391936:S7S RS00595
gene id: 391936:S7S_RS00595
uniprot id: A0A0B4XJ03
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

391936:S7S RS01970
gene id: 391936:S7S_RS01970
uniprot id: A0A0B4XK74
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

391936:S7S RS18325
gene id: 391936:S7S_RS18325
uniprot id: A0A0B4XUY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

391936:S7S RS16560
gene id: 391936:S7S_RS16560
uniprot id: A0A0B4XT68
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

391936:S7S RS12315
gene id: 391936:S7S_RS12315
uniprot id: A0A0B4XKQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

391936:S7S RS04565
gene id: 391936:S7S_RS04565
uniprot id: A0A0B4XLU1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

391936:S7S RS09675
gene id: 391936:S7S_RS09675
uniprot id: A0A0B4XQ04
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS13960
gene id: 391936:S7S_RS13960
uniprot id: A0A0B4XSD1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

391936:S7S RS01985
gene id: 391936:S7S_RS01985
uniprot id: A0A0B4XJF3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

391936:S7S RS04115
gene id: 391936:S7S_RS04115
uniprot id: A0A0B4XLI3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

391936:S7S RS06845
gene id: 391936:S7S_RS06845
uniprot id: A0A0B4XN96
names: Similarity
messages: Belongs to the pirin family.

391936:S7S RS00850
gene id: 391936:S7S_RS00850
uniprot id: A0A0B4XJ51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

391936:S7S RS01665
gene id: 391936:S7S_RS01665
uniprot id: A0A0B4XK05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

391936:S7S RS01500
gene id: 391936:S7S_RS01500
uniprot id: A0A0B4XJI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

391936:S7S RS14995
gene id: 391936:S7S_RS14995
uniprot id: A0A0B4XQB1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

391936:S7S RS06085
gene id: 391936:S7S_RS06085
uniprot id: A0A0B4XM54
names: Similarity
messages: Belongs to the acylphosphatase family.

391936:S7S RS11270
gene id: 391936:S7S_RS11270
uniprot id: A0A0B4XK41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

391936:S7S RS09130
gene id: 391936:S7S_RS09130
uniprot id: A0A0B4XIU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

391936:S7S RS04515
gene id: 391936:S7S_RS04515
uniprot id: A0A0B4XLT1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

391936:S7S RS10925
gene id: 391936:S7S_RS10925
uniprot id: A0A0B4XNC4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

391936:S7S RS10185
gene id: 391936:S7S_RS10185
uniprot id: A0A0B4XNT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

391936:S7S RS16725
gene id: 391936:S7S_RS16725
uniprot id: A0A0B4XMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

391936:S7S RS01980
gene id: 391936:S7S_RS01980
uniprot id: A0A0B4XFJ3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

391936:S7S RS04215
gene id: 391936:S7S_RS04215
uniprot id: A0A0B4XLL6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

391936:S7S RS15085
gene id: 391936:S7S_RS15085
uniprot id: A0A0B4XRL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

391936:S7S RS03220
gene id: 391936:S7S_RS03220
uniprot id: A0A0B4XJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

391936:S7S RS01790
gene id: 391936:S7S_RS01790
uniprot id: A0A0B4XK31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

391936:S7S RS06605
gene id: 391936:S7S_RS06605
uniprot id: A0A0B4XHT6
names: Similarity
messages: Belongs to the PrpD family.

391936:S7S RS15275
gene id: 391936:S7S_RS15275
uniprot id: A0A0B4XQL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

391936:S7S RS06030
gene id: 391936:S7S_RS06030
uniprot id: A0A0B4XMR8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

391936:S7S RS08810
gene id: 391936:S7S_RS08810
uniprot id: A0A0B4XIP8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

391936:S7S RS18320
gene id: 391936:S7S_RS18320
uniprot id: A0A0B4XSA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

391936:S7S RS10250
gene id: 391936:S7S_RS10250
uniprot id: A0A0B4XPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

391936:S7S RS02890
gene id: 391936:S7S_RS02890
uniprot id: A0A0B4XG30
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

391936:S7S RS09705
gene id: 391936:S7S_RS09705
uniprot id: A0A0B4XPF2
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

391936:S7S RS03955
gene id: 391936:S7S_RS03955
uniprot id: A0A0B4XKH8
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS17345
gene id: 391936:S7S_RS17345
uniprot id: A0A0B4XUB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

391936:S7S RS15370
gene id: 391936:S7S_RS15370
uniprot id: A0A0B4XRU1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS08305
gene id: 391936:S7S_RS08305
uniprot id: A0A0B4XLR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

391936:S7S RS17000
gene id: 391936:S7S_RS17000
uniprot id: A0A0B4XU37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

391936:S7S RS06930
gene id: 391936:S7S_RS06930
uniprot id: A0A0B4XI06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

391936:S7S RS07250
gene id: 391936:S7S_RS07250
uniprot id: A0A0B4XMX6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

391936:S7S RS04895
gene id: 391936:S7S_RS04895
uniprot id: A0A0B4XLG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

391936:S7S RS18435
gene id: 391936:S7S_RS18435
uniprot id: A0A0B4XNZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

391936:S7S RS05920
gene id: 391936:S7S_RS05920
uniprot id: A0A0B4XKI0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

391936:S7S RS07140
gene id: 391936:S7S_RS07140
uniprot id: A0A0B4XNG3
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

391936:S7S RS17805
gene id: 391936:S7S_RS17805
uniprot id: A0A0B4XU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

391936:S7S RS18025
gene id: 391936:S7S_RS18025
uniprot id: A0A0B4XUS3
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

391936:S7S RS16420
gene id: 391936:S7S_RS16420
uniprot id: A0A0B4XT41
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

391936:S7S RS18555
gene id: 391936:S7S_RS18555
uniprot id: A0A0B4XUE3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

391936:S7S RS08700
gene id: 391936:S7S_RS08700
uniprot id: A0A0B4XPD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

391936:S7S RS08930
gene id: 391936:S7S_RS08930
uniprot id: A0A0B4XNX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

391936:S7S RS03820
gene id: 391936:S7S_RS03820
uniprot id: A0A0B4XLB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

391936:S7S RS01000
gene id: 391936:S7S_RS01000
uniprot id: A0A0B4XF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

391936:S7S RS04965
gene id: 391936:S7S_RS04965
uniprot id: A0A0B4XM41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS08005
gene id: 391936:S7S_RS08005
uniprot id: A0A0B4XLM0
names: Similarity
messages: Belongs to the citrate synthase family.

391936:S7S RS13220
gene id: 391936:S7S_RS13220
uniprot id: A0A0B4XPG9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

391936:S7S RS14985
gene id: 391936:S7S_RS14985
uniprot id: A0A0B4XM76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

391936:S7S RS11450
gene id: 391936:S7S_RS11450
uniprot id: A0A0B4XPL8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

391936:S7S RS07340
gene id: 391936:S7S_RS07340
uniprot id: A0A0B4XL80
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS04390
gene id: 391936:S7S_RS04390
uniprot id: A0A0B4XLQ0
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

391936:S7S RS04570
gene id: 391936:S7S_RS04570
uniprot id: A0A0B4XL91
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

391936:S7S RS08235
gene id: 391936:S7S_RS08235
uniprot id: A0A0B4XP47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

391936:S7S RS00125
gene id: 391936:S7S_RS00125
uniprot id: A0A0B4XEN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS13130
gene id: 391936:S7S_RS13130
uniprot id: A0A0B4XS07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS09775
gene id: 391936:S7S_RS09775
uniprot id: A0A0B4XQ18
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

391936:S7S RS10820
gene id: 391936:S7S_RS10820
uniprot id: A0A0B4XP80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

391936:S7S RS14010
gene id: 391936:S7S_RS14010
uniprot id: A0A0B4XSE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

391936:S7S RS04325
gene id: 391936:S7S_RS04325
uniprot id: A0A0B4XGP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

391936:S7S RS09945
gene id: 391936:S7S_RS09945
uniprot id: A0A0B4XNP3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

391936:S7S RS13735
gene id: 391936:S7S_RS13735
uniprot id: A0A0B4XS96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

391936:S7S RS05445
gene id: 391936:S7S_RS05445
uniprot id: A0A0B4XLU6
names: Similarity
messages: Belongs to the Lgt family.

391936:S7S RS16570
gene id: 391936:S7S_RS16570
uniprot id: A0A0B4XSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

391936:S7S RS18420
gene id: 391936:S7S_RS18420
uniprot id: A0A0B4XSB1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

391936:S7S RS06500
gene id: 391936:S7S_RS06500
uniprot id: A0A0B4XM07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

391936:S7S RS08300
gene id: 391936:S7S_RS08300
uniprot id: A0A0B4XMZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS14750
gene id: 391936:S7S_RS14750
uniprot id: A0A0B4XSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

391936:S7S RS06240
gene id: 391936:S7S_RS06240
uniprot id: A0A0B4XHL4
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS14825
gene id: 391936:S7S_RS14825
uniprot id: A0A0B4XSR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

391936:S7S RS12990
gene id: 391936:S7S_RS12990
uniprot id: A0A0B4XQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS16675
gene id: 391936:S7S_RS16675
uniprot id: A0A0B4XMW0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

391936:S7S RS06425
gene id: 391936:S7S_RS06425
uniprot id: A0A0B4XLZ0
names: Subcellular Location Annotation
messages: Cytoplasm

391936:S7S RS12490
gene id: 391936:S7S_RS12490
uniprot id: A0A0B4XKU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

391936:S7S RS13235
gene id: 391936:S7S_RS13235
uniprot id: A0A0B4XLB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

391936:S7S RS12625
gene id: 391936:S7S_RS12625
uniprot id: A0A0B4XP94
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

391936:S7S RS16620
gene id: 391936:S7S_RS16620
uniprot id: A0A0B4XT79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

391936:S7S RS12210
gene id: 391936:S7S_RS12210
uniprot id: A0A0B4XQX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

391936:S7S RS02060
gene id: 391936:S7S_RS02060
uniprot id: A0A0B4XJG9
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

391936:S7S RS15725
gene id: 391936:S7S_RS15725
uniprot id: A0A0B4XQT3
names: Similarity
messages: Belongs to the DinB family.

391936:S7S RS18645
gene id: 391936:S7S_RS18645
uniprot id: A0A0B4XTV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

391936:S7S RS07475
gene id: 391936:S7S_RS07475
uniprot id: A0A0B4XN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

391936:S7S RS12510
gene id: 391936:S7S_RS12510
uniprot id: A0A0B4XR37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

391936:S7S RS10245
gene id: 391936:S7S_RS10245
uniprot id: A0A0B4XQE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

391936:S7S RS18375
gene id: 391936:S7S_RS18375
uniprot id: A0A0B4XUY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

391936:S7S RS08410
gene id: 391936:S7S_RS08410
uniprot id: A0A0B4XN06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

391936:S7S RS14890
gene id: 391936:S7S_RS14890
uniprot id: A0A0B4XRG7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

391936:S7S RS14090
gene id: 391936:S7S_RS14090
uniprot id: A0A0B4XRW9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

391936:S7S RS18475
gene id: 391936:S7S_RS18475
uniprot id: A0A0B4XV08
names: Similarity
messages: Belongs to the band 7/mec-2 family.

391936:S7S RS15540
gene id: 391936:S7S_RS15540
uniprot id: A0A0B4XMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

391936:S7S RS01760
gene id: 391936:S7S_RS01760
uniprot id: A0A0B4XI75
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

391936:S7S RS00650
gene id: 391936:S7S_RS00650
uniprot id: A0A0B4XEW1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

391936:S7S RS01630
gene id: 391936:S7S_RS01630
uniprot id: A0A0B4XJ72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

391936:S7S RS16040
gene id: 391936:S7S_RS16040
uniprot id: A0A0B4XSZ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

391936:S7S RS15975
gene id: 391936:S7S_RS15975
uniprot id: A0A0B4XS44
names: Similarity
messages: Belongs to the SfsA family.

391936:S7S RS16415
gene id: 391936:S7S_RS16415
uniprot id: A0A0B4XTQ1
names: Similarity
messages: Belongs to the AHA1 family.

391936:S7S RS15625
gene id: 391936:S7S_RS15625
uniprot id: A0A0B4XQS1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

391936:S7S RS18345
gene id: 391936:S7S_RS18345
uniprot id: A0A0B4XSA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

391936:S7S RS14800
gene id: 391936:S7S_RS14800
uniprot id: A0A0B4XSR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

391936:S7S RS17320
gene id: 391936:S7S_RS17320
uniprot id: A0A0B4XUB1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

391936:S7S RS03740
gene id: 391936:S7S_RS03740
uniprot id: A0A0B4XJE5
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

391936:S7S RS14075
gene id: 391936:S7S_RS14075
uniprot id: A0A0B4XQZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

391936:S7S RS06745
gene id: 391936:S7S_RS06745
uniprot id: A0A0B4XN75
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

391936:S7S RS04430
gene id: 391936:S7S_RS04430
uniprot id: A0A0B4XKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

391936:S7S RS07445
gene id: 391936:S7S_RS07445
uniprot id: A0A0B4XNN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

391936:S7S RS00120
gene id: 391936:S7S_RS00120
uniprot id: A0A0B4XIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS10160
gene id: 391936:S7S_RS10160
uniprot id: A0A0B4XNT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

391936:S7S RS09080
gene id: 391936:S7S_RS09080
uniprot id: A0A0B4XPN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

391936:S7S RS02660
gene id: 391936:S7S_RS02660
uniprot id: A0A0B4XKT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS08325
gene id: 391936:S7S_RS08325
uniprot id: A0A0B4XN00
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

391936:S7S RS04820
gene id: 391936:S7S_RS04820
uniprot id: A0A0B4XLF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

391936:S7S RS10830
gene id: 391936:S7S_RS10830
uniprot id: A0A0B4XQP8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

391936:S7S RS02390
gene id: 391936:S7S_RS02390
uniprot id: A0A0B4XKH9
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

391936:S7S RS12670
gene id: 391936:S7S_RS12670
uniprot id: A0A0B4XKY9
names: Similarity
messages: Belongs to the universal stress protein A family.

391936:S7S RS18530
gene id: 391936:S7S_RS18530
uniprot id: A0A0B4XUD8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

391936:S7S RS08885
gene id: 391936:S7S_RS08885
uniprot id: A0A0B4XIQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

391936:S7S RS03950
gene id: 391936:S7S_RS03950
uniprot id: A0A0B4XKU7
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS04665
gene id: 391936:S7S_RS04665
uniprot id: A0A0B4XLW7
names: Similarity
messages: Belongs to the UPF0175 family.
messages: Belongs to the phD/YefM antitoxin family.

391936:S7S RS03830
gene id: 391936:S7S_RS03830
uniprot id: A0A0B4XGE9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

391936:S7S RS03315
gene id: 391936:S7S_RS03315
uniprot id: A0A0B4XKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

391936:S7S RS02830
gene id: 391936:S7S_RS02830
uniprot id: A0A0B4XKV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

391936:S7S RS06310
gene id: 391936:S7S_RS06310
uniprot id: A0A0B4XM95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

391936:S7S RS07085
gene id: 391936:S7S_RS07085
uniprot id: A0A0B4XL31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

391936:S7S RS12115
gene id: 391936:S7S_RS12115
uniprot id: A0A0B4XKK8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

391936:S7S RS09965
gene id: 391936:S7S_RS09965
uniprot id: A0A0B4XMR0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS17060
gene id: 391936:S7S_RS17060
uniprot id: A0A0B4XN52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS04230
gene id: 391936:S7S_RS04230
uniprot id: A0A0B4XKQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

391936:S7S RS14015
gene id: 391936:S7S_RS14015
uniprot id: A0A0B4XRV3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

391936:S7S RS17375
gene id: 391936:S7S_RS17375
uniprot id: A0A0B4XTP1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

391936:S7S RS11380
gene id: 391936:S7S_RS11380
uniprot id: A0A0B4XNK2
names: Similarity
messages: Belongs to the rubredoxin family.

391936:S7S RS01805
gene id: 391936:S7S_RS01805
uniprot id: A0A0B4XJB4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

391936:S7S RS08490
gene id: 391936:S7S_RS08490
uniprot id: A0A0B4XN13
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

391936:S7S RS01995
gene id: 391936:S7S_RS01995
uniprot id: A0A0B4XK81
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS06335
gene id: 391936:S7S_RS06335
uniprot id: A0A0B4XM99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

391936:S7S RS08035
gene id: 391936:S7S_RS08035
uniprot id: A0A0B4XP11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

391936:S7S RS09805
gene id: 391936:S7S_RS09805
uniprot id: A0A0B4XPI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

391936:S7S RS16555
gene id: 391936:S7S_RS16555
uniprot id: A0A0B4XTT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

391936:S7S RS01475
gene id: 391936:S7S_RS01475
uniprot id: A0A0B4XJH7
names: Similarity
messages: Belongs to the peptidase S41A family.

391936:S7S RS09215
gene id: 391936:S7S_RS09215
uniprot id: A0A0B4XM70
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

391936:S7S RS09195
gene id: 391936:S7S_RS09195
uniprot id: A0A0B4XPQ4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

391936:S7S RS03455
gene id: 391936:S7S_RS03455
uniprot id: A0A0B4XK89
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS08110
gene id: 391936:S7S_RS08110
uniprot id: A0A0B4XP25
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

391936:S7S RS02490
gene id: 391936:S7S_RS02490
uniprot id: A0A0B4XKK6
names: Similarity
messages: Belongs to the YoeB family.

391936:S7S RS01880
gene id: 391936:S7S_RS01880
uniprot id: A0A0B4XFH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

391936:S7S RS11590
gene id: 391936:S7S_RS11590
uniprot id: A0A0B4XKA8
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS05255
gene id: 391936:S7S_RS05255
uniprot id: A0A0B4XLD3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS08955
gene id: 391936:S7S_RS08955
uniprot id: A0A0B4XNY0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

391936:S7S RS00670
gene id: 391936:S7S_RS00670
uniprot id: A0A0B4XJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

391936:S7S RS17680
gene id: 391936:S7S_RS17680
uniprot id: A0A0B4XTX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

391936:S7S RS13935
gene id: 391936:S7S_RS13935
uniprot id: A0A0B4XSC7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

391936:S7S RS11020
gene id: 391936:S7S_RS11020
uniprot id: A0A0B4XPB6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS16665
gene id: 391936:S7S_RS16665
uniprot id: A0A0B4XTW0
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS00170
gene id: 391936:S7S_RS00170
uniprot id: A0A0B4XIT8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS11375
gene id: 391936:S7S_RS11375
uniprot id: A0A0B4XPK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS04915
gene id: 391936:S7S_RS04915
uniprot id: A0A0B4XM27
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

391936:S7S RS04000
gene id: 391936:S7S_RS04000
uniprot id: A0A0B4XGI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

391936:S7S RS13865
gene id: 391936:S7S_RS13865
uniprot id: A0A0B4XRS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

391936:S7S RS09240
gene id: 391936:S7S_RS09240
uniprot id: A0A0B4XM73
names: Similarity
messages: Belongs to the peptidase S41A family.

391936:S7S RS04830
gene id: 391936:S7S_RS04830
uniprot id: A0A0B4XL18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS06660
gene id: 391936:S7S_RS06660
uniprot id: A0A0B4XM45
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS04655
gene id: 391936:S7S_RS04655
uniprot id: A0A0B4XKY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

391936:S7S RS18465
gene id: 391936:S7S_RS18465
uniprot id: A0A0B4XTS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS04780
gene id: 391936:S7S_RS04780
uniprot id: A0A0B4XL08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

391936:S7S RS08680
gene id: 391936:S7S_RS08680
uniprot id: A0A0B4XNT8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS15895
gene id: 391936:S7S_RS15895
uniprot id: A0A0B4XMJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

391936:S7S RS13500
gene id: 391936:S7S_RS13500
uniprot id: A0A0B4XQM5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

391936:S7S RS03215
gene id: 391936:S7S_RS03215
uniprot id: A0A0B4XK54
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

391936:S7S RS00685
gene id: 391936:S7S_RS00685
uniprot id: A0A0B4XHN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

391936:S7S RS12985
gene id: 391936:S7S_RS12985
uniprot id: A0A0B4XL78
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

391936:S7S RS15710
gene id: 391936:S7S_RS15710
uniprot id: A0A0B4XSW5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

391936:S7S RS05730
gene id: 391936:S7S_RS05730
uniprot id: A0A0B4XMK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

391936:S7S RS17035
gene id: 391936:S7S_RS17035
uniprot id: A0A0B4XN44
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

391936:S7S RS04720
gene id: 391936:S7S_RS04720
uniprot id: A0A0B4XLC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

391936:S7S RS17505
gene id: 391936:S7S_RS17505
uniprot id: A0A0B4XTS8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

391936:S7S RS11840
gene id: 391936:S7S_RS11840
uniprot id: A0A0B4XQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

391936:S7S RS16045
gene id: 391936:S7S_RS16045
uniprot id: A0A0B4XML6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS11010
gene id: 391936:S7S_RS11010
uniprot id: A0A0B4XQ79
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

391936:S7S RS16680
gene id: 391936:S7S_RS16680
uniprot id: A0A0B4XSK8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

391936:S7S RS10705
gene id: 391936:S7S_RS10705
uniprot id: A0A0B4XQM3
names: Similarity
messages: Belongs to the HepT RNase toxin family.

391936:S7S RS14895
gene id: 391936:S7S_RS14895
uniprot id: A0A0B4XQ89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

391936:S7S RS03885
gene id: 391936:S7S_RS03885
uniprot id: A0A0B4XKG1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS09305
gene id: 391936:S7S_RS09305
uniprot id: A0A0B4XIY4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

391936:S7S RS13860
gene id: 391936:S7S_RS13860
uniprot id: A0A0B4XSB6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

391936:S7S RS00395
gene id: 391936:S7S_RS00395
uniprot id: A0A0B4XIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

391936:S7S RS00655
gene id: 391936:S7S_RS00655
uniprot id: A0A0B4XIN4
names: Similarity
messages: Belongs to the peptidase M16 family.

391936:S7S RS12405
gene id: 391936:S7S_RS12405
uniprot id: A0A0B4XRJ3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

391936:S7S RS18030
gene id: 391936:S7S_RS18030
uniprot id: A0A0B4XU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

391936:S7S RS11310
gene id: 391936:S7S_RS11310
uniprot id: A0A0B4XQZ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS16015
gene id: 391936:S7S_RS16015
uniprot id: A0A0B4XSZ6
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

391936:S7S RS01710
gene id: 391936:S7S_RS01710
uniprot id: A0A0B4XI66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

391936:S7S RS17695
gene id: 391936:S7S_RS17695
uniprot id: A0A0B4XRW7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

391936:S7S RS04480
gene id: 391936:S7S_RS04480
uniprot id: A0A0B4XKV5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

391936:S7S RS10045
gene id: 391936:S7S_RS10045
uniprot id: A0A0B4XQ63
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

391936:S7S RS15860
gene id: 391936:S7S_RS15860
uniprot id: A0A0B4XTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

391936:S7S RS18215
gene id: 391936:S7S_RS18215
uniprot id: A0A0B4XTM9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS14955
gene id: 391936:S7S_RS14955
uniprot id: A0A0B4XSI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

391936:S7S RS18145
gene id: 391936:S7S_RS18145
uniprot id: A0A0B4XS75
names: Similarity
messages: Belongs to the UPF0235 family.

391936:S7S RS10990
gene id: 391936:S7S_RS10990
uniprot id: A0A0B4XJZ6
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS02235
gene id: 391936:S7S_RS02235
uniprot id: A0A0B4XJK1
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

391936:S7S RS11675
gene id: 391936:S7S_RS11675
uniprot id: A0A0B4XNP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

391936:S7S RS08640
gene id: 391936:S7S_RS08640
uniprot id: A0A0B4XN28
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

391936:S7S RS12030
gene id: 391936:S7S_RS12030
uniprot id: A0A0B4XRC5
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS12970
gene id: 391936:S7S_RS12970
uniprot id: A0A0B4XPE5
names: Similarity
messages: Belongs to the UPF0145 family.

391936:S7S RS05280
gene id: 391936:S7S_RS05280
uniprot id: A0A0B4XLD5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

391936:S7S RS11560
gene id: 391936:S7S_RS11560
uniprot id: A0A0B4XKA3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

391936:S7S RS07115
gene id: 391936:S7S_RS07115
uniprot id: A0A0B4XNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS05800
gene id: 391936:S7S_RS05800
uniprot id: A0A0B4XMM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

391936:S7S RS09460
gene id: 391936:S7S_RS09460
uniprot id: A0A0B4XJ19
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

391936:S7S RS02240
gene id: 391936:S7S_RS02240
uniprot id: A0A0B4XIH6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS04355
gene id: 391936:S7S_RS04355
uniprot id: A0A0B4XKS9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS15760
gene id: 391936:S7S_RS15760
uniprot id: A0A0B4XSX0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

391936:S7S RS07610
gene id: 391936:S7S_RS07610
uniprot id: A0A0B4XMQ3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

391936:S7S RS10260
gene id: 391936:S7S_RS10260
uniprot id: A0A0B4XNY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

391936:S7S RS09165
gene id: 391936:S7S_RS09165
uniprot id: A0A0B4XM63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

391936:S7S RS01105
gene id: 391936:S7S_RS01105
uniprot id: A0A0B4XIX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

391936:S7S RS12070
gene id: 391936:S7S_RS12070
uniprot id: A0A0B4XPW9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

391936:S7S RS09670
gene id: 391936:S7S_RS09670
uniprot id: A0A0B4XMI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

391936:S7S RS07420
gene id: 391936:S7S_RS07420
uniprot id: A0A0B4XNM5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

391936:S7S RS06010
gene id: 391936:S7S_RS06010
uniprot id: A0A0B4XM40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

391936:S7S RS01675
gene id: 391936:S7S_RS01675
uniprot id: A0A0B4XFD5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

391936:S7S RS18330
gene id: 391936:S7S_RS18330
uniprot id: A0A0B4XUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

391936:S7S RS01460
gene id: 391936:S7S_RS01460
uniprot id: A0A0B4XJ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

391936:S7S RS17205
gene id: 391936:S7S_RS17205
uniprot id: A0A0B4XN88
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

391936:S7S RS18340
gene id: 391936:S7S_RS18340
uniprot id: A0A0B4XTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

391936:S7S RS00245
gene id: 391936:S7S_RS00245
uniprot id: A0A0B4XIU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

391936:S7S RS03025
gene id: 391936:S7S_RS03025
uniprot id: A0A0B4XKZ8
names: Similarity
messages: Belongs to the GSP N family.

391936:S7S RS19635
gene id: 391936:S7S_RS19635
uniprot id: A0A0B4XRE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

391936:S7S RS04850
gene id: 391936:S7S_RS04850
uniprot id: A0A0B4XGY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

391936:S7S RS10435
gene id: 391936:S7S_RS10435
uniprot id: A0A0B4XPZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

391936:S7S RS02095
gene id: 391936:S7S_RS02095
uniprot id: A0A0B4XKA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

391936:S7S RS04460
gene id: 391936:S7S_RS04460
uniprot id: A0A0B4XJR1
names: Similarity
messages: Belongs to the PhzF family.

391936:S7S RS11265
gene id: 391936:S7S_RS11265
uniprot id: A0A0B4XQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

391936:S7S RS15430
gene id: 391936:S7S_RS15430
uniprot id: A0A0B4XT60
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS16210
gene id: 391936:S7S_RS16210
uniprot id: A0A0B4XTK8
names: PTM
messages: Binds 1 heme group per subunit.

391936:S7S RS03610
gene id: 391936:S7S_RS03610
uniprot id: A0A0B4XKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

391936:S7S RS02905
gene id: 391936:S7S_RS02905
uniprot id: A0A0B4XKX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

391936:S7S RS13270
gene id: 391936:S7S_RS13270
uniprot id: A0A0B4XQI8
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

391936:S7S RS09600
gene id: 391936:S7S_RS09600
uniprot id: A0A0B4XPY9
names: Similarity
messages: Belongs to the PrpD family.

391936:S7S RS12050
gene id: 391936:S7S_RS12050
uniprot id: A0A0B4XNV7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

391936:S7S RS16235
gene id: 391936:S7S_RS16235
uniprot id: A0A0B4XTL4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS03005
gene id: 391936:S7S_RS03005
uniprot id: A0A0B4XKH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

391936:S7S RS04395
gene id: 391936:S7S_RS04395
uniprot id: A0A0B4XL44
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

391936:S7S RS09935
gene id: 391936:S7S_RS09935
uniprot id: A0A0B4XPL9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

391936:S7S RS16925
gene id: 391936:S7S_RS16925
uniprot id: A0A0B4XRF8
names: Cofactor
messages: Can also use Mn(2+) ion.

391936:S7S RS04495
gene id: 391936:S7S_RS04495
uniprot id: A0A0B4XL69
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

391936:S7S RS09550
gene id: 391936:S7S_RS09550
uniprot id: A0A0B4XPX3
names: Similarity
messages: Belongs to the glutamate synthase family.

391936:S7S RS13655
gene id: 391936:S7S_RS13655
uniprot id: A0A0B4XPL1
names: Similarity
messages: Belongs to the PhoH family.

391936:S7S RS13460
gene id: 391936:S7S_RS13460
uniprot id: A0A0B4XS53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

391936:S7S RS02930
gene id: 391936:S7S_RS02930
uniprot id: A0A0B4XKX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

391936:S7S RS11805
gene id: 391936:S7S_RS11805
uniprot id: A0A0B4XNR3
names: Similarity
messages: Belongs to the GST superfamily.

391936:S7S RS09715
gene id: 391936:S7S_RS09715
uniprot id: A0A0B4XNJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

391936:S7S RS07370
gene id: 391936:S7S_RS07370
uniprot id: A0A0B4XNL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

391936:S7S RS00640
gene id: 391936:S7S_RS00640
uniprot id: A0A0B4XJG0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

391936:S7S RS17815
gene id: 391936:S7S_RS17815
uniprot id: A0A0B4XTF7
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

391936:S7S RS10775
gene id: 391936:S7S_RS10775
uniprot id: A0A0B4XN98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

391936:S7S RS11340
gene id: 391936:S7S_RS11340
uniprot id: A0A0B4XQC0
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

391936:S7S RS10125
gene id: 391936:S7S_RS10125
uniprot id: A0A0B4XPS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS04100
gene id: 391936:S7S_RS04100
uniprot id: A0A0B4XGK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

391936:S7S RS08020
gene id: 391936:S7S_RS08020
uniprot id: A0A0B4XIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS13390
gene id: 391936:S7S_RS13390
uniprot id: A0A0B4XLD6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

391936:S7S RS06535
gene id: 391936:S7S_RS06535
uniprot id: A0A0B4XN26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

391936:S7S RS10520
gene id: 391936:S7S_RS10520
uniprot id: A0A0B4XQJ3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

391936:S7S RS13785
gene id: 391936:S7S_RS13785
uniprot id: A0A0B4XSA4
names: Similarity
messages: Belongs to the Gfa family.

391936:S7S RS07770
gene id: 391936:S7S_RS07770
uniprot id: A0A0B4XLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

391936:S7S RS12470
gene id: 391936:S7S_RS12470
uniprot id: A0A0B4XQ60
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

391936:S7S RS16550
gene id: 391936:S7S_RS16550
uniprot id: A0A0B4XR83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

391936:S7S RS05940
gene id: 391936:S7S_RS05940
uniprot id: A0A0B4XLN4
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS04360
gene id: 391936:S7S_RS04360
uniprot id: A0A0B4XJP7
names: Similarity
messages: Belongs to the pirin family.

391936:S7S RS00750
gene id: 391936:S7S_RS00750
uniprot id: A0A0B4XEY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS10650
gene id: 391936:S7S_RS10650
uniprot id: A0A0B4XN79
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

391936:S7S RS00110
gene id: 391936:S7S_RS00110
uniprot id: A0A0B4XHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

391936:S7S RS06950
gene id: 391936:S7S_RS06950
uniprot id: A0A0B4XI11
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

391936:S7S RS03305
gene id: 391936:S7S_RS03305
uniprot id: A0A0B4XJ59
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

391936:S7S RS01445
gene id: 391936:S7S_RS01445
uniprot id: A0A0B4XJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

391936:S7S RS00330
gene id: 391936:S7S_RS00330
uniprot id: A0A0B4XIG6
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS16915
gene id: 391936:S7S_RS16915
uniprot id: A0A0B4XU15
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

391936:S7S RS15170
gene id: 391936:S7S_RS15170
uniprot id: A0A0B4XQF8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

391936:S7S RS08160
gene id: 391936:S7S_RS08160
uniprot id: A0A0B4XP33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS12340
gene id: 391936:S7S_RS12340
uniprot id: A0A0B4XKR2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

391936:S7S RS03245
gene id: 391936:S7S_RS03245
uniprot id: A0A0B4XJ46
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

391936:S7S RS00855
gene id: 391936:S7S_RS00855
uniprot id: A0A0B4XEZ9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

391936:S7S RS09750
gene id: 391936:S7S_RS09750
uniprot id: A0A0B4XQ14
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

391936:S7S RS04255
gene id: 391936:S7S_RS04255
uniprot id: A0A0B4XKQ7
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

391936:S7S RS06230
gene id: 391936:S7S_RS06230
uniprot id: A0A0B4XMV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS05075
gene id: 391936:S7S_RS05075
uniprot id: A0A0B4XH30
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

391936:S7S RS14140
gene id: 391936:S7S_RS14140
uniprot id: A0A0B4XRY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

391936:S7S RS11410
gene id: 391936:S7S_RS11410
uniprot id: A0A0B4XR17
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS13695
gene id: 391936:S7S_RS13695
uniprot id: A0A0B4XLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

391936:S7S RS01490
gene id: 391936:S7S_RS01490
uniprot id: A0A0B4XI22
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

391936:S7S RS04855
gene id: 391936:S7S_RS04855
uniprot id: A0A0B4XL23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

391936:S7S RS03700
gene id: 391936:S7S_RS03700
uniprot id: A0A0B4XKR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

391936:S7S RS05295
gene id: 391936:S7S_RS05295
uniprot id: A0A0B4XLS4
names: Similarity
messages: Belongs to the thioesterase family.

391936:S7S RS08480
gene id: 391936:S7S_RS08480
uniprot id: A0A0B4XNQ2
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS06325
gene id: 391936:S7S_RS06325
uniprot id: A0A0B4XKP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

391936:S7S RS17705
gene id: 391936:S7S_RS17705
uniprot id: A0A0B4XTZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

391936:S7S RS08940
gene id: 391936:S7S_RS08940
uniprot id: A0A0B4XN63
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

391936:S7S RS09570
gene id: 391936:S7S_RS09570
uniprot id: A0A0B4XME9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

391936:S7S RS01620
gene id: 391936:S7S_RS01620
uniprot id: A0A0B4XJK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

391936:S7S RS00420
gene id: 391936:S7S_RS00420
uniprot id: A0A0B4XIX3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

391936:S7S RS08275
gene id: 391936:S7S_RS08275
uniprot id: A0A0B4XMZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

391936:S7S RS16090
gene id: 391936:S7S_RS16090
uniprot id: A0A0B4XT03
names: Similarity
messages: Belongs to the Gfa family.

391936:S7S RS05440
gene id: 391936:S7S_RS05440
uniprot id: A0A0B4XME8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

391936:S7S RS09135
gene id: 391936:S7S_RS09135
uniprot id: A0A0B4XN89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS10570
gene id: 391936:S7S_RS10570
uniprot id: A0A0B4XQK0
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

391936:S7S RS01810
gene id: 391936:S7S_RS01810
uniprot id: A0A0B4XI86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS04385
gene id: 391936:S7S_RS04385
uniprot id: A0A0B4XJQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

391936:S7S RS02330
gene id: 391936:S7S_RS02330
uniprot id: A0A0B4XFR9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

391936:S7S RS00415
gene id: 391936:S7S_RS00415
uniprot id: A0A0B4XJC1
names: Similarity
messages: Belongs to the UPF0758 family.

391936:S7S RS03970
gene id: 391936:S7S_RS03970
uniprot id: A0A0B4XKV2
names: Similarity
messages: Belongs to the MipA/OmpV family.

391936:S7S RS17660
gene id: 391936:S7S_RS17660
uniprot id: A0A0B4XNI2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

391936:S7S RS11850
gene id: 391936:S7S_RS11850
uniprot id: A0A0B4XPS8
names: Similarity
messages: Belongs to the peptidase C56 family.

391936:S7S RS13085
gene id: 391936:S7S_RS13085
uniprot id: A0A0B4XL88
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS17465
gene id: 391936:S7S_RS17465
uniprot id: A0A0B4XT59
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS10380
gene id: 391936:S7S_RS10380
uniprot id: A0A0B4XQH4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

391936:S7S RS11950
gene id: 391936:S7S_RS11950
uniprot id: A0A0B4XPU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

391936:S7S RS09045
gene id: 391936:S7S_RS09045
uniprot id: A0A0B4XM50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

391936:S7S RS01360
gene id: 391936:S7S_RS01360
uniprot id: A0A0B4XJU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

391936:S7S RS06135
gene id: 391936:S7S_RS06135
uniprot id: A0A0B4XM67
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

391936:S7S RS12350
gene id: 391936:S7S_RS12350
uniprot id: A0A0B4XP27
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

391936:S7S RS12520
gene id: 391936:S7S_RS12520
uniprot id: A0A0B4XQ68
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

391936:S7S RS08045
gene id: 391936:S7S_RS08045
uniprot id: A0A0B4XIH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

391936:S7S RS10285
gene id: 391936:S7S_RS10285
uniprot id: A0A0B4XNY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

391936:S7S RS02975
gene id: 391936:S7S_RS02975
uniprot id: A0A0B4XKZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

391936:S7S RS16265
gene id: 391936:S7S_RS16265
uniprot id: A0A0B4XT23
names: Similarity
messages: Belongs to the peptidase C59 family.

391936:S7S RS08755
gene id: 391936:S7S_RS08755
uniprot id: A0A0B4XNU7
names: Similarity
messages: Belongs to the BolA/IbaG family.

391936:S7S RS06215
gene id: 391936:S7S_RS06215
uniprot id: A0A0B4XHL0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS15000
gene id: 391936:S7S_RS15000
uniprot id: A0A0B4XSW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

391936:S7S RS08030
gene id: 391936:S7S_RS08030
uniprot id: A0A0B4XLM4
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

391936:S7S RS14970
gene id: 391936:S7S_RS14970
uniprot id: A0A0B4XQA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

391936:S7S RS05565
gene id: 391936:S7S_RS05565
uniprot id: A0A0B4XKB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

391936:S7S RS10005
gene id: 391936:S7S_RS10005
uniprot id: A0A0B4XJE2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

391936:S7S RS18150
gene id: 391936:S7S_RS18150
uniprot id: A0A0B4XUU7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

391936:S7S RS02050
gene id: 391936:S7S_RS02050
uniprot id: A0A0B4XJU6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

391936:S7S RS15850
gene id: 391936:S7S_RS15850
uniprot id: A0A0B4XS19
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

391936:S7S RS14315
gene id: 391936:S7S_RS14315
uniprot id: A0A0B4XLW5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS18120
gene id: 391936:S7S_RS18120
uniprot id: A0A0B4XS73
names: Similarity
messages: Belongs to the GSP E family.

391936:S7S RS01255
gene id: 391936:S7S_RS01255
uniprot id: A0A0B4XJ02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

391936:S7S RS18635
gene id: 391936:S7S_RS18635
uniprot id: A0A0B4XUF8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS10490
gene id: 391936:S7S_RS10490
uniprot id: A0A0B4XQI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

391936:S7S RS13980
gene id: 391936:S7S_RS13980
uniprot id: A0A0B4XPR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

391936:S7S RS04335
gene id: 391936:S7S_RS04335
uniprot id: A0A0B4XJP4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

391936:S7S RS08870
gene id: 391936:S7S_RS08870
uniprot id: A0A0B4XM17
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS09615
gene id: 391936:S7S_RS09615
uniprot id: A0A0B4XNH8
names: Similarity
messages: Belongs to the citrate synthase family.

391936:S7S RS06910
gene id: 391936:S7S_RS06910
uniprot id: A0A0B4XMA3
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS09475
gene id: 391936:S7S_RS09475
uniprot id: A0A0B4XPV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

391936:S7S RS01100
gene id: 391936:S7S_RS01100
uniprot id: A0A0B4XF42
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

391936:S7S RS02885
gene id: 391936:S7S_RS02885
uniprot id: A0A0B4XKF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

391936:S7S RS05245
gene id: 391936:S7S_RS05245
uniprot id: A0A0B4XLR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS00660
gene id: 391936:S7S_RS00660
uniprot id: A0A0B4XHM7
names: Similarity
messages: Belongs to the peptidase M16 family.

391936:S7S RS11250
gene id: 391936:S7S_RS11250
uniprot id: A0A0B4XPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

391936:S7S RS15530
gene id: 391936:S7S_RS15530
uniprot id: A0A0B4XT75
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS17935
gene id: 391936:S7S_RS17935
uniprot id: A0A0B4XNR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS02375
gene id: 391936:S7S_RS02375
uniprot id: A0A0B4XFT0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

391936:S7S RS13640
gene id: 391936:S7S_RS13640
uniprot id: A0A0B4XRP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

391936:S7S RS09900
gene id: 391936:S7S_RS09900
uniprot id: A0A0B4XQ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

391936:S7S RS15650
gene id: 391936:S7S_RS15650
uniprot id: A0A0B4XQS4
names: Similarity
messages: Belongs to the UPF0502 family.

391936:S7S RS14045
gene id: 391936:S7S_RS14045
uniprot id: A0A0B4XLP6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

391936:S7S RS01210
gene id: 391936:S7S_RS01210
uniprot id: A0A0B4XHW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

391936:S7S RS18035
gene id: 391936:S7S_RS18035
uniprot id: A0A0B4XNT0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

391936:S7S RS02105
gene id: 391936:S7S_RS02105
uniprot id: A0A0B4XFM4
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

391936:S7S RS12930
gene id: 391936:S7S_RS12930
uniprot id: A0A0B4XRE7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS08550
gene id: 391936:S7S_RS08550
uniprot id: A0A0B4XPA7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

391936:S7S RS16635
gene id: 391936:S7S_RS16635
uniprot id: A0A0B4XR97
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS09440
gene id: 391936:S7S_RS09440
uniprot id: A0A0B4XNF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

391936:S7S RS08450
gene id: 391936:S7S_RS08450
uniprot id: A0A0B4XP87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

391936:S7S RS12135
gene id: 391936:S7S_RS12135
uniprot id: A0A0B4XQV7
names: Similarity
messages: Belongs to the Skp family.

391936:S7S RS18305
gene id: 391936:S7S_RS18305
uniprot id: A0A0B4XUA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

391936:S7S RS02175
gene id: 391936:S7S_RS02175
uniprot id: A0A0B4XJW8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

391936:S7S RS04585
gene id: 391936:S7S_RS04585
uniprot id: A0A0B4XJT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

391936:S7S RS01965
gene id: 391936:S7S_RS01965
uniprot id: A0A0B4XIB1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS03325
gene id: 391936:S7S_RS03325
uniprot id: A0A0B4XK69
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

391936:S7S RS13730
gene id: 391936:S7S_RS13730
uniprot id: A0A0B4XPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

391936:S7S RS05855
gene id: 391936:S7S_RS05855
uniprot id: A0A0B4XM10
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

391936:S7S RS14885
gene id: 391936:S7S_RS14885
uniprot id: A0A0B4XM60
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

391936:S7S RS15915
gene id: 391936:S7S_RS15915
uniprot id: A0A0B4XSY4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

391936:S7S RS00105
gene id: 391936:S7S_RS00105
uniprot id: A0A0B4XIC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS16935
gene id: 391936:S7S_RS16935
uniprot id: A0A0B4XTE6
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

391936:S7S RS04730
gene id: 391936:S7S_RS04730
uniprot id: A0A0B4XL01
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

391936:S7S RS09850
gene id: 391936:S7S_RS09850
uniprot id: A0A0B4XQ31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

391936:S7S RS10555
gene id: 391936:S7S_RS10555
uniprot id: A0A0B4XJS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS09025
gene id: 391936:S7S_RS09025
uniprot id: A0A0B4XPM2
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

391936:S7S RS07925
gene id: 391936:S7S_RS07925
uniprot id: A0A0B4XNZ5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

391936:S7S RS06445
gene id: 391936:S7S_RS06445
uniprot id: A0A0B4XHQ3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

391936:S7S RS00675
gene id: 391936:S7S_RS00675
uniprot id: A0A0B4XEW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

391936:S7S RS09800
gene id: 391936:S7S_RS09800
uniprot id: A0A0B4XQ24
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

391936:S7S RS10750
gene id: 391936:S7S_RS10750
uniprot id: A0A0B4XN94
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

391936:S7S RS04370
gene id: 391936:S7S_RS04370
uniprot id: A0A0B4XL38
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

391936:S7S RS10295
gene id: 391936:S7S_RS10295
uniprot id: A0A0B4XQF7
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS17885
gene id: 391936:S7S_RS17885
uniprot id: A0A0B4XNQ4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

391936:S7S RS05050
gene id: 391936:S7S_RS05050
uniprot id: A0A0B4XH25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

391936:S7S RS02955
gene id: 391936:S7S_RS02955
uniprot id: A0A0B4XKY3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

391936:S7S RS13120
gene id: 391936:S7S_RS13120
uniprot id: A0A0B4XQG5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

391936:S7S RS15705
gene id: 391936:S7S_RS15705
uniprot id: A0A0B4XTA6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

391936:S7S RS00970
gene id: 391936:S7S_RS00970
uniprot id: A0A0B4XJ76
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

391936:S7S RS09985
gene id: 391936:S7S_RS09985
uniprot id: A0A0B4XNP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

391936:S7S RS15585
gene id: 391936:S7S_RS15585
uniprot id: A0A0B4XSV5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

391936:S7S RS00585
gene id: 391936:S7S_RS00585
uniprot id: A0A0B4XHL2
names: Similarity
messages: Belongs to the alphaproteobacteria porin family.

391936:S7S RS11390
gene id: 391936:S7S_RS11390
uniprot id: A0A0B4XQD1
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

391936:S7S RS10510
gene id: 391936:S7S_RS10510
uniprot id: A0A0B4XP18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

391936:S7S RS16240
gene id: 391936:S7S_RS16240
uniprot id: A0A0B4XT20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS17135
gene id: 391936:S7S_RS17135
uniprot id: A0A0B4XSY5
names: Similarity
messages: Belongs to the P(II) protein family.

391936:S7S RS17270
gene id: 391936:S7S_RS17270
uniprot id: A0A0B4XUA2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

391936:S7S RS07300
gene id: 391936:S7S_RS07300
uniprot id: A0A0B4XMY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS08785
gene id: 391936:S7S_RS08785
uniprot id: A0A0B4XIP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

391936:S7S RS03670
gene id: 391936:S7S_RS03670
uniprot id: A0A0B4XL93
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

391936:S7S RS09970
gene id: 391936:S7S_RS09970
uniprot id: A0A0B4XQ48
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

391936:S7S RS05740
gene id: 391936:S7S_RS05740
uniprot id: A0A0B4XHE4
names: Function
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

391936:S7S RS02310
gene id: 391936:S7S_RS02310
uniprot id: A0A0B4XJL6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

391936:S7S RS15685
gene id: 391936:S7S_RS15685
uniprot id: A0A0B4XSW3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

391936:S7S RS04770
gene id: 391936:S7S_RS04770
uniprot id: A0A0B4XLD7
names: Similarity
messages: Belongs to the UPF0102 family.

391936:S7S RS01650
gene id: 391936:S7S_RS01650
uniprot id: A0A0B4XFD1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

391936:S7S RS07665
gene id: 391936:S7S_RS07665
uniprot id: A0A0B4XMT6
names: Similarity
messages: Belongs to the neutral ceramidase family.

391936:S7S RS13895
gene id: 391936:S7S_RS13895
uniprot id: A0A0B4XLL9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS05540
gene id: 391936:S7S_RS05540
uniprot id: A0A0B4XKB2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

391936:S7S RS10050
gene id: 391936:S7S_RS10050
uniprot id: A0A0B4XPP7
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS02435
gene id: 391936:S7S_RS02435
uniprot id: A0A0B4XIN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

391936:S7S RS03020
gene id: 391936:S7S_RS03020
uniprot id: A0A0B4XJ04
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

391936:S7S RS11610
gene id: 391936:S7S_RS11610
uniprot id: A0A0B4XQI2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

391936:S7S RS00315
gene id: 391936:S7S_RS00315
uniprot id: A0A0B4XPU9
names: Similarity
messages: Belongs to the transposase 8 family.

391936:S7S RS08190
gene id: 391936:S7S_RS08190
uniprot id: A0A0B4XNK5
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

391936:S7S RS13255
gene id: 391936:S7S_RS13255
uniprot id: A0A0B4XS25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

391936:S7S RS10225
gene id: 391936:S7S_RS10225
uniprot id: A0A0B4XPX2
names: Similarity
messages: Belongs to the YkuD family.

391936:S7S RS06285
gene id: 391936:S7S_RS06285
uniprot id: A0A0B4XM90
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

391936:S7S RS10055
gene id: 391936:S7S_RS10055
uniprot id: A0A0B4XJF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

391936:S7S RS08925
gene id: 391936:S7S_RS08925
uniprot id: A0A0B4XPJ6
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

391936:S7S RS08260
gene id: 391936:S7S_RS08260
uniprot id: A0A0B4XP53
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS00380
gene id: 391936:S7S_RS00380
uniprot id: A0A0B4XIH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

391936:S7S RS02880
gene id: 391936:S7S_RS02880
uniprot id: A0A0B4XKW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

391936:S7S RS01585
gene id: 391936:S7S_RS01585
uniprot id: A0A0B4XI41
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS16125
gene id: 391936:S7S_RS16125
uniprot id: A0A0B4XS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

391936:S7S RS14640
gene id: 391936:S7S_RS14640
uniprot id: A0A0B4XM22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

391936:S7S RS07190
gene id: 391936:S7S_RS07190
uniprot id: A0A0B4XL52
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS14705
gene id: 391936:S7S_RS14705
uniprot id: A0A0B4XSD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

391936:S7S RS05475
gene id: 391936:S7S_RS05475
uniprot id: A0A0B4XHA3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

391936:S7S RS18135
gene id: 391936:S7S_RS18135
uniprot id: A0A0B4XNU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

391936:S7S RS11025
gene id: 391936:S7S_RS11025
uniprot id: A0A0B4XNE0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

391936:S7S RS06350
gene id: 391936:S7S_RS06350
uniprot id: A0A0B4XKQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS07255
gene id: 391936:S7S_RS07255
uniprot id: A0A0B4XI67
names: Similarity
messages: Belongs to the SELO family.

391936:S7S RS08760
gene id: 391936:S7S_RS08760
uniprot id: A0A0B4XIP4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

391936:S7S RS08775
gene id: 391936:S7S_RS08775
uniprot id: A0A0B4XPF6
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS11700
gene id: 391936:S7S_RS11700
uniprot id: A0A0B4XNP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS02305
gene id: 391936:S7S_RS02305
uniprot id: A0A0B4XFR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

391936:S7S RS01725
gene id: 391936:S7S_RS01725
uniprot id: A0A0B4XFE2
names: Similarity
messages: Belongs to the glutamate synthase family.

391936:S7S RS00445
gene id: 391936:S7S_RS00445
uniprot id: A0A0B4XIX6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

391936:S7S RS17790
gene id: 391936:S7S_RS17790
uniprot id: A0A0B4XTF4
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

391936:S7S RS14810
gene id: 391936:S7S_RS14810
uniprot id: A0A0B4XM47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

391936:S7S RS14215
gene id: 391936:S7S_RS14215
uniprot id: A0A0B4XRZ9
names: Similarity
messages: Belongs to the YciI family.

391936:S7S RS16360
gene id: 391936:S7S_RS16360
uniprot id: A0A0B4XR47
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

391936:S7S RS01125
gene id: 391936:S7S_RS01125
uniprot id: A0A0B4XF45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

391936:S7S RS07095
gene id: 391936:S7S_RS07095
uniprot id: A0A0B4XMT0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS00960
gene id: 391936:S7S_RS00960
uniprot id: A0A0B4XHS3
names: Similarity
messages: Belongs to the peptidase M24B family.

391936:S7S RS14770
gene id: 391936:S7S_RS14770
uniprot id: A0A0B4XQ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

391936:S7S RS08805
gene id: 391936:S7S_RS08805
uniprot id: A0A0B4XNV5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

391936:S7S RS18125
gene id: 391936:S7S_RS18125
uniprot id: A0A0B4XUU4
names: Similarity
messages: Belongs to the GSP E family.

391936:S7S RS04205
gene id: 391936:S7S_RS04205
uniprot id: A0A0B4XKP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

391936:S7S RS07530
gene id: 391936:S7S_RS07530
uniprot id: A0A0B4XIA3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

391936:S7S RS11650
gene id: 391936:S7S_RS11650
uniprot id: A0A0B4XNN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

391936:S7S RS03805
gene id: 391936:S7S_RS03805
uniprot id: A0A0B4XGE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS04910
gene id: 391936:S7S_RS04910
uniprot id: A0A0B4XJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

391936:S7S RS16980
gene id: 391936:S7S_RS16980
uniprot id: A0A0B4XTF6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

391936:S7S RS17605
gene id: 391936:S7S_RS17605
uniprot id: A0A0B4XTV2
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS05175
gene id: 391936:S7S_RS05175
uniprot id: A0A0B4XH66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

391936:S7S RS02605
gene id: 391936:S7S_RS02605
uniprot id: A0A0B4XIU5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS05690
gene id: 391936:S7S_RS05690
uniprot id: A0A0B4XHD6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS06175
gene id: 391936:S7S_RS06175
uniprot id: A0A0B4XKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

391936:S7S RS06290
gene id: 391936:S7S_RS06290
uniprot id: A0A0B4XHM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS13375
gene id: 391936:S7S_RS13375
uniprot id: A0A0B4XPI5
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

391936:S7S RS13870
gene id: 391936:S7S_RS13870
uniprot id: A0A0B4XLL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

391936:S7S RS03590
gene id: 391936:S7S_RS03590
uniprot id: A0A0B4XJB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

391936:S7S RS00375
gene id: 391936:S7S_RS00375
uniprot id: A0A0B4XER4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

391936:S7S RS05015
gene id: 391936:S7S_RS05015
uniprot id: A0A0B4XM57
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

391936:S7S RS07260
gene id: 391936:S7S_RS07260
uniprot id: A0A0B4XMI8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

391936:S7S RS10180
gene id: 391936:S7S_RS10180
uniprot id: A0A0B4XJI2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

391936:S7S RS12075
gene id: 391936:S7S_RS12075
uniprot id: A0A0B4XNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

391936:S7S RS09200
gene id: 391936:S7S_RS09200
uniprot id: A0A0B4XP31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

391936:S7S RS03550
gene id: 391936:S7S_RS03550
uniprot id: A0A0B4XGA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

391936:S7S RS17915
gene id: 391936:S7S_RS17915
uniprot id: A0A0B4XTH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

391936:S7S RS15105
gene id: 391936:S7S_RS15105
uniprot id: A0A0B4XM93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

391936:S7S RS05430
gene id: 391936:S7S_RS05430
uniprot id: A0A0B4XLF4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

391936:S7S RS14385
gene id: 391936:S7S_RS14385
uniprot id: A0A0B4XS45
names: Similarity
messages: Belongs to the type IA topoisomerase family.

391936:S7S RS16030
gene id: 391936:S7S_RS16030
uniprot id: A0A0B4XQY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

391936:S7S RS09610
gene id: 391936:S7S_RS09610
uniprot id: A0A0B4XJ49
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

391936:S7S RS04220
gene id: 391936:S7S_RS04220
uniprot id: A0A0B4XL09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

391936:S7S RS08995
gene id: 391936:S7S_RS08995
uniprot id: A0A0B4XM43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

391936:S7S RS08165
gene id: 391936:S7S_RS08165
uniprot id: A0A0B4XNK0
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS01615
gene id: 391936:S7S_RS01615
uniprot id: A0A0B4XJZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

391936:S7S RS13880
gene id: 391936:S7S_RS13880
uniprot id: A0A0B4XPP9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

391936:S7S RS17225
gene id: 391936:S7S_RS17225
uniprot id: A0A0B4XTK5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

391936:S7S RS09925
gene id: 391936:S7S_RS09925
uniprot id: A0A0B4XMQ4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

391936:S7S RS01220
gene id: 391936:S7S_RS01220
uniprot id: A0A0B4XJC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS11075
gene id: 391936:S7S_RS11075
uniprot id: A0A0B4XNE7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

391936:S7S RS00860
gene id: 391936:S7S_RS00860
uniprot id: A0A0B4XIS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

391936:S7S RS16645
gene id: 391936:S7S_RS16645
uniprot id: A0A0B4XT84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

391936:S7S RS03070
gene id: 391936:S7S_RS03070
uniprot id: A0A0B4XJ13
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

391936:S7S RS02190
gene id: 391936:S7S_RS02190
uniprot id: A0A0B4XIG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

391936:S7S RS16840
gene id: 391936:S7S_RS16840
uniprot id: A0A0B4XTZ7
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

391936:S7S RS05505
gene id: 391936:S7S_RS05505
uniprot id: A0A0B4XPU9
names: Similarity
messages: Belongs to the transposase 8 family.

391936:S7S RS04110
gene id: 391936:S7S_RS04110
uniprot id: A0A0B4XJL4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

391936:S7S RS14610
gene id: 391936:S7S_RS14610
uniprot id: A0A0B4XSA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

391936:S7S RS01605
gene id: 391936:S7S_RS01605
uniprot id: A0A0B4XJ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

391936:S7S RS05780
gene id: 391936:S7S_RS05780
uniprot id: A0A0B4XLZ6
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS14875
gene id: 391936:S7S_RS14875
uniprot id: A0A0B4XSS8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

391936:S7S RS02185
gene id: 391936:S7S_RS02185
uniprot id: A0A0B4XJJ2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

391936:S7S RS15665
gene id: 391936:S7S_RS15665
uniprot id: A0A0B4XMH1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

391936:S7S RS07725
gene id: 391936:S7S_RS07725
uniprot id: A0A0B4XNW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

391936:S7S RS06340
gene id: 391936:S7S_RS06340
uniprot id: A0A0B4XHN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

391936:S7S RS10915
gene id: 391936:S7S_RS10915
uniprot id: A0A0B4XJY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

391936:S7S RS15090
gene id: 391936:S7S_RS15090
uniprot id: A0A0B4XQD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

391936:S7S RS00280
gene id: 391936:S7S_RS00280
uniprot id: A0A0B4XIF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

391936:S7S RS16670
gene id: 391936:S7S_RS16670
uniprot id: A0A0B4XT91
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS10060
gene id: 391936:S7S_RS10060
uniprot id: A0A0B4XNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

391936:S7S RS12005
gene id: 391936:S7S_RS12005
uniprot id: A0A0B4XNU8
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

391936:S7S RS02215
gene id: 391936:S7S_RS02215
uniprot id: A0A0B4XIG9
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

391936:S7S RS18445
gene id: 391936:S7S_RS18445
uniprot id: A0A0B4XSB5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS05180
gene id: 391936:S7S_RS05180
uniprot id: A0A0B4XLC6
names: Similarity
messages: Belongs to the YjdM family.

391936:S7S RS15495
gene id: 391936:S7S_RS15495
uniprot id: A0A0B4XRW1
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

391936:S7S RS00165
gene id: 391936:S7S_RS00165
uniprot id: A0A0B4XJ96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

391936:S7S RS08070
gene id: 391936:S7S_RS08070
uniprot id: A0A0B4XIH3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

391936:S7S RS09255
gene id: 391936:S7S_RS09255
uniprot id: A0A0B4XIX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates influx of magnesium ions.
messages: Membrane

391936:S7S RS15805
gene id: 391936:S7S_RS15805
uniprot id: A0A0B4XQU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

391936:S7S RS18505
gene id: 391936:S7S_RS18505
uniprot id: A0A0B4XUD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

391936:S7S RS05820
gene id: 391936:S7S_RS05820
uniprot id: A0A0B4XKG3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

391936:S7S RS02365
gene id: 391936:S7S_RS02365
uniprot id: A0A0B4XIL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

391936:S7S RS04155
gene id: 391936:S7S_RS04155
uniprot id: A0A0B4XKN2
names: Similarity
messages: Belongs to the Fur family.

391936:S7S RS12355
gene id: 391936:S7S_RS12355
uniprot id: A0A0B4XRI2
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

391936:S7S RS02945
gene id: 391936:S7S_RS02945
uniprot id: A0A0B4XK19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

391936:S7S RS06295
gene id: 391936:S7S_RS06295
uniprot id: A0A0B4XLW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

391936:S7S RS10985
gene id: 391936:S7S_RS10985
uniprot id: A0A0B4XQ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

391936:S7S RS01435
gene id: 391936:S7S_RS01435
uniprot id: A0A0B4XI13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

391936:S7S RS04595
gene id: 391936:S7S_RS04595
uniprot id: A0A0B4XL95
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS14865
gene id: 391936:S7S_RS14865
uniprot id: A0A0B4XRG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

391936:S7S RS16850
gene id: 391936:S7S_RS16850
uniprot id: A0A0B4XMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

391936:S7S RS16715
gene id: 391936:S7S_RS16715
uniprot id: A0A0B4XTW9
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

391936:S7S RS02590
gene id: 391936:S7S_RS02590
uniprot id: A0A0B4XKA1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

391936:S7S RS11990
gene id: 391936:S7S_RS11990
uniprot id: A0A0B4XQS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

391936:S7S RS04875
gene id: 391936:S7S_RS04875
uniprot id: A0A0B4XGZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

391936:S7S RS13630
gene id: 391936:S7S_RS13630
uniprot id: A0A0B4XPK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

391936:S7S RS12535
gene id: 391936:S7S_RS12535
uniprot id: A0A0B4XR42
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

391936:S7S RS02980
gene id: 391936:S7S_RS02980
uniprot id: A0A0B4XKH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

391936:S7S RS00575
gene id: 391936:S7S_RS00575
uniprot id: A0A0B4XEU7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

391936:S7S RS15200
gene id: 391936:S7S_RS15200
uniprot id: A0A0B4XT11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS09575
gene id: 391936:S7S_RS09575
uniprot id: A0A0B4XPY2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

391936:S7S RS00680
gene id: 391936:S7S_RS00680
uniprot id: A0A0B4XIN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

391936:S7S RS00410
gene id: 391936:S7S_RS00410
uniprot id: A0A0B4XHH4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS15750
gene id: 391936:S7S_RS15750
uniprot id: A0A0B4XQT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

391936:S7S RS15235
gene id: 391936:S7S_RS15235
uniprot id: A0A0B4XSR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

391936:S7S RS06680
gene id: 391936:S7S_RS06680
uniprot id: A0A0B4XHV1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

391936:S7S RS03240
gene id: 391936:S7S_RS03240
uniprot id: A0A0B4XK58
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

391936:S7S RS01010
gene id: 391936:S7S_RS01010
uniprot id: A0A0B4XHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

391936:S7S RS15745
gene id: 391936:S7S_RS15745
uniprot id: A0A0B4XS02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

391936:S7S RS17685
gene id: 391936:S7S_RS17685
uniprot id: A0A0B4XNI9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

391936:S7S RS09450
gene id: 391936:S7S_RS09450
uniprot id: A0A0B4XPV3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

391936:S7S RS16870
gene id: 391936:S7S_RS16870
uniprot id: A0A0B4XTD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS12495
gene id: 391936:S7S_RS12495
uniprot id: A0A0B4XQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

391936:S7S RS07075
gene id: 391936:S7S_RS07075
uniprot id: A0A0B4XI35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

391936:S7S RS00890
gene id: 391936:S7S_RS00890
uniprot id: A0A0B4XHR3
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

391936:S7S RS02020
gene id: 391936:S7S_RS02020
uniprot id: A0A0B4XK85
names: Similarity
messages: Belongs to the thioredoxin family.

391936:S7S RS14305
gene id: 391936:S7S_RS14305
uniprot id: A0A0B4XSI5
names: Similarity
messages: Belongs to the CopC family.

391936:S7S RS13835
gene id: 391936:S7S_RS13835
uniprot id: A0A0B4XSB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

391936:S7S RS00535
gene id: 391936:S7S_RS00535
uniprot id: A0A0B4XHK0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

391936:S7S RS06945
gene id: 391936:S7S_RS06945
uniprot id: A0A0B4XNB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

391936:S7S RS08285
gene id: 391936:S7S_RS08285
uniprot id: A0A0B4XP59
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

391936:S7S RS10530
gene id: 391936:S7S_RS10530
uniprot id: A0A0B4XJR7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

391936:S7S RS18915
gene id: 391936:S7S_RS18915
uniprot id: A0A0B4XQE6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

391936:S7S RS17435
gene id: 391936:S7S_RS17435
uniprot id: A0A0B4XNC2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

391936:S7S RS16820
gene id: 391936:S7S_RS16820
uniprot id: A0A0B4XTB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

391936:S7S RS02485
gene id: 391936:S7S_RS02485
uniprot id: A0A0B4XIP7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

391936:S7S RS05235
gene id: 391936:S7S_RS05235
uniprot id: A0A0B4XK70
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS06060
gene id: 391936:S7S_RS06060
uniprot id: A0A0B4XM49
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS18770
gene id: 391936:S7S_RS18770
uniprot id: A0A0B4XMD0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

391936:S7S RS04550
gene id: 391936:S7S_RS04550
uniprot id: A0A0B4XGT5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

391936:S7S RS13780
gene id: 391936:S7S_RS13780
uniprot id: A0A0B4XPM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

391936:S7S RS08445
gene id: 391936:S7S_RS08445
uniprot id: A0A0B4XLU0
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

391936:S7S RS12835
gene id: 391936:S7S_RS12835
uniprot id: A0A0B4XRX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

391936:S7S RS04885
gene id: 391936:S7S_RS04885
uniprot id: A0A0B4XJY7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

391936:S7S RS04890
gene id: 391936:S7S_RS04890
uniprot id: A0A0B4XM21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

391936:S7S RS08040
gene id: 391936:S7S_RS08040
uniprot id: A0A0B4XNH9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

391936:S7S RS08980
gene id: 391936:S7S_RS08980
uniprot id: A0A0B4XNY6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

391936:S7S RS13470
gene id: 391936:S7S_RS13470
uniprot id: A0A0B4XLE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

391936:S7S RS16120
gene id: 391936:S7S_RS16120
uniprot id: A0A0B4XMM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

391936:S7S RS04880
gene id: 391936:S7S_RS04880
uniprot id: A0A0B4XL27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

391936:S7S RS04825
gene id: 391936:S7S_RS04825
uniprot id: A0A0B4XGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

391936:S7S RS14850
gene id: 391936:S7S_RS14850
uniprot id: A0A0B4XSS4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

391936:S7S RS13260
gene id: 391936:S7S_RS13260
uniprot id: A0A0B4XRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

391936:S7S RS14715
gene id: 391936:S7S_RS14715
uniprot id: A0A0B4XRC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

391936:S7S RS17365
gene id: 391936:S7S_RS17365
uniprot id: A0A0B4XRP5
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

391936:S7S RS02360
gene id: 391936:S7S_RS02360
uniprot id: A0A0B4XJN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

391936:S7S RS03300
gene id: 391936:S7S_RS03300
uniprot id: A0A0B4XK65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

391936:S7S RS01635
gene id: 391936:S7S_RS01635
uniprot id: A0A0B4XI51
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

391936:S7S RS00910
gene id: 391936:S7S_RS00910
uniprot id: A0A0B4XIS6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

391936:S7S RS04960
gene id: 391936:S7S_RS04960
uniprot id: A0A0B4XK02
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

391936:S7S RS18935
gene id: 391936:S7S_RS18935
uniprot id: A0A0B4XST4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

391936:S7S RS06765
gene id: 391936:S7S_RS06765
uniprot id: A0A0B4XKX7
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS00325
gene id: 391936:S7S_RS00325
uniprot id: A0A0B4XEQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

391936:S7S RS14765
gene id: 391936:S7S_RS14765
uniprot id: A0A0B4XRD8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

391936:S7S RS04210
gene id: 391936:S7S_RS04210
uniprot id: A0A0B4XJM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

391936:S7S RS03845
gene id: 391936:S7S_RS03845
uniprot id: A0A0B4XLB9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

391936:S7S RS06720
gene id: 391936:S7S_RS06720
uniprot id: A0A0B4XN72
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS05715
gene id: 391936:S7S_RS05715
uniprot id: A0A0B4XHE1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS04270
gene id: 391936:S7S_RS04270
uniprot id: A0A0B4XL20
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS01120
gene id: 391936:S7S_RS01120
uniprot id: A0A0B4XJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

391936:S7S RS18650
gene id: 391936:S7S_RS18650
uniprot id: A0A0B4XSE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

391936:S7S RS05110
gene id: 391936:S7S_RS05110
uniprot id: A0A0B4XK55
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS13765
gene id: 391936:S7S_RS13765
uniprot id: A0A0B4XRQ8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS07450
gene id: 391936:S7S_RS07450
uniprot id: A0A0B4XN31
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

391936:S7S RS12015
gene id: 391936:S7S_RS12015
uniprot id: A0A0B4XQS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

391936:S7S RS02090
gene id: 391936:S7S_RS02090
uniprot id: A0A0B4XID2
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

391936:S7S RS18245
gene id: 391936:S7S_RS18245
uniprot id: A0A0B4XS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

391936:S7S RS08245
gene id: 391936:S7S_RS08245
uniprot id: A0A0B4XIJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS12590
gene id: 391936:S7S_RS12590
uniprot id: A0A0B4XKX1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS06670
gene id: 391936:S7S_RS06670
uniprot id: A0A0B4XN61
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

391936:S7S RS14740
gene id: 391936:S7S_RS14740
uniprot id: A0A0B4XRD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

391936:S7S RS16390
gene id: 391936:S7S_RS16390
uniprot id: A0A0B4XTP3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

391936:S7S RS12770
gene id: 391936:S7S_RS12770
uniprot id: A0A0B4XL42
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

391936:S7S RS09020
gene id: 391936:S7S_RS09020
uniprot id: A0A0B4XM46
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS02950
gene id: 391936:S7S_RS02950
uniprot id: A0A0B4XIY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

391936:S7S RS07720
gene id: 391936:S7S_RS07720
uniprot id: A0A0B4XLJ1
names: Similarity
messages: Belongs to the YciI family.

391936:S7S RS03900
gene id: 391936:S7S_RS03900
uniprot id: A0A0B4XKT9
names: Similarity
messages: Belongs to the AHA1 family.

391936:S7S RS11740
gene id: 391936:S7S_RS11740
uniprot id: A0A0B4XQK8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

391936:S7S RS07265
gene id: 391936:S7S_RS07265
uniprot id: A0A0B4XL65
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

391936:S7S RS10495
gene id: 391936:S7S_RS10495
uniprot id: A0A0B4XQ01
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS11845
gene id: 391936:S7S_RS11845
uniprot id: A0A0B4XKF7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

391936:S7S RS17555
gene id: 391936:S7S_RS17555
uniprot id: A0A0B4XTU0
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

391936:S7S RS10470
gene id: 391936:S7S_RS10470
uniprot id: A0A0B4XJQ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

391936:S7S RS05680
gene id: 391936:S7S_RS05680
uniprot id: A0A0B4XMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

391936:S7S RS00555
gene id: 391936:S7S_RS00555
uniprot id: A0A0B4XIL4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

391936:S7S RS00745
gene id: 391936:S7S_RS00745
uniprot id: A0A0B4XJ32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

391936:S7S RS14005
gene id: 391936:S7S_RS14005
uniprot id: A0A0B4XPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS03520
gene id: 391936:S7S_RS03520
uniprot id: A0A0B4XKP2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

391936:S7S RS00050
gene id: 391936:S7S_RS00050
uniprot id: A0A0B4XEI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

391936:S7S RS06965
gene id: 391936:S7S_RS06965
uniprot id: A0A0B4XNC1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

391936:S7S RS04150
gene id: 391936:S7S_RS04150
uniprot id: A0A0B4XGL3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

391936:S7S RS15580
gene id: 391936:S7S_RS15580
uniprot id: A0A0B4XT85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

391936:S7S RS13135
gene id: 391936:S7S_RS13135
uniprot id: A0A0B4XRI1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS04090
gene id: 391936:S7S_RS04090
uniprot id: A0A0B4XLH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS12305
gene id: 391936:S7S_RS12305
uniprot id: A0A0B4XRH3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

391936:S7S RS17870
gene id: 391936:S7S_RS17870
uniprot id: A0A0B4XS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS09000
gene id: 391936:S7S_RS09000
uniprot id: A0A0B4XPL6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

391936:S7S RS02815
gene id: 391936:S7S_RS02815
uniprot id: A0A0B4XG23
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

391936:S7S RS14815
gene id: 391936:S7S_RS14815
uniprot id: A0A0B4XRF0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

391936:S7S RS04725
gene id: 391936:S7S_RS04725
uniprot id: A0A0B4XGW6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

391936:S7S RS08505
gene id: 391936:S7S_RS08505
uniprot id: A0A0B4XNQ8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

391936:S7S RS04070
gene id: 391936:S7S_RS04070
uniprot id: A0A0B4XKX4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

391936:S7S RS15930
gene id: 391936:S7S_RS15930
uniprot id: A0A0B4XQX0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

391936:S7S RS03720
gene id: 391936:S7S_RS03720
uniprot id: A0A0B4XLA1
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS06095
gene id: 391936:S7S_RS06095
uniprot id: A0A0B4XLR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

391936:S7S RS09160
gene id: 391936:S7S_RS09160
uniprot id: A0A0B4XN93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

391936:S7S RS09565
gene id: 391936:S7S_RS09565
uniprot id: A0A0B4XNH2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

391936:S7S RS02935
gene id: 391936:S7S_RS02935
uniprot id: A0A0B4XKG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

391936:S7S RS17845
gene id: 391936:S7S_RS17845
uniprot id: A0A0B4XS16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

391936:S7S RS17530
gene id: 391936:S7S_RS17530
uniprot id: A0A0B4XTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

391936:S7S RS03615
gene id: 391936:S7S_RS03615
uniprot id: A0A0B4XJC2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS09860
gene id: 391936:S7S_RS09860
uniprot id: A0A0B4XJB2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

391936:S7S RS02855
gene id: 391936:S7S_RS02855
uniprot id: A0A0B4XKW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

391936:S7S RS02970
gene id: 391936:S7S_RS02970
uniprot id: A0A0B4XK23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

391936:S7S RS00965
gene id: 391936:S7S_RS00965
uniprot id: A0A0B4XJL7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

391936:S7S RS16970
gene id: 391936:S7S_RS16970
uniprot id: A0A0B4XRG6
names: Similarity
messages: Belongs to the UPF0319 family.

391936:S7S RS13215
gene id: 391936:S7S_RS13215
uniprot id: A0A0B4XQI0
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

391936:S7S RS14240
gene id: 391936:S7S_RS14240
uniprot id: A0A0B4XS06
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS00865
gene id: 391936:S7S_RS00865
uniprot id: A0A0B4XHR1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

391936:S7S RS16300
gene id: 391936:S7S_RS16300
uniprot id: A0A0B4XMP8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

391936:S7S RS06530
gene id: 391936:S7S_RS06530
uniprot id: A0A0B4XKT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

391936:S7S RS01340
gene id: 391936:S7S_RS01340
uniprot id: A0A0B4XJF2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

391936:S7S RS01020
gene id: 391936:S7S_RS01020
uniprot id: A0A0B4XJ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

391936:S7S RS16685
gene id: 391936:S7S_RS16685
uniprot id: A0A0B4XRA6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

391936:S7S RS02845
gene id: 391936:S7S_RS02845
uniprot id: A0A0B4XK04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

391936:S7S RS17875
gene id: 391936:S7S_RS17875
uniprot id: A0A0B4XUP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

391936:S7S RS17415
gene id: 391936:S7S_RS17415
uniprot id: A0A0B4XRQ4
names: Similarity
messages: Belongs to the Dps family.

391936:S7S RS10315
gene id: 391936:S7S_RS10315
uniprot id: A0A0B4XN27
names: Similarity
messages: Belongs to the peptidase M1 family.

391936:S7S RS08195
gene id: 391936:S7S_RS08195
uniprot id: A0A0B4XII6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

391936:S7S RS17895
gene id: 391936:S7S_RS17895
uniprot id: A0A0B4XS26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

391936:S7S RS07100
gene id: 391936:S7S_RS07100
uniprot id: A0A0B4XI40
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS05270
gene id: 391936:S7S_RS05270
uniprot id: A0A0B4XLS1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

391936:S7S RS14870
gene id: 391936:S7S_RS14870
uniprot id: A0A0B4XQ81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

391936:S7S RS12580
gene id: 391936:S7S_RS12580
uniprot id: A0A0B4XRN6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS16690
gene id: 391936:S7S_RS16690
uniprot id: A0A0B4XTW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

391936:S7S RS12175
gene id: 391936:S7S_RS12175
uniprot id: A0A0B4XNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

391936:S7S RS17925
gene id: 391936:S7S_RS17925
uniprot id: A0A0B4XUQ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

391936:S7S RS17490
gene id: 391936:S7S_RS17490
uniprot id: A0A0B4XT65
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS04900
gene id: 391936:S7S_RS04900
uniprot id: A0A0B4XGZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

391936:S7S RS13540
gene id: 391936:S7S_RS13540
uniprot id: A0A0B4XRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

391936:S7S RS09830
gene id: 391936:S7S_RS09830
uniprot id: A0A0B4XPJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

391936:S7S RS02615
gene id: 391936:S7S_RS02615
uniprot id: A0A0B4XKA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

391936:S7S RS00715
gene id: 391936:S7S_RS00715
uniprot id: A0A0B4XJH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

391936:S7S RS04615
gene id: 391936:S7S_RS04615
uniprot id: A0A0B4XLV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

391936:S7S RS15270
gene id: 391936:S7S_RS15270
uniprot id: A0A0B4XRS9
names: Similarity
messages: Belongs to the UPF0434 family.

391936:S7S RS15265
gene id: 391936:S7S_RS15265
uniprot id: A0A0B4XMC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS17795
gene id: 391936:S7S_RS17795
uniprot id: A0A0B4XS05
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

391936:S7S RS15435
gene id: 391936:S7S_RS15435
uniprot id: A0A0B4XSU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS08865
gene id: 391936:S7S_RS08865
uniprot id: A0A0B4XN51
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS16575
gene id: 391936:S7S_RS16575
uniprot id: A0A0B4XR88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

391936:S7S RS05035
gene id: 391936:S7S_RS05035
uniprot id: A0A0B4XK25
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS00565
gene id: 391936:S7S_RS00565
uniprot id: A0A0B4XJE6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

391936:S7S RS13905
gene id: 391936:S7S_RS13905
uniprot id: A0A0B4XPQ1
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

391936:S7S RS10690
gene id: 391936:S7S_RS10690
uniprot id: A0A0B4XJU5
names: Similarity
messages: Belongs to the HepT RNase toxin family.

391936:S7S RS02860
gene id: 391936:S7S_RS02860
uniprot id: A0A0B4XIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

391936:S7S RS07860
gene id: 391936:S7S_RS07860
uniprot id: A0A0B4XIF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

391936:S7S RS13355
gene id: 391936:S7S_RS13355
uniprot id: A0A0B4XS38
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

391936:S7S RS06375
gene id: 391936:S7S_RS06375
uniprot id: A0A0B4XLY0
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

391936:S7S RS10040
gene id: 391936:S7S_RS10040
uniprot id: A0A0B4XMS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

391936:S7S RS01375
gene id: 391936:S7S_RS01375
uniprot id: A0A0B4XJ21
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS00040
gene id: 391936:S7S_RS00040
uniprot id: A0A0B4XJ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

391936:S7S RS12190
gene id: 391936:S7S_RS12190
uniprot id: A0A0B4XKM1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

391936:S7S RS07990
gene id: 391936:S7S_RS07990
uniprot id: A0A0B4XNH1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

391936:S7S RS08510
gene id: 391936:S7S_RS08510
uniprot id: A0A0B4XIL6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

391936:S7S RS12440
gene id: 391936:S7S_RS12440
uniprot id: A0A0B4XKT2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

391936:S7S RS17600
gene id: 391936:S7S_RS17600
uniprot id: A0A0B4XUH9
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS05930
gene id: 391936:S7S_RS05930
uniprot id: A0A0B4XM24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS03940
gene id: 391936:S7S_RS03940
uniprot id: A0A0B4XJI5
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

391936:S7S RS02925
gene id: 391936:S7S_RS02925
uniprot id: A0A0B4XIY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

391936:S7S RS05025
gene id: 391936:S7S_RS05025
uniprot id: A0A0B4XH20
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

391936:S7S RS08225
gene id: 391936:S7S_RS08225
uniprot id: A0A0B4XMZ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS15835
gene id: 391936:S7S_RS15835
uniprot id: A0A0B4XTC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

391936:S7S RS11470
gene id: 391936:S7S_RS11470
uniprot id: A0A0B4XPU9
names: Similarity
messages: Belongs to the transposase 8 family.

391936:S7S RS03230
gene id: 391936:S7S_RS03230
uniprot id: A0A0B4XKK9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

391936:S7S RS13635
gene id: 391936:S7S_RS13635
uniprot id: A0A0B4XS80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

391936:S7S RS06785
gene id: 391936:S7S_RS06785
uniprot id: A0A0B4XM75
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS02015
gene id: 391936:S7S_RS02015
uniprot id: A0A0B4XIB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

391936:S7S RS13400
gene id: 391936:S7S_RS13400
uniprot id: A0A0B4XPI6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS01735
gene id: 391936:S7S_RS01735
uniprot id: A0A0B4XI71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS16945
gene id: 391936:S7S_RS16945
uniprot id: A0A0B4XRG3
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

391936:S7S RS13805
gene id: 391936:S7S_RS13805
uniprot id: A0A0B4XPN4
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

391936:S7S RS06405
gene id: 391936:S7S_RS06405
uniprot id: A0A0B4XKR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

391936:S7S RS15825
gene id: 391936:S7S_RS15825
uniprot id: A0A0B4XS14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

391936:S7S RS15020
gene id: 391936:S7S_RS15020
uniprot id: A0A0B4XQB6
names: Similarity
messages: Belongs to the UPF0229 family.

391936:S7S RS13645
gene id: 391936:S7S_RS13645
uniprot id: A0A0B4XLG8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

391936:S7S RS03210
gene id: 391936:S7S_RS03210
uniprot id: A0A0B4XG66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS14655
gene id: 391936:S7S_RS14655
uniprot id: A0A0B4XSC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

391936:S7S RS13060
gene id: 391936:S7S_RS13060
uniprot id: A0A0B4XL87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

391936:S7S RS03735
gene id: 391936:S7S_RS03735
uniprot id: A0A0B4XKD1
names: Similarity
messages: Belongs to the HesB/IscA family.

391936:S7S RS14680
gene id: 391936:S7S_RS14680
uniprot id: A0A0B4XSC9
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

391936:S7S RS12200
gene id: 391936:S7S_RS12200
uniprot id: A0A0B4XNZ0
names: Similarity
messages: Belongs to the ArsC family.

391936:S7S RS01275
gene id: 391936:S7S_RS01275
uniprot id: A0A0B4XJ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

391936:S7S RS13810
gene id: 391936:S7S_RS13810
uniprot id: A0A0B4XSA8
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS04300
gene id: 391936:S7S_RS04300
uniprot id: A0A0B4XGP1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

391936:S7S RS04490
gene id: 391936:S7S_RS04490
uniprot id: A0A0B4XLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

391936:S7S RS00005
gene id: 391936:S7S_RS00005
uniprot id: A0A0B4XI76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

391936:S7S RS04250
gene id: 391936:S7S_RS04250
uniprot id: A0A0B4XGN1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

391936:S7S RS10430
gene id: 391936:S7S_RS10430
uniprot id: A0A0B4XQI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

391936:S7S RS15645
gene id: 391936:S7S_RS15645
uniprot id: A0A0B4XRY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

391936:S7S RS07900
gene id: 391936:S7S_RS07900
uniprot id: A0A0B4XNZ1
names: Similarity
messages: Belongs to the MlaA family.

391936:S7S RS07270
gene id: 391936:S7S_RS07270
uniprot id: A0A0B4XNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS02850
gene id: 391936:S7S_RS02850
uniprot id: A0A0B4XIX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

391936:S7S RS01800
gene id: 391936:S7S_RS01800
uniprot id: A0A0B4XFF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

391936:S7S RS10465
gene id: 391936:S7S_RS10465
uniprot id: A0A0B4XPZ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

391936:S7S RS10805
gene id: 391936:S7S_RS10805
uniprot id: A0A0B4XQP3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

391936:S7S RS13840
gene id: 391936:S7S_RS13840
uniprot id: A0A0B4XRS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

391936:S7S RS14235
gene id: 391936:S7S_RS14235
uniprot id: A0A0B4XSH3
names: Similarity
messages: Belongs to the TrpC family.

391936:S7S RS03660
gene id: 391936:S7S_RS03660
uniprot id: A0A0B4XKB7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

391936:S7S RS13940
gene id: 391936:S7S_RS13940
uniprot id: A0A0B4XRT8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

391936:S7S RS08985
gene id: 391936:S7S_RS08985
uniprot id: A0A0B4XIS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

391936:S7S RS02030
gene id: 391936:S7S_RS02030
uniprot id: A0A0B4XFK2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

391936:S7S RS02420
gene id: 391936:S7S_RS02420
uniprot id: A0A0B4XK29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

391936:S7S RS02805
gene id: 391936:S7S_RS02805
uniprot id: A0A0B4XKV4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS10540
gene id: 391936:S7S_RS10540
uniprot id: A0A0B4XN58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS07020
gene id: 391936:S7S_RS07020
uniprot id: A0A0B4XMR7
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

391936:S7S RS00030
gene id: 391936:S7S_RS00030
uniprot id: A0A0B4XI83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

391936:S7S RS08590
gene id: 391936:S7S_RS08590
uniprot id: A0A0B4XN23
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

391936:S7S RS07755
gene id: 391936:S7S_RS07755
uniprot id: A0A0B4XND0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

391936:S7S RS04990
gene id: 391936:S7S_RS04990
uniprot id: A0A0B4XM48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

391936:S7S RS11955
gene id: 391936:S7S_RS11955
uniprot id: A0A0B4XNU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

391936:S7S RS17610
gene id: 391936:S7S_RS17610
uniprot id: A0A0B4XNG8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS17150
gene id: 391936:S7S_RS17150
uniprot id: A0A0B4XTJ0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

391936:S7S RS16260
gene id: 391936:S7S_RS16260
uniprot id: A0A0B4XTL8
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

391936:S7S RS11830
gene id: 391936:S7S_RS11830
uniprot id: A0A0B4XNR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

391936:S7S RS02450
gene id: 391936:S7S_RS02450
uniprot id: A0A0B4XFU6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

391936:S7S RS18485
gene id: 391936:S7S_RS18485
uniprot id: A0A0B4XP05
names: Subcellular Location Annotation
messages: Cytoplasm

391936:S7S RS08270
gene id: 391936:S7S_RS08270
uniprot id: A0A0B4XIJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

391936:S7S RS00740
gene id: 391936:S7S_RS00740
uniprot id: A0A0B4XJH9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

391936:S7S RS06155
gene id: 391936:S7S_RS06155
uniprot id: A0A0B4XMT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS12180
gene id: 391936:S7S_RS12180
uniprot id: A0A0B4XRF3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

391936:S7S RS17475
gene id: 391936:S7S_RS17475
uniprot id: A0A0B4XUE7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS06300
gene id: 391936:S7S_RS06300
uniprot id: A0A0B4XKP7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

391936:S7S RS08465
gene id: 391936:S7S_RS08465
uniprot id: A0A0B4XN12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

391936:S7S RS10155
gene id: 391936:S7S_RS10155
uniprot id: A0A0B4XJH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

391936:S7S RS16660
gene id: 391936:S7S_RS16660
uniprot id: A0A0B4XRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

391936:S7S RS18430
gene id: 391936:S7S_RS18430
uniprot id: A0A0B4XUC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

391936:S7S RS04485
gene id: 391936:S7S_RS04485
uniprot id: A0A0B4XJR6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

391936:S7S RS00945
gene id: 391936:S7S_RS00945
uniprot id: A0A0B4XJ71
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

391936:S7S RS03905
gene id: 391936:S7S_RS03905
uniprot id: A0A0B4XGG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS16280
gene id: 391936:S7S_RS16280
uniprot id: A0A0B4XR31
names: Similarity
messages: Belongs to the band 7/mec-2 family.

391936:S7S RS04505
gene id: 391936:S7S_RS04505
uniprot id: A0A0B4XKW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

391936:S7S RS14820
gene id: 391936:S7S_RS14820
uniprot id: A0A0B4XQ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

391936:S7S RS06020
gene id: 391936:S7S_RS06020
uniprot id: A0A0B4XLP8
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS12235
gene id: 391936:S7S_RS12235
uniprot id: A0A0B4XQX9
names: Similarity
messages: Belongs to the CvfB family.

391936:S7S RS08455
gene id: 391936:S7S_RS08455
uniprot id: A0A0B4XNP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

391936:S7S RS13700
gene id: 391936:S7S_RS13700
uniprot id: A0A0B4XQR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

391936:S7S RS10205
gene id: 391936:S7S_RS10205
uniprot id: A0A0B4XJK9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS17220
gene id: 391936:S7S_RS17220
uniprot id: A0A0B4XU92
names: Similarity
messages: Belongs to the peptidase S45 family.

391936:S7S RS18040
gene id: 391936:S7S_RS18040
uniprot id: A0A0B4XTJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

391936:S7S RS06305
gene id: 391936:S7S_RS06305
uniprot id: A0A0B4XMX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

391936:S7S RS02985
gene id: 391936:S7S_RS02985
uniprot id: A0A0B4XG42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

391936:S7S RS02870
gene id: 391936:S7S_RS02870
uniprot id: A0A0B4XK07
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

391936:S7S RS08460
gene id: 391936:S7S_RS08460
uniprot id: A0A0B4XIL3
names: Similarity
messages: Belongs to the fabD family.

391936:S7S RS16605
gene id: 391936:S7S_RS16605
uniprot id: A0A0B4XSJ0
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

391936:S7S RS03765
gene id: 391936:S7S_RS03765
uniprot id: A0A0B4XJF0
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

391936:S7S RS01135
gene id: 391936:S7S_RS01135
uniprot id: A0A0B4XHV4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

391936:S7S RS12330
gene id: 391936:S7S_RS12330
uniprot id: A0A0B4XRH7
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

391936:S7S RS14205
gene id: 391936:S7S_RS14205
uniprot id: A0A0B4XPU5
names: Similarity
messages: Belongs to the YciI family.

391936:S7S RS01130
gene id: 391936:S7S_RS01130
uniprot id: A0A0B4XIX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS06075
gene id: 391936:S7S_RS06075
uniprot id: A0A0B4XKL0
names: Similarity
messages: Belongs to the ArsC family.

391936:S7S RS06995
gene id: 391936:S7S_RS06995
uniprot id: A0A0B4XMR2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

391936:S7S RS06410
gene id: 391936:S7S_RS06410
uniprot id: A0A0B4XMZ2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

391936:S7S RS00930
gene id: 391936:S7S_RS00930
uniprot id: A0A0B4XF12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

391936:S7S RS13360
gene id: 391936:S7S_RS13360
uniprot id: A0A0B4XRK6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

391936:S7S RS14990
gene id: 391936:S7S_RS14990
uniprot id: A0A0B4XRJ2
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

391936:S7S RS06610
gene id: 391936:S7S_RS06610
uniprot id: A0A0B4XM32
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS05020
gene id: 391936:S7S_RS05020
uniprot id: A0A0B4XLJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS17835
gene id: 391936:S7S_RS17835
uniprot id: A0A0B4XNP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

391936:S7S RS12435
gene id: 391936:S7S_RS12435
uniprot id: A0A0B4XR21
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

391936:S7S RS07480
gene id: 391936:S7S_RS07480
uniprot id: A0A0B4XI97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

391936:S7S RS11110
gene id: 391936:S7S_RS11110
uniprot id: A0A0B4XQ94
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

391936:S7S RS03450
gene id: 391936:S7S_RS03450
uniprot id: A0A0B4XG95
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS07630
gene id: 391936:S7S_RS07630
uniprot id: A0A0B4XNA6
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS10730
gene id: 391936:S7S_RS10730
uniprot id: A0A0B4XQM9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

391936:S7S RS11970
gene id: 391936:S7S_RS11970
uniprot id: A0A0B4XKI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

391936:S7S RS13755
gene id: 391936:S7S_RS13755
uniprot id: A0A0B4XPM4
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

391936:S7S RS12675
gene id: 391936:S7S_RS12675
uniprot id: A0A0B4XQA0
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS02405
gene id: 391936:S7S_RS02405
uniprot id: A0A0B4XJP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

391936:S7S RS05550
gene id: 391936:S7S_RS05550
uniprot id: A0A0B4XLW1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

391936:S7S RS03825
gene id: 391936:S7S_RS03825
uniprot id: A0A0B4XKS6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

391936:S7S RS10425
gene id: 391936:S7S_RS10425
uniprot id: A0A0B4XN46
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

391936:S7S RS03195
gene id: 391936:S7S_RS03195
uniprot id: A0A0B4XJ35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

391936:S7S RS18050
gene id: 391936:S7S_RS18050
uniprot id: A0A0B4XUT0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

391936:S7S RS15255
gene id: 391936:S7S_RS15255
uniprot id: A0A0B4XT36
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

391936:S7S RS07090
gene id: 391936:S7S_RS07090
uniprot id: A0A0B4XNF0
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

391936:S7S RS01390
gene id: 391936:S7S_RS01390
uniprot id: A0A0B4XJG2
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS16860
gene id: 391936:S7S_RS16860
uniprot id: A0A0B4XRE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

391936:S7S RS13160
gene id: 391936:S7S_RS13160
uniprot id: A0A0B4XRI3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

391936:S7S RS15070
gene id: 391936:S7S_RS15070
uniprot id: A0A0B4XSY0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

391936:S7S RS01030
gene id: 391936:S7S_RS01030
uniprot id: A0A0B4XIV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

391936:S7S RS15385
gene id: 391936:S7S_RS15385
uniprot id: A0A0B4XST6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS03860
gene id: 391936:S7S_RS03860
uniprot id: A0A0B4XKF6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

391936:S7S RS10505
gene id: 391936:S7S_RS10505
uniprot id: A0A0B4XJR3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

391936:S7S RS01440
gene id: 391936:S7S_RS01440
uniprot id: A0A0B4XJV8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

391936:S7S RS05405
gene id: 391936:S7S_RS05405
uniprot id: A0A0B4XLF0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

391936:S7S RS01680
gene id: 391936:S7S_RS01680
uniprot id: A0A0B4XJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

391936:S7S RS10515
gene id: 391936:S7S_RS10515
uniprot id: A0A0B4XN55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

391936:S7S RS02915
gene id: 391936:S7S_RS02915
uniprot id: A0A0B4XG32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

391936:S7S RS09605
gene id: 391936:S7S_RS09605
uniprot id: A0A0B4XPC2
names: Similarity
messages: Belongs to the PrpF family.

391936:S7S RS11415
gene id: 391936:S7S_RS11415
uniprot id: A0A0B4XQD5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS01035
gene id: 391936:S7S_RS01035
uniprot id: A0A0B4XHT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

391936:S7S RS08025
gene id: 391936:S7S_RS08025
uniprot id: A0A0B4XMX0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

391936:S7S RS00425
gene id: 391936:S7S_RS00425
uniprot id: A0A0B4XES1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

391936:S7S RS05885
gene id: 391936:S7S_RS05885
uniprot id: A0A0B4XHG9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

391936:S7S RS12480
gene id: 391936:S7S_RS12480
uniprot id: A0A0B4XRL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

391936:S7S RS16975
gene id: 391936:S7S_RS16975
uniprot id: A0A0B4XU32
names: Similarity
messages: Belongs to the UPF0047 family.

391936:S7S RS04065
gene id: 391936:S7S_RS04065
uniprot id: A0A0B4XLH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

391936:S7S RS01025
gene id: 391936:S7S_RS01025
uniprot id: A0A0B4XF29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

391936:S7S RS03205
gene id: 391936:S7S_RS03205
uniprot id: A0A0B4XKK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

391936:S7S RS15010
gene id: 391936:S7S_RS15010
uniprot id: A0A0B4XM80
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

391936:S7S RS05870
gene id: 391936:S7S_RS05870
uniprot id: A0A0B4XKH3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

391936:S7S RS08730
gene id: 391936:S7S_RS08730
uniprot id: A0A0B4XNU4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

391936:S7S RS03035
gene id: 391936:S7S_RS03035
uniprot id: A0A0B4XG46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

391936:S7S RS04985
gene id: 391936:S7S_RS04985
uniprot id: A0A0B4XK10
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

391936:S7S RS05480
gene id: 391936:S7S_RS05480
uniprot id: A0A0B4XLG0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

391936:S7S RS05850
gene id: 391936:S7S_RS05850
uniprot id: A0A0B4XMN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

391936:S7S RS10085
gene id: 391936:S7S_RS10085
uniprot id: A0A0B4XNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

391936:S7S RS14835
gene id: 391936:S7S_RS14835
uniprot id: A0A0B4XM52
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

391936:S7S RS01870
gene id: 391936:S7S_RS01870
uniprot id: A0A0B4XK46
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS08470
gene id: 391936:S7S_RS08470
uniprot id: A0A0B4XLU3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

391936:S7S RS12795
gene id: 391936:S7S_RS12795
uniprot id: A0A0B4XL47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

391936:S7S RS19630
gene id: 391936:S7S_RS19630
uniprot id: A0A0B4XNX7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS10725
gene id: 391936:S7S_RS10725
uniprot id: A0A0B4XN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS02960
gene id: 391936:S7S_RS02960
uniprot id: A0A0B4XKG9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

391936:S7S RS08585
gene id: 391936:S7S_RS08585
uniprot id: A0A0B4XIM6
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

391936:S7S RS12025
gene id: 391936:S7S_RS12025
uniprot id: A0A0B4XPV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

391936:S7S RS16845
gene id: 391936:S7S_RS16845
uniprot id: A0A0B4XTC5
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS14780
gene id: 391936:S7S_RS14780
uniprot id: A0A0B4XSF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

391936:S7S RS18335
gene id: 391936:S7S_RS18335
uniprot id: A0A0B4XNX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

391936:S7S RS06940
gene id: 391936:S7S_RS06940
uniprot id: A0A0B4XL02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

391936:S7S RS11930
gene id: 391936:S7S_RS11930
uniprot id: A0A0B4XRA9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

391936:S7S RS00270
gene id: 391936:S7S_RS00270
uniprot id: A0A0B4XIV1
names: Similarity
messages: Belongs to the RutC family.

391936:S7S RS12320
gene id: 391936:S7S_RS12320
uniprot id: A0A0B4XQ26
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

391936:S7S RS15380
gene id: 391936:S7S_RS15380
uniprot id: A0A0B4XT51
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

391936:S7S RS12430
gene id: 391936:S7S_RS12430
uniprot id: A0A0B4XRK0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

391936:S7S RS18250
gene id: 391936:S7S_RS18250
uniprot id: A0A0B4XUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

391936:S7S RS11720
gene id: 391936:S7S_RS11720
uniprot id: A0A0B4XPQ7
names: Similarity
messages: Belongs to the MipA/OmpV family.

391936:S7S RS03780
gene id: 391936:S7S_RS03780
uniprot id: A0A0B4XGE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

391936:S7S RS13310
gene id: 391936:S7S_RS13310
uniprot id: A0A0B4XRJ9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

391936:S7S RS01415
gene id: 391936:S7S_RS01415
uniprot id: A0A0B4XJV4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

391936:S7S RS08725
gene id: 391936:S7S_RS08725
uniprot id: A0A0B4XPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

391936:S7S RS07915
gene id: 391936:S7S_RS07915
uniprot id: A0A0B4XMW1
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

391936:S7S RS10150
gene id: 391936:S7S_RS10150
uniprot id: A0A0B4XPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

391936:S7S RS00995
gene id: 391936:S7S_RS00995
uniprot id: A0A0B4XJ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

391936:S7S RS00010
gene id: 391936:S7S_RS00010
uniprot id: A0A0B4XH63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

391936:S7S RS02835
gene id: 391936:S7S_RS02835
uniprot id: A0A0B4XKE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

391936:S7S RS14855
gene id: 391936:S7S_RS14855
uniprot id: A0A0B4XSH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

391936:S7S RS17140
gene id: 391936:S7S_RS17140
uniprot id: A0A0B4XRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

391936:S7S RS13625
gene id: 391936:S7S_RS13625
uniprot id: A0A0B4XQP9
names: Similarity
messages: Belongs to the SCO1/2 family.

391936:S7S RS15175
gene id: 391936:S7S_RS15175
uniprot id: A0A0B4XT06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS07715
gene id: 391936:S7S_RS07715
uniprot id: A0A0B4XMU2
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS17050
gene id: 391936:S7S_RS17050
uniprot id: A0A0B4XU48
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS17640
gene id: 391936:S7S_RS17640
uniprot id: A0A0B4XT99
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

391936:S7S RS03695
gene id: 391936:S7S_RS03695
uniprot id: A0A0B4XL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

391936:S7S RS15830
gene id: 391936:S7S_RS15830
uniprot id: A0A0B4XQV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

391936:S7S RS02040
gene id: 391936:S7S_RS02040
uniprot id: A0A0B4XIC3
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

391936:S7S RS16020
gene id: 391936:S7S_RS16020
uniprot id: A0A0B4XML4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

391936:S7S RS00590
gene id: 391936:S7S_RS00590
uniprot id: A0A0B4XJF1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS04840
gene id: 391936:S7S_RS04840
uniprot id: A0A0B4XM08
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

391936:S7S RS00540
gene id: 391936:S7S_RS00540
uniprot id: A0A0B4XJE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

391936:S7S RS14785
gene id: 391936:S7S_RS14785
uniprot id: A0A0B4XM42
names: Subcellular Location Annotation
messages: Cytoplasm

391936:S7S RS03690
gene id: 391936:S7S_RS03690
uniprot id: A0A0B4XJD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

391936:S7S RS00935
gene id: 391936:S7S_RS00935
uniprot id: A0A0B4XIS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

391936:S7S RS00725
gene id: 391936:S7S_RS00725
uniprot id: A0A0B4XEX7
names: Similarity
messages: Belongs to the GST superfamily.

391936:S7S RS01550
gene id: 391936:S7S_RS01550
uniprot id: A0A0B4XFB3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

391936:S7S RS01925
gene id: 391936:S7S_RS01925
uniprot id: A0A0B4XJR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

391936:S7S RS15075
gene id: 391936:S7S_RS15075
uniprot id: A0A0B4XSL2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

391936:S7S RS00275
gene id: 391936:S7S_RS00275
uniprot id: A0A0B4XEP7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

391936:S7S RS03790
gene id: 391936:S7S_RS03790
uniprot id: A0A0B4XJF6
names: Similarity
messages: Belongs to the YfgM family.

391936:S7S RS02825
gene id: 391936:S7S_RS02825
uniprot id: A0A0B4XIX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

391936:S7S RS13680
gene id: 391936:S7S_RS13680
uniprot id: A0A0B4XPL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

391936:S7S RS17160
gene id: 391936:S7S_RS17160
uniprot id: A0A0B4XSZ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS05400
gene id: 391936:S7S_RS05400
uniprot id: A0A0B4XH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS15670
gene id: 391936:S7S_RS15670
uniprot id: A0A0B4XRY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

391936:S7S RS13725
gene id: 391936:S7S_RS13725
uniprot id: A0A0B4XQR7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

391936:S7S RS17055
gene id: 391936:S7S_RS17055
uniprot id: A0A0B4XTH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS04810
gene id: 391936:S7S_RS04810
uniprot id: A0A0B4XJX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS00695
gene id: 391936:S7S_RS00695
uniprot id: A0A0B4XJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

391936:S7S RS15960
gene id: 391936:S7S_RS15960
uniprot id: A0A0B4XTE7
names: Similarity
messages: Belongs to the leucine-binding protein family.

391936:S7S RS09015
gene id: 391936:S7S_RS09015
uniprot id: A0A0B4XN76
names: Function
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

391936:S7S RS10770
gene id: 391936:S7S_RS10770
uniprot id: A0A0B4XP70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

391936:S7S RS11875
gene id: 391936:S7S_RS11875
uniprot id: A0A0B4XNS9
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS12560
gene id: 391936:S7S_RS12560
uniprot id: A0A0B4XR48
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

391936:S7S RS15475
gene id: 391936:S7S_RS15475
uniprot id: A0A0B4XQQ1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

391936:S7S RS08180
gene id: 391936:S7S_RS08180
uniprot id: A0A0B4XLP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

391936:S7S RS16800
gene id: 391936:S7S_RS16800
uniprot id: A0A0B4XMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

391936:S7S RS07870
gene id: 391936:S7S_RS07870
uniprot id: A0A0B4XLK7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

391936:S7S RS14720
gene id: 391936:S7S_RS14720
uniprot id: A0A0B4XQ46
names: Similarity
messages: Belongs to the type III secretion exporter family.

391936:S7S RS03460
gene id: 391936:S7S_RS03460
uniprot id: A0A0B4XJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

391936:S7S RS18130
gene id: 391936:S7S_RS18130
uniprot id: A0A0B4XU70
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

391936:S7S RS02820
gene id: 391936:S7S_RS02820
uniprot id: A0A0B4XK00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

391936:S7S RS04590
gene id: 391936:S7S_RS04590
uniprot id: A0A0B4XLU9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

391936:S7S RS17300
gene id: 391936:S7S_RS17300
uniprot id: A0A0B4XTM2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS12365
gene id: 391936:S7S_RS12365
uniprot id: A0A0B4XKR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

391936:S7S RS00475
gene id: 391936:S7S_RS00475
uniprot id: A0A0B4XES9
names: Similarity
messages: Belongs to the GSP E family.

391936:S7S RS03595
gene id: 391936:S7S_RS03595
uniprot id: A0A0B4XL82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

391936:S7S RS02795
gene id: 391936:S7S_RS02795
uniprot id: A0A0B4XIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

391936:S7S RS04765
gene id: 391936:S7S_RS04765
uniprot id: A0A0B4XLY8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

391936:S7S RS03840
gene id: 391936:S7S_RS03840
uniprot id: A0A0B4XJG6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

391936:S7S RS05795
gene id: 391936:S7S_RS05795
uniprot id: A0A0B4XKF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

391936:S7S RS13110
gene id: 391936:S7S_RS13110
uniprot id: A0A0B4XL92
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

391936:S7S RS00045
gene id: 391936:S7S_RS00045
uniprot id: A0A0B4XIQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

391936:S7S RS02900
gene id: 391936:S7S_RS02900
uniprot id: A0A0B4XIY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

391936:S7S RS16110
gene id: 391936:S7S_RS16110
uniprot id: A0A0B4XTI3
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS06700
gene id: 391936:S7S_RS06700
uniprot id: A0A0B4XMI5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS02220
gene id: 391936:S7S_RS02220
uniprot id: A0A0B4XKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

391936:S7S RS05915
gene id: 391936:S7S_RS05915
uniprot id: A0A0B4XLM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

391936:S7S RS06355
gene id: 391936:S7S_RS06355
uniprot id: A0A0B4XMY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

391936:S7S RS16705
gene id: 391936:S7S_RS16705
uniprot id: A0A0B4XSL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS10140
gene id: 391936:S7S_RS10140
uniprot id: A0A0B4XMV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

391936:S7S RS14020
gene id: 391936:S7S_RS14020
uniprot id: A0A0B4XLP1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

391936:S7S RS06180
gene id: 391936:S7S_RS06180
uniprot id: A0A0B4XMT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

391936:S7S RS04225
gene id: 391936:S7S_RS04225
uniprot id: A0A0B4XGM6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

391936:S7S RS04805
gene id: 391936:S7S_RS04805
uniprot id: A0A0B4XL13
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS04860
gene id: 391936:S7S_RS04860
uniprot id: A0A0B4XJY0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

391936:S7S RS16695
gene id: 391936:S7S_RS16695
uniprot id: A0A0B4XT94
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

391936:S7S RS12120
gene id: 391936:S7S_RS12120
uniprot id: A0A0B4XPY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

391936:S7S RS10580
gene id: 391936:S7S_RS10580
uniprot id: A0A0B4XJS5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

391936:S7S RS05470
gene id: 391936:S7S_RS05470
uniprot id: A0A0B4XLU8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

391936:S7S RS18180
gene id: 391936:S7S_RS18180
uniprot id: A0A0B4XU77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

391936:S7S RS03655
gene id: 391936:S7S_RS03655
uniprot id: A0A0B4XGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS17350
gene id: 391936:S7S_RS17350
uniprot id: A0A0B4XTN6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS04815
gene id: 391936:S7S_RS04815
uniprot id: A0A0B4XM00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

391936:S7S RS06735
gene id: 391936:S7S_RS06735
uniprot id: A0A0B4XM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS17665
gene id: 391936:S7S_RS17665
uniprot id: A0A0B4XTA2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

391936:S7S RS17105
gene id: 391936:S7S_RS17105
uniprot id: A0A0B4XTI0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

391936:S7S RS16100
gene id: 391936:S7S_RS16100
uniprot id: A0A0B4XS69
names: Similarity
messages: Belongs to the Gfa family.

391936:S7S RS06495
gene id: 391936:S7S_RS06495
uniprot id: A0A0B4XHR5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

391936:S7S RS09150
gene id: 391936:S7S_RS09150
uniprot id: A0A0B4XP22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS13465
gene id: 391936:S7S_RS13465
uniprot id: A0A0B4XRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

391936:S7S RS00765
gene id: 391936:S7S_RS00765
uniprot id: A0A0B4XJI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

391936:S7S RS07550
gene id: 391936:S7S_RS07550
uniprot id: A0A0B4XN64
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

391936:S7S RS10035
gene id: 391936:S7S_RS10035
uniprot id: A0A0B4XNR0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

391936:S7S RS13830
gene id: 391936:S7S_RS13830
uniprot id: A0A0B4XPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

391936:S7S RS18355
gene id: 391936:S7S_RS18355
uniprot id: A0A0B4XUA7
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS08565
gene id: 391936:S7S_RS08565
uniprot id: A0A0B4XN20
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

391936:S7S RS17545
gene id: 391936:S7S_RS17545
uniprot id: A0A0B4XRT1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

391936:S7S RS00390
gene id: 391936:S7S_RS00390
uniprot id: A0A0B4XJB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

391936:S7S RS09040
gene id: 391936:S7S_RS09040
uniprot id: A0A0B4XN80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

391936:S7S RS05935
gene id: 391936:S7S_RS05935
uniprot id: A0A0B4XHH6
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

391936:S7S RS04715
gene id: 391936:S7S_RS04715
uniprot id: A0A0B4XLX7
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

391936:S7S RS02965
gene id: 391936:S7S_RS02965
uniprot id: A0A0B4XG38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

391936:S7S RS12745
gene id: 391936:S7S_RS12745
uniprot id: A0A0B4XL39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YfcJ family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS10790
gene id: 391936:S7S_RS10790
uniprot id: A0A0B4XJW1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

391936:S7S RS07035
gene id: 391936:S7S_RS07035
uniprot id: A0A0B4XL21
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

391936:S7S RS14790
gene id: 391936:S7S_RS14790
uniprot id: A0A0B4XRE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

391936:S7S RS15340
gene id: 391936:S7S_RS15340
uniprot id: A0A0B4XMD6
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

391936:S7S RS11910
gene id: 391936:S7S_RS11910
uniprot id: A0A0B4XQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

391936:S7S RS06005
gene id: 391936:S7S_RS06005
uniprot id: A0A0B4XMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

391936:S7S RS17215
gene id: 391936:S7S_RS17215
uniprot id: A0A0B4XRL1
names: Similarity
messages: Belongs to the pyruvate kinase family.

391936:S7S RS01775
gene id: 391936:S7S_RS01775
uniprot id: A0A0B4XFF2
names: Similarity
messages: Belongs to the ComB family.

391936:S7S RS15490
gene id: 391936:S7S_RS15490
uniprot id: A0A0B4XMF3
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

391936:S7S RS11405
gene id: 391936:S7S_RS11405
uniprot id: A0A0B4XNK3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

391936:S7S RS11655
gene id: 391936:S7S_RS11655
uniprot id: A0A0B4XR68
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

391936:S7S RS03565
gene id: 391936:S7S_RS03565
uniprot id: A0A0B4XL79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

391936:S7S RS09665
gene id: 391936:S7S_RS09665
uniprot id: A0A0B4XNI6
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

391936:S7S RS12165
gene id: 391936:S7S_RS12165
uniprot id: A0A0B4XKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

391936:S7S RS02350
gene id: 391936:S7S_RS02350
uniprot id: A0A0B4XK11
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

391936:S7S RS00505
gene id: 391936:S7S_RS00505
uniprot id: A0A0B4XIK3
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS20005
gene id: 391936:S7S_RS20005
uniprot id: A0A0B4XPU9
names: Similarity
messages: Belongs to the transposase 8 family.

391936:S7S RS15080
gene id: 391936:S7S_RS15080
uniprot id: A0A0B4XM91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

391936:S7S RS02325
gene id: 391936:S7S_RS02325
uniprot id: A0A0B4XK06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

391936:S7S RS14135
gene id: 391936:S7S_RS14135
uniprot id: A0A0B4XSF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

391936:S7S RS18185
gene id: 391936:S7S_RS18185
uniprot id: A0A0B4XNU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

391936:S7S RS18300
gene id: 391936:S7S_RS18300
uniprot id: A0A0B4XUX6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS16070
gene id: 391936:S7S_RS16070
uniprot id: A0A0B4XMM0
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS16435
gene id: 391936:S7S_RS16435
uniprot id: A0A0B4XR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

391936:S7S RS05835
gene id: 391936:S7S_RS05835
uniprot id: A0A0B4XHF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

391936:S7S RS04185
gene id: 391936:S7S_RS04185
uniprot id: A0A0B4XJM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS11395
gene id: 391936:S7S_RS11395
uniprot id: A0A0B4XK71
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS04845
gene id: 391936:S7S_RS04845
uniprot id: A0A0B4XLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

391936:S7S RS18140
gene id: 391936:S7S_RS18140
uniprot id: A0A0B4XTL5
names: Similarity
messages: Belongs to the YggT family.

391936:S7S RS11155
gene id: 391936:S7S_RS11155
uniprot id: A0A0B4XQW8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

391936:S7S RS10655
gene id: 391936:S7S_RS10655
uniprot id: A0A0B4XQL3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

391936:S7S RS13475
gene id: 391936:S7S_RS13475
uniprot id: A0A0B4XQM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

391936:S7S RS10575
gene id: 391936:S7S_RS10575
uniprot id: A0A0B4XQ17
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS11730
gene id: 391936:S7S_RS11730
uniprot id: A0A0B4XR77
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS12395
gene id: 391936:S7S_RS12395
uniprot id: A0A0B4XQ45
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

391936:S7S RS00630
gene id: 391936:S7S_RS00630
uniprot id: A0A0B4XIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

391936:S7S RS00135
gene id: 391936:S7S_RS00135
uniprot id: A0A0B4XHC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

391936:S7S RS14330
gene id: 391936:S7S_RS14330
uniprot id: A0A0B4XSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

391936:S7S RS09710
gene id: 391936:S7S_RS09710
uniprot id: A0A0B4XJ73
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

391936:S7S RS13720
gene id: 391936:S7S_RS13720
uniprot id: A0A0B4XLI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

391936:S7S RS07515
gene id: 391936:S7S_RS07515
uniprot id: A0A0B4XLB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS16310
gene id: 391936:S7S_RS16310
uniprot id: A0A0B4XR40
names: Subcellular Location Annotation
messages: Cytoplasm

391936:S7S RS09620
gene id: 391936:S7S_RS09620
uniprot id: A0A0B4XMG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

391936:S7S RS18365
gene id: 391936:S7S_RS18365
uniprot id: A0A0B4XTR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

391936:S7S RS07805
gene id: 391936:S7S_RS07805
uniprot id: A0A0B4XND9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

391936:S7S RS07365
gene id: 391936:S7S_RS07365
uniprot id: A0A0B4XL85
names: Subcellular Location Annotation
messages: Cell inner membrane

391936:S7S RS01195
gene id: 391936:S7S_RS01195
uniprot id: A0A0B4XJC3
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

391936:S7S RS01715
gene id: 391936:S7S_RS01715
uniprot id: A0A0B4XK15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS12475
gene id: 391936:S7S_RS12475
uniprot id: A0A0B4XP58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

391936:S7S RS18005
gene id: 391936:S7S_RS18005
uniprot id: A0A0B4XU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

391936:S7S RS09755
gene id: 391936:S7S_RS09755
uniprot id: A0A0B4XPG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

391936:S7S RS15060
gene id: 391936:S7S_RS15060
uniprot id: A0A0B4XRL3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

391936:S7S RS16700
gene id: 391936:S7S_RS16700
uniprot id: A0A0B4XMW4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

391936:S7S RS16315
gene id: 391936:S7S_RS16315
uniprot id: A0A0B4XTM7
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

391936:S7S RS15720
gene id: 391936:S7S_RS15720
uniprot id: A0A0B4XRZ6
names: Similarity
messages: Belongs to the CFA/CMAS family.

391936:S7S RS09010
gene id: 391936:S7S_RS09010
uniprot id: A0A0B4XIS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

391936:S7S RS11725
gene id: 391936:S7S_RS11725
uniprot id: A0A0B4XNQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS15950
gene id: 391936:S7S_RS15950
uniprot id: A0A0B4XS40
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

391936:S7S RS08990
gene id: 391936:S7S_RS08990
uniprot id: A0A0B4XN71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

391936:S7S RS18470
gene id: 391936:S7S_RS18470
uniprot id: A0A0B4XSB7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

391936:S7S RS04660
gene id: 391936:S7S_RS04660
uniprot id: A0A0B4XJU7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS15590
gene id: 391936:S7S_RS15590
uniprot id: A0A0B4XMG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

391936:S7S RS00985
gene id: 391936:S7S_RS00985
uniprot id: A0A0B4XHS8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

391936:S7S RS02995
gene id: 391936:S7S_RS02995
uniprot id: A0A0B4XIZ9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

391936:S7S RS02600
gene id: 391936:S7S_RS02600
uniprot id: A0A0B4XJW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS13770
gene id: 391936:S7S_RS13770
uniprot id: A0A0B4XLI7
names: Similarity
messages: Belongs to the UPF0250 family.

391936:S7S RS11345
gene id: 391936:S7S_RS11345
uniprot id: A0A0B4XK56
names: Similarity
messages: Belongs to the cytochrome P450 family.

391936:S7S RS16930
gene id: 391936:S7S_RS16930
uniprot id: A0A0B4XU21
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

391936:S7S RS09545
gene id: 391936:S7S_RS09545
uniprot id: A0A0B4XME2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

391936:S7S RS18100
gene id: 391936:S7S_RS18100
uniprot id: A0A0B4XUU1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS07600
gene id: 391936:S7S_RS07600
uniprot id: A0A0B4XN77
names: Similarity
messages: Belongs to the CcdB toxin family.

391936:S7S RS11565
gene id: 391936:S7S_RS11565
uniprot id: A0A0B4XPN6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

391936:S7S RS00185
gene id: 391936:S7S_RS00185
uniprot id: A0A0B4XHD4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

391936:S7S RS18840
gene id: 391936:S7S_RS18840
uniprot id: A0A0B4XMU6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

391936:S7S RS17670
gene id: 391936:S7S_RS17670
uniprot id: A0A0B4XRW2
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

391936:S7S RS00625
gene id: 391936:S7S_RS00625
uniprot id: A0A0B4XEV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

391936:S7S RS10375
gene id: 391936:S7S_RS10375
uniprot id: A0A0B4XN37
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS10030
gene id: 391936:S7S_RS10030
uniprot id: A0A0B4XJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

391936:S7S RS05770
gene id: 391936:S7S_RS05770
uniprot id: A0A0B4XKF5
names: Similarity
messages: Belongs to the elongation factor P family.

391936:S7S RS10215
gene id: 391936:S7S_RS10215
uniprot id: A0A0B4XMZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

391936:S7S RS03575
gene id: 391936:S7S_RS03575
uniprot id: A0A0B4XGA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

391936:S7S RS02895
gene id: 391936:S7S_RS02895
uniprot id: A0A0B4XK12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

391936:S7S RS10875
gene id: 391936:S7S_RS10875
uniprot id: A0A0B4XNB5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

391936:S7S RS10220
gene id: 391936:S7S_RS10220
uniprot id: A0A0B4XQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

391936:S7S RS17810
gene id: 391936:S7S_RS17810
uniprot id: A0A0B4XNP0
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

391936:S7S RS13170
gene id: 391936:S7S_RS13170
uniprot id: A0A0B4XQH2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

391936:S7S RS10450
gene id: 391936:S7S_RS10450
uniprot id: A0A0B4XP08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

391936:S7S RS05840
gene id: 391936:S7S_RS05840
uniprot id: A0A0B4XLL7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

391936:S7S RS04610
gene id: 391936:S7S_RS04610
uniprot id: A0A0B4XJT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS17210
gene id: 391936:S7S_RS17210
uniprot id: A0A0B4XT07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

391936:S7S RS01705
gene id: 391936:S7S_RS01705
uniprot id: A0A0B4XJ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

391936:S7S RS03225
gene id: 391936:S7S_RS03225
uniprot id: A0A0B4XL22
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

391936:S7S RS01660
gene id: 391936:S7S_RS01660
uniprot id: A0A0B4XI56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

391936:S7S RS12605
gene id: 391936:S7S_RS12605
uniprot id: A0A0B4XRP1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS02260
gene id: 391936:S7S_RS02260
uniprot id: A0A0B4XJK5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. KdkA/rfaP family.
messages: Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core.

391936:S7S RS14860
gene id: 391936:S7S_RS14860
uniprot id: A0A0B4XM55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

391936:S7S RS00220
gene id: 391936:S7S_RS00220
uniprot id: A0A0B4XIU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS03190
gene id: 391936:S7S_RS03190
uniprot id: A0A0B4XK53
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

391936:S7S RS01935
gene id: 391936:S7S_RS01935
uniprot id: A0A0B4XJE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

391936:S7S RS14910
gene id: 391936:S7S_RS14910
uniprot id: A0A0B4XM64
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

391936:S7S RS04475
gene id: 391936:S7S_RS04475
uniprot id: A0A0B4XGS3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

391936:S7S RS00730
gene id: 391936:S7S_RS00730
uniprot id: A0A0B4XIP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS17280
gene id: 391936:S7S_RS17280
uniprot id: A0A0B4XN99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS08440
gene id: 391936:S7S_RS08440
uniprot id: A0A0B4XN09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

391936:S7S RS11670
gene id: 391936:S7S_RS11670
uniprot id: A0A0B4XPP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS15905
gene id: 391936:S7S_RS15905
uniprot id: A0A0B4XQW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

391936:S7S RS05065
gene id: 391936:S7S_RS05065
uniprot id: A0A0B4XM71
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

391936:S7S RS08630
gene id: 391936:S7S_RS08630
uniprot id: A0A0B4XNT1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

391936:S7S RS09910
gene id: 391936:S7S_RS09910
uniprot id: A0A0B4XJC4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

391936:S7S RS12185
gene id: 391936:S7S_RS12185
uniprot id: A0A0B4XQW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

391936:S7S RS07290
gene id: 391936:S7S_RS07290
uniprot id: A0A0B4XL71
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

391936:S7S RS16580
gene id: 391936:S7S_RS16580
uniprot id: A0A0B4XTU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

391936:S7S RS17430
gene id: 391936:S7S_RS17430
uniprot id: A0A0B4XTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

391936:S7S RS13225
gene id: 391936:S7S_RS13225
uniprot id: A0A0B4XS22
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

391936:S7S RS14700
gene id: 391936:S7S_RS14700
uniprot id: A0A0B4XSP9
names: Similarity
messages: Belongs to the MotB family.

391936:S7S RS11925
gene id: 391936:S7S_RS11925
uniprot id: A0A0B4XNT9
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS10825
gene id: 391936:S7S_RS10825
uniprot id: A0A0B4XNA7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS04245
gene id: 391936:S7S_RS04245
uniprot id: A0A0B4XL15
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS00485
gene id: 391936:S7S_RS00485
uniprot id: A0A0B4XHJ0
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS03605
gene id: 391936:S7S_RS03605
uniprot id: A0A0B4XGB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

391936:S7S RS06025
gene id: 391936:S7S_RS06025
uniprot id: A0A0B4XKJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

391936:S7S RS15500
gene id: 391936:S7S_RS15500
uniprot id: A0A0B4XQQ5
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

391936:S7S RS03200
gene id: 391936:S7S_RS03200
uniprot id: A0A0B4XL19
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

391936:S7S RS16035
gene id: 391936:S7S_RS16035
uniprot id: A0A0B4XTG5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

391936:S7S RS01975
gene id: 391936:S7S_RS01975
uniprot id: A0A0B4XJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

391936:S7S RS06070
gene id: 391936:S7S_RS06070
uniprot id: A0A0B4XLQ8
names: Similarity
messages: Belongs to the WrbA family.

391936:S7S RS15205
gene id: 391936:S7S_RS15205
uniprot id: A0A0B4XSQ6
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS12090
gene id: 391936:S7S_RS12090
uniprot id: A0A0B4XKK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

391936:S7S RS18065
gene id: 391936:S7S_RS18065
uniprot id: A0A0B4XTK1
names: Similarity
messages: Belongs to the universal stress protein A family.

391936:S7S RS09290
gene id: 391936:S7S_RS09290
uniprot id: A0A0B4XM84
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

391936:S7S RS03310
gene id: 391936:S7S_RS03310
uniprot id: A0A0B4XL35
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

391936:S7S RS03295
gene id: 391936:S7S_RS03295
uniprot id: A0A0B4XG76
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS01345
gene id: 391936:S7S_RS01345
uniprot id: A0A0B4XF86
names: Similarity
messages: Belongs to the HSP15 family.

391936:S7S RS00405
gene id: 391936:S7S_RS00405
uniprot id: A0A0B4XII4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

391936:S7S RS10905
gene id: 391936:S7S_RS10905
uniprot id: A0A0B4XQR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

391936:S7S RS12455
gene id: 391936:S7S_RS12455
uniprot id: A0A0B4XRK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

391936:S7S RS10165
gene id: 391936:S7S_RS10165
uniprot id: A0A0B4XMW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

391936:S7S RS14710
gene id: 391936:S7S_RS14710
uniprot id: A0A0B4XM31
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

391936:S7S RS12450
gene id: 391936:S7S_RS12450
uniprot id: A0A0B4XP52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

391936:S7S RS13505
gene id: 391936:S7S_RS13505
uniprot id: A0A0B4XPJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

391936:S7S RS18200
gene id: 391936:S7S_RS18200
uniprot id: A0A0B4XUV5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

391936:S7S RS09975
gene id: 391936:S7S_RS09975
uniprot id: A0A0B4XPM5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

391936:S7S RS00140
gene id: 391936:S7S_RS00140
uniprot id: A0A0B4XJ93
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

391936:S7S RS06505
gene id: 391936:S7S_RS06505
uniprot id: A0A0B4XKT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS06750
gene id: 391936:S7S_RS06750
uniprot id: A0A0B4XMJ7
names: Similarity
messages: Belongs to the UPF0270 family.

391936:S7S RS08875
gene id: 391936:S7S_RS08875
uniprot id: A0A0B4XPI4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS03235
gene id: 391936:S7S_RS03235
uniprot id: A0A0B4XG67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

391936:S7S RS08015
gene id: 391936:S7S_RS08015
uniprot id: A0A0B4XNH6
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

391936:S7S RS11070
gene id: 391936:S7S_RS11070
uniprot id: A0A0B4XPC6
names: Similarity
messages: Belongs to the pirin family.

391936:S7S RS15810
gene id: 391936:S7S_RS15810
uniprot id: A0A0B4XTC2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

391936:S7S RS15780
gene id: 391936:S7S_RS15780
uniprot id: A0A0B4XTB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

391936:S7S RS02865
gene id: 391936:S7S_RS02865
uniprot id: A0A0B4XG29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

391936:S7S RS00205
gene id: 391936:S7S_RS00205
uniprot id: A0A0B4XID8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

391936:S7S RS13065
gene id: 391936:S7S_RS13065
uniprot id: A0A0B4XQF9
names: Similarity
messages: Belongs to the UPF0178 family.

391936:S7S RS00020
gene id: 391936:S7S_RS00020
uniprot id: A0A0B4XIQ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

391936:S7S RS16155
gene id: 391936:S7S_RS16155
uniprot id: A0A0B4XR13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS00570
gene id: 391936:S7S_RS00570
uniprot id: A0A0B4XIZ7
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

391936:S7S RS03725
gene id: 391936:S7S_RS03725
uniprot id: A0A0B4XKR5
names: Similarity
messages: Belongs to the SufE family.

391936:S7S RS08280
gene id: 391936:S7S_RS08280
uniprot id: A0A0B4XLR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

391936:S7S RS07570
gene id: 391936:S7S_RS07570
uniprot id: A0A0B4XNR4
names: Similarity
messages: Belongs to the peptidase S45 family.

391936:S7S RS14775
gene id: 391936:S7S_RS14775
uniprot id: A0A0B4XSR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

391936:S7S RS05755
gene id: 391936:S7S_RS05755
uniprot id: A0A0B4XML3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

391936:S7S RS11945
gene id: 391936:S7S_RS11945
uniprot id: A0A0B4XKH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

391936:S7S RS01410
gene id: 391936:S7S_RS01410
uniprot id: A0A0B4XI07
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

391936:S7S RS16640
gene id: 391936:S7S_RS16640
uniprot id: A0A0B4XTV5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

391936:S7S RS16910
gene id: 391936:S7S_RS16910
uniprot id: A0A0B4XRF2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

391936:S7S RS12060
gene id: 391936:S7S_RS12060
uniprot id: A0A0B4XQU2
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

391936:S7S RS03580
gene id: 391936:S7S_RS03580
uniprot id: A0A0B4XKA6
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS01580
gene id: 391936:S7S_RS01580
uniprot id: A0A0B4XJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

391936:S7S RS01465
gene id: 391936:S7S_RS01465
uniprot id: A0A0B4XI16
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS15865
gene id: 391936:S7S_RS15865
uniprot id: A0A0B4XSX9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS06415
gene id: 391936:S7S_RS06415
uniprot id: A0A0B4XMA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

391936:S7S RS02875
gene id: 391936:S7S_RS02875
uniprot id: A0A0B4XIX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

391936:S7S RS03630
gene id: 391936:S7S_RS03630
uniprot id: A0A0B4XGB2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

391936:S7S RS15100
gene id: 391936:S7S_RS15100
uniprot id: A0A0B4XSL8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

391936:S7S RS01645
gene id: 391936:S7S_RS01645
uniprot id: A0A0B4XJK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

391936:S7S RS18810
gene id: 391936:S7S_RS18810
uniprot id: A0A0B4XI17
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

391936:S7S RS03755
gene id: 391936:S7S_RS03755
uniprot id: A0A0B4XGD5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

391936:S7S RS18310
gene id: 391936:S7S_RS18310
uniprot id: A0A0B4XNX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

391936:S7S RS09875
gene id: 391936:S7S_RS09875
uniprot id: A0A0B4XQ35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

391936:S7S RS12375
gene id: 391936:S7S_RS12375
uniprot id: A0A0B4XP34
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

391936:S7S RS13595
gene id: 391936:S7S_RS13595
uniprot id: A0A0B4XLG2
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS02990
gene id: 391936:S7S_RS02990
uniprot id: A0A0B4XK27
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

391936:S7S RS07485
gene id: 391936:S7S_RS07485
uniprot id: A0A0B4XMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

391936:S7S RS06165
gene id: 391936:S7S_RS06165
uniprot id: A0A0B4XHK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

391936:S7S RS15630
gene id: 391936:S7S_RS15630
uniprot id: A0A0B4XT93
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

391936:S7S RS05055
gene id: 391936:S7S_RS05055
uniprot id: A0A0B4XL68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

391936:S7S RS00665
gene id: 391936:S7S_RS00665
uniprot id: A0A0B4XJG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

391936:S7S RS07920
gene id: 391936:S7S_RS07920
uniprot id: A0A0B4XLL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS12275
gene id: 391936:S7S_RS12275
uniprot id: A0A0B4XP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

391936:S7S RS10815
gene id: 391936:S7S_RS10815
uniprot id: A0A0B4XJW5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS09540
gene id: 391936:S7S_RS09540
uniprot id: A0A0B4XNG5
names: Similarity
messages: Belongs to the cytochrome P450 family.

391936:S7S RS12220
gene id: 391936:S7S_RS12220
uniprot id: A0A0B4XQ06
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

391936:S7S RS01175
gene id: 391936:S7S_RS01175
uniprot id: A0A0B4XF55
names: Similarity
messages: Belongs to the RelE toxin family.

391936:S7S RS08880
gene id: 391936:S7S_RS08880
uniprot id: A0A0B4XNW6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

391936:S7S RS14830
gene id: 391936:S7S_RS14830
uniprot id: A0A0B4XSG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

391936:S7S RS08625
gene id: 391936:S7S_RS08625
uniprot id: A0A0B4XPC1
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS12105
gene id: 391936:S7S_RS12105
uniprot id: A0A0B4XRD9
names: Subcellular Location Annotation
messages: Cytoplasm

391936:S7S RS16785
gene id: 391936:S7S_RS16785
uniprot id: A0A0B4XRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

391936:S7S RS08555
gene id: 391936:S7S_RS08555
uniprot id: A0A0B4XNR7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-59 and Arg-62) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

391936:S7S RS17155
gene id: 391936:S7S_RS17155
uniprot id: A0A0B4XN78
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS04005
gene id: 391936:S7S_RS04005
uniprot id: A0A0B4XKI9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

391936:S7S RS03330
gene id: 391936:S7S_RS03330
uniprot id: A0A0B4XJ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

391936:S7S RS02225
gene id: 391936:S7S_RS02225
uniprot id: A0A0B4XJY1
names: Similarity
messages: Belongs to the UPF0111 family.

391936:S7S RS14805
gene id: 391936:S7S_RS14805
uniprot id: A0A0B4XSG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

391936:S7S RS08580
gene id: 391936:S7S_RS08580
uniprot id: A0A0B4XNS2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

391936:S7S RS12020
gene id: 391936:S7S_RS12020
uniprot id: A0A0B4XKJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

391936:S7S RS03800
gene id: 391936:S7S_RS03800
uniprot id: A0A0B4XKS3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

391936:S7S RS15560
gene id: 391936:S7S_RS15560
uniprot id: A0A0B4XSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

391936:S7S RS13970
gene id: 391936:S7S_RS13970
uniprot id: A0A0B4XLN2
names: Similarity
messages: Belongs to the DEAD box helicase family.

391936:S7S RS07010
gene id: 391936:S7S_RS07010
uniprot id: A0A0B4XL17
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

391936:S7S RS02940
gene id: 391936:S7S_RS02940
uniprot id: A0A0B4XG36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

391936:S7S RS10460
gene id: 391936:S7S_RS10460
uniprot id: A0A0B4XQI5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

391936:S7S RS04425
gene id: 391936:S7S_RS04425
uniprot id: A0A0B4XGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS13565
gene id: 391936:S7S_RS13565
uniprot id: A0A0B4XRN2
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

391936:S7S RS02035
gene id: 391936:S7S_RS02035
uniprot id: A0A0B4XJG3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

391936:S7S RS01670
gene id: 391936:S7S_RS01670
uniprot id: A0A0B4XJK8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

391936:S7S RS09485
gene id: 391936:S7S_RS09485
uniprot id: A0A0B4XJ24
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

391936:S7S RS00255
gene id: 391936:S7S_RS00255
uniprot id: A0A0B4XIF1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

391936:S7S RS13240
gene id: 391936:S7S_RS13240
uniprot id: A0A0B4XQI4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

391936:S7S RS04795
gene id: 391936:S7S_RS04795
uniprot id: A0A0B4XLE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

391936:S7S RS08750
gene id: 391936:S7S_RS08750
uniprot id: A0A0B4XPF0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

391936:S7S RS00155
gene id: 391936:S7S_RS00155
uniprot id: A0A0B4XID0
names: Similarity
messages: Belongs to the DprA/Smf family.

391936:S7S RS17940
gene id: 391936:S7S_RS17940
uniprot id: A0A0B4XTH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

391936:S7S RS07275
gene id: 391936:S7S_RS07275
uniprot id: A0A0B4XMY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

391936:S7S RS01310
gene id: 391936:S7S_RS01310
uniprot id: A0A0B4XJT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

391936:S7S RS15690
gene id: 391936:S7S_RS15690
uniprot id: A0A0B4XMH4
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

391936:S7S RS17100
gene id: 391936:S7S_RS17100
uniprot id: A0A0B4XU61
names: Similarity
messages: Belongs to the YoeB family.

391936:S7S RS17860
gene id: 391936:S7S_RS17860
uniprot id: A0A0B4XNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

391936:S7S RS04905
gene id: 391936:S7S_RS04905
uniprot id: A0A0B4XL33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

391936:S7S RS00480
gene id: 391936:S7S_RS00480
uniprot id: A0A0B4XIJ9
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS12390
gene id: 391936:S7S_RS12390
uniprot id: A0A0B4XKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

391936:S7S RS16565
gene id: 391936:S7S_RS16565
uniprot id: A0A0B4XMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

391936:S7S RS02765
gene id: 391936:S7S_RS02765
uniprot id: A0A0B4XG20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS15260
gene id: 391936:S7S_RS15260
uniprot id: A0A0B4XSR7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS09895
gene id: 391936:S7S_RS09895
uniprot id: A0A0B4XMP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

391936:S7S RS12975
gene id: 391936:S7S_RS12975
uniprot id: A0A0B4XRY9
names: Similarity
messages: Belongs to the UPF0145 family.

391936:S7S RS01495
gene id: 391936:S7S_RS01495
uniprot id: A0A0B4XJW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

391936:S7S RS17170
gene id: 391936:S7S_RS17170
uniprot id: A0A0B4XU81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

391936:S7S RS17440
gene id: 391936:S7S_RS17440
uniprot id: A0A0B4XT55
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

391936:S7S RS12725
gene id: 391936:S7S_RS12725
uniprot id: A0A0B4XQB9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

391936:S7S RS01795
gene id: 391936:S7S_RS01795
uniprot id: A0A0B4XJN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

391936:S7S RS14735
gene id: 391936:S7S_RS14735
uniprot id: A0A0B4XM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

391936:S7S RS00515
gene id: 391936:S7S_RS00515
uniprot id: A0A0B4XJD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

391936:S7S RS13350
gene id: 391936:S7S_RS13350
uniprot id: A0A0B4XPI2
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

391936:S7S RS02210
gene id: 391936:S7S_RS02210
uniprot id: A0A0B4XJJ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS14650
gene id: 391936:S7S_RS14650
uniprot id: A0A0B4XQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

391936:S7S RS13845
gene id: 391936:S7S_RS13845
uniprot id: A0A0B4XLK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

391936:S7S RS16630
gene id: 391936:S7S_RS16630
uniprot id: A0A0B4XSJ6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

391936:S7S RS12285
gene id: 391936:S7S_RS12285
uniprot id: A0A0B4XQY7
names: Similarity
messages: Belongs to the glutamine synthetase family.

391936:S7S RS12500
gene id: 391936:S7S_RS12500
uniprot id: A0A0B4XP66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

391936:S7S RS08075
gene id: 391936:S7S_RS08075
uniprot id: A0A0B4XMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

391936:S7S RS09790
gene id: 391936:S7S_RS09790
uniprot id: A0A0B4XNK7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

391936:S7S RS02920
gene id: 391936:S7S_RS02920
uniprot id: A0A0B4XK14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

391936:S7S RS16880
gene id: 391936:S7S_RS16880
uniprot id: A0A0B4XSQ1
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

391936:S7S RS17195
gene id: 391936:S7S_RS17195
uniprot id: A0A0B4XTJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

391936:S7S RS14050
gene id: 391936:S7S_RS14050
uniprot id: A0A0B4XQY4
names: Similarity
messages: Belongs to the GARS family.

391936:S7S RS01245
gene id: 391936:S7S_RS01245
uniprot id: A0A0B4XJD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

391936:S7S RS10170
gene id: 391936:S7S_RS10170
uniprot id: A0A0B4XQ96
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

391936:S7S RS10955
gene id: 391936:S7S_RS10955
uniprot id: A0A0B4XQS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

391936:S7S RS08825
gene id: 391936:S7S_RS08825
uniprot id: A0A0B4XPH0
names: Similarity
messages: Belongs to the Lgt family.

391936:S7S RS10795
gene id: 391936:S7S_RS10795
uniprot id: A0A0B4XP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

391936:S7S RS08670
gene id: 391936:S7S_RS08670
uniprot id: A0A0B4XLX3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

391936:S7S RS09270
gene id: 391936:S7S_RS09270
uniprot id: A0A0B4XPR9
names: Similarity
messages: Belongs to the UPF0246 family.

391936:S7S RS15675
gene id: 391936:S7S_RS15675
uniprot id: A0A0B4XQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS14845
gene id: 391936:S7S_RS14845
uniprot id: A0A0B4XQ76
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

391936:S7S RS07120
gene id: 391936:S7S_RS07120
uniprot id: A0A0B4XMT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

391936:S7S RS12630
gene id: 391936:S7S_RS12630
uniprot id: A0A0B4XRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

391936:S7S RS11880
gene id: 391936:S7S_RS11880
uniprot id: A0A0B4XRA0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

391936:S7S RS04365
gene id: 391936:S7S_RS04365
uniprot id: A0A0B4XLP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

391936:S7S RS02620
gene id: 391936:S7S_RS02620
uniprot id: A0A0B4XG08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

391936:S7S RS01610
gene id: 391936:S7S_RS01610
uniprot id: A0A0B4XI46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

391936:S7S RS02165
gene id: 391936:S7S_RS02165
uniprot id: A0A0B4XIF5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

391936:S7S RS10455
gene id: 391936:S7S_RS10455
uniprot id: A0A0B4XN50
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

391936:S7S RS03910
gene id: 391936:S7S_RS03910
uniprot id: A0A0B4XKG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

391936:S7S RS03760
gene id: 391936:S7S_RS03760
uniprot id: A0A0B4XKD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

391936:S7S RS02000
gene id: 391936:S7S_RS02000
uniprot id: A0A0B4XJT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

391936:S7S RS12635
gene id: 391936:S7S_RS12635
uniprot id: A0A0B4XR67
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

391936:S7S RS11260
gene id: 391936:S7S_RS11260
uniprot id: A0A0B4XQY6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

391936:S7S RS12855
gene id: 391936:S7S_RS12855
uniprot id: A0A0B4XPD4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

391936:S7S RS17720
gene id: 391936:S7S_RS17720
uniprot id: A0A0B4XRY7
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

391936:S7S RS15655
gene id: 391936:S7S_RS15655
uniprot id: A0A0B4XT98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

391936:S7S RS00940
gene id: 391936:S7S_RS00940
uniprot id: A0A0B4XJL3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

391936:S7S RS02810
gene id: 391936:S7S_RS02810
uniprot id: A0A0B4XKD9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

391936:S7S RS13570
gene id: 391936:S7S_RS13570
uniprot id: A0A0B4XLF9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS03650
gene id: 391936:S7S_RS03650
uniprot id: A0A0B4XKQ5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

391936:S7S RS07940
gene id: 391936:S7S_RS07940
uniprot id: A0A0B4XMW3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

391936:S7S RS03750
gene id: 391936:S7S_RS03750
uniprot id: A0A0B4XKR7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

391936:S7S RS02840
gene id: 391936:S7S_RS02840
uniprot id: A0A0B4XG24
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

391936:S7S RS05845
gene id: 391936:S7S_RS05845
uniprot id: A0A0B4XKG8
names: Similarity
messages: Belongs to the TPP enzyme family.

391936:S7S RS08295
gene id: 391936:S7S_RS08295
uniprot id: A0A0B4XIJ8
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS10810
gene id: 391936:S7S_RS10810
uniprot id: A0A0B4XQ47
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

391936:S7S RS18315
gene id: 391936:S7S_RS18315
uniprot id: A0A0B4XTQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

391936:S7S RS12660
gene id: 391936:S7S_RS12660
uniprot id: A0A0B4XRQ6
names: Similarity
messages: Belongs to the DEAD box helicase family.

391936:S7S RS08050
gene id: 391936:S7S_RS08050
uniprot id: A0A0B4XMX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

391936:S7S RS01335
gene id: 391936:S7S_RS01335
uniprot id: A0A0B4XJU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

391936:S7S RS18110
gene id: 391936:S7S_RS18110
uniprot id: A0A0B4XNU0
names: Similarity
messages: Belongs to the pirin family.

391936:S7S RS18640
gene id: 391936:S7S_RS18640
uniprot id: A0A0B4XP35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

391936:S7S RS06820
gene id: 391936:S7S_RS06820
uniprot id: A0A0B4XN90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

391936:S7S RS12695
gene id: 391936:S7S_RS12695
uniprot id: A0A0B4XKZ5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

391936:S7S RS12085
gene id: 391936:S7S_RS12085
uniprot id: A0A0B4XQU7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

391936:S7S RS16425
gene id: 391936:S7S_RS16425
uniprot id: A0A0B4XMR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

391936:S7S RS14880
gene id: 391936:S7S_RS14880
uniprot id: A0A0B4XSH5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

391936:S7S RS10080
gene id: 391936:S7S_RS10080
uniprot id: A0A0B4XJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

391936:S7S RS08485
gene id: 391936:S7S_RS08485
uniprot id: A0A0B4XIL5
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

391936:S7S RS00015
gene id: 391936:S7S_RS00015
uniprot id: A0A0B4XJ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

391936:S7S RS12525
gene id: 391936:S7S_RS12525
uniprot id: A0A0B4XP72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

391936:S7S RS11960
gene id: 391936:S7S_RS11960
uniprot id: A0A0B4XRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

391936:S7S RS16995
gene id: 391936:S7S_RS16995
uniprot id: A0A0B4XRH0
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

391936:S7S RS00085
gene id: 391936:S7S_RS00085
uniprot id: A0A0B4XH96
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

391936:S7S RS14685
gene id: 391936:S7S_RS14685
uniprot id: A0A0B4XM29
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

391936:S7S RS15635
gene id: 391936:S7S_RS15635
uniprot id: A0A0B4XSV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

391936:S7S RS17360
gene id: 391936:S7S_RS17360
uniprot id: A0A0B4XT40
names: Subcellular Location Annotation
messages: Membrane

391936:S7S RS02910
gene id: 391936:S7S_RS02910
uniprot id: A0A0B4XKF8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

391936:S7S RS16600
gene id: 391936:S7S_RS16600
uniprot id: A0A0B4XMU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

391936:S7S RS04625
gene id: 391936:S7S_RS04625
uniprot id: A0A0B4XGU7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

391936:S7S RS01555
gene id: 391936:S7S_RS01555
uniprot id: A0A0B4XJ56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

391936:S7S RS11150
gene id: 391936:S7S_RS11150
uniprot id: A0A0B4XNG0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

391936:S7S RS07455
gene id: 391936:S7S_RS07455
uniprot id: A0A0B4XI95
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

391936:S7S RS11870
gene id: 391936:S7S_RS11870
uniprot id: A0A0B4XPT3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

391936:S7S RS12380
gene id: 391936:S7S_RS12380
uniprot id: A0A0B4XRI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

391936:S7S RS15460
gene id: 391936:S7S_RS15460
uniprot id: A0A0B4XSU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

391936:S7S RS02170
gene id: 391936:S7S_RS02170
uniprot id: A0A0B4XKC4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

391936:S7S RS11255
gene id: 391936:S7S_RS11255
uniprot id: A0A0B4XNI0
names: Similarity
messages: Belongs to the aspartokinase family.

391936:S7S RS08715
gene id: 391936:S7S_RS08715
uniprot id: A0A0B4XN35
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

391936:S7S RS00145
gene id: 391936:S7S_RS00145
uniprot id: A0A0B4XIT6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

391936:S7S RS14025
gene id: 391936:S7S_RS14025
uniprot id: A0A0B4XQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

391936:S7S RS04500
gene id: 391936:S7S_RS04500
uniprot id: A0A0B4XGS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane