
uniprot id: Q0VP87
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

393595:ABO RS09010
gene id: 393595:ABO_RS09010
uniprot id: Q0VNQ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

393595:ABO RS08795
gene id: 393595:ABO_RS08795
uniprot id: Q0VNU9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS03955
gene id: 393595:ABO_RS03955
uniprot id: Q0VRI4
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

393595:ABO RS09525
gene id: 393595:ABO_RS09525
uniprot id: Q0VNF0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

393595:ABO RS07770
gene id: 393595:ABO_RS07770
uniprot id: Q0VPF1
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

393595:ABO RS13895
gene id: 393595:ABO_RS13895
uniprot id: Q0VKY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

393595:ABO RS02985
gene id: 393595:ABO_RS02985
uniprot id: Q0VS23
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

393595:ABO RS02870
gene id: 393595:ABO_RS02870
uniprot id: Q0VS47
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

393595:ABO RS10725
gene id: 393595:ABO_RS10725
uniprot id: Q0VMR4
names: Similarity
messages: Belongs to the DEAD box helicase family.

393595:ABO RS03215
gene id: 393595:ABO_RS03215
uniprot id: Q0VRX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

393595:ABO RS09600
gene id: 393595:ABO_RS09600
uniprot id: Q0VND5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

393595:ABO RS10195
gene id: 393595:ABO_RS10195
uniprot id: Q0VN20
names: Function
names: Similarity
messages: Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.

393595:ABO RS02510
gene id: 393595:ABO_RS02510
uniprot id: Q0VSB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

393595:ABO RS04835
gene id: 393595:ABO_RS04835
uniprot id: Q0VR14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

393595:ABO RS12305
gene id: 393595:ABO_RS12305
uniprot id: Q0VLU6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS06860
gene id: 393595:ABO_RS06860
uniprot id: Q0VPX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

393595:ABO RS11825
gene id: 393595:ABO_RS11825
uniprot id: Q0VM46
names: Similarity
messages: Belongs to the UPF0111 family.

393595:ABO RS06640
gene id: 393595:ABO_RS06640
uniprot id: Q0VQ15
names: Similarity
messages: Belongs to the ClpA/ClpB family.

393595:ABO RS01515
gene id: 393595:ABO_RS01515
uniprot id: Q0VSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS01730
gene id: 393595:ABO_RS01730
uniprot id: Q0VSR1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

393595:ABO RS10425
gene id: 393595:ABO_RS10425
uniprot id: Q0VMX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

393595:ABO RS07115
gene id: 393595:ABO_RS07115
uniprot id: Q0VPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

393595:ABO RS07440
gene id: 393595:ABO_RS07440
uniprot id: Q0VPL4
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

393595:ABO RS04675
gene id: 393595:ABO_RS04675
uniprot id: Q0VR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

393595:ABO RS04505
gene id: 393595:ABO_RS04505
uniprot id: Q0VR77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

393595:ABO RS03900
gene id: 393595:ABO_RS03900
uniprot id: Q0VRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

393595:ABO RS10520
gene id: 393595:ABO_RS10520
uniprot id: Q0VMV4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

393595:ABO RS10215
gene id: 393595:ABO_RS10215
uniprot id: Q0VN16
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

393595:ABO RS01785
gene id: 393595:ABO_RS01785
uniprot id: Q0VSQ0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

393595:ABO RS04905
gene id: 393595:ABO_RS04905
uniprot id: Q0VR02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

393595:ABO RS04450
gene id: 393595:ABO_RS04450
uniprot id: Q0VR88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

393595:ABO RS04705
gene id: 393595:ABO_RS04705
uniprot id: Q0VR39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

393595:ABO RS02780
gene id: 393595:ABO_RS02780
uniprot id: Q0VS65
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

393595:ABO RS05080
gene id: 393595:ABO_RS05080
uniprot id: Q0VQW7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

393595:ABO RS00180
gene id: 393595:ABO_RS00180
uniprot id: Q0VTM5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

393595:ABO RS08995
gene id: 393595:ABO_RS08995
uniprot id: Q0VNQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

393595:ABO RS08725
gene id: 393595:ABO_RS08725
uniprot id: Q0VNW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

393595:ABO RS11925
gene id: 393595:ABO_RS11925
uniprot id: Q0VM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

393595:ABO RS01055
gene id: 393595:ABO_RS01055
uniprot id: Q0VT62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

393595:ABO RS13345
gene id: 393595:ABO_RS13345
uniprot id: Q0VL88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

393595:ABO RS06670
gene id: 393595:ABO_RS06670
uniprot id: Q0VQ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

393595:ABO RS09425
gene id: 393595:ABO_RS09425
uniprot id: Q0VNH0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

393595:ABO RS12995
gene id: 393595:ABO_RS12995
uniprot id: Q0VLF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

393595:ABO RS09475
gene id: 393595:ABO_RS09475
uniprot id: Q0VNG1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

393595:ABO RS03095
gene id: 393595:ABO_RS03095
uniprot id: Q0VS01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

393595:ABO RS09875
gene id: 393595:ABO_RS09875
uniprot id: Q0VN82
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS13075
gene id: 393595:ABO_RS13075
uniprot id: Q0VLE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

393595:ABO RS11400
gene id: 393595:ABO_RS11400
uniprot id: Q0VMD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

393595:ABO RS00550
gene id: 393595:ABO_RS00550
uniprot id: Q0VTI5
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

393595:ABO RS13725
gene id: 393595:ABO_RS13725
uniprot id: Q0VL14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

393595:ABO RS10100
gene id: 393595:ABO_RS10100
uniprot id: Q0VN36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

393595:ABO RS05005
gene id: 393595:ABO_RS05005
uniprot id: Q0VQY2
names: Similarity
messages: Belongs to the UPF0270 family.

393595:ABO RS08960
gene id: 393595:ABO_RS08960
uniprot id: Q0VNR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm

393595:ABO RS01535
gene id: 393595:ABO_RS01535
uniprot id: Q0VSU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

393595:ABO RS01810
gene id: 393595:ABO_RS01810
uniprot id: Q0VSP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

393595:ABO RS14050
gene id: 393595:ABO_RS14050
uniprot id: Q0VKV1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

393595:ABO RS06405
gene id: 393595:ABO_RS06405
uniprot id: Q0VQ62
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

393595:ABO RS06345
gene id: 393595:ABO_RS06345
uniprot id: Q0VQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

393595:ABO RS12935
gene id: 393595:ABO_RS12935
uniprot id: Q0VLG8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

393595:ABO RS03390
gene id: 393595:ABO_RS03390
uniprot id: Q0VRU4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS04320
gene id: 393595:ABO_RS04320
uniprot id: Q0VRB2
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

393595:ABO RS02920
gene id: 393595:ABO_RS02920
uniprot id: Q0VS37
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

393595:ABO RS13120
gene id: 393595:ABO_RS13120
uniprot id: Q0VLD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

393595:ABO RS05155
gene id: 393595:ABO_RS05155
uniprot id: Q0VQV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

393595:ABO RS04360
gene id: 393595:ABO_RS04360
uniprot id: Q0VRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

393595:ABO RS13815
gene id: 393595:ABO_RS13815
uniprot id: Q0VKZ7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

393595:ABO RS01080
gene id: 393595:ABO_RS01080
uniprot id: Q0VT57
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

393595:ABO RS02150
gene id: 393595:ABO_RS02150
uniprot id: Q0VSI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

393595:ABO RS06820
gene id: 393595:ABO_RS06820
uniprot id: Q0VPY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS05820
gene id: 393595:ABO_RS05820
uniprot id: Q0VQH4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

393595:ABO RS06495
gene id: 393595:ABO_RS06495
uniprot id: Q0VQ44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA).

393595:ABO RS10080
gene id: 393595:ABO_RS10080
uniprot id: Q0VN40
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

393595:ABO RS14010
gene id: 393595:ABO_RS14010
uniprot id: Q0VKV9
names: Cofactor
messages: Can also use Mn(2+) ion.

393595:ABO RS13105
gene id: 393595:ABO_RS13105
uniprot id: Q0VLD5
names: Similarity
messages: Belongs to the peptidase M16 family.

393595:ABO RS03675
gene id: 393595:ABO_RS03675
uniprot id: Q0VRN9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

393595:ABO RS02190
gene id: 393595:ABO_RS02190
uniprot id: Q0VSH8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

393595:ABO RS11180
gene id: 393595:ABO_RS11180
uniprot id: Q0VMH3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

393595:ABO RS05700
gene id: 393595:ABO_RS05700
uniprot id: Q0VQJ8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

393595:ABO RS08500
gene id: 393595:ABO_RS08500
uniprot id: Q0VP09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

393595:ABO RS09825
gene id: 393595:ABO_RS09825
uniprot id: Q0VN92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

393595:ABO RS01035
gene id: 393595:ABO_RS01035
uniprot id: Q0VT66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

393595:ABO RS07735
gene id: 393595:ABO_RS07735
uniprot id: Q0VPF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

393595:ABO RS12745
gene id: 393595:ABO_RS12745
uniprot id: Q0VLK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

393595:ABO RS00590
gene id: 393595:ABO_RS00590
uniprot id: Q0VTH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS02130
gene id: 393595:ABO_RS02130
uniprot id: Q0VSJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

393595:ABO RS04225
gene id: 393595:ABO_RS04225
uniprot id: Q0VRD1
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS01975
gene id: 393595:ABO_RS01975
uniprot id: Q0VSM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

393595:ABO RS09800
gene id: 393595:ABO_RS09800
uniprot id: Q0VN97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS08350
gene id: 393595:ABO_RS08350
uniprot id: Q0VP39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

393595:ABO RS06935
gene id: 393595:ABO_RS06935
uniprot id: Q0VPW0
names: Similarity
messages: Belongs to the universal stress protein A family.

393595:ABO RS02685
gene id: 393595:ABO_RS02685
uniprot id: Q0VS83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

393595:ABO RS06990
gene id: 393595:ABO_RS06990
uniprot id: Q0VPU9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

393595:ABO RS00885
gene id: 393595:ABO_RS00885
uniprot id: Q0VT96
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

393595:ABO RS05810
gene id: 393595:ABO_RS05810
uniprot id: Q0VQH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

393595:ABO RS00795
gene id: 393595:ABO_RS00795
uniprot id: Q0VTB4
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS12960
gene id: 393595:ABO_RS12960
uniprot id: Q0VLG3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

393595:ABO RS03295
gene id: 393595:ABO_RS03295
uniprot id: Q0VRW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

393595:ABO RS13920
gene id: 393595:ABO_RS13920
uniprot id: Q0VKX7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS07535
gene id: 393595:ABO_RS07535
uniprot id: Q0VPJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

393595:ABO RS06620
gene id: 393595:ABO_RS06620
uniprot id: Q0VQ19
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

393595:ABO RS07000
gene id: 393595:ABO_RS07000
uniprot id: Q0VPU7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS11725
gene id: 393595:ABO_RS11725
uniprot id: Q0VM65
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

393595:ABO RS03865
gene id: 393595:ABO_RS03865
uniprot id: Q0VRK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS08200
gene id: 393595:ABO_RS08200
uniprot id: Q0VP69
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS09970
gene id: 393595:ABO_RS09970
uniprot id: Q0VN62
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS04115
gene id: 393595:ABO_RS04115
uniprot id: Q0VRF3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

393595:ABO RS05645
gene id: 393595:ABO_RS05645
uniprot id: Q0VQK7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

393595:ABO RS01645
gene id: 393595:ABO_RS01645
uniprot id: Q0VSS6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

393595:ABO RS09470
gene id: 393595:ABO_RS09470
uniprot id: Q0VNG2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

393595:ABO RS11465
gene id: 393595:ABO_RS11465
uniprot id: Q0VMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

393595:ABO RS03050
gene id: 393595:ABO_RS03050
uniprot id: Q0VS10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

393595:ABO RS12245
gene id: 393595:ABO_RS12245
uniprot id: Q0VLV9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

393595:ABO RS07445
gene id: 393595:ABO_RS07445
uniprot id: Q0VPL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS01805
gene id: 393595:ABO_RS01805
uniprot id: Q0VSP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS12585
gene id: 393595:ABO_RS12585
uniprot id: Q0VLN9
names: Similarity
messages: Belongs to the GppA/Ppx family.

393595:ABO RS12940
gene id: 393595:ABO_RS12940
uniprot id: Q0VLG7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS11560
gene id: 393595:ABO_RS11560
uniprot id: Q0VM99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

393595:ABO RS12175
gene id: 393595:ABO_RS12175
uniprot id: Q0VLX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

393595:ABO RS08090
gene id: 393595:ABO_RS08090
uniprot id: Q0VP90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

393595:ABO RS13540
gene id: 393595:ABO_RS13540
uniprot id: Q0VL50
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

393595:ABO RS00785
gene id: 393595:ABO_RS00785
uniprot id: Q0VTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).

393595:ABO RS03515
gene id: 393595:ABO_RS03515
uniprot id: Q0VRS0
names: Function
names: Similarity
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

393595:ABO RS03275
gene id: 393595:ABO_RS03275
uniprot id: Q0VRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

393595:ABO RS06115
gene id: 393595:ABO_RS06115
uniprot id: Q0VQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

393595:ABO RS10035
gene id: 393595:ABO_RS10035
uniprot id: Q0VN49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

393595:ABO RS09155
gene id: 393595:ABO_RS09155
uniprot id: Q0VNM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

393595:ABO RS11125
gene id: 393595:ABO_RS11125
uniprot id: Q0VMI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

393595:ABO RS11830
gene id: 393595:ABO_RS11830
uniprot id: Q0VM45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

393595:ABO RS04230
gene id: 393595:ABO_RS04230
uniprot id: Q0VRD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

393595:ABO RS10075
gene id: 393595:ABO_RS10075
uniprot id: Q0VN41
names: Similarity
messages: Belongs to the peptidase S11 family.

393595:ABO RS11235
gene id: 393595:ABO_RS11235
uniprot id: Q0VMG2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

393595:ABO RS11895
gene id: 393595:ABO_RS11895
uniprot id: Q0VM31
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

393595:ABO RS05935
gene id: 393595:ABO_RS05935
uniprot id: Q0VQF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

393595:ABO RS11165
gene id: 393595:ABO_RS11165
uniprot id: Q0VMH6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

393595:ABO RS10015
gene id: 393595:ABO_RS10015
uniprot id: Q0VN53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

393595:ABO RS10805
gene id: 393595:ABO_RS10805
uniprot id: Q0VMP7
names: Similarity
messages: Belongs to the UPF0434 family.

393595:ABO RS02005
gene id: 393595:ABO_RS02005
uniprot id: Q0VSL6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

393595:ABO RS06335
gene id: 393595:ABO_RS06335
uniprot id: Q0VQ76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

393595:ABO RS07625
gene id: 393595:ABO_RS07625
uniprot id: Q0VPH8
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS03915
gene id: 393595:ABO_RS03915
uniprot id: Q0VRJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

393595:ABO RS06225
gene id: 393595:ABO_RS06225
uniprot id: Q0VQ94
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

393595:ABO RS06600
gene id: 393595:ABO_RS06600
uniprot id: Q0VQ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

393595:ABO RS01115
gene id: 393595:ABO_RS01115
uniprot id: Q0VT51
names: Similarity
messages: Belongs to the GSP E family.

393595:ABO RS01830
gene id: 393595:ABO_RS01830
uniprot id: Q0VSP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

393595:ABO RS11395
gene id: 393595:ABO_RS11395
uniprot id: Q0VMD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

393595:ABO RS07700
gene id: 393595:ABO_RS07700
uniprot id: Q0VPG5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

393595:ABO RS00935
gene id: 393595:ABO_RS00935
uniprot id: Q0VT86
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS06745
gene id: 393595:ABO_RS06745
uniprot id: Q0VPZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

393595:ABO RS08380
gene id: 393595:ABO_RS08380
uniprot id: Q0VP33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

393595:ABO RS05085
gene id: 393595:ABO_RS05085
uniprot id: Q0VQW6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS04315
gene id: 393595:ABO_RS04315
uniprot id: Q0VRB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

393595:ABO RS11760
gene id: 393595:ABO_RS11760
uniprot id: Q0VM58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

393595:ABO RS13835
gene id: 393595:ABO_RS13835
uniprot id: Q0VKZ3
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Binds 2 Fe(3+) ions per subunit.
messages: Catalyzes the hydroxylation of n-alkanes and fatty acids in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C5-C12 hydrocarbons.
messages: Cell inner membrane
messages: Induced by AlkS and n-alkanes.

393595:ABO RS04125
gene id: 393595:ABO_RS04125
uniprot id: Q0VRF1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

393595:ABO RS13805
gene id: 393595:ABO_RS13805
uniprot id: Q0VKZ9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

393595:ABO RS11335
gene id: 393595:ABO_RS11335
uniprot id: Q0VME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

393595:ABO RS13880
gene id: 393595:ABO_RS13880
uniprot id: Q0VKY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

393595:ABO RS07380
gene id: 393595:ABO_RS07380
uniprot id: Q0VPM6
names: Similarity
messages: Belongs to the glutamate synthase family.

393595:ABO RS10585
gene id: 393595:ABO_RS10585
uniprot id: Q0VMU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

393595:ABO RS00765
gene id: 393595:ABO_RS00765
uniprot id: Q0VTB9
names: Subcellular Location Annotation
messages: Cytoplasm

393595:ABO RS02805
gene id: 393595:ABO_RS02805
uniprot id: Q0VS60
names: Similarity
messages: Belongs to the peptidase U62 family.

393595:ABO RS10590
gene id: 393595:ABO_RS10590
uniprot id: Q0VMU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

393595:ABO RS02770
gene id: 393595:ABO_RS02770
uniprot id: Q0VS67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

393595:ABO RS13375
gene id: 393595:ABO_RS13375
uniprot id: Q0VL82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

393595:ABO RS13060
gene id: 393595:ABO_RS13060
uniprot id: Q0VLE4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

393595:ABO RS11225
gene id: 393595:ABO_RS11225
uniprot id: Q0VMG4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

393595:ABO RS08205
gene id: 393595:ABO_RS08205
uniprot id: Q0VP68
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

393595:ABO RS03120
gene id: 393595:ABO_RS03120
uniprot id: Q0VRZ6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

393595:ABO RS07875
gene id: 393595:ABO_RS07875
uniprot id: Q0VPD2
names: Similarity
messages: Belongs to the UPF0276 family.

393595:ABO RS09785
gene id: 393595:ABO_RS09785
uniprot id: Q0VNA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

393595:ABO RS06690
gene id: 393595:ABO_RS06690
uniprot id: Q0VQ05
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

393595:ABO RS07495
gene id: 393595:ABO_RS07495
uniprot id: Q0VPK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

393595:ABO RS06580
gene id: 393595:ABO_RS06580
uniprot id: Q0VQ27
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

393595:ABO RS06200
gene id: 393595:ABO_RS06200
uniprot id: Q0VQ99
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

393595:ABO RS05550
gene id: 393595:ABO_RS05550
uniprot id: Q0VQM6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

393595:ABO RS06650
gene id: 393595:ABO_RS06650
uniprot id: Q0VQ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

393595:ABO RS11170
gene id: 393595:ABO_RS11170
uniprot id: Q0VMH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

393595:ABO RS07830
gene id: 393595:ABO_RS07830
uniprot id: Q0VPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

393595:ABO RS03210
gene id: 393595:ABO_RS03210
uniprot id: Q0VRX8
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

393595:ABO RS09260
gene id: 393595:ABO_RS09260
uniprot id: Q0VNK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

393595:ABO RS08470
gene id: 393595:ABO_RS08470
uniprot id: Q0VP15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

393595:ABO RS07630
gene id: 393595:ABO_RS07630
uniprot id: Q0VPH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

393595:ABO RS12715
gene id: 393595:ABO_RS12715
uniprot id: Q0VLL2
names: Similarity
messages: Belongs to the CvfB family.

393595:ABO RS12755
gene id: 393595:ABO_RS12755
uniprot id: Q0VLK4
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

393595:ABO RS02480
gene id: 393595:ABO_RS02480
uniprot id: Q0VSC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

393595:ABO RS06480
gene id: 393595:ABO_RS06480
uniprot id: Q0VQ47
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

393595:ABO RS13960
gene id: 393595:ABO_RS13960
uniprot id: Q0VKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

393595:ABO RS11240
gene id: 393595:ABO_RS11240
uniprot id: Q0VMG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

393595:ABO RS05930
gene id: 393595:ABO_RS05930
uniprot id: Q0VQF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS11500
gene id: 393595:ABO_RS11500
uniprot id: Q0VMB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

393595:ABO RS04445
gene id: 393595:ABO_RS04445
uniprot id: Q0VR89
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

393595:ABO RS02095
gene id: 393595:ABO_RS02095
uniprot id: Q0VSJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

393595:ABO RS10525
gene id: 393595:ABO_RS10525
uniprot id: Q0VMV3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

393595:ABO RS00625
gene id: 393595:ABO_RS00625
uniprot id: Q0VTH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

393595:ABO RS09480
gene id: 393595:ABO_RS09480
uniprot id: Q0VNG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

393595:ABO RS11135
gene id: 393595:ABO_RS11135
uniprot id: Q0VMI2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

393595:ABO RS10850
gene id: 393595:ABO_RS10850
uniprot id: Q0VMN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS10515
gene id: 393595:ABO_RS10515
uniprot id: Q0VMV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

393595:ABO RS04495
gene id: 393595:ABO_RS04495
uniprot id: Q0VR79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

393595:ABO RS04640
gene id: 393595:ABO_RS04640
uniprot id: Q0VR52
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

393595:ABO RS13765
gene id: 393595:ABO_RS13765
uniprot id: Q0VL06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

393595:ABO RS01860
gene id: 393595:ABO_RS01860
uniprot id: Q0VSN5
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS08180
gene id: 393595:ABO_RS08180
uniprot id: Q0VP73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

393595:ABO RS09005
gene id: 393595:ABO_RS09005
uniprot id: Q0VNQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

393595:ABO RS13255
gene id: 393595:ABO_RS13255
uniprot id: Q0VLA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

393595:ABO RS07715
gene id: 393595:ABO_RS07715
uniprot id: Q0VPG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

393595:ABO RS10570
gene id: 393595:ABO_RS10570
uniprot id: Q0VMU4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

393595:ABO RS10955
gene id: 393595:ABO_RS10955
uniprot id: Q0VML7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS09535
gene id: 393595:ABO_RS09535
uniprot id: Q0VNE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

393595:ABO RS02070
gene id: 393595:ABO_RS02070
uniprot id: Q0VSK3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

393595:ABO RS05840
gene id: 393595:ABO_RS05840
uniprot id: Q0VQH0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

393595:ABO RS07400
gene id: 393595:ABO_RS07400
uniprot id: Q0VPM2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

393595:ABO RS05205
gene id: 393595:ABO_RS05205
uniprot id: Q0VQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

393595:ABO RS02540
gene id: 393595:ABO_RS02540
uniprot id: Q0VSB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

393595:ABO RS13710
gene id: 393595:ABO_RS13710
uniprot id: Q0VL17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS13355
gene id: 393595:ABO_RS13355
uniprot id: Q0VL86
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

393595:ABO RS08930
gene id: 393595:ABO_RS08930
uniprot id: Q0VNS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS02375
gene id: 393595:ABO_RS02375
uniprot id: Q0VSE2
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

393595:ABO RS11495
gene id: 393595:ABO_RS11495
uniprot id: Q0VMB1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

393595:ABO RS02575
gene id: 393595:ABO_RS02575
uniprot id: Q0VSA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

393595:ABO RS08010
gene id: 393595:ABO_RS08010
uniprot id: Q0VPA6
names: Similarity
messages: Belongs to the ArsC family.

393595:ABO RS02320
gene id: 393595:ABO_RS02320
uniprot id: Q0VSF3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS12200
gene id: 393595:ABO_RS12200
uniprot id: Q0VLW8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

393595:ABO RS02035
gene id: 393595:ABO_RS02035
uniprot id: Q0VSL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgJ family.
messages: Cell inner membrane
messages: Periplasm

393595:ABO RS12665
gene id: 393595:ABO_RS12665
uniprot id: Q0VLM3
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS05470
gene id: 393595:ABO_RS05470
uniprot id: Q0VQP2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

393595:ABO RS05240
gene id: 393595:ABO_RS05240
uniprot id: Q0VQT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

393595:ABO RS06795
gene id: 393595:ABO_RS06795
uniprot id: Q0VPY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

393595:ABO RS07375
gene id: 393595:ABO_RS07375
uniprot id: Q0VPM7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

393595:ABO RS06660
gene id: 393595:ABO_RS06660
uniprot id: Q0VQ11
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

393595:ABO RS02120
gene id: 393595:ABO_RS02120
uniprot id: Q0VSJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

393595:ABO RS08235
gene id: 393595:ABO_RS08235
uniprot id: Q0VP63
names: Similarity
messages: Belongs to the transglycosylase Slt family.

393595:ABO RS06325
gene id: 393595:ABO_RS06325
uniprot id: Q0VQ78
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

393595:ABO RS04910
gene id: 393595:ABO_RS04910
uniprot id: Q0VR01
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

393595:ABO RS04575
gene id: 393595:ABO_RS04575
uniprot id: Q0VR66
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

393595:ABO RS11415
gene id: 393595:ABO_RS11415
uniprot id: Q0VMC7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS03035
gene id: 393595:ABO_RS03035
uniprot id: Q0VS13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

393595:ABO RS05740
gene id: 393595:ABO_RS05740
uniprot id: Q0VQJ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

393595:ABO RS12635
gene id: 393595:ABO_RS12635
uniprot id: Q0VLM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

393595:ABO RS04295
gene id: 393595:ABO_RS04295
uniprot id: Q0VRB7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS09045
gene id: 393595:ABO_RS09045
uniprot id: Q0VNP8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS04485
gene id: 393595:ABO_RS04485
uniprot id: Q0VR81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

393595:ABO RS11325
gene id: 393595:ABO_RS11325
uniprot id: Q0VME5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

393595:ABO RS13110
gene id: 393595:ABO_RS13110
uniprot id: Q0VLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

393595:ABO RS09775
gene id: 393595:ABO_RS09775
uniprot id: Q0VNA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

393595:ABO RS07935
gene id: 393595:ABO_RS07935
uniprot id: Q0VPC0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

393595:ABO RS06590
gene id: 393595:ABO_RS06590
uniprot id: Q0VQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

393595:ABO RS11110
gene id: 393595:ABO_RS11110
uniprot id: Q0VMI7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

393595:ABO RS11745
gene id: 393595:ABO_RS11745
uniprot id: Q0VM61
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

393595:ABO RS07745
gene id: 393595:ABO_RS07745
uniprot id: Q0VPF6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

393595:ABO RS00325
gene id: 393595:ABO_RS00325
uniprot id: Q0VTF0
names: Similarity
messages: Belongs to the hemerythrin family.

393595:ABO RS06215
gene id: 393595:ABO_RS06215
uniprot id: Q0VQ96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

393595:ABO RS10325
gene id: 393595:ABO_RS10325
uniprot id: Q0VMZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS03185
gene id: 393595:ABO_RS03185
uniprot id: Q0VRY3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

393595:ABO RS00880
gene id: 393595:ABO_RS00880
uniprot id: Q0VT97
names: Similarity
messages: Belongs to the RutC family.

393595:ABO RS04300
gene id: 393595:ABO_RS04300
uniprot id: Q0VRB6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

393595:ABO RS05695
gene id: 393595:ABO_RS05695
uniprot id: Q0VQJ9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

393595:ABO RS09595
gene id: 393595:ABO_RS09595
uniprot id: Q0VND6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

393595:ABO RS07805
gene id: 393595:ABO_RS07805
uniprot id: Q0VPE4
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

393595:ABO RS03045
gene id: 393595:ABO_RS03045
uniprot id: Q0VS11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

393595:ABO RS05510
gene id: 393595:ABO_RS05510
uniprot id: Q0VQN4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

393595:ABO RS00005
gene id: 393595:ABO_RS00005
uniprot id: Q0VT30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

393595:ABO RS02850
gene id: 393595:ABO_RS02850
uniprot id: Q0VS51
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

393595:ABO RS12780
gene id: 393595:ABO_RS12780
uniprot id: Q0VLJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

393595:ABO RS05325
gene id: 393595:ABO_RS05325
uniprot id: Q0VQS1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

393595:ABO RS09515
gene id: 393595:ABO_RS09515
uniprot id: Q0VNF2
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS11175
gene id: 393595:ABO_RS11175
uniprot id: Q0VMH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS05320
gene id: 393595:ABO_RS05320
uniprot id: Q0VQS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

393595:ABO RS13635
gene id: 393595:ABO_RS13635
uniprot id: Q0VL32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

393595:ABO RS05970
gene id: 393595:ABO_RS05970
uniprot id: Q0VQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

393595:ABO RS13925
gene id: 393595:ABO_RS13925
uniprot id: Q0VKX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

393595:ABO RS04500
gene id: 393595:ABO_RS04500
uniprot id: Q0VR78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

393595:ABO RS14020
gene id: 393595:ABO_RS14020
uniprot id: Q0VKV7
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

393595:ABO RS03005
gene id: 393595:ABO_RS03005
uniprot id: Q0VS19
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

393595:ABO RS09560
gene id: 393595:ABO_RS09560
uniprot id: Q0VNE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

393595:ABO RS03670
gene id: 393595:ABO_RS03670
uniprot id: Q0VRP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

393595:ABO RS09995
gene id: 393595:ABO_RS09995
uniprot id: Q0VN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

393595:ABO RS13685
gene id: 393595:ABO_RS13685
uniprot id: Q0VL22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

393595:ABO RS00820
gene id: 393595:ABO_RS00820
uniprot id: Q0VTA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Cytoplasm
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

393595:ABO RS05105
gene id: 393595:ABO_RS05105
uniprot id: Q0VQW2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS10750
gene id: 393595:ABO_RS10750
uniprot id: Q0VMQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

393595:ABO RS00155
gene id: 393595:ABO_RS00155
uniprot id: Q0VTN0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

393595:ABO RS01395
gene id: 393595:ABO_RS01395
uniprot id: Q0VSX6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

393595:ABO RS07230
gene id: 393595:ABO_RS07230
uniprot id: Q0VPQ5
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS11455
gene id: 393595:ABO_RS11455
uniprot id: Q0VMB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS06300
gene id: 393595:ABO_RS06300
uniprot id: Q0VQ83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

393595:ABO RS12580
gene id: 393595:ABO_RS12580
uniprot id: Q0VLP0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

393595:ABO RS12125
gene id: 393595:ABO_RS12125
uniprot id: Q0VLY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

393595:ABO RS04055
gene id: 393595:ABO_RS04055
uniprot id: Q0VRG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

393595:ABO RS02465
gene id: 393595:ABO_RS02465
uniprot id: Q0VSC4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

393595:ABO RS05955
gene id: 393595:ABO_RS05955
uniprot id: Q0VQE8
names: Similarity
messages: Belongs to the skp family.

393595:ABO RS02360
gene id: 393595:ABO_RS02360
uniprot id: Q0VSE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

393595:ABO RS05520
gene id: 393595:ABO_RS05520
uniprot id: Q0VQN2
names: Similarity
messages: Belongs to the fabD family.

393595:ABO RS02080
gene id: 393595:ABO_RS02080
uniprot id: Q0VSK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

393595:ABO RS14065
gene id: 393595:ABO_RS14065
uniprot id: Q0VKU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

393595:ABO RS07295
gene id: 393595:ABO_RS07295
uniprot id: Q0VPP2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

393595:ABO RS02145
gene id: 393595:ABO_RS02145
uniprot id: Q0VSI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

393595:ABO RS09510
gene id: 393595:ABO_RS09510
uniprot id: Q0VNF3
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS00670
gene id: 393595:ABO_RS00670
uniprot id: Q0VTD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

393595:ABO RS07225
gene id: 393595:ABO_RS07225
uniprot id: Q0VPQ6
names: Similarity
messages: Belongs to the YciI family.

393595:ABO RS07635
gene id: 393595:ABO_RS07635
uniprot id: Q0VPH6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

393595:ABO RS00565
gene id: 393595:ABO_RS00565
uniprot id: Q0VTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

393595:ABO RS11030
gene id: 393595:ABO_RS11030
uniprot id: Q0VMK3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

393595:ABO RS09620
gene id: 393595:ABO_RS09620
uniprot id: Q0VND1
names: Similarity
messages: Belongs to the HesB/IscA family.

393595:ABO RS04020
gene id: 393595:ABO_RS04020
uniprot id: Q0VRH1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

393595:ABO RS02365
gene id: 393595:ABO_RS02365
uniprot id: Q0VSE4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

393595:ABO RS08535
gene id: 393595:ABO_RS08535
uniprot id: Q0VP02
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS13950
gene id: 393595:ABO_RS13950
uniprot id: Q0VKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

393595:ABO RS11090
gene id: 393595:ABO_RS11090
uniprot id: Q0VMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

393595:ABO RS09015
gene id: 393595:ABO_RS09015
uniprot id: Q0VNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

393595:ABO RS11045
gene id: 393595:ABO_RS11045
uniprot id: Q0VMK0
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

393595:ABO RS11815
gene id: 393595:ABO_RS11815
uniprot id: Q0VM48
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

393595:ABO RS12825
gene id: 393595:ABO_RS12825
uniprot id: Q0VLJ0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

393595:ABO RS07610
gene id: 393595:ABO_RS07610
uniprot id: Q0VPI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

393595:ABO RS13905
gene id: 393595:ABO_RS13905
uniprot id: Q0VKY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

393595:ABO RS02725
gene id: 393595:ABO_RS02725
uniprot id: Q0VS76
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

393595:ABO RS05000
gene id: 393595:ABO_RS05000
uniprot id: Q0VQY3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

393595:ABO RS06470
gene id: 393595:ABO_RS06470
uniprot id: Q0VQ49
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

393595:ABO RS12020
gene id: 393595:ABO_RS12020
uniprot id: Q0VM05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

393595:ABO RS14075
gene id: 393595:ABO_RS14075
uniprot id: Q0VKU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

393595:ABO RS02235
gene id: 393595:ABO_RS02235
uniprot id: Q0VSG9
names: Similarity
messages: Belongs to the GSP N family.

393595:ABO RS09780
gene id: 393595:ABO_RS09780
uniprot id: Q0VNA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

393595:ABO RS08015
gene id: 393595:ABO_RS08015
uniprot id: Q0VPA5
names: Similarity
messages: Belongs to the WrbA family.

393595:ABO RS04130
gene id: 393595:ABO_RS04130
uniprot id: Q0VRF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

393595:ABO RS06605
gene id: 393595:ABO_RS06605
uniprot id: Q0VQ22
names: Similarity
messages: Belongs to the MoaD family.

393595:ABO RS07760
gene id: 393595:ABO_RS07760
uniprot id: Q0VPF3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

393595:ABO RS02160
gene id: 393595:ABO_RS02160
uniprot id: Q0VSI5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

393595:ABO RS01340
gene id: 393595:ABO_RS01340
uniprot id: Q0VSY7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

393595:ABO RS06140
gene id: 393595:ABO_RS06140
uniprot id: Q0VQB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

393595:ABO RS08710
gene id: 393595:ABO_RS08710
uniprot id: Q0VNW7
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

393595:ABO RS13250
gene id: 393595:ABO_RS13250
uniprot id: Q0VLA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

393595:ABO RS02690
gene id: 393595:ABO_RS02690
uniprot id: Q0VS82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

393595:ABO RS07410
gene id: 393595:ABO_RS07410
uniprot id: Q0VPM0
names: Similarity
messages: Belongs to the PrpF family.

393595:ABO RS13115
gene id: 393595:ABO_RS13115
uniprot id: Q0VLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

393595:ABO RS08460
gene id: 393595:ABO_RS08460
uniprot id: Q0VP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

393595:ABO RS00225
gene id: 393595:ABO_RS00225
uniprot id: Q0VTL6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

393595:ABO RS05790
gene id: 393595:ABO_RS05790
uniprot id: Q0VQI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

393595:ABO RS08375
gene id: 393595:ABO_RS08375
uniprot id: Q0VP34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

393595:ABO RS01610
gene id: 393595:ABO_RS01610
uniprot id: Q0VST3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

393595:ABO RS13790
gene id: 393595:ABO_RS13790
uniprot id: Q0VL02
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

393595:ABO RS06040
gene id: 393595:ABO_RS06040
uniprot id: Q0VQD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

393595:ABO RS02180
gene id: 393595:ABO_RS02180
uniprot id: Q0VSI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

393595:ABO RS05285
gene id: 393595:ABO_RS05285
uniprot id: Q0VQS9
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.

393595:ABO RS01565
gene id: 393595:ABO_RS01565
uniprot id: Q0VSU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

393595:ABO RS12415
gene id: 393595:ABO_RS12415
uniprot id: Q0VLS3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

393595:ABO RS02640
gene id: 393595:ABO_RS02640
uniprot id: Q0VS92
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

393595:ABO RS08890
gene id: 393595:ABO_RS08890
uniprot id: Q0VNT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

393595:ABO RS03710
gene id: 393595:ABO_RS03710
uniprot id: Q0VRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

393595:ABO RS05705
gene id: 393595:ABO_RS05705
uniprot id: Q0VQJ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS07160
gene id: 393595:ABO_RS07160
uniprot id: Q0VPR9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

393595:ABO RS09270
gene id: 393595:ABO_RS09270
uniprot id: Q0VNK2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

393595:ABO RS09125
gene id: 393595:ABO_RS09125
uniprot id: Q0VNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

393595:ABO RS05950
gene id: 393595:ABO_RS05950
uniprot id: Q0VQE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

393595:ABO RS12595
gene id: 393595:ABO_RS12595
uniprot id: Q0VLN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

393595:ABO RS04400
gene id: 393595:ABO_RS04400
uniprot id: Q0VR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

393595:ABO RS02000
gene id: 393595:ABO_RS02000
uniprot id: Q0VSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

393595:ABO RS03025
gene id: 393595:ABO_RS03025
uniprot id: Q0VS15
names: Similarity
messages: Belongs to the UPF0102 family.

393595:ABO RS07150
gene id: 393595:ABO_RS07150
uniprot id: Q0VPS1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

393595:ABO RS08145
gene id: 393595:ABO_RS08145
uniprot id: Q0VP80
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

393595:ABO RS00120
gene id: 393595:ABO_RS00120
uniprot id: Q0VTN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

393595:ABO RS08510
gene id: 393595:ABO_RS08510
uniprot id: Q0VP07
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

393595:ABO RS00475
gene id: 393595:ABO_RS00475
uniprot id: Q0VTK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

393595:ABO RS05290
gene id: 393595:ABO_RS05290
uniprot id: Q0VQS8
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS06855
gene id: 393595:ABO_RS06855
uniprot id: Q0VPX6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

393595:ABO RS04950
gene id: 393595:ABO_RS04950
uniprot id: Q0VQZ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS00010
gene id: 393595:ABO_RS00010
uniprot id: Q0VT29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

393595:ABO RS09275
gene id: 393595:ABO_RS09275
uniprot id: Q0VNK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

393595:ABO RS12105
gene id: 393595:ABO_RS12105
uniprot id: Q0VLY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

393595:ABO RS13935
gene id: 393595:ABO_RS13935
uniprot id: Q0VKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

393595:ABO RS13195
gene id: 393595:ABO_RS13195
uniprot id: Q0VLB7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

393595:ABO RS09330
gene id: 393595:ABO_RS09330
uniprot id: Q0VNJ0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

393595:ABO RS11610
gene id: 393595:ABO_RS11610
uniprot id: Q0VM88
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

393595:ABO RS02820
gene id: 393595:ABO_RS02820
uniprot id: Q0VS57
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS04880
gene id: 393595:ABO_RS04880
uniprot id: Q0VR06
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

393595:ABO RS01700
gene id: 393595:ABO_RS01700
uniprot id: Q0VSR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

393595:ABO RS01770
gene id: 393595:ABO_RS01770
uniprot id: Q0VSQ3
names: Similarity
messages: Belongs to the SfsA family.

393595:ABO RS10020
gene id: 393595:ABO_RS10020
uniprot id: Q0VN52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

393595:ABO RS00380
gene id: 393595:ABO_RS00380
uniprot id: Q0VKT8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

393595:ABO RS09960
gene id: 393595:ABO_RS09960
uniprot id: Q0VN64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

393595:ABO RS02660
gene id: 393595:ABO_RS02660
uniprot id: Q0VS88
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

393595:ABO RS12605
gene id: 393595:ABO_RS12605
uniprot id: Q0VLN5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

393595:ABO RS07030
gene id: 393595:ABO_RS07030
uniprot id: Q0VPU3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

393595:ABO RS04385
gene id: 393595:ABO_RS04385
uniprot id: Q0VRA0
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS13420
gene id: 393595:ABO_RS13420
uniprot id: Q0VL74
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

393595:ABO RS10890
gene id: 393595:ABO_RS10890
uniprot id: Q0VMN1
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS01330
gene id: 393595:ABO_RS01330
uniprot id: Q0VSY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

393595:ABO RS02110
gene id: 393595:ABO_RS02110
uniprot id: Q0VSJ5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

393595:ABO RS04145
gene id: 393595:ABO_RS04145
uniprot id: Q0VRE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

393595:ABO RS06265
gene id: 393595:ABO_RS06265
uniprot id: Q0VQ89
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

393595:ABO RS00830
gene id: 393595:ABO_RS00830
uniprot id: Q0VTA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

393595:ABO RS00025
gene id: 393595:ABO_RS00025
uniprot id: Q0VT26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

393595:ABO RS09360
gene id: 393595:ABO_RS09360
uniprot id: Q0VNI4
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS02495
gene id: 393595:ABO_RS02495
uniprot id: Q0VSB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

393595:ABO RS14225
gene id: 393595:ABO_RS14225
uniprot id: Q0VQ20
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

393595:ABO RS01820
gene id: 393595:ABO_RS01820
uniprot id: Q0VSP3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

393595:ABO RS07920
gene id: 393595:ABO_RS07920
uniprot id: Q0VPC3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

393595:ABO RS05830
gene id: 393595:ABO_RS05830
uniprot id: Q0VQH2
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

393595:ABO RS02195
gene id: 393595:ABO_RS02195
uniprot id: Q0VSH7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

393595:ABO RS06475
gene id: 393595:ABO_RS06475
uniprot id: Q0VQ48
names: Similarity
messages: Belongs to the BolA/IbaG family.

393595:ABO RS12150
gene id: 393595:ABO_RS12150
uniprot id: Q0VLX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

393595:ABO RS02675
gene id: 393595:ABO_RS02675
uniprot id: Q0VS85
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

393595:ABO RS01965
gene id: 393595:ABO_RS01965
uniprot id: Q0VSM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

393595:ABO RS01825
gene id: 393595:ABO_RS01825
uniprot id: Q0VSP2
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS03170
gene id: 393595:ABO_RS03170
uniprot id: Q0VRY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

393595:ABO RS13460
gene id: 393595:ABO_RS13460
uniprot id: Q0VL66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

393595:ABO RS06185
gene id: 393595:ABO_RS06185
uniprot id: Q0VQA1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

393595:ABO RS12345
gene id: 393595:ABO_RS12345
uniprot id: Q0VLT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

393595:ABO RS01985
gene id: 393595:ABO_RS01985
uniprot id: Q0VSM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

393595:ABO RS07540
gene id: 393595:ABO_RS07540
uniprot id: Q0VPJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS07485
gene id: 393595:ABO_RS07485
uniprot id: Q0VPK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

393595:ABO RS02165
gene id: 393595:ABO_RS02165
uniprot id: Q0VSI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

393595:ABO RS02380
gene id: 393595:ABO_RS02380
uniprot id: Q0VSE1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

393595:ABO RS02420
gene id: 393595:ABO_RS02420
uniprot id: Q0VSD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

393595:ABO RS00950
gene id: 393595:ABO_RS00950
uniprot id: Q0VT83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS05225
gene id: 393595:ABO_RS05225
uniprot id: Q0VQU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

393595:ABO RS03065
gene id: 393595:ABO_RS03065
uniprot id: Q0VS07
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm

393595:ABO RS08560
gene id: 393595:ABO_RS08560
uniprot id: Q0VNZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

393595:ABO RS13535
gene id: 393595:ABO_RS13535
uniprot id: Q0VL51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

393595:ABO RS12740
gene id: 393595:ABO_RS12740
uniprot id: Q0VLK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

393595:ABO RS10550
gene id: 393595:ABO_RS10550
uniprot id: Q0VMU8
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

393595:ABO RS11365
gene id: 393595:ABO_RS11365
uniprot id: Q0VMD7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

393595:ABO RS10265
gene id: 393595:ABO_RS10265
uniprot id: Q0VN06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

393595:ABO RS03085
gene id: 393595:ABO_RS03085
uniprot id: Q0VS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that is essential for cell division.

393595:ABO RS13945
gene id: 393595:ABO_RS13945
uniprot id: Q0VKX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

393595:ABO RS05340
gene id: 393595:ABO_RS05340
uniprot id: Q0VQR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

393595:ABO RS02905
gene id: 393595:ABO_RS02905
uniprot id: Q0VS40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

393595:ABO RS01010
gene id: 393595:ABO_RS01010
uniprot id: Q0VM62
names: Similarity
messages: Belongs to the cytochrome P450 family.

393595:ABO RS03885
gene id: 393595:ABO_RS03885
uniprot id: Q0VRJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

393595:ABO RS11655
gene id: 393595:ABO_RS11655
uniprot id: Q0VM79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

393595:ABO RS11820
gene id: 393595:ABO_RS11820
uniprot id: Q0VM47
names: Similarity
messages: Belongs to the GSP E family.

393595:ABO RS14025
gene id: 393595:ABO_RS14025
uniprot id: Q0VKV6
names: Subcellular Location Annotation
messages: Cytoplasm

393595:ABO RS01400
gene id: 393595:ABO_RS01400
uniprot id: Q0VSX5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

393595:ABO RS09095
gene id: 393595:ABO_RS09095
uniprot id: Q0VNN8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

393595:ABO RS10160
gene id: 393595:ABO_RS10160
uniprot id: Q0VN24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

393595:ABO RS02680
gene id: 393595:ABO_RS02680
uniprot id: Q0VS84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

393595:ABO RS06530
gene id: 393595:ABO_RS06530
uniprot id: Q0VQ37
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS02345
gene id: 393595:ABO_RS02345
uniprot id: Q0VSE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

393595:ABO RS04340
gene id: 393595:ABO_RS04340
uniprot id: Q0VRA8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

393595:ABO RS11115
gene id: 393595:ABO_RS11115
uniprot id: Q0VMI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

393595:ABO RS02595
gene id: 393595:ABO_RS02595
uniprot id: Q0VSA1
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS00035
gene id: 393595:ABO_RS00035
uniprot id: Q0VT24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS06540
gene id: 393595:ABO_RS06540
uniprot id: Q0VQ35
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

393595:ABO RS12275
gene id: 393595:ABO_RS12275
uniprot id: Q0VLV2
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

393595:ABO RS01685
gene id: 393595:ABO_RS01685
uniprot id: Q0VSS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

393595:ABO RS03790
gene id: 393595:ABO_RS03790
uniprot id: Q0VRL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

393595:ABO RS12565
gene id: 393595:ABO_RS12565
uniprot id: Q0VLP3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

393595:ABO RS11645
gene id: 393595:ABO_RS11645
uniprot id: Q0VM81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS00730
gene id: 393595:ABO_RS00730
uniprot id: Q0VTC7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

393595:ABO RS06340
gene id: 393595:ABO_RS06340
uniprot id: Q0VQ75
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

393595:ABO RS07740
gene id: 393595:ABO_RS07740
uniprot id: Q0VPF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

393595:ABO RS06165
gene id: 393595:ABO_RS06165
uniprot id: Q0VQA5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

393595:ABO RS04265
gene id: 393595:ABO_RS04265
uniprot id: Q0VRC3
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS11945
gene id: 393595:ABO_RS11945
uniprot id: Q0VM21
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS13745
gene id: 393595:ABO_RS13745
uniprot id: Q0VL10
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

393595:ABO RS10780
gene id: 393595:ABO_RS10780
uniprot id: Q0VMQ3
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

393595:ABO RS07720
gene id: 393595:ABO_RS07720
uniprot id: Q0VPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

393595:ABO RS12830
gene id: 393595:ABO_RS12830
uniprot id: Q0VLI9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

393595:ABO RS08000
gene id: 393595:ABO_RS08000
uniprot id: Q0VPA8
names: Similarity
messages: Belongs to the acylphosphatase family.

393595:ABO RS08400
gene id: 393595:ABO_RS08400
uniprot id: Q0VP29
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

393595:ABO RS04800
gene id: 393595:ABO_RS04800
uniprot id: Q0VR21
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS04660
gene id: 393595:ABO_RS04660
uniprot id: Q0VR48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

393595:ABO RS01670
gene id: 393595:ABO_RS01670
uniprot id: Q0VSS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

393595:ABO RS06945
gene id: 393595:ABO_RS06945
uniprot id: Q0VPV8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS02350
gene id: 393595:ABO_RS02350
uniprot id: Q0VSE7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

393595:ABO RS05275
gene id: 393595:ABO_RS05275
uniprot id: Q0VQT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

393595:ABO RS03640
gene id: 393595:ABO_RS03640
uniprot id: Q0VRP6
names: Similarity
messages: Belongs to the TPP enzyme family.

393595:ABO RS03895
gene id: 393595:ABO_RS03895
uniprot id: Q0VRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

393595:ABO RS12215
gene id: 393595:ABO_RS12215
uniprot id: Q0VLW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

393595:ABO RS11410
gene id: 393595:ABO_RS11410
uniprot id: Q0VMC8
names: Similarity
messages: Belongs to the ComB family.

393595:ABO RS11590
gene id: 393595:ABO_RS11590
uniprot id: Q0VM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

393595:ABO RS11540
gene id: 393595:ABO_RS11540
uniprot id: Q0VMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

393595:ABO RS09295
gene id: 393595:ABO_RS09295
uniprot id: Q0VNJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

393595:ABO RS06585
gene id: 393595:ABO_RS06585
uniprot id: Q0VQ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

393595:ABO RS03350
gene id: 393595:ABO_RS03350
uniprot id: Q0VRV1
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

393595:ABO RS09870
gene id: 393595:ABO_RS09870
uniprot id: Q0VN83
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

393595:ABO RS00705
gene id: 393595:ABO_RS00705
uniprot id: Q0VTD2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

393595:ABO RS08800
gene id: 393595:ABO_RS08800
uniprot id: Q0VNU8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS12545
gene id: 393595:ABO_RS12545
uniprot id: Q0VLP7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS05940
gene id: 393595:ABO_RS05940
uniprot id: Q0VQF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS02765
gene id: 393595:ABO_RS02765
uniprot id: Q0VS68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

393595:ABO RS13645
gene id: 393595:ABO_RS13645
uniprot id: Q0VL30
names: Similarity
messages: Belongs to the GSP E family.

393595:ABO RS07780
gene id: 393595:ABO_RS07780
uniprot id: Q0VPE9
names: Similarity
messages: Belongs to the citrate synthase family.

393595:ABO RS11340
gene id: 393595:ABO_RS11340
uniprot id: Q0VME2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS12210
gene id: 393595:ABO_RS12210
uniprot id: Q0VLW6
names: Similarity
messages: Belongs to the cytochrome P450 family.

393595:ABO RS00140
gene id: 393595:ABO_RS00140
uniprot id: Q0VTN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

393595:ABO RS02990
gene id: 393595:ABO_RS02990
uniprot id: Q0VS22
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

393595:ABO RS14000
gene id: 393595:ABO_RS14000
uniprot id: Q0VKW1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS01325
gene id: 393595:ABO_RS01325
uniprot id: Q0VSY9
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS02755
gene id: 393595:ABO_RS02755
uniprot id: Q0VS70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

393595:ABO RS00110
gene id: 393595:ABO_RS00110
uniprot id: Q0VT10
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS05710
gene id: 393595:ABO_RS05710
uniprot id: Q0VQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

393595:ABO RS02720
gene id: 393595:ABO_RS02720
uniprot id: Q0VS77
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

393595:ABO RS01300
gene id: 393595:ABO_RS01300
uniprot id: Q0VSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

393595:ABO RS12110
gene id: 393595:ABO_RS12110
uniprot id: Q0VLY7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

393595:ABO RS06680
gene id: 393595:ABO_RS06680
uniprot id: Q0VQ07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

393595:ABO RS09025
gene id: 393595:ABO_RS09025
uniprot id: Q0VNQ2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

393595:ABO RS11705
gene id: 393595:ABO_RS11705
uniprot id: Q0VM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

393595:ABO RS01285
gene id: 393595:ABO_RS01285
uniprot id: Q0VSZ7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

393595:ABO RS01710
gene id: 393595:ABO_RS01710
uniprot id: Q0VSR5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

393595:ABO RS04305
gene id: 393595:ABO_RS04305
uniprot id: Q0VRB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

393595:ABO RS04160
gene id: 393595:ABO_RS04160
uniprot id: Q0VRE4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

393595:ABO RS05850
gene id: 393595:ABO_RS05850
uniprot id: Q0VQG8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell inner membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

393595:ABO RS06235
gene id: 393595:ABO_RS06235
uniprot id: Q0VQ92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

393595:ABO RS11665
gene id: 393595:ABO_RS11665
uniprot id: Q0VM77
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

393595:ABO RS03495
gene id: 393595:ABO_RS03495
uniprot id: Q0VRS4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

393595:ABO RS05200
gene id: 393595:ABO_RS05200
uniprot id: Q0VQU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

393595:ABO RS11970
gene id: 393595:ABO_RS11970
uniprot id: Q0VM16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

393595:ABO RS10150
gene id: 393595:ABO_RS10150
uniprot id: Q0VN26
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

393595:ABO RS10530
gene id: 393595:ABO_RS10530
uniprot id: Q0VMV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

393595:ABO RS11505
gene id: 393595:ABO_RS11505
uniprot id: Q0VMA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

393595:ABO RS08125
gene id: 393595:ABO_RS08125
uniprot id: Q0VP83
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

393595:ABO RS07990
gene id: 393595:ABO_RS07990
uniprot id: Q0VPB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

393595:ABO RS01775
gene id: 393595:ABO_RS01775
uniprot id: Q0VSQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

393595:ABO RS10600
gene id: 393595:ABO_RS10600
uniprot id: Q0VMT8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

393595:ABO RS05780
gene id: 393595:ABO_RS05780
uniprot id: Q0VQI2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

393595:ABO RS01050
gene id: 393595:ABO_RS01050
uniprot id: Q0VT63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

393595:ABO RS05945
gene id: 393595:ABO_RS05945
uniprot id: Q0VQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

393595:ABO RS05860
gene id: 393595:ABO_RS05860
uniprot id: Q0VQG6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

393595:ABO RS12645
gene id: 393595:ABO_RS12645
uniprot id: Q0VLM7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

393595:ABO RS11700
gene id: 393595:ABO_RS11700
uniprot id: Q0VM70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

393595:ABO RS07480
gene id: 393595:ABO_RS07480
uniprot id: Q0VPK6
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

393595:ABO RS05500
gene id: 393595:ABO_RS05500
uniprot id: Q0VQN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

393595:ABO RS05450
gene id: 393595:ABO_RS05450
uniprot id: Q0VQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

393595:ABO RS07395
gene id: 393595:ABO_RS07395
uniprot id: Q0VPM3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

393595:ABO RS14015
gene id: 393595:ABO_RS14015
uniprot id: Q0VKV8
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

393595:ABO RS05900
gene id: 393595:ABO_RS05900
uniprot id: Q0VQF9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

393595:ABO RS05370
gene id: 393595:ABO_RS05370
uniprot id: Q0VQR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

393595:ABO RS10120
gene id: 393595:ABO_RS10120
uniprot id: Q0VN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

393595:ABO RS09755
gene id: 393595:ABO_RS09755
uniprot id: Q0VNA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

393595:ABO RS07855
gene id: 393595:ABO_RS07855
uniprot id: Q0VPD6
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

393595:ABO RS09040
gene id: 393595:ABO_RS09040
uniprot id: Q0VNP9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

393595:ABO RS02230
gene id: 393595:ABO_RS02230
uniprot id: Q0VSH0
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

393595:ABO RS11750
gene id: 393595:ABO_RS11750
uniprot id: Q0VM60
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

393595:ABO RS11955
gene id: 393595:ABO_RS11955
uniprot id: Q0VM19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

393595:ABO RS05545
gene id: 393595:ABO_RS05545
uniprot id: Q0VQM7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

393595:ABO RS12470
gene id: 393595:ABO_RS12470
uniprot id: Q0VLR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

393595:ABO RS00480
gene id: 393595:ABO_RS00480
uniprot id: Q0VTJ9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

393595:ABO RS03055
gene id: 393595:ABO_RS03055
uniprot id: Q0VS09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

393595:ABO RS02630
gene id: 393595:ABO_RS02630
uniprot id: Q0VS94
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

393595:ABO RS01405
gene id: 393595:ABO_RS01405
uniprot id: Q0VSX4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

393595:ABO RS01755
gene id: 393595:ABO_RS01755
uniprot id: Q0VSQ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS04850
gene id: 393595:ABO_RS04850
uniprot id: Q0VR11
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS04150
gene id: 393595:ABO_RS04150
uniprot id: Q0VRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

393595:ABO RS13705
gene id: 393595:ABO_RS13705
uniprot id: Q0VL18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

393595:ABO RS13630
gene id: 393595:ABO_RS13630
uniprot id: Q0VL33
names: Similarity
messages: Belongs to the YggT family.

393595:ABO RS07205
gene id: 393595:ABO_RS07205
uniprot id: Q0VPR0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

393595:ABO RS03190
gene id: 393595:ABO_RS03190
uniprot id: Q0VRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS02670
gene id: 393595:ABO_RS02670
uniprot id: Q0VS86
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

393595:ABO RS10050
gene id: 393595:ABO_RS10050
uniprot id: Q0VN46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

393595:ABO RS12400
gene id: 393595:ABO_RS12400
uniprot id: Q0VLS6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

393595:ABO RS10800
gene id: 393595:ABO_RS10800
uniprot id: Q0VMP8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

393595:ABO RS11445
gene id: 393595:ABO_RS11445
uniprot id: Q0VMC1
names: Similarity
messages: Belongs to the glutamate synthase family.

393595:ABO RS12100
gene id: 393595:ABO_RS12100
uniprot id: Q0VLY9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

393595:ABO RS13305
gene id: 393595:ABO_RS13305
uniprot id: Q0VL96
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

393595:ABO RS00680
gene id: 393595:ABO_RS00680
uniprot id: Q0VTD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

393595:ABO RS09150
gene id: 393595:ABO_RS09150
uniprot id: Q0VNM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

393595:ABO RS11905
gene id: 393595:ABO_RS11905
uniprot id: Q0VM29
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

393595:ABO RS04120
gene id: 393595:ABO_RS04120
uniprot id: Q0VRF2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

393595:ABO RS00555
gene id: 393595:ABO_RS00555
uniprot id: Q0VTI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

393595:ABO RS02115
gene id: 393595:ABO_RS02115
uniprot id: Q0VSJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

393595:ABO RS11285
gene id: 393595:ABO_RS11285
uniprot id: Q0VMF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

393595:ABO RS05355
gene id: 393595:ABO_RS05355
uniprot id: Q0VQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

393595:ABO RS06230
gene id: 393595:ABO_RS06230
uniprot id: Q0VQ93
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

393595:ABO RS13100
gene id: 393595:ABO_RS13100
uniprot id: Q0VLD6
names: Similarity
messages: Belongs to the peptidase M16 family.

393595:ABO RS08355
gene id: 393595:ABO_RS08355
uniprot id: Q0VP38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

393595:ABO RS00130
gene id: 393595:ABO_RS00130
uniprot id: Q0VTN5
names: Similarity
messages: Belongs to the pirin family.

393595:ABO RS03020
gene id: 393595:ABO_RS03020
uniprot id: Q0VS16
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

393595:ABO RS03560
gene id: 393595:ABO_RS03560
uniprot id: Q0VRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

393595:ABO RS13940
gene id: 393595:ABO_RS13940
uniprot id: Q0VKX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

393595:ABO RS05885
gene id: 393595:ABO_RS05885
uniprot id: Q0VQG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS04585
gene id: 393595:ABO_RS04585
uniprot id: Q0VR64
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

393595:ABO RS13310
gene id: 393595:ABO_RS13310
uniprot id: Q0VL95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

393595:ABO RS10305
gene id: 393595:ABO_RS10305
uniprot id: Q0VMZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

393595:ABO RS04240
gene id: 393595:ABO_RS04240
uniprot id: Q0VRC8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

393595:ABO RS13205
gene id: 393595:ABO_RS13205
uniprot id: Q0VLB5
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS03925
gene id: 393595:ABO_RS03925
uniprot id: Q0VRI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS02885
gene id: 393595:ABO_RS02885
uniprot id: Q0VS44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

393595:ABO RS01680
gene id: 393595:ABO_RS01680
uniprot id: Q0VSS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

393595:ABO RS12850
gene id: 393595:ABO_RS12850
uniprot id: Q0VLI5
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS03340
gene id: 393595:ABO_RS03340
uniprot id: Q0VRV3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

393595:ABO RS03870
gene id: 393595:ABO_RS03870
uniprot id: Q0VRK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

393595:ABO RS05995
gene id: 393595:ABO_RS05995
uniprot id: Q0VQE0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

393595:ABO RS00530
gene id: 393595:ABO_RS00530
uniprot id: Q0VTI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
messages: Membrane

393595:ABO RS02645
gene id: 393595:ABO_RS02645
uniprot id: Q0VS91
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

393595:ABO RS10060
gene id: 393595:ABO_RS10060
uniprot id: Q0VN44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

393595:ABO RS05640
gene id: 393595:ABO_RS05640
uniprot id: Q0VQK8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

393595:ABO RS08680
gene id: 393595:ABO_RS08680
uniprot id: Q0VNX3
names: Similarity
messages: Belongs to the Fur family.

393595:ABO RS12625
gene id: 393595:ABO_RS12625
uniprot id: Q0VLM4
names: Similarity
messages: Belongs to the FrmR/RcnR family.

393595:ABO RS03100
gene id: 393595:ABO_RS03100
uniprot id: Q0VS00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

393595:ABO RS13550
gene id: 393595:ABO_RS13550
uniprot id: Q0VL48
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

393595:ABO RS07330
gene id: 393595:ABO_RS07330
uniprot id: Q0VPN6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS10460
gene id: 393595:ABO_RS10460
uniprot id: Q0VMW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

393595:ABO RS06645
gene id: 393595:ABO_RS06645
uniprot id: Q0VQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

393595:ABO RS01105
gene id: 393595:ABO_RS01105
uniprot id: Q0VT53
names: Similarity
messages: Belongs to the bacterial secretin family.

393595:ABO RS07490
gene id: 393595:ABO_RS07490
uniprot id: Q0VPK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

393595:ABO RS03565
gene id: 393595:ABO_RS03565
uniprot id: Q0VRR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

393595:ABO RS03930
gene id: 393595:ABO_RS03930
uniprot id: Q0VRI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

393595:ABO RS00585
gene id: 393595:ABO_RS00585
uniprot id: Q0VTH8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

393595:ABO RS12630
gene id: 393595:ABO_RS12630
uniprot id: Q0VLN0
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS00635
gene id: 393595:ABO_RS00635
uniprot id: Q0VTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Membrane

393595:ABO RS13885
gene id: 393595:ABO_RS13885
uniprot id: Q0VKY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

393595:ABO RS01245
gene id: 393595:ABO_RS01245
uniprot id: Q0VT05
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS06715
gene id: 393595:ABO_RS06715
uniprot id: Q0VQ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

393595:ABO RS09575
gene id: 393595:ABO_RS09575
uniprot id: Q0VNE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

393595:ABO RS04005
gene id: 393595:ABO_RS04005
uniprot id: Q0VRH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

393595:ABO RS01180
gene id: 393595:ABO_RS01180
uniprot id: Q0VT40
names: Subcellular Location Annotation
messages: Membrane

393595:ABO RS09505
gene id: 393595:ABO_RS09505
uniprot id: Q0VNF5
names: Similarity
messages: Belongs to the catalase family.

393595:ABO RS09530
gene id: 393595:ABO_RS09530
uniprot id: Q0VNE9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

393595:ABO RS03150
gene id: 393595:ABO_RS03150
uniprot id: Q0VRZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

393595:ABO RS08425
gene id: 393595:ABO_RS08425
uniprot id: Q0VP24
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

393595:ABO RS10410
gene id: 393595:ABO_RS10410
uniprot id: Q0VMX6
names: Similarity
messages: Belongs to the TrpC family.

393595:ABO RS01935
gene id: 393595:ABO_RS01935
uniprot id: Q0VSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

393595:ABO RS00865
gene id: 393595:ABO_RS00865
uniprot id: Q0VTA0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

393595:ABO RS02700
gene id: 393595:ABO_RS02700
uniprot id: Q0VS81
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

393595:ABO RS09380
gene id: 393595:ABO_RS09380
uniprot id: Q0VNI0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.